Farhang Alem - Publications

Affiliations: 
School of Systems Biology George Mason University, Washington, DC 

23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2025 Tieu KV, Espey M, Narayanan A, Heise RL, Alem F, Conway DE. SARS-CoV-2 S-protein expression drives syncytia formation in endothelial cells. Scientific Reports. 15: 3549. PMID 39875448 DOI: 10.1038/s41598-025-86242-1  0.371
2024 Adeyinka OS, Barrera MD, Metibemu DS, Boghdeh N, Anderson CA, Baha H, Crown O, Falode JA, Bleach JL, Bliss AR, Hampton TP, Ojobor JC, Alem F, Narayanan A, Ogungbe IV. nsP2 Protease Inhibitor Blocks the Replication of New World Alphaviruses and Offer Protection in Mice. Acs Infectious Diseases. PMID 39737550 DOI: 10.1021/acsinfecdis.4c00701  0.515
2024 Sreepangi S, Baha H, Opoku LA, Jones NX, Konadu M, Alem F, Barrera MD, Narayanan A. Host-Driven Ubiquitination Events in Vector-Transmitted RNA Virus Infections as Options for Broad-Spectrum Therapeutic Intervention Strategies. Viruses. 16. PMID 39599842 DOI: 10.3390/v16111727  0.553
2024 Adhikari RP, Alem F, Kemboi D, Kanipakala T, Sherchand SP, Kailasan S, Purcell BK, Heine HS, Russell-Lodrigue K, Etobayeva I, Howell KA, Vu H, Shulenin S, Holtsberg FW, Roy CJ, et al. Engineered antibodies targeted to bacterial surface integrate effector functions with toxin neutralization to provide superior efficacy against bacterial infections. Medrxiv : the Preprint Server For Health Sciences. PMID 39398995 DOI: 10.1101/2024.09.23.24313920  0.73
2024 Alem F, Brahms A, Tarasaki K, Omole S, Kehn-Hall K, Schmaljohn CS, Bavari S, Makino S, Hakami RM. HSP90 is part of a protein complex with the L polymerase of Rift Valley fever phlebovirus and prevents its degradation by the proteasome during the viral genome replication/transcription stage. Frontiers in Cellular and Infection Microbiology. 14: 1331755. PMID 38800833 DOI: 10.3389/fcimb.2024.1331755  0.75
2024 Faley SL, Boghdeh NA, Schaffer DK, Spivey EC, Alem F, Narayanan A, Wikswo JP, Brown JA. Gravity-perfused airway-on-a-chip optimized for quantitative BSL-3 studies of SARS-CoV-2 infection: barrier permeability, cytokine production, immunohistochemistry, and viral load assays. Lab On a Chip. PMID 38362777 DOI: 10.1039/d3lc00894k  0.354
2023 Anderson CA, Barrera MD, Boghdeh NA, Smith M, Alem F, Narayanan A. Brilacidin as a Broad-Spectrum Inhibitor of Enveloped, Acutely Infectious Viruses. Microorganisms. 12. PMID 38257881 DOI: 10.3390/microorganisms12010054  0.599
2023 Saul S, Karim M, Ghita L, Huang PT, Chiu W, Durán V, Lo CW, Kumar S, Bhalla N, Leyssen P, Alem F, Boghdeh NA, Tran DH, Cohen CA, Brown JA, et al. Anticancer pan-ErbB inhibitors reduce inflammation and tissue injury and exert broad-spectrum antiviral effects. The Journal of Clinical Investigation. PMID 37581931 DOI: 10.1172/JCI169510  0.43
2023 Anderson C, Baha H, Boghdeh N, Barrera M, Alem F, Narayanan A. Interactions of Equine Viruses with the Host Kinase Machinery and Implications for One Health and Human Disease. Viruses. 15. PMID 37243249 DOI: 10.3390/v15051163  0.548
2023 Boghdeh NA, McGraw B, Barrera MD, Anderson C, Baha H, Risner KH, Ogungbe IV, Alem F, Narayanan A. Inhibitors of the Ubiquitin-Mediated Signaling Pathway Exhibit Broad-Spectrum Antiviral Activities against New World Alphaviruses. Viruses. 15. PMID 36992362 DOI: 10.3390/v15030655  0.459
2022 Boghdeh NA, Risner KH, Barrera MD, Britt CM, Schaffer DK, Alem F, Brown JA, Wikswo JP, Narayanan A. Application of a Human Blood Brain Barrier Organ-on-a-Chip Model to Evaluate Small Molecule Effectiveness against Venezuelan Equine Encephalitis Virus. Viruses. 14. PMID 36560802 DOI: 10.3390/v14122799  0.471
2022 Haikerwal A, Barrera MD, Bhalla N, Zhou W, Boghdeh N, Anderson C, Alem F, Narayanan A. Inhibition of Venezuelan Equine Encephalitis Virus Using Small Interfering RNAs. Viruses. 14. PMID 35893693 DOI: 10.3390/v14081628  0.653
2022 Hetrick B, Chilin LD, He S, Dabbagh D, Alem F, Narayanan A, Luchini A, Li T, Liu X, Copeland J, Pak A, Cunningham T, Liotta L, Petricoin EF, Andalibi A, et al. Development of a hybrid alphavirus-SARS-CoV-2 pseudovirion for rapid quantification of neutralization antibodies and antiviral drugs. Cell Reports Methods. 100181. PMID 35229082 DOI: 10.1016/j.crmeth.2022.100181  0.368
2021 Alem F, Olanrewaju AA, Omole S, Hobbs HE, Ahsan N, Matulis G, Brantner CA, Zhou W, Petricoin EF, Liotta LA, Caputi M, Bavari S, Wu Y, Kashanchi F, Hakami RM. Exosomes originating from infection with the cytoplasmic single-stranded RNA virus Rift Valley fever virus (RVFV) protect recipient cells by inducing RIG-I mediated IFN-B response that leads to activation of autophagy. Cell & Bioscience. 11: 220. PMID 34953502 DOI: 10.1186/s13578-021-00732-z  0.37
2021 Bakovic A, Bhalla N, Alem F, Campbell C, Zhou W, Narayanan A. Inhibitors of Venezuelan Equine Encephalitis Virus Identified Based on Host Interaction Partners of Viral Non-Structural Protein 3. Viruses. 13. PMID 34452398 DOI: 10.3390/v13081533  0.573
2021 Pinto DO, Al Sharif S, Mensah G, Cowen M, Khatkar P, Erickson J, Branscome H, Lattanze T, DeMarino C, Alem F, Magni R, Zhou W, Alais S, Dutartre H, El-Hage N, et al. Extracellular vesicles from HTLV-1 infected cells modulate target cells and viral spread. Retrovirology. 18: 6. PMID 33622348 DOI: 10.1186/s12977-021-00550-8  0.405
2021 Bakovic A, Risner K, Bhalla N, Alem F, Chang TL, Weston WK, Harness JA, Narayanan A. Brilacidin Demonstrates Inhibition of SARS-CoV-2 in Cell Culture. Viruses. 13. PMID 33572467 DOI: 10.3390/v13020271  0.358
2020 Dailey A, Saha J, Zaidi F, Abdirahman H, Haymond A, Alem F, Hakami R, Couch R. VOC fingerprints: metabolomic signatures of biothreat agents with and without antibiotic resistance. Scientific Reports. 10: 11746. PMID 32678173 DOI: 10.1038/s41598-020-68622-x  0.702
2018 Etobayeva I, Linden SB, Alem F, Harb L, Rizkalla L, Mosier PD, Johnson AA, Temple L, Hakami RM, Nelson DC. Discovery and Biochemical Characterization of PlyP56, PlyN74, and PlyTB40- Specific Endolysins. Viruses. 10. PMID 29883383 DOI: 10.3390/V10050276  0.662
2016 Chung MC, Alem F, Hamer SG, Narayanan A, Shatalin K, Bailey C, Nudler E, Hakami RM. S-nitrosylation of peroxiredoxin 1 contributes to viability of lung epithelial cells during Bacillus anthracis infection. Biochimica Et Biophysica Acta. PMID 27612662 DOI: 10.1016/J.Bbagen.2016.09.006  0.749
2015 Chiang CY, Uzoma I, Lane DJ, Memišević V, Alem F, Yao K, Kota KP, Bavari S, Wallqvist A, Hakami RM, Panchal RG. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Frontiers in Microbiology. 6: 683. PMID 26284031 DOI: 10.3389/Fmicb.2015.00683  0.75
2015 Alem F, Yao K, Lane D, Calvert V, Petricoin EF, Kramer L, Hale ML, Bavari S, Panchal RG, Hakami RM. Host response during Yersinia pestis infection of human bronchial epithelial cells involves negative regulation of autophagy and suggests a modulation of survival-related and cellular growth pathways. Frontiers in Microbiology. 6: 50. PMID 25762983 DOI: 10.3389/fmicb.2015.00050  0.774
2009 Crawford MA, Zhu Y, Green CS, Burdick MD, Sanz P, Alem F, O'Brien AD, Mehrad B, Strieter RM, Hughes MA. Antimicrobial effects of interferon-inducible CXC chemokines against Bacillus anthracis spores and bacilli. Infection and Immunity. 77: 1664-78. PMID 19179419 DOI: 10.1128/IAI.01208-08  0.346
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