| Year |
Citation |
Score |
| 2023 |
Hiramoto T, Inaba H, Baatartsogt N, Kashiwakura Y, Hayakawa M, Kamoshita N, Nishimasu H, Nureki O, Kinai E, Ohmori T. Genome editing of patient-derived iPSCs identifies a deep intronic variant causing aberrant splicing in hemophilia A. Blood Advances. 7: 7017-7027. PMID 37792826 DOI: 10.1182/bloodadvances.2023010838 |
0.586 |
|
| 2023 |
Mise-Omata S, Ando M, Srirat T, Nakagawara K, Hayakawa T, Iizuka-Koga M, Nishimasu H, Nureki O, Ito M, Yoshimura A. SOCS3 deletion in effector T cells confers an anti-tumorigenic role of IL-6 to the pro-tumorigenic cytokine. Cell Reports. 42: 112940. PMID 37582370 DOI: 10.1016/j.celrep.2023.112940 |
0.565 |
|
| 2023 |
Shibata K, Oda K, Nishizawa T, Hazama Y, Ono R, Takaramoto S, Bagherzadeh R, Yawo H, Nureki O, Inoue K, Akiyama H. Twisting and Protonation of Retinal Chromophore Regulate Channel Gating of Channelrhodopsin C1C2. Journal of the American Chemical Society. 145: 10779-10789. PMID 37129501 DOI: 10.1021/jacs.3c01879 |
0.62 |
|
| 2023 |
Hiramoto T, Kashiwakura Y, Hayakawa M, Baatartsogt N, Kamoshita N, Abe T, Inaba H, Nishimasu H, Uosaki H, Hanazono Y, Nureki O, Ohmori T. PAM-flexible Cas9-mediated base editing of a hemophilia B mutation in induced pluripotent stem cells. Communications Medicine. 3: 56. PMID 37076593 DOI: 10.1038/s43856-023-00286-w |
0.57 |
|
| 2022 |
Futamata H, Fukuda M, Umeda R, Yamashita K, Tomita A, Takahashi S, Shikakura T, Hayashi S, Kusakizako T, Nishizawa T, Homma K, Nureki O. Author Correction: Cryo-EM structures of thermostabilized prestin provide mechanistic insights underlying outer hair cell electromotility. Nature Communications. 13: 7337. PMID 36443347 DOI: 10.1038/s41467-022-34985-0 |
0.628 |
|
| 2022 |
Futamata H, Fukuda M, Umeda R, Yamashita K, Tomita A, Takahashi S, Shikakura T, Hayashi S, Kusakizako T, Nishizawa T, Homma K, Nureki O. Cryo-EM structures of thermostabilized prestin provide mechanistic insights underlying outer hair cell electromotility. Nature Communications. 13: 6208. PMID 36266333 DOI: 10.1038/s41467-022-34017-x |
0.672 |
|
| 2022 |
Nakagawa R, Kannan S, Altae-Tran H, Takeda SN, Tomita A, Hirano H, Kusakizako T, Nishizawa T, Yamashita K, Zhang F, Nishimasu H, Nureki O. Structure and engineering of the minimal type VI CRISPR-Cas13bt3. Molecular Cell. 82: 3178-3192.e5. PMID 36027912 DOI: 10.1016/j.molcel.2022.08.001 |
0.75 |
|
| 2022 |
Kato T, Kusakizako T, Jin C, Zhou X, Ohgaki R, Quan L, Xu M, Okuda S, Kobayashi K, Yamashita K, Nishizawa T, Kanai Y, Nureki O. Structural insights into inhibitory mechanism of human excitatory amino acid transporter EAAT2. Nature Communications. 13: 4714. PMID 35953475 DOI: 10.1038/s41467-022-32442-6 |
0.641 |
|
| 2022 |
Kobayashi K, Kawakami K, Kusakizako T, Miyauchi H, Tomita A, Kobayashi K, Shihoya W, Yamashita K, Nishizawa T, Kato HE, Inoue A, Nureki O. Endogenous ligand recognition and structural transition of a human PTH receptor. Molecular Cell. PMID 35932760 DOI: 10.1016/j.molcel.2022.07.003 |
0.766 |
|
| 2022 |
Yamaguchi S, Naganuma M, Nishizawa T, Kusakizako T, Tomari Y, Nishimasu H, Nureki O. Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex. Nature. PMID 35768503 DOI: 10.1038/s41586-022-04790-2 |
0.758 |
|
| 2022 |
Kasuya G, Nureki O. Recent Advances in the Structural Biology of the Volume-Regulated Anion Channel LRRC8. Frontiers in Pharmacology. 13: 896532. PMID 35645818 DOI: 10.3389/fphar.2022.896532 |
0.306 |
|
| 2022 |
Shinoda H, Iida T, Makino A, Yoshimura M, Ishikawa J, Ando J, Murai K, Sugiyama K, Muramoto Y, Nakano M, Kiga K, Cui L, Nureki O, Takeuchi H, Noda T, et al. Automated amplification-free digital RNA detection platform for rapid and sensitive SARS-CoV-2 diagnosis. Communications Biology. 5: 473. PMID 35614128 DOI: 10.1038/s42003-022-03433-6 |
0.575 |
|
| 2022 |
Hagino T, Kato T, Kasuya G, Kobayashi K, Kusakizako T, Hamamoto S, Sobajima T, Fujiwara Y, Yamashita K, Kawasaki H, Maturana AD, Nishizawa T, Nureki O. Cryo-EM structures of thylakoid-located voltage-dependent chloride channel VCCN1. Nature Communications. 13: 2505. PMID 35523970 DOI: 10.1038/s41467-022-30292-w |
0.658 |
|
| 2022 |
Ma XF, Wang TT, Wang WH, Guan L, Guo CR, Li XH, Lei YT, Fan YZ, Yang XN, Hattori M, Nureki O, Zhu MX, Yu Y, Tian Y, Wang J. The long β2,3-sheets encoded by redundant sequences play an integral role in the channel function of P2X7 receptors. The Journal of Biological Chemistry. 102002. PMID 35504351 DOI: 10.1016/j.jbc.2022.102002 |
0.666 |
|
| 2022 |
Kurihara N, Nakagawa R, Hirano H, Okazaki S, Tomita A, Kobayashi K, Kusakizako T, Nishizawa T, Yamashita K, Scott DA, Nishimasu H, Nureki O. Structure of the type V-C CRISPR-Cas effector enzyme. Molecular Cell. PMID 35366394 DOI: 10.1016/j.molcel.2022.03.006 |
0.768 |
|
| 2022 |
Nakagawa R, Ishiguro S, Okazaki S, Mori H, Tanaka M, Aburatani H, Yachie N, Nishimasu H, Nureki O. Engineered Campylobacter jejuni Cas9 variant with enhanced activity and broader targeting range. Communications Biology. 5: 211. PMID 35260779 DOI: 10.1038/s42003-022-03149-7 |
0.602 |
|
| 2022 |
Kishi KE, Kim YS, Fukuda M, Inoue M, Kusakizako T, Wang PY, Ramakrishnan C, Byrne EFX, Thadhani E, Paggi JM, Matsui TE, Yamashita K, Nagata T, Konno M, Quirin S, ... ... Nureki O, et al. Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine. Cell. PMID 35114111 DOI: 10.1016/j.cell.2022.01.007 |
0.687 |
|
| 2021 |
Iriki H, Takahashi H, Wada N, Nomura H, Mukai M, Kamata A, Ito H, Yamagami J, Matsui T, Kurebayashi Y, Mise-Omata S, Nishimasu H, Nureki O, Yoshimura A, Hori S, et al. Peripheral tolerance by Treg via constraining OX40 signal in autoreactive T cells against desmoglein 3, a target antigen in pemphigus. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34848535 DOI: 10.1073/pnas.2026763118 |
0.568 |
|
| 2021 |
Tomita A, Daiho T, Kusakizako T, Yamashita K, Ogasawara S, Murata T, Nishizawa T, Nureki O. Cryo-EM reveals mechanistic insights into lipid-facilitated polyamine export by human ATP13A2. Molecular Cell. 81: 4799-4809.e5. PMID 34798056 DOI: 10.1016/j.molcel.2021.11.001 |
0.655 |
|
| 2021 |
Sato K, Kumar A, Hamada K, Okada C, Oguni A, Machiyama A, Sakuraba S, Nishizawa T, Nureki O, Kono H, Ogata K, Sengoku T. Structural basis of the regulation of the normal and oncogenic methylation of nucleosomal histone H3 Lys36 by NSD2. Nature Communications. 12: 6605. PMID 34782608 DOI: 10.1038/s41467-021-26913-5 |
0.618 |
|
| 2021 |
Kise Y, Kasuya G, Okamoto HH, Yamanouchi D, Kobayashi K, Kusakizako T, Nishizawa T, Nakajo K, Nureki O. Structural basis of gating modulation of Kv4 channel complexes. Nature. 599: 158-164. PMID 34552243 DOI: 10.1038/s41586-021-03935-z |
0.629 |
|
| 2021 |
Okamoto HH, Miyauchi H, Inoue A, Raimondi F, Tsujimoto H, Kusakizako T, Shihoya W, Yamashita K, Suno R, Nomura N, Kobayashi T, Iwata S, Nishizawa T, Nureki O. Cryo-EM structure of the human MT-G signaling complex. Nature Structural & Molecular Biology. PMID 34354246 DOI: 10.1038/s41594-021-00634-1 |
0.628 |
|
| 2021 |
Nagiri C, Kobayashi K, Tomita A, Kato M, Kobayashi K, Yamashita K, Nishizawa T, Inoue A, Shihoya W, Nureki O. Cryo-EM structure of the β3-adrenergic receptor reveals the molecular basis of subtype selectivity. Molecular Cell. PMID 34314699 DOI: 10.1016/j.molcel.2021.06.024 |
0.635 |
|
| 2021 |
Oura S, Noda T, Morimura N, Hitoshi S, Nishimasu H, Nagai Y, Nureki O, Ikawa M. Precise CAG repeat contraction in a Huntington's Disease mouse model is enabled by gene editing with SpCas9-NG. Communications Biology. 4: 771. PMID 34163001 DOI: 10.1038/s42003-021-02304-w |
0.576 |
|
| 2021 |
Jin F, Sun M, Fujii T, Yamada Y, Wang J, Maturana AD, Wada M, Su S, Ma J, Takeda H, Kusakizako T, Tomita A, Nakada-Nakura Y, Liu K, Uemura T, ... ... Nureki O, et al. The structure of MgtE in the absence of magnesium provides new insights into channel gating. Plos Biology. 19: e3001231. PMID 33905418 DOI: 10.1371/journal.pbio.3001231 |
0.692 |
|
| 2021 |
Shinoda H, Taguchi Y, Nakagawa R, Makino A, Okazaki S, Nakano M, Muramoto Y, Takahashi C, Takahashi I, Ando J, Noda T, Nureki O, Nishimasu H, Watanabe R. Amplification-free RNA detection with CRISPR-Cas13. Communications Biology. 4: 476. PMID 33875803 DOI: 10.1038/s42003-021-02001-8 |
0.575 |
|
| 2021 |
Castellano S, Claxton DP, Ficici E, Kusakizako T, Stix R, Zhou W, Nureki O, Mchaourab HS, Faraldo-Gómez JD. Conserved binding site in the N-lobe of prokaryotic MATE transporters suggests a role for Na in ion-coupled drug efflux. The Journal of Biological Chemistry. 296: 100262. PMID 33837745 DOI: 10.1016/j.jbc.2021.100262 |
0.349 |
|
| 2021 |
Oda K, Nomura T, Nakane T, Yamashita K, Inoue K, Ito S, Vierock J, Hirata K, Maturana AD, Katayama K, Ikuta T, Ishigami I, Izume T, Umeda R, Eguma R, ... ... Nureki O, et al. Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin. Elife. 10. PMID 33752801 DOI: 10.7554/eLife.62389 |
0.66 |
|
| 2021 |
Takeda H, Tsutsumi A, Nishizawa T, Lindau C, Busto JV, Wenz LS, Ellenrieder L, Imai K, Straub SP, Mossmann W, Qiu J, Yamamori Y, Tomii K, Suzuki J, Murata T, ... ... Nureki O, et al. Mitochondrial sorting and assembly machinery operates by β-barrel switching. Nature. PMID 33408415 DOI: 10.1038/s41586-020-03113-7 |
0.617 |
|
| 2021 |
Castellano S, Claxton DP, Ficici E, Kusakizako T, Stix R, Zhou W, Nureki O, Mchaourab HS, Faraldo-Gómez JD. Conserved binding site in the N-lobe of prokaryotic MATE transporters suggests a role for Na in ion-coupled drug efflux. The Journal of Biological Chemistry. PMID 33402425 DOI: 10.1074/jbc.RA120.016792 |
0.349 |
|
| 2020 |
Takeda SN, Nakagawa R, Okazaki S, Hirano H, Kobayashi K, Kusakizako T, Nishizawa T, Yamashita K, Nishimasu H, Nureki O. Structure of the miniature type V-F CRISPR-Cas effector enzyme. Molecular Cell. PMID 33333018 DOI: 10.1016/j.molcel.2020.11.035 |
0.726 |
|
| 2020 |
Oda K, Lee Y, Wiriyasermkul P, Tanaka Y, Takemoto M, Yamashita K, Nagamori S, Nishizawa T, Nureki O. Consensus mutagenesis approach improves the thermal stability of system x transporter, xCT, and enables cryo-EM analyses. Protein Science : a Publication of the Protein Society. PMID 33016372 DOI: 10.1002/pro.3966 |
0.663 |
|
| 2020 |
Nakanishi H, Nishizawa T, Segawa K, Nureki O, Fujiyoshi Y, Nagata S, Abe K. Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM. Cell Reports. 32: 108208. PMID 32997992 DOI: 10.1016/j.celrep.2020.108208 |
0.66 |
|
| 2020 |
Sakai R, Ito M, Komai K, Iizuka-Koga M, Matsuo K, Nakayama T, Yoshie O, Amano K, Nishimasu H, Nureki O, Kubo M, Yoshimura A. Kidney GATA3 regulatory T cells play roles in the convalescence stage after antibody-mediated renal injury. Cellular & Molecular Immunology. PMID 32917984 DOI: 10.1038/s41423-020-00547-x |
0.563 |
|
| 2020 |
Demura K, Kusakizako T, Shihoya W, Hiraizumi M, Nomura K, Shimada H, Yamashita K, Nishizawa T, Taruno A, Nureki O. Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies. Science Advances. 6: eaba8105. PMID 32832629 DOI: 10.1126/Sciadv.Aba8105 |
0.669 |
|
| 2020 |
Shimada H, Kusakizako T, Dung Nguyen TH, Nishizawa T, Hino T, Tominaga M, Nureki O. The structure of lipid nanodisc-reconstituted TRPV3 reveals the gating mechanism. Nature Structural & Molecular Biology. 27: 645-652. PMID 32572254 DOI: 10.1038/s41594-020-0439-z |
0.639 |
|
| 2020 |
Sakata RC, Ishiguro S, Mori H, Tanaka M, Tatsuno K, Ueda H, Yamamoto S, Seki M, Masuyama N, Nishida K, Nishimasu H, Arakawa K, Kondo A, Nureki O, Tomita M, et al. Publisher Correction: Base editors for simultaneous introduction of C-to-T and A-to-G mutations. Nature Biotechnology. PMID 32504047 DOI: 10.1038/S41587-020-0585-1 |
0.556 |
|
| 2020 |
Sakata RC, Ishiguro S, Mori H, Tanaka M, Tatsuno K, Ueda H, Yamamoto S, Seki M, Masuyama N, Nishida K, Nishimasu H, Arakawa K, Kondo A, Nureki O, Tomita M, et al. Base editors for simultaneous introduction of C-to-T and A-to-G mutations. Nature Biotechnology. PMID 32483365 DOI: 10.1038/S41587-020-0509-0 |
0.597 |
|
| 2020 |
Nakamura R, Numata T, Kasuya G, Yokoyama T, Nishizawa T, Kusakizako T, Kato T, Hagino T, Dohmae N, Inoue M, Watanabe K, Ichijo H, Kikkawa M, Shirouzu M, Jentsch TJ, ... ... Nureki O, et al. Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation. Communications Biology. 3: 240. PMID 32415200 DOI: 10.1038/s42003-020-0951-z |
0.707 |
|
| 2020 |
Umeda R, Satouh Y, Takemoto M, Nakada-Nakura Y, Liu K, Yokoyama T, Shirouzu M, Iwata S, Nomura N, Sato K, Ikawa M, Nishizawa T, Nureki O. Structural insights into tetraspanin CD9 function. Nature Communications. 11: 1606. PMID 32231207 DOI: 10.1038/S41467-020-15459-7 |
0.627 |
|
| 2020 |
Kobayashi K, Shihoya W, Nishizawa T, Kadji FMN, Aoki J, Inoue A, Nureki O. Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein. Nature Structural & Molecular Biology. 27: 274-280. PMID 32157248 DOI: 10.1038/s41594-020-0386-8 |
0.632 |
|
| 2020 |
Kawaguchi M, Okabe T, Okudaira S, Hama K, Kano K, Nishimasu H, Nakagawa H, Ishitani R, Kojima H, Nureki O, Aoki J, Nagano T. Identification of Potent Autotaxin Inhibitors that Bind to Both Hydrophobic Pockets and Channels in the Catalytic Domain. Journal of Medicinal Chemistry. PMID 32134652 DOI: 10.1021/Acs.Jmedchem.9B01967 |
0.63 |
|
| 2020 |
Yamaguchi S, Oe A, Nishida KM, Yamashita K, Kajiya A, Hirano S, Matsumoto N, Dohmae N, Ishitani R, Saito K, Siomi H, Nishimasu H, Siomi MC, Nureki O. Crystal structure of Drosophila Piwi. Nature Communications. 11: 858. PMID 32051406 DOI: 10.1038/s41467-020-14687-1 |
0.654 |
|
| 2020 |
Tanaka Y, Hipolito CJ, Maturana AD, Ito K, Kuroda T, Higuchi T, Katoh T, Kato HE, Hattori M, Kumazaki K, Tsukazaki T, Ishitani R, Suga H, Nureki O. Author Correction: Structural basis for the drug extrusion mechanism by a MATE multidrug transporter. Nature. PMID 32001809 DOI: 10.1038/S41586-019-1762-6 |
0.767 |
|
| 2019 |
Kondo T, Ando M, Nagai N, Tomisato W, Srirat T, Liu B, Mise-Omata S, Ikeda M, Chikuma S, Nishimasu H, Nureki O, Ohmura M, Hayakawa N, Hishiki T, Uchibori R, et al. The NOTCH-FOXM1 Axis Plays a Key Role in Mitochondrial Biogenesis in the Induction of Human Stem Cell Memory-like CAR-T Cells. Cancer Research. PMID 31767627 DOI: 10.1158/0008-5472.CAN-19-1196 |
0.564 |
|
| 2019 |
Jia Y, Zhao Y, Kusakizako T, Wang Y, Pan C, Zhang Y, Nureki O, Hattori M, Yan Z. TMC1 and TMC2 Proteins Are Pore-Forming Subunits of Mechanosensitive Ion Channels. Neuron. PMID 31761710 DOI: 10.1016/j.neuron.2019.10.017 |
0.65 |
|
| 2019 |
Nagano N, Honjo M, Kawaguchi M, Nishimasu H, Nureki O, Kano K, Aoki J, Komatsu T, Okabe T, Kojima H, Nagano T, Aihara M. Development of a Novel Intraocular-Pressure-Lowering Therapy Targeting ATX. Biological & Pharmaceutical Bulletin. 42: 1926-1935. PMID 31685776 DOI: 10.1248/Bpb.B19-00567 |
0.571 |
|
| 2019 |
Shihoya W, Inoue K, Singh M, Konno M, Hososhima S, Yamashita K, Ikeda K, Higuchi A, Izume T, Okazaki S, Hashimoto M, Mizutori R, Tomida S, Yamauchi Y, Abe-Yoshizumi R, ... ... Nureki O, et al. Crystal structure of heliorhodopsin. Nature. PMID 31554965 DOI: 10.1038/S41586-019-1604-6 |
0.394 |
|
| 2019 |
Hiraizumi M, Yamashita K, Nishizawa T, Nureki O. Cryo-EM structures capture the transport cycle of the P4-ATPase flippase. Science (New York, N.Y.). PMID 31416931 DOI: 10.1126/science.aay3353 |
0.637 |
|
| 2019 |
Lee Y, Wiriyasermkul P, Jin C, Quan L, Ohgaki R, Okuda S, Kusakizako T, Nishizawa T, Oda K, Ishitani R, Yokoyama T, Nakane T, Shirouzu M, Endou H, Nagamori S, ... ... Nureki O, et al. Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc. Nature Structural & Molecular Biology. PMID 31160781 DOI: 10.1038/s41594-019-0237-7 |
0.631 |
|
| 2019 |
Hirano S, Abudayyeh OO, Gootenberg JS, Horii T, Ishitani R, Hatada I, Zhang F, Nishimasu H, Nureki O. Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9. Nature Communications. 10: 1968. PMID 31036811 DOI: 10.1038/s41467-019-09741-6 |
0.643 |
|
| 2019 |
Umeda R, Nishizawa T, Nureki O. Crystallization of the human tetraspanin protein CD9. Acta Crystallographica. Section F, Structural Biology Communications. 75: 254-259. PMID 30950826 DOI: 10.1107/S2053230X1801840X |
0.625 |
|
| 2019 |
Kato T, Kumazaki K, Wada M, Taniguchi R, Nakane T, Yamashita K, Hirata K, Ishitani R, Ito K, Nishizawa T, Nureki O. Crystal structure of plant vacuolar iron transporter VIT1. Nature Plants. PMID 30742036 DOI: 10.1038/s41477-019-0367-2 |
0.637 |
|
| 2019 |
Endo M, Mikami M, Endo A, Kaya H, Itoh T, Nishimasu H, Nureki O, Toki S. Genome editing in plants by engineered CRISPR-Cas9 recognizing NG PAM. Nature Plants. 5: 14-17. PMID 30531939 DOI: 10.1038/s41477-018-0321-8 |
0.58 |
|
| 2018 |
Akichika S, Hirano S, Shichino Y, Suzuki T, Nishimasu H, Ishitani R, Sugita A, Hirose Y, Iwasaki S, Nureki O, Suzuki T. Cap-specific terminal -methylation of RNA by an RNA polymerase II-associated methyltransferase. Science (New York, N.Y.). PMID 30467178 DOI: 10.1126/Science.Aav0080 |
0.617 |
|
| 2018 |
Shihoya W, Izume T, Inoue A, Yamashita K, Kadji FMN, Hirata K, Aoki J, Nishizawa T, Nureki O. Crystal structures of human ET receptor provide mechanistic insight into receptor activation and partial activation. Nature Communications. 9: 4711. PMID 30413709 DOI: 10.1038/s41467-018-07094-0 |
0.62 |
|
| 2018 |
Kato K, Nishimasu H, Oikawa D, Hirano S, Hirano H, Kasuya G, Ishitani R, Tokunaga F, Nureki O. Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1. Nature Communications. 9: 4424. PMID 30356045 DOI: 10.1038/s41467-018-06922-7 |
0.66 |
|
| 2018 |
Yamamoto T, Endo Y, Onodera A, Hirahara K, Asou HK, Nakajima T, Kanno T, Ouchi Y, Uematsu S, Nishimasu H, Nureki O, Tumes DJ, Shimojo N, Nakayama T. DUSP10 constrains innate IL-33-mediated cytokine production in ST2 memory-type pathogenic Th2 cells. Nature Communications. 9: 4231. PMID 30315197 DOI: 10.1038/s41467-018-06468-8 |
0.552 |
|
| 2018 |
Oda K, Vierock J, Oishi S, Rodriguez-Rozada S, Taniguchi R, Yamashita K, Wiegert JS, Nishizawa T, Hegemann P, Nureki O. Crystal structure of the red light-activated channelrhodopsin Chrimson. Nature Communications. 9: 3949. PMID 30258177 DOI: 10.1038/s41467-018-06421-9 |
0.664 |
|
| 2018 |
Cheng C, Kamiya M, Takemoto M, Ishitani R, Nureki O, Yoshida N, Hayashi S. An Atomistic Model of a Precursor State of Light-Induced Channel Opening of Channelrhodopsin. Biophysical Journal. PMID 30236783 DOI: 10.1016/j.bpj.2018.08.024 |
0.359 |
|
| 2018 |
Nishimasu H, Shi X, Ishiguro S, Gao L, Hirano S, Okazaki S, Noda T, Abudayyeh OO, Gootenberg JS, Mori H, Oura S, Holmes B, Tanaka M, Seki M, Hirano H, ... ... Nureki O, et al. Engineered CRISPR-Cas9 nuclease with expanded targeting space. Science (New York, N.Y.). PMID 30166441 DOI: 10.1126/Science.Aas9129 |
0.618 |
|
| 2018 |
Kasuya G, Nakane T, Yokoyama T, Jia Y, Inoue M, Watanabe K, Nakamura R, Nishizawa T, Kusakizako T, Tsutsumi A, Yanagisawa H, Dohmae N, Hattori M, Ichijo H, Yan Z, ... ... Nureki O, et al. Cryo-EM structures of the human volume-regulated anion channel LRRC8. Nature Structural & Molecular Biology. PMID 30127360 DOI: 10.1038/s41594-018-0109-6 |
0.787 |
|
| 2018 |
Osuka S, Isomura K, Kajimoto S, Komori T, Nishimasu H, Shima T, Nureki O, Uemura S. Real-time observation of flexible domain movements in CRISPR-Cas9. The Embo Journal. 37. PMID 29650679 DOI: 10.15252/embj.201796941 |
0.631 |
|
| 2018 |
Ouchi Y, Patil A, Tamura Y, Nishimasu H, Negishi A, Paul SK, Takemura N, Satoh T, Kimura Y, Kurachi M, Nureki O, Nakai K, Kiyono H, Uematsu S. Generation of tumor antigen-specific murine CD8+ T cells with enhanced anti-tumor activity via highly efficient CRISPR/Cas9 genome editing. International Immunology. 30: 141-154. PMID 29617862 DOI: 10.1093/intimm/dxy006 |
0.579 |
|
| 2018 |
Maruyama T, Imai S, Kusakizako T, Hattori M, Ishitani R, Nureki O, Ito K, Maturana AD, Shimada I, Osawa M. Functional roles of Mg binding sites in ion-dependent gating of a Mg channel, MgtE, revealed by solution NMR. Elife. 7. PMID 29611805 DOI: 10.7554/eLife.31596 |
0.643 |
|
| 2017 |
Miyauchi H, Moriyama S, Kusakizako T, Kumazaki K, Nakane T, Yamashita K, Hirata K, Dohmae N, Nishizawa T, Ito K, Miyaji T, Moriyama Y, Ishitani R, Nureki O. Structural basis for xenobiotic extrusion by eukaryotic MATE transporter. Nature Communications. 8: 1633. PMID 29158478 DOI: 10.1038/s41467-017-01541-0 |
0.651 |
|
| 2017 |
Shibata M, Nishimasu H, Kodera N, Hirano S, Ando T, Uchihashi T, Nureki O. Real-space and real-time dynamics of CRISPR-Cas9 visualized by high-speed atomic force microscopy. Nature Communications. 8: 1430. PMID 29127285 DOI: 10.1038/s41467-017-01466-8 |
0.617 |
|
| 2017 |
Kasuya G, Yamaura T, Ma XB, Nakamura R, Takemoto M, Nagumo H, Tanaka E, Dohmae N, Nakane T, Yu Y, Ishitani R, Matsuzaki O, Hattori M, Nureki O. Structural insights into the competitive inhibition of the ATP-gated P2X receptor channel. Nature Communications. 8: 876. PMID 29026074 DOI: 10.1038/s41467-017-00887-9 |
0.685 |
|
| 2017 |
Lee Y, Nishizawa T, Takemoto M, Kumazaki K, Yamashita K, Hirata K, Minoda A, Nagatoishi S, Tsumoto K, Ishitani R, Nureki O. Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity. Nature Plants. PMID 28970497 DOI: 10.1038/s41477-017-0022-8 |
0.679 |
|
| 2017 |
Shihoya W, Nishizawa T, Yamashita K, Inoue A, Hirata K, Kadji FMN, Okuta A, Tani K, Aoki J, Fujiyoshi Y, Doi T, Nureki O. X-ray structures of endothelin ETB receptor bound to clinical antagonist bosentan and its analog. Nature Structural & Molecular Biology. PMID 28805809 DOI: 10.1038/Nsmb.3450 |
0.651 |
|
| 2017 |
Taniguchi R, Inoue A, Sayama M, Uwamizu A, Yamashita K, Hirata K, Yoshida M, Tanaka Y, Kato HE, Nakada-Nakura Y, Otani Y, Nishizawa T, Doi T, Ohwada T, Ishitani R, ... ... Nureki O, et al. Structural insights into ligand recognition by the lysophosphatidic acid receptor LPA6. Nature. PMID 28792932 DOI: 10.1038/Nature23448 |
0.774 |
|
| 2017 |
Yamano T, Zetsche B, Ishitani R, Zhang F, Nishimasu H, Nureki O. Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1. Molecular Cell. PMID 28781234 DOI: 10.1016/J.Molcel.2017.06.035 |
0.653 |
|
| 2017 |
Tomita A, Zhang M, Jin F, Zhuang W, Takeda H, Maruyama T, Osawa M, Hashimoto KI, Kawasaki H, Ito K, Dohmae N, Ishitani R, Shimada I, Yan Z, Hattori M, ... Nureki O, et al. ATP-dependent modulation of MgtE in Mg(2+) homeostasis. Nature Communications. 8: 148. PMID 28747715 DOI: 10.1038/s41467-017-00082-w |
0.673 |
|
| 2017 |
Nishimasu H, Yamano T, Gao L, Zhang F, Ishitani R, Nureki O. Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1. Molecular Cell. PMID 28595896 DOI: 10.1016/J.Molcel.2017.04.019 |
0.656 |
|
| 2017 |
Gao L, Cox DBT, Yan WX, Manteiga JC, Schneider MW, Yamano T, Nishimasu H, Nureki O, Crosetto N, Zhang F. Engineered Cpf1 variants with altered PAM specificities. Nature Biotechnology. PMID 28581492 DOI: 10.1038/Nbt.3900 |
0.617 |
|
| 2017 |
Kasuya G, Fujiwara Y, Tsukamoto H, Morinaga S, Ryu S, Touhara K, Ishitani R, Furutani Y, Hattori M, Nureki O. Structural insights into the nucleotide base specificity of P2X receptors. Scientific Reports. 7: 45208. PMID 28332633 DOI: 10.1038/srep45208 |
0.7 |
|
| 2017 |
Yamada M, Watanabe Y, Gootenberg JS, Hirano H, Ran FA, Nakane T, Ishitani R, Zhang F, Nishimasu H, Nureki O. Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems. Molecular Cell. 65: 1109-1121.e3. PMID 28306506 DOI: 10.1016/J.Molcel.2017.02.007 |
0.646 |
|
| 2016 |
Nango E, Royant A, Kubo M, Nakane T, Wickstrand C, Kimura T, Tanaka T, Tono K, Song C, Tanaka R, Arima T, Yamashita A, Kobayashi J, Hosaka T, Mizohata E, ... ... Nureki O, et al. A three-dimensional movie of structural changes in bacteriorhodopsin. Science (New York, N.Y.). 354: 1552-1557. PMID 28008064 DOI: 10.1126/Science.Aah3497 |
0.638 |
|
| 2016 |
Nishimasu H, Nureki O. Structures and mechanisms of CRISPR RNA-guided effector nucleases. Current Opinion in Structural Biology. 43: 68-78. PMID 27912110 DOI: 10.1016/j.sbi.2016.11.013 |
0.614 |
|
| 2016 |
Kasuya G, Hiraizumi M, Maturana AD, Kumazaki K, Fujiwara Y, Liu K, Nakada-Nakura Y, Iwata S, Tsukada K, Komori T, Uemura S, Goto Y, Nakane T, Takemoto M, Kato HE, ... ... Nureki O, et al. Crystal structures of the TRIC trimeric intracellular cation channel orthologues. Cell Research. 26: 1288-1301. PMID 27909292 DOI: 10.1038/Cr.2016.140 |
0.789 |
|
| 2016 |
Kato HE, Inoue K, Kandori H, Nureki O. The light-driven sodium ion pump: A new player in rhodopsin research. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 27859420 DOI: 10.1002/Bies.201600065 |
0.652 |
|
| 2016 |
Matsumoto N, Nishimasu H, Sakakibara K, Nishida KM, Hirano T, Ishitani R, Siomi H, Siomi MC, Nureki O. Crystal Structure of Silkworm PIWI-Clade Argonaute Siwi Bound to piRNA. Cell. 167: 484-497.e9. PMID 27693359 DOI: 10.1016/j.cell.2016.09.002 |
0.68 |
|
| 2016 |
Abe-Yoshizumi R, Inoue K, Kato HE, Nureki O, Kandori H. Role of Asn112 in a light-driven sodium ion-pumping rhodopsin. Biochemistry. PMID 27673340 DOI: 10.1021/Acs.Biochem.6B00741 |
0.633 |
|
| 2016 |
Shihoya W, Nishizawa T, Okuta A, Tani K, Dohmae N, Fujiyoshi Y, Nureki O, Doi T. Activation mechanism of endothelin ETB receptor by endothelin-1. Nature. PMID 27595334 DOI: 10.1038/Nature19319 |
0.631 |
|
| 2016 |
Morita J, Kato K, Nakane T, Kondo Y, Fukuda H, Nishimasu H, Ishitani R, Nureki O. Crystal structure of the plant receptor-like kinase TDR in complex with the TDIF peptide. Nature Communications. 7: 12383. PMID 27498761 DOI: 10.1038/ncomms12383 |
0.63 |
|
| 2016 |
Kato K, Satouh Y, Nishimasu H, Kurabayashi A, Morita J, Fujihara Y, Oji A, Ishitani R, Ikawa M, Nureki O. Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization. Nature Communications. 7: 12198. PMID 27416963 DOI: 10.1038/ncomms12198 |
0.652 |
|
| 2016 |
Tsuchiya H, Doki S, Takemoto M, Ikuta T, Higuchi T, Fukui K, Usuda Y, Tabuchi E, Nagatoishi S, Tsumoto K, Nishizawa T, Ito K, Dohmae N, Ishitani R, Nureki O. Structural basis for amino acid export by DMT superfamily transporter YddG. Nature. PMID 27281193 DOI: 10.1038/nature17991 |
0.696 |
|
| 2016 |
Yamano T, Nishimasu H, Zetsche B, Hirano H, Slaymaker IM, Li Y, Fedorova I, Nakane T, Makarova KS, Koonin EV, Ishitani R, Zhang F, Nureki O. Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA. Cell. PMID 27114038 DOI: 10.1016/j.cell.2016.04.003 |
0.648 |
|
| 2016 |
Minato Y, Suzuki S, Hara T, Kofuku Y, Kasuya G, Fujiwara Y, Igarashi S, Suzuki EI, Nureki O, Hattori M, Ueda T, Shimada I. Conductance of P2X4 purinergic receptor is determined by conformational equilibrium in the transmembrane region. Proceedings of the National Academy of Sciences of the United States of America. PMID 27071117 DOI: 10.1073/pnas.1600519113 |
0.665 |
|
| 2016 |
Kato K, Ikeda H, Miyakawa S, Futakawa S, Nonaka Y, Fujiwara M, Okudaira S, Kano K, Aoki J, Morita J, Ishitani R, Nishimasu H, Nakamura Y, Nureki O. Structural basis for specific inhibition of Autotaxin by a DNA aptamer. Nature Structural & Molecular Biology. PMID 27043297 DOI: 10.1038/nsmb.3200 |
0.61 |
|
| 2016 |
Hirano S, Nishimasu H, Ishitani R, Nureki O. Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9. Molecular Cell. 61: 886-94. PMID 26990991 DOI: 10.1016/j.molcel.2016.02.018 |
0.649 |
|
| 2016 |
Morita J, Kano K, Kato K, Takita H, Sakagami H, Yamamoto Y, Mihara E, Ueda H, Sato T, Tokuyama H, Arai H, Asou H, Takagi J, Ishitani R, Nishimasu H, ... Nureki O, et al. Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase. Scientific Reports. 6: 20995. PMID 26888014 DOI: 10.1038/Srep20995 |
0.62 |
|
| 2016 |
Hirano H, Gootenberg JS, Horii T, Abudayyeh OO, Kimura M, Hsu PD, Nakane T, Ishitani R, Hatada I, Zhang F, Nishimasu H, Nureki O. Structure and Engineering of Francisella novicida Cas9. Cell. PMID 26875867 DOI: 10.1016/J.Cell.2016.01.039 |
0.647 |
|
| 2016 |
Kasuya G, Fujiwara Y, Takemoto M, Dohmae N, Nakada-Nakura Y, Ishitani R, Hattori M, Nureki O. Structural Insights into Divalent Cation Modulations of ATP-Gated P2X Receptor Channels. Cell Reports. 14: 932-944. PMID 26804916 DOI: 10.1016/j.celrep.2015.12.087 |
0.687 |
|
| 2016 |
Konno M, Kato Y, Kato HE, Inoue K, Nureki O, Kandori H. Mutant of a Light-Driven Sodium Ion Pump Can Transport Cesium Ions. The Journal of Physical Chemistry Letters. 7: 51-5. PMID 26740141 DOI: 10.1021/Acs.Jpclett.5B02385 |
0.638 |
|
| 2015 |
Tanaka Y, Sugano Y, Takemoto M, Mori T, Furukawa A, Kusakizako T, Kumazaki K, Kashima A, Ishitani R, Sugita Y, Nureki O, Tsukazaki T. Crystal Structures of SecYEG in Lipidic Cubic Phase Elucidate a Precise Resting and a Peptide-Bound State. Cell Reports. PMID 26586438 DOI: 10.1016/j.celrep.2015.10.025 |
0.395 |
|
| 2015 |
Taniguchi R, Kato HE, Font J, Deshpande CN, Wada M, Ito K, Ishitani R, Jormakka M, Nureki O. Outward- and inward-facing structures of a putative bacterial transition-metal transporter with homology to ferroportin. Nature Communications. 6: 8545. PMID 26461048 DOI: 10.1038/Ncomms9545 |
0.678 |
|
| 2015 |
Nishimasu H, Cong L, Yan WX, Ran FA, Zetsche B, Li Y, Kurabayashi A, Ishitani R, Zhang F, Nureki O. Crystal Structure of Staphylococcus aureus Cas9. Cell. 162: 1113-26. PMID 26317473 DOI: 10.1016/J.Cell.2015.08.007 |
0.664 |
|
| 2015 |
Takemoto M, Kato HE, Koyama M, Ito J, Kamiya M, Hayashi S, Maturana AD, Deisseroth K, Ishitani R, Nureki O. Molecular Dynamics of Channelrhodopsin at the Early Stages of Channel Opening. Plos One. 10: e0131094. PMID 26114863 DOI: 10.1371/Journal.Pone.0131094 |
0.67 |
|
| 2015 |
Kato HE, Kamiya M, Sugo S, Ito J, Taniguchi R, Orito A, Hirata K, Inutsuka A, Yamanaka A, Maturana AD, Ishitani R, Sudo Y, Hayashi S, Nureki O. Atomistic design of microbial opsin-based blue-shifted optogenetics tools. Nature Communications. 6: 7177. PMID 25975962 DOI: 10.1038/Ncomms8177 |
0.661 |
|
| 2015 |
Fukuda M, Takeda H, Kato HE, Doki S, Ito K, Maturana AD, Ishitani R, Nureki O. Structural basis for dynamic mechanism of nitrate/nitrite antiport by NarK. Nature Communications. 6: 7097. PMID 25959928 DOI: 10.1038/Ncomms8097 |
0.703 |
|
| 2015 |
Matsumoto N, Sato K, Nishimasu H, Namba Y, Miyakubi K, Dohmae N, Ishitani R, Siomi H, Siomi MC, Nureki O. Crystal Structure and Activity of the Endoribonuclease Domain of the piRNA Pathway Factor Maelstrom. Cell Reports. 11: 366-75. PMID 25865890 DOI: 10.1016/j.celrep.2015.03.030 |
0.667 |
|
| 2015 |
Kato HE, Inoue K, Abe-Yoshizumi R, Kato Y, Ono H, Konno M, Hososhima S, Ishizuka T, Hoque MR, Kunitomo H, Ito J, Yoshizawa S, Yamashita K, Takemoto M, Nishizawa T, ... ... Nureki O, et al. Structural basis for Na(+) transport mechanism by a light-driven Na(+) pump. Nature. 521: 48-53. PMID 25849775 DOI: 10.1038/Nature14322 |
0.774 |
|
| 2015 |
Inaguma A, Tsukamoto H, Kato HE, Kimura T, Ishizuka T, Oishi S, Yawo H, Nureki O, Furutani Y. Chimeras of channelrhodopsin-1 and -2 from Chlamydomonas reinhardtii exhibit distinctive light-induced structural changes from channelrhodopsin-2. The Journal of Biological Chemistry. 290: 11623-34. PMID 25796616 DOI: 10.1074/Jbc.M115.642256 |
0.676 |
|
| 2015 |
Lee Y, Nishizawa T, Yamashita K, Ishitani R, Nureki O. Structural basis for the facilitative diffusion mechanism by SemiSWEET transporter. Nature Communications. 6: 6112. PMID 25598322 DOI: 10.1038/ncomms7112 |
0.673 |
|
| 2015 |
Konermann S, Brigham MD, Trevino AE, Joung J, Abudayyeh OO, Barcena C, Hsu PD, Habib N, Gootenberg JS, Nishimasu H, Nureki O, Zhang F. Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex. Nature. 517: 583-8. PMID 25494202 DOI: 10.1038/Nature14136 |
0.598 |
|
| 2014 |
Takeda H, Hattori M, Nishizawa T, Yamashita K, Shah ST, Caffrey M, Maturana AD, Ishitani R, Nureki O. Structural basis for ion selectivity revealed by high-resolution crystal structure of Mg2+ channel MgtE. Nature Communications. 5: 5374. PMID 25367295 DOI: 10.1038/Ncomms6374 |
0.783 |
|
| 2014 |
Pescitelli G, Kato HE, Oishi S, Ito J, Maturana AD, Nureki O, Woody RW. Exciton circular dichroism in channelrhodopsin. The Journal of Physical Chemistry. B. 118: 11873-85. PMID 25247388 DOI: 10.1021/Jp505917P |
0.643 |
|
| 2014 |
Kumazaki K, Tsukazaki T, Nishizawa T, Tanaka Y, Kato HE, Nakada-Nakura Y, Hirata K, Mori Y, Suga H, Dohmae N, Ishitani R, Nureki O. Crystallization and preliminary X-ray diffraction analysis of YidC, a membrane-protein chaperone and insertase from Bacillus halodurans. Acta Crystallographica. Section F, Structural Biology Communications. 70: 1056-60. PMID 25084381 DOI: 10.1107/S2053230X14012540 |
0.765 |
|
| 2014 |
Morita J, Kato K, Mihara E, Ishitani R, Takagi J, Nishimasu H, Aoki J, Nureki O. Expression, purification, crystallization and preliminary X-ray crystallographic analysis of Enpp6. Acta Crystallographica. Section F, Structural Biology Communications. 70: 794-9. PMID 24915096 DOI: 10.1107/S2053230X14008929 |
0.607 |
|
| 2014 |
Suzuki H, Nishizawa T, Tani K, Yamazaki Y, Tamura A, Ishitani R, Dohmae N, Tsukita S, Nureki O, Fujiyoshi Y. Crystal structure of a claudin provides insight into the architecture of tight junctions. Science (New York, N.Y.). 344: 304-7. PMID 24744376 DOI: 10.1126/Science.1248571 |
0.658 |
|
| 2014 |
Nishimasu H, Ran FA, Hsu PD, Konermann S, Shehata SI, Dohmae N, Ishitani R, Zhang F, Nureki O. Crystal structure of Cas9 in complex with guide RNA and target DNA. Cell. 156: 935-49. PMID 24529477 DOI: 10.1016/J.Cell.2014.02.001 |
0.645 |
|
| 2014 |
Ito S, Kato HE, Taniguchi R, Iwata T, Nureki O, Kandori H. Water-containing hydrogen-bonding network in the active center of channelrhodopsin. Journal of the American Chemical Society. 136: 3475-82. PMID 24512107 DOI: 10.1021/Ja410836G |
0.643 |
|
| 2014 |
Yamagata K, Goto Y, Nishimasu H, Morimoto J, Ishitani R, Dohmae N, Takeda N, Nagai R, Komuro I, Suga H, Nureki O. Structural basis for potent inhibition of SIRT2 deacetylase by a macrocyclic peptide inducing dynamic structural change. Structure (London, England : 1993). 22: 345-52. PMID 24389023 DOI: 10.1016/J.Str.2013.12.001 |
0.648 |
|
| 2014 |
Mio K, Tsukazaki T, Mori H, Kawata M, Moriya T, Sasaki Y, Ishitani R, Ito K, Nureki O, Sato C. Conformational variation of the translocon enhancing chaperone SecDF. Journal of Structural and Functional Genomics. 15: 107-15. PMID 24368747 DOI: 10.1007/s10969-013-9168-4 |
0.304 |
|
| 2013 |
Kato HE, Nureki O. Crystal structure of channelrhodopsin, a light-gated cation channel - all cations lead through the monomer. Biophysics (Nagoya-Shi, Japan). 9: 57-61. PMID 27493541 DOI: 10.2142/Biophysics.9.57 |
0.675 |
|
| 2013 |
Nishimasu H, Ishitani R, Nureki O. [Structural biology of ubiquitin signaling]. Seikagaku. the Journal of Japanese Biochemical Society. 85: 423-9. PMID 23875469 |
0.608 |
|
| 2013 |
Doki S, Kato HE, Solcan N, Iwaki M, Koyama M, Hattori M, Iwase N, Tsukazaki T, Sugita Y, Kandori H, Newstead S, Ishitani R, Nureki O. Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT. Proceedings of the National Academy of Sciences of the United States of America. 110: 11343-8. PMID 23798427 DOI: 10.2142/Biophys.54.085 |
0.779 |
|
| 2013 |
Nishizawa T, Kita S, Maturana AD, Furuya N, Hirata K, Kasuya G, Ogasawara S, Dohmae N, Iwamoto T, Ishitani R, Nureki O. Structural basis for the counter-transport mechanism of a H+/Ca2+ exchanger. Science (New York, N.Y.). 341: 168-72. PMID 23704374 DOI: 10.1126/science.1239002 |
0.631 |
|
| 2013 |
Kawaguchi M, Okabe T, Okudaira S, Nishimasu H, Ishitani R, Kojima H, Nureki O, Aoki J, Nagano T. Screening and X-ray crystal structure-based optimization of autotaxin (ENPP2) inhibitors, using a newly developed fluorescence probe. Acs Chemical Biology. 8: 1713-21. PMID 23688339 DOI: 10.1021/Cb400150C |
0.606 |
|
| 2013 |
Tanaka Y, Hipolito CJ, Maturana AD, Ito K, Kuroda T, Higuchi T, Katoh T, Kato HE, Hattori M, Kumazaki K, Tsukazaki T, Ishitani R, Suga H, Nureki O. Structural basis for the drug extrusion mechanism by a MATE multidrug transporter. Nature. 496: 247-51. PMID 23535598 DOI: 10.1038/Nature12014 |
0.784 |
|
| 2013 |
Nozawa K, Ishitani R, Yoshihisa T, Sato M, Arisaka F, Kanamaru S, Dohmae N, Mangroo D, Senger B, Becker HD, Nureki O. Crystal structure of Cex1p reveals the mechanism of tRNA trafficking between nucleus and cytoplasm. Nucleic Acids Research. 41: 3901-14. PMID 23396276 DOI: 10.1093/nar/gkt010 |
0.803 |
|
| 2013 |
Maruyama T, Imai S, Osawa M, Hattori M, Ishitani R, Nureki O, Shimada I. Backbone resonance assignments for the cytoplasmic region of the Mg(2+) transporter MgtE in the Mg (2+)-unbound state. Biomolecular Nmr Assignments. 7: 93-6. PMID 22477092 DOI: 10.1007/s12104-012-9385-y |
0.623 |
|
| 2012 |
Fukuhara S, Nishimasu H, Bonnefond L, Matsumoto N, Ishitani R, Nureki O. Expression, purification, crystallization and preliminary X-ray crystallographic analysis of Zucchini from Drosophila melanogaster. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 68: 1346-50. PMID 23143246 DOI: 10.1107/S1744309112038936 |
0.621 |
|
| 2012 |
Yamagami R, Yamashita K, Nishimasu H, Tomikawa C, Ochi A, Iwashita C, Hirata A, Ishitani R, Nureki O, Hori H. The tRNA recognition mechanism of folate/FAD-dependent tRNA methyltransferase (TrmFO). The Journal of Biological Chemistry. 287: 42480-94. PMID 23095745 DOI: 10.1074/jbc.M112.390112 |
0.609 |
|
| 2012 |
Nishimasu H, Ishizu H, Saito K, Fukuhara S, Kamatani MK, Bonnefond L, Matsumoto N, Nishizawa T, Nakanaga K, Aoki J, Ishitani R, Siomi H, Siomi MC, Nureki O. Structure and function of Zucchini endoribonuclease in piRNA biogenesis. Nature. 491: 284-7. PMID 23064230 DOI: 10.1038/nature11509 |
0.765 |
|
| 2012 |
Tokunaga F, Nishimasu H, Ishitani R, Goto E, Noguchi T, Mio K, Kamei K, Ma A, Iwai K, Nureki O. Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation. The Embo Journal. 31: 3856-70. PMID 23032187 DOI: 10.1038/Emboj.2012.241 |
0.596 |
|
| 2012 |
Kato K, Nishimasu H, Okudaira S, Mihara E, Ishitani R, Takagi J, Aoki J, Nureki O. Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling. Proceedings of the National Academy of Sciences of the United States of America. 109: 16876-81. PMID 23027977 DOI: 10.1073/pnas.1208017109 |
0.655 |
|
| 2012 |
Koyama M, Nishimasu H, Ishitani R, Nureki O. Molecular dynamics simulation of Autotaxin: roles of the nuclease-like domain and the glycan modification. The Journal of Physical Chemistry. B. 116: 11798-808. PMID 22967301 DOI: 10.1021/jp303198u |
0.586 |
|
| 2012 |
Kawahara-Kobayashi A, Masuda A, Araiso Y, Sakai Y, Kohda A, Uchiyama M, Asami S, Matsuda T, Ishitani R, Dohmae N, Yokoyama S, Kigawa T, Nureki O, Kiga D. Simplification of the genetic code: restricted diversity of genetically encoded amino acids. Nucleic Acids Research. 40: 10576-84. PMID 22909996 DOI: 10.1093/nar/gks786 |
0.305 |
|
| 2012 |
Kato K, Nishimasu H, Mihara E, Ishitani R, Takagi J, Aoki J, Nureki O. Expression, purification, crystallization and preliminary X-ray crystallographic analysis of Enpp1. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 68: 778-82. PMID 22750863 DOI: 10.1107/S1744309112019306 |
0.602 |
|
| 2012 |
Imai S, Maruyama T, Osawa M, Hattori M, Ishitani R, Nureki O, Shimada I. Spatial distribution of cytoplasmic domains of the Mg(2+)-transporter MgtE, in a solution lacking Mg(2+), revealed by paramagnetic relaxation enhancement. Biochimica Et Biophysica Acta. 1824: 1129-35. PMID 22743077 DOI: 10.1016/j.bbapap.2012.06.008 |
0.666 |
|
| 2012 |
Nishimasu H, Ishitani R, Aoki J, Nureki O. A 3D view of autotaxin. Trends in Pharmacological Sciences. 33: 138-45. PMID 22277299 DOI: 10.1016/j.tips.2011.12.004 |
0.611 |
|
| 2012 |
Kato HE, Zhang F, Yizhar O, Ramakrishnan C, Nishizawa T, Hirata K, Ito J, Aita Y, Tsukazaki T, Hayashi S, Hegemann P, Maturana AD, Ishitani R, Deisseroth K, Nureki O. Crystal structure of the channelrhodopsin light-gated cation channel. Nature. 482: 369-74. PMID 22266941 DOI: 10.1038/Nature10870 |
0.79 |
|
| 2012 |
Katayama H, Nozawa K, Nureki O, Nakahara Y, Hojo H. Pyrrolysine analogs as substrates for bacterial pyrrolysyl-tRNA synthetase in vitro and in vivo. Bioscience, Biotechnology, and Biochemistry. 76: 205-8. PMID 22232266 DOI: 10.1271/bbb.110653 |
0.766 |
|
| 2011 |
Nishimasu H, Okudaira S, Hama K, Mihara E, Dohmae N, Inoue A, Ishitani R, Takagi J, Aoki J, Nureki O. Crystal structure of autotaxin and insight into GPCR activation by lipid mediators. Nature Structural & Molecular Biology. 18: 205-12. PMID 21240269 DOI: 10.1038/nsmb.1998 |
0.675 |
|
| 2011 |
Kato M, Araiso Y, Noma A, Nagao A, Suzuki T, Ishitani R, Nureki O. Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification. Nucleic Acids Research. 39: 1576-85. PMID 20972222 DOI: 10.1093/nar/gkq919 |
0.306 |
|
| 2010 |
Nozawa K, Ishitani R, Nureki O. [Pyrrolysyl-tRNA synthetase-tRNA(Pyl) structure reveals the molecular basis of orthogonality]. Seikagaku. the Journal of Japanese Biochemical Society. 82: 617-23. PMID 20715574 |
0.79 |
|
| 2009 |
Nakanishi K, Bonnefond L, Kimura S, Suzuki T, Ishitani R, Nureki O. Structural basis for translational fidelity ensured by transfer RNA lysidine synthetase. Nature. 461: 1144-8. PMID 19847269 DOI: 10.1038/nature08474 |
0.72 |
|
| 2009 |
Hattori M, Iwase N, Furuya N, Tanaka Y, Tsukazaki T, Ishitani R, Maguire ME, Ito K, Maturana A, Nureki O. Mg(2+)-dependent gating of bacterial MgtE channel underlies Mg(2+) homeostasis. The Embo Journal. 28: 3602-12. PMID 19798051 DOI: 10.1038/emboj.2009.288 |
0.63 |
|
| 2009 |
Hattori M, Jin Y, Nishimasu H, Tanaka Y, Mochizuki M, Uchiumi T, Ishitani R, Ito K, Nureki O. Structural basis of novel interactions between the small-GTPase and GDI-like domains in prokaryotic FeoB iron transporter. Structure (London, England : 1993). 17: 1345-55. PMID 19733088 DOI: 10.1016/j.str.2009.08.007 |
0.769 |
|
| 2009 |
Umitsu M, Nishimasu H, Noma A, Suzuki T, Ishitani R, Nureki O. Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2. Proceedings of the National Academy of Sciences of the United States of America. 106: 15616-21. PMID 19717466 DOI: 10.1073/pnas.0905270106 |
0.628 |
|
| 2009 |
Jin Y, Hattori M, Nisimasu H, Ishitani R, Nureki O. Crystallization and preliminary X-ray diffraction analysis of the truncated cytosolic domain of the iron transporter FeoB. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 784-7. PMID 19652339 DOI: 10.1107/S1744309109024464 |
0.674 |
|
| 2009 |
Higuchi T, Hattori M, Tanaka Y, Ishitani R, Nureki O. Crystal structure of the cytosolic domain of the cation diffusion facilitator family protein. Proteins. 76: 768-71. PMID 19422055 DOI: 10.1002/prot.22444 |
0.674 |
|
| 2009 |
Nishimasu H, Ishitani R, Yamashita K, Iwashita C, Hirata A, Hori H, Nureki O. Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase. Proceedings of the National Academy of Sciences of the United States of America. 106: 8180-5. PMID 19416846 DOI: 10.1073/pnas.0901330106 |
0.657 |
|
| 2009 |
Nozawa K, O'Donoghue P, Gundllapalli S, Araiso Y, Ishitani R, Umehara T, Söll D, Nureki O. Pyrrolysyl-tRNA synthetase-tRNA(Pyl) structure reveals the molecular basis of orthogonality. Nature. 457: 1163-7. PMID 19118381 DOI: 10.1038/Nature07611 |
0.784 |
|
| 2009 |
Nureki O, Hattori M, Ishitani R. [Mechanism of cellular magnesium balance regulation by a magnesium transporter]. Seikagaku. the Journal of Japanese Biochemical Society. 80: 933-9. PMID 19039979 |
0.633 |
|
| 2008 |
Ishitani R, Sugita Y, Dohmae N, Furuya N, Hattori M, Nureki O. Mg2+-sensing mechanism of Mg2+ transporter MgtE probed by molecular dynamics study. Proceedings of the National Academy of Sciences of the United States of America. 105: 15393-8. PMID 18832160 DOI: 10.1073/pnas.0802991105 |
0.631 |
|
| 2008 |
Ishitani R, Yokoyama S, Nureki O. Structure, dynamics, and function of RNA modification enzymes. Current Opinion in Structural Biology. 18: 330-9. PMID 18539024 DOI: 10.1016/j.sbi.2008.05.003 |
0.431 |
|
| 2008 |
Hattori M, Nureki O. [Structural basis for the mechanism of Mg2 homeostasis by MgtE transporter]. Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. 53: 242-8. PMID 18326297 |
0.671 |
|
| 2007 |
Hattori M, Tanaka Y, Ishitani R, Nureki O. Crystallization and preliminary X-ray diffraction analysis of the cytosolic domain of a cation diffusion facilitator family protein. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63: 771-3. PMID 17768351 DOI: 10.1107/S1744309107038948 |
0.665 |
|
| 2007 |
Hattori M, Tanaka Y, Fukai S, Ishitani R, Nureki O. Crystal structure of the MgtE Mg2+ transporter. Nature. 448: 1072-5. PMID 17700703 DOI: 10.1038/nature06093 |
0.688 |
|
| 2007 |
Hattori M, Tanaka Y, Fukai S, Ishitani R, Nureki O. Crystallization and preliminary X-ray diffraction analysis of the full-length Mg2+ transporter MgtE. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63: 682-4. PMID 17671367 DOI: 10.1107/S1744309107032332 |
0.665 |
|
| 2007 |
Tanaka Y, Hattori M, Fukai S, Ishitania R, Nureki O. Crystallization and preliminary X-ray diffraction analysis of the cytosolic domain of the Mg2+ transporter MgtE. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63: 678-81. PMID 17671366 DOI: 10.1107/S1744309107032344 |
0.669 |
|
| 2007 |
Sato Y, Shirakawa R, Horiuchi H, Dohmae N, Fukai S, Nureki O. Asymmetric coiled-coil structure with Guanine nucleotide exchange activity. Structure (London, England : 1993). 15: 245-52. PMID 17292842 DOI: 10.1016/j.str.2007.01.003 |
0.313 |
|
| 2006 |
Yanagisawa T, Ishii R, Fukunaga R, Nureki O, Yokoyama S. Crystallization and preliminary X-ray crystallographic analysis of the catalytic domain of pyrrolysyl-tRNA synthetase from the methanogenic archaeon Methanosarcina mazei. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 1031-3. PMID 17012805 DOI: 10.1107/S1744309106036700 |
0.415 |
|
| 2006 |
Sengoku T, Nureki O, Nakamura A, Kobayashi S, Yokoyama S. Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa. Cell. 125: 287-300. PMID 16630817 DOI: 10.1016/j.cell.2006.01.054 |
0.453 |
|
| 2005 |
Fukunaga R, Ishitani R, Nureki O, Yokoyama S. Crystallization of leucyl-tRNA synthetase complexed with tRNALeu from the archaeon Pyrococcus horikoshii. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 30-2. PMID 16508082 DOI: 10.1107/S1744309104021827 |
0.389 |
|
| 2005 |
Nakanishi K, Ogiso Y, Nakama T, Fukai S, Nureki O. Structural basis for anticodon recognition by methionyl-tRNA synthetase. Nature Structural & Molecular Biology. 12: 931-2. PMID 16155581 DOI: 10.1038/nsmb988 |
0.72 |
|
| 2005 |
Nakanishi K, Fukai S, Ikeuchi Y, Soma A, Sekine Y, Suzuki T, Nureki O. Structural basis for lysidine formation by ATP pyrophosphatase accompanied by a lysine-specific loop and a tRNA-recognition domain. Proceedings of the National Academy of Sciences of the United States of America. 102: 7487-92. PMID 15894617 DOI: 10.1073/Pnas.0501003102 |
0.715 |
|
| 2005 |
Nakanishi K, Nureki O. Recent progress of structural biology of tRNA processing and modification. Molecules and Cells. 19: 157-66. PMID 15879697 |
0.723 |
|
| 2005 |
Watanabe K, Nureki O, Fukai S, Ishii R, Okamoto H, Yokoyama S, Endo Y, Hori H. Roles of conserved amino acid sequence motifs in the SpoU (TrmH) RNA methyltransferase family. The Journal of Biological Chemistry. 280: 10368-77. PMID 15637073 DOI: 10.1074/jbc.M411209200 |
0.441 |
|
| 2004 |
Katsura Y, Shirouzu M, Yamaguchi H, Ishitani R, Nureki O, Kuramitsu S, Hayashi H, Yokoyama S. Crystal structure of a putative aspartate aminotransferase belonging to subgroup IV. Proteins. 55: 487-92. PMID 15103612 DOI: 10.1002/prot.20020 |
0.432 |
|
| 2004 |
Nureki O, Watanabe K, Fukai S, Ishii R, Endo Y, Hori H, Yokoyama S. Deep knot structure for construction of active site and cofactor binding site of tRNA modification enzyme. Structure (London, England : 1993). 12: 593-602. PMID 15062082 DOI: 10.1016/j.str.2004.03.003 |
0.448 |
|
| 2004 |
Ito N, Nureki O, Shirouzu M, Yokoyama S, Hanaoka F. Crystal structure of the Pyrococcus horikoshii DNA primase-UTP complex: implications for the mechanism of primer synthesis. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 8: 913-23. PMID 14750947 DOI: 10.1111/j.1365-2443.2003.00693.x |
0.382 |
|
| 2004 |
Sengoku T, Nureki O, Dohmae N, Nakamura A, Yokoyama S. Crystallization and preliminary X-ray analysis of the helicase domains of Vasa complexed with RNA and an ATP analogue. Acta Crystallographica. Section D, Biological Crystallography. 60: 320-2. PMID 14747711 DOI: 10.1107/S0907444903025897 |
0.424 |
|
| 2004 |
Kise Y, Lee SW, Park SG, Fukai S, Sengoku T, Ishii R, Yokoyama S, Kim S, Nureki O. A short peptide insertion crucial for angiostatic activity of human tryptophanyl-tRNA synthetase. Nature Structural & Molecular Biology. 11: 149-56. PMID 14730354 DOI: 10.1038/nsmb722 |
0.414 |
|
| 2004 |
Fujikawa N, Kurumizaka H, Nureki O, Tanaka Y, Yamazoe M, Hiraga S, Yokoyama S. Structural and biochemical analyses of hemimethylated DNA binding by the SeqA protein. Nucleic Acids Research. 32: 82-92. PMID 14704346 DOI: 10.1093/nar/gkh173 |
0.404 |
|
| 2004 |
Fukunaga R, Fukai S, Ishitani R, Nureki O, Yokoyama S. Crystal structures of the CP1 domain from Thermus thermophilus isoleucyl-tRNA synthetase and its complex with L-valine. The Journal of Biological Chemistry. 279: 8396-402. PMID 14672940 DOI: 10.1074/Jbc.M312830200 |
0.409 |
|
| 2003 |
Okabe M, Tomita K, Ishitani R, Ishii R, Takeuchi N, Arisaka F, Nureki O, Yokoyama S. Divergent evolutions of trinucleotide polymerization revealed by an archaeal CCA-adding enzyme structure. The Embo Journal. 22: 5918-27. PMID 14592988 DOI: 10.1093/Emboj/Cdg563 |
0.382 |
|
| 2003 |
Polycarpo C, Ambrogelly A, Ruan B, Tumbula-Hansen D, Ataide SF, Ishitani R, Yokoyama S, Nureki O, Ibba M, Söll D. Activation of the pyrrolysine suppressor tRNA requires formation of a ternary complex with class I and class II lysyl-tRNA synthetases. Molecular Cell. 12: 287-94. PMID 14536069 DOI: 10.1016/S1097-2765(03)00280-6 |
0.361 |
|
| 2003 |
Tawaramoto MS, Park SY, Tanaka Y, Nureki O, Kurumizaka H, Yokoyama S. Crystal structure of the human centromere protein B (CENP-B) dimerization domain at 1.65-A resolution. The Journal of Biological Chemistry. 278: 51454-61. PMID 14522975 DOI: 10.1074/jbc.M310388200 |
0.385 |
|
| 2003 |
Kigawa T, Yamaguchi-Nunokawa E, Kodama K, Matsuda T, Yabuki T, Matsuda N, Ishitani R, Nureki O, Yokoyama S. Selenomethionine incorporation into a protein by cell-free synthesis. Journal of Structural and Functional Genomics. 2: 29-35. PMID 12836672 DOI: 10.1023/a:1013203532303 |
0.386 |
|
| 2003 |
Kobayashi T, Nureki O, Ishitani R, Yaremchuk A, Tukalo M, Cusack S, Sakamoto K, Yokoyama S. Structural basis for orthogonal tRNA specificities of tyrosyl-tRNA synthetases for genetic code expansion. Nature Structural Biology. 10: 425-32. PMID 12754495 DOI: 10.2142/Biophys.43.S94_1 |
0.42 |
|
| 2003 |
Ishii R, Nureki O, Yokoyama S. Crystal structure of the tRNA processing enzyme RNase PH from Aquifex aeolicus. The Journal of Biological Chemistry. 278: 32397-404. PMID 12746447 DOI: 10.1074/jbc.M300639200 |
0.428 |
|
| 2003 |
Ishitani R, Nureki O, Nameki N, Okada N, Nishimura S, Yokoyama S. Alternative tertiary structure of tRNA for recognition by a posttranscriptional modification enzyme. Cell. 113: 383-94. PMID 12732145 DOI: 10.1016/s0092-8674(03)00280-0 |
0.439 |
|
| 2003 |
Fujikawa N, Kurumizaka H, Nureki O, Terada T, Shirouzu M, Katayama T, Yokoyama S. Structural basis of replication origin recognition by the DnaA protein. Nucleic Acids Research. 31: 2077-86. PMID 12682358 DOI: 10.1093/nar/gkg309 |
0.421 |
|
| 2003 |
Fukai S, Nureki O, Sekine S, Shimada A, Vassylyev DG, Yokoyama S. Mechanism of molecular interactions for tRNA(Val) recognition by valyl-tRNA synthetase. Rna (New York, N.Y.). 9: 100-11. PMID 12554880 DOI: 10.1261/rna.2760703 |
0.415 |
|
| 2003 |
Sekine S, Nureki O, Dubois DY, Bernier S, Chênevert R, Lapointe J, Vassylyev DG, Yokoyama S. ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding. The Embo Journal. 22: 676-88. PMID 12554668 DOI: 10.1093/Emboj/Cdg053 |
0.404 |
|
| 2002 |
Ogiso H, Ishitani R, Nureki O, Fukai S, Yamanaka M, Kim JH, Saito K, Sakamoto A, Inoue M, Shirouzu M, Yokoyama S. Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains. Cell. 110: 775-87. PMID 12297050 DOI: 10.1016/S0092-8674(02)00963-7 |
0.397 |
|
| 2002 |
Kagawa W, Kurumizaka H, Ishitani R, Fukai S, Nureki O, Shibata T, Yokoyama S. Crystal structure of the homologous-pairing domain from the human Rad52 recombinase in the undecameric form. Molecular Cell. 10: 359-71. PMID 12191481 DOI: 10.1016/s1097-2765(02)00587-7 |
0.404 |
|
| 2002 |
Nureki O, Shirouzu M, Hashimoto K, Ishitani R, Terada T, Tamakoshi M, Oshima T, Chijimatsu M, Takio K, Vassylyev DG, Shibata T, Inoue Y, Kuramitsu S, Yokoyama S. An enzyme with a deep trefoil knot for the active-site architecture. Acta Crystallographica. Section D, Biological Crystallography. 58: 1129-37. PMID 12077432 DOI: 10.1107/s0907444902006601 |
0.44 |
|
| 2002 |
Ishitani R, Nureki O, Fukai S, Kijimoto T, Nameki N, Watanabe M, Kondo H, Sekine M, Okada N, Nishimura S, Yokoyama S. Crystal structure of archaeosine tRNA-guanine transglycosylase. Journal of Molecular Biology. 318: 665-77. PMID 12054814 DOI: 10.1016/S0022-2836(02)00090-6 |
0.487 |
|
| 2002 |
Terada T, Nureki O, Ishitani R, Ambrogelly A, Ibba M, Söll D, Yokoyama S. Functional convergence of two lysyl-tRNA synthetases with unrelated topologies. Nature Structural Biology. 9: 257-62. PMID 11887185 DOI: 10.1038/Nsb777 |
0.414 |
|
| 2002 |
Hendrickson TL, Nomanbhoy TK, De Crécy-Lagard V, Fukai S, Nureki O, Yokoyama S, Schimmel P. Mutational separation of two pathways for editing by a class I tRNA synthetase Molecular Cell. 9: 353-362. PMID 11864608 DOI: 10.1016/S1097-2765(02)00449-5 |
0.391 |
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