Daniel Mansuy - Publications

Affiliations: 
Universite Paris Descartes, Paris, Île-de-France, France 

269 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Dali MM, Dansette PM, Mansuy D, Boucher JL. Comparison of various aryl-dithiolethiones and aryl-dithiolones as hydrogen sulfide, H2S, donors in the presence of rat liver microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 32234734 DOI: 10.1124/Dmd.119.090274  1
2019 Dulac M, Nagarathinan C, Dansette PM, Mansuy D, Boucher JL. Mechanism of H2S formation from the metabolism of anetholedithiolethione and anetholedithiolone by rat liver microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 31213461 DOI: 10.1124/Dmd.119.087205  1
2018 Dulac M, Sassi A, Nagarathinan C, Christen MO, Dansette PM, Mansuy D, Boucher JL. Metabolism of anethole dithiolethione by rat and human liver microsomes: formation of various products deriving from its O-demethylation and S-oxidation. Involvement of cytochromes P450 and flavin monooxygenases in these pathways. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 30018103 DOI: 10.1124/Dmd.118.082545  1
2018 Lafite P, André F, Graves JP, Zeldin DC, Dansette PM, Mansuy D. Role of Arginine 117 in Substrate Recognition by Human Cytochrome P450 2J2. International Journal of Molecular Sciences. 19. PMID 30012976 DOI: 10.3390/Ijms19072066  1
2018 Wang Y, Dansette PM, Pigeon P, Top S, McGlinchey MJ, Mansuy D, Jaouen G. A new generation of ferrociphenols leads to a great diversity of reactive metabolites, and exhibits remarkable antiproliferative properties. Chemical Science. 9: 70-78. PMID 29629075 DOI: 10.1039/C7Sc04213B  1
2017 Durand CM, Dhers L, Tesson C, Tessa A, Fouillen L, Jacqueré S, Raymond L, Coupry I, Benard G, Darios F, El-Hachimi KH, Astrea G, Rivier F, Banneau G, Pujol C, ... ... Mansuy D, et al. CYP2U1 activity is altered by missense mutations in hereditary spastic paraplegia 56. Human Mutation. PMID 29034544 DOI: 10.1002/Humu.23359  0.44
2017 Ducassou L, Dhers L, Jonasson G, Pietrancosta N, Boucher JL, Mansuy D, André F. Membrane-bound human orphan cytochrome P450 2U1: Sequence singularities, construction of a full 3D model, and substrate docking. Biochimie. PMID 28743672 DOI: 10.1016/j.biochi.2017.07.007  0.44
2016 Dhers L, Pietrancosta N, Ducassou L, Ramassamy B, Dairou J, Jaouen M, André F, Mansuy D, Boucher JL. Spectral and 3D model studies of the interaction of orphan human cytochrome P450 2U1 with substrates and ligands. Biochimica Et Biophysica Acta. PMID 27456766 DOI: 10.1016/j.bbagen.2016.07.018  0.56
2016 Wang Y, Richard MA, Top S, Dansette PM, Pigeon P, Vessières A, Mansuy D, Jaouen G. Ferrocenyl Quinone Methide-Thiol Adducts as New Antiproliferative Agents: Synthesis, Metabolic Formation from Ferrociphenols, and Oxidative Transformation. Angewandte Chemie (International Ed. in English). PMID 27276169 DOI: 10.1002/Anie.201603931  1
2015 Dansette PM, Levent D, Hessani A, Mansuy D. Bioactivation of clopidogrel and prasugrel: factors determining the stereochemistry of the thiol metabolite double bond. Chemical Research in Toxicology. 28: 1338-45. PMID 25970225 DOI: 10.1021/Acs.Chemrestox.5B00133  1
2015 Richard MA, Hamels D, Pigeon P, Top S, Dansette PM, Lee HZ, Vessières A, Mansuy D, Jaouen G. Oxidative metabolism of ferrocene analogues of tamoxifen: characterization and antiproliferative activities of the metabolites. Chemmedchem. 10: 981-90. PMID 25882581 DOI: 10.1002/Cmdc.201500075  1
2015 Ducassou L, Jonasson G, Dhers L, Pietrancosta N, Ramassamy B, Xu-Li Y, Loriot MA, Beaune P, Bertho G, Lombard M, Mansuy D, André F, Boucher JL. Expression in yeast, new substrates, and construction of a first 3D model of human orphan cytochrome P450 2U1: Interpretation of substrate hydroxylation regioselectivity from docking studies. Biochimica Et Biophysica Acta. 1850: 1426-37. PMID 25857771 DOI: 10.1016/j.bbagen.2015.03.014  0.6
2015 Dansette PM, Levent D, Hessani A, Mansuy D. Bioactivation of Clopidogrel and Prasugrel: Factors Determining the Stereochemistry of the Thiol Metabolite Double Bond Chemical Research in Toxicology. 28: 1338-1345. DOI: 10.1021/acs.chemrestox.5b00133  1
2015 Ducassou L, Jonasson G, Dhers L, Pietrancosta N, Ramassamy B, Xu-Li Y, Loriot MA, Beaune P, Bertho G, Lombard M, Mansuy D, André F, Boucher JL. Expression in yeast, new substrates, and construction of a first 3D model of human orphan cytochrome P450 2U1: Interpretation of substrate hydroxylation regioselectivity from docking studies Biochimica Et Biophysica Acta - General Subjects. 1850: 1426-1437. DOI: 10.1016/j.bbagen.2015.03.014  1
2014 Decroos C, Boucher JL, Mansuy D, Xu-Li Y. Reactions of amino acids, peptides, and proteins with oxidized metabolites of tris(p-carboxyltetrathiaaryl)methyl radical EPR probes. Chemical Research in Toxicology. 27: 627-36. PMID 24564180 DOI: 10.1021/Tx400467P  0.44
2014 Bézière N, Hardy M, Poulhès F, Karoui H, Tordo P, Ouari O, Frapart YM, Rockenbauer A, Boucher JL, Mansuy D, Peyrot F. Metabolic stability of superoxide adducts derived from newly developed cyclic nitrone spin traps Free Radical Biology and Medicine. 67: 150-158. PMID 24161442 DOI: 10.1016/j.freeradbiomed.2013.10.812  1
2014 Decroos C, Boucher JL, Mansuy D, Xu-Li Y. Reactions of amino acids, peptides, and proteins with oxidized metabolites of tris(p-carboxyltetrathiaaryl)methyl radical EPR probes Chemical Research in Toxicology. 27: 627-636. DOI: 10.1021/tx400467p  1
2013 Decroos C, Balland V, Boucher JL, Bertho G, Xu-Li Y, Mansuy D. Toward stable electron paramagnetic resonance oximetry probes: Synthesis, characterization, and metabolic evaluation of new ester derivatives of a tris-(para-carboxyltetrathiaaryl)methyl (TAM) radical Chemical Research in Toxicology. 26: 1561-1569. PMID 24010758 DOI: 10.1021/Tx400250A  1
2013 Mansuy D. Metabolism of xenobiotics: Beneficial and adverse effects | Le métabolisme des xénobiotiques: effets béné fiques, effets néfastes Biologie Aujourd'Hui. 207: 33-37. PMID 23694723 DOI: 10.1051/jbio/2013003  1
2013 Dansette PM, Levent D, Hessani A, Bertho G, Mansuy D. Thiolactone sulfoxides as new reactive metabolites acting as bis-electrophiles: Implication in clopidogrel and prasugrel bioactivation Chemical Research in Toxicology. 26: 794-802. PMID 23527615 DOI: 10.1021/Tx400083B  1
2012 Bézière N, Decroos C, Mkhitaryan K, Kish E, Richard F, Bigot-Marchand S, Durand S, Cloppet F, Chauvet C, Corvol MT, Rannou F, Xu-Li Y, Mansuy D, Peyrot F, Frapart YM. First combined in vivo X-ray tomography and high-resolution molecular electron paramagnetic resonance (EPR) imaging of the mouse knee joint taking into account the disappearance kinetics of the EPR probe. Molecular Imaging. 11: 220-8. PMID 22554486 DOI: 10.2310/7290.2011.00042  1
2012 Messina P, Labbé E, Buriez O, Hillard EA, Vessières A, Hamels D, Top S, Jaouen G, Frapart YM, Mansuy D, Amatore C. Deciphering the activation sequence of ferrociphenol anticancer drug candidates Chemistry - a European Journal. 18: 6581-6587. PMID 22492462 DOI: 10.1002/Chem.201103378  1
2012 Soler N, Craescu CT, Gallay J, Frapart YM, Mansuy D, Raynal B, Baldacci G, Pastore A, Huang ME, Vernis L. A S-adenosylmethionine methyltransferase-like domain within the essential, Fe-S-containing yeast protein Dre2 Febs Journal. 279: 2108-2119. PMID 22487307 DOI: 10.1111/J.1742-4658.2012.08597.X  1
2012 Dansette PM, Rosi J, Debernardi J, Bertho G, Mansuy D. Metabolic activation of prasugrel: Nature of the two competitive pathways resulting in the opening of its thiophene ring Chemical Research in Toxicology. 25: 1058-1065. PMID 22482514 DOI: 10.1021/Tx3000279  1
2012 Salard-Arnaud I, Stuehr D, Boucher JL, Mansuy D. Spectroscopic, catalytic and binding properties of Bacillus subtilis NO synthase-like protein: Comparison with other bacterial and mammalian NO synthases Journal of Inorganic Biochemistry. 106: 164-171. PMID 22119809 DOI: 10.1016/J.Jinorgbio.2011.10.003  1
2012 Dansette PM, Rosi J, Bertho G, Mansuy D. Cytochromes P450 catalyze both steps of the major pathway of clopidogrel bioactivation, whereas paraoxonase catalyzes the formation of a minor thiol metabolite isomer Chemical Research in Toxicology. 25: 348-356. PMID 22103858 DOI: 10.1021/Tx2004085  1
2012 Mansuy D. Toxicology: A more multidisciplinary and mechanistic research, with implications in biology and chemistry | La toxicologie : une recherche de plus en plus multidisciplinaire et mécanistique, avec des retombées en biologie et en chimie Actualite Chimique. 81-82.  1
2011 Soler N, Delagoutte E, Miron S, Facca C, Baïlle D, d'Autreaux B, Craescu G, Frapart YM, Mansuy D, Baldacci G, Huang ME, Vernis L. Interaction between the reductase Tah18 and highly conserved Fe-S containing Dre2 C-terminus is essential for yeast viability Molecular Microbiology. 82: 54-67. PMID 21902732 DOI: 10.1111/J.1365-2958.2011.07788.X  1
2011 Dansette PM, Rosi J, Bertho G, Mansuy D. Paraoxonase-1 and clopidogrel efficacy. Nature Medicine. 17: 1040-1041; author re. PMID 21900914 DOI: 10.1038/Nm.2436  1
2011 Decroos C, Prangé T, Mansuy D, Boucher JL, Li Y. Unprecedented ipso aromatic nucleophilic substitution upon oxidative decarboxylation of tris(p-carboxyltetrathiaaryl)methyl (TAM) radicals: A new access to diversely substituted TAM radicals Chemical Communications. 47: 4805-4807. PMID 21412549 DOI: 10.1039/c1cc10426h  1
2011 Mansuy D. Brief historical overview and recent progress on cytochromes P450: Adaptation of aerobic organisms to their chemical environment and new mechanisms of prodrug bioactivation | Bref survol historique et progrès récents concernant les cytochromes P450 adaptation des organismes aérobies à leur environnement chimique et nouveaux mécanismes de bioactivation des médicaments Annales Pharmaceutiques Francaises. 69: 62-69. PMID 21296219 DOI: 10.1016/j.pharma.2010.11.001  1
2011 Lombard M, Salard I, Sari MA, Mansuy D, Buisson D. A new cytochrome P450 belonging to the 107L subfamily is responsible for the efficient hydroxylation of the drug terfenadine by Streptomyces platensis Archives of Biochemistry and Biophysics. 508: 54-63. PMID 21241658 DOI: 10.1016/j.abb.2011.01.008  1
2011 Mansuy D, Dansette PM. Sulfenic acids as reactive intermediates in xenobiotic metabolism Archives of Biochemistry and Biophysics. 507: 174-185. PMID 20869346 DOI: 10.1016/J.Abb.2010.09.015  1
2011 Dansette PM, Rosi J, Bertho G, Mansuy D. To the editor Nature Medicine. 17: 1040-1041. DOI: 10.1038/nm.2436  1
2010 Giroud C, Moreau M, Sagami I, Shimizu T, Frapart Y, Mansuy D, Boucher JL. Comparison of wild type neuronal nitric oxide synthase and its Tyr588Phe mutant towards various l-arginine analogues Journal of Inorganic Biochemistry. 104: 1043-1050. PMID 20630600 DOI: 10.1016/J.Jinorgbio.2010.06.001  1
2010 Decroos C, Li Y, Soltani A, Frapart Y, Mansuy D, Boucher JL. Oxidative decarboxylation of tris-(p-carboxyltetrathiaaryl)methyl radical EPR probes by peroxidases and related hemeproteins: intermediate formation and characterization of the corresponding cations. Archives of Biochemistry and Biophysics. 502: 74-80. PMID 20615385 DOI: 10.1016/j.abb.2010.07.002  1
2010 Dansette PM, Thébault S, Bertho G, Mansuy D. Formation and fate of a sulfenic acid intermediate in the metabolic activation of the antithrombotic prodrug prasugrel Chemical Research in Toxicology. 23: 1268-1274. PMID 20557086 DOI: 10.1021/Tx1001332  1
2010 Bézière N, Frapart Y, Rockenbauer A, Boucher JL, Mansuy D, Peyrot F. Metabolic stability of superoxide and hydroxyl radical adducts of a cyclic nitrone toward rat liver microsomes and cytosol: A stopped-flow ESR spectroscopy study Free Radical Biology and Medicine. 49: 437-446. PMID 20452418 DOI: 10.1016/j.freeradbiomed.2010.04.035  1
2009 Hamels D, Dansette PM, Hillard EA, Top S, Vessières A, Herson P, Jaouen G, Mansuy D. Ferrocenyl quinone methides as strong antiproliferative agents: Formation by metabolic and chemical oxidation of ferrocenyl phenols Angewandte Chemie - International Edition. 48: 9124-9126. PMID 19876986 DOI: 10.1002/Anie.200903768  1
2009 Decroos C, Li Y, Bertho G, Frapart Y, Mansuy D, Boucher JL. Oxidative and reductive metabolism of tris(p-carboxyltetrathiaaryl)methyl radicals by liver microsomes Chemical Research in Toxicology. 22: 1342-1350. PMID 19545126 DOI: 10.1021/Tx9001379  1
2009 Decroos C, Li Y, Bertho G, Frapart Y, Mansuy D, Boucher JL. Oxidation of tris-(p-carboxyltetrathiaaryl)methyl radical EPR probes: Evidence for their oxidative decarboxylation and molecular origin of their specific ability to react with O2 - Chemical Communications. 1416-1418. PMID 19259606 DOI: 10.1039/b819259f  1
2009 Dansette PM, Libraire J, Bertho G, Mansuy D. Metabolie oxidative cleavage of thioesters: Evidence for the formation of sulfenic acid intermediates in the bioactivation of the antithrombotic prodrugs ticlopidine and clopidogrel Chemical Research in Toxicology. 22: 369-373. PMID 19170597 DOI: 10.1021/Tx8004828  1
2008 Cottyn B, Acher F, Ramassamy B, Alvey L, Lepoivre M, Frapart Y, Stuehr D, Mansuy D, Boucher JL, Vichard D. Inhibitory effects of a series of 7-substituted-indazoles toward nitric oxide synthases: Particular potency of 1H-indazole-7-carbonitrile Bioorganic and Medicinal Chemistry. 16: 5962-5973. PMID 18502134 DOI: 10.1016/J.Bmc.2008.04.056  1
2008 Chandor A, Dijols S, Ramassamy B, Frapart Y, Mansuy D, Stuehr D, Helsby N, Boucher JL. Metabolic activation of the antitumor drug 5-(aziridin-1-yl)-2,4- dinitrobenzamide (CB1954) by NO synthases Chemical Research in Toxicology. 21: 836-843. PMID 18370414 DOI: 10.1021/Tx7004234  1
2008 Thibon A, Bartoli JF, Guillot R, Sainton J, Martinho M, Mansuy D, Banse F. Non-heme iron polyazadentate complexes as catalysts for aromatic hydroxylation by H2O2: Particular efficiency of tetrakis(2-pyridylmethyl)ethylenediamine-iron(II) complexes Journal of Molecular Catalysis a: Chemical. 287: 115-120. DOI: 10.1016/j.molcata.2008.03.006  1
2008 Mansuy D. Biocatalysis and substrate chemodiversity: Adaptation of aerobic living organisms to their chemical environment Catalysis Today. 138: 2-8. DOI: 10.1016/j.cattod.2008.04.028  1
2007 Lafite P, André F, Zeldin DC, Dansette PM, Mansuy D. Unusual regioselectivity and active site topology of human cytochrome P450 2J2 Biochemistry. 46: 10238-10247. PMID 17705402 DOI: 10.1021/Bi700876A  1
2007 Lafite P, Dijols S, Zeldin DC, Dansette PM, Mansuy D. Selective, competitive and mechanism-based inhibitors of human cytochrome P450 2J2 Archives of Biochemistry and Biophysics. 464: 155-168. PMID 17470359 DOI: 10.1016/J.Abb.2007.03.028  1
2007 Mansuy D, Lafite P. Great adaptability of the heme-cysteinate monooxygenases family to very diverse substrates and sophisticated reactions Journal of Porphyrins and Phthalocyanines. 11: 258-268. DOI: 10.1142/S108842460700031X  1
2007 Bochot C, Bartoli JF, Frapart Y, Dansette PM, Mansuy D, Battioni P. Synthesis and spectroscopic, electrochemical, and catalytic properties of a new manganese porphyrin bearing four positive charges close to the metal Journal of Molecular Catalysis a: Chemical. 263: 200-205. DOI: 10.1016/J.Molcata.2006.08.032  1
2007 Mansuy D. A brief history of the contribution of metalloporphyrin models to cytochrome P450 chemistry and oxidation catalysis Comptes Rendus Chimie. 10: 392-413. DOI: 10.1016/j.crci.2006.11.001  1
2007 Renner MW, Bochot C, Héroux A, Mansuy D, Battioni P. Structural, electrochemical, and spectroscopic properties of a class of dodecasubstituted iron porphyrins bearing four positive charges close to the metal European Journal of Inorganic Chemistry. 2426-2433. DOI: 10.1002/ejic.200601181  1
2006 Salard I, Mercey E, Rekka E, Boucher JL, Nioche P, Mikula I, Martasek P, Raman CS, Mansuy D. Analogies and surprising differences between recombinant nitric oxide synthase-like proteins from Staphylococcus aureus and Bacillus anthracis in their interactions with l-arginine analogs and iron ligands Journal of Inorganic Biochemistry. 100: 2024-2033. PMID 17084900 DOI: 10.1016/j.jinorgbio.2006.09.017  1
2006 Moreau M, Boucher JL, Mattioli TA, Stuehr DJ, Mansuy D, Santolini J. Differential effects of alkyl- and arylguanidines on the stability and reactivity of inducible NOS heme-dioxygen complexes Biochemistry. 45: 3988-3999. PMID 16548526 DOI: 10.1021/Bi051488P  1
2006 Lafite P, Dijols S, Buisson D, Macherey AC, Zeldin DC, Dansette PM, Mansuy D. Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2 Bioorganic and Medicinal Chemistry Letters. 16: 2777-2780. PMID 16495056 DOI: 10.1016/J.Bmcl.2006.02.004  1
2006 Lefèvre-Groboillot D, Boucher JL, Mansuy D, Stuehr DJ. Reactivity of the heme-dioxygen complex of the inducible nitric oxide synthase in the presence of alternative substrates Febs Journal. 273: 180-191. PMID 16367758 DOI: 10.1111/J.1742-4658.2005.05056.X  1
2005 Mansuy D. Metathesis and catalysis awarded | Métathèse et catalyse à l'honneur Medecine/Sciences. 21: 995-996. PMID 16274653 DOI: 10.1051/medsci/20052111995  1
2005 Dansette PM, Bertho G, Mansuy D. First evidence that cytochrome P450 may catalyze both S-oxidation and epoxidation of thiophene derivatives Biochemical and Biophysical Research Communications. 338: 450-455. PMID 16137656 DOI: 10.1016/J.Bbrc.2005.08.091  1
2005 Capeillere-Blandin C, Mathieu D, Mansuy D. Reduction of ferric haemoproteins by tetrahydropterins: A kinetic study Biochemical Journal. 392: 583-587. PMID 16050807 DOI: 10.1042/BJ20050437  1
2005 Beranova P, Chalupsky K, Kleschyov AL, Schott C, Boucher JL, Mansuy D, Munzel T, Muller B, Stoclet JC. Nω-hydroxy-L-arginine homologues and hydroxylamine as nitric oxide-dependent vasorelaxant agents European Journal of Pharmacology. 516: 260-267. PMID 15964563 DOI: 10.1016/j.ejphar.2005.04.021  1
2005 Lefèvre-Groboillot D, Boucher JL, Stuehr DJ, Mansuy D. Relationship between the structure of guanidines and N-hydroxyguanidines, their binding to inducible nitric oxide synthase (iNOS) and their iNOS-catalysed oxidation to NO Febs Journal. 272: 3172-3183. PMID 15955074 DOI: 10.1111/J.1742-4658.2005.04736.X  1
2005 Busnel O, Carreaux F, Carboni B, Pethe S, Goff SV, Mansuy D, Boucher JL. Synthesis and evaluation of new omega-borono-alpha-amino acids as rat liver arginase inhibitors. Bioorganic & Medicinal Chemistry. 13: 2373-9. PMID 15755639 DOI: 10.1016/j.bmc.2005.01.053  1
2005 Vadon-Legoff S, Dijols S, Mansuy D, Boucher JL. Improved and high yield synthesis of the potent arginase inhibitor: 2(S)-amino-6-boronohexanoic acid Organic Process Research and Development. 9: 677-679. DOI: 10.1021/Op050096N  1
2004 Melet A, Marques-Soares C, Schoch GA, Macherey AC, Jaouen M, Dansette PM, Sari MA, Johnson EF, Mansuy D. Analysis of human cytochrome P450 2C8 substrate specificity using a substrate pharmacophore and site-directed mutants Biochemistry. 43: 15379-15392. PMID 15581350 DOI: 10.1021/Bi0489309  1
2004 Mansuy D, Boucher JL. Alternative nitric oxide-producing substrates for no synthases Free Radical Biology and Medicine. 37: 1105-1121. PMID 15451052 DOI: 10.1016/j.freeradbiomed.2004.06.031  1
2004 Gerald D, Berra E, Frapart YM, Chan DA, Giaccia AJ, Mansuy D, Pouysségur J, Yaniv M, Mechta-Grigoriou F. JunD reduces tumor angiogenesis by protecting cells from oxidative stress Cell. 118: 781-794. PMID 15369676 DOI: 10.1016/J.Cell.2004.08.025  1
2004 Cama E, Pethe S, Boucher JL, Han S, Emig FA, Ash DE, Viola RE, Mansuy D, Christianson DW. Inhibitor coordination interactions in the binuclear manganese cluster of arginase. Biochemistry. 43: 8987-99. PMID 15248756 DOI: 10.1021/Bi0491705  1
2004 Moreau M, Takahashi H, Sari MA, Boucher JL, Sagami I, Shimizu T, Mansuy D. Importance of valine 567 in substrate recognition and oxidation by neuronal nitric oxide synthase Journal of Inorganic Biochemistry. 98: 1200-1209. PMID 15219986 DOI: 10.1016/J.Jinorgbio.2004.03.015  1
2004 Mathieu D, Frapart YM, Bartoli JF, Boucher JL, Battioni P, Mansuy D. Very general formation of tetrahydropterin cation radicals during reaction of iron porphyrins with tetrahydropterins: model for the corresponding NO-synthase reaction. Chemical Communications (Cambridge, England). 54-5. PMID 14737329 DOI: 10.1039/b312441j  0.56
2004 Mathieu D, Bartoli JF, Battioni P, Mansuy D. Monooxygenation of aromatic compounds by dioxygen with bioinspired systems using non-heme iron catalysts and tetrahydropterins: Comparison with other reducing agents and interesting regioselectivity favouring meta-hydroxylation Tetrahedron. 60: 3855-3862. DOI: 10.1016/j.tet.2004.03.006  1
2004 Balland V, Mathieu D, Pons-Y-Moll N, Bartoli JF, Banse F, Battioni P, Girerd JJ, Mansuy D. Non-heme iron polyazadentate complexes as catalysts for oxidations by H2O2: Particular efficiency in aromatic hydroxylations and beneficial effects of a reducing agent Journal of Molecular Catalysis a: Chemical. 215: 81-87. DOI: 10.1016/j.molcata.2004.01.015  1
2004 Maldotti A, Molinari A, Vitali I, Ganzaroli E, Battioni P, Mathieu D, Mansuy D. Oxidation of N-4-chlorophenyl-N′-hydroxyguanidine to N-(4-chlorophenyl)urea and nitric oxide by photoexcited iron porphyrins European Journal of Inorganic Chemistry. 3127-3135. DOI: 10.1002/ejic.200400056  1
2004 Mansuy D, Mathieu D, Battioni P, Boucher JL. Reactions between iron porphyrins and tetrahydropterins Journal of Porphyrins and Phthalocyanines. 8: 265-278.  1
2004 Balland V, Charlot MF, Banse F, Girerd JJ, Mattioli TA, Bill E, Bartoli JF, Battioni P, Mansuy D. Spectroscopic Characterization of an FeIV Intermediate Generated by Reaction of XO- (X = Cl, Br) with an FeII Complex Bearing a Pentadentate Non-Porphyrinic Ligand - Hydroxylation and Epoxidation Activity European Journal of Inorganic Chemistry. 301-308.  1
2004 Mathieu D, Frapart YM, Bartoli JF, Boucher JL, Battioni P, Mansuy D. Very general formation of tetrahydropterin cation radicals during reaction of iron porphyrins with tetrahydropterins: Model for the corresponding NO-synthase reaction Chemical Communications. 10: 54-55.  1
2003 Ask K, Dijols S, Giroud C, Casse L, Frapart YM, Sari MA, Kim KS, Stuehr DJ, Mansuy D, Camus P, Boucher JL. Reduction of Nilutamide by NO Synthases: Implications for the Adverse Effects of This Nitroaromatic Antiandrogen Drug Chemical Research in Toxicology. 16: 1547-1554. PMID 14680368 DOI: 10.1021/Tx0340910  1
2003 Pfister SL, Spitzbarth N, Zeldin DC, Lafite P, Mansuy D, Campbell WB. Rabbit aorta converts 15-HPETE to trihydroxyeicosatrienoic acids: Potential role of cytochrome P450 Archives of Biochemistry and Biophysics. 420: 142-152. PMID 14622984 DOI: 10.1016/j.abb.2003.09.026  1
2003 Stevens JM, Belghazi M, Jaouen M, Bonnet D, Schmitter JM, Mansuy D, Sari MA, Artaud I. Post-translational modification of Rhodococcus R312 and Comamonas NI1 nitrile hydratases Journal of Mass Spectrometry. 38: 955-961. PMID 14505323 DOI: 10.1002/jms.509  1
2003 Wester MR, Johnson EF, Marques-Soares C, Dijols S, Dansette PM, Mansuy D, Stout CD. Structure of mammalian cytochrome P450 2C5 complexed with diclofenac at 2.1 Å resolution: Evidence for an induced fit model of substrate binding Biochemistry. 42: 9335-9345. PMID 12899620 DOI: 10.1021/Bi034556L  1
2003 Wester MR, Johnson EF, Marques-Soares C, Dansette PM, Mansuy D, Stout CD. Structure of a substrate complex of mammalian cytochrome P450 2C5 at 2.3 Å resolution: Evidence for multiple substrate binding modes Biochemistry. 42: 6370-6379. PMID 12767218 DOI: 10.1021/Bi0273922  1
2003 Marques-Soares C, Dijols S, Macherey AC, Wester MR, Johnson EF, Dansette PM, Mansuy D. Sulfaphenazole derivatives as tools for comparing cytochrome P450 2C5 and human cytochromes P450 2Cs: Identification of a new high affinity substrate common to those enzymes Biochemistry. 42: 6363-6369. PMID 12767217 DOI: 10.1021/Bi027391+  1
2003 Stevens JM, Saroja NR, Jaouen M, Belghazi M, Schmitter JM, Mansuy D, Artaud I, Sari MA. Chaperone-assisted expression, purification, and characterization of recombinant nitrile hydratase NI1 from Comamonas testosteroni Protein Expression and Purification. 29: 70-76. PMID 12729727 DOI: 10.1016/S1046-5928(03)00008-1  1
2003 Lefèvre-Groboillot D, Frapart Y, Desbois A, Zimmermann JL, Boucher JL, Gorren AC, Mayer B, Stuehr DJ, Mansuy D. Two modes of binding of N-hydroxyguanidines to NO synthases: first evidence for the formation of iron-N-hydroxyguanidine complexes and key role of tetrahydrobiopterin in determining the binding mode. Biochemistry. 42: 3858-67. PMID 12667076 DOI: 10.1021/Bi0272407  1
2003 Ricoux R, Boucher JL, Mandon D, Frapart YM, Henry Y, Mansuy D, Mahy JP. Microperoxidase 8 catalysed nitrogen oxides formation from oxidation of n-hydroxyguanidines by hydrogen peroxide European Journal of Biochemistry. 270: 47-55. PMID 12492474 DOI: 10.1046/J.1432-1033.2003.03358.X  1
2003 Melet A, Assrir N, Jean P, Lopez-Garcia MP, Marques-Soares C, Jaouen M, Dansette PM, Sari MA, Mansuy D. Substrate selectivity of human cytochrome P450 2C9: Importance of residues 476, 365, and 114 in recognition of diclofenac and sulfaphenazole and in mechanism-based inactivation by tienilic acid Archives of Biochemistry and Biophysics. 409: 80-91. PMID 12464247 DOI: 10.1016/S0003-9861(02)00548-9  1
2003 Takahashi H, Sato Y, Moreau M, Sari MA, Boucher JL, Mansuy D, Sagami I, Shimizu T. Critical Role of Val567 in Substrate Recognition by Neuronal Nitric Oxide Synthase for NO Formation Activity Chemistry Letters. 32: 998-999. DOI: 10.1246/Cl.2003.998  1
2002 Barkigia KM, Palacio M, Sun Y, Nogues M, Renner MW, Varret F, Battioni P, Mansuy D, Fajer J. Air-stable, electron-deficient Fe(II) catalytic porphyrins. Characterization and molecular structures of rare high spin Fe(II) hexacoordinated porphyrins Inorganic Chemistry. 41: 5647-5649. PMID 12401065 DOI: 10.1021/Ic025869S  1
2002 Vetrovsky P, Boucher JL, Schott C, Beranova P, Chalupsky K, Callizot N, Muller B, Entlicher G, Mansuy D, Stoclet JC. Involvement of NO in the endothelium-independent relaxing effects of Nω-hydroxy-L-arginine and other compounds bearing a C=NOH function in the rat aorta Journal of Pharmacology and Experimental Therapeutics. 303: 823-830. PMID 12388669 DOI: 10.1124/Jpet.102.038612  1
2002 Treiber A, Dansette PM, Mansuy D. Mechanism of the aromatic hydroxylation of thiophene by acid-catalyzed peracid oxidation. The Journal of Organic Chemistry. 67: 7261-6. PMID 12375952 DOI: 10.1021/Jo0202177  1
2002 Mansuy D, Boucher JL. Oxidation of N-hydroxyguanidines by cytochromes P450 and no-synthases and formation of nitric oxide Drug Metabolism Reviews. 34: 593-606. PMID 12214669 DOI: 10.1081/DMR-120005661  1
2002 Dijols S, Boucher JL, Lepoivre M, Lefevre-Groboillot D, Moreau M, Frapart Y, Rekka E, Meade AL, Stuehr DJ, Mansuy D. First non-α-amino acid guanidines acting as efficient NO precursors upon oxidation by NO-synthase II or activated mouse macrophages Biochemistry. 41: 9286-9292. PMID 12135349 DOI: 10.1021/Bi025691L  1
2002 Barkigia KM, Battioni P, Riou V, Mansuy D, Fajer J. Supramolecular self-assembly of a fluorinated Zn porphyrin. Molecular structure of a two-dimensional network of amine-functionalized, hexacoordinated Zn porphyrins. Chemical Communications (Cambridge, England). 956-7. PMID 12123066  0.56
2002 Pethe S, Boucher JL, Mansuy D. Interaction of anions with rat liver arginase: Specific inhibitory effects of fluoride Journal of Inorganic Biochemistry. 88: 397-402. PMID 11897356 DOI: 10.1016/S0162-0134(01)00417-2  1
2002 De Lauzon S, Mansuy D, Mahy JP. Coordination chemistry of iron(III)-porphyrin-antibody complexes influence on the peroxidase activity of the axial coordination of an imidazole on the iron atom European Journal of Biochemistry. 269: 470-480. PMID 11856305 DOI: 10.1046/j.0014-2956.2001.02670.x  1
2002 Renodon-Cornière A, Dijols S, Perollier C, Lefevre-Groboillot D, Boucher JL, Attias R, Sari MA, Stuehr D, Mansuy D. N-aryl N′-hydroxyguanidines, a new class of NO-donors after selective oxidation by nitric oxide synthases: Structure-activity relationship Journal of Medicinal Chemistry. 45: 944-954. PMID 11831907 DOI: 10.1021/Jm011006H  1
2002 Palacio M, Juillard A, Leduc P, Battioni P, Mansuy D. One-pot dodecanitration of Zn(II) and Ni(II) meso-tetrakis-(2,6-dichlorophenyl) porphyrin, and extreme redox properties of the obtained complexes Journal of Organometalic Chemistry. 643: 522-524. DOI: 10.1016/S0022-328X(01)01382-1  1
2002 Chatel S, Chauvin AS, Tuchagues JP, Leduc P, Bill E, Chottard JC, Mansuy D, Artaud I. Structural and spectroscopic characterization of a five-coordinate {Fe(NO)}6 complex derived from an iron complex with carboxamido N and thiolato S donors Inorganica Chimica Acta. 336: 19-28. DOI: 10.1016/S0020-1693(02)00818-6  1
2002 Bartoli JF, Lambert F, Morgenstern-Badarau I, Battioni P, Mansuy D. Unusual efficiency of a non-heme iron complex as catalyst for the hydroxylation of aromatic compounds by hydrogen peroxide: Comparison with iron porphyrins Comptes Rendus Chimie. 5: 263-266.  1
2002 Barkigia KM, Battioni P, Riou V, Mansuy D, Fajer J. Supramolecular self-assembly of a fluorinated Zn porphyrin. Molecular structure of a two-dimensional network of amine-functionalized, hexacoordinated Zn porphyrins Chemical Communications. 956-957.  1
2001 Bartoli JF, Barch KL, Palacio M, Battioni P, Mansuy D. Iron polynitroporphyrins bearing up to eight β-nitro groups as interesting new catalysts for H2O2-dependent hydrocarbon oxidation: Unusual regioselectivity in hydroxylation of alkoxybenzenes Chemical Communications. 1718-1719. PMID 12240281 DOI: 10.1039/B105101F  1
2001 Ricoux R, Boucher JL, Mansuy D, Mahy JP. Microperoxidase 8(MP8) as a convenient model for hemoproteins: Formation and characterisation of new iron(II)-nitrosoalkane complexes of biological relevance Advances in Experimental Medicine and Biology. 500: 149-152. PMID 11764928  1
2001 Ha-Duong NT, Dijols S, Macherey AC, Dansette PM, Mansuy D. Inhibition by ticlopidine and its derivatives of human liver cytochrome P450. Mechanism-based inactivation of CYP 2C19 by ticlopidine Advances in Experimental Medicine and Biology. 500: 145-148. PMID 11764927 DOI: 10.1007/978-1-4615-0667-6_18  1
2001 Belghazi M, Jean P, Poli S, Schmitter JM, Mansuy D, Dansette PM. Use of isotopes and LC-MS-ESI-TOF for mechanistic studies of tienilic acid metabolic activation Advances in Experimental Medicine and Biology. 500: 139-144. PMID 11764926  1
2001 Ha-Duong NT, Dijols S, Marques-Soares C, Minoletti C, Dansette PM, Mansuy D. Synthesis of sulfaphenazole derivatives and their use as inhibitors and tools for comparing the active sites of human liver cytochromes P450 of the 2C subfamily Journal of Medicinal Chemistry. 44: 3622-3631. PMID 11606127 DOI: 10.1021/Jm010861Y  1
2001 Morgan ET, Ullrich V, Daiber A, Schmidt P, Takaya N, Shoun H, Mcgiff JC, Oyekan A, Hanke CJ, Campbell WB, Park CS, Kang JS, Yi HG, Cha YN, Mansuy D, et al. Cytochromes P450 and flavin monooxygenases - Targets and sources of nitric oxide Drug Metabolism and Disposition. 29: 1366-1376. PMID 11602511  1
2001 Ha-Duong NT, Marques-Soares C, Dijols S, Sari MA, Dansette PM, Mansuy D. Interaction of new sulfaphenazole derivatives with human liver cytochrome P450 2Cs: Structural determinants required for selective recognition by CYP 2C9 and for inhibition of human CYP 2Cs Archives of Biochemistry and Biophysics. 394: 189-200. PMID 11594733 DOI: 10.1006/Abbi.2001.2511  1
2001 Ha-Duong NT, Dijols S, Macherey AC, Goldstein JA, Dansette PM, Mansuy D. Ticlopidine as a selective mechanism-based inhibitor of human cytochrome P450 2C19 Biochemistry. 40: 12112-12122. PMID 11580286 DOI: 10.1021/Bi010254C  1
2001 Dijols S, Perollier C, Lefevre-Groboillot D, Pethe S, Attias R, Boucher JL, Stuehr DJ, Mansuy D. Oxidation of Nω-hydroxyarginine analogues by NO-synthase: The simple, non amino acid N-butyl N′-hydroxyguanidine is almost as efficient an NO precursor as Nω-hydroxyarginine Journal of Medicinal Chemistry. 44: 3199-3202. PMID 11563918 DOI: 10.1021/jm0155446  1
2001 Lefevre-Groboillot D, Dijols S, Boucher JL, Mahy JP, Ricoux R, Desbois A, Zimmermann JL, Mansuy D. N-hydroxyguanidines as new heme ligands: UV-visible, EPR, and resonance Raman studies of the interaction of various compounds bearing a C=NOH function with microperoxidase-8 Biochemistry. 40: 9909-9917. PMID 11502185 DOI: 10.1021/Bi010561I  1
2001 Bonnet D, Stevens JM, Alves de Sousa R, Sari MA, Mansuy D, Artaud I. New inhibitors of iron-containing nitrile hydratases Journal of Biochemistry. 130: 227-233. PMID 11481039  1
2001 Ricoux R, Boucher JL, Mansuy D, Mahy JP. Microperoxidase 8 catalyzed nitration of phenol by nitrogen dioxide radicals European Journal of Biochemistry. 268: 3783-3788. PMID 11432746 DOI: 10.1046/j.1432-1327.2001.02288.x  1
2001 Rat M, Alves De Sousa R, Vaissermann J, Leduc P, Mansuy D, Artaud I. Clean oxidation of thiolates to sulfinates in a four-coordinate CoIII complex with a mixed carboxamido N-thiolato S donor set: Relevance to nitrile hydratase Journal of Inorganic Biochemistry. 84: 207-213. PMID 11374583  1
2001 Vadon-Le Goff S, Delaforge M, Boucher JL, Janosik M, Kraus JP, Mansuy D. Coordination chemistry of the heme in cystathionine β-synthase: Formation of iron(II)-isonitrile complexes Biochemical and Biophysical Research Communications. 283: 487-492. PMID 11327727 DOI: 10.1006/bbrc.2001.4807  1
2001 Moali C, Boucher JL, Renodon-Corniere A, Stuehr DJ, Mansuy D. Oxidations of N(omega)-hydroxyarginine analogues and various N-hydroxyguanidines by NO synthase II: key role of tetrahydrobiopterin in the reaction mechanism and substrate selectivity. Chemical Research in Toxicology. 14: 202-10. PMID 11258969 DOI: 10.1021/Tx0001068  1
2001 Cox JD, Cama E, Colleluori DM, Pethe S, Boucher JL, Mansuy D, Ash DE, Christianson DW. Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase. Biochemistry. 40: 2689-701. PMID 11258880 DOI: 10.1021/Bi002318+  1
2001 Bonnet D, Leduc P, Bill E, Chottard G, Mansuy D, Artaud I. CoII complexes with mixed amino-N and thiolato-S donor sets - Structural characterization and electronic properties of a stable bis(μ-thiolato)-bridged binuclear CoII complex European Journal of Inorganic Chemistry. 1449-1456.  1
2000 Ricoux R, Boucher JL, Mansuy D, Mahy JP. Formation of iron(II)-nitrosoalkane complexes: a new activity of microperoxidase 8. Biochemical and Biophysical Research Communications. 278: 217-23. PMID 11071875 DOI: 10.1006/bbrc.2000.3785  1
2000 Chatel S, Rat M, Dijols S, Leduc P, Tuchagues JP, Mansuy D, Artaud I. Toward model complexes of Co-containing nitrile hydratases: synthesis, complete characterization and reactivity toward ligands such as CN- and NO of the first square planar CoIII complex with two different carboxamido nitrogens and two thiolato sulfur donors. Journal of Inorganic Biochemistry. 80: 239-46. PMID 11001095 DOI: 10.1016/S0162-0134(00)00075-1  1
2000 Moali C, Brollo M, Custot J, Sari MA, Boucher JL, Stuehr DJ, Mansuy D. Recognition of alpha-amino acids bearing various C=NOH functions by nitric oxide synthase and arginase involves very different structural determinants. Biochemistry. 39: 8208-18. PMID 10889028 DOI: 10.1021/Bi992992V  1
2000 Bartoli JF, Mouries-Mansuy V, Le Barch-Ozette K, Palacio M, Battioni P, Mansuy D. New manganese β-polynitroporphyrins as particularly efficient catalysts for biomimetic hydroxylation of aromatic compounds with H2O2 Chemical Communications. 827-828. DOI: 10.1039/B001776K  1
2000 Molinari A, Amadelli R, Antolini L, Maldotti A, Battioni P, Mansuy D. Phororedox and photocatalytic processes on Fe(III)-porphyrin surface modified nanocrystalline TiO2 Journal of Molecular Catalysis a: Chemical. 158: 521-531. DOI: 10.1016/S1381-1169(99)00446-X  1
2000 Haber J, Iwanejko R, Połtowicz J, Battioni P, Mansuy D. Pernitrated metalloporphyrins as catalysts in oxidation with magnesium monoperoxophthalate. Part II. Epoxidation of linear olefins Journal of Molecular Catalysis a: Chemical. 152: 117-120. DOI: 10.1016/S1381-1169(99)00270-8  1
2000 Haber J, Iwanejko R, Połtowicz J, Battioni P, Mansuy D. Pernitrated metalloporphyrins as catalysts in oxidation with magnesium monoperoxophthalate. I. Epoxidation of cyclic olefins Journal of Molecular Catalysis a: Chemical. 152: 111-115. DOI: 10.1016/S1381-1169(99)00269-1  1
2000 Palacio M, Mansuy-Mouries V, Loire G, Le Barch-Ozette K, Leduc P, Barkigia KM, Fajer J, Battioni P, Mansuy D. A new general method for selective β-polynitration of porphyrins; preparation and redox properties of Zn-porphyrins bearing one through to eight β-nitro substituents and X-ray structure of the first Zn β-pernitro porphyrin Chemical Communications. 1907-1908.  1
2000 Othman S, Mansuy-Mouries V, Bensoussan C, Battioni P, Mansuy D. Hydroxylation of diclofenac: An illustration of the complementary roles of biomimetic metalloporphyrin catalysts and yeasts expressing human cytochromes P450 in drug metabolism studies Comptes Rendus De L'Academie Des Sciences - Series Iic: Chemistry. 3: 751-755.  1
2000 Vadon-Le Goff S, Boucher JL, Mansuy D. Oxidation of arylamidoximes by various chemical and biomimetic systems: Comparison with their oxidations by hemeproteins Comptes Rendus De L'Academie Des Sciences - Series Iic: Chemistry. 3: 785-792.  1
1999 Tenu JP, Lepoivre M, Moali C, Brollo M, Mansuy D, Boucher JL. Effects of the new arginase inhibitor N(omega)-hydroxy-nor-L-arginine on NO synthase activity in murine macrophages. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 3: 427-38. PMID 10637120 DOI: 10.1006/Niox.1999.0255  1
1999 Mancy A, Antignac M, Minoletti C, Dijols S, Mouries V, Duong NT, Battioni P, Dansette PM, Mansuy D. Diclofenac and its derivatives as tools for studying human cytochromes P450 active sites: particular efficiency and regioselectivity of P450 2Cs. Biochemistry. 38: 14264-70. PMID 10572000 DOI: 10.1021/Bi991195U  1
1999 Clement B, Boucher JL, Mansuy D, Harsdorf A. Microsomal formation of nitric oxide and cyanamides from non-physiological N-hydroxyguanidines: N-hydroxydebrisoquine as a model substrate. Biochemical Pharmacology. 58: 439-45. PMID 10424762 DOI: 10.1016/S0006-2952(99)00102-1  1
1999 Minoletti C, Dijols S, Dansette PM, Mansuy D. Comparison of the substrate specificities of human liver cytochrome P450s 2C9 and 2C18: application to the design of a specific substrate of CYP 2C18. Biochemistry. 38: 7828-36. PMID 10387023 DOI: 10.1021/Bi9903289  1
1999 Renodon-Cornière A, Boucher JL, Dijols S, Stuehr DJ, Mansuy D. Efficient formation of nitric oxide from selective oxidation of N-aryl N'-hydroxyguanidines by inducible nitric oxide synthase. Biochemistry. 38: 4663-8. PMID 10200153 DOI: 10.1021/Bi982930P  1
1999 Bonierbale E, Valadon P, Pons C, Desfosses B, Dansette PM, Mansuy D. Opposite behaviors of reactive metabolites of tienilic acid and its isomer toward liver proteins: use of specific anti-tienilic acid-protein adduct antibodies and the possible relationship with different hepatotoxic effects of the two compounds. Chemical Research in Toxicology. 12: 286-96. PMID 10077492 DOI: 10.1021/Tx980136Z  1
1999 de Lauzon S, Desfosses B, Mansuy D, Mahy JP. Studies of the reactivity of artificial peroxidase-like hemoproteins based on antibodies elicited against a specifically designed ortho-carboxy substituted tetraarylporphyrin. Febs Letters. 443: 229-34. PMID 9989611 DOI: 10.1016/S0014-5793(98)01703-7  1
1998 Dansette PM, Bonierbale E, Minoletti C, Beaune PH, Pessayre D, Mansuy D. Drug-induced immunotoxicity. European Journal of Drug Metabolism and Pharmacokinetics. 23: 443-51. PMID 10323325 DOI: 10.1007/Bf03189993  1
1998 Mahy JP, Desfosses B, de Lauzon S, Quilez R, Desfosses B, Lion L, Mansuy D. Hemoabzymes. Different strategies for obtaining artificial hemoproteins based on antibodies. Applied Biochemistry and Biotechnology. 75: 103-27. PMID 10214700  1
1998 Mansuy D. The great diversity of reactions catalyzed by cytochromes P450. Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology. 121: 5-14. PMID 9972447 DOI: 10.1016/S0742-8413(98)10026-9  1
1998 Jousserandot A, Boucher JL, Henry Y, Niklaus B, Clement B, Mansuy D. Microsomal cytochrome P450 dependent oxidation of N-hydroxyguanidines, amidoximes, and ketoximes: mechanism of the oxidative cleavage of their C=N(OH) bond with formation of nitrogen oxides. Biochemistry. 37: 17179-91. PMID 9860831 DOI: 10.1021/Bi981175C  1
1998 De Lauzon S, Quilez R, Lion L, Desfosses B, Desfosses B, Lee I, Sari MA, Benkovic SJ, Mansuy D, Mahy JP. Active site topology of artificial peroxidase-like hemoproteins based on antibodies constructed from a specifically designed ortho-carboxy-substituted tetraarylporphyrin. European Journal of Biochemistry / Febs. 257: 121-30. PMID 9799110 DOI: 10.1046/J.1432-1327.1998.2570121.X  1
1998 Sari MA, Moali C, Boucher JL, Jaouen M, Mansuy D. Detection of a nitric oxide synthase possibly involved in the regulation of the Rhodococcus sp R312 nitrile hydratase. Biochemical and Biophysical Research Communications. 250: 364-8. PMID 9753635 DOI: 10.1006/bbrc.1998.9320  1
1998 Moali C, Boucher JL, Sari MA, Stuehr DJ, Mansuy D. Substrate specificity of NO synthases: detailed comparison of L-arginine, homo-L-arginine, their N omega-hydroxy derivatives, and N omega-hydroxynor-L-arginine. Biochemistry. 37: 10453-60. PMID 9671515 DOI: 10.1021/Bi980742T  1
1998 Renodon A, Boucher JL, Wu C, Gachhui R, Sari MA, Mansuy D, Stuehr D. Formation of nitric oxide synthase-iron(II) nitrosoalkane complexes: Severe restriction of access to the iron(II) site in the presence of tetrahydrobiopterin Biochemistry. 37: 6367-6374. PMID 9572852 DOI: 10.1021/Bi972297S  1
1998 Scheller FW, Kleinjung F, Bier FF, Makower A, Neumann B, Wollenberger U, Kurochkin I, Eremenko A, Barmin A, Klußmann S, Fürste JP, Erdmann VA, Mansuy D. New recognition elements in biosensing Annals of the New York Academy of Sciences. 864: 37-45. DOI: 10.1111/j.1749-6632.1998.tb10286.x  1
1998 Deniaud D, Spyroulias GA, Bartoli JF, Battioni P, Mansuy D, Pinel C, Odobel F, Bujoli B. Shape selectivity for alkane hydroxylation with a new class of phosphonate-based heterogenised manganese porphyrins New Journal of Chemistry. 22: 901-905. DOI: 10.1039/A709254G  1
1998 Kopf MA, Varech D, Tuchagues JP, Mansuy D, Artaud I. New intermediate-spin chloroiron(III) complex with a mixed nitrogen-sulfur co-ordination sphere Journal of the Chemical Society - Dalton Transactions. 991-998. DOI: 10.1039/A706664C  1
1998 Hart-Davis J, Battioni P, Boucher JL, Mansuy D. New catalytic properties of iron porphyrins: Model systems for cytochrome P450-catalyzed dehydration of aldoximes Journal of the American Chemical Society. 120: 12524-12530. DOI: 10.1021/Ja981805Y  1
1998 Pouzet P, Erdelmeier I, Dansette PM, Mansuy D. Synthesis of (4-chlorophenyl)-(1-oxo-1λ4-benzo[b]thien-2-yl)methanone and study of its reactivity towards sulfur- and oxygen-containing nucleophiles Tetrahedron. 54: 14811-14824. DOI: 10.1016/S0040-4020(98)00929-6  1
1998 Nastri F, Lombardi A, Morelli G, Pedone C, Pavone V, Chottard G, Battioni P, Mansuy D. Hemoprotein models based on a covalent helix-heme-helix sandwich. 3. Coordination properties, reactivity and catalytic application of Fe(III)- and Fe(II)-mimochrome I Journal of Biological Inorganic Chemistry. 3: 671-681. DOI: 10.1007/s007750050281  1
1998 Ozette K, Battioni P, Leduc P, Bartoli JF, Mansuy D. A new manganese-β-heptanitro-porphyrin with extreme redox potentials: Spectral, electrochemical and catalytic properties Inorganica Chimica Acta. 272: 4-6.  1
1997 Renodon A, Boucher JL, Sari MA, Delaforge M, Ouazzani J, Mansuy D. Strong inhibition of neuronal nitric oxide synthase by the calmodulin antagonist and anti-estrogen drug tamoxifen Biochemical Pharmacology. 54: 1109-1114. PMID 9464453 DOI: 10.1016/S0006-2952(97)00316-X  1
1997 Crichton RR, Soruco JA, Roland F, Michaux MA, Gallois B, Précigoux G, Mahy JP, Mansuy D. Remarkable ability of horse spleen apoferritin to demetallate hemin and to metallate protoporphyrin IX as a function of pH Biochemistry. 36: 15049-15054. PMID 9398231 DOI: 10.1021/Bi9709147  1
1997 Poli-Scaife S, Attias R, Dansette PM, Mansuy D. The substrate binding site of human liver cytochrome P450 2C9: An NMR study Biochemistry. 36: 12672-12682. PMID 9335524 DOI: 10.1021/Bi970527X  1
1997 McClure JE, Baudouin L, Mansuy D, Marzilli LG. Interactions of DNA with a new electron-deficient tentacle porphyrin: meso-tetrakis[2,3,5,6-tetrafluoro-4-(2-t rimethylammoniumethyl-amine)phenyl]porphy rin. Biopolymers. 42: 203-17. PMID 9234999 DOI: 10.1002/(SICI)1097-0282(199708)42:2<203::AID-BIP9>3.0.CO;2-R  1
1997 Mansuy D. Molecular structure and hepatotoxicity: Compared data about two closely related thiophene compounds Journal of Hepatology, Supplement. 26: 22-25. PMID 9204406  1
1997 Bonnet D, Artaud I, Moali C, Pétré D, Mansuy D. Highly efficient control of iron-containing nitrile hydratases by stoichiometric amounts of nitric oxide and light Febs Letters. 409: 216-220. PMID 9202148 DOI: 10.1016/S0014-5793(97)00511-5  1
1997 Renodon A, Boucher JL, Sari MA, Delaforge M, Ouazzani J, Mansuy D. Bromocriptine is a strong inhibitor of brain nitric oxide synthase: Possible consequences for the origin of its therapeutic effects Febs Letters. 406: 33-36. PMID 9109381 DOI: 10.1016/S0014-5793(97)00232-9  1
1997 Custot J, Moali C, Brollo M, Boucher JL, Delaforge M, Mansuy D, Tenu JP, Zimmermann JL. The new α-amino acid Nω-hydroxy-nor-L-arginine: A high-affinity inhibitor of arginase well adapted to bind to its manganese cluster Journal of the American Chemical Society. 119: 4086-4087. DOI: 10.1021/ja970285o  1
1997 Treiber A, Dansette PM, El Amri H, Girault JP, Ginderow D, Mornon JP, Mansuy D. Chemical and biological oxidation of thiophene: Preparation and complete characterization of thiophene S-oxide dimers and evidence for thiophene S-oxide as an intermediate in thiophene metabolism in vivo and in vitro Journal of the American Chemical Society. 119: 1565-1571. DOI: 10.1021/Ja962466G  1
1997 Mansuy D, Jean P, Pothicr J, Dansette P, Viari A. Automated multiple analysis of protein structures: application to homology modeling of cytochromes P450 Faseb Journal. 11: A778. DOI: 10.1002/(SICI)1097-0134(199707)28:3<388::AID-PROT9>3.0.CO;2-8  1
1997 Pouzet P, Erdelmeier I, Ginderow D, Mornon JP, Dansette PM, Mansuy D. Thiophene 1-Oxides. V [1], [2], [3], [4]. Comparison of the Crystal Structures and Thiophene Ring Aromaticity of 2,5-Diphenylthiophene, its Sulfoxide and Sulfone Journal of Heterocyclic Chemistry. 34: 1567-1574.  1
1997 Thellend A, Battioni P, Sanderson W, Mansuy D. Oxidation of N-heterocycles by H2O2 catalyzed by a Mn-porphyrin: An easy access to N-oxides under mild conditions Synthesis. 1387-1388.  1
1997 Mansuy D. Topology of the active sites of human cytochromes P450 of the 2C subfamily Faseb Journal. 11: A772.  1
1996 Beaune PH, Lecoeur S, Bourdi M, Gauffre A, Belloc C, Dansette P, Mansuy D. Anti-cytochrome p450 autoantibodies in drug-induced disease European Journal of Haematology, Supplement. 57: 89-92. PMID 8987248 DOI: 10.1111/J.1600-0609.1996.Tb01652.X  1
1996 Mancy A, Dijol S, Poli S, Guengerich FP, Mansuy D. Interaction of sulfaphenazole derivatives with human liver cytochromes P450 2C: Molecular origin of the specific inhibitory effects of sulfaphenazole on CYP 2C9 and consequences for the substrate binding site topology of CYP 2C9 Biochemistry. 35: 16205-16212. PMID 8973193 DOI: 10.1021/Bi961950T  1
1996 Valadon P, Dansette PM, Girault JP, Amar C, Mansuy D. Thiophene sulfoxides as reactive metabolites: Formation upon microsomal oxidation of a 3-aroylthiophene and fate in the presence of nucleophiles in vitro and in vivo Chemical Research in Toxicology. 9: 1403-1413. PMID 8951246 DOI: 10.1021/Tx9601622  1
1996 Jean P, Lopez-Garcia P, Dansette P, Mansuy D, Goldstein JL. Oxidation of tienilic acid by human yeast-expressed cytochromes P-450 2C8, 2C9, 2C18 and 2C19. Evidence that this drug is a mechanism-based inhibitor specific for cytochrome P-450 2C9. European Journal of Biochemistry / Febs. 241: 797-804. PMID 8944768 DOI: 10.1111/J.1432-1033.1996.00797.X  1
1996 Renaud JP, Davydov DR, Heirwegh KPM, Mansuy D, Hui Bon Hoa G. Thermodynamic studies of substrate binding and spin transitions in human cytochrome P-450 3A4 expressed in yeast microsomes Biochemical Journal. 319: 675-681. PMID 8920966  1
1996 Quilez R, De Lauzon S, Desfosses B, Mansuy D, Mahy JP. Artificial peroxidase-like hemoproteins based on antibodies constructed from a specifically designed ortho-carboxy substituted tetraarylporphyrin hapten and exhibiting a high affinity for iron-porphyrins Febs Letters. 395: 73-76. PMID 8849692 DOI: 10.1016/0014-5793(96)01006-X  1
1996 Robin MA, Maratrat M, Le Roy M, Le Breton FP, Bonierbale E, Dansette P, Ballet F, Mansuy D, Pessayre D. Antigenic targets in tienilic acid hepatitis: Both cytochrome P450 2C11 and 2C11-tienilic acid adducts are transported to the plasma membrane of rat hepatocytes and recognized by human sera Journal of Clinical Investigation. 98: 1471-1480. PMID 8823314 DOI: 10.1172/Jci118936  1
1996 Mansuy D, Dansette PM. New biological reactive intermediates: Metabolic activation of thiophene derivatives Advances in Experimental Medicine and Biology. 387: 1-6. PMID 8794187  1
1996 Gaspard S, Chottard G, Mahy JP, Mansuy D. Study of the coordination chemistry of prostaglandin G/H synthase by resonance Raman spectroscopy European Journal of Biochemistry. 238: 529-537. PMID 8681968  1
1996 Sari MA, Booker S, Jaouen M, Vadon S, Boucher JI, Pompon D, Mansuy D. Expression in yeast and purification of functional macrophage nitric oxide synthase. Evidence for cysteine-194 as iron proximal ligand. Biochemistry. 35: 7204-13. PMID 8679549 DOI: 10.1021/Bi960087U  1
1996 Lesuisse D, Gourvest JF, Benslimane O, Canu F, Delaisi C, Doucet B, Hartmann C, Lefrançois JM, Tric B, Mansuy D, Philibert D, Teutsch G. Structure-activity relationships of a new family of steroidal aromatase inhibitors. 1. Synthesis and evaluation of a series of analogs related to 19-[(methylthio)methyl]androstenedione (RU54115) Journal of Medicinal Chemistry. 39: 757-772. PMID 8576919 DOI: 10.1021/Jm950539L  1
1996 Pons C, Dansette PM, Gregeois J, Homberg JC, Billett EE, Mansuy D. Human anti-mitochondria autoantibodies appearing in iproniazid-induced immunoallergic hepatitis recognize human liver monoamine oxidase B Biochemical and Biophysical Research Communications. 218: 118-124. PMID 8573115 DOI: 10.1006/Bbrc.1996.0021  1
1996 Vadon S, Custot J, Boucher JL, Mansuy D. Synthesis and effects on arginase and nitric oxide synthase of two novel analogues of Nω-hydroxyarginine, Nω-hydroxyindospicine and p-hydroxyamidinophenylalanine Journal of the Chemical Society - Perkin Transactions 1. 645-648. DOI: 10.1039/P19960000645  1
1996 Battioni P, Cardin E, Louloudi M, Schöllhorn B, Spyroulias GA, Mansuy D, Traylor TG. Metalloporphyrinosilicas: A new class of hybrid organic-inorganic materials acting as selective biomimetic oxidation catalysts Chemical Communications. 2037-2038. DOI: 10.1039/Cc9960002037  1
1996 Maldotti A, Bartocci C, Varani G, Molinari A, Battioni P, Mansuy D. Oxidation of Cyclohexane by Molecular Oxygen Photoassisted by meso-Tetraarylporphyrin Iron(III)-Hydroxo Complexes Inorganic Chemistry. 35: 1126-1131. DOI: 10.1021/Ic950386S  1
1996 Maldotti A, Molinari A, Argazzi R, Amadelli R, Battioni P, Mansuy D. Redox properties of photoexcited (nBu4N)3 PW12O40/FE(III) porphyrins composite systems Journal of Molecular Catalysis a: Chemical. 114: 141-150. DOI: 10.1016/S1381-1169(96)00312-3  1
1996 Martinez-Lorente MA, Battioni P, Kleemiss W, Bartoli JF, Mansuy D. Manganese porphyrins covalently bound to silica and montmorillonite K10 as efficient catalysts for alkene and alkane oxidation by hydrogen peroxide Journal of Molecular Catalysis a: Chemical. 113: 343-353. DOI: 10.1016/S1381-1169(96)00109-4  1
1996 Maldotti A, Molinari A, Bergamini P, Amadelli R, Battioni P, Mansuy D. Photocatalytic oxidation of cyclohexane by (nBu4N)4W10O32/Fe(III) porphyrins integrated systems Journal of Molecular Catalysis a: Chemical. 113: 147-157. DOI: 10.1016/S1381-1169(96)00107-0  1
1996 Iwanejko R, Battioni P, Mansuy D, Mlodnicka T. Reactivity of polyhalogenated metalloporphyrins in epoxidation of propene with magnesium monoperoxyphthalate Journal of Molecular Catalysis a: Chemical. 111: 7-9. DOI: 10.1016/1381-1169(96)00186-0  1
1996 Battioni P, Iwanejko R, Mansuy D, Mlodnicka T, Poltowicz J, Sanchez F. Reactivity of polyhalogenated and zeolite-encapsulated metalloporphyrins in oxidation with dioxygen Journal of Molecular Catalysis a: Chemical. 109: 91-98. DOI: 10.1016/1381-1169(96)00020-9  1
1996 Boucher JL, Vadon S, Tomas A, Viossat B, Mansuy D. Oxidation of arylamidoximes by hydrogen peroxide and horseradish peroxidase in water: Easy preparation and X-ray structure of O-(arylimidoyl)arylamidoximes Tetrahedron Letters. 37: 3113-3116. DOI: 10.1016/0040-4039(96)00504-7  1
1996 Custot J, Boucher JL, Vadon S, Guedes C, Dijols S, Delaforge M, Mansuy D. Nω-hydroxyamino-α-amino acids as a new class of very strong inhibitors of arginases Journal of Biological Inorganic Chemistry. 1: 73-82. DOI: 10.1007/S007750050025  1
1996 Policar C, Artaud I, Mansuy D. First Synthesis of a Binuclear [MnII(bipy)-FeIII(porphyrin)] Complex: Spectroscopic Characterization and First Evidence of Reversible Formation of Manganese(III) as Manganese Peroxidase Inorganic Chemistry. 35: 210-216.  1
1996 Bouy-Debec D, Brigaud O, Leduc P, Battioni P, Mansuy D. Synthesis of new iron polyfluorinated porphyrins derived from meso-tetrapentafluorophenylporphyrin and their catalytic properties for alkane hydroxylation Gazzetta Chimica Italiana. 126: 233-237.  1
1995 Mansuy D, Boucher JL, Clement B. On the mechanism of nitric oxide formation upon oxidative cleavage of CN(OH) bonds by NO-synthases and cytochromes P450 Biochimie. 77: 661-667. PMID 8589076 DOI: 10.1016/0300-9084(96)88181-8  1
1995 Mansuy D. Cytochromes P450 and drug toxicity - Immunological consequences Clinical Reviews in Allergy and Immunology. 13: 201-209. PMID 8535927 DOI: 10.1007/BF02771761  1
1995 Bensoussan C, Delaforge M, Mansuy D. Particular ability of cytochromes P450 3A to form inhibitory P450-iron-metabolite complexes upon metabolic oxidation of aminodrugs Biochemical Pharmacology. 49: 591-602. PMID 7887973 DOI: 10.1016/0006-2952(94)00477-4  1
1995 Mancy A, Broto P, Dijols S, Dansette PM, Mansuy D. The substrate binding site of human liver cytochrome P450 2C9: An approach using designed tienilic acid derivatives and molecular modeling Biochemistry. 34: 10365-10375. PMID 7654690 DOI: 10.1021/Bi00033A007  1
1995 Sedqi M, Delaforge M, Mansuy D, Martin B, Jollès P, Migliore-Samour D. Immunostimulating lipopeptide, LtriP (RP 56142): Comparison of the effect on hepatic cytochrome P 450 modulation and radioprotection in male and female of three mouse strains Experientia. 51: 790-798. PMID 7649238 DOI: 10.1007/BF01922432  1
1995 Tomasi I, Artaud I, Bertheau Y, Mansuy D. Metabolism of polychlorinated phenols by Pseudomonas cepacia AC1100: Determination of the first two steps and specific inhibitory effect of methimazole Journal of Bacteriology. 177: 307-311. PMID 7529225  1
1995 Pouzet P, Erdelmeier I, Ginderow D, Mornon JP, Dansette P, Mansuy D. Thiophene S-oxides: Convenient preparation, first complete structural characterization and unexpected dimerization of one of them, 2,5-diphenylthiophene-1-oxide Journal of the Chemical Society, Chemical Communications. 473-474. DOI: 10.1039/C39950000473  1
1995 Tommasi L, Shechter-Barloy L, Varech D, Battioni JP, Donnadieu B, Verelst M, Bousseksou A, Mansuy D, Tuchagues JP. Synthesis of pyrroloquinolinequinone analogs. Molecular structure and Mössbauer and magnetic properties of their iron complexes Inorganic Chemistry. 34: 1514-1523. DOI: 10.1021/Ic00110A033  1
1995 Deniaud D, Schöllorn B, Mansuy D, Rouxel J, Battioni P, Bujoli B. Synthesis and catalytic properties of manganese porphyrins incorporated into phosphonate networks Chemistry of Materials. 7: 995-1000. DOI: 10.1021/Cm00053A028  1
1995 Mansuy D. Cytochromes P450 and drug toxicity: immunological consequences | Cytochromes P450 et toxicité médicamenteuse : conséquences immunologiques Revue Francaise D'Allergologie Et D'Immunologie Clinique. 35: 470-475. DOI: 10.1016/S0335-7457(05)80533-7  1
1995 Jousserandot A, Boucher JL, Desseaux C, Delaforge M, Mansuy D. Formation of nitrogen oxides including NO from oxidative cleavage of CN(OH) bonds: A general cytochrome P450-dependent reaction Bioorganic and Medicinal Chemistry Letters. 5: 423-426. DOI: 10.1016/0960-894X(95)00048-X  1
1995 Sennequier N, Boucher JL, Battioni P, Mansuy D. Superoxide anion efficiently performs the oxidative cleavage of CNOH bonds of amidoximes and N-hydroxyguanidines with formation of nitrogen oxides Tetrahedron Letters. 36: 6059-6062. DOI: 10.1016/0040-4039(95)01242-A  1
1995 Artaud I, Tomasi I, Martin G, Petre D, Mansuy D. First direct aromatic ring cleavage of phenols related to vanillin into muconic acid derivatives catalyzed by a microorganism Tetrahedron Letters. 36: 869-872. DOI: 10.1016/0040-4039(94)02382-L  1
1994 López-Garcia MP, Dansette PM, Mansuy D. Thiophene derivatives as new mechanism-based inhibitors of cytochromes P-450: Inactivation of yeast-expressed human liver cytochrome P-450 2C9 by tienilic acid Biochemistry. 33: 166-175. PMID 8286335 DOI: 10.1021/Bi00167A022  1
1994 Lecoeur S, Bonierbale E, Challine D, Gautier JC, Valadon P, Dansette PM, Catinot R, Ballet F, Mansuy D, Beaune PH. Specificity of in vitro covalent binding of tienilic acid metabolites to human liver microsomes in relationship to the type of hepatotoxicity: Comparison with two directly hepatotoxic drugs Chemical Research in Toxicology. 7: 434-442. PMID 8075377 DOI: 10.1021/Tx00039A023  1
1994 Peyronneau MA, Delaforge M, Riviere R, Renaud JP, Mansuy D. High affinity of ergopeptides for cytochromes P450 3A. Importance of their peptide moiety for P450 recognition and hydroxylation of bromocriptine European Journal of Biochemistry. 223: 947-956. PMID 8055971 DOI: 10.1111/j.1432-1033.1994.tb19072.x  1
1994 Boucher JL, Delaforge M, Mansuy D. Dehydration of alkyl- and arylaldoximes as a new cytochrome P450- catalyzed reaction: Mechanism and stereochemical characteristics Biochemistry. 33: 7811-7818. PMID 8011645 DOI: 10.1021/Bi00191A008  1
1994 Mahy JP, Gaspard S, Delaforge M, Mansuy D. Reactions of prostaglandin H synthase with monosubstituted hydrazines and diazenes. Formation of iron(II)-diazene and iron(III)-σ-alkyl or iron(III)-σ-aryl complexes European Journal of Biochemistry. 226: 445-457. PMID 8001562 DOI: 10.1111/j.1432-1033.1994.tb20069.x  1
1994 Boucher JL, Custot J, Vadon S, Delaforge M, Lepoivre M, Tenu JP, Yapo A, Mansuy D. N(ω)-Hydroxy-L-arginine, an intermediate in the L-arginine to nitric oxide pathway, is a strong inhibitor of live and macrophage arginase Biochemical and Biophysical Research Communications. 203: 1614-1621. PMID 7945311 DOI: 10.1006/bbrc.1994.2371  1
1994 Beaune P, Pessayre D, Dansette P, Mansuy D, Manns M. Autoantibodies against cytochromes P450: role in human diseases Advances in Pharmacology (San Diego, Calif.). 30: 199-245. PMID 7833293 DOI: 10.1016/S1054-3589(08)60175-1  1
1994 Thellend A, Battioni P, Mansuy D. Ammonium acetate as a very simple and efficient cocatalyst for manganese porphyrin-catalysed oxygenation of hydrocarbons by hydrogen peroxide Journal of the Chemical Society, Chemical Communications. 1035-1036. DOI: 10.1039/C39940001035  1
1994 Bartoli JF, Battioni P, De Foor WR, Mansuy D. Synthesis and remarkable properties of iron β-polynitroporphyrins as catalysts for monooxygenation reactions Journal of the Chemical Society, Chemical Communications. 23-24. DOI: 10.1039/C39940000023  1
1994 Battioni P, Iwanejkob R, Mansuy D, Mlodnicka T. Oxidation of Cyclohexane Catalyzed by Polyhalogenated and Perhalogenated Manganese Porphyrins Studies in Surface Science and Catalysis. 82: 653-658. DOI: 10.1016/S0167-2991(08)63460-6  1
1993 Mazouz F, Gueddari S, Burstein C, Mansuy D, Milcent R. 5-[4-(Benzyloxy)phenyl]-1,3,4-oxadiazol-2(3H)-one derivatives and related analogues: New reversible, highly potent, and selective monoamine oxidase type B inhibitors Journal of Medicinal Chemistry. 36: 1157-1167. PMID 8487255 DOI: 10.1021/Jm00061A006  1
1993 Croke DT, Perrouault L, Sari MA, Battioni JP, Mansuy D, Helene C, Le Doan T. Structure-activity relationships for DNA photocleavage by cationic porphyrins. Journal of Photochemistry and Photobiology. B, Biology. 18: 41-50. PMID 8487125 DOI: 10.1016/1011-1344(93)80039-C  0.6
1993 Atta M, Lamarche N, Battioni JP, Massie B, Langelier Y, Mansuy D, Fontecave M. Escherichia coli and herpes-simplex-virus ribonucleotide reductase R2 subunit. Compared reactivities of the redox centres. The Biochemical Journal. 290: 807-10. PMID 8384445 DOI: 10.1042/Bj2900807  0.44
1993 Peyronneau MA, Renaud JP, Urban P, Cullin C, Pompon D, Mansuy D, Jaouen M. Expression in yeast of three allelic cDNAs coding for human liver P-450 3A4. Different stabilities, binding properties and catalytic activities of the yeast-produced enzymes European Journal of Biochemistry. 218: 355-361. PMID 8269924 DOI: 10.1111/j.1432-1033.1993.tb18384.x  1
1993 Renaud JP, Peyronneau MA, Urban P, Truan G, Cullin C, Pompon D, Beaune P, Mansuy D. Recombinant yeast in drug metabolism Toxicology. 82: 39-52. PMID 8236280 DOI: 10.1016/0300-483X(93)90058-Z  1
1993 Renaud JP, Boucher JL, Vadon S, Delaforge M, Mansuy D. Particular ability of liver P450s3A to catalyze the oxidation of N omega-hydroxyarginine to citrulline and nitrogen oxides and occurrence in no synthases of a sequence very similar to the heme-binding sequence in P450s. Biochemical and Biophysical Research Communications. 192: 53-60. PMID 7682811 DOI: 10.1006/bbrc.1993.1380  0.44
1993 Artaud I, Ben-Aziza K, Mansuy D. Iron porphyrin-catalyzed oxidation of 1,2-dimethoxyarenes: A discussion of the different reactions involved and the competition between the formation of methoxyquinones or muconic dimethyl esters Journal of Organic Chemistry. 58: 3373-3380. DOI: 10.1021/Jo00064A026  1
1992 Dansette PM, Thang DC, el Amri H, Mansuy D. Evidence for thiophene-S-oxide as a primary reactive metabolite of thiophene in vivo: formation of a dihydrothiophene sulfoxide mercapturic acid. Biochemical and Biophysical Research Communications. 186: 1624-30. PMID 1510686 DOI: 10.1016/S0006-291X(05)81594-3  0.32
1992 Martinat C, Amar C, Dansette PM, Leclaire J, Lopez-Garcia P, Cao TD, N'Guyen HN, Mansuy D. In vitro metabolism of isaxonine phosphate: formation of two metabolites, 5-hydroxyisaxonine and 2-aminopyrimidine, and covalent binding to microsomal proteins. European Journal of Pharmacology. 228: 63-71. PMID 1397069 DOI: 10.1016/0926-6917(92)90013-3  1
1992 Battioni P, Bartoli JF, Mansuy D, Byun YS, Traylor TG. An easy access to polyhalogenated metalloporphyrins covalently bound to polymeric supports as efficient catalysts for hydrocarbon oxidation Journal of the Chemical Society, Chemical Communications. 1051-1053. DOI: 10.1039/C39920001051  1
1991 Battioni JP, Fontecave M, Jaouen M, Mansuy D. Vitamin E derivatives as new potent inhibitors of microsomal lipid peroxidation. Biochemical and Biophysical Research Communications. 174: 1103-8. PMID 1996979 DOI: 10.1016/0006-291X(91)91534-J  0.56
1991 Maldotti A, Bartocci C, Amadelli R, Polo E, Battioni P, Mansuy D. Oxidation of alkanes by dioxygen catalysed by photoactivated iron porphyrins Journal of the Chemical Society, Chemical Communications. 1487-1489. DOI: 10.1039/C39910001487  0.56
1991 Bartoli JF, Brigaud O, Battioni P, Mansuy D. Hydroxylation of linear alkanes catalysed by iron porphyrins: particular efficacy and regioselectivity of perhalogenated porphyrins Journal of the Chemical Society, Chemical Communications. 440-442. DOI: 10.1039/C39910000440  0.56
1991 Traylor TG, Byun YS, Traylor PS, Battioni P, Mansuy D. Polymeric polyhalogeneted metallopophyrin catalysts for hydroxylation of alkanes and epoxidation of alkenes Journal of the American Chemical Society. 113: 7821-7823. DOI: 10.1021/Ja00020A087  1
1991 Battioni P, Brigaud O, Desvaux H, Mansuy D, Traylor TG. Preparation of functionalized polyhalogenated tetraaryl-porphyrins by selective substitution of the p-Fluorines of meso-tetra-(pentafluorophenyl)porphyrins Tetrahedron Letters. 32: 2893-2896. DOI: 10.1016/0040-4039(91)80641-I  1
1990 Sari MA, Battioni JP, Dupré D, Mansuy D, Le Pecq JB. Interaction of cationic porphyrins with DNA: importance of the number and position of the charges and minimum structural requirements for intercalation. Biochemistry. 29: 4205-15. PMID 2361139 DOI: 10.1021/bi00469a025  0.6
1990 Neau E, Dansette PM, Andronik V, Mansuy D. Hydroxylation of the thiophene ring by hepatic monooxygenases. Evidence for 5-hydroxylation of 2-aroylthiophenes as a general metabolic pathway using a simple UV-visible assay. Biochemical Pharmacology. 39: 1101-7. PMID 2322296 DOI: 10.1016/0006-2952(90)90290-2  0.52
1990 Dansette PM, Amar C, Smith C, Pons C, Mansuy D. Oxidative activation of the thiophene ring by hepatic enzymes. Hydroxylation and formation of electrophilic metabolites during metabolism of tienilic acid and its isomer by rat liver microsomes. Biochemical Pharmacology. 39: 911-8. PMID 2310416 DOI: 10.1016/0006-2952(90)90207-2  0.32
1990 Dansette PM, Sassi A, Deschamps C, Mansuy D. Sulfur containing compounds as antioxidants Advances in Experimental Medicine and Biology. 264: 209-215. PMID 2244498 DOI: 10.1007/978-1-4684-5730-8_34  1
1990 Fontecave M, Jaouen M, Mansuy D, Costa D, Zalma R, Pezerat H. Microsomal lipid peroxidation and oxy-radicals formation are induced by insoluble iron-containing minerals. Biochemical and Biophysical Research Communications. 173: 912-8. PMID 2176494 DOI: 10.1016/S0006-291X(05)80872-1  0.56
1990 Michaud-Soret I, Daniel R, Chopard C, Mansuy D, Cucurou C, Ullrich V, Chottard JC. Soybean lipoxygenases-1, -2a, -2b and -2c do not contain PQQ. Biochemical and Biophysical Research Communications. 172: 1122-8. PMID 2173916 DOI: 10.1016/0006-291X(90)91563-8  0.36
1990 Fontecave M, Gerez C, Mansuy D, Reichard P. Reduction of the Fe(III)-tyrosyl radical center of escherichia coli ribonucleotide reductase by dithiothreitol Journal of Biological Chemistry. 265: 10919-10924. PMID 2113527  1
1990 Boutorine AS, Le Doan T, Battioni JP, Mansuy D, Dupré D, Hélène C. Rapid routes of synthesis of chemically reactive and highly radioactively labeled alpha- and beta-oligonucleotide derivatives for in vivo studies. Bioconjugate Chemistry. 1: 350-6. PMID 1965883 DOI: 10.1021/Bc00005A009  1
1990 Barloy L, Battioni P, Mansuy D. Manganese porphyrins supported on montmorillonite as hydrocarbon mono-oxygenation catalysts: particular efficacy for linear alkane hydroxylation Journal of the Chemical Society, Chemical Communications. 1365-1367. DOI: 10.1039/C39900001365  0.56
1989 Battioni P, Lallier J, Barloy L, Mansuy D. Mono-oxygenase-like oxidation of hydrocarbons using supported manganese–porpnyrin catalysts: beneficial effects of a silica support for alkane hydroxylation Journal of the Chemical Society, Chemical Communications. 1149-1151. DOI: 10.1039/C39890001149  0.56
1989 Bartocci C, Maldotti A, Varani G, Carassiti V, Battioni P, Mansuy D. Iron meso-tetra(2,6-dichlorophenyl)porphyrin as a very efficient catalyst for the photoreduction of carbon tetrachloride by alcohols Journal of the Chemical Society, Chemical Communications. 964-965. DOI: 10.1039/C39890000964  1
1988 Sari MA, Battioni JP, Dupre D, Mansuy D, Le Pecq JB. Cationic porphyrin-DNA interactions: importance of the number and position of the charges. Biochemical Pharmacology. 37: 1861-2. PMID 3377854 DOI: 10.1016/0006-2952(88)90483-2  0.6
1988 Mahy JP, Bedi G, Battioni P, Mansuy D. Aziridination of alkenes catalysed by porphyrinirons: Selection of catalysts for optimal efficiency and stereospecificity Journal of the Chemical Society, Perkin Transactions 2. 1517-1524. DOI: 10.1039/P29880001517  1
1988 Mahy JP, Bedi G, Battioni P, Mansuy D. Allylic amination of alkenes by tosyliminoiodobenzene: manganese porphyrins as suitable catalysts Tetrahedron Letters. 29: 1927-1930. DOI: 10.1016/S0040-4039(00)82081-X  1
1987 Beaune P, Dansette PM, Mansuy D, Kiffel L, Finck M, Amar C, Leroux JP, Homberg JC. Human anti-endoplasmic reticulum autoantibodies appearing in a drug-induced hepatitis are directed against a human liver cytochrome P-450 that hydroxylates the drug. Proceedings of the National Academy of Sciences of the United States of America. 84: 551-5. PMID 3540968 DOI: 10.1073/Pnas.84.2.551  1
1987 Fontecave M, Mansuy D, Jaouen M, Pezerat H. The stimulatory effects of asbestos on NADPH-dependent lipid peroxidation in rat liver microsomes. The Biochemical Journal. 241: 561-5. PMID 3036068 DOI: 10.1042/Bj2410561  0.56
1987 Battioni P, Bartoli JF, Leduc P, Fontecave M, Mansuy D. A new and efficient biomimetic system for hydrocarbon oxidation by dioxygen using manganese porphyrins, imidazole, and zinc Journal of the Chemical Society, Chemical Communications. 791-792. DOI: 10.1039/C39870000791  0.56
1987 Schauer CK, Anderson OP, Lavallee DK, Battioni JP, Mansuy D. The chemistry of N-alkylporphyrin complexes: A comparison of reactivities and structures of chlorozinc(II) complexes of N-benzyl-, N-methyl-, and N-phenyltetraphenylporphyrin Journal of the American Chemical Society. 109: 3922-3928. DOI: 10.1021/Ja00247A016  1
1986 Mansuy D, Sassi A, Dansette PM, Plat M. A new potent inhibitor of lipid peroxidation in vitro and in vivo, the hepatoprotective drug anisyldithiolthione Biochemical and Biophysical Research Communications. 135: 1015-1021. PMID 3964266 DOI: 10.1016/0006-291X(86)91029-6  1
1986 Battioni P, Renaud J, Bartoli JF, Mansuy D. Hydroxylation of alkanes by hydrogen peroxide: and efficient system using manganese porphyrins and imidazole as catalysts Journal of the Chemical Society, Chemical Communications. 341-343. DOI: 10.1039/C39860000341  0.56
1985 Renaud J, Battioni P, Bartoli JF, Mansuy D. A very efficient system for alkene epoxidation by hydrogen peroxide: catalysis by manganese-porphyrins in the presence of imidazole Journal of the Chemical Society, Chemical Communications. 888-889. DOI: 10.1039/C39850000888  0.56
1985 Mansuy D, Battioni P, Renaud J-, Guerin P. Asymmetric epoxidation of alkenes catalysed by a basket-handlë iron-porphyrin bearing amino acids Journal of the Chemical Society, Chemical Communications. 155-156. DOI: 10.1039/C39850000155  0.56
1984 Mansuy D, Dansette PM, Foures C, Jaouen M, Moinet G, Bayer N. Metabolic hydroxylation of the thiophene ring: isolation of 5-hydroxy-tienilic acid as the major urinary metabolite of tienilic acid in man and rat. Biochemical Pharmacology. 33: 1429-35. PMID 6732860 DOI: 10.1016/0006-2952(84)90409-X  1
1984 Mansuy D, Leclaire J, Fontecave M, Momenteau M. Oxidation of monosubstituted olefins by cytochromes P-450 and heme models: evidence for the formation of aldehydes in addition to epoxides and allylic alcohols. Biochemical and Biophysical Research Communications. 119: 319-25. PMID 6704124 DOI: 10.1016/0006-291X(84)91654-1  0.44
1984 Mansuy D, Battioni P, Renaud J. In the presence of imidazole, iron-and manganese-porphyrins catalyse the epoxidation of alkenes by alkyl hydroperoxides Journal of the Chemical Society, Chemical Communications. 1255-1257. DOI: 10.1039/C39840001255  0.56
1984 Mansuy D, Mahy J, Dureault A, Bedi G, Battioni P. Iron- and manganese-porphyrin catalysed aziridination of alkenes by tosyl- and acyl-iminoiodobenzene Journal of the Chemical Society, Chemical Communications. 1161-1163. DOI: 10.1039/C39840001161  0.56
1984 Fontecave M, Mansuy D. Alkene epoxidation by iodosylbenzene catalysed by porphyrin and non-porphyrin iron complexes: the importance of the porphyrin ligand in cytochrome P-450 and Heme model reactions Journal of the Chemical Society, Chemical Communications. 879-881. DOI: 10.1039/C39840000879  0.44
1983 Mansuy D, Fontecave M. Reduction of benzyl halides by liver microsomes. Formation of 478 NM-absorbing sigma-alkyl-ferric cytochrome P-450 complexes. Biochemical Pharmacology. 32: 1871-9. PMID 6882464 DOI: 10.1016/0006-2952(83)90052-7  0.44
1983 Mansuy D, Fontecave M, Bartoli J. Mono-oxigenase-like dioxygen activation leading to alkane hydroxylation and olefin epoxidation by an MnIII(porphyrin)–ascorbate biphasic system Journal of the Chemical Society, Chemical Communications. 253-254. DOI: 10.1039/C39830000253  0.44
1982 Mansuy D, Fontecave M. A heme model system for the reduction of substrates by microsomal cytochrome P 450. Biochemical and Biophysical Research Communications. 104: 1651-7. PMID 7073760 DOI: 10.1016/0006-291X(82)91443-7  0.44
1982 Mansuy D, Fontecave M, Battioni J. Intermediate formation of a σ-alkyl iron(III) complex in the reduction of 4-nitrobenzyl chloride catalysed by iron(II)-prophyrins Journal of the Chemical Society, Chemical Communications. 317-319. DOI: 10.1039/C39820000317  0.44
1981 Mansuy D, Dansette PM, Pecquet F, Chottard JC. Iron-porphyrin catalysis of the oxidative dealkylation of para-nitro-anisole and 7-ethoxycoumarin by cumylhydroperoxide: a possible model for the corresponding cytochrome P 450-dependent reactions. Biochemical and Biophysical Research Communications. 96: 433-9. PMID 7437045 DOI: 10.1016/0006-291X(80)91233-4  0.36
1981 Stetzkowski F, Banerjee R, Lallemand JY, Cendrier B, Mansuy D. 13C nuclear magnetic resonance studies of the binding of alkyl isocyanides to soybean leghemoglobin; comparison with animal myoglobins. Biochimie. 62: 795-801. PMID 7193485 DOI: 10.1016/S0300-9084(80)80135-0  0.68
1981 Lange M, Battioni JP, Mansuy D, Lexa D, Saveant JM. Comparison of u.v.–visible spectra of iron(I)–porphyrin– and iron(II)–porphyrin (thiolato)-(thiocarbonyl) and -(carbene) complexes. Relevance to ferrous cytochrome P450 complexes Journal of the Chemical Society, Chemical Communications. 888-890. DOI: 10.1039/C39810000888  0.36
1980 Mansuy D, Fontecave M, Chottard JC. A heme model study of carbon tetrachloride metabolism: mechanisms of phosgene and carbon dioxide formation. Biochemical and Biophysical Research Communications. 95: 1536-42. PMID 6774725 DOI: 10.1016/S0006-291X(80)80072-6  0.44
1980 Gans P, Regnard JR, Battioni P, Mansuy D. Mössbauer study of (2-nitrisopropane)(n-methylimidazole) and (2-nitrosopropane)(isoropylamie) iron(II) tetraphenylporphyrins Chemical Physics. 45: 401-408. DOI: 10.1016/0301-0104(80)87008-X  1
1978 Mansuy D, Thillet J, Cendrier B, Lallemand JY, Chottard JC. Carbon-13 NMR studies of C2H5N13C bound to hemoproteins - evidence for a different distal proteic environment in beta-chains either isolated or within human hemoglobin. Biochemical and Biophysical Research Communications. 83: 217-25. PMID 697811 DOI: 10.1016/0006-291X(78)90419-9  0.48
1978 Mansuy D, Rouer E, Bacot C, Gans P, Chottard JC, Leroux JP. Interaction of aliphatic N-hydroxylamines with microsomal cytochrome P450: nature of the different derived complexes and inhibitory effects on monoxygenases activities. Biochemical Pharmacology. 27: 1129-37. PMID 29646 DOI: 10.1016/0006-2952(78)90456-2  0.32
1978 Mansuy D, Beaune P, Cresteil T, Bacot C, Chottard JC, Gans P. Formation of complexes between microsomal cytochrome P-450-Fe(II) and nitrosoarenes obtained by oxidation of arylhydroxylamines or reduction of nitroarenes in situ. European Journal of Biochemistry / Febs. 86: 573-9. PMID 26570 DOI: 10.1111/J.1432-1033.1978.Tb12341.X  0.32
1977 Mansuy D, Gans P, Chottard JC, Bartoli JF. Nitrosoalkanes as Fe(II) ligands in the 455-nm-absorbing cytochrome P-450 complexes formed from nitroalkanes in reducing conditions. European Journal of Biochemistry / Febs. 76: 607-15. PMID 891529 DOI: 10.1111/J.1432-1033.1977.Tb11631.X  1
1976 Mansuy D, Lallemand JY, Chottard JC, Cendrier B. Carbon-13 NMR studies of C2H5N13C binding to various hemoproteins. Biochemical and Biophysical Research Communications. 70: 595-9. PMID 945739 DOI: 10.1016/0006-291X(76)91089-5  0.56
1976 Mansuy D, Beaune P, Chottard JC, Bartoli JF, Gans P. The nature of the "455 nm absorbing complex" formed during the cytochrome P450 dependent oxidative metabolism of amphetamine. Biochemical Pharmacology. 25: 609-12. PMID 942497 DOI: 10.1016/0006-2952(76)90398-1  0.32
1975 Mansuy D, Nastainczyk W, Ullrich V. The mechanism of halothane binding to microsomal cytochrome P450. Naunyn-Schmiedeberg's Archives of Pharmacology. 285: 315-24. PMID 4280521 DOI: 10.1007/BF00501461  0.44
1975 Mansuy D, Duppel W, Ruf HH, Ullrich V. Phosphines as ligands to microsomal cytochrome P-450. Hoppe-Seyler's Zeitschrift Fur Physiologische Chemie. 355: 1341-9. PMID 4156679 DOI: 10.1515/Bchm2.1974.355.2.1341  0.36
1974 Chottard JC, Mulliez E, Girault JP, Mansuy D. trans-Bonding bidentate macroligands in platinum(II) complexes Journal of the Chemical Society, Chemical Communications. DOI: 10.1039/C3974000780A  0.44
1972 Mansuy D, Julia M. Radikalische Cyclisierungen 15. Mitt. Oxidative Cyclisierung Von Cis- Und Trans-2,6-Dimethyl-9-Phenyl-Nonadien-(2,6) Mit Dibenzoylperoxid Cheminform. 3. DOI: 10.1002/Chin.197248204  0.44
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