Richard DiMarchi - Publications

Affiliations: 
Chemistry Indiana University, Bloomington, Bloomington, IN, United States 
Area:
endocrinology, specifically diabetes
Website:
http://dimarchi.chem.indiana.edu/

164 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Holland J, Sorrell J, Yates E, Smith K, Arbabi S, Arnold M, Rivir M, Morano R, Chen J, Zhang X, Dimarchi R, Woods SC, Sanchez-Gurmaches J, Wohleb E, Perez-Tilve D. A Brain-Melanocortin-Vagus Axis Mediates Adipose Tissue Expansion Independently of Energy Intake. Cell Reports. 27: 2399-2410.e6. PMID 31116984 DOI: 10.1016/j.celrep.2019.04.089  0.48
2019 He R, Finan B, Mayer JP, DiMarchi RD. Peptide Conjugates with Small Molecules Designed to Enhance Efficacy and Safety. Molecules (Basel, Switzerland). 24. PMID 31091786 DOI: 10.3390/molecules24101855  0.52
2019 Décarie-Spain L, Fisette A, Zhu Z, Yang B, DiMarchi RD, Tschöp MH, Finan B, Fulton S, Clemmensen C. GLP-1/dexamethasone inhibits food reward without inducing mood and memory deficits in mice. Neuropharmacology. PMID 30946847 DOI: 10.1016/j.neuropharm.2019.03.035  0.48
2019 Ratner C, He Z, Grunddal KV, Skov LJ, Hartmann B, Zhang F, Feuchtinger A, Bjerregaard A, Christoffersen C, Tschöp MH, Finan B, DiMarchi RD, Leinninger GM, Williams KW, Clemmensen C, et al. Long Acting Neurotensin Synergizes with Liraglutide to Reverse Obesity Through a Melanocortin-Dependent Pathway. Diabetes. PMID 30936142 DOI: 10.2337/db18-1009  0.48
2019 Bethea M, Liu Y, Wade AK, Mullen R, Gupta R, Gelfanov V, DiMarchi R, Bhatnagar S, Behringer R, Habegger KM, Hunter CS. The islet-expressed Lhx1 transcription factor interacts with Islet-1 and contributes to glucose homeostasis. American Journal of Physiology. Endocrinology and Metabolism. PMID 30620636 DOI: 10.1152/ajpendo.00235.2018  0.32
2018 Mroz PA, Finan B, Gelfanov V, Yang B, Tschöp MH, DiMarchi RD, Perez-Tilve D. Optimized GIP analogs promote body weight lowering in mice through GIPR agonism not antagonism. Molecular Metabolism. PMID 30578168 DOI: 10.1016/j.molmet.2018.12.001  0.56
2018 Clemmensen C, Finan B, Müller TD, DiMarchi RD, Tschöp MH, Hofmann SM. Emerging hormonal-based combination pharmacotherapies for the treatment of metabolic diseases. Nature Reviews. Endocrinology. PMID 30446744 DOI: 10.1038/s41574-018-0118-x  0.48
2018 Zhang F, Mayer J, Gelfanov V, Liu F, DiMarchi R. Structurally Constrained Insulin Analogs by Directed Stepwise Cross-linking. Protein and Peptide Letters. PMID 30381053 DOI: 10.2174/0929866525666181101103500  0.72
2018 Brandt SJ, Müller TD, DiMarchi RD, Tschöp MH, Stemmer K. Peptide-based multi-agonists: a new paradigm in metabolic pharmacology. Journal of Internal Medicine. PMID 30230640 DOI: 10.1111/joim.12837  0.48
2018 Rivero-Gutierrez B, Haller A, Holland J, Yates E, Khrisna R, Habegger K, Dimarchi R, D'Alessio D, Perez-Tilve D. Deletion of the glucagon receptor gene before and after experimental diabetes reveals differential protection from hyperglycemia. Molecular Metabolism. PMID 30170980 DOI: 10.1016/j.molmet.2018.07.012  0.48
2018 Kim T, Holleman CL, Nason S, Arble DM, Ottaway N, Chabenne J, Loyd C, Kim JA, Sandoval D, Drucker DJ, DiMarchi R, Perez-Tilve D, Habegger KM. Hepatic Glucagon-Receptor Signaling Enhances Insulin-Stimulated Glucose Disposal in Rodents. Diabetes. PMID 30150304 DOI: 10.2337/db18-0068  0.48
2018 Khajavi N, Finan B, Kluth O, Müller TD, Mergler S, Schulz A, Kleinau G, Scheerer P, Schürmann A, Gudermann T, Tschöp MH, Krude H, DiMarchi RD, Biebermann H. An incretin-based tri-agonist promotes superior insulin secretion from murine pancreatic islets via PLC activation. Cellular Signalling. 51: 13-22. PMID 30055232 DOI: 10.1016/j.cellsig.2018.07.006  0.48
2018 Renner S, Blutke A, Dobenecker B, Dhom G, Müller TD, Finan B, Clemmensen C, Bernau M, Novak I, Rathkolb B, Senf S, Zöls S, Roth M, Götz A, Hofmann SM, ... ... DiMarchi R, et al. Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Göttingen minipigs. Molecular Metabolism. PMID 30017782 DOI: 10.1016/j.molmet.2018.06.015  0.48
2018 Kim T, Nason S, Holleman C, Pepin M, Wilson L, Berryhill TF, Wende AR, Steele C, Young ME, Barnes S, Drucker DJ, Finan B, DiMarchi R, Perez-Tilve D, Tschoep M, et al. Glucagon-receptor Signaling Regulates Energy Metabolism Via Hepatic Farnesoid X Receptor and Fibroblast Growth Factor 21. Diabetes. PMID 29925501 DOI: 10.2337/db17-1502  0.56
2018 Capozzi ME, DiMarchi RD, Tschöp MH, Finan B, Campbell JE. Targeting the Incretin/Glucagon System with Triagonists to Treat Diabetes. Endocrine Reviews. PMID 29905825 DOI: 10.1210/er.2018-00117  0.48
2018 Zaykov AN, Gelfanov VM, Liu F, DiMarchi RD. High-Yield Synthesis of Human Insulin-Like Peptide 5 Employing a Nonconventional Strategy. Organic Letters. PMID 29874090 DOI: 10.1021/acs.orglett.8b01501  0.84
2018 Agrawal A, Parlee S, Perez-Tilve D, Li P, Pan J, Mroz PA, Kruse Hansen AM, Andersen B, Finan B, Kharitonenkov A, DiMarchi RD. Molecular elements in FGF19 and FGF21 defining KLB/FGFR activity and specificity. Molecular Metabolism. PMID 29789271 DOI: 10.1016/j.molmet.2018.05.003  0.56
2018 Altindis E, Cai W, Sakaguchi M, Zhang F, GuoXiao W, Liu F, De Meyts P, Gelfanov V, Pan H, DiMarchi R, Kahn CR. Viral insulin-like peptides activate human insulin and IGF-1 receptor signaling: A paradigm shift for host-microbe interactions. Proceedings of the National Academy of Sciences of the United States of America. PMID 29467286 DOI: 10.1073/pnas.1721117115  0.72
2018 Zaykov A, Gelfanov V, Liu F, DiMarchi RD, DiMarchi RD. Synthesis and Characterization of the R27S Genetic Variant of Insulin-like Peptide 5. Chemmedchem. PMID 29466617 DOI: 10.1002/cmdc.201800057  0.72
2018 Brandt SJ, Mayer JP, Ford J, Gelfanov VM, DiMarchi RD. Controlled intramolecular antagonism as a regulator of insulin receptor maximal activity. Peptides. 100: 18-23. PMID 29412818 DOI: 10.1016/j.peptides.2017.11.022  0.84
2018 DiMarchi RD, Mayer JP, Gelfanov VM, Tschöp M. Max Bergmann award lecture:Macromolecular medicinal chemistry as applied to metabolic diseases. Journal of Peptide Science : An Official Publication of the European Peptide Society. 24. PMID 29322647 DOI: 10.1002/psc.3056  0.84
2017 Knerr PJ, Finan B, Gelfanov V, Perez-Tilve D, Tschöp MH, DiMarchi RD. Optimization of peptide-based polyagonists for treatment of diabetes and obesity. Bioorganic & Medicinal Chemistry. PMID 29153547 DOI: 10.1016/j.bmc.2017.10.047  0.56
2017 Girada SB, Kuna RS, Bele S, Zhu Z, Chakravarthi NR, DiMarchi RD, Mitra P. Gαs regulates Glucagon-Like Peptide 1 Receptor-mediated cyclic AMP generation at Rab5 endosomal compartment. Molecular Metabolism. 6: 1173-1185. PMID 29031718 DOI: 10.1016/j.molmet.2017.08.002  0.32
2017 Kleinert M, Clemmensen C, Stemmer K, Müller TD, DiMarchi RD, Tschöp MH. Emerging Poly-Agonists for Obesity and Type 2 Diabetes. Obesity (Silver Spring, Md.). 25: 1647-1649. PMID 28948717 DOI: 10.1002/oby.21932  0.48
2017 Quarta C, Clemmensen C, Zhu Z, Yang B, Joseph SS, Lutter D, Yi CX, Graf E, García-Cáceres C, Legutko B, Fischer K, Brommage R, Zizzari P, Franklin BS, Krueger M, ... ... DiMarchi RD, et al. Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity. Cell Metabolism. PMID 28943448 DOI: 10.1016/j.cmet.2017.08.023  0.56
2017 Liu F, Li P, Gelfanov V, Mayer J, DiMarchi R. Synthetic Advances in Insulin-like Peptides Enable Novel Bioactivity. Accounts of Chemical Research. PMID 28771323 DOI: 10.1021/acs.accounts.7b00227  0.72
2017 Frias JP, Bastyr EJ, Vignati L, Tschöp MH, Schmitt C, Owen K, Christensen RH, DiMarchi RD. The Sustained Effects of a Dual GIP/GLP-1 Receptor Agonist, NNC0090-2746, in Patients with Type 2 Diabetes. Cell Metabolism. 26: 343-352.e2. PMID 28768173 DOI: 10.1016/j.cmet.2017.07.011  0.48
2017 Mayer JP, Tschöp MH, DiMarchi RD. Once Blind, Now We See GLP-1 Molecular Action. Cell Metabolism. 26: 289-291. PMID 28768169 DOI: 10.1016/j.cmet.2017.07.014  0.52
2017 Sánchez-Garrido MA, Brandt SJ, Clemmensen C, Müller TD, DiMarchi RD, Tschöp MH. GLP-1/glucagon receptor co-agonism for treatment of obesity. Diabetologia. PMID 28733905 DOI: 10.1007/s00125-017-4354-8  0.48
2017 Thalluri K, Kou B, Yang X, Zaykov AN, Mayer JP, Gelfanov VM, Liu F, DiMarchi RD. Synthesis of relaxin-2 and insulin-like peptide 5 enabled by novel tethering and traceless chemical excision. Journal of Peptide Science : An Official Publication of the European Peptide Society. PMID 28466571 DOI: 10.1002/psc.3010  0.84
2017 Jall S, Sachs S, Clemmensen C, Finan B, Neff F, DiMarchi RD, Tschöp MH, Müller TD, Hofmann SM. Monomeric GLP-1/GIP/glucagon triagonism corrects obesity, hepatosteatosis, and dyslipidemia in female mice. Molecular Metabolism. 6: 440-446. PMID 28462078 DOI: 10.1016/j.molmet.2017.02.002  0.48
2017 Wu F, Mayer JP, Gelfanov VG, Liu F, DiMarchi RD. Synthesis of Four-Disulfide Insulin Analogs via Sequential Disulfide Bond Formation. The Journal of Organic Chemistry. PMID 28319665 DOI: 10.1021/acs.joc.6b03078  0.72
2017 Thalluri K, Kou B, Gelfanov V, Mayer JP, Liu F, DiMarchi RD. Biomimetic Synthesis of Insulin Enabled by Oxime Ligation and Traceless "C-Peptide" Chemical Excision. Organic Letters. PMID 28124920 DOI: 10.1021/acs.orglett.6b03876  0.72
2016 Mroz PA, Perez-Tilve D, Liu F, Mayer JP, DiMarchi RD. Native design of soluble, aggregation-resistant bioactive peptides: Chemical evolution of human glucagon. Acs Chemical Biology. PMID 27797473 DOI: 10.1021/acschembio.6b00923  0.72
2016 Yang X, Gelfanov V, Liu F, DiMarchi R. Synthetic Route to Human Relaxin-2 via Iodine-Free Sequential Disulfide Bond Formation. Organic Letters. PMID 27754694 DOI: 10.1021/acs.orglett.6b02751  0.72
2016 Finan B, Clemmensen C, Zhu Z, Stemmer K, Gauthier K, Müller L, De Angelis M, Moreth K, Neff F, Perez-Tilve D, Fischer K, Lutter D, Sánchez-Garrido MA, Liu P, Tuckermann J, ... ... DiMarchi R, et al. Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease. Cell. PMID 27720451 DOI: 10.1016/j.cell.2016.09.014  0.72
2016 Sánchez-Garrido MA, Habegger KM, Clemmensen C, Holleman C, Müller TD, Perez-Tilve D, Li P, Agrawal AS, Finan B, Drucker DJ, Tschöp MH, DiMarchi RD, Kharitonenkov A. Fibroblast activation protein (FAP) as a novel metabolic target. Molecular Metabolism. 5: 1015-24. PMID 27689014 DOI: 10.1016/j.molmet.2016.07.003  0.56
2016 Mroz PA, Perez-Tilve D, Liu F, Gelfanov V, DiMarchi RD, Mayer JP. Pyridyl-alanine as a Hydrophilic, Aromatic Element in Peptide Structural Optimization. Journal of Medicinal Chemistry. PMID 27509198 DOI: 10.1021/acs.jmedchem.6b00840  0.72
2016 Vogel H, Wolf S, Rabasa C, Rodriguez-Pacheco F, Babaei CS, Stöber F, Goldschmidt J, DiMarchi RD, Finan B, Tschöp MH, Dickson SL, Schürmann A, Skibicka KP. GLP-1 and estrogen conjugate acts in the supramammillary nucleus to reduce food-reward and body weight. Neuropharmacology. PMID 27496691 DOI: 10.1016/j.neuropharm.2016.07.039  1
2016 Tschöp MH, Finan B, Clemmensen C, Gelfanov V, Perez-Tilve D, Müller TD, DiMarchi RD. Unimolecular Polypharmacy for Treatment of Diabetes and Obesity. Cell Metabolism. 24: 51-62. PMID 27411008 DOI: 10.1016/j.cmet.2016.06.021  0.56
2016 Wu F, Mayer JP, Zaykov AN, Zhang F, Liu F, DiMarchi RD. Chemical Synthesis of Human Insulin-Like Peptide-6. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27259101 DOI: 10.1002/chem.201601410  0.72
2016 Zaykov AN, Mayer JP, DiMarchi RD. Pursuit of a perfect insulin. Nature Reviews. Drug Discovery. PMID 26988411 DOI: 10.1038/nrd.2015.36  1
2016 Liu F, Zaykov AN, Levy JJ, DiMarchi RD, Mayer JP. Chemical synthesis of peptides within the insulin superfamily. Journal of Peptide Science : An Official Publication of the European Peptide Society. PMID 26910514 DOI: 10.1002/psc.2863  1
2015 Kharitonenkov A, DiMarchi R. FGF21 Revolutions: Recent Advances Illuminating FGF21 Biology and Medicinal Properties. Trends in Endocrinology and Metabolism: Tem. 26: 608-17. PMID 26490383 DOI: 10.1016/j.tem.2015.09.007  1
2015 Heppner KM, Marks S, Holland J, Ottaway N, Smiley D, Dimarchi R, Perez-Tilve D. Contribution of brown adipose tissue activity to the control of energy balance by GLP-1 receptor signalling in mice. Diabetologia. 58: 2124-32. PMID 26049402 DOI: 10.1007/s00125-015-3651-3  0.48
2015 Clemmensen C, Müller TD, Finan B, Tschöp MH, DiMarchi R. Current and Emerging Treatment Options in Diabetes Care. Handbook of Experimental Pharmacology. PMID 25903416 DOI: 10.1007/164_2015_7  1
2015 Hoover SE, Perez AJ, Tsui HC, Sinha D, Smiley DL, DiMarchi RD, Winkler ME, Lazazzera BA. A new quorum-sensing system (TprA/PhrA) for Streptococcus pneumoniae D39 that regulates a lantibiotic biosynthesis gene cluster. Molecular Microbiology. 97: 229-43. PMID 25869931 DOI: 10.1111/mmi.13029  1
2015 Wu F, Chabenne JR, Gelfanov VM, Mayer JP, DiMarchi RD. Three-chain insulin analogs demonstrate the importance of insulin secondary structure to bioactivity. Journal of Peptide Science : An Official Publication of the European Peptide Society. 21: 223-30. PMID 25665061 DOI: 10.1002/psc.2744  1
2015 Schwenk RW, Baumeier C, Finan B, Kluth O, Brauer C, Joost HG, DiMarchi RD, Tschöp MH, Schürmann A. GLP-1-oestrogen attenuates hyperphagia and protects from beta cell failure in diabetes-prone New Zealand obese (NZO) mice. Diabetologia. 58: 604-14. PMID 25527001 DOI: 10.1007/s00125-014-3478-3  0.48
2015 Finan B, Yang B, Ottaway N, Smiley DL, Ma T, Clemmensen C, Chabenne J, Zhang L, Habegger KM, Fischer K, Campbell JE, Sandoval D, Seeley RJ, Bleicher K, Uhles S, ... ... DiMarchi RD, et al. A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents. Nature Medicine. 21: 27-36. PMID 25485909 DOI: 10.1038/nm.3761  1
2015 Tiano JP, Tate CR, Yang BS, Dimarchi R, Mauvais-Jarvis F. Effect of targeted estrogen delivery using glucagon-like peptide-1 on insulin secretion, insulin sensitivity and glucose homeostasis Scientific Reports. 5. DOI: 10.1038/srep10211  1
2015 Heppner KM, Marks S, Holland J, Ottaway N, Smiley D, Dimarchi R, Perez-Tilve D. Contribution of brown adipose tissue activity to the control of energy balance by GLP-1 receptor signalling in mice Diabetologia. DOI: 10.1007/s00125-015-3651-3  1
2015 Müller TD, Clemmensen C, Finan B, Dimarchi RD, Tschöp MH. Novel combinatorial therapies involving leptin: Opportunities for mechanistic advances and therapeutic translation in human diseases Leptin: Regulation and Clinical Applications. 267-279. DOI: 10.1007/978-3-319-09915-6_21  1
2014 Kharitonenkov A, Dimarchi R. Break on through to the other 1 Cell Metabolism. 20: 554-555. PMID 25295781 DOI: 10.1016/j.cmet.2014.09.009  1
2014 Cao X, Xu P, Oyola MG, Xia Y, Yan X, Saito K, Zou F, Wang C, Yang Y, Hinton A, Yan C, Ding H, Zhu L, Yu L, Yang B, ... ... DiMarchi R, et al. Estrogens stimulate serotonin neurons to inhibit binge-like eating in mice. The Journal of Clinical Investigation. 124: 4351-62. PMID 25157819 DOI: 10.1172/JCI74726  1
2014 Chabenne J, Chabenne MD, Zhao Y, Levy J, Smiley D, Gelfanov V, Dimarchi R. A glucagon analog chemically stabilized for immediate treatment of life-threatening hypoglycemia. Molecular Metabolism. 3: 293-300. PMID 24749059 DOI: 10.1016/j.molmet.2014.01.006  1
2014 Clemmensen C, Chabenne J, Finan B, Sullivan L, Fischer K, Küchler D, Sehrer L, Ograjsek T, Hofmann SM, Schriever SC, Pfluger PT, Pinkstaff J, Tschöp MH, Dimarchi R, Müller TD. GLP-1/glucagon coagonism restores leptin responsiveness in obese mice chronically maintained on an obesogenic diet. Diabetes. 63: 1422-7. PMID 24379349 DOI: 10.2337/db13-1609  1
2014 Zaykov AN, Mayer JP, Gelfanov VM, DiMarchi RD. Chemical synthesis of insulin analogs through a novel precursor. Acs Chemical Biology. 9: 683-91. PMID 24328449 DOI: 10.1021/cb400792s  1
2014 Habegger KM, Heppner KM, Amburgy SE, Ottaway N, Holland J, Raver C, Bartley E, Müller TD, Pfluger PT, Berger J, Toure M, Benoit SC, Dimarchi RD, Perez-Tilve D, D'Alessio DA, et al. GLP-1R responsiveness predicts individual gastric bypass efficacy on glucose tolerance in rats. Diabetes. 63: 505-13. PMID 24186863 DOI: 10.2337/db13-0511  1
2014 Heppner KM, Piechowski CL, Müller A, Ottaway N, Sisley S, Smiley DL, Habegger KM, Pfluger PT, Dimarchi R, Biebermann H, Tschöp MH, Sandoval DA, Perez-Tilve D. Both acyl and des-acyl ghrelin regulate adiposity and glucose metabolism via central nervous system ghrelin receptors. Diabetes. 63: 122-31. PMID 24062249 DOI: 10.2337/db13-0414  0.48
2014 Heppner KM, Piechowski CL, Müller A, Ottaway N, Sisley S, Smiley DL, Habegger KM, Pfluger PT, DiMarchi R, Biebermann H, Tschöp MH, Sandoval DA, Perez-Tilve D. Both acyl and des-acyl ghrelin regulate adiposity and glucose metabolism via central nervous system ghrelin receptors Diabetes. 63: 122-131. DOI: 10.2337/db13-0414  1
2014 Schwenk RW, Baumeier C, Finan B, Kluth O, Brauer C, Joost HG, DiMarchi RD, Tschöp MH, Schürmann A. GLP-1–oestrogen attenuates hyperphagia and protects from beta cell failure in diabetes-prone New Zealand obese (NZO) mice Diabetologia. 58: 604-614. DOI: 10.1007/s00125-014-3478-3  1
2013 Ward BP, Ottaway NL, Perez-Tilve D, Ma D, Gelfanov VM, Tschöp MH, Dimarchi RD. Peptide lipidation stabilizes structure to enhance biological function. Molecular Metabolism. 2: 468-79. PMID 24327962 DOI: 10.1016/j.molmet.2013.08.008  0.84
2013 Patterson JT, Li P, Day JW, Gelfanov VM, Dimarchi RD. A hydrophobic site on the GLP-1 receptor extracellular domain orients the peptide ligand for signal transduction. Molecular Metabolism. 2: 86-91. PMID 24199154 DOI: 10.1016/j.molmet.2013.01.003  1
2013 Finan B, Ma T, Ottaway N, Müller TD, Habegger KM, Heppner KM, Kirchner H, Holland J, Hembree J, Raver C, Lockie SH, Smiley DL, Gelfanov V, Yang B, Hofmann S, ... ... DiMarchi RD, et al. Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans Science Translational Medicine. 5. PMID 24174327 DOI: 10.1126/scitranslmed.3007218  1
2013 Habegger KM, Kirchner H, Yi CX, Heppner KM, Sweeney D, Ottaway N, Holland J, Amburgy S, Raver C, Krishna R, Müller TD, Perez-Tilve D, Pfluger PT, Obici S, DiMarchi RD, et al. GLP-1R agonism enhances adjustable gastric banding in diet-induced obese rats. Diabetes. 62: 3261-7. PMID 23775764 DOI: 10.2337/db13-0117  1
2013 Müller TD, Müller A, Yi CX, Habegger KM, Meyer CW, Gaylinn BD, Finan B, Heppner K, Trivedi C, Bielohuby M, Abplanalp W, Meyer F, Piechowski CL, Pratzka J, Stemmer K, ... ... DiMarchi R, et al. The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms. Nature Communications. 4: 1968. PMID 23744028 DOI: 10.1038/ncomms2968  1
2013 Kaur ZP, Ochman AR, Mayer JP, Gelfanov VM, DiMarchi RD. Discovery of high potency, single-chain insulin analogs with a shortened B-chain and nonpeptide linker. Acs Chemical Biology. 8: 1822-9. PMID 23730814 DOI: 10.1021/cb4002624  1
2013 Kuna RS, Girada SB, Asalla S, Vallentyne J, Maddika S, Patterson JT, Smiley DL, DiMarchi RD, Mitra P. Glucagon-like peptide-1 receptor-mediated endosomal cAMP generation promotes glucose-stimulated insulin secretion in pancreatic β-cells. American Journal of Physiology. Endocrinology and Metabolism. 305: E161-70. PMID 23592482 DOI: 10.1152/ajpendo.00551.2012  1
2013 Campanello GC, Ma Z, Grossoehme NE, Guerra AJ, Ward BP, Dimarchi RD, Ye Y, Dann CE, Giedroc DP. Allosteric inhibition of a zinc-sensing transcriptional repressor: Insights into the arsenic repressor (ArsR) family Journal of Molecular Biology. 425: 1143-1157. PMID 23353829 DOI: 10.1016/j.jmb.2013.01.018  1
2013 Habegger KM, Stemmer K, Cheng C, Müller TD, Heppner KM, Ottaway N, Holland J, Hembree JL, Smiley D, Gelfanov V, Krishna R, Arafat AM, Konkar A, Belli S, Kapps M, ... ... DiMarchi RD, et al. Fibroblast growth factor 21 mediates specific glucagon actions. Diabetes. 62: 1453-63. PMID 23305646 DOI: 10.2337/db12-1116  1
2013 Ward BP, Ottaway NL, Perez-Tilve D, Ma D, Gelfanov VM, Tschöp MH, DiMarchi RD. Peptide lipidation stabilizes structure to enhance biological function Molecular Metabolism. 2: 468-479. DOI: 10.1016/j.molmet.2013.08.008  1
2012 Day JW, Gelfanov V, Smiley D, Carrington PE, Eiermann G, Chicchi G, Erion MD, Gidda J, Thornberry NA, Tschöp MH, Marsh DJ, SinhaRoy R, DiMarchi R, Pocai A. Optimization of co-agonism at GLP-1 and glucagon receptors to safely maximize weight reduction in DIO-rodents. Biopolymers. 98: 443-50. PMID 23203689 DOI: 10.1002/bip.22072  1
2012 Finan B, Yang B, Ottaway N, Stemmer K, Müller TD, Yi CX, Habegger K, Schriever SC, García-Cáceres C, Kabra DG, Hembree J, Holland J, Raver C, Seeley RJ, Hans W, ... ... DiMarchi RD, et al. Targeted estrogen delivery reverses the metabolic syndrome. Nature Medicine. 18: 1847-56. PMID 23142820 DOI: 10.1038/nm.3009  1
2012 Lockie SH, Heppner KM, Chaudhary N, Chabenne JR, Morgan DA, Veyrat-Durebex C, Ananthakrishnan G, Rohner-Jeanrenaud F, Drucker DJ, DiMarchi R, Rahmouni K, Oldfield BJ, Tschöp MH, Perez-Tilve D. Direct control of brown adipose tissue thermogenesis by central nervous system glucagon-like peptide-1 receptor signaling Diabetes. 61: 2753-2762. PMID 22933116 DOI: 10.2337/db11-1556  1
2012 Heppner KM, Chaudhary N, Müller TD, Kirchner H, Habegger KM, Ottaway N, Smiley DL, Dimarchi R, Hofmann SM, Woods SC, Sivertsen B, Holst B, Pfluger PT, Perez-Tilve D, Tschöp MH. Acylation type determines ghrelin's effects on energy homeostasis in rodents. Endocrinology. 153: 4687-95. PMID 22865372 DOI: 10.1210/en.2012-1194  1
2012 Tschöp MH, DiMarchi RD. Outstanding scientific achievement award lecture 2011: Defeating diabesity - The case for personalized combinatorial therapies Diabetes. 61: 1309-1314. PMID 22618765 DOI: 10.2337/db12-0272  1
2012 Müller TD, Sullivan LM, Habegger K, Yi CX, Kabra D, Grant E, Ottaway N, Krishna R, Holland J, Hembree J, Perez-Tilve D, Pfluger PT, DeGuzman MJ, Siladi ME, Kraynov VS, ... ... DiMarchi R, et al. Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21. Journal of Peptide Science : An Official Publication of the European Peptide Society. 18: 383-93. PMID 22565812 DOI: 10.1002/psc.2408  1
2012 Mu J, Pinkstaff J, Li Z, Skidmore L, Li N, Myler H, Dallas-Yang Q, Putnam AM, Yao J, Bussell S, Wu M, Norman TC, Rodriguez CG, Kimmel B, Metzger JM, ... ... DiMarchi RD, et al. FGF21 analogs of sustained action enabled by orthogonal biosynthesis demonstrate enhanced antidiabetic pharmacology in rodents. Diabetes. 61: 505-12. PMID 22210323 DOI: 10.2337/db11-0838  1
2011 Patterson JT, Day JW, Gelfanov VM, DiMarchi RD. Functional association of the N-terminal residues with the central region in glucagon-related peptides. Journal of Peptide Science : An Official Publication of the European Peptide Society. 17: 659-66. PMID 21661079 DOI: 10.1002/psc.1385  1
2011 Cho H, Daniel T, Buechler YJ, Litzinger DC, Maio Z, Putnam AM, Kraynov VS, Sim BC, Bussell S, Javahishvili T, Kaphle S, Viramontes G, Ong M, Chu S, Becky GC, ... ... DiMarchi RD, et al. Optimized clinical performance of growth hormone with an expanded genetic code. Proceedings of the National Academy of Sciences of the United States of America. 108: 9060-5. PMID 21576502 DOI: 10.1073/pnas.1100387108  1
2011 Wiedmer P, Strasser F, Horvath TL, Blum D, Dimarchi R, Lutz T, Schürmann A, Joost HG, Tschöp MH, Tong J. Ghrelin-induced hypothermia: a physiological basis but no clinical risk. Physiology & Behavior. 105: 43-51. PMID 21513721 DOI: 10.1016/j.physbeh.2011.03.027  1
2011 Day JW, Li P, Patterson JT, Chabenne J, Chabenne MD, Gelfanov VM, Dimarchi RD. Charge inversion at position 68 of the glucagon and glucagon-like peptide-1 receptors supports selectivity in hormone action. Journal of Peptide Science : An Official Publication of the European Peptide Society. 17: 218-25. PMID 21308878 DOI: 10.1002/psc.1317  1
2011 Patterson JT, Ottaway N, Gelfanov VM, Smiley DL, Perez-Tilve D, Pfluger PT, Tschöp MH, Dimarchi RD. A novel human-based receptor antagonist of sustained action reveals body weight control by endogenous GLP-1. Acs Chemical Biology. 6: 135-45. PMID 20939591 DOI: 10.1021/cb1002015  1
2010 Chabenne JR, DiMarchi MA, Gelfanov VM, DiMarchi RD. Optimization of the native glucagon sequence for medicinal purposes Journal of Diabetes Science and Technology. 4: 1322-1331. PMID 21129326  1
2010 Ward WK, Massoud RG, Szybala CJ, Engle JM, El Youssef J, Carroll JM, Roberts CT, DiMarchi RD. In vitro and in vivo evaluation of native glucagon and glucagon analog (MAR-D28) during aging: lack of cytotoxicity and preservation of hyperglycemic effect. Journal of Diabetes Science and Technology. 4: 1311-21. PMID 21129325  1
2010 Habegger KM, Heppner KM, Geary N, Bartness TJ, DiMarchi R, Tschöp MH. The metabolic actions of glucagon revisited. Nature Reviews. Endocrinology. 6: 689-97. PMID 20957001 DOI: 10.1038/nrendo.2010.187  0.48
2010 Bohrer BC, Li YF, Reilly JP, Clemmer DE, DiMarchi RD, Radivojac P, Tang H, Arnold RJ. Combinatorial libraries of synthetic peptides as a model for shotgun proteomics. Analytical Chemistry. 82: 6559-68. PMID 20669997 DOI: 10.1021/ac100910a  1
2010 De A, DiMarchi RD. Synthesis and characterization of ester-based prodrugs of glucagon-like peptide 1. Biopolymers. 94: 448-56. PMID 20593470 DOI: 10.1002/bip.21418  1
2010 Perez-Tilve D, Hofmann SM, Basford J, Nogueiras R, Pfluger PT, Patterson JT, Grant E, Wilson-Perez HE, Granholm NA, Arnold M, Trevaskis JL, Butler AA, Davidson WS, Woods SC, Benoit SC, ... ... DiMarchi RD, et al. Melanocortin signaling in the CNS directly regulates circulating cholesterol. Nature Neuroscience. 13: 877-82. PMID 20526334 DOI: 10.1038/nn.2569  1
2010 Heppner KM, Habegger KM, Day J, Pfluger PT, Perez-Tilve D, Ward B, Gelfanov V, Woods SC, DiMarchi R, Tschöp M. Glucagon regulation of energy metabolism. Physiology & Behavior. 100: 545-8. PMID 20381509 DOI: 10.1016/j.physbeh.2010.03.019  1
2009 Ma Z, Cowart DM, Ward BP, Arnold RJ, DiMarchi RD, Zhang L, George GN, Scott RA, Giedroc DP. Unnatural amino acid substitution as a probe of the allosteric coupling pathway in a mycobacterial Cu(I) sensor Journal of the American Chemical Society. 131: 18044-18045. PMID 19928961 DOI: 10.1021/ja908372b  1
2009 Andrews ZB, Erion D, Beiler R, Liu ZW, Abizaid A, Zigman J, Elsworth JD, Savitt JM, DiMarchi R, Tschoep M, Roth RH, Gao XB, Horvath TL. Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14057-65. PMID 19906954 DOI: 10.1523/JNEUROSCI.3890-09.2009  1
2009 Day JW, Ottaway N, Patterson JT, Gelfanov V, Smiley D, Gidda J, Findeisen H, Bruemmer D, Drucker DJ, Chaudhary N, Holland J, Hembree J, Abplanalp W, Grant E, Ruehl J, ... ... DiMarchi R, et al. A new glucagon and GLP-1 co-agonist eliminates obesity in rodents. Nature Chemical Biology. 5: 749-57. PMID 19597507 DOI: 10.1038/nchembio.209  1
2009 Nogueiras R, Pérez-Tilve D, Veyrat-Durebex C, Morgan DA, Varela L, Haynes WG, Patterson JT, Disse E, Pfluger PT, López M, Woods SC, DiMarchi R, Diéguez C, Rahmouni K, Rohner-Jeanrenaud F, et al. Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 5916-25. PMID 19420258 DOI: 10.1523/JNEUROSCI.5977-08.2009  1
2009 Cantel S, Halperin JA, Chorev M, Scrima M, D'Ursi AM, Levy JJ, Dimarchi RD, Chevalier AL, Rovero P, Papini AM. Side chain-to-side chain cyclization by intramolecular click reaction - Building blocks, solid phase synthesis and conformational characterization Advances in Experimental Medicine and Biology. 611: 175-176. PMID 19400147 DOI: 10.1007/978-0-387-73657-0_80  1
2008 Cantel S, Isaad ALC, Scrima M, Levy JJ, DiMarchi RD, Rovero P, Halperin JA, D'Ursi AM, Papini AM, Chorev M. Synthesis and conformational analysis of a cyclic peptide obtained via i to i+4 intramolecular side-chain to side-chain azide-alkyne 1,3-dipolar cycloaddition Journal of Organic Chemistry. 73: 5663-5674. PMID 18489158 DOI: 10.1021/jo800142s  1
2008 Li P, Rogers T, Smiley D, DiMarchi RD, Zhang F. Crystallization and preliminary x-ray analysis of anti-obesity peptide hormone oxyntomodulin Protein and Peptide Letters. 15: 232-234. PMID 18289117  1
2008 De A, DiMarchi RD. Investigation of the feasibility of an amide-based prodrug under physiological conditions (International Journal of Peptide Research and Therapeutics DOI: 10.1007/s10989-008-9141-4) International Journal of Peptide Research and Therapeutics. 14: 393. DOI: 10.1007/s10989-008-9152-1  1
2008 De A, DiMarchi RD. Investigation of the feasibily of an amide-based prodrug under physiological conditions International Journal of Peptide Research and Therapeutics. 14: 255-262. DOI: 10.1007/s10989-008-9141-4  1
2007 Li P, Rogers T, Smiley D, DiMarchi RD, Zhang F. Design, synthesis and crystallization of a novel glucagon analog as a therapeutic agent Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 63: 599-601. PMID 17620721 DOI: 10.1107/S1744309107028655  1
2007 Yan LZ, Hsiung HM, Heiman ML, Gadski RA, Emmerson PJ, Hertel J, Flora D, Edwards P, Smiley D, Zhang L, Husain S, Kahl SD, DiMarchi RD, Mayer JP. Structure-activity relationships of β-MSH derived melanocortin-4 receptor peptide agonists Current Topics in Medicinal Chemistry. 7: 1052-1067. PMID 17584126 DOI: 10.2174/156802607780906591  1
2007 Mayer JP, Zhang F, DiMarchi RD. Insulin structure and function Biopolymers - Peptide Science Section. 88: 687-713. PMID 17410596 DOI: 10.1002/bip.20734  1
2007 Kohn WD, Micanovic R, Myers SL, Vick AM, Kahl SD, Zhang L, Strifler BA, Li S, Shang J, Beals JM, Mayer JP, DiMarchi RD. pI-shifted insulin analogs with extended in vivo time action and favorable receptor selectivity. Peptides. 28: 935-48. PMID 17328992 DOI: 10.1016/j.peptides.2007.01.012  1
2007 Nogueiras R, Pfluger P, Tovar S, Arnold M, Mitchell S, Morris A, Perez-Tilve D, Vázquez MJ, Wiedmer P, Castañeda TR, DiMarchi R, Tschöp M, Schurmann A, Joost HG, Williams LM, et al. Effects of obestatin on energy balance and growth hormone secretion in rodents. Endocrinology. 148: 21-6. PMID 17008393 DOI: 10.1210/en.2006-0915  1
2006 Gabet Y, Müller R, Levy J, Dimarchi R, Chorev M, Bab I, Kohavi D. Parathyroid hormone 1-34 enhances titanium implant anchorage in low-density trabecular bone: A correlative micro-computed tomographic and biomechanical analysis Bone. 39: 276-282. PMID 16617039 DOI: 10.1016/j.bone.2006.02.004  1
2005 Mayer JP, DiMarchi RD. Drugging the undruggable Chemistry and Biology. 12: 860-861. PMID 16125095 DOI: 10.1016/j.chembiol.2005.08.004  1
2005 Zhang F, Chen Y, Heiman M, DiMarchi R. Leptin: Structure, Function and Biology Vitamins and Hormones. 71: 345-372. PMID 16112274 DOI: 10.1016/S0083-6729(05)71012-8  1
2005 Yan LZ, Flora D, Edwards P, Smiley DL, Emmerson PJ, Hsiung HM, Gadski R, Hertel J, Heiman ML, Husain S, O'Brien TP, Kahl SD, Zhang L, DiMarchi RD, Mayer JP. Potent and selective MC-4 receptor agonists based on a novel disulfide scaffold Bioorganic and Medicinal Chemistry Letters. 15: 4611-4614. PMID 16105738 DOI: 10.1016/j.bmcl.2005.06.081  1
2005 Mayer JP, Hsiung HM, Flora DB, Edwards P, Smith DP, Zhang XY, Gadski RA, Heiman ML, Hertel JL, Emmerson PJ, Husain S, O'brien TP, Kahl SD, Smiley DL, Zhang L, ... Dimarchi RD, et al. Discovery of a beta-MSH-derived MC-4R selective agonist. Journal of Medicinal Chemistry. 48: 3095-8. PMID 15857110 DOI: 10.1021/jm0501432  1
1999 Huster W, Shah A, Kaiser G, Dere W, DiMarchi R. Statistical and operational issues arising in an interim analysis when the study will continue Drug Information Journal. 33: 869-875.  1
1998 Radziuk J, Pye S, Bradley B, Braaten J, Vignati L, Roach P, Bowsher R, DiMarchi R, Chance R. Basal activity profiles of NPH and [N(ε)-palmitoyl Lys (B29)] human insulins in subjects with IDDM Diabetologia. 41: 116-120. PMID 9498640 DOI: 10.1007/s001250050876  1
1998 Chance RE, Frank BH, Radziuk JM, DiMarchi RD. Discovery and development of insulin lispro Drugs of Today. 34: 1-9.  1
1997 Slieker LJ, Brooke GS, Dimarchi RD, Flora DB, Green LK, Hoffmann JA, Long HB, Fan L, Shields JE, Sundell KL, Surface PL, Chance RE. Modifications in the B10 and B26-30 regions of the B chain of human insulin alter affinity for the human IGF-I receptor more than for the insulin receptor Diabetologia. 40: S54-S61. PMID 9248702 DOI: 10.1007/s001250051402  1
1997 Ido Y, Vindigni A, Chang K, Stramm L, Chance R, Heath WF, DiMarchi RD, Di Cera E, Williamson JR. Prevention of vascular and neural dysfunction in diabetic rats by C- peptide Science. 277: 563-566. PMID 9228006 DOI: 10.1126/science.277.5325.563  1
1997 Anderson JH, Brunelle RL, Keohane P, Koivisto VA, Trautmann ME, Vignati L, DiMarchi R. Mealtime treatment with insulin analog improves postprandial hyperglycemia and hypoglycemia in patients with non-insulin-dependent diabetes mellitus Archives of Internal Medicine. 157: 1249-1255. PMID 9183237  1
1997 Zhang F, Basinski MB, Beals JM, Briggs SL, Churgay LM, Clawson DK, DiMarchi RD, Furman TC, Hale JE, Hsiung HM, Schoner BE, Smith DP, Zhang XY, Wery JP, Schevitz RW. Crystal structure of the obese protein leptin-E100. Nature. 387: 206-9. PMID 9144295 DOI: 10.1038/387206a0  1
1997 Anderson JH, Brunelle RL, Koivisto VA, Trautmann ME, Vignati L, DiMarchi R, Cameron DP, Yeu DK, Zimmet P, Lauvaux JP, Van Gaal LF, Chiasson JL, Fettes IM, Tan MH, Toth EL, et al. Improved mealtime treatment of diabetes mellitus using an insulin analogue Clinical Therapeutics. 19: 62-72. PMID 9083709 DOI: 10.1016/S0149-2918(97)80073-2  1
1997 Radziuk JM, Davies JC, Pye WS, Shields JE, DiMarchi RD, Chance RE. Bioavailability and bioeffectiveness of subcutaneous human insulin and two of its analogs-Lys(B28)Pro(B29)-human insulin and Asp(B10)Lys(B28)Pro(B29)-human insulin-assessed in a conscious pig model Diabetes. 46: 548-556. PMID 9075793  1
1997 Anderson JH, Brunelle RL, Koivisto VA, Pfützner A, Trautmann ME, Vignati L, DiMarchi R. Reduction of postprandial hyperglycemia and frequency of hypoglycemia in IDDM patients on insulin-analog treatment Diabetes. 46: 265-270. PMID 9000704  1
1997 Basinski MB, DiMarchi RD, Flora DB, Heath WF, Hoffmann J, Schoner BE, Shields JE, Smiley DL. Anti-obesity proteins Biotechnology Advances. 15: 781.  1
1996 DiMarchi RD, Trautmann ME. Insulin lispro: Molecular structure and biological actions | INSULIN LISPRO: MOLEKULARSTRUKTUR UND BIOLOGISCHE WIRKUNGEN Diabetes Und Stoffwechsel. 5: 113-116.  1
1994 DiMarchi RD, Chance RE, Long HB, Shields JE, Slieker LJ. Preparation of an insulin with improved pharmacokinetics relative to human insulin through consideration of structural homology with insulin-like growth factor I Hormone Research. 41: 93-96. PMID 8088710 DOI: 10.1159/000183967  1
1994 Burguera B, Elton CW, Tapscott EB, Pories WJ, Dimarchi R, Sakano -i. K, Dohm GL. Stimulation of glucose uptake by insulin-like growth factor II in human muscle is not mediated by the insulin-like growth factor II/mannose 6-phosphate receptor Biochemical Journal. 300: 781-785. PMID 8010960  1
1994 Burguera B, Elton CW, Caro JF, Tapscott EB, Pories WJ, Dimarchi R, Sakano K, Dohm GL. Correction: Stimulation of glucose uptake by insulin-like growth factor II in human muscle is not mediated by the insulin-like growth factor II/mannose 6-phosphate receptor (Biochemical Journal (1994) 300 (781-785)) Biochemical Journal. 304: 1023.  1
1994 LeRoith D, DiMarchi RD. Editorial Hormone Research. 41: 49-50.  1
1993 Slieker LJ, Brooke GS, Chance RE, Fan L, Hoffmann JA, Howey DC, Long HB, Mayer J, Shields JE, Sundell KL, DiMarchi RD. Insulin and IGF-I analogs: Novel approaches to improved insulin pharmacokinetics Advances in Experimental Medicine and Biology. 343: 25-32. PMID 8184740  1
1992 Heath WF, Belagaje RM, Brooke GS, Chance RE, Hoffmann JA, Long HB, Reams SG, Roundtree C, Shaw WN, Slieker LJ, Sundell KL, DiMarchi RD. (A-C-B) human proinsulin, a novel insulin agonist and intermediate in the synthesis of biosynthetic human insulin Journal of Biological Chemistry. 267: 419-425. PMID 1730606  1
1992 Brems DN, Alter LA, Beckage MJ, Chance RE, DiMarchi RD, Green LK, Long HB, Pekar AH, Shields JE, Frank BH. Altering the association properties of insulin by amino acid replacement Protein Engineering. 5: 527-533. PMID 1438163 DOI: 10.1093/protein/5.6.527  1
1992 Flynn JN, Harkiss GD, Moore D, DiMarchi R. Modulation of T-cell reactivity to synthetic peptide analogues of foot-and-mouth disease virus in sheep by amino acid substitutions Veterinary Immunology and Immunopathology. 31: 255-266. PMID 1375405 DOI: 10.1016/0165-2427(92)90013-G  1
1992 Doel TR, Doel CMFA, Staple RF, DiMarchi R. Cross-reactive and serotype-specific antibodies against foot-and-mouth disease virus generated by different regions of the same synthetic peptide Journal of Virology. 66: 2187-2194. PMID 1372368  1
1992 Mulcahy G, Reid E, Dimarchi RD, Gale C, Doel TR. Maturation of functional antibody affinity in animals immunised with synthetic foot-and-mouth disease virus Research in Veterinary Science. 52: 133-140. PMID 1316628 DOI: 10.1016/0034-5288(92)90001-I  1
1992 Galloway JA, DiMarchi RD. International symposium addresses research and new directions in diabetes management: A report on a recent international conference Practical Diabetes. 9: 238.  1
1991 Broderick CL, Brooke GS, DiMarchi RD, Gold G. Human and rat amylin have no effects on insulin secretion in isolated rat pancreatic islets Biochemical and Biophysical Research Communications. 177: 932-938. PMID 2059220 DOI: 10.1016/0006-291X(91)90628-K  1
1991 Rossetti L, Frontoni S, Dimarchi R, DeFronzo RA, Giaccari A. Metabolic effects of IGF-I in diabetic rats Diabetes. 40: 444-448. PMID 2010044  1
1991 Owens RA, Gesellchen PD, Houchins BJ, DiMarchi RD. The rapid identification of HIV protease inhibitors through the synthesis and screening of defined peptide mixtures. Biochemical and Biophysical Research Communications. 181: 402-8. PMID 1958209 DOI: 10.1016/S0006-291X(05)81433-0  1
1991 Bodkin NL, Sportsman R, DiMarchi RD, Hansen BC. Insulin-like growth factor-I in non-insulin-dependent diabetic monkeys: Basal plasma concentrations and metabolic effects of exogenously administered biosynthetic hormone Metabolism. 40: 1131-1137. PMID 1943741 DOI: 10.1016/0026-0495(91)90206-C  1
1991 Burguera B, Frank BH, DiMarchi R, Long S, Caro JF. The interaction of proinsulin with the insulin-like growth factor-I receptor in human liver, muscle, and adipose tissue Journal of Clinical Endocrinology and Metabolism. 72: 1238-1241. PMID 1851182  1
1991 Mulcahy G, Pullen LA, Gale C, DiMarchi RD, Doel TR. Mouse protection test as a predictor of the protective capacity of synthetic foot-and-mouth disease vaccines Vaccine. 9: 19-24. PMID 1848960 DOI: 10.1016/0264-410X(91)90311-S  1
1991 Steward MW, Stanley CM, Dimarchi R, Mulcahy G, Doel TR. High-affinity antibody induced by immunization with a synthetic peptide is associated with protection of cattle against foot-and-mouth disease Immunology. 72: 99-103. PMID 1847695  1
1991 Kit S, Kit M, DiMarchi R, Little S, Gale C. Modified-live infectious bovine rhinotracheitis virus (IBRV) vaccine expressing foot-and-mouth disease virus (FMDV) capsid protein epitopes on surface of hybrid virus particles Advances in Experimental Medicine and Biology. 303: 211-220. PMID 1725233  1
1991 Kit S, Kit M, DiMarchi RD, Little SP, Gale C. Modified-live infectious bovine rhinotracheitis virus vaccine expressing monomer and dimer forms of foot-and-mouth disease capsid protein epitopes on surface of hybrid virus particles Archives of Virology. 120: 1-17. PMID 1718244 DOI: 10.1007/BF01310945  1
1991 Collen T, Dimarchi R, Doel TR. A T cell epitope in VP1 of foot-and-mouth disease virus is immunodominant for vaccinated cattle Journal of Immunology. 146: 749-755. PMID 1702816  1
1991 Glass EJ, Oliver RA, Collen T, Doel TR, Dimarchi R, Spooner RL. MHC class II restricted recognition of FMDV peptides by bovine T cells Immunology. 74: 594-599. PMID 1664415  1
1990 Dohm GL, Elton CW, Raju MS, Mooney ND, DiMarchi R, Pories WJ, Flickinger EG, Atkinson SM, Caro JF. IGF-I-stimulated glucose transport in human skeletal muscle and IGF-I resistance in obesity and NIDDM Diabetes. 39: 1028-1032. PMID 2166697  1
1990 Mulcahy G, Gale C, Robertson P, Iyisan S, DiMarchi RD, Doel TR. Isotype responses of infected, virus-vaccinated and peptide-vaccinated cattle to foot-and-mouth disease virus. Vaccine. 8: 249-56. PMID 2163575 DOI: 10.1016/0264-410X(90)90054-P  1
1990 Sinha MK, Buchanan C, Raineri-Maldonado C, Khazanie P, Atkinson S, DiMarchi R, Caro JF. IGF-II receptors and IGF-II-stimulated glucose transport in human fat cells. The American Journal of Physiology. 258: E534-42. PMID 2156441  1
1990 Heiman ML, Surface PL, Mowrey DH, DiMarchi RD. Sexual dimorphic porcine pituitary response to growth hormone-releasing hormone Domestic Animal Endocrinology. 7: 273-276. PMID 2114958 DOI: 10.1016/0739-7240(90)90033-V  1
1990 Flynn JN, Harkiss GD, Doel T, DiMarchi R. Analysis of immune responses in the sheep to synthetic peptides of foot-and-mouth disease virus using ovine polyclonal and monoclonal antibodies Immunology. 69: 1-7. PMID 1690176  1
1989 Schalch DS, Yang H, Ney DM, DiMarchi RD. Infusion of human insulin-like growth factor I (IGF-I) into malnourished rats reduces hepatic IGF-I mRNA abundance. Biochemical and Biophysical Research Communications. 160: 795-800. PMID 2719698 DOI: 10.1016/0006-291X(89)92503-5  1
1989 Gale C, Doel T, Brooke G, White D, Mulcahy G, DiMarchi R. Protection induced by synthetic peptides corresponding to three serotypes in foot and mouth disease virus. Advances in Experimental Medicine and Biology. 251: 161-7. PMID 2558525  1
1989 Sinha MK, Buchanan C, Leggett N, Martin L, Khazanie PG, Dimarchi R, Pories WJ, Caro JF. Mechanism of IGF-I-stimulated glucose transport in human adipocytes. Demonstration of specific IGF-I receptors not involved in stimulation of glucose transport. Diabetes. 38: 1217-25. PMID 2551760  1
1989 Thakker JK, DiMarchi R, MacDonald K, Caro JF. Effect of insulin and insulin-like growth factors I and II on phosphatidylinositol and phosphatidylinositol 4,5-bisphosphate breakdown in liver from humans with and without type II diabetes. The Journal of Biological Chemistry. 264: 7169-75. PMID 2540178  1
1988 Doel TR, Gale C, Brooke G, DiMarchi R. Immunization against foot-and-mouth disease with synthetic peptides representing the C-terminal region of VP1. The Journal of General Virology. 69: 2403-6. PMID 2457649 DOI: 10.1099/0022-1317-69-9-2403  1
1986 DiMarchi R, Brooke G, Gale C, Cracknell V, Doel T, Mowat N. Protection of cattle against foot-and-mouth disease by a synthetic peptide. Science (New York, N.Y.). 232: 639-41. PMID 3008333 DOI: 10.1126/science.3008333  1
1983 Voss C, Dimarchi R, Whitney DB, Tjoeng FS, Merrifield RB, Tam JP. Synthesis of the protected tridecapeptide (56-68) of the VH domain of mouse myeloma immunoglobulin M603 and its reattachment to resin supports. International Journal of Peptide and Protein Research. 22: 204-13. PMID 6618764  1
1982 Dimarchi RD, Tam JP, Kent SB, Merrifield RB. Weak acid-catalyzed pyrrolidone carboxylic acid formation from glutamine during solid phase peptide synthesis. Minimization by rapid coupling. International Journal of Peptide and Protein Research. 19: 88-93. PMID 7118385  1
1982 Dimarchi RD, Tam JP, Merrifield RB. Solid phase synthesis of the protected 43-55 tridecapeptide of the heavy chain of myeloma immunoglobin M603, employing cyclohexyl ester protection for glutamic acid. International Journal of Peptide and Protein Research. 19: 270-9. PMID 6811468  1
1981 Tam JP, DiMarchi RD, Merrifield RB. Design and synthesis of a multi-detachable benzhydrylamine-resin for solid phase peptide synthesis Tetrahedron Letters. 22: 2851-2854. DOI: 10.1016/S0040-4039(01)81767-6  1
1980 DiMarchi RD, Neireiter GW, Heath WF, Gurd FRN. Structural significance of the amino-terminal residues of sperm whale myoglobin Biochemistry. 19: 2454-2465. PMID 7387984  1
1980 Tam JP, Dimarchi RD, Merrifield RB. Photolabile multi-detachable p-alkoxybenzyl alcohol resin supports for peptide fragment or semi-synthesis. International Journal of Peptide and Protein Research. 16: 412-25. PMID 7216616  1
1979 DiMarchi RD, Neireiter GW, Garner WH, Gurd FRN. Myoglobin semisynthesis: Removal of the NH2-terminal valine of sperm whale myoglobin and its subsequent reincorporation Biochemistry. 18: 3101-3109. PMID 37895  1
1978 DiMarchi RD, Wang CC, Hemenway JB, Gurd FRN. Complete amino acid sequence of the major component myoglobin of finback whale (Balaenoptera physalus) Biochemistry. 17: 1968-1970. PMID 656375  1
1978 DiMarchi RD, Garner WH, Wang CC, Hanania GI, Gurd FR. Characterization of the reaction of methyl acetimidate with sperm whale myoglobin. Biochemistry. 17: 2822-8. PMID 28745  1
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