Year |
Citation |
Score |
2022 |
Hill MD, Fang H, Norris D, Delucca GV, Huang H, DeBenedetto M, Quesnelle C, Schmitz WD, Tokarski JS, Sheriff S, Yan C, Fanslau C, Haarhoff Z, Huang C, Kramer M, et al. Development of BET Inhibitors as Potential Treatments for Cancer: Optimization of Pharmacokinetic Properties. Acs Medicinal Chemistry Letters. 13: 1165-1171. PMID 35859878 DOI: 10.1021/acsmedchemlett.2c00219 |
0.702 |
|
2012 |
Li J, Smith D, Krishnananthan S, Hartz RA, Dasgupta B, Ahuja V, Schmitz WD, Bronson JJ, Mathur A, Barrish JC, Chen BC. An efficient, direct bis-ortho-chlorination of 4-(difluoromethoxy)aniline and its application to the synthesis of BMS-665053, a potent and selective pyrazinone-containing corticotropin-releasing factor-1 receptor antagonist Organic Process Research and Development. 16: 156-159. DOI: 10.1021/op2003198 |
0.378 |
|
2010 |
Schmitz WD, Brenner AB, Bronson JJ, Ditta JL, Griffin CR, Li YW, Lodge NJ, Molski TF, Olson RE, Zhuo X, Macor JE. 5-arylamino-1,2,4-triazin-6(1H)-one CRF1 receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 20: 3579-83. PMID 20483614 DOI: 10.1016/j.bmcl.2010.04.121 |
0.736 |
|
2010 |
Hartz RA, Ahuja VT, Schmitz WD, Molski TF, Mattson GK, Lodge NJ, Bronson JJ, Macor JE. Synthesis and structure-activity relationships of N3-pyridylpyrazinones as corticotropin-releasing factor-1 (CRF1) receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 20: 1890-4. PMID 20176478 DOI: 10.1016/j.bmcl.2010.01.129 |
0.74 |
|
2010 |
SCHMITZ WD, ROMO D. ChemInform Abstract: A New Route to 2-Substituted δ2-Thiazolines: Stille Cross- Couplings of 2-Bromo-δ2-thiazolines. Cheminform. 27: no-no. DOI: 10.1002/chin.199641132 |
0.589 |
|
2009 |
Hartz RA, Ahuja VT, Arvanitis AG, Rafalski M, Yue EW, Denhart DJ, Schmitz WD, Ditta JL, Deskus JA, Brenner AB, Hobbs FW, Payne J, Lelas S, Li YW, Molski TF, et al. Synthesis, structure-activity relationships, and in vivo evaluation of N3-phenylpyrazinones as novel corticotropin-releasing factor-1 (CRF1) receptor antagonists. Journal of Medicinal Chemistry. 52: 4173-91. PMID 19552437 DOI: 10.1021/Jm900301Y |
0.744 |
|
2009 |
Hartz RA, Ahuja VT, Rafalski M, Schmitz WD, Brenner AB, Denhart DJ, Ditta JL, Deskus JA, Yue EW, Arvanitis AG, Lelas S, Li YW, Molski TF, Wong H, Grace JE, et al. In vitro intrinsic clearance-based optimization of N3-phenylpyrazinones as corticotropin-releasing factor-1 (CRF1) receptor antagonists. Journal of Medicinal Chemistry. 52: 4161-72. PMID 19552436 DOI: 10.1021/Jm900302Q |
0.733 |
|
2009 |
Hartz RA, Ahuja VT, Rafalski M, Schmitz WD, Brenner AB, Denhart DJ, Ditta JL, Deskus JA, Yue EW, Arvanitis AG, Lelas S, Li YW, Molski TF, Wong H, Grace JE, et al. Corrections to in vitro intrinsic clearance-based optimization of N 3-phenylpyrazinones as corticotropin-releasing factor-1 (CRF 1) receptor antagonists (Journal of Medicinal Chemistry (2009) 52, (4161-4172) DOI: 10.1021/jm900302q] Journal of Medicinal Chemistry. 52: 5770. DOI: 10.1021/Jm9011033 |
0.353 |
|
2005 |
Schmitz WD, Denhart DJ, Brenner AB, Ditta JL, Mattson RJ, Mattson GK, Molski TF, Macor JE. Homotryptamines as potent and selective serotonin reuptake inhibitors (SSRIs). Bioorganic & Medicinal Chemistry Letters. 15: 1619-21. PMID 15745809 DOI: 10.1016/j.bmcl.2005.01.059 |
0.712 |
|
2000 |
Romo D, Rzasa RM, Schmitz WD, Yang J, Cohn ST, Buchler IP, Shea HA, Park K, Langenhan JM, Messerschmidt NB, Cox MM. Total synthesis of marine natural products driven by novel structure, potent biological activity, and/or synthetic methodology. Ernst Schering Research Foundation Workshop. 103-48. PMID 11077607 |
0.713 |
|
2000 |
Dvorak CA, Schmitz WD, Poon DJ, Pryde DC, Lawson JP, Amos RA, Meyers AI. The Synthesis of Streptogramin Antibiotics: (-)-Griseoviridin and Its C-8 Epimer Financial support has been provided by the National Institutes of Health (NIH). We thank the NIH for financial support of this study and Drs. Russell Linderman, Donald Walker, Ronald Spohn, and Enrico Marcantoni for their assistance in various stages of this effort. Angewandte Chemie (International Ed. in English). 39: 1664-1666. PMID 10820470 DOI: 10.1002/(Sici)1521-3773(20000502)39:9<1664::Aid-Anie1664>3.0.Co;2-# |
0.494 |
|
1998 |
Schmitz WD, Messerschmidt NB, Romo D. A β-lactone-based strategy applied to the total synthesis of (8S,21S,22S,23R)- and (8R,21S,22S,23R)-okinonellin B Journal of Organic Chemistry. 63: 2058-2059. DOI: 10.1021/Jo9722360 |
0.57 |
|
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