Todd K. Hyster - Publications

Affiliations: 
Princeton University, Princeton, NJ 

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Liu Y, Bender SG, Sorigue D, Diaz DJ, Ellington AD, Mann G, Allmendinger S, Hyster TK. Asymmetric Synthesis of α-Chloroamides via Photoenzymatic Hydroalkylation of Olefins. Journal of the American Chemical Society. PMID 38442365 DOI: 10.1021/jacs.4c00927  0.335
2023 Clements HD, Flynn AR, Nicholls BT, Grosheva D, Lefave SJ, Merriman MT, Hyster TK, Sigman MS. Using Data Science for Mechanistic Insights and Selectivity Predictions in a Non-Natural Biocatalytic Reaction. Journal of the American Chemical Society. PMID 37530568 DOI: 10.1021/jacs.3c03639  0.302
2023 Ouyang Y, Turek-Herman J, Qiao T, Hyster TK. Asymmetric Carbohydroxylation of Alkenes Using Photoenzymatic Catalysis. Journal of the American Chemical Society. PMID 37498747 DOI: 10.1021/jacs.3c06618  0.437
2023 Li X, Page CG, Zanetti-Polzi L, Kalra AP, Oblinsky DG, Daidone I, Hyster TK, Scholes GD. Mechanism and Dynamics of Photodecarboxylation Catalyzed by Lactate Monooxygenase. Journal of the American Chemical Society. 145: 13232-13240. PMID 37289179 DOI: 10.1021/jacs.3c02446  0.35
2023 Page CG, Cao J, Oblinsky DG, MacMillan SN, Dahagam S, Lloyd RM, Charnock SJ, Scholes GD, Hyster TK. Regioselective Radical Alkylation of Arenes Using Evolved Photoenzymes. Journal of the American Chemical Society. PMID 37199445 DOI: 10.1021/jacs.3c03607  0.416
2023 Hyster T, Page C, Cao J, Oblinsky D, MacMillan S, Dahagam S, Lloyd R, Charnock S, Scholes G. Regioselective Radical Alkylation of Arenes Using Evolved Photoenzymes. Research Square. PMID 36865242 DOI: 10.21203/rs.3.rs-2602958/v1  0.428
2023 Fu H, Qiao T, Carceller JM, MacMillan SN, Hyster TK. Asymmetric -Alkylation of Nitroalkanes Enzymatic Photoredox Catalysis. Journal of the American Chemical Society. 145: 787-793. PMID 36608280 DOI: 10.1021/jacs.2c12197  0.434
2022 Nicholls BT, Qiao T, Hyster TK. A Photoenzyme for Challenging Lactam Radical Cyclizations. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 33: 1204-1208. PMID 37876576  0.366
2022 Laguerre N, Riehl PS, Oblinsky DG, Emmanuel MA, Black MJ, Scholes GD, Hyster TK. Radical Termination via β-Scission Enables Photoenzymatic Allylic Alkylation Using "Ene"-Reductases. Acs Catalysis. 12: 9801-9805. PMID 37859751 DOI: 10.1021/acscatal.2c02294  0.339
2022 Ye Y, Cao J, Oblinsky DG, Verma D, Prier CK, Scholes GD, Hyster TK. Using enzymes to tame nitrogen-centred radicals for enantioselective hydroamination. Nature Chemistry. PMID 36376390 DOI: 10.1038/s41557-022-01083-z  0.425
2022 Fu H, Cao J, Qiao T, Qi Y, Charnock SJ, Garfinkle S, Hyster TK. An Asymmetric sp-sp Cross-Electrophile Coupling Using 'Ene'-Reductases. Nature. PMID 35952713 DOI: 10.1038/s41586-022-05167-1  0.438
2021 Gao X, Turek-Herman JR, Choi YJ, Cohen RD, Hyster TK. Photoenzymatic Synthesis of α-Tertiary Amines by Engineered Flavin-Dependent "Ene"-Reductases. Journal of the American Chemical Society. PMID 34784482 DOI: 10.1021/jacs.1c09828  0.372
2021 Fu H, Lam H, Emmanuel MA, Kim JH, Sandoval BA, Hyster TK. Ground-State Electron Transfer as an Initiation Mechanism for Biocatalytic C-C Bond Forming Reactions. Journal of the American Chemical Society. PMID 34114803 DOI: 10.1021/jacs.1c04334  0.423
2021 Ye Y, Fu H, Hyster TK. Activation modes in biocatalytic radical cyclization reactions. Journal of Industrial Microbiology & Biotechnology. PMID 33674826 DOI: 10.1093/jimb/kuab021  0.33
2020 Page CG, Cooper SJ, DeHovitz JS, Oblinsky DG, Biegasiewicz KF, Antropow AH, Armbrust KW, Ellis JM, Hamann LG, Horn EJ, Oberg KM, Scholes GD, Hyster TK. Quaternary Charge-Transfer Complex Enables Photoenzymatic Intermolecular Hydroalkylation of Olefins. Journal of the American Chemical Society. PMID 33369395 DOI: 10.1021/jacs.0c11462  0.766
2020 Clayman PD, Hyster TK. Photoenzymatic Generation of Unstabilized Alkyl Radicals: An Asymmetric Reductive Cyclization. Journal of the American Chemical Society. PMID 32857506 DOI: 10.1021/Jacs.0C07918  0.303
2020 DeHovitz JS, Loh YY, Kautzky JA, Nagao K, Meichan AJ, Yamauchi M, MacMillan DWC, Hyster TK. Static to inducibly dynamic stereocontrol: The convergent use of racemic β-substituted ketones. Science (New York, N.Y.). 369: 1113-1118. PMID 32855338 DOI: 10.1126/Science.Abc9909  0.362
2020 Hyster T, Nakano Y, Black MJ, Meichan AJ, Sandoval BA, Chung M, Biegasiewicz K, Zhu T. Photoenzymatic Hydrogenation of Heteroaromatic Olefins using 'Ene'-Reductases with Photoredox Catalysts. Angewandte Chemie (International Ed. in English). PMID 32181943 DOI: 10.1002/Anie.202003125  0.47
2020 Sandoval BA, Hyster TK. Emerging strategies for expanding the toolbox of enzymes in biocatalysis. Current Opinion in Chemical Biology. 55: 45-51. PMID 31935627 DOI: 10.1016/J.Cbpa.2019.12.006  0.44
2020 Hyster TK. Cluster Preface: Biocatalysis Synlett. 31: 223-223. DOI: 10.1055/S-0039-1691581  0.359
2020 Hyster TK. Radical Biocatalysis: Using Non-Natural Single Electron Transfer Mechanisms to Access New Enzymatic Functions Synlett. 31: 248-254. DOI: 10.1055/S-0037-1611818  0.48
2019 Black MJ, Biegasiewicz KF, Meichan AJ, Oblinsky DG, Kudisch B, Scholes GD, Hyster TK. Asymmetric redox-neutral radical cyclization catalysed by flavin-dependent 'ene'-reductases. Nature Chemistry. PMID 31792387 DOI: 10.1038/S41557-019-0370-2  0.521
2019 Biegasiewicz KF, Cooper SJ, Gao X, Oblinsky DG, Kim JH, Garfinkle SE, Joyce LA, Sandoval BA, Scholes GD, Hyster TK. Photoexcitation of flavoenzymes enables a stereoselective radical cyclization. Science (New York, N.Y.). 364: 1166-1169. PMID 31221855 DOI: 10.1126/Science.Aaw1143  0.658
2019 Hyster T, Sandoval B, Kurtoic S, Chung M, Biegasiewicz K. Photoenzymatic Catalysis Enables Radical- Mediated Ketone Reduction in 'Ene'-Reductases. Angewandte Chemie (International Ed. in English). PMID 30951226 DOI: 10.1002/Anie.201902005  0.519
2018 Hyster TK, Dalton DM, Rovis T. Correction: Ligand design for Rh(iii)-catalyzed C-H activation: an unsymmetrical cyclopentadienyl group enables a regioselective synthesis of dihydroisoquinolones. Chemical Science. 9: 8024. PMID 30542552 DOI: 10.1039/C8Sc90195C  0.762
2018 Nakano Y, Biegasiewicz KF, Hyster TK. Biocatalytic hydrogen atom transfer: an invigorating approach to free-radical reactions. Current Opinion in Chemical Biology. 49: 16-24. PMID 30269010 DOI: 10.1016/J.Cbpa.2018.09.001  0.449
2018 Biegasiewicz KF, Cooper SJ, Emmanuel MA, Miller DC, Hyster TK. Catalytic promiscuity enabled by photoredox catalysis in nicotinamide-dependent oxidoreductases. Nature Chemistry. PMID 29892028 DOI: 10.1038/S41557-018-0059-Y  0.655
2017 Hyster TK, Dalton DM, Rovis T. Correction: Ligand design for Rh(iii)-catalyzed C-H activation: an unsymmetrical cyclopentadienyl group enables a regioselective synthesis of dihydroisoquinolones. Chemical Science. 8: 1666. PMID 30123475 DOI: 10.1039/c6sc90080a  0.757
2017 Sandoval BA, Meichan AJ, Hyster TK. Enantioselective Hydrogen Atom Transfer: Discovery of Catalytic Promiscuity in Flavin-Dependent 'Ene'-Reductases. Journal of the American Chemical Society. PMID 28780870 DOI: 10.1021/Jacs.7B05468  0.396
2016 Emmanuel MA, Greenberg NR, Oblinsky DG, Hyster TK. Accessing non-natural reactivity by irradiating nicotinamide-dependent enzymes with light. Nature. 540: 414-417. PMID 27974767 DOI: 10.1038/Nature20569  0.471
2016 Hyster TK, Ward TR. Genetic Optimization of Metalloenzymes: Enhancing Enzymes for Non-Natural Reactions. Angewandte Chemie (International Ed. in English). PMID 26971363 DOI: 10.1002/Anie.201508816  0.362
2016 Prier CK, Hyster TK, Farwell CC, Huang A, Arnold FH. Asymmetric Enzymatic Synthesis of Allylic Amines: A Sigmatropic Rearrangement Strategy. Angewandte Chemie (International Ed. in English). PMID 26970325 DOI: 10.1002/Anie.201601056  0.776
2015 Farwell CC, Zhang RK, McIntosh JA, Hyster TK, Arnold FH. Enantioselective Enzyme-Catalyzed Aziridination Enabled by Active-Site Evolution of a Cytochrome P450. Acs Central Science. 1: 89-93. PMID 26405689 DOI: 10.1021/Acscentsci.5B00056  0.768
2015 Hyster TK, Rovis T. Correction: Pyridine synthesis from oximes and alkynes via rhodium(III) catalysis: Cp* and Cp(t) provide complementary selectivity. Chemical Communications (Cambridge, England). 51: 5778. PMID 25749239 DOI: 10.1039/c5cc90120k  0.535
2015 Hyster TK, Dalton DM, Rovis T. Ligand Design for Rh(III)-Catalyzed C-H Activation: An Unsymmetrical Cyclopentadienyl Enables a Regioselective Synthesis of Dihydroisoquinolones. Chemical Science (Royal Society of Chemistry : 2010). 6: 254-258. PMID 25489470 DOI: 10.1039/C4Sc02590C  0.762
2015 Hyster TK. High-Valent Co(III)- and Ni(II)-Catalyzed C–H Activation Catalysis Letters. 145: 458-467. DOI: 10.1007/S10562-014-1449-4  0.378
2015 Hyster TK, Arnold FH. P450BM3-axial mutations: A gateway to non-natural reactivity Israel Journal of Chemistry. 55: 14-20. DOI: 10.1002/Ijch.201400080  0.619
2015 Hyster TK. ChemInform Abstract: High-Valent Co(III)- and Ni(II)-Catalyzed C-H Activation Cheminform. 46: no-no. DOI: 10.1002/CHIN.201513314  0.31
2014 Hyster TK, Farwell CC, Buller AR, McIntosh JA, Arnold FH. Enzyme-controlled nitrogen-atom transfer enables regiodivergent C-H amination. Journal of the American Chemical Society. 136: 15505-8. PMID 25325618 DOI: 10.1021/Ja509308V  0.748
2014 Farwell CC, McIntosh JA, Hyster TK, Wang ZJ, Arnold FH. Enantioselective imidation of sulfides via enzyme-catalyzed intermolecular nitrogen-atom transfer. Journal of the American Chemical Society. 136: 8766-71. PMID 24901646 DOI: 10.1021/Ja503593N  0.782
2013 Hyster TK, Rovis T. Rhodium(III)-Catalyzed C-H Activation Mediated Synthesis of Isoquinolones from Amides and Cyclopropenes. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 24: 1842-1844. PMID 25346576 DOI: 10.1055/S-0033-1339510  0.658
2013 Davis TA, Hyster TK, Rovis T. Rhodium(III)-catalyzed intramolecular hydroarylation, amidoarylation, and Heck-type reaction: three distinct pathways determined by an amide directing group. Angewandte Chemie (International Ed. in English). 52: 14181-5. PMID 24214733 DOI: 10.1002/Anie.201307631  0.723
2013 Hyster TK, Ruhl KE, Rovis T. A coupling of benzamides and donor/acceptor diazo compounds to form γ-lactams via Rh(III)-catalyzed C-H activation. Journal of the American Chemical Society. 135: 5364-7. PMID 23548055 DOI: 10.1021/Ja402274G  0.615
2012 Hyster TK, Knörr L, Ward TR, Rovis T. Biotinylated Rh(III) complexes in engineered streptavidin for accelerated asymmetric C-H activation. Science (New York, N.Y.). 338: 500-3. PMID 23112327 DOI: 10.1126/Science.1226132  0.663
2011 Hyster TK, Rovis T. An Improved Catalyst Architecture for Rhodium (III) Catalyzed C-H Activation and its Application to Pyridone Synthesis. Chemical Science (Royal Society of Chemistry : 2010). 2: 1606-1610. PMID 25580208 DOI: 10.1039/C1Sc00235J  0.642
2011 Du Y, Hyster TK, Rovis T. Rhodium(III)-catalyzed oxidative carbonylation of benzamides with carbon monoxide. Chemical Communications (Cambridge, England). 47: 12074-6. PMID 22006288 DOI: 10.1039/C1Cc15843K  0.663
2011 Hyster TK, Rovis T. Pyridine synthesis from oximes and alkynes via rhodium(III) catalysis: Cp* and Cp(t) provide complementary selectivity. Chemical Communications (Cambridge, England). 47: 11846-8. PMID 21986995 DOI: 10.1039/C1Cc15248C  0.605
2011 Du Y, Hyster TK, Rovis T. Rhodium-catalyzed oxidative carbonylation of benzamides with CO under mild conditions Acs National Meeting Book of Abstracts 0.48
2010 Hyster TK, Rovis T. Rhodium-catalyzed oxidative cycloaddition of benzamides and alkynes via C-H/N-H activation. Journal of the American Chemical Society. 132: 10565-9. PMID 20662529 DOI: 10.1021/Ja103776U  0.661
2009 Wentzel MT, Reddy VJ, Hyster TK, Douglas CJ. Chemoselectivity in catalytic C-C and C-H bond activation: controlling intermolecular carboacylation and hydroarylation of alkenes. Angewandte Chemie (International Ed. in English). 48: 6121-3. PMID 19591181 DOI: 10.1002/Anie.200902215  0.627
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