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Nathan T. Jui, Ph.D. - Publications

Affiliations: 
Chemistry Emory University, Atlanta, GA 
Website:
https://scholarblogs.emory.edu/juigroup/
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26/43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hendy CM, Pratt CJ, Jui NT, Blakey SB. Defluoroalkylation of Trifluoromethylarenes with Hydrazones: Rapid Access to Benzylic Difluoroarylethylamines. Organic Letters. 25: 1397-1402. PMID 36848497 DOI: 10.1021/acs.orglett.3c00126  0.701
2022 Maust MC, Hendy CM, Jui NT, Blakey SB. Switchable Regioselective 6- or 5- Radical Cyclization via Photoredox Catalysis. Journal of the American Chemical Society. PMID 35200024 DOI: 10.1021/jacs.2c00192  0.649
2021 McDaniel KA, Blood AR, Smith GC, Jui NT. Dearomatization of Unactivated Arenes via Catalytic Hydroalkylation. Acs Catalysis. 11: 4968-4972. PMID 34367722 DOI: 10.1021/acscatal.1c00732  0.4
2021 Spurlin RM, Harris AL, Pratt CJ, Jui NT. Synthesis of Spirocyclic Piperidines by Radical Hydroarylation. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 32: 211-214. PMID 34326573 DOI: 10.1055/a-1315-1014  0.739
2021 McDaniel KA, Jui NT. Dearomatization through Photoredox Hydroarylation: Discovery of a Radical-Polar Crossover Strategy. Organic Letters. 23: 5576-5580. PMID 34232663 DOI: 10.1021/acs.orglett.1c02006  0.438
2021 McDaniel KA, Jui NT. Dearomatization through Photoredox Hydroarylation: Discovery of a Radical-Polar Crossover Strategy. Organic Letters. 23: 5576-5580. PMID 34232663 DOI: 10.1021/acs.orglett.1c02006  0.438
2021 Hendy CM, Smith GC, Xu Z, Lian T, Jui NT. Radical Chain Reduction via Carbon Dioxide Radical Anion (CO). Journal of the American Chemical Society. PMID 34102836 DOI: 10.1021/jacs.1c04427  0.42
2020 Flynn AR, McDaniel K, Hughes M, Vogt D, Jui NT. Hydroarylation of Arenes via Reductive Radical-Polar Crossover. Journal of the American Chemical Society. PMID 32379445 DOI: 10.1021/jacs.0c03926  0.377
2020 Pratt CJ, Aycock RA, King MD, Jui NT. Radical α-C-H Cyclobutylation of Aniline Derivatives. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 31: 51-54. PMID 32103861 DOI: 10.1055/s-0039-1690197  0.734
2019 Seath CP, Jui NT. Intermolecular Reactions of Pyridyl Radicals with Olefins via Photoredox Catalysis. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 30: 1607-1614. PMID 31938012 DOI: 10.1055/s-0037-1611527  0.425
2019 Vogt DB, Seath CP, Wang H, Jui NT. Selective C-F Functionalization of Unactivated Trifluoromethylarenes. Journal of the American Chemical Society. PMID 31369264 DOI: 10.1021/Jacs.9B06004  0.425
2019 Boyington AJ, Seath CP, Zearfoss AM, Xu Z, Jui NT. A Catalytic Strategy for Regioselective Arylethylamine Synthesis. Journal of the American Chemical Society. PMID 30759339 DOI: 10.1021/jacs.9b01077  0.382
2018 Seath CP, Vogt DB, Xu Z, Boyington AJ, Jui NT. Radical Hydroarylation of Functionalized Olefins and Mechanistic Investigation of Photocatalytic Pyridyl Radical Reactions. Journal of the American Chemical Society. PMID 30354095 DOI: 10.1021/jacs.8b10238  0.41
2018 Aycock RA, Pratt CJ, Jui NT. Aminoalkyl Radicals as Powerful Intermediates for the Synthesis of Unnatural Amino Acids and Peptides Acs Catalysis. 8: 9115-9119. DOI: 10.1021/acscatal.8b03031  0.7
2017 Wang H, Jui NT. Catalytic Defluoroalkylation of Trifluoromethylaromatics with Unactivated Alkenes. Journal of the American Chemical Society. PMID 29256607 DOI: 10.1021/Jacs.7B12590  0.416
2017 Aycock RA, Wang H, Jui NT. A mild catalytic system for radical conjugate addition of nitrogen heterocycles. Chemical Science. 8: 3121-3125. PMID 28507687 DOI: 10.1039/C7Sc00243B  0.397
2017 Boyington AJ, Riu MY, Jui NT. Anti-Markovnikov Hydroarylation of Unactivated Olefins via Pyridyl Radical Intermediates. Journal of the American Chemical Society. PMID 28472584 DOI: 10.1021/jacs.7b03262  0.407
2014 Ernst JB, Tay NE, Jui NT, Buchwald SL. Regioselective synthesis of benzimidazolones via cascade C-N coupling of monosubstituted ureas. Organic Letters. 16: 3844-6. PMID 24971635 DOI: 10.1021/Ol501531Q  0.552
2013 Tardiff DF, Jui NT, Khurana V, Tambe MA, Thompson ML, Chung CY, Kamadurai HB, Kim HT, Lancaster AK, Caldwell KA, Caldwell GA, Rochet JC, Buchwald SL, Lindquist S. Yeast reveal a "druggable" Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neurons. Science (New York, N.Y.). 342: 979-83. PMID 24158909 DOI: 10.1126/Science.1245321  0.439
2013 Chung CY, Khurana V, Auluck PK, Tardiff DF, Mazzulli JR, Soldner F, Baru V, Lou Y, Freyzon Y, Cho S, Mungenast AE, Muffat J, Mitalipova M, Pluth MD, Jui NT, et al. Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons. Science (New York, N.Y.). 342: 983-7. PMID 24158904 DOI: 10.1126/Science.1245296  0.4
2013 Jui NT, Buchwald SL. Cascade palladium catalysis: a predictable and selectable regiocontrolled synthesis of N-arylbenzimidazoles. Angewandte Chemie (International Ed. in English). 52: 11624-7. PMID 24038854 DOI: 10.1002/Anie.201306007  0.552
2012 Jui NT, Garber JA, Finelli FG, MacMillan DW. Enantioselective organo-SOMO cycloadditions: a catalytic approach to complex pyrrolidines from olefins and aldehydes. Journal of the American Chemical Society. 134: 11400-3. PMID 22764834 DOI: 10.1021/Ja305076B  0.77
2010 Jui NT, Lee ECY, MacMillan DWC. Enantioselective organo-SOMO cascade cycloadditions: A rapid approach to molecular complexity from simple aldehydes and olefins Journal of the American Chemical Society. 132: 10015-10017. PMID 20593858 DOI: 10.1021/Ja104313X  0.576
2008 Graham TH, Jones CM, Jui NT, MacMillan DW. Enantioselective organo-singly occupied molecular orbital catalysis: the carbo-oxidation of styrenes. Journal of the American Chemical Society. 130: 16494-5. PMID 19049447 DOI: 10.1021/Ja8075633  0.76
2007 Nasveschuk CG, Frein JD, Jui NT, Rovis T. A diastereoselective intermolecular heck reaction of 1,3-dioxepins. Organic Letters. 9: 5099-102. PMID 17958436 DOI: 10.1021/Ol702294U  0.586
2006 Nasveschuk CG, Jui NT, Rovis T. A modular approach to the synthesis of 2,3,4-trisubstituted tetrahydrofurans. Chemical Communications (Cambridge, England). 3119-21. PMID 16855705 DOI: 10.1039/B605438B  0.58
Low-probability matches (unlikely to be authored by this person)
2017 Aycock RA, Vogt DB, Jui NT. A practical and scalable system for heteroaryl amino acid synthesis. Chemical Science. 8: 7998-8003. PMID 29619169 DOI: 10.1039/c7sc03612d  0.295
2017 Tardiff DF, Brown LE, Yan X, Trilles R, Jui NT, Barrasa MI, Caldwell KA, Caldwell GA, Schaus SE, Lindquist S. Dihydropyrimidine-thiones and clioquinol synergize to target β-amyloid cellular pathologies through a metal-dependent mechanism. Acs Chemical Neuroscience. PMID 28628299 DOI: 10.1021/Acschemneuro.7B00187  0.256
2020 Cornelison JL, Cato ML, Johnson AM, D'Agostino EH, Melchers D, Patel AB, Mays SG, Houtman R, Ortlund EA, Jui NT. Development of a new class of liver receptor homolog-1 (LRH-1) agonists by photoredox conjugate addition. Bioorganic & Medicinal Chemistry Letters. 30: 127293. PMID 32631515 DOI: 10.1016/J.Bmcl.2020.127293  0.101
2016 Mays SG, Okafor CD, Whitby RJ, Goswami D, Stec JO, Flynn AR, Dugan MC, Jui NT, Griffin PR, Ortlund EA. Crystal Structures of the Nuclear Receptor, Liver Receptor Homolog 1, Bound to Synthetic Agonists Reveal a Novel Mechanism of Activation. The Journal of Biological Chemistry. PMID 27694446 DOI: 10.1074/Jbc.M116.753541  0.082
2023 Cato ML, D'Agostino EH, Spurlin RM, Flynn AR, Cornelison JL, Johnson AM, Fujita RA, Abraham SM, Jui NT, Ortlund EA. Comparison of Activity, Structure, and Dynamics of SF-1 and LRH-1 Complexed with Small Molecule Modulators. The Journal of Biological Chemistry. 104921. PMID 37328104 DOI: 10.1016/j.jbc.2023.104921  0.068
2023 Kelvin JM, Chimenti ML, Zhang DY, Williams EK, Moore SG, Humber GM, Baxter TA, Birnbaum LA, Qui M, Zecca H, Thapa A, Jain J, Jui NT, Wang X, Fu H, et al. Development of constitutively synergistic nanoformulations to enhance chemosensitivity in T-cell leukemia. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 37543290 DOI: 10.1016/j.jconrel.2023.07.045  0.066
2020 D'Agostino EH, Flynn AR, Cornelison JL, Mays SG, Patel A, Jui NT, Ortlund EA. Development of a Versatile and Sensitive Direct Ligand Binding Assay for Human NR5A Nuclear Receptors. Acs Medicinal Chemistry Letters. 11: 365-370. PMID 32184971 DOI: 10.1021/Acsmedchemlett.9B00442  0.061
2022 Cato ML, Cornelison JL, Spurlin RM, Courouble VV, Patel AB, Flynn AR, Johnson AM, Okafor CD, Frank F, D'Agostino EH, Griffin PR, Jui NT, Ortlund EA. Differential Modulation of Nuclear Receptor LRH-1 through Targeting Buried and Surface Regions of the Binding Pocket. Journal of Medicinal Chemistry. PMID 35503419 DOI: 10.1021/acs.jmedchem.2c00235  0.06
2022 Mays SG, D'Agostino EH, Flynn AR, Huang X, Wang G, Liu X, Millings EJ, Okafor CD, Patel A, Cato ML, Cornelison JL, Melchers D, Houtman R, Moore DD, Calvert JW, ... Jui NT, et al. A phospholipid mimetic targeting LRH-1 ameliorates colitis. Cell Chemical Biology. PMID 35316658 DOI: 10.1016/j.chembiol.2022.03.001  0.056
2017 Giroud C, Du Y, Marin M, Min Q, Jui NT, Fu H, Melikyan GB. Screening and Functional Profiling of Small-Molecule HIV-1 Entry and Fusion Inhibitors. Assay and Drug Development Technologies. 15: 53-63. PMID 28322598 DOI: 10.1089/Adt.2017.777  0.053
2023 Kelvin JM, Jain J, Thapa A, Qui M, Birnbaum LA, Moore SG, Zecca H, Summers RJ, Costanza E, Uricoli B, Wang X, Jui NT, Fu H, Du Y, DeRyckere D, et al. Constitutively synergistic multiagent drug formulations targeting MERTK, FLT3, and BCL-2 for treatment of AML. Biorxiv : the Preprint Server For Biology. PMID 36993676 DOI: 10.1101/2023.03.13.531236  0.05
2019 Mays S, Flynn AR, Cornelison J, Okafor CD, Wang H, Wang G, Huang X, Donaldson H, Millings E, Polavarapu R, Moore D, Calvert J, Jui NT, Ortlund EA. Development of the first low nanomolar Liver Receptor Homolog-1 agonist through structure-guided design. Journal of Medicinal Chemistry. PMID 31419141 DOI: 10.1021/Acs.Jmedchem.9B00753  0.042
2018 Flynn AR, Mays SG, Ortlund EA, Jui NT. Development of Hybrid Phospholipid Mimics as Effective Agonists for Liver Receptor Homologue-1. Acs Medicinal Chemistry Letters. 9: 1051-1056. PMID 30344916 DOI: 10.1021/Acsmedchemlett.8B00361  0.038
2023 Kelvin JM, Jain J, Thapa A, Qui M, Birnbaum LA, Moore SG, Zecca H, Summers RJ, Switchenko JM, Costanza E, Uricoli B, Wang X, Jui NT, Fu H, Du Y, et al. Constitutively Synergistic Multiagent Drug Formulations Targeting MERTK, FLT3, and BCL-2 for Treatment of AML. Pharmaceutical Research. PMID 37704893 DOI: 10.1007/s11095-023-03596-9  0.037
2022 Cato ML, Spurlin R, Cornelison J, Jui N, Ortlund E. Development and Characterization of Novel LRH-1 Antagonist Using Structural and Computational Techniques. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 35555641 DOI: 10.1096/fasebj.2022.36.S1.R4855  0.029
2017 Mays SG, Okafor CD, Whitby RJ, Goswami D, Stec J, Flynn AR, Dugan MC, Jui NT, Griffin PR, Ortlund EA. Targeting the nuclear receptor LRH-1 with synthetic agonists Acta Crystallographica Section a Foundations and Advances. 73: a98-a98. DOI: 10.1107/S0108767317099020  0.019
2020 Cato ML, Cornelison J, Flynn A, D’Agostino E, Jui N, Ortlund E. Development of picomolar liver receptor homolog‐1 agonist The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02884  0.01
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