| Year |
Citation |
Score |
| 2025 |
Chen L, Lin Y, Ding S, Huang M, Jiang L. Recent Advances in Clinically Used and Trialed Photosensitizers for Antitumor Photodynamic Therapy. Molecular Pharmaceutics. PMID 40437912 DOI: 10.1021/acs.molpharmaceut.5c00110 |
0.403 |
|
| 2025 |
Mai Y, Zhou Y, Ye Q, Wang Z, Li C, Chen Y, Xiao H, Hu Y, Li J, Zhang W, Wang T, Lin H, Jiang L, Yuan C, Xu P, et al. Bacteria-responsive antimicrobial and hemostatic cellulose-based dressing for wound treatments. International Journal of Biological Macromolecules. 144272. PMID 40381766 DOI: 10.1016/j.ijbiomac.2025.144272 |
0.36 |
|
| 2025 |
Zhou Y, Wang D, Wu J, Qi Y, Song M, Yao H, Liao CK, Lin H, Huang M, Zhuo D, Jiang L, Yuan C, Chen Y, Huang M, Li J, et al. Discovery of the Low-Hemorrhagic Antithrombotic Effect of Montelukast by Targeting FXIa in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 40013360 DOI: 10.1161/ATVBAHA.124.322145 |
0.397 |
|
| 2025 |
Jiang L, Yuan C, Flaumenhaft R, Huang M. Recent advances in vascular thiol isomerases: insights into structures, functions in thrombosis and antithrombotic inhibitor development. Thrombosis Journal. 23: 16. PMID 39962537 DOI: 10.1186/s12959-025-00699-8 |
0.436 |
|
| 2025 |
Li H, Qu Y, Guo Z, Chen D, Jiang L, Xu P, Huang M, Yuan C. Dual modified ferritin nanocages for tumor-targeted and microenvironment-responsive drug delivery. International Journal of Biological Macromolecules. 140694. PMID 39914543 DOI: 10.1016/j.ijbiomac.2025.140694 |
0.41 |
|
| 2025 |
Wang R, Li H, Xie Z, Huang M, Xu P, Yuan C, Li J, Flaumenhaft R, Huang M, Jiang L. Development of a recombinant Ang1 variant with enhanced Tie2 binding and its application to attenuate sepsis in mice. Science Advances. 11: eads1796. PMID 39813336 DOI: 10.1126/sciadv.ads1796 |
0.43 |
|
| 2025 |
Chen L, Li L, Zhao H, Li H, Li J, Li C, Zhou Y, Yang L, Liang J, Zhang H, Li J, Xu P, Yuan C, Liu Z, Huang M, ... Jiang L, et al. Integration of EMAP-II-targeted anti-angiogenesis and photodynamic therapy using zinc phthalocyanine nanosystem for enhanced cancer treatment. Colloids and Surfaces. B, Biointerfaces. 248: 114493. PMID 39778222 DOI: 10.1016/j.colsurfb.2024.114493 |
0.417 |
|
| 2024 |
Li J, Wang G, Mai Y, Zhang W, Zhao H, Zhou Y, Chen L, Lin Y, Jiang L, Xu P, Zhou X, Yuan C, Huang M. Lysosome-localization and tumor-targeting of novel photosensitizers enhance the ablation of cancer. Journal of Photochemistry and Photobiology. B, Biology. 261: 113045. PMID 39532016 DOI: 10.1016/j.jphotobiol.2024.113045 |
0.404 |
|
| 2024 |
Lin H, Xu M, Jiang L, Yuan C, Jiang C, Huang M, Li J, Xu P. Water-medicated specifically targeting the S1 pockets among serine proteases using an arginine analogue. Bioorganic Chemistry. 152: 107734. PMID 39167871 DOI: 10.1016/j.bioorg.2024.107734 |
0.44 |
|
| 2024 |
Li H, Wang R, Xu P, Yuan C, Huang M, Jiang L. Elucidating the molecular basis of PECAM-1 and Tie2 interaction from binding dynamics and complex formation. Biochemical and Biophysical Research Communications. 735: 150484. PMID 39094232 DOI: 10.1016/j.bbrc.2024.150484 |
0.375 |
|
| 2024 |
Yan W, Li H, Ning J, Huang S, Jiang L, Xu P, Huang M, Yuan C. Engineered protein cages with enhanced extracellular drug release for elevated antitumor efficacy. International Journal of Biological Macromolecules. 131492. PMID 38604418 DOI: 10.1016/j.ijbiomac.2024.131492 |
0.391 |
|
| 2024 |
Chen S, Fang S, Zhou Y, Huang Z, Yu S, Chen D, Wang Z, Xu Y, Liu P, Li Y, Lin W, Jiang L, Yuan C, Huang M. A low bleeding risk thrombolytic agent: citPA5. Cardiovascular Research. PMID 38546342 DOI: 10.1093/cvr/cvae060 |
0.342 |
|
| 2023 |
Xie S, Yang G, Wu J, Jiang L, Yuan C, Xu P, Huang M, Liu Y, Li J. screening of natural products as uPAR inhibitors via multiple structure-based docking and molecular dynamics simulations. Journal of Biomolecular Structure & Dynamics. 1-12. PMID 38111151 DOI: 10.1080/07391102.2023.2295386 |
0.475 |
|
| 2023 |
Xu Y, Hu Y, Wu G, Niu L, Fang C, Li Y, Jiang L, Yuan C, Huang M. Specific inhibition on PAI-1 reduces the dose of Alteplase for ischemic stroke treatment. International Journal of Biological Macromolecules. 257: 128618. PMID 38070813 DOI: 10.1016/j.ijbiomac.2023.128618 |
0.418 |
|
| 2023 |
Zhao H, Huang M, Jiang L. Potential Roles and Future Perspectives of Chitinase 3-like 1 in Macrophage Polarization and the Development of Diseases. International Journal of Molecular Sciences. 24. PMID 38003338 DOI: 10.3390/ijms242216149 |
0.379 |
|
| 2023 |
Wang Y, Luo Z, Morelli X, Xu P, Jiang L, Shi X, Huang M. Crystal Structures of Human Serum Albumin in Complex with Lysophosphatidylcholine. Biophysical Journal. PMID 37731243 DOI: 10.1016/j.bpj.2023.09.007 |
0.422 |
|
| 2023 |
Mai Y, Wang Z, Zhou Y, Wang G, Chen J, Lin Y, Ji P, Zhang W, Jing Q, Chen L, Chen Z, Lin H, Jiang L, Yuan C, Xu P, et al. From disinfectants to antibiotics: Enhanced biosafety of quaternary ammonium compounds by chemical modification. Journal of Hazardous Materials. 460: 132454. PMID 37703742 DOI: 10.1016/j.jhazmat.2023.132454 |
0.434 |
|
| 2023 |
Liu D, Jiang L, Chen J, Chen Z, Yuan C, Lin D, Huang M. Monomer and Oligomer Transition of Zinc Phthalocyanine Is Key for Photobleaching in Photodynamic Therapy. Molecules (Basel, Switzerland). 28. PMID 37375194 DOI: 10.3390/molecules28124639 |
0.365 |
|
| 2023 |
Xu Y, Chen D, Liu P, Hu Y, Peng S, Chen S, Li Y, Lin W, Jiang L, Yuan C, Huang M. A triple fusion tissue-type plasminogen activator (TriF-ΔtPA) enhanced thrombolysis in carotid embolism-induced stroke model. International Journal of Pharmaceutics. 122878. PMID 36958614 DOI: 10.1016/j.ijpharm.2023.122878 |
0.436 |
|
| 2023 |
Zhou Y, Song M, Xie D, Yan S, Yu S, Xie S, Cai M, Li H, Shang L, Jiang L, Yuan C, Huang M, Li J, Xu P. Structural Dynamics-Driven Discovery of Anticancer and Antimetastatic Effects of Diltiazem and Glibenclamide Targeting Urokinase Receptor. Journal of Medicinal Chemistry. PMID 36854648 DOI: 10.1021/acs.jmedchem.2c01663 |
0.438 |
|
| 2023 |
Li H, Wang Z, Yu S, Chen S, Zhou Y, Qu Y, Xu P, Jiang L, Yuan C, Huang M. Albumin-based drug carrier targeting urokinase receptor for cancer therapy. International Journal of Pharmaceutics. 122636. PMID 36696930 DOI: 10.1016/j.ijpharm.2023.122636 |
0.434 |
|
| 2022 |
Zhou Y, Yu S, Chen D, Li H, Xu P, Yuan C, Jiang L, Huang M. Nafamostat Mesylate in Combination with the Mouse Amino-Terminal Fragment of Urokinase-Human Serum Albumin Improves the Treatment Outcome of Triple-Negative Breast Cancer Therapy. Molecular Pharmaceutics. PMID 36463525 DOI: 10.1021/acs.molpharmaceut.2c00297 |
0.451 |
|
| 2022 |
Wang G, Yang L, Jiang L, Chen J, Jing Q, Mai Y, Deng L, Lin Y, Chen L, Chen Z, Xu P, Jiang L, Yuan C, Huang M. A new class of quaternary ammonium compounds as potent and environmental friendly disinfectants. Journal of Cleaner Production. 134632. PMID 36246409 DOI: 10.1016/j.jclepro.2022.134632 |
0.37 |
|
| 2022 |
Lin Y, Chen J, Mai Y, Chen L, Chen Z, Wang G, Deng L, Xu P, Yuan C, Jiang L, Huang M. Double-Grafted PET Fiber Material to Remove Airborne Bacteria with High Efficiency. Acs Applied Materials & Interfaces. PMID 36214495 DOI: 10.1021/acsami.2c13358 |
0.312 |
|
| 2022 |
Zhou Y, Wu J, Xue G, Li J, Jiang L, Huang M. Structural study of the uPA-nafamostat complex reveals a covalent inhibitory mechanism of nafamostat. Biophysical Journal. PMID 36039386 DOI: 10.1016/j.bpj.2022.08.034 |
0.433 |
|
| 2022 |
Chen J, Jing Q, Xu Y, Lin Y, Mai Y, Chen L, Wang G, Chen Z, Deng L, Chen J, Yuan C, Jiang L, Xu P, Huang M. Functionalized zinc oxide microparticles for improving the antimicrobial effects of skin-care products and wound-care medicines. Biomaterials Advances. 135: 212728. PMID 35929206 DOI: 10.1016/j.bioadv.2022.212728 |
0.363 |
|
| 2022 |
Chen S, Yuan C, Jiang L, Luo Z, Huang M. Crystallographic analysis of interaction between cisplatin and human serum albumin: Effect of fatty acid. International Journal of Biological Macromolecules. 216: 172-178. PMID 35788007 DOI: 10.1016/j.ijbiomac.2022.06.181 |
0.381 |
|
| 2022 |
Wang R, Yang M, Jiang L, Huang M. Role of Angiopoietin-Tie axis in vascular and lymphatic systems and therapeutic interventions. Pharmacological Research. 106331. PMID 35772646 DOI: 10.1016/j.phrs.2022.106331 |
0.376 |
|
| 2022 |
Chen D, Liu Y, Liu P, Zhou Y, Jiang L, Yuan C, Huang M. Orally delivered rutin in lipid-based nano-formulation exerts strong antithrombotic effects by protein disulfide isomerase inhibition. Drug Delivery. 29: 1824-1835. PMID 35674505 DOI: 10.1080/10717544.2022.2083726 |
0.447 |
|
| 2022 |
Yu S, Sui Y, Wang J, Li Y, Li H, Cao Y, Chen L, Jiang L, Yuan C, Huang M. Crystal structure and cellular functions of uPAR dimer. Nature Communications. 13: 1665. PMID 35351875 DOI: 10.1038/s41467-022-29344-y |
0.426 |
|
| 2022 |
Chen D, Liu P, Liu Y, Wang Z, Zhou Y, Jiang L, Yuan C, Li Y, Lin W, Huang M. A Clot-homing Near-infrared Probe for in vivo Imaging of Murine Thromboembolic Models. Advanced Healthcare Materials. e2102213. PMID 34994110 DOI: 10.1002/adhm.202102213 |
0.346 |
|
| 2021 |
S El Salamouni N, Buckley BJ, Jiang L, Huang M, Ranson M, Kelso MJ, Yu H. Disruption of Water Networks is the Cause of Human/Mouse Species Selectivity in Urokinase Plasminogen Activator (uPA) Inhibitors Derived from Hexamethylene Amiloride (HMA). Journal of Medicinal Chemistry. PMID 34898192 DOI: 10.1021/acs.jmedchem.1c01423 |
0.423 |
|
| 2021 |
Wang R, Huang M, Xu Y, Yuan C, Huang M, Jiang L. [Advances of Angiopoietin-Tie axis in vascular and lymphatic system-related diseases]. Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology. 37: 2633-2644. PMID 34472284 DOI: 10.13345/j.cjb.200522 |
0.357 |
|
| 2021 |
Yu S, Sun G, Sui Y, Li H, Mai Y, Wang G, Zhang N, Bi Y, Gao GF, Xu P, Jiang L, Yuan C, Yang Y, Huang M. Potent inhibition of Severe Acute Respiratory Syndrome Coronavirus 2 by photosensitizers compounds. Dyes and Pigments : An International Journal. 194: 109570. PMID 34183871 DOI: 10.1016/j.dyepig.2021.109570 |
0.363 |
|
| 2021 |
Sun G, Sui Y, Zhou Y, Ya J, Yuan C, Jiang L, Huang M. Structural basis of covalent inhibitory mechanism of TMPRSS2-related serine proteases by camostat. Journal of Virology. JVI0086121. PMID 34160253 DOI: 10.1128/JVI.00861-21 |
0.495 |
|
| 2021 |
Zhang D, Chen J, Jing Q, Chen Z, Ullah A, Jiang L, Zheng K, Yuan C, Huang M. Development of a Potent Antimicrobial Peptide With Photodynamic Activity. Frontiers in Microbiology. 12: 624465. PMID 34140932 DOI: 10.3389/fmicb.2021.624465 |
0.398 |
|
| 2021 |
Sun G, Yang M, Jiang L, Huang M. Regulation of pro-σ activation: a key checkpoint in Bacillus subtilis sporulation. Environmental Microbiology. PMID 33538382 DOI: 10.1111/1462-2920.15415 |
0.375 |
|
| 2021 |
Yuan C, Guo Z, Yu S, Jiang L, Huang M. Development of inhibitors for uPAR: blocking the interaction of uPAR with its partners. Drug Discovery Today. PMID 33486111 DOI: 10.1016/j.drudis.2021.01.016 |
0.433 |
|
| 2021 |
Jiang L, Yuan C, Huang M. A general strategy to inhibit serine protease by targeting its autolysis loop. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21259. PMID 33417271 DOI: 10.1096/fj.202002139RR |
0.473 |
|
| 2020 |
Zhou Y, Chen D, Xue G, Yu S, Yuan C, Huang M, Jiang L. Improved therapeutic efficacy of quercetin-loaded polymeric nanoparticles on triple-negative breast cancer by inhibiting uPA. Rsc Advances. 10: 34517-34526. PMID 35514369 DOI: 10.1039/d0ra04231e |
0.391 |
|
| 2020 |
Huang M, Li L, Shen J, Wang Y, Wang R, Yuan C, Huang M, Jiang L. Plasma levels of the active form of suPAR are associated with COVID-19 severity. Critical Care (London, England). 24: 704. PMID 33372603 DOI: 10.1186/s13054-020-03336-0 |
0.328 |
|
| 2020 |
Li L, Huang M, Shen J, Wang Y, Wang R, Yuan C, Jiang L, Huang M. Serum Levels of Soluble Platelet Endothelial Cell Adhesion Molecule 1 in COVID-19 Patients Are Associated With Disease Severity. The Journal of Infectious Diseases. PMID 33179035 DOI: 10.1093/infdis/jiaa642 |
0.34 |
|
| 2020 |
Xu Y, Chen S, Chen D, Peng S, Cheng Y, Li J, Li Y, Jiang L, Yuan C, Huang M. [Recent progress in developing of thrombolytic agents for ischemic stroke]. Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology. 36: 2029-2039. PMID 33169568 DOI: 10.13345/j.cjb.200107 |
0.361 |
|
| 2020 |
Jiang Y, Lin L, Chen S, Jiang L, Kriegbaum MC, Gårdsvoll H, Hansen LV, Li J, Ploug M, Yuan C, Huang M. Crystal Structures of Human C4.4A Reveal the Unique Association of Ly6/uPAR/α-neurotoxin Domain. International Journal of Biological Sciences. 16: 981-993. PMID 32140067 DOI: 10.7150/ijbs.39919 |
0.451 |
|
| 2020 |
Xue G, Xie X, Zhou Y, Yuan C, Huang M, Jiang L. Insight to the residue in P2 position prevents the peptide inhibitor from being hydrolyzed by serine proteases. Bioscience, Biotechnology, and Biochemistry. 1-7. PMID 32019421 DOI: 10.1080/09168451.2020.1723405 |
0.467 |
|
| 2020 |
Li L, Chen D, Zheng K, Jiang L, Dai T, Yang L, Jiang L, Chen Z, Yuan C, Huang M. Enhanced antitumor efficacy and imaging application of photosensitizer-formulated Paclitaxel. Acs Applied Materials & Interfaces. PMID 31909969 DOI: 10.1021/acsami.9b18396 |
0.403 |
|
| 2019 |
Buckley BJ, Majed H, Aboelela A, Minaei E, Jiang L, Fildes K, Cheung CY, Johnson D, Bachovchin D, Cook GM, Huang M, Ranson M, Kelso MJ. 6-Substituted amiloride derivatives as inhibitors of the urokinase-type plasminogen activator for use in metastatic disease. Bioorganic & Medicinal Chemistry Letters. 126753. PMID 31679971 DOI: 10.1016/j.bmcl.2019.126753 |
0.454 |
|
| 2019 |
Zuo K, Qi Y, Yuan C, Jiang L, Xu P, Hu J, Huang M, Li J. Specifically targeting cancer proliferation and metastasis processes: the development of matriptase inhibitors. Cancer Metastasis Reviews. PMID 31471691 DOI: 10.1007/s10555-019-09802-8 |
0.478 |
|
| 2019 |
Jiang L, Xie X, Li J, Persson E, Huang M. Crystal structure, epitope, and functional impact of an antibody against a superactive FVIIa provide insights into allosteric mechanism. Research and Practice in Thrombosis and Haemostasis. 3: 412-419. PMID 31294329 DOI: 10.1002/rth2.12211 |
0.433 |
|
| 2019 |
Xie X, Guo N, Xue G, Xie D, Yuan C, Harrison J, Li J, Jiang L, Huang M. Solution Structure of SpoIVB Reveals Mechanism of PDZ Domain-Regulated Protease Activity. Frontiers in Microbiology. 10: 1232. PMID 31244791 DOI: 10.3389/fmicb.2019.01232 |
0.444 |
|
| 2019 |
Liu M, Lin L, Hansen GH, Ploug M, Hanlin L, Jiang L, Yuan C, Li J, Huang M. Crystal structure of the unoccupied murine urokinase-type plasminogen activator receptor (uPAR) reveals a tightly packed DII-DIII unit. Febs Letters. PMID 31044429 DOI: 10.1002/1873-3468.13397 |
0.508 |
|
| 2019 |
Li R, Liang C, Jiang L, Yuan C, Huang M. Structural determination of group A Streptococcal surface dehydrogenase and characterization of its interaction with urokinase-type plasminogen activator receptor. Biochemical and Biophysical Research Communications. PMID 30737033 DOI: 10.1016/j.bbrc.2019.01.102 |
0.404 |
|
| 2019 |
Wang D, Yang Y, Jiang LX, Wang Y, Li J, Andreasen PA, Chen Z, Huang M, Xu P. Suppression of Tumor Growth and Metastases by Targeted Intervention in Urokinase Activity with Cyclic Peptides. Journal of Medicinal Chemistry. PMID 30707839 DOI: 10.1021/Acs.Jmedchem.8B01908 |
0.453 |
|
| 2018 |
Jiang L, Zhang X, Zhou Y, Chen Y, Luo Z, Li J, Yuan C, Huang M. Halogen bonding for the design of inhibitors by targeting the S1 pocket of serine proteases. Rsc Advances. 8: 28189-28197. PMID 35542712 DOI: 10.1039/c8ra03145b |
0.468 |
|
| 2018 |
Lin H, Chen J, Zhang Y, Ulla A, Liu J, Lin F, Jiang L, Huang M. Enhanced anti-microbial effect through cationization of a mono-triazatricyclodecane substituted asymmetric phthalocyanine. Journal of Inorganic Biochemistry. 189: 192-198. PMID 30317065 DOI: 10.1016/j.jinorgbio.2018.10.001 |
0.371 |
|
| 2018 |
Buckley BJ, Aboelela A, Minaei E, Jiang L, Xu Z, Ali U, Fildes K, Cheung CY, Cook SM, Johnson D, Bachovchin DA, Cook GM, Apte M, Huang M, Ranson M, et al. 6-Substituted hexamethylene amiloride (HMA) derivatives as potent and selective inhibitors of the human urokinase plasminogen activator for use in cancer. Journal of Medicinal Chemistry. PMID 30130401 DOI: 10.1021/acs.jmedchem.8b00838 |
0.446 |
|
| 2018 |
Xu M, Chen Y, Xu P, Andreasen PA, Jiang L, Li J, Huang M. Crystal Structure of Plasma Kallikrein Provides Insights into the Unusual Flexibility of the S1 Pocket Triggered by Glu217. Febs Letters. PMID 30019481 DOI: 10.1002/1873-3468.13191 |
0.473 |
|
| 2018 |
Jiang L, Oldenburg E, Kromann-Hansen T, Xu P, Jensen JK, Andreasen PA, Huang M. Cleavage of peptidic inhibitors by target protease is caused by peptide conformational transition. Biochimica Et Biophysica Acta. PMID 29959058 DOI: 10.1016/j.bbagen.2018.06.016 |
0.442 |
|
| 2018 |
Li R, Ma H, Jiang L, Qiao S, Zhi Y, Huang M, Deng R, Zhang G. The CD163 long-range scavenger receptor cysteine-rich repeat: expression, purification and X-ray crystallographic characterization. Acta Crystallographica. Section F, Structural Biology Communications. 74: 322-326. PMID 29718001 DOI: 10.1107/S2053230X18005551 |
0.366 |
|
| 2018 |
Li S, Li L, Chen Z, Xue G, Jiang L, Zheng K, Chen J, Li R, Yuan C, Huang M. A novel purification procedure for recombinant human serum albumin expressed in pichia pastoris. Protein Expression and Purification. PMID 29678737 DOI: 10.1016/j.pep.2018.04.012 |
0.384 |
|
| 2018 |
Jia Y, Li J, Chen J, Hu P, Jiang L, Chen X, Huang M, Chen Z, Xu P. A Smart Photosensitizer: Tumor-triggered Oncotherapy by Self-Assembly Photodynamic Nanodots. Acs Applied Materials & Interfaces. PMID 29652473 DOI: 10.1021/acsami.7b19058 |
0.397 |
|
| 2017 |
Xue G, Gong L, Yuan C, Xu M, Wang X, Jiang L, Huang M. A structural mechanism of flavonoids in inhibiting serine proteases. Food & Function. PMID 28644504 DOI: 10.1039/c6fo01825d |
0.482 |
|
| 2017 |
Liu M, Yuan C, Jensen J, Zhao B, Jiang Y, Jiang L, Huang M. The Crystal Structure of a Membrane-bound Multi-domain Protease Inhibitor Reveals the Mechanism of Its Auto-inhibition. The Journal of Biological Chemistry. PMID 28348076 DOI: 10.1074/jbc.M117.779256 |
0.484 |
|
| 2017 |
Liu M, Yuan C, Jiang Y, Jiang L, Huang M. Recombinant hepatocyte growth factor activator inhibitor 1: expression in Drosophila S2 cells, purification and crystallization. Acta Crystallographica. Section F, Structural Biology Communications. 73: 45-50. PMID 28045393 DOI: 10.1107/S2053230X16020082 |
0.434 |
|
| 2016 |
Ma H, Jiang L, Qiao S, Zhi Y, Chen XX, Yang Y, Huang X, Huang M, Li R, Zhang GP. Crystal Structure of the Fifth Scavenger Receptor Cysteine-Rich Domain (SRCR5) from Porcine CD163 Reveals an Important Residue Involved in Porcine Reproductive and Respiratory Syndrome Virus Infection. Journal of Virology. PMID 27881657 DOI: 10.1128/JVI.01897-16 |
0.4 |
|
| 2016 |
Jiang L, Lin L, Li R, Yuan C, Xu M, Huang JH, Huang M. Dimer conformation of soluble PECAM-1, an endothelial marker. The International Journal of Biochemistry & Cell Biology. PMID 27270333 DOI: 10.1016/j.biocel.2016.06.001 |
0.495 |
|
| 2016 |
Yuan C, Jürgensen HJ, Engelholm LH, Li R, Liu M, Jiang L, Luo Z, Behrendt N, Huang M. Crystal structures of the ligand binding region of uPARAP: effect of calcium ion binding. The Biochemical Journal. PMID 27247422 DOI: 10.1042/BCJ20160276 |
0.405 |
|
| 2015 |
Jiang L, Andersen LM, Andreasen PA, Chen L, Huang M. Insights into the serine protease mechanism based on structural observations of the conversion of a peptidyl serine protease inhibitor to a substrate. Biochimica Et Biophysica Acta. PMID 26691138 DOI: 10.1016/J.Bbagen.2015.12.009 |
0.442 |
|
| 2015 |
Xu P, Xu M, Jiang L, Yang Q, Luo Z, Dauter Z, Huang M, Andreasen PA. Design of Specific Serine Protease Inhibitors Based on a Versatile Peptide Scaffold: Conversion of a Urokinase Inhibitor to a Plasma Kallikrein Inhibitor. Journal of Medicinal Chemistry. PMID 26536069 DOI: 10.1021/acs.jmedchem.5b01128 |
0.472 |
|
| 2015 |
Sørensen HP, Xu P, Jiang L, Kromann-Hansen T, Jensen KJ, Huang M, Andreasen PA. Selection of High Affinity Peptidic Serine Protease Inhibitors with Increased Binding Entropy from a Back-Flip Library of Peptide-Protein Fusions. Journal of Molecular Biology. PMID 26281711 DOI: 10.1016/j.jmb.2015.08.005 |
0.453 |
|
| 2015 |
Jiang L, Zhao B, Xu P, Sørensen HP, Jensen JK, Christensen A, Hosseini M, Nielsen NC, Jensen KJ, Andreasen PA, Huang M. Distinctive binding modes and inhibitory mechanisms of two peptidic inhibitors of urokinase-type plasminogen activator with isomeric P1 residues. The International Journal of Biochemistry & Cell Biology. 62: 88-92. PMID 25744057 DOI: 10.1016/j.biocel.2015.02.016 |
0.456 |
|
| 2014 |
Zhao B, Xu P, Jiang L, Paaske B, Kromann-Hansen T, Jensen JK, Sørensen HP, Liu Z, Nielsen JT, Christensen A, Hosseini M, Sørensen KK, Nielsen NC, Jensen KJ, Huang M, et al. A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility. Plos One. 9: e115872. PMID 25545505 DOI: 10.1371/journal.pone.0115872 |
0.467 |
|
| 2013 |
Roodbeen R, Paaske B, Jiang L, Jensen JK, Christensen A, Nielsen JT, Huang M, Mulder FA, Nielsen NC, Andreasen PA, Jensen KJ. Bicyclic peptide inhibitor of urokinase-type plasminogen activator: mode of action. Chembiochem : a European Journal of Chemical Biology. 14: 2179-88. PMID 24115455 DOI: 10.1002/Cbic.201300335 |
0.424 |
|
| 2013 |
Jiang L, Botkjaer KA, Andersen LM, Yuan C, Andreasen PA, Huang M. Rezymogenation of active urokinase induced by an inhibitory antibody. The Biochemical Journal. 449: 161-6. PMID 23016918 DOI: 10.1042/BJ20121132 |
0.446 |
|
| 2011 |
Jiang L, Svane AS, Sørensen HP, Jensen JK, Hosseini M, Chen Z, Weydert C, Nielsen JT, Christensen A, Yuan C, Jensen KJ, Nielsen NC, Malmendal A, Huang M, Andreasen PA. The binding mechanism of a peptidic cyclic serine protease inhibitor. Journal of Molecular Biology. 412: 235-50. PMID 21802428 DOI: 10.1016/j.jmb.2011.07.028 |
0.474 |
|
| 2011 |
Hosseini M, Jiang L, Sørensen HP, Jensen JK, Christensen A, Fogh S, Yuan C, Andersen LM, Huang M, Andreasen PA, Jensen KJ. Elucidation of the contribution of active site and exosite interactions to affinity and specificity of peptidylic serine protease inhibitors using non-natural arginine analogs. Molecular Pharmacology. 80: 585-97. PMID 21719463 DOI: 10.1124/mol.111.072280 |
0.484 |
|
| 2011 |
Ngo JC, Jiang L, Lin Z, Yuan C, Chen Z, Zhang X, Yu H, Wang J, Lin L, Huang M. Structural basis for therapeutic intervention of uPA/uPAR system. Current Drug Targets. 12: 1729-43. PMID 21707478 |
0.552 |
|
| 2011 |
Lin Z, Jiang L, Yuan C, Jensen JK, Zhang X, Luo Z, Furie BC, Furie B, Andreasen PA, Huang M. Structural basis for recognition of urokinase-type plasminogen activator by plasminogen activator inhibitor-1. The Journal of Biological Chemistry. 286: 7027-32. PMID 21199867 DOI: 10.1074/Jbc.M110.204537 |
0.476 |
|
| 2010 |
Bian C, Yuan C, Chen L, Meehan EJ, Jiang L, Huang Z, Lin L, Huang M. Crystal structure of a triacylglycerol lipase from Penicillium expansum at 1.3 A determined by sulfur SAD. Proteins. 78: 1601-5. PMID 20146362 DOI: 10.1002/Prot.22676 |
0.462 |
|
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