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Nathan A. Magarvey - Publications

Affiliations: 
Chemistry and Chemical Biology/Biochemistry and Biomedical Sciences McMaster University, Hamilton, ON, Canada 
Area:
natural products
Website:
http://fhs.mcmaster.ca/biochem/magarvey_nathan.html
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54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Merwin NJ, Mousa WK, Dejong CA, Skinnider MA, Cannon MJ, Li H, Dial K, Gunabalasingam M, Johnston C, Magarvey NA. DeepRiPP integrates multiomics data to automate discovery of novel ribosomally synthesized natural products. Proceedings of the National Academy of Sciences of the United States of America. PMID 31871149 DOI: 10.1073/Pnas.1901493116  0.445
2018 Skinnider MA, Johnston CW, Merwin NJ, Dejong CA, Magarvey NA. Global analysis of prokaryotic tRNA-derived cyclodipeptide biosynthesis. Bmc Genomics. 19: 45. PMID 29334896 DOI: 10.1186/S12864-018-4435-1  0.428
2017 Skinnider MA, Dejong CA, Franczak BC, McNicholas PD, Magarvey NA. Comparative analysis of chemical similarity methods for modular natural products with a hypothetical structure enumeration algorithm. Journal of Cheminformatics. 9: 46. PMID 29086195 DOI: 10.1186/S13321-017-0234-Y  0.39
2017 Mousa WK, Athar B, Merwin NJ, Magarvey NA. Antibiotics and specialized metabolites from the human microbiota. Natural Product Reports. PMID 29018846 DOI: 10.1039/C7Np00021A  0.342
2017 Skinnider MA, Merwin NJ, Johnston CW, Magarvey NA. PRISM 3: expanded prediction of natural product chemical structures from microbial genomes. Nucleic Acids Research. PMID 28460067 DOI: 10.1093/Nar/Gkx320  0.433
2017 Bernier SP, Hum C, Li X, O'Toole GA, Magarvey N, Surette MG. Pseudomonas aeruginosa-derived rhamnolipids and other detergents modulate colony morphotype and motility in the Burkholderia cepacia complex. Journal of Bacteriology. PMID 28439038 DOI: 10.1128/Jb.00171-17  0.318
2017 Williams DE, Dalisay DS, Chen J, Polishchuck EA, Patrick BO, Narula G, Ko M, Av-Gay Y, Li H, Magarvey N, Andersen RJ. Aminorifamycins and Sporalactams Produced in Culture by a Micromonospora sp. Isolated from a Northeastern-Pacific Marine Sediment Are Potent Antibiotics. Organic Letters. PMID 28164711 DOI: 10.1021/Acs.Orglett.6B03619  0.31
2016 Johnston CW, Plumb J, Li X, Grinstein S, Magarvey NA. Informatic analysis reveals Legionella as a source of novel natural products. Synthetic and Systems Biotechnology. 1: 130-136. PMID 29062936 DOI: 10.1016/J.Synbio.2015.12.001  0.445
2016 Skinnider MA, Johnston CW, Edgar RE, Dejong CA, Merwin NJ, Rees PN, Magarvey NA. Genomic charting of ribosomally synthesized natural product chemical space facilitates targeted mining. Proceedings of the National Academy of Sciences of the United States of America. PMID 27698135 DOI: 10.1073/Pnas.1609014113  0.449
2016 Dejong CA, Chen GM, Li H, Johnston CW, Edwards MR, Rees PN, Skinnider MA, Webster AL, Magarvey NA. Polyketide and nonribosomal peptide retro-biosynthesis and global gene cluster matching. Nature Chemical Biology. PMID 27694801 DOI: 10.1038/Nchembio.2188  0.394
2016 Caminero A, Galipeau HJ, McCarville JL, Johnston CW, Bernier SP, Russell AK, Jury J, Herran AR, Casqueiro J, Tye-Din JA, Surette MG, Magarvey NA, Schuppan D, Verdu EF. Duodenal bacteria from patients with celiac disease and healthy subjects distinctly affect gluten breakdown and immunogenicity. Gastroenterology. PMID 27373514 DOI: 10.1053/J.Gastro.2016.06.041  0.346
2016 Liu DY, Li Y, Magarvey NA. Draft Genome Sequence of Streptomyces canus ATCC 12647, a Producer of Telomycin. Genome Announcements. 4. PMID 27013049 DOI: 10.1128/Genomea.00173-16  0.369
2016 Johnston CW, Li Y, Magarvey NA. Draft Genome Sequence of Streptomyces silvensis ATCC 53525, a Producer of Novel Hormone Antagonists. Genome Announcements. 4. PMID 26893408 DOI: 10.1128/Genomea.00001-16  0.362
2016 Johnston CW, Skinnider MA, Dejong CA, Rees PN, Chen GM, Walker CG, French S, Brown ED, Bérdy J, Liu DY, Magarvey NA. Assembly and clustering of natural antibiotics guides target identification. Nature Chemical Biology. PMID 26829473 DOI: 10.1038/Nchembio.2018  0.401
2015 Epand RM, Walker C, Epand RF, Magarvey NA. Molecular mechanisms of membrane targeting antibiotics. Biochimica Et Biophysica Acta. PMID 26514603 DOI: 10.1016/J.Bbamem.2015.10.018  0.339
2015 Skinnider MA, Dejong CA, Rees PN, Johnston CW, Li H, Webster AL, Wyatt MA, Magarvey NA. Genomes to natural products PRediction Informatics for Secondary Metabolomes (PRISM). Nucleic Acids Research. PMID 26442528 DOI: 10.1093/Nar/Gkv1012  0.441
2015 Johnston CW, Skinnider MA, Wyatt MA, Li X, Ranieri MR, Yang L, Zechel DL, Ma B, Magarvey NA. An automated Genomes-to-Natural Products platform (GNP) for the discovery of modular natural products. Nature Communications. 6: 8421. PMID 26412281 DOI: 10.1038/Ncomms9421  0.436
2015 Yang L, Ibrahim A, Johnston CW, Skinnider MA, Ma B, Magarvey NA. Exploration of Nonribosomal Peptide Families with an Automated Informatic Search Algorithm. Chemistry & Biology. 22: 1259-69. PMID 26364933 DOI: 10.1016/J.Chembiol.2015.08.008  0.389
2015 Johnston CW, Connaty AD, Skinnider MA, Li Y, Grunwald A, Wyatt MA, Kerr RG, Magarvey NA. Informatic search strategies to discover analogues and variants of natural product archetypes. Journal of Industrial Microbiology & Biotechnology. PMID 26350080 DOI: 10.1007/S10295-015-1675-9  0.401
2015 Alonzo DA, Magarvey NA, Schmeing TM. Characterization of cereulide synthetase, a toxin-producing macromolecular machine. Plos One. 10: e0128569. PMID 26042597 DOI: 10.1371/Journal.Pone.0128569  0.403
2015 Johnston CW, Magarvey NA. Natural products: untwisting the antibiotic'ome. Nature Chemical Biology. 11: 177-8. PMID 25689333 DOI: 10.1038/Nchembio.1757  0.355
2015 Skinnider MA, Johnston CW, Zvanych R, Magarvey NA. Automated identification of depsipeptide natural products by an informatic search algorithm. Chembiochem : a European Journal of Chemical Biology. 16: 223-7. PMID 25487354 DOI: 10.1002/Cbic.201402434  0.432
2015 Zvanych R, Lukenda N, Li X, Kim JJ, Tharmarajah S, Magarvey NA. Systems biosynthesis of secondary metabolic pathways within the oral human microbiome member Streptococcus mutans. Molecular Biosystems. 11: 97-104. PMID 25209237 DOI: 10.1039/C4Mb00406J  0.434
2014 Zvanych R, Lukenda N, Kim JJ, Li X, Petrof EO, Khan WI, Magarvey NA. Small molecule immunomodulins from cultures of the human microbiome member Lactobacillus plantarum Journal of Antibiotics. 67: 85-88. PMID 24281660 DOI: 10.1038/Ja.2013.126  0.329
2014 Alonzo D, Reimer J, Magarvey N, Schmeing TM. Towards the structure of an unusual nonribosomal peptide synthetase Acta Crystallographica Section a Foundations and Advances. 70: C433-C433. DOI: 10.1107/S2053273314095667  0.403
2014 Ibrahim A, Yang L, Johnston C, Liu X, Ma B, Magarvey N. Informatic search for natural products (iSNAP) – A dereplication and discovery tool Planta Medica. 80. DOI: 10.1055/S-0034-1382669  0.339
2014 Wyatt MA, Johnston CW, Magarvey NA. Gold nanoparticle formation via microbial metallophore chemistries Journal of Nanoparticle Research. 16. DOI: 10.1007/S11051-013-2212-2  0.303
2013 Vanner SA, Li X, Zvanych R, Torchia J, Sang J, Andrews DW, Magarvey NA. Chemical and biosynthetic evolution of the antimycin-type depsipeptides. Molecular Biosystems. 9: 2712-9. PMID 23989727 DOI: 10.1039/C3Mb70219G  0.394
2013 Li X, Zvanych R, Vanner SA, Wang W, Magarvey NA. Chemical variation from the neoantimycin depsipeptide assembly line Bioorganic and Medicinal Chemistry Letters. 23: 5123-5127. PMID 23932359 DOI: 10.1016/J.Bmcl.2013.07.031  0.339
2013 Wyatt MA, Magarvey NA. Optimizing dimodular nonribosomal peptide synthetases and natural dipeptides in an Escherichia coli heterologous host Biochemistry and Cell Biology. 91: 203-208. PMID 23859013 DOI: 10.1139/Bcb-2012-0097  0.443
2013 Wyatt MA, Lee J, Ahilan Y, Magarvey NA. Bioinformatic evaluation of the secondary metabolism of antistaphylococcal environmental bacterial isolates Canadian Journal of Microbiology. 59: 465-471. PMID 23826955 DOI: 10.1139/Cjm-2013-0016  0.384
2013 Wyatt MA, Ahilan Y, Argyropoulos P, Boddy CN, Magarvey NA, Harrison PH. Biosynthesis of ebelactone A: isotopic tracer, advanced precursor and genetic studies reveal a thioesterase-independent cyclization to give a polyketide β-lactone. The Journal of Antibiotics. 66: 421-30. PMID 23801186 DOI: 10.1038/Ja.2013.48  0.335
2013 Li X, Vanner S, Wang W, Li Y, Gallardo VA, Magarvey NA. Macplocimine A, a new 18-membered macrolide isolated from the filamentous sulfur bacteria Thioploca sp. Journal of Antibiotics. 66: 443-446. PMID 23778115 DOI: 10.1038/Ja.2013.52  0.34
2013 Li X, Zvanych R, Torchia J, Magarvey NA. Structures and biosynthesis of 12-membered macrocyclic depsipeptides from Streptomyces sp. ML55 Bioorganic and Medicinal Chemistry Letters. 23: 4150-4153. PMID 23756369 DOI: 10.1016/J.Bmcl.2013.05.042  0.357
2013 Johnston CW, Zvanych R, Khyzha N, Magarvey NA. Nonribosomal assembly of natural lipocyclocarbamate lipoprotein-associated phospholipase inhibitors. Chembiochem : a European Journal of Chemical Biology. 14: 431-5. PMID 23401283 DOI: 10.1002/Cbic.201200598  0.356
2012 Ibrahim A, Yang L, Johnston C, Liu X, Ma B, Magarvey NA. Dereplicating nonribosomal peptides using an informatic search algorithm for natural products (iSNAP) discovery. Proceedings of the National Academy of Sciences of the United States of America. 109: 19196-201. PMID 23132949 DOI: 10.1073/Pnas.1206376109  0.415
2012 Wyatt MA, Mok MCY, Junop M, Magarvey NA. Heterologous Expression and Structural Characterisation of a Pyrazinone Natural Product Assembly Line Chembiochem. 13: 2408-2415. PMID 23070851 DOI: 10.1002/Cbic.201200340  0.399
2012 Wenderska IB, Lukenda N, Cordova M, Magarvey N, Cvitkovitch DG, Senadheera DB. A novel function for the competence inducing peptide, XIP, as a cell death effector of Streptococcus mutans Fems Microbiology Letters. 336: 104-112. PMID 22900705 DOI: 10.1111/J.1574-6968.2012.02660.X  0.328
2012 Johnston C, Ibrahim A, Magarvey N. Informatic strategies for the discovery of polyketides and nonribosomal peptides Medchemcomm. 3: 932-937. DOI: 10.1039/C2Md20120H  0.431
2011 Li J, Wang W, Xu SX, Magarvey NA, McCormick JK. Lactobacillus reuteri-produced cyclic dipeptides quench agr-mediated expression of toxic shock syndrome toxin-1 in staphylococci Proceedings of the National Academy of Sciences of the United States of America. 108: 3360-3365. PMID 21282650 DOI: 10.1073/Pnas.1017431108  0.309
2010 Wyatt MA, Wang W, Roux CM, Beasley FC, Heinrichs DE, Dunman PM, Magarvey NA. Staphylococcus aureus nonribosomal peptide secondary metabolites regulate virulence Science. 329: 294-296. PMID 20522739 DOI: 10.1126/Science.1188888  0.371
2008 Calderone CT, Bumpus SB, Kelleher NL, Walsh CT, Magarvey NA. A ketoreductase domain in the PksJ protein of the bacillaene assembly line carries out both alpha- and beta-ketone reduction during chain growth. Proceedings of the National Academy of Sciences of the United States of America. 105: 12809-14. PMID 18723688 DOI: 10.1073/Pnas.0806305105  0.544
2008 Bumpus SB, Magarvey NA, Kelleher NL, Walsh CT, Calderone CT. Polyunsaturated fatty-acid-like trans-enoyl reductases utilized in polyketide biosynthesis. Journal of the American Chemical Society. 130: 11614-6. PMID 18693732 DOI: 10.1021/Ja8040042  0.571
2008 Magarvey NA, Fortin PD, Thomas PM, Kelleher NL, Walsh CT. Gatekeeping versus promiscuity in the early stages of the andrimid biosynthetic assembly line. Acs Chemical Biology. 3: 542-54. PMID 18652473 DOI: 10.1021/Cb800085G  0.578
2007 Fortin PD, Walsh CT, Magarvey NA. A transglutaminase homologue as a condensation catalyst in antibiotic assembly lines. Nature. 448: 824-7. PMID 17653193 DOI: 10.1038/Nature06068  0.576
2006 Magarvey NA, Beck ZQ, Golakoti T, Ding Y, Huber U, Hemscheidt TK, Abelson D, Moore RE, Sherman DH. Biosynthetic characterization and chemoenzymatic assembly of the cryptophycins. Potent anticancer agents from cyanobionts. Acs Chemical Biology. 1: 766-79. PMID 17240975 DOI: 10.1021/Cb6004307  0.667
2006 Magarvey NA, Ehling-Schulz M, Walsh CT. Characterization of the cereulide NRPS alpha-hydroxy acid specifying modules: activation of alpha-keto acids and chiral reduction on the assembly line. Journal of the American Chemical Society. 128: 10698-9. PMID 16910662 DOI: 10.1021/Ja0640187  0.477
2006 Magarvey NA, Haltli B, He M, Greenstein M, Hucul JA. Biosynthetic pathway for mannopeptimycins, lipoglycopeptide antibiotics active against drug-resistant gram-positive pathogens Antimicrobial Agents and Chemotherapy. 50: 2167-2177. PMID 16723579 DOI: 10.1128/Aac.01545-05  0.518
2005 Haltli B, Tan Y, Magarvey NA, Wagenaar M, Yin X, Greenstein M, Hucul JA, Zabriskie TM. Investigating β-hydroxyenduracididine formation in the biosynthesis of the mannopeptimycins Chemistry and Biology. 12: 1163-1168. PMID 16298295 DOI: 10.1016/J.Chembiol.2005.09.013  0.363
2005 Beck ZQ, Aldrich CC, Magarvey NA, Georg GI, Sherman DH. Chemoenzymatic synthesis of cryptophycin/arenastatin natural products. Biochemistry. 44: 13457-66. PMID 16216069 DOI: 10.1021/Bi051140U  0.667
2004 Magarvey NA, Keller JM, Bernan V, Dworkin M, Sherman DH. Isolation and characterization of novel marine-derived actinomycete taxa rich in bioactive metabolites. Applied and Environmental Microbiology. 70: 7520-9. PMID 15574955 DOI: 10.1128/Aem.70.12.7520-7529.2004  0.537
2004 Salomon CE, Magarvey NA, Sherman DH. Merging the potential of microbial genetics with biological and chemical diversity: an even brighter future for marine natural product drug discovery. Natural Product Reports. 21: 105-21. PMID 15039838 DOI: 10.1039/B301384G  0.566
2001 He J, Magarvey N, Piraee M, Vining LC. The gene cluster for chloramphenicol biosynthesis in Streptomyces venezuelae ISP5230 includes novel shikimate pathway homologues and a monomodular non-ribosomal peptide synthetase gene Microbiology. 147: 2817-2829. PMID 11577160 DOI: 10.1099/00221287-147-10-2817  0.572
2001 Magarvey N, He J, Aidoo KA, Vining LC. The pdx genetic marker adjacent to the chloramphenicol biosynthesis gene cluster in Streptomyces venezuelae ISP5230: Functional characterization Microbiology. 147: 2103-2112. PMID 11495988  0.493
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