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William C. Merrick - Publications

Affiliations: 
Biochemistry Case Western Reserve University, Cleveland Heights, OH, United States 
Area:
eukaryotic translation initiation factors, initiation pathway
Website:
http://www.case.edu/med/biochemistry/faculty/merrick.html
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Year Citation  Score
2022 Krokowski D, Jobava R, Szkop KJ, Chen CW, Fu X, Venus S, Guan BJ, Wu J, Gao Z, Banaszuk W, Tchorzewski M, Mu T, Ropelewski P, Merrick WC, Mao Y, et al. Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR. Cell Reports. 40: 111092. PMID 35858571 DOI: 10.1016/j.celrep.2022.111092  0.316
2020 Lyons SM, Kharel P, Akiyama Y, Ojha S, Dave D, Tsvetkov V, Merrick W, Ivanov P, Anderson P. eIF4G has intrinsic G-quadruplex binding activity that is required for tiRNA function. Nucleic Acids Research. PMID 32374873 DOI: 10.1093/Nar/Gkaa336  0.412
2020 Komar AA, Merrick WC. A Retrospective on eIF2A-and Not the Alpha Subunit of eIF2. International Journal of Molecular Sciences. 21. PMID 32192132 DOI: 10.3390/Ijms21062054  0.536
2020 Chu J, Zhang W, Cencic R, O'Connor PBF, Robert F, Devine WG, Selznick A, Henkel T, Merrick WC, Brown LE, Baranov PV, Porco JA, Pelletier J. Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F. Cell Reports. PMID 32101697 DOI: 10.1016/J.Celrep.2020.02.002  0.331
2018 Merrick WC, Pavitt GD. Protein Synthesis Initiation in Eukaryotic Cells. Cold Spring Harbor Perspectives in Biology. PMID 29735639 DOI: 10.1101/Cshperspect.A033092  0.477
2017 Guan BJ, van Hoef V, Jobava R, Elroy-Stein O, Valasek LS, Cargnello M, Gao XH, Krokowski D, Merrick WC, Kimball SR, Komar AA, Koromilas AE, Wynshaw-Boris A, Topisirovic I, Larsson O, et al. A Unique ISR Program Determines Cellular Responses to Chronic Stress. Molecular Cell. 68: 885-900.e6. PMID 29220654 DOI: 10.1016/J.Molcel.2017.11.007  0.36
2016 Golovko A, Kojukhov A, Guan BJ, Morpurgo B, Merrick WC, Mazumder B, Hatzoglou M, Komar AA. The eIF2A knockout mouse. Cell Cycle (Georgetown, Tex.). 0. PMID 27686860 DOI: 10.1080/15384101.2016.1237324  0.462
2015 Carelli JD, Sethofer SG, Smith GA, Miller HR, Simard JL, Merrick WC, Jain RK, Ross NT, Taunton J. Ternatin and improved synthetic variants kill cancer cells by targeting the elongation factor-1A ternary complex. Elife. 4. PMID 26651998 DOI: 10.7554/Elife.10222  0.367
2015 Merrick WC. eIF4F: A Retrospective. The Journal of Biological Chemistry. 290: 24091-9. PMID 26324716 DOI: 10.1074/Jbc.R115.675280  0.478
2015 Chen H, Song R, Wang G, Ding Z, Yang C, Zhang J, Zeng Z, Rubio V, Wang L, Zu N, Weiskoff AM, Minze LJ, Jeyabal PV, Mansour OC, Bai L, ... Merrick WC, et al. OLA1 regulates protein synthesis and integrated stress response by inhibiting eIF2 ternary complex formation. Scientific Reports. 5: 13241. PMID 26283179 DOI: 10.1038/Srep13241  0.435
2015 Carelli JD, Sethofer SG, Smith GA, Miller HR, Simard JL, Merrick WC, Jain RK, Ross NT, Taunton J. Author response: Ternatin and improved synthetic variants kill cancer cells by targeting the elongation factor-1A ternary complex Elife. DOI: 10.7554/Elife.10222.027  0.305
2014 Khan MA, Ma J, Walden WE, Merrick WC, Theil EC, Goss DJ. Rapid kinetics of iron responsive element (IRE) RNA/iron regulatory protein 1 and IRE-RNA/eIF4F complexes respond differently to metal ions Nucleic Acids Research. 42: 6567-6577. PMID 24728987 DOI: 10.1093/Nar/Gku248  0.357
2014 Guan BJ, Krokowski D, Majumder M, Schmotzer CL, Kimball SR, Merrick WC, Koromilas AE, Hatzoglou M. Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eif2 Journal of Biological Chemistry. 289: 12593-12611. PMID 24648524 DOI: 10.1074/Jbc.M113.543215  0.432
2014 Merrick WC, Harris ME. Control not at initiation? Bah, humbug! Embo Journal. 33: 3-4. PMID 24363142 DOI: 10.1002/Embj.201387388  0.424
2013 Barth-Baus D, Bhasker CR, Zoll W, Merrick WC. Influence of translation factor activities on start site selection in six different mRNAs. Translation (Austin, Tex.). 1: e24419. PMID 26824019 DOI: 10.4161/trla.24419  0.404
2012 Jia M, Haldar S, Khan MA, Sharma SD, Merrick WC, Theil EC, Goss DJ. Fe2+ binds iron responsive element-RNA, selectively changing protein-binding affinities and regulating mRNA repression and activation Proceedings of the National Academy of Sciences of the United States of America. 109: 8417-8422. PMID 22586079 DOI: 10.1073/Pnas.1120045109  0.421
2012 Bentley AA, Merkulov SM, Peng Y, Rozmarynowycz R, Qi X, Pusztai-Carey M, Merrick WC, Yee VC, McCrae KR, Komar AA. Chimeric glutathione S-transferases containing inserts of kininogen peptides: Potential novel protein therapeutics Journal of Biological Chemistry. 287: 22142-22150. PMID 22577144 DOI: 10.1074/Jbc.M112.372854  0.307
2012 Komar AA, Mazumder B, Merrick WC. A new framework for understanding IRES-mediated translation Gene. 502: 75-86. PMID 22555019 DOI: 10.1016/J.Gene.2012.04.039  0.486
2011 Reineke LC, Cao Y, Baus D, Hossain NM, Merrick WC. Insights into the role of yeast eiF2A in Ires-Mediated translation Plos One. 6. PMID 21915340 DOI: 10.1371/Journal.Pone.0024492  0.73
2011 Krokowski D, Gaccioli F, Majumder M, Mullins MR, Yuan CL, Papadopoulou B, Merrick WC, Komar AA, Taylor D, Hatzoglou M. Characterization of hibernating ribosomes in mammalian cells. Cell Cycle (Georgetown, Tex.). 10: 2691-702. PMID 21768774 DOI: 10.4161/Cc.10.16.16844  0.421
2011 Parsyan A, Svitkin Y, Shahbazian D, Gkogkas C, Lasko P, Merrick WC, Sonenberg N. mRNA helicases: the tacticians of translational control. Nature Reviews. Molecular Cell Biology. 12: 235-45. PMID 21427765 DOI: 10.1038/Nrm3083  0.505
2011 Hussey GS, Chaudhury A, Dawson AE, Lindner DJ, Knudsen CR, Wilce MC, Merrick WC, Howe PH. Identification of an mRNP complex regulating tumorigenesis at the translational elongation step. Molecular Cell. 41: 419-31. PMID 21329880 DOI: 10.1016/J.Molcel.2011.02.003  0.36
2010 Lindqvist L, Robert F, Merrick W, Kakeya H, Fraser C, Osada H, Pelletier J. Inhibition of translation by cytotrienin A - A member of the ansamycin family Rna. 16: 2404-2413. PMID 20943818 DOI: 10.1261/Rna.2307710  0.396
2010 Dmitriev SE, Terenin IM, Andreev DE, Ivanov PA, Dunaevsky JE, Merrick WC, Shatsky IN. GTP-independent tRNA delivery to the ribosomal P-site by a novel eukaryotic translation factor Journal of Biological Chemistry. 285: 26779-26787. PMID 20566627 DOI: 10.1074/Jbc.M110.119693  0.473
2010 Merrick WC. Introduction to the thematic minireview series on protein synthesis Journal of Biological Chemistry. 285: 21195-21196. PMID 20444699 DOI: 10.1074/Jbc.R110.140012  0.448
2010 Merrick WC. Eukaryotic protein synthesis: Still a mystery Journal of Biological Chemistry. 285: 21197-21201. PMID 20444697 DOI: 10.1074/Jbc.R110.111476  0.546
2010 Schneider-Poetsch T, Ju J, Eyler DE, Dang Y, Bhat S, Merrick WC, Green R, Shen B, Liu JO. Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin. Nature Chemical Biology. 6: 209-217. PMID 20118940 DOI: 10.1038/Nchembio.304  0.432
2009 Reineke LC, Merrick WC. Characterization of the functional role of nucleotides within the URE2 IRES element and the requirements for eIF2A-mediated repression Rna. 15: 2264-2277. PMID 19861427 DOI: 10.1261/Rna.1722809  0.726
2009 Andreev DE, Dmitriev SE, Terenin IM, Prassolov VS, Merrick WC, Shatsky IN. Differential contribution of the m7G-cap to the 5′ end-dependent translation initiation of mammalian mRNAs Nucleic Acids Research. 37: 6135-6147. PMID 19696074 DOI: 10.1093/Nar/Gkp665  0.447
2009 Merrick W. Translation: Till termination us do part Nature. 459: 44-45. PMID 19424145 DOI: 10.1038/459044A  0.513
2009 Kaye NM, Emmett KJ, Merrick WC, Jankowsky E. Intrinsic RNA binding by the eukaryotic initiation factor 4F depends on a minimal RNA length but not on the m7G cap Journal of Biological Chemistry. 284: 17742-17750. PMID 19414591 DOI: 10.1074/Jbc.M109.009001  0.421
2009 Svitkin YV, Evdokimova VM, Brasey A, Pestova TV, Fantus D, Yanagiya A, Imataka H, Skabkin MA, Ovchinnikov LP, Merrick WC, Sonenberg N. General RNA-binding proteins have a function in poly(A)-binding protein-dependent translation. The Embo Journal. 28: 58-68. PMID 19078965 DOI: 10.1038/Emboj.2008.259  0.471
2008 Reineke LC, Komar AA, Caprara MG, Merrick WC. A small stem loop element directs internal initiation of the URE2 internal ribosome entry site in Saccharomyces cerevisiae Journal of Biological Chemistry. 283: 19011-19025. PMID 18460470 DOI: 10.1074/Jbc.M803109200  0.773
2008 Zeenko VV, Wang C, Majumder M, Komar AA, Snider MD, Merrick WC, Kaufman RJ, Hatzoglou M. An efficient in vitro translation system from mammalian cells lacking the translational inhibition caused by eIF2 phosphorylation Rna. 14: 593-602. PMID 18230759 DOI: 10.1261/Rna.825008  0.438
2007 Merrick WC, Barth-Baus D. Use of Reticulocyte Lysates for Mechanistic Studies of Eukaryotic Translation Initiation Methods in Enzymology. 429: 1-21. PMID 17913616 DOI: 10.1016/S0076-6879(07)29001-9  0.441
2007 Galkin O, Bentley AA, Gupta S, Compton BA, Mazumder B, Kinzy TG, Merrick WC, Hatzoglou M, Pestova TV, Hellen CUT, Komar AA. Roles of the negatively charged N-terminal extension of Saccharomyces cerevisiae ribosomal protein S5 revealed by characterization of a yeast strain containing human ribosomal protein S5 Rna. 13: 2116-2128. PMID 17901157 DOI: 10.1261/Rna.688207  0.399
2007 Mathonnet G, Fabian MR, Svitkin YV, Parsyan A, Huck L, Murata T, Biffo S, Merrick WC, Darzynkiewicz E, Pillai RS, Filipowicz W, Duchaine TF, Sonenberg N. MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F. Science (New York, N.Y.). 317: 1764-7. PMID 17656684 DOI: 10.1126/Science.1146067  0.361
2007 Dmitriev SE, Andreev DE, Terenin IM, Olovnikov IA, Prassolov VS, Merrick WC, Shatsky IN. Efficient translation initiation directed by the 900-nucleotide-long and GC-rich 5′ untranslated region of the human retrotransposon LINE-1 mRNA is strictly cap dependent rather than internal ribosome entry site mediated Molecular and Cellular Biology. 27: 4685-4697. PMID 17470553 DOI: 10.1128/Mcb.02138-06  0.415
2007 Kapasi P, Chaudhuri S, Vyas K, Baus D, Komar AA, Fox PL, Merrick WC, Mazumder B. L13a Blocks 48S Assembly: Role of a General Initiation Factor in mRNA-Specific Translational Control Molecular Cell. 25: 113-126. PMID 17218275 DOI: 10.1016/J.Molcel.2006.11.028  0.487
2007 Elroy-Stein O, Merrick WC. 6 Translation Initiation Via Cellular Internal Ribosome Entry Sites Cold Spring Harbor Monograph Archive. 48: 155-172. DOI: 10.1101/087969767.48.155  0.448
2006 Terenzi F, Hui DJ, Merrick WC, Sen GC. Distinct induction patterns and functions of two closely related interferon-inducible human genes, ISG54 and ISG56 Journal of Biological Chemistry. 281: 34064-34071. PMID 16973618 DOI: 10.1074/Jbc.M605771200  0.398
2006 Robert F, Kapp LD, Khan SN, Acker MG, Kolitz S, Kazemi S, Kaufman RJ, Merrick WC, Koromilas AE, Lorsch JR, Pelletier J. Initiation of protein synthesis by hepatitis C virus is refractory to reduced eIF2.GTP.Met-tRNA(i)(Met) ternary complex availability. Molecular Biology of the Cell. 17: 4632-44. PMID 16928960 DOI: 10.1091/Mbc.E06-06-0478  0.374
2006 Robert F, Gao HQ, Donia M, Merrick WC, Hamann MT, Pelletier J. Chlorolissoclimides: new inhibitors of eukaryotic protein synthesis. Rna (New York, N.Y.). 12: 717-25. PMID 16540697 DOI: 10.1261/Rna.2346806  0.384
2006 Pisarev AV, Kolupaeva VG, Pisareva VP, Merrick WC, Hellen CUT, Pestova TV. Specific functional interactions of nucleotides at key-3 and+4 positions flanking the initiation codon with components of the mammalian 48S translation initiation complex Genes and Development. 20: 624-636. PMID 16510876 DOI: 10.1101/Gad.1397906  0.352
2005 Low WK, Dang Y, Schneider-Poetsch T, Shi Z, Choi NS, Merrick WC, Romo D, Liu JO. Inhibition of eukaryotic translation initiation by the marine natural product pateamine A. Molecular Cell. 20: 709-22. PMID 16337595 DOI: 10.1016/J.Molcel.2005.10.008  0.474
2005 Honda K, Smith MA, Zhu X, Baus D, Merrick WC, Tartakoff AM, Hattier T, Harris PL, Siedlak SL, Fujioka H, Liu Q, Moreira PI, Miller FP, Nunomura A, Shimohama S, et al. Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. The Journal of Biological Chemistry. 280: 20978-86. PMID 15767256 DOI: 10.1074/Jbc.M500526200  0.311
2005 Komar AA, Gross SR, Barth-Baus D, Strachan R, Hensold JO, Goss Kinzy T, Merrick WC. Novel characteristics of the biological properties of the yeast Saccharomyces cerevisiae eukaryotic initiation factor 2A. The Journal of Biological Chemistry. 280: 15601-11. PMID 15718232 DOI: 10.1074/Jbc.M413728200  0.346
2005 Fernandez J, Yaman I, Huang C, Liu H, Lopez AB, Komar AA, Caprara MG, Merrick WC, Snider MD, Kaufman RJ, Lamers WH, Hatzoglou M. Ribosome stalling regulates ires-mediated translation in eukaryotes, a parallel to prokaryotic attenuation Molecular Cell. 17: 405-416. PMID 15694341 DOI: 10.1016/J.Molcel.2004.12.024  0.462
2005 Hui DJ, Terenzi F, Merrick WC, Sen GC. Mouse p56 blocks a distinct function of eukaryotic initiation factor 3 in translation initiation Journal of Biological Chemistry. 280: 3433-3440. PMID 15561726 DOI: 10.1074/Jbc.M406700200  0.47
2004 Orton KC, Ling J, Waskiewicz AJ, Cooper JA, Merrick WC, Korneeva NL, Rhoads RE, Sonenberg N, Traugh JA. Phosphorylation of Mnk1 by caspase-activated Pak2/gamma-PAK inhibits phosphorylation and interaction of eIF4G with Mnk. The Journal of Biological Chemistry. 279: 38649-57. PMID 15234964 DOI: 10.1074/Jbc.M407337200  0.309
2004 Merrick WC. Cap-dependent and cap-independent translation in eukaryotic systems Gene. 332: 1-11. PMID 15145049 DOI: 10.1016/J.Gene.2004.02.051  0.449
2004 Chan J, Khan SN, Harvey I, Merrick W, Pelletier J. Eukaryotic protein synthesis inhibitors identified by comparison of cytotoxicity profiles. Rna (New York, N.Y.). 10: 528-43. PMID 14970397 DOI: 10.1261/Rna.5200204  0.334
2003 Dmitriev SE, Terenin IM, Dunaevsky YE, Merrick WC, Shatsky IN. Assembly of 48S Translation Initiation Complexes from Purified Components with mRNAs that Have Some Base Pairing within Their 5′ Untranslated Regions Molecular and Cellular Biology. 23: 8925-8933. PMID 14645505 DOI: 10.1128/Mcb.23.24.8925-8933.2003  0.498
2003 Hui DJ, Bhasker CR, Merrick WC, Sen GC. Viral stress-inducible protein p56 inhibits translation by blocking the interaction of eIF3 with the ternary complex eIF2·GTP· Met-tRNAi Journal of Biological Chemistry. 278: 39477-39482. PMID 12885778 DOI: 10.1074/Jbc.M305038200  0.428
2003 Komar AA, Lesnik T, Cullin C, Merrick WC, Trachsel H, Altmann M. Internal initiation drives the synthesis of Ure2 protein lacking the prion domain and affects [URE3] propagation in yeast cells Embo Journal. 22: 1199-1209. PMID 12606584 DOI: 10.1093/Emboj/Cdg103  0.393
2003 Yang HS, Jansen AP, Komar AA, Zheng X, Merrick WC, Costes S, Lockett SJ, Sonenberg N, Colburn NH. The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation. Molecular and Cellular Biology. 23: 26-37. PMID 12482958 DOI: 10.1128/Mcb.23.1.26-37.2003  0.453
2003 Merrick WC. Initiation of Protein Biosynthesis in Eukaryotes Biochemistry and Molecular Biology Education. 31: 378-385. DOI: 10.1002/Bmb.2003.494031060274  0.524
2002 Rogers GW, Komar AA, Merrick WC. eIF4A: The godfather of the DEAD box helicases Progress in Nucleic Acid Research and Molecular Biology. 72: 307-331. PMID 12206455 DOI: 10.1016/S0079-6603(02)72073-4  0.456
2002 Zoll WL, Horton LE, Komar AA, Hensold JO, Merrick WC. Characterization of mammalian eIF2A and identification of the yeast homolog Journal of Biological Chemistry. 277: 37079-37087. PMID 12133843 DOI: 10.1074/Jbc.M207109200  0.426
2002 Pisarev AV, Skabkin MA, Thomas AA, Merrick WC, Ovchinnikov LP, Shatsky IN. Positive and negative effects of the major mammalian messenger ribonucleoprotein p50 on binding of 40 S ribosomal subunits to the initiation codon of β-globin mRNA Journal of Biological Chemistry. 277: 15445-15451. PMID 11854282 DOI: 10.1074/Jbc.M111954200  0.431
2002 Fernandez J, Yaman I, Merrick WC, Koromilas A, Wek RC, Sood R, Hensold J, Hatzoglou M. Regulation of internal ribosome entry site-mediated translation by eukaryotic initiation factor-2α phosphorylation and translation of a small upstream open reading frame Journal of Biological Chemistry. 277: 2050-2058. PMID 11684693 DOI: 10.1074/Jbc.M109199200  0.448
2002 Merrick W. Eukaryotic Translation Initiation Reactome - a Curated Knowledgebase of Biological Pathways. 1. DOI: 10.3180/React_2159.1  0.44
2001 Merrick WC, Hensold JO. Analysis of eukaryotic translation in purified and semipurified systems. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 11.9. PMID 18228314 DOI: 10.1002/0471143030.Cb1109S08  0.482
2001 Chen R, Knez JJ, Merrick WC, Edward Medof M. Comparative efficiencies of C-terminal signals of native glycophosphatidylinositol (GPI)-anchored proproteins in conferring GPI-anchoring Journal of Cellular Biochemistry. 84: 68-83. PMID 11746517 DOI: 10.1002/Jcb.1267  0.362
2001 Johnson CM, Perez DR, French R, Merrick WC, Donis RO. The NS5A protein of bovine viral diarrhoea virus interacts with the α subunit of translation elongation factor-1 Journal of General Virology. 82: 2935-2943. PMID 11714969 DOI: 10.1099/0022-1317-82-12-2935  0.394
2001 Browning KS, Gallie DR, Hershey JW, Hinnebusch AG, Maitra U, Merrick WC, Norbury C. Unified nomenclature for the subunits of eukaryotic initiation factor 3. Trends in Biochemical Sciences. 26: 284. PMID 11426420 DOI: 10.1016/S0968-0004(01)01825-4  0.579
2001 Rogers GW, Richter NJ, Lima WF, Merrick WC. Modulation of the Helicase Activity of eIF4A by eIF4B, eIF4H, and eIF4F Journal of Biological Chemistry. 276: 30914-30922. PMID 11418588 DOI: 10.1074/Jbc.M100157200  0.454
2001 Rogers GW, Lima WF, Merrick WC. Further characterization of the helicase activity of eIF4A. Substrate specificity Journal of Biological Chemistry. 276: 12598-12608. PMID 11278350 DOI: 10.1074/Jbc.M007560200  0.417
2001 Fernandez J, Yaman I, Mishra R, Merrick WC, Snider MD, Lamers WH, Hatzoglou M. Internal Ribosome Entry Site-mediated Translation of a Mammalian mRNA Is Regulated by Amino Acid Availability Journal of Biological Chemistry. 276: 12285-12291. PMID 11114306 DOI: 10.1074/Jbc.M009714200  0.453
2000 Guo J, Hui DJ, Merrick WC, Sen GC. A new pathway of translational regulation mediated by eukaryotic initiation factor 3 Embo Journal. 19: 6891-6899. PMID 11118224 DOI: 10.1093/Emboj/19.24.6891  0.425
2000 Merrick WC, Nyborg J. 3 The Protein Biosynthesis, Elongation Cycle Cold Spring Harbor Monograph Archive. 39: 89-125. DOI: 10.1101/087969618.39.89  0.351
2000 Hershey JWB, Merrick WC. 2 The Pathway and Mechanism of Initiation of Protein Synthesis Cold Spring Harbor Monograph Archive. 39: 33-88. DOI: 10.1101/087969618.39.33  0.513
1999 Richter NJ, Rogers GW, Hensold JO, Merrick WC. Further biochemical and kinetic characterization of human eukaryotic initiation factor 4H Journal of Biological Chemistry. 274: 35415-35424. PMID 10585411 DOI: 10.1074/Jbc.274.50.35415  0.468
1999 Li Q, Imataka H, Morino S, Rogers GW, Richter-Cook NJ, Merrick WC, Sonenberg N. Eukaryotic translation initiation factor 4AIII (eIF4AIII) is functionally distinct from eIF4AI and eIF4AII Molecular and Cellular Biology. 19: 7336-7346. PMID 10523622 DOI: 10.1128/Mcb.19.11.7336  0.494
1999 Rogers GW, Richter NJ, Merrick WC. Biochemical and kinetic characterization of the RNA helicase activity of eukaryotic initiation factor 4A Journal of Biological Chemistry. 274: 12236-12244. PMID 10212190 DOI: 10.1074/Jbc.274.18.12236  0.428
1998 Cavallius J, Merrick WC. Site-directed mutagenesis of yeast eEF1A: Viable mutants with altered nucleotide specificity Journal of Biological Chemistry. 273: 28752-28758. PMID 9786872 DOI: 10.1074/Jbc.273.44.28752  0.351
1998 Choi SK, Lee JH, Zoll WL, Merrick WC, Dever TE. Promotion of Met-tRNA(i)/(Met) binding to ribosomes by yIF2, a bacterial IF2 homolog in yeast Science. 280: 1757-1760. PMID 9624054 DOI: 10.1126/Science.280.5370.1757  0.706
1998 Kristensen P, Lund A, Clark BFC, Cavallius J, Merrick WC. Purification and characterisation of a tissue specific elongation factor 1 alpha (EF-1α2) from rabbit muscle Biochemical and Biophysical Research Communications. 245: 810-814. PMID 9588196 DOI: 10.1006/Bbrc.1998.8510  0.316
1998 Kahns S, Lund A, Kristensen P, Knudsen CR, Clark BFC, Cavallius J, Merrick WC. The elongation factor 1 A-2 isoform from rabbit: Cloning of the cDNA and characterization of the protein Nucleic Acids Research. 26: 1884-1890. PMID 9518480 DOI: 10.1093/Nar/26.8.1884  0.413
1998 Richter-Cook NJ, Dever TE, Hensold JO, Merrick WC. Purification and characterization of a new eukaryotic protein translation factor: Eukaryotic initiation factor 4h Journal of Biological Chemistry. 273: 7579-7587. PMID 9516461 DOI: 10.1074/Jbc.273.13.7579  0.709
1997 Asano K, Vornlocher HP, Richter-Cook NJ, Merrick WC, Hinnebusch AG, Hershey JW. Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly. The Journal of Biological Chemistry. 272: 27042-52. PMID 9341143 DOI: 10.1074/Jbc.272.43.27042  0.603
1997 Asano K, Merrick WC, Hershey JW. The translation initiation factor eIF3-p48 subunit is encoded by int-6, a site of frequent integration by the mouse mammary tumor virus genome. The Journal of Biological Chemistry. 272: 23477-80. PMID 9295280 DOI: 10.1074/Jbc.272.38.23477  0.447
1997 Merrick WC, Sonenberg N. Assays for eukaryotic translation factors that bind mRNA Methods: a Companion to Methods in Enzymology. 11: 333-342. PMID 9126548 DOI: 10.1006/Meth.1996.0431  0.475
1997 Cavallius J, Popkie AP, Merrick WC. Site-directed mutants of post-translationally modified sites of yeast eEF1A using a shuttle vector containing a chromogenic switch Biochimica Et Biophysica Acta - Gene Structure and Expression. 1350: 345-358. PMID 9061031 DOI: 10.1016/S0167-4781(96)00181-9  0.347
1997 Johnson KR, Merrick WC, Zoll WL, Zhu Y. Identification of cDNA clones for the large subunit of eukaryotic translation initiation factor 3. Comparison of homologues from human, Nicotiana tabacum, Caenorhabditis elegans, and Saccharomyces cerevisiae Journal of Biological Chemistry. 272: 7106-7113. PMID 9054404 DOI: 10.1074/Jbc.272.11.7106  0.427
1997 Asano K, Kinzy TG, Merrick WC, Hershey JW. Conservation and diversity of eukaryotic translation initiation factor eIF3. The Journal of Biological Chemistry. 272: 1101-9. PMID 8995409 DOI: 10.1074/Jbc.272.2.1101  0.427
1997 Block KL, Vornlocher HP, Asano K, Merrick WC, Hershey JWB. Cloning and characterization of mammalian cdnas encoding subunits of initiation factor eIF3 Faseb Journal. 11: A1401.  0.34
1997 Richter-Cook NJ, Dever TE, Merrick WC. Purification and characterization of a new eukaryotic translation factor: Eukaryotic translation factor 4h Faseb Journal. 11: A1402.  0.591
1996 Clark BFC, Grunberg-Manago M, Gupta NK, Hershey JWB, Hinnebusch AG, Jackson RJ, Maitra U, Mathews MB, Merrick WC, Rhoads RE, Sonenberg N, Spremulli LL, Trachsel H, Voorma HO. Prokaryotic and eukaryotic translation factors Biochimie. 78: 1119-1122. PMID 9150893 DOI: 10.1016/S0300-9084(97)86738-7  0.598
1996 Hershey JW, Asano K, Naranda T, Vornlocher HP, Hanachi P, Merrick WC. Conservation and diversity in the structure of translation initiation factor EIF3 from humans and yeast. Biochimie. 78: 903-7. PMID 9150866 DOI: 10.1016/S0300-9084(97)86711-9  0.468
1996 Merrick WC, Hershey JWB. 2 The Pathway and Mechanism of Eukaryotic Protein Synthesis Cold Spring Harbor Monograph Archive. 30: 31-69. DOI: 10.1101/087969458.30.31  0.5
1994 Pause A, Méthot N, Svitkin Y, Merrick WC, Sonenberg N. Dominant negative mutants of mammalian translation initiation factor eIF-4A define a critical role for eIF-4F in cap-dependent and cap-independent initiation of translation. The Embo Journal. 13: 1205-15. PMID 8131750 DOI: 10.1002/J.1460-2075.1994.Tb06370.X  0.38
1994 Gaspar NJ, Kinzy TG, Scherer BJ, Hümbelin M, Hershey JW, Merrick WC. Translation initiation factor eIF-2. Cloning and expression of the human cDNA encoding the gamma-subunit. The Journal of Biological Chemistry. 269: 3415-22. PMID 8106381  0.377
1994 Dever TE, Wei CL, Benkowski LA, Browning K, Merrick WC, Hershey JW. Determination of the amino acid sequence of rabbit, human, and wheat germ protein synthesis factor eIF-4C by cloning and chemical sequencing. The Journal of Biological Chemistry. 269: 3212-8. PMID 8106356  0.61
1994 Gonen H, Smith CE, Siegel NR, Kahana C, Merrick WC, Chakraburtty K, Schwartz AL, Ciechanover A. Protein synthesis elongation factor EF-1α is essential for ubiquitin-dependent degradation of certain Nα-acetylated proteins and may be substituted for by the bacterial elongation factor EF-Tu Proceedings of the National Academy of Sciences of the United States of America. 91: 7648-7652. PMID 8052636 DOI: 10.1073/Pnas.91.16.7648  0.336
1994 Merrick WC. Eukaryotic protein synthesis: An in vitro analysis Biochimie. 76: 822-830. PMID 7880898 DOI: 10.1016/0300-9084(94)90183-X  0.536
1993 Wu S, Gupta S, Chatterjee N, Hileman RE, Kinzy TG, Denslow ND, Merrick WC, Chakrabarti D, Osterman JC, Gupta NK. Cloning and characterization of complementary DNA encoding the eukaryotic initiation factor 2-associated 67-kDa protein (p67) Journal of Biological Chemistry. 268: 10796-10801. PMID 8496145  0.36
1993 Cavallius J, Zoll W, Chakraburtty K, Merrick WC. Characterization of yeast EF-1α: Non-conservation of post-translational modifications Biochimica Et Biophysica Acta (Bba)/Protein Structure and Molecular. 1163: 75-80. PMID 8476932 DOI: 10.1016/0167-4838(93)90281-U  0.309
1993 Hughes DL, Dever TE, Merrick WC. Further Biochemical Characterization of Rabbit Reticulocyte eIF-4B Archives of Biochemistry and Biophysics. 301: 311-319. PMID 8460942 DOI: 10.1006/Abbi.1993.1149  0.65
1993 Timmer RT, Lax SR, Hughes DL, Merrick WC, Ravel JM, Browning KS. Characterization of wheat germ protein synthesis initiation factor eIF-4C and comparison of eIF-4C from wheat germ and rabbit reticulocytes. The Journal of Biological Chemistry. 268: 24863-7. PMID 8227048  0.305
1993 Ray MK, Chakraborty A, Datta B, Chattopadhyay A, Saha D, Bose A, Kinzy TG, Wu S, Hileman RE, Merrick WC, Gupta NK. Characteristics of the eukaryotic initiation factor 2 associated 67-kDa polypeptide Biochemistry. 32: 5151-5159. PMID 8098621 DOI: 10.1021/Bi00070A026  0.365
1992 Anthony DD, Merrick WC. Analysis of 40 S and 80 S complexes with mRNA as measured by sucrose density gradients and primer extension inhibition Journal of Biological Chemistry. 267: 1554-1562. PMID 1730701  0.358
1992 Merrick WC. Mechanism and regulation of eukaryotic protein synthesis Microbiological Reviews. 56: 291-315. PMID 1620067  0.335
1992 Cavallius J, Merrick WC. Nucleotide sequence of rabbit elongation factor 1α cDNA Nucleic Acids Research. 20: 1422. PMID 1561101 DOI: 10.1093/Nar/20.6.1422  0.333
1992 Wolff EC, Kinzy TG, Merrick WC, Park MH. Two isoforms of eIF-5A in chick embryo: Isolation, activity, and comparison of sequences of the hypusine-containing proteins Journal of Biological Chemistry. 267: 6107-6113. PMID 1556119  0.323
1991 Bablanian R, Goswami SK, Esteban M, Banerjee AK, Merrick WC. Mechanism of selective translation of vaccinia virus mRNAs: Differential role of poly(A) and initiation factors in the translation of viral and cellular mRNAs Journal of Virology. 65: 4449-4460. PMID 2072458  0.352
1991 Anthony DD, Merrick WC. Eukaryotic initiation factor (eIF)-4F: Implications for a role in internal initiation of translation Journal of Biological Chemistry. 266: 10218-10226. PMID 2037575  0.415
1991 Tahara SM, Dietlin TA, Dever TE, Merrick WC, Worrilow LM. Effect of eukaryotic initiation factor 4F on AUG selection in a bicistronic mRNA Journal of Biological Chemistry. 266: 3594-3601. PMID 1995620  0.665
1991 Hammond ML, Merrick W, Bowman LH. Sequences mediating the translation of mouse S16 ribosomal protein mRNA during myoblast differentiation and in vitro and possible control points for the in vitro translation. Genes & Development. 5: 1723-36. PMID 1885008 DOI: 10.1101/gad.5.9.1723  0.371
1991 Jaramillo M, Dever TE, Merrick WC, Sonenberg N. RNA Unwinding in Translation: Assembly of Helicase Complex Intermediates Comprising Eukaryotic Initiation Factors eIF-4F and eIF-4B Molecular and Cellular Biology. 11: 5992-5997. PMID 1719376 DOI: 10.1128/Mcb.11.12.5992  0.639
1990 Anthony DD, Kinzy TG, Merrick WC. Affinity labeling of eukaryotic initiation factor 2 and elongation factor 1 alpha beta gamma with GTP analogs. Archives of Biochemistry and Biophysics. 281: 157-62. PMID 2383020 DOI: 10.1016/0003-9861(90)90426-Y  0.401
1990 Goss DJ, Carberry SE, Dever TE, Merrick WC, Rhoads RE. Fluorescence study of the binding of m7GpppG and rabbit globin mRNA to protein synthesis initiation factors 4A, 4E, and 4F. Biochemistry. 29: 5008-12. PMID 2378863 DOI: 10.1021/bi00473a002  0.631
1990 Tuazon PT, Morley SJ, Dever TE, Merrick WC, Rhoads RE, Traugh JA. Association of initiation factor eIF-4E in a cap binding protein complex (eIF-4F) is critical for and enhances phosphorylation by protein kinase C. The Journal of Biological Chemistry. 265: 10617-21. PMID 2355012  0.602
1990 Rozen F, Edery I, Meerovitch K, Dever TE, Merrick WC, Sonenberg N. Bidirectional RNA helicase activity of eucaryotic translation initiation factors 4A and 4F Molecular and Cellular Biology. 10: 1134-1144. PMID 2304461 DOI: 10.1128/Mcb.10.3.1134  0.668
1990 Riis B, Rattan SI, Clark BF, Merrick WC. Eukaryotic protein elongation factors. Trends in Biochemical Sciences. 15: 420-4. PMID 2278101 DOI: 10.1016/0968-0004(90)90279-K  0.461
1990 Conroy SC, Dever TE, Owens CL, Merrick WC. Characterization of the 46,000-Dalton subunit of eIF-4F Archives of Biochemistry and Biophysics. 282: 363-371. PMID 2241157 DOI: 10.1016/0003-9861(90)90130-Q  0.67
1990 Merrick WC, Dever TE, Kinzy TG, Conroy SC, Cavallius J, Owens CL. Characterization of protein synthesis factors from rabbit reticulocytes Bba - Gene Structure and Expression. 1050: 235-240. PMID 2207148 DOI: 10.1016/0167-4781(90)90173-Y  0.639
1990 Goss DJ, Carberry SE, Dever TE, Merrick WC, Rhoads RE. A fluorescence study of the interaction of protein synthesis initiation factors 4A, 4E, and 4F with mRNA and oligonucleotide analogs Bba - Gene Structure and Expression. 1050: 163-166. PMID 2207140 DOI: 10.1016/0167-4781(90)90160-4  0.687
1990 Jaramillo M, Browning K, Dever TE, Blum S, Trachsel H, Merrick WC, Ravel JM, Sonenberg N. Translation initiation factors that function as RNA helicases from mammals, plants and yeast. Biochimica Et Biophysica Acta. 1050: 134-9. PMID 2169888 DOI: 10.1016/0167-4781(90)90154-T  0.634
1990 Merrick WC. Overview: mechanism of translation initiation in eukaryotes. Enzyme. 44: 7-16. PMID 2133660  0.42
1990 Smith MR, Jaramillo M, Ya-lun L, Dever TE, Merrick WC, Kung Hsiang-fu K, Sonenberg N. Translation initiation factors induce DNA synthesis and transform NIH 3T3 cells New Biologist. 2: 648-654. PMID 2083255  0.661
1989 Rosenberry TL, Krall JA, Dever TE, Haas R, Louvard D, Merrick WC. Biosynthetic incorporation of [3H]ethanolamine into protein synthesis elongation factor 1α reveals a new post-translational protein modification Journal of Biological Chemistry. 264: 7096-7099. PMID 2708357  0.608
1989 Lawson TG, Lee KA, Maimone MM, Abramson RD, Dever TE, Merrick WC, Thach RE. Dissociation of double-stranded polynucleotide helical structures by eukaryotic initiation factors, as revealed by a novel assay Biochemistry. 28: 4729-4734. PMID 2548591  0.651
1989 Dever TE, Costello CE, Owens CL, Rosenberry TL, Merrick WC. Location of seven post-translational modifications in rabbit elongation factor 1α including dimethyllysine, trimethyllysine, and glycerylphosphorylethanolamine Journal of Biological Chemistry. 264: 20518-20525. PMID 2511205  0.566
1989 Smit-McBride Z, Dever TE, Hershey JW, Merrick WC. Sequence determination and cDNA cloning of eukaryotic initiation factor 4D, the hypusine-containing protein. The Journal of Biological Chemistry. 264: 1578-83. PMID 2492279  0.622
1988 Mick SJ, Abramson RD, Ray BK, Merrick WC, Thach RE, Hagedorn CH. Induction of eIF-4E phosphorylation by the addition of L-pyrroline-5-carboxylic acid to rabbit reticulocyte lysate. Febs Letters. 236: 484-8. PMID 3410057 DOI: 10.1016/0014-5793(88)80082-6  0.402
1988 Lawson TG, Cladaras MH, Ray BK, Lee KA, Abramson RD, Merrick WC, Thach RE. Discriminatory interaction of purified eukaryotic initiation factors 4F plus 4A with the 5' ends of reovirus messenger RNAs. The Journal of Biological Chemistry. 263: 7266-76. PMID 3366779  0.389
1988 Abramson RD, Browning KS, Dever TE, Lawson TG, Thach RE, Ravel JM, Merrick WC. Initiation factors that bind mRNA. A comparison of mammalian factors with wheat germ factors. The Journal of Biological Chemistry. 263: 5462-7. PMID 3356693  0.657
1988 Abramson RD, Dever TE, Merrick WC. Biochemical evidence supporting a mechanism for cap-independent and internal initiation of eukaryotic mRNA Journal of Biological Chemistry. 263: 6016-6019. PMID 2966150  0.622
1988 McMullin EL, Hogancamp WE, Abramson RD, Merrick WC, Hagedorn CH. Phosphorylation of the p220 subunit of eIF-4F by cAMP dependent protein kinase and protein kinase C in vitro. Biochemical and Biophysical Research Communications. 153: 925-32. PMID 2839173 DOI: 10.1016/S0006-291X(88)81316-0  0.363
1987 Dever TE, Glynias MJ, Merrick WC. GTP-binding domain: three consensus sequence elements with distinct spacing. Proceedings of the National Academy of Sciences of the United States of America. 84: 1814-8. PMID 3104905 DOI: 10.1073/Pnas.84.7.1814  0.622
1987 Abramson RD, Dever TE, Lawson TG, Ray BK, Thach RE, Merrick WC. The ATP-dependent interaction of eukaryotic initiation factors with mRNA. Journal of Biological Chemistry. 262: 3826-3832. PMID 2950099  0.659
1986 Lawson TG, Ray BK, Dodds JT, Grifo JA, Abramson RD, Merrick WC, Betsch DF, Weith HL, Thach RE. Influence of 5' proximal secondary structure on the translational efficiency of eukaryotic mRNAs and on their interaction with initiation factors. The Journal of Biological Chemistry. 261: 13979-89. PMID 3771516  0.403
1986 Ray BK, Lawson TG, Abramson RD, Merrick WC, Thach RE. Recycling of messenger RNA cap-binding proteins mediated by eukaryotic initiation factor 4B. The Journal of Biological Chemistry. 261: 11466-70. PMID 3745151  0.355
1985 Ray BK, Lawson TG, Kramer JC, Cladaras MH, Grifo JA, Abramson RD, Merrick WC, Thach RE. ATP-dependent unwinding of messenger RNA structure by eukaryotic initiation factors Journal of Biological Chemistry. 260: 7651-7658. PMID 3838990  0.357
1985 Reichel PA, Merrick WC, Siekierka J, Mathews MB. Regulation of a protein synthesis initiation factor by adenovirus virus-associated RNAI Nature. 313: 196-200. PMID 2578613 DOI: 10.1038/313196A0  0.357
1984 Carvalho MDGDC, Carvalho JF, Merrick WC. Biological characterization of various forms of elongation factor 1 from rabbit reticulocytes Archives of Biochemistry and Biophysics. 234: 603-611. PMID 6568109 DOI: 10.1016/0003-9861(84)90310-2  0.32
1984 Carvalho JF, Carvalho MDGDC, Merrick WC. Purification of various forms of elongation factor 1 from rabbit reticulocytes Archives of Biochemistry and Biophysics. 234: 591-602. PMID 6497388 DOI: 10.1016/0003-9861(84)90309-6  0.306
1984 Grifo JA, Abramson RD, Satler CA, Merrick WC. RNA-stimulated ATPase activity of eukaryotic initiation factors Journal of Biological Chemistry. 259: 8648-8654. PMID 6145716  0.369
1983 Schatzman RC, Grifo JA, Merrick WC, Kuo JF. Phospholipid-sensitive Ca2+-dependent protein kinase phosphorylates the beta subunit of eukaryotic initiation factor 2 (eIF-2). Febs Letters. 159: 167-70. PMID 6873292 DOI: 10.1016/0014-5793(83)80439-6  0.316
1983 Grifo JA, Tahara SM, Morgan MA, Shatkin AJ, Merrick WC. New initiation factor activity required for globin mRNA translation. The Journal of Biological Chemistry. 258: 5804-10. PMID 6853548  0.408
1983 Ray BK, Brendler TG, Adya S, Daniels-McQueen S, Miller JK, Hershey JW, Grifo JA, Merrick WC, Thach RE. Role of mRNA competition in regulating translation: further characterization of mRNA discriminatory initiation factors. Proceedings of the National Academy of Sciences of the United States of America. 80: 663-7. PMID 6572361 DOI: 10.1073/Pnas.80.3.663  0.529
1983 Merrick WC. Translation of exogenous mRNAs in reticulocyte lysates Methods in Enzymology. 606-615. PMID 6136894 DOI: 10.1016/0076-6879(83)01041-1  0.404
1982 Grifo JA, Tahara SM, Leis JP, Morgan MA, Shatkin AJ, Merrick WC. Characterization of eukaryotic initiation factor 4A, a protein involved in ATP-dependent binding of globin mRNA. The Journal of Biological Chemistry. 257: 5246-52. PMID 7068683  0.384
1982 Kuroda Y, Merrick WC, Sharma RK. Polyamines inhibit the protein kinase 380-catalyzed phosphorylation of eukaryotic initiation factor 2α Science. 215: 415-416. PMID 7058326 DOI: 10.1126/Science.7058326  0.385
1982 Kuroda Y, Merrick WC, Sharma RK. Specific phosphorylation of eukaryotic initiation factor 2α, elF-2α, by bovine adrenocortical cyclic nucleotide-independent protein kinase, PK 380 Archives of Biochemistry and Biophysics. 213: 271-275. PMID 6277252 DOI: 10.1016/0003-9861(82)90462-3  0.363
1979 Kemper WM, Merrick WC. [58] Preparation of protein synthesis elongation factors from rabbit reticulocytes Methods in Enzymology. 60: 638-648. PMID 459919 DOI: 10.1016/S0076-6879(79)60060-5  0.355
1979 Merrick WC. [9] Assays for eukaryotic protein synthesis Methods in Enzymology. 60: 108-123. PMID 459892 DOI: 10.1016/S0076-6879(79)60011-3  0.391
1979 Merrick WC. [8] Purification of protein synthesis initiation factors from rabbit reticulocytes Methods in Enzymology. 60: 101-108. PMID 459891 DOI: 10.1016/S0076-6879(79)60010-1  0.455
1979 Floyd GA, Merrick WC, Traugh JA. Identification of initiation factors and ribosome-associated phosphoproteins by two-dimensional polyacrylamide gel electrophoresis European Journal of Biochemistry. 96: 277-286. PMID 456373 DOI: 10.1111/J.1432-1033.1979.Tb13038.X  0.48
1978 Tahara SM, Traugh JA, Sharp SB, Lundak TS, Safer B, Merrick WC. Effect of hemin on site-specific phosphorylation of eukaryotic initiation factor 2 Proceedings of the National Academy of Sciences of the United States of America. 75: 789-793. PMID 273242 DOI: 10.1073/Pnas.75.2.789  0.375
1978 Sonenberg N, Morgan MA, Merrick WC, Shatkin AJ. A polypeptide in eukaryotic initiation factors that crosslinks specifically to the 5'-terminal cap in mRNA. Proceedings of the National Academy of Sciences of the United States of America. 75: 4843-7. PMID 217002  0.399
1977 Anderson WF, Bosch L, Cohn WE, Lodish H, Merrick WC, Weissbach H, Wittmann HG, Wool IG. International symposium on protein synthesis Summary of Fogarty Center-NIH Workshop held in Bethesda, Maryland on 18-20 October, 1976 Febs Letters. 76: 1-10. PMID 323054 DOI: 10.1016/0014-5793(77)80109-9  0.382
1976 Safer B, Adams SL, Kemper WM, Berry KW, Lloyd M, Merrick WC. Purification and characterization of two initiation factors required for maximal activity of a highly fractionated globin mRNA translation system Proceedings of the National Academy of Sciences of the United States of America. 73: 2584-2588. PMID 1066667 DOI: 10.1073/Pnas.73.8.2584  0.326
1976 Nombela C, Nombela NA, Ochoa S, Safer B, Anderson WF, Merrick WC. Polypeptide chain initiation in eukaryotes: mechanism of formation of initiation complex Proceedings of the National Academy of Sciences of the United States of America. 73: 298-301. PMID 1061132 DOI: 10.1073/Pnas.73.2.298  0.353
1976 Filipowicz W, Sierra JM, Nombela C, Ochoa S, Merrick WC, Anderson WF. Polypeptide chain initiation in eukaryotes: Initiation factor requirements for translation of natural messengers Proceedings of the National Academy of Sciences of the United States of America. 73: 44-48. PMID 1061126 DOI: 10.1073/pnas.73.1.44  0.348
1976 Kemper WM, Berry KW, Merrick WC. Purification and properties of rabbit reticulocyte protein synthesis initiation factors M2Bα and M2Bβ Journal of Biological Chemistry. 251: 5551-5557. PMID 965377  0.349
1976 Shafritz DA, Weinstein JA, Safer B, Merrick WC, Weber LA, Hickey ED, Baglioni C. Evidence for role of m7G5'-phosphate group in recognition of eukaryotic mRNA by initiation factor IF-M3. Nature. 261: 291-4. PMID 944862 DOI: 10.1038/261291A0  0.364
1976 Golini F, Thach SS, Birge CH, Safer B, Merrick WC, Thach RE. Competition between cellular and viral mRNAs in vitro is regulated by a messenger discriminatory initiation factor Proceedings of the National Academy of Sciences of the United States of America. 73: 3040-3044. PMID 184455 DOI: 10.1073/Pnas.73.9.3040  0.482
1976 Traugh JA, Tahara SM, Sharp SB, Safer B, Merrick WC. Factors involved in initiation of haemoglobin synthesis can be phosphorylated in vitro Nature. 263: 163-165. PMID 184395 DOI: 10.1038/263163A0  0.344
1975 Anderson WF, Barker JE, Elson NA, Merrick WC, Steggles AW, Wilson GN, Kantor JA, Nienhuis AW. Activation and inactivation of genes determining hemoglobin types Journal of Cellular Physiology. 85: 477-494. PMID 1168204 DOI: 10.1002/Jcp.1040850413  0.497
1975 Nombela C, Nombela NA, Ochoa S, Merrick WC, Anderson F. Nature of eukaryotic proteins required for joining of 40S and 60S ribosomal subunits. Biochemical and Biophysical Research Communications. 63: 409-16. PMID 1125031 DOI: 10.1016/0006-291X(75)90703-2  0.628
1975 Elson NA, Adams SL, Merrick WC, Safer B, Anderson WF. Comparison of fMet-tRNAf and Met-tRNAf from Escherichia coli and rabbit liver in initiation of hemoglobin synthesis Journal of Biological Chemistry. 250: 3074-3079. PMID 1091646  0.346
1975 Clemens MJ, Safer B, Merrick WC, Anderson WF, London IM. Inhibition of protein synthesis in rabbit reticulocyte lysates by double-stranded RNA and oxidized glutathione: indirect mode of action on polypeptide chain initiation. Proceedings of the National Academy of Sciences of the United States of America. 72: 1286-90. PMID 805425 DOI: 10.1073/pnas.72.4.1286  0.349
1974 Merrick WC, Graf H, Anderson WF. [13] Preparation of protein synthesis initiation factors IF-M1, IF-M2A, and IF-M2B from rabbit reticulocytes Methods in Enzymology. 30: 128-136. PMID 4853750 DOI: 10.1016/0076-6879(74)30015-8  0.322
1972 Crystal RG, Nienhuis AW, Prichard PM, Picciano D, Elson NA, Merrick WC, Graf H, Shafritz DA, Laycock DG, Last JA, Anderson WF. Initiation of globin synthesis Febs Letters. 24: 310-314. DOI: 10.1016/0014-5793(72)80379-X  0.417
Low-probability matches (unlikely to be authored by this person)
1987 Huang WI, Hansen LJ, Merrick WC, Jagus R. Inhibitor of eukaryotic initiation factor 4F activity in unfertilized sea urchin eggs. Proceedings of the National Academy of Sciences of the United States of America. 84: 6359-63. PMID 3476952  0.297
1981 Kluve B, Merrick WC, Stanbridge EJ, Gershman H. Mycoplasmas induce collagenase in BALB/c 3T3 cells Nature. 292: 855-857. PMID 6267475 DOI: 10.1038/292855A0  0.295
1983 Daniels-McQueen S, Detjen BM, Grifo JA, Merrick WC, Thach RE. Unusual requirements for optimum translation of polio viral RNA in vitro Journal of Biological Chemistry. 258: 7195-7199. PMID 6304083  0.291
2016 Merrick WC. The Celebration of 40 years of structural biology at Aarhus University as seen through the eyes of a translationalist. New Biotechnology. PMID 27664793 DOI: 10.1016/J.Nbt.2016.09.004  0.29
1995 Iversen L, Kristensen P, Nissen JB, Merrick WC, Kragballe K. Purification and characterization of leukotriene A4 hydrolase from human epidermis Febs Letters. 358: 316-322. PMID 7843421 DOI: 10.1016/0014-5793(94)01459-E  0.289
1975 Safer B, Adams SL, Anderson WF, Merrick WC. Binding of met tRNA and GTP to homogeneous initiation factor MP Journal of Biological Chemistry. 250: 9076-9082. PMID 1104615  0.286
1997 Wang JF, Engelsberg BN, Johnson SW, Witmer C, Merrick WC, Rozmiarek H, Billings PC. DNA binding activity of the mammalian translation elongation complex: Recognition of chromium- and transplatin damaged DNA Archives of Toxicology. 71: 450-454. PMID 9209691 DOI: 10.1007/S002040050410  0.286
1975 Adams SL, Safer B, Anderson WF, Merrick WC. Eukaryotic initiation complex formation. Evidence for two distinct pathways Journal of Biological Chemistry. 250: 9083-9089. PMID 1194278  0.283
1979 Peterson DT, Merrick WC, Safer B. Binding and release of radiolabeled eukaryotic initiation factors 2 and 3 during 80 S initiation complex formation Journal of Biological Chemistry. 254: 2509-2516. PMID 429297  0.281
1988 McMullin EL, Haas DW, Abramson RD, Thach RE, Merrick WC, Hagedorn CH. Identification of a protein kinase activity in rabbit reticulocytes that phosphorylates the mRNA cap binding protein. Biochemical and Biophysical Research Communications. 153: 340-6. PMID 2967701 DOI: 10.1016/S0006-291X(88)81228-2  0.28
1982 Hiatt WR, Garcia R, Merrick WC, Sypherd PS. Methylation of elongation factor lα from the fungus Mucor Proceedings of the National Academy of Sciences of the United States of America. 79: 3433-3437. PMID 6808511 DOI: 10.1073/pnas.79.11.3433  0.278
1971 Merrick WC, Dure LS. Specific transformylation of one methionyl-tRNA from cotton seeding chloroplasts by endogenous and Escherichia coli transformylases Proceedings of the National Academy of Sciences of the United States of America. 68: 641-644. PMID 5276774 DOI: 10.1073/Pnas.68.3.641  0.278
2022 Izidoro MS, Sokabe M, Villa N, Merrick WC, Fraser CS. Human eukaryotic initiation factor 4E (eIF4E) and the nucleotide-bound state of eIF4A regulate eIF4F binding to RNA. The Journal of Biological Chemistry. 102368. PMID 35963437 DOI: 10.1016/j.jbc.2022.102368  0.276
1973 Picciano DJ, Prichard PM, Merrick WC, Shafritz DA, Graf H, Crystal RG, Anderson WF. Isolation of protein synthesis initiation factors from rabbit liver Journal of Biological Chemistry. 248: 204-214. PMID 4692830  0.27
2021 Anderson R, Agarwal A, Ghosh A, Guan BJ, Casteel J, Dvorina N, Baldwin WM, Mazumder B, Nazarko TY, Merrick WC, Buchner DA, Hatzoglou M, Kondratov RV, Komar AA. eIF2A-knockout mice reveal decreased life span and metabolic syndrome. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21990. PMID 34665898 DOI: 10.1096/fj.202101105R  0.27
1991 Merrick WC. Everything you wanted to know about protein synthesis ... Almost New Biologist. 3: 660-666. PMID 1684286  0.267
1975 Merrick WC, Kemper WM, Anderson WF. Purification and characterization of homogeneous initiation factor M2A from rabbit reticulocytes Journal of Biological Chemistry. 250: 5556-5562. PMID 1095581  0.267
1975 Safer B, Anderson WF, Merrick WC. Purification and physical properties of homogeneous initiation factor MP from rabbit reticulocytes Journal of Biological Chemistry. 250: 9067-9075. PMID 1194277  0.266
1993 Yang W, Burkhart W, Cavallius J, Merrick WC, Boss WF. Purification and characterization of a phosphatidylinositol 4-kinase activator in carrot cells Journal of Biological Chemistry. 268: 392-398. PMID 8380160  0.265
1980 Lloyd MA, Osborne JC, Safer B, Powell GM, Merrick WC. Characteristics of eukaryotic initiation factor 2 and its subunits. The Journal of Biological Chemistry. 255: 1189-93. PMID 6153180  0.265
1973 Merrick WC, Lubsen NH, Anderson WF. A ribosome dissociation factor from rabbit reticulocytes distinct from initiation factor M3 Proceedings of the National Academy of Sciences of the United States of America. 70: 2220-2223. PMID 4525161  0.259
1979 Merrick WC. Evidence that a single GTP is used in the formation of 80 S initiation complexes Journal of Biological Chemistry. 254: 3708-3711. PMID 438155  0.256
1999 Carr-Schmid A, Durko N, Cavallius J, Merrick WC, Kinzy TG. Mutations in a GTP-binding motif of eukaryotic elongation factor 1A reduce both translational fidelity and the requirement for nucleotide exchange Journal of Biological Chemistry. 274: 30297-30302. PMID 10514524 DOI: 10.1074/Jbc.274.42.30297  0.247
1989 Tuazon PT, Merrick WC, Traugh JA. Comparative analysis of phosphorylation of translational initiation and elongation factors by seven protein kinases. The Journal of Biological Chemistry. 264: 2773-7. PMID 2914929  0.247
2010 Schneider-Poetsch T, Ju J, Eyler DE, Dang Y, Bhat S, Merrick WC, Green R, Shen B, Liu JO. Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin Nature Chemical Biology. 6: 209-217. DOI: 10.1038/nchembio.304  0.247
1993 Yoder-Hill J, Pause A, Sonenberg N, Merrick WC. The p46 subunit of eukaryotic initiation factor (eIF)-4F exchanges with eIF-4A. The Journal of Biological Chemistry. 268: 5566-73. PMID 8449919  0.242
2017 Guan BJ, van Hoef V, Jobava R, Elroy-Stein O, Valasek LS, Cargnello M, Gao XH, Krokowski D, Merrick WC, Kimball SR, Komar AA, Koromilas AE, Wynshaw-Boris A, Topisirovic I, Larsson O, et al. A Unique ISR Program Determines Cellular Responses to Chronic Stress. Molecular Cell. 68: 885-900.e6. PMID 29220654 DOI: 10.1016/j.molcel.2017.11.007  0.237
2017 Guan BJ, van Hoef V, Jobava R, Elroy-Stein O, Valasek LS, Cargnello M, Gao XH, Krokowski D, Merrick WC, Kimball SR, Komar AA, Koromilas AE, Wynshaw-Boris A, Topisirovic I, Larsson O, et al. A Unique ISR Program Determines Cellular Responses to Chronic Stress. Molecular Cell. 68: 885-900.e6. PMID 29220654 DOI: 10.1016/j.molcel.2017.11.007  0.237
1991 Kinzy TG, Merrick WC. Characterization of a limited trypsin digestion form of eukaryotic elongation factor 1α Journal of Biological Chemistry. 266: 4099-4105. PMID 1999404  0.233
2010 Merrick WC. Found in translation - the discovery of the first RNA helicase, eIF4A Rsc Biomolecular Sciences. v-x.  0.222
1979 Peterson DT, Safer B, Merrick WC. Role of eukaryotic initiation factor 5 in the formation of 80 S initiation complexes Journal of Biological Chemistry. 254: 7730-7735. PMID 468782  0.218
1992 Kinzy TG, Freeman JP, Johnson AE, Merrick WC. A model for the aminoacyl-tRNA binding site of eukaryotic elongation factor 1 alpha. The Journal of Biological Chemistry. 267: 1623-32. PMID 1730707  0.212
2001 Korneeva NL, Lamphear BJ, Hennigan FLC, Merrick WC, Rhoads RE. Characterization of the Two eIF4A-binding Sites on Human eIF4G-1 Journal of Biological Chemistry. 276: 2872-2879. PMID 11060291 DOI: 10.1074/jbc.M006345200  0.201
1975 Merrick WC, Kemper WM, Kantor JA, Anderson WF. Purification and properties of rabbit reticulocyte protein synthesis elongation factor 2 Journal of Biological Chemistry. 250: 2620-2625. PMID 1091638  0.2
1990 Merrick WC. Gene expression using cell-free systems. Current Opinion in Biotechnology. 1: 79-81. PMID 1367920 DOI: 10.1016/0958-1669(90)90014-C  0.196
1985 Mosenkis J, Daniels-McQueen S, Janovec S, Duncan R, Hershey JW, Grifo JA, Merrick WC, Thach RE. Shutoff of host translation by encephalomyocarditis virus infection does not involve cleavage of the eucaryotic initiation factor 4F polypeptide that accompanies poliovirus infection. Journal of Virology. 54: 643-5. PMID 2985829 DOI: 10.1128/Jvi.54.2.643-645.1985  0.193
1976 Twardowski T, Redfield B, Kemper WM, Merrick WC, Weissbach H. Studies on the disaggregation of elongation factor by elastase Biochemical and Biophysical Research Communications. 71: 272-279. PMID 962919 DOI: 10.1016/0006-291X(76)90267-9  0.192
1976 Twardowski T, Redfield B, Kemper WM, Merrick WC, Weissbach H. Studies on the disaggregation of Elongation factor 1 by elastase Biochemical and Biophysical Research Communications. 71: 274-279. DOI: 10.1016/0006-291X(76)90278-3  0.192
2021 Jobava R, Mao Y, Guan BJ, Hu D, Krokowski D, Chen CW, Shu XE, Chukwurah E, Wu J, Gao Z, Zagore LL, Merrick WC, Trifunovic A, Hsieh AC, Valadkhan S, et al. Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress. Molecular Cell. 81: 4191-4208.e8. PMID 34686314 DOI: 10.1016/j.molcel.2021.09.029  0.181
1976 Kemper WM, Merrick WC, Redfield B, Liu CK, Weissbach H. Purification and properties of rabbit reticulocyte elongation factor 1 Archives of Biochemistry and Biophysics. 174: 603-612. PMID 1230010 DOI: 10.1016/0003-9861(76)90366-0  0.18
1980 Tuazon PT, Merrick WC, Traugh JA. Site-specific phosphorylation if initiation factor 2 by three cyclic nucleotide-independent protein kinases. The Journal of Biological Chemistry. 255: 10954-8. PMID 7430164  0.177
1975 Merrick WC, Anderson WF. Purification and characterization of homogeneous protein synthesis initiation factor M1 from rabbit reticulocytes Journal of Biological Chemistry. 250: 1197-1206. PMID 1112800  0.173
1972 Shafritz DA, Prichard PM, Gilbert JM, Merrick WC, Anderson WF. Separation of reticulocyte initiation factor M 2 activity into two components Proceedings of the National Academy of Sciences of the United States of America. 69: 983-987. PMID 4502947  0.171
1976 Krueger LJ, Weiss GB, Merrick WC, Lloyd MA, Anderson WF. Cycling of RNA-directed DNA polymerase on natural and synthetic RNA templates Nature. 260: 363-365. PMID 56719 DOI: 10.1038/260363a0  0.162
1997 Cavallius J, Merrick WC. Site-directed mutagenesis of yeast eefia; viable mutants with altered nucleotide specificity Faseb Journal. 11: A1402.  0.131
2007 Merrick WC. Are we there yet? Nature Chemical Biology. 3: 19-20. PMID 17173023 DOI: 10.1038/nchembio0107-19  0.12
1985 Rayford R, Anthony DD, O'Neill RE, Merrick WC. Reductive alkylation with oxidized nucleotides. Use in affinity labeling or affinity chromatography Journal of Biological Chemistry. 260: 15708-15713. PMID 2999131  0.106
1983 Kluve B, Merrick WC, Gershman H. Mycoplasma-induced BALB/c 3T3 collagenase is a mammalian enzyme Biochemical Journal. 212: 641-647. PMID 6309150  0.104
1985 Rayford R, Anthony D, O'Neill R, Merrick WC. Reductive akylation with oxidized nucleotides: Use in affinity labelling or affinity chromatography Federation Proceedings. 44: No. 7069.  0.08
1972 Merrick WC, Dure LS. The developmental biochemistry of cotton seed embryogenesis and germination. IV. Levels of cytoplasmic and chloroplastic transfer ribonucleic acid species Journal of Biological Chemistry. 247: 7988-7999. PMID 4565670  0.067
1973 Merrick WC, Dure LS. Developmental biochemistry of cottonseed embryogenesis and germination. Preferential charging of cotton chloroplastic transfer ribonucleic acid by Escherichia coli enzymes Biochemistry. 12: 629-635. PMID 4570849  0.064
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