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John DiGiovanni, PhD - Publications

Affiliations: 
University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Pharmacology and Toxicology
Website:
https://www.utexas.edu/pharmacy/divisions/pharmtox/faculty/digiovanni.html

322 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Schirmer AU, Driver LM, Zhao MT, Wells CI, Pickett JE, O'Bryne SN, Eduful BJ, Yang X, Howard L, You S, Devi GR, DiGiovanni J, Freedland SJ, Chi JT, Drewry DH, et al. Non-canonical role of Hippo tumor suppressor serine/threonine kinase 3 STK3 in prostate cancer. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 34450249 DOI: 10.1016/j.ymthe.2021.08.029  1
2021 Su F, Daquinag AC, Ahn S, Saha A, Dai Y, Zhao Z, DiGiovanni J, Kolonin MG. Progression of prostate carcinoma is promoted by adipose stromal cell-secreted CXCL12 signaling in prostate epithelium. Npj Precision Oncology. 5: 26. PMID 33753872 DOI: 10.1038/s41698-021-00160-9  1
2021 Eguiarte-Solomon F, Blazanin N, Rho O, Carbajal S, Felsher DW, Tran PT, DiGiovanni J. Twist1 is required for the development of UVB-induced squamous cell carcinoma. Molecular Carcinogenesis. PMID 33713497 DOI: 10.1002/mc.23296  1
2021 Dimachkie MD, Bechtel MD, Robertson HL, Michel C, Lee EK, Sullivan DK, Chalise P, Thrasher JB, Parker WP, Godwin AK, Pathak HB, DiGiovanni J, Shivappa N, Hébert JR, Hamilton-Reeves JM. Exploration of biomarkers from a pilot weight management study for men undergoing radical prostatectomy. Urologic Oncology. PMID 33563536 DOI: 10.1016/j.urolonc.2021.01.010  0.04
2020 Hackman GL, Collins M, Lu X, Lodi A, DiGiovanni J, Tiziani S. Predicting and Quantifying Antagonistic Effects of Natural Compounds Given with Chemotherapeutic Agents: Applications for High-Throughput Screening. Cancers. 12. PMID 33322034 DOI: 10.3390/cancers12123714  0.01
2020 Saha A, Zhao S, Chen Z, Georgiou G, Stone E, Kidane D, DiGiovanni J. Combinatorial Approaches to Enhance DNA Damage Following Enzyme-mediated Depletion of L-Cyst(e)ine for Treatment of Pancreatic Cancer. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 33091613 DOI: 10.1016/j.ymthe.2020.10.016  1
2020 Lu WC, Saha A, Yan W, Garrison K, Lamb C, Pandey R, Irani S, Lodi A, Lu X, Tiziani S, Zhang YJ, Georgiou G, DiGiovanni J, Stone E. Enzyme-mediated depletion of serum l-Met abrogates prostate cancer growth via multiple mechanisms without evidence of systemic toxicity. Proceedings of the National Academy of Sciences of the United States of America. PMID 32434918 DOI: 10.1073/Pnas.1917362117  1
2019 Rourke E, Sunnapwar A, Mais D, Kukkar V, DiGiovanni J, Kaushik D, Liss MA. Inflammation appears as high Prostate Imaging-Reporting and Data System scores on prostate magnetic resonance imaging (MRI) leading to false positive MRI fusion biopsy. Investigative and Clinical Urology. 60: 388-395. PMID 31501802 DOI: 10.4111/Icu.2019.60.5.388  0.01
2019 Kolonin MG, DiGiovanni J. The role of adipose stroma in prostate cancer aggressiveness. Translational Andrology and Urology. 8: S348-S350. PMID 31392166 DOI: 10.21037/Tau.2019.04.07  0.04
2019 Morales LD, Archbold AK, Olivarez S, Slaga TJ, DiGiovanni J, Kim DJ. The role of T-cell protein tyrosine phosphatase in epithelial carcinogenesis. Molecular Carcinogenesis. PMID 31264291 DOI: 10.1002/Mc.23078  1
2019 Khandelwal AR, Kent B, Hillary S, Alam MM, Ma X, Gu X, DiGiovanni J, Nathan CO. Fibroblast growth factor receptor promotes progression of cutaneous squamous cell carcinoma. Molecular Carcinogenesis. PMID 31254372 DOI: 10.1002/Mc.23012  0.04
2019 Blazanin N, Cheng T, Carbajal S, DiGiovanni J. Activation of a protumorigenic IFNγ/STAT1/IRF-1 signaling pathway in keratinocytes following exposure to solar ultraviolet light. Molecular Carcinogenesis. PMID 31237385 DOI: 10.1002/Mc.23073  1
2019 Kshattry S, Saha A, Gries P, Tiziani S, Stone E, Georgiou G, DiGiovanni J. Enzyme-mediated depletion of l-cyst(e)ine synergizes with thioredoxin reductase inhibition for suppression of pancreatic tumor growth. Npj Precision Oncology. 3: 16. PMID 31231686 DOI: 10.1038/s41698-019-0088-z  1
2019 Harrison DE, Strong R, Alavez S, Astle CM, DiGiovanni J, Fernandez E, Flurkey K, Garratt M, Gelfond JAL, Javors MA, Levi M, Lithgow GJ, Macchiarini F, Nelson JF, Sukoff Rizzo SJ, et al. Acarbose improves health and lifespan in aging HET3 mice. Aging Cell. e12898. PMID 30688027 DOI: 10.1111/Acel.12898  1
2019 Eguiarte-Solomon F, Rho O, DiGiovanni J. Abstract 4647: Keratinocyte specific deletion of TWIST1 promotes differentiation and inhibits UVB-induced hyperproliferation Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-4647  1
2019 Wilder CS, Saha A, Georgiou G, Stone E, DiGiovanni J. Abstract 2996: Systemic depletion of L-methionine with an engineered human enzyme for the treatment of melanoma Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-2996  1
2019 Ahn S, Saha A, Kolonin MG, DiGiovanni J. Abstract 1966: Obesity and prostate cancer progression: Role of the chemokine CXCL12 Cancer Research. 79: 1966-1966. DOI: 10.1158/1538-7445.Am2019-1966  1
2018 Liss MA, Al-Bayati O, Gelfond J, Goros M, Ullevig S, DiGiovanni J, Hamilton-Reeves J, O'Keefe D, Bacich D, Weaver B, Leach R, Thompson IM. Higher baseline dietary fat and fatty acid intake is associated with increased risk of incident prostate cancer in the SABOR study. Prostate Cancer and Prostatic Diseases. PMID 30385837 DOI: 10.1038/S41391-018-0105-2  0.01
2018 Su F, Ahn S, Saha A, DiGiovanni J, Kolonin MG. Adipose stromal cell targeting suppresses prostate cancer epithelial-mesenchymal transition and chemoresistance. Oncogene. PMID 30361686 DOI: 10.1038/S41388-018-0558-8  1
2018 Tremmel L, Rho O, Slaga TJ, DiGiovanni J. Inhibition of Skin Tumor Promotion by TPA Using a Combination of Topically Applied Ursolic Acid and Curcumin. Molecular Carcinogenesis. PMID 30346064 DOI: 10.1002/Mc.22918  1
2018 Mancha-Ramirez AM, Yang X, Liang H, Junco J, Lee KP, Bovio SF, Espinoza M, Wool J, Slaga A, Glade DC, Hanes M, Malik G, Kim DJ, DiGiovanni J, Slaga TJ. Harnessing the gatekeepers of glucocorticoids for chemoprevention of non-melanoma skin cancer. Molecular Carcinogenesis. PMID 30302860 DOI: 10.1002/Mc.22912  1
2018 Junco JJ, Cho J, Mancha A, Malik G, Wei SJ, Kim DJ, Liang H, DiGiovanni J, Slaga TJ. Role of AMPK and PPARα in the anti-skin cancer effects of ursolic acid. Molecular Carcinogenesis. PMID 30129681 DOI: 10.1002/Mc.22890  1
2018 Liss MA, Rickborn L, DiGiovanni J, Bacich D, DeGraffenried LA, Parihar M, Thompson IM, Sharp ZD. mTOR inhibitors for treatment of low-risk prostate cancer. Medical Hypotheses. 117: 63-68. PMID 30077200 DOI: 10.1016/J.Mehy.2018.06.004  0.01
2018 Lengyel E, Makowski L, DiGiovanni J, Kolonin MG. Cancer as a Matter of Fat: The Crosstalk between Adipose Tissue and Tumors. Trends in Cancer. 4: 374-384. PMID 29709261 DOI: 10.1016/J.Trecan.2018.03.004  0.01
2018 Ahn S, Saha A, Kolonin MG, DiGiovanni J. Abstract 5121: Obesity and prostate cancer progression: Role of the chemokine CXCL12 Cancer Research. 78: 5121-5121. DOI: 10.1158/1538-7445.Am2018-5121  1
2018 Kshattry S, Georgiou G, Tiziani S, Saha A, Stone E, DiGiovanni J. Abstract 3963: Cystine depleting human enzyme combined with auranofin synergistically inhibits pancreatic cancer cell growth in vitro and in vivo Cancer Research. 78: 3963-3963. DOI: 10.1158/1538-7445.Am2018-3963  1
2018 Tremmel L, Rho O, DiGiovanni J. Abstract 278: Inhibition of skin tumor promotion by TPA using a combination of topically applied ursolic acid and curcumin Prevention and Research. DOI: 10.1158/1538-7445.Am2018-278  1
2017 Lodi A, Saha A, Lu X, Wang B, Sentandreu E, Collins M, Kolonin MG, DiGiovanni J, Tiziani S. Erratum: Combinatorial treatment with natural compounds in prostate cancer inhibits prostate tumor growth and leads to key modulations of cancer cell metabolism. Npj Precision Oncology. 1: 30. PMID 29873330 DOI: 10.1038/s41698-017-0027-9  1
2017 Kim M, Morales LD, Baek M, Slaga TJ, DiGiovanni J, Kim DJ. UVB-induced nuclear translocation of TC-PTP by AKT/14-3-3σ axis inhibits keratinocyte survival and proliferation. Oncotarget. 8: 90674-90692. PMID 29207596 DOI: 10.18632/Oncotarget.21794  1
2017 Lodi A, Saha A, Lu X, Wang B, Sentandreu E, Collins M, Kolonin MG, DiGiovanni J, Tiziani S. Combinatorial treatment with natural compounds in prostate cancer inhibits prostate tumor growth and leads to key modulations of cancer cell metabolism. Npj Precision Oncology. 1. PMID 29202102 DOI: 10.1038/s41698-017-0024-z  1
2017 Rossi EL, Khatib SA, Doerstling SS, Bowers LW, Pruski M, Ford NA, Glickman RD, Niu M, Yang P, Cui Z, DiGiovanni J, Hursting SD. Resveratrol inhibits obesity-associated adipose tissue dysfunction and tumor growth in a mouse model of postmenopausal claudin-low breast cancer. Molecular Carcinogenesis. PMID 29197120 DOI: 10.1002/Mc.22763  1
2017 Saha A, Ahn S, Blando J, Su F, Kolonin MG, DiGiovanni J. Proinflammatory CXCL12-CXCR4/CXCR7 signaling axis drives Myc-induced prostate cancer in obese mice. Cancer Research. PMID 28687617 DOI: 10.1158/0008-5472.Can-17-0284  1
2017 Lee H, Kim M, Baek M, Morales LD, Jang IS, Slaga TJ, DiGiovanni J, Kim DJ. Targeted disruption of TC-PTP in the proliferative compartment augments STAT3 and AKT signaling and skin tumor development. Scientific Reports. 7: 45077. PMID 28322331 DOI: 10.1038/Srep45077  1
2017 Tremmel L, Rho O, DiGiovanni J. Abstract 5262: The inhibitory effect of combinations of curcumin, ursolic acid, and metformin on skin tumor promotion by TPA Cancer Research. 77: 5262-5262. DOI: 10.1158/1538-7445.Am2017-5262  1
2017 Khandelwal AR, Rong X, Moore-Medlin T, Ma X, Warner A, DiGiovanni J, Nathan CO. Abstract 4799: Fibroblast growth factor receptor (FGFR) promotes progression of cutaneous squamous cell carcinoma Cancer Research. 77: 4799-4799. DOI: 10.1158/1538-7445.Am2017-4799  0.01
2017 Saha A, Cramer SL, Kshattry S, Tiziani S, Stone E, Georgiou G, DiGiovanni J. Abstract 2132: Novel therapeutic approach through systemic depletion of L-cyst(e)ine with engineered cyst(e)inase enzyme for suppression of prostate tumor growth Cancer Research. 77: 2132-2132. DOI: 10.1158/1538-7445.Am2017-2132  1
2017 Kshattry S, Saha A, Cramer S, DiGiovanni J, Tiziani S, Munoz N, Georgiou G, Stone E. Abstract 105: Depletion of extracellular cystine and cysteine by a mutagenized human enzyme causes ROS mediated cytotoxicity in pancreatic cancer cells Cancer Research. 77: 105-105. DOI: 10.1158/1538-7445.Am2017-105  1
2016 Cramer SL, Saha A, Liu J, Tadi S, Tiziani S, Yan W, Triplett K, Lamb C, Alters SE, Rowlinson S, Zhang YJ, Keating MJ, Huang P, DiGiovanni J, Georgiou G, et al. Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth. Nature Medicine. PMID 27869804 DOI: 10.1038/Nm.4232  1
2016 Rho O, Srivastava J, Cho J, DiGiovanni J. Overexpression of PRAS40(T246A) in the Proliferative Compartment Suppresses mTORC1 Signaling, Keratinocyte Migration and Skin Tumor Development. The Journal of Investigative Dermatology. PMID 27349859 DOI: 10.1016/J.Jid.2016.06.013  1
2016 Saha A, Blando J, Fernandez I, Kiguchi K, DiGiovanni J. Linneg Sca-1high CD49fhigh prostate cancer cells derived from the Hi-Myc mouse model are tumor-initiating cells with basal-epithelial characteristics and differentiation potential in vitro and in vivo. Oncotarget. PMID 26910370 DOI: 10.18632/Oncotarget.7535  1
2016 Lomada D, Jain M, Bolner M, Reeh KA, Kang R, Reddy MC, DiGiovanni J, Richie ER. Stat3 Signaling Promotes Survival And Maintenance Of Medullary Thymic Epithelial Cells. Plos Genetics. 12: e1005777. PMID 26789196 DOI: 10.1371/Journal.Pgen.1005777  1
2016 Lee H, Kim M, Morales LD, Slaga TJ, DiGiovanni J, Kim DJ. Abstract 4071: Targeted disruption of T-cell protein tyrosine phosphatase in mouse epidermis reveals its critical role in chemically-induced skin carcinogenesis Cancer Research. 76: 4071-4071. DOI: 10.1158/1538-7445.Am2016-4071  1
2016 Lu X, Wang B, Saha A, Sentandreu E, Lodi A, DiGiovanni J, Tiziani S. Abstract 12: Combinatorial intervention with natural compounds induces key metabolic modulations for prostate cancer prevention and treatment Cancer Research. 76: 12-12. DOI: 10.1158/1538-7445.Am2016-12  1
2015 Srivastava J, DiGiovanni J. Non-canonical Stat3 signaling in cancer. Molecular Carcinogenesis. PMID 26649644 DOI: 10.1002/Mc.22438  1
2015 Cooper RM, Shahzad A, Hasleton J, Digiovanni J, Hall MC, Todd DM, Modi S, Stables RH. Radiofrequency ablation of the interventricular septum to treat outflow tract gradients in hypertrophic obstructive cardiomyopathy: a novel use of CARTOSound® technology to guide ablation. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. PMID 26541709 DOI: 10.1093/europace/euv302  1
2015 Cho J, Tremmel L, Rho O, Camelio AM, Siegel D, Slaga TJ, DiGiovanni J. Evaluation of pentacyclic triterpenes found in Perilla frutescens for inhibition of skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate. Oncotarget. PMID 26513295 DOI: 10.18632/Oncotarget.5751  1
2015 Nowinski SM, Solmonson A, Rundhaug JE, Rho O, Cho J, Lago CU, Riley CL, Lee S, Kohno S, Dao CK, Nikawa T, Bratton SB, Wright CW, Fischer SM, DiGiovanni J, et al. Mitochondrial uncoupling links lipid catabolism to Akt inhibition and resistance to tumorigenesis. Nature Communications. 6: 8137. PMID 26310111 DOI: 10.1038/Ncomms9137  1
2015 Perez CJ, Mecklenburg L, Jaubert J, Martinez-Santamaria L, Iritani BM, Espejo A, Napoli E, Song G, Del Río M, DiGiovanni J, Giulivi C, Bedford MT, Dent SY, Wood RD, Kusewitt DF, et al. Increased Susceptibility to Skin Carcinogenesis Associated with a Spontaneous Mouse Mutation in the Palmitoyl Transferase Zdhhc13 Gene. The Journal of Investigative Dermatology. PMID 26288350 DOI: 10.1038/Jid.2015.314  1
2015 Nelson AT, Camelio AM, Claussen KR, Cho J, Tremmel L, DiGiovanni J, Siegel D. Synthesis of oxygenated oleanolic and ursolic acid derivatives with anti-inflammatory properties. Bioorganic & Medicinal Chemistry Letters. 25: 4342-6. PMID 26259803 DOI: 10.1016/J.Bmcl.2015.07.029  1
2015 Carlisle RT, Digiovanni J. Differential Diagnosis of the Swollen Red Eyelid. American Family Physician. 92: 106-12. PMID 26176369  0.01
2015 Schabath MB, DiGiovanni J. Introduction to special issue: Recent advances in mechanisms, prevention and treatment of lung cancer. Molecular Carcinogenesis. 54: vi. PMID 26089261 DOI: 10.1002/Mc.22337  1
2015 Srivastava J, Rho O, Youssef RM, DiGiovanni J. Twist1 regulates keratinocyte proliferation and skin tumor promotion. Molecular Carcinogenesis. PMID 26013710 DOI: 10.1002/Mc.22335  1
2015 DiGiovanni JJ, Riffle TL, Nagaraj NK. High- and low-frequency decrement contribution to spectral enhancement. American Journal of Audiology. PMID 25996845 DOI: 10.1044/2015_Aja-14-0087  1
2015 Lee H, Kim M, Morales LD, Riggs PK, DiGiovanni J, Kim DJ. Constitutive activation of Stat3 in mouse epidermis is linked to hair deficiency and cytoskeletal network damage. Experimental Dermatology. PMID 25940573 DOI: 10.1111/Exd.12744  1
2015 Saha A, Blando J, Tremmel L, DiGiovanni J. Effect of Metformin, Rapamycin, and Their Combination on Growth and Progression of Prostate Tumors in HiMyc Mice. Cancer Prevention Research (Philadelphia, Pa.). 8: 597-606. PMID 25908508 DOI: 10.1158/1940-6207.Capr-15-0014  1
2015 Nguyen J, Popovic M, Chow E, Cella D, Beaumont JL, Chu D, DiGiovanni J, Lam H, Pulenzas N, Bottomley A. EORTC QLQ-BR23 and FACT-B for the assessment of quality of life in patients with breast cancer: a literature review. Journal of Comparative Effectiveness Research. 4: 157-66. PMID 25825844 DOI: 10.2217/Cer.14.76  1
2015 Kitamura T, Srivastava J, Digiovanni J, Kiguchi K. Bile acid accelerates erbB2-induced pro-tumorigenic activities in biliary tract cancer Molecular Carcinogenesis. 54: 459-472. PMID 24839254 DOI: 10.1002/Mc.22118  1
2015 Bozeman R, Abel EL, Macias E, Cheng T, Beltran L, DiGiovanni J. A novel mechanism of skin tumor promotion involving interferon-gamma (IFNγ)/signal transducer and activator of transcription-1 (Stat1) signaling. Molecular Carcinogenesis. 54: 642-53. PMID 24464587 DOI: 10.1002/Mc.22132  1
2015 Rao D, Macias E, Carbajal S, Kiguchi K, DiGiovanni J. Constitutive Stat3 activation alters behavior of hair follicle stem and progenitor cell populations. Molecular Carcinogenesis. 54: 121-33. PMID 24038534 DOI: 10.1002/Mc.22080  1
2015 Saha A, Blando J, DiGiovanni J. Abstract 429: Novel role of CXCL12/CXCR4 signaling axis in obesity-induced prostate cancer progression in HiMyc mice Cancer Research. 75: 429-429. DOI: 10.1158/1538-7445.Am2015-429  1
2015 Srivastava J, Rho O, DiGiovanni J. Abstract 2106: Twist1 regulates keratinocyte stem cell proliferation and migration and is required for skin tumor formation Cancer Research. 75: 2106-2106. DOI: 10.1158/1538-7445.Am2015-2106  1
2015 Cho J, Rho O, Junco J, Slaga TJ, Camelio AM, Siegel D, DiGiovanni J. Abstract 1899: Anti-skin tumor promoting effects of pentacyclic triterpenes found in Perilla frutescens Cancer Research. 75: 1899-1899. DOI: 10.1158/1538-7445.Am2015-1899  1
2015 Nelson AT, Camelio AM, Claussen KR, Cho J, Tremmel L, DiGiovanni J, Siegel D. Synthesis of oxygenated oleanolic and ursolic acid derivatives with anti-inflammatory properties Bioorganic and Medicinal Chemistry Letters. DOI: 10.1016/j.bmcl.2015.07.029  1
2015 Schabath MB, Digiovanni J. Introduction to special issue: Recent advances in mechanisms, prevention and treatment of lung cancer Molecular Carcinogenesis. 54: 1. DOI: 10.1002/mc.22337  1
2015 Srivastava J, Rho O, Youssef RM, Digiovanni J. Twist1 regulates keratinocyte proliferation and skin tumor promotion Molecular Carcinogenesis. DOI: 10.1002/mc.22335  1
2015 Bozeman R, Abel EL, Macias E, Cheng T, Beltran L, DiGiovanni J. A novel mechanism of skin tumor promotion involving interferon-gamma (IFNγ)/signal transducer and activator of transcription-1 (Stat1) signaling Molecular Carcinogenesis. 54: 642-653. DOI: 10.1002/mc.22132  1
2015 Carlisle RT, Digiovanni J. Differential diagnosis of the swollen red eyelid American Family Physician. 92: 106-112.  1
2015 Fu G, Agarwal A, Popovic M, Lam M, Milakovic M, Fu W, Cheon S, DiGiovanni J, Chow R, Fu T, Lam H, Lechner B, Pulenzas N, Chow E. Survival benefit from palliative treatment in patients with advanced prostate cancer: A selected review Journal of Pain Management. 8: 299-306.  1
2015 DiGiovanni J, Popovic M, Chow E, Cella D, Beaumont JL, Nguyen J, Chu D, Adili A, Pulenzas N, Lechner B, Lam H, Bottomley A. Comparison of the EORTC QLQ-LC13 and the FACT-L for assessment of quality of life in patients with lung cancer Journal of Pain Management. 8: 103-113.  1
2014 Digiovanni J. Introduction to special issue: Mechanisms and targets for prevention and treatment of colorectal cancer Molecular Carcinogenesis. 53: vi. PMID 24738110 DOI: 10.1002/Mc.22143  1
2014 Suraneni MV, Moore JR, Zhang D, Badeaux M, Macaluso MD, DiGiovanni J, Kusewitt D, Tang DG. Tumor-suppressive functions of 15-Lipoxygenase-2 and RB1CC1 in prostate cancer. Cell Cycle (Georgetown, Tex.). 13: 1798-810. PMID 24732589 DOI: 10.4161/Cc.28757  1
2014 Angel JM, Abel EL, Riggs PK, McClellan SA, DiGiovanni J. Fine mapping reveals that promotion susceptibility locus 1 (Psl1) is a compound locus with multiple genes that modify susceptibility to skin tumor development G3 (Bethesda, Md.). 4: 1071-1079. PMID 24700353 DOI: 10.1534/G3.113.009688  1
2014 Saha A, Blando J, Silver E, Beltran L, Sessler J, DiGiovanni J. 6-Shogaol from dried ginger inhibits growth of prostate cancer cells both in vitro and in vivo through inhibition of STAT3 and NF-κB signaling Cancer Prevention Research. 7: 627-638. PMID 24691500 DOI: 10.1158/1940-6207.Capr-13-0420  1
2014 Macias E, Rao D, Carbajal S, Kiguchi K, DiGiovanni J. Stat3 binds to mtDNA and regulates mitochondrial gene expression in keratinocytes. The Journal of Investigative Dermatology. 134: 1971-80. PMID 24496235 DOI: 10.1038/Jid.2014.68  1
2014 Checkley LA, Rho O, Angel JM, Cho J, Blando J, Beltran L, Hursting SD, DiGiovanni J. Metformin inhibits skin tumor promotion in overweight and obese mice Cancer Prevention Research. 7: 54-64. PMID 24196830 DOI: 10.1158/1940-6207.Capr-13-0110  1
2014 Rho O, Kiguchi K, Jiang G, Digiovanni J. Impact of mTORC1 inhibition on keratinocyte proliferation during skin tumor promotion in wild-type and BK5.AktWT mice Molecular Carcinogenesis. 53: 871-882. PMID 24114993 DOI: 10.1002/Mc.22046  1
2014 Suraneni MV, Moore JR, Zhang D, Badeaux M, Macaluso MD, DiGiovanni J, Kusewitt D, Tang DG. Tumor-suppressive functions of 15-Lipoxygenase-2 and RB1CC1 in prostate cancer Cell Cycle. 13: 1-13. DOI: 10.4161/cc.28757  1
2014 Hirai T, Kanda T, Sato K, Takaishi M, Nakajima K, Yamamoto M, Kamijima R, DiGiovanni J, Sano S. Erratum: Cathepsin K is involved in development of psoriasis-like skin lesions through TLR-dependent Th17 activation (Journal of Immunology (2013) 190 (4805-4811)) Journal of Immunology. 192. DOI: 10.4049/Jimmunol.1490013  1
2014 Rho O, Cho J, DiGiovanni J. Abstract 5357: Targeting mTORC1 suppresses proliferation of keratinocyte stem cells and inhibits skin tumor promotion in mice Cancer Research. 74: 5357-5357. DOI: 10.1158/1538-7445.Am2014-5357  1
2014 Srivastava J, Macias E, Kiguchi K, DiGiovanni J. Abstract 5355: Twist1 regulates the cell cycle and proliferative capacity of keratinocytes during tumor promotion Cancer Research. 74: 5355-5355. DOI: 10.1158/1538-7445.Am2014-5355  1
2014 Saha A, Blando J, Silver E, Beltran L, Sessler J, DiGiovanni J. Abstract 2138: 6-Shogaol from dried ginger inhibits growth of prostate cancer cells both in vitro and in vivo Cancer Research. 74: 2138-2138. DOI: 10.1158/1538-7445.Am2014-2138  1
2014 Abel EL, DiGiovanni J. Environmental Carcinogenesis The Molecular Basis of Cancer: Fourth Edition. 103-128.e2. DOI: 10.1016/B978-1-4557-4066-6.00007-X  1
2013 DiGiovanni J, Angel JM. Introduction. Molecular Carcinogenesis. 52: E1. PMID 24155210 DOI: 10.1002/mc.22098  1
2013 Rodriguez BL, Blando JM, Lansakara-P DSP, Kiguchi Y, Digiovanni J, Cui Z. Antitumor activity of tumor-targeted RNA replicase-based plasmid that expresses interleukin-2 in a murine melanoma model Molecular Pharmaceutics. 10: 2404-2415. PMID 23641783 DOI: 10.1021/Mp400033M  1
2013 Macias E, Rao D, Digiovanni J. Role of stat3 in skin carcinogenesis: insights gained from relevant mouse models. Journal of Skin Cancer. 2013: 684050. PMID 23577258 DOI: 10.1155/2013/684050  1
2013 Hirai T, Kanda T, Sato K, Takaishi M, Nakajima K, Yamamoto M, Kamijima R, DiGiovanni J, Sano S. Cathepsin K is involved in development of psoriasis-like skin lesions through TLR-dependent Th17 activation Journal of Immunology. 190: 4805-4811. PMID 23543761 DOI: 10.4049/Jimmunol.1200901  1
2013 Lange SS, Bedford E, Reh S, Wittschieben JP, Carbajal S, Kusewitt DF, DiGiovanni J, Wood RD. Dual role for mammalian DNA polymerase ζ in maintaining genome stability and proliferative responses Proceedings of the National Academy of Sciences of the United States of America. 110: E687-E696. PMID 23386725 DOI: 10.1073/Pnas.1217425110  1
2013 Abel EL, Boulware S, Fields T, McIvor E, Powell KL, DiGiovanni J, Vasquez KM, MacLeod MC. Sulforaphane induces phase II detoxication enzymes in mouse skin and prevents mutagenesis induced by a mustard gas analog. Toxicology and Applied Pharmacology. 266: 439-42. PMID 23201461 DOI: 10.1016/J.Taap.2012.11.020  1
2013 Yokogawa M, Takaishi M, Nakajima K, Kamijima R, Digiovanni J, Sano S. Imiquimod attenuates the growth of UVB-Induced SCC in mice through Th1/Th17 cells Molecular Carcinogenesis. 52: 760-769. PMID 22431065 DOI: 10.1002/Mc.21901  1
2013 Nowinski SM, Rundhaug JE, Rho O, Lago CU, Fischer SM, DiGiovanni J, Mills EM. Abstract 5425: Epidermal respiratory uncoupling blocks skin carcinogenesis by inhibiting Akt. Cancer Research. 73: 5425-5425. DOI: 10.1158/1538-7445.Am2013-5425  1
2013 Saha A, Blando J, Kiguchi K, DiGiovanni J. Abstract 3704: Evaluation of curcumin in combination with 6-shogaol and epicatechin for the chemoprevention of prostate cancer. Cancer Research. 73: 3704-3704. DOI: 10.1158/1538-7445.Am2013-3704  1
2013 Blando JM, Kiguchi K, Fernandez I, DiGiovanni J. Abstract 179: Impact of diet-induced obesity on inflamatory pathways during prostate cancer progression in Hi-Myc mice. Cancer Research. 73: 179-179. DOI: 10.1158/1538-7445.Am2013-179  1
2013 Rho O, DiGiovanni J. Abstract 1302: Targeting mTORC1 by epidermal overexpression of PRAS40(T246A) suppresses TPA-induced epidermal hyperplasia during tumor promotion. Cancer Research. 73: 1302-1302. DOI: 10.1158/1538-7445.Am2013-1302  1
2013 Srivastava J, Macias E, Rao D, Kiguchi K, DiGiovanni J. Abstract 1290: Investigations to evaluate the role of Twist1 during tumor promotion and epithelial carcinogenesis. Cancer Research. 73: 1290-1290. DOI: 10.1158/1538-7445.Am2013-1290  1
2013 Ford NA, Digiovanni J, Hursting SD. Metabolic perturbations associated with adipose tissue dysfunction and the obesity-cancer link Adipose Tissue and Cancer. 1-14. DOI: 10.1007/978-1-4614-7660-3_1  1
2013 Gretz S, Poon M, Bedard G, Digiovanni J, Popovic M, Chow E. Intramedullary spinal cord metastasis from melanoma: A case report Journal of Pain Management. 6: 245-248.  1
2012 Carr TD, DiGiovanni J, Lynch CJ, Shantz LM. Inhibition of mTOR suppresses UVB-induced keratinocyte proliferation and survival Cancer Prevention Research. 5: 1394-1404. PMID 23129577 DOI: 10.1158/1940-6207.Capr-12-0272-T  1
2012 Hursting SD, Digiovanni J, Dannenberg AJ, Azrad M, Leroith D, Demark-Wahnefried W, Kakarala M, Brodie A, Berger NA. Obesity, energy balance, and cancer: new opportunities for prevention. Cancer Prevention Research (Philadelphia, Pa.). 5: 1260-72. PMID 23034147 DOI: 10.1158/1940-6207.Capr-12-0140  1
2012 Moore T, Beltran L, Carbajal S, Hursting SD, DiGiovanni J. Energy balance modulates mouse skin tumor promotion through altered IGF-1R and EGFR crosstalk Cancer Prevention Research. 5: 1236-1246. PMID 22896210 DOI: 10.1158/1940-6207.Capr-12-0234  1
2012 Popovic M, Lemke M, Zeng L, Chen E, Nguyen J, Thavarajah N, Digiovanni J, Caporusso F, Chow E. Comparing prognostic factors in patients with spinal metastases: A literature review Expert Review of Pharmacoeconomics and Outcomes Research. 12: 345-356. PMID 22812558 DOI: 10.1586/Erp.12.14  1
2012 Wonganan P, Chung WG, Zhu S, Kiguchi K, DiGiovanni J, Cui Z. Silencing of ribonucleotide reductase subunit M1 potentiates the antitumor activity of gemcitabine in resistant cancer cells Cancer Biology and Therapy. 13: 908-914. PMID 22785206 DOI: 10.4161/Cbt.20843  1
2012 Shen J, Abel EL, Riggs PK, Repass J, Hensley SC, Schroeder LJ, Temple A, Chau A, McClellan SA, Rho O, Kiguchi K, Ward MD, Semmes OJ, Person MD, Angel JM, ... Digiovanni J, et al. Proteomic and pathway analyses reveal a network of inflammatory genes associated with differences in skin tumor promotion susceptibility in DBA/2 and C57BL/6 mice. Carcinogenesis. 33: 2208-19. PMID 22782996 DOI: 10.1093/Carcin/Bgs213  1
2012 Batra V, Syed Z, Gill JN, Coburn MA, Adegboyega P, DiGiovanni J, Mathis JM, Shi R, Clifford JL, Kleiner-Hancock HE. Effects of the tropical ginger compound,1'-acetoxychavicol acetate, against tumor promotion in K5.Stat3C transgenic mice. Journal of Experimental & Clinical Cancer Research : Cr. 31: 57. PMID 22704648 DOI: 10.1186/1756-9966-31-57  1
2012 DiGiovanni J, Sun T, Sheng ZH. Characterizing synaptic vesicle proteins using synaptosomal fractions and cultured hippocampal neurons. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 2.7.1-22. PMID 22470148 DOI: 10.1002/0471142301.ns0207s59  1
2012 Perez C, Parker-Thornburg J, Mikulec C, Kusewitt DF, Fischer SM, Digiovanni J, Conti CJ, Benavides F. SKHIN/Sprd, a new genetically defined inbred hairless mouse strain for UV-induced skin carcinogenesis studies. Experimental Dermatology. 21: 217-20. PMID 22379968 DOI: 10.1111/J.1600-0625.2011.01430.X  1
2012 Kitamura T, Connolly K, Ruffino L, Ajiki T, Lueckgen A, DiGiovanni J, Kiguchi K. The therapeutic effect of histone deacetylase inhibitor PCI-24781 on gallbladder carcinoma in BK5.erbB2 mice Journal of Hepatology. 57: 84-91. PMID 22326466 DOI: 10.1016/J.Jhep.2012.01.018  1
2012 Rodriguez BL, Li X, Kiguchi K, Digiovanni J, Unger EC, Cui Z. Control of solid tumor growth in mice using EGF receptor-targeted RNA replicase-based plasmid DNA Nanomedicine. 7: 475-491. PMID 22296186 DOI: 10.2217/Nnm.11.112  1
2012 Lago CU, Nowinski SM, Rundhaug JE, Pfeiffer ME, Kiguchi K, Hirasaka K, Yang X, Abramson EM, Bratton SB, Rho O, Colavitti R, Kenaston MA, Nikawa T, Trempus C, Digiovanni J, et al. Mitochondrial respiratory uncoupling promotes keratinocyte differentiation and blocks skin carcinogenesis. Oncogene. 31: 4725-31. PMID 22266853 DOI: 10.1038/Onc.2011.630  1
2012 Tian J, Berton TR, Shirley SH, Lambertz I, Gimenez-Conti IB, DiGiovanni J, Korach KS, Conti CJ, Fuchs-Young R. Developmental stage determines estrogen receptor alpha expression and non-genomic mechanisms that control IGF-1 signaling and mammary proliferation in mice Journal of Clinical Investigation. 122: 192-204. PMID 22182837 DOI: 10.1172/Jci42204  1
2012 Yang G, Goltsov AA, Ren C, Kurosaka S, Edamura K, Logothetis R, DeMayo FJ, Troncoso P, Blando J, DiGiovanni J, Thompson TC. Caveolin-1 upregulation contributes to c-Myc-induced high-grade prostatic intraepithelial neoplasia and prostate cancer. Molecular Cancer Research : McR. 10: 218-29. PMID 22144662 DOI: 10.1158/1541-7786.Mcr-11-0451  1
2012 Miyoshi K, Takaishi M, DiGiovanni J, Sano S. Attenuation of psoriasis-like skin lesion in a mouse model by topical treatment with indirubin and its derivative E804 Journal of Dermatological Science. 65: 70-72. PMID 22051056 DOI: 10.1016/J.Jdermsci.2011.10.001  1
2012 Tian J, Lambertz I, Berton TR, Rundhaug JE, Kiguchi K, Shirley SH, Digiovanni J, Conti CJ, Fischer SM, Fuchs-Young R. Transgenic insulin-like growth factor-1 stimulates activation of COX-2 signaling in mammary glands Molecular Carcinogenesis. 51: 973-983. PMID 22006370 DOI: 10.1002/Mc.20868  1
2012 Sloat BR, Kiguchi K, Xiao G, Digiovanni J, Maury W, Cui Z. Transcutaneous DNA immunization following waxing-based hair depilation Journal of Controlled Release. 157: 94-102. PMID 21907253 DOI: 10.1016/J.Jconrel.2011.08.038  1
2012 Sandoval MA, Sloat BR, Lansakara-P. DSP, Kumar A, Rodriguez BL, Kiguchi K, Digiovanni J, Cui Z. EGFR-targeted stearoyl gemcitabine nanoparticles show enhanced anti-tumor activity Journal of Controlled Release. 157: 287-296. PMID 21871505 DOI: 10.1016/J.Jconrel.2011.08.015  1
2012 Benavides F, Perez C, Blando J, Contreras O, Shen J, Coussens LM, Fischer SM, Kusewitt DF, Digiovanni J, Conti CJ. Protective role of cathepsin L in mouse skin carcinogenesis Molecular Carcinogenesis. 51: 352-361. PMID 21538579 DOI: 10.1002/Mc.20792  1
2012 Saha A, Silver ES, Sessler JL, DiGiovanni J. Abstract 604: The ginger compound, 6-shogaol, inhibits prostate cancer cell growth through reduced activation of signal transducer and activator of transcription 3 (Stat3) Cancer Research. 72: 604-604. DOI: 10.1158/1538-7445.Am2012-604  1
2012 Blando JM, Kiguchi K, DiGiovanni J. Abstract 5423: Diet induced obesity, inflammation and prostate cancer progression in Hi-Myc mice Cancer Research. 72: 5423-5423. DOI: 10.1158/1538-7445.Am2012-5423  1
2012 Rao D, DiGiovanni J. Abstract 5216: Impact of Stat3 deletion or activation on keratinocyte stem/progenitor cells Cancer Research. 72: 5216-5216. DOI: 10.1158/1538-7445.Am2012-5216  1
2012 Rho O, Kiguchi K, DiGiovanni J. Abstract 2559: Targeting mTORC1 may provide selectivity for inhibiting proliferation of hair follicle stem/progenitor cells during tumor promotion Cancer Research. 72: 2559-2559. DOI: 10.1158/1538-7445.Am2012-2559  1
2012 Bozeman R, DiGiovanni J. Abstract 2556: Stat1 plays a major role in skin tumor promotion by chrysarobin but not TPA Cancer Research. 72: 2556-2556. DOI: 10.1158/1538-7445.Am2012-2556  1
2012 Lee YS, Smith LM, Slaga TJ, DiGiovanni J, Kim DJ. Abstract 2537: UVB irradiation induces nuclear translocation of TC-PTP in keratinocytes Cancer Research. 72: 2537-2537. DOI: 10.1158/1538-7445.Am2012-2537  1
2012 Cho J, Rho O, Carbajal S, Junco J, Slaga TJ, DiGiovanni J. Abstract 1596: Effect of combined treatment with ursolic acid (UA) and resveratrol (Res) on skin tumor promotion by TPA Cancer Research. 72: 1596-1596. DOI: 10.1158/1538-7445.Am2012-1596  1
2012 Kitamura T, Homma Y, DiGiovanni J, Kiguchi K. Abstract 1331: The BK5.erbB2 mouse as a novel model of esophageal adenocarcinoma Cancer Research. 72: 1331-1331. DOI: 10.1158/1538-7445.Am2012-1331  1
2012 Checkley A, Moore T, Rho O, DiGiovanni J. Abstract 1010: Effect of dietary energy balance modulation on the ability of metformin to inhibit skin tumor promotion Cancer Research. 72: 1010-1010. DOI: 10.1158/1538-7445.Am2012-1010  1
2012 Zhou M, Zeng L, Christakis M, Poon M, Chen E, Lauzon N, Thavarajah N, DiGiovanni J, Chow E. Unusual presentation of osteolytic bone metastases in prostate adenocarcinoma Journal of Pain Management. 5: 365-368.  1
2011 Blando J, Moore T, Hursting S, Jiang G, Saha A, Beltran L, Shen J, Repass J, Strom S, DiGiovanni J. Dietary energy balance modulates prostate cancer progression in Hi-Myc mice Cancer Prevention Research. 4: 2002-2014. PMID 21952584 DOI: 10.1158/1940-6207.Capr-11-0182  1
2011 DiGiovanni JJ, Davlin EA, Nagaraj NK. Effects of transient noise reduction algorithms on speech intelligibility and ratings of hearing aid users. American Journal of Audiology. 20: 140-50. PMID 21940982 DOI: 10.1044/1059-0889(2011/10-0007)  1
2011 Meves A, Geiger T, Zanivan S, DiGiovanni J, Mann M, Fässler R. Beta1 integrin cytoplasmic tyrosines promote skin tumorigenesis independent of their phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 108: 15213-8. PMID 21876123 DOI: 10.1073/Pnas.1105689108  1
2011 Moore T, Checkley LA, Digiovanni J. Dietary energy balance modulation of epithelial carcinogenesis: A role for IGF-1 receptor signaling and crosstalk Annals of the New York Academy of Sciences. 1229: 7-17. PMID 21793833 DOI: 10.1111/J.1749-6632.2011.06099.X  1
2011 Checkley LA, Rho O, Moore T, Hursting S, DiGiovanni J. Rapamycin is a potent inhibitor of skin tumor promotion by 12-O-ttradecanoylphorbol-13-aetate Cancer Prevention Research. 4: 1011-1020. PMID 21733825 DOI: 10.1158/1940-6207.Capr-10-0375  1
2011 Abel EL, Bubel JD, Simper MS, Powell L, McClellan SA, Andreeff M, MacLeod MC, DiGiovanni J. Protection against 2-chloroethyl ethyl sulfide (CEES) - induced cytotoxicity in human keratinocytes by an inducer of the glutathione detoxification pathway Toxicology and Applied Pharmacology. 255: 176-183. PMID 21723306 DOI: 10.1016/J.Taap.2011.06.012  1
2011 Tam CC, Dare DM, DiGiovanni JJ, Harrington AC, Deng AC. Recurrent and metastatic primary cutaneous mucinous carcinoma after excision and Mohs micrographic surgery. Cutis. 87: 245-8. PMID 21699128  0.01
2011 Swindell WR, Johnston A, Carbajal S, Han G, Wohn C, Lu J, Xing X, Nair RP, Voorhees JJ, Elder JT, Wang XJ, Sano S, Prens EP, DiGiovanni J, Pittelkow MR, et al. Genome-wide expression profiling of five mouse models identifies similarities and differences with human psoriasis. Plos One. 6: e18266. PMID 21483750 DOI: 10.1371/Journal.Pone.0018266  1
2011 Blando JM, Carbajal S, Abel E, Beltran L, Conti C, Fischer S, DiGiovanni J. Cooperation between Stat3 and Akt signaling leads to prostate tumor development in transgenic mice. Neoplasia (New York, N.Y.). 13: 254-65. PMID 21390188 DOI: 10.1593/Neo.101388  1
2011 Sloat BR, Sandoval MA, Li D, Chung WG, Lansakara-P DSP, Proteau PJ, Kiguchi K, Digiovanni J, Cui Z. In vitro and in vivo anti-tumor activities of a gemcitabine derivative carried by nanoparticles International Journal of Pharmaceutics. 409: 278-288. PMID 21371545 DOI: 10.1016/J.Ijpharm.2011.02.037  1
2011 Nakajima K, Kanda T, Takaishi M, Shiga T, Miyoshi K, Nakajima H, Kamijima R, Tarutani M, Benson JM, Elloso MM, Gutshall LL, Naso MF, Iwakura Y, DiGiovanni J, Sano S. Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesions in a mouse model. Journal of Immunology (Baltimore, Md. : 1950). 186: 4481-9. PMID 21346238 DOI: 10.4049/Jimmunol.1000148  1
2011 Benavides F, Blando J, Perez CJ, Garg R, Conti CJ, DiGiovanni J, Kazanietz MG. Transgenic overexpression of PKCε in the mouse prostate induces preneoplastic lesions Cell Cycle. 10: 268-277. PMID 21224724 DOI: 10.4161/Cc.10.2.14469  1
2011 Miyoshi K, Takaishi M, Nakajima K, Ikeda M, Kanda T, Tarutani M, Iiyama T, Asao N, Digiovanni J, Sano S. Stat3 as a therapeutic target for the treatment of psoriasis: A clinical feasibility study with STA-21, a Stat3 Inhibitor Journal of Investigative Dermatology. 131: 108-117. PMID 20811392 DOI: 10.1038/Jid.2010.255  1
2011 Rho O, Kim DJ, Kiguchi K, Digiovanni J. Growth factor signaling pathways as targets for prevention of epithelial carcinogenesis Molecular Carcinogenesis. 50: 264-279. PMID 20648549 DOI: 10.1002/Mc.20665  1
2011 Nakajima K, Kanda T, Takaishi M, Shiga T, Miyoshi K, Nakajima H, Kamijima R, Tarutani M, Benson JM, Elloso MM, Gutshall LL, Naso MF, Iwakura Y, DiGiovanni J, Sano S. Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesions in a mouse model (Journal of Immunology (2011) 186, (4481-4489)) Journal of Immunology. 187: 6157-6158. DOI: 10.4049/Jimmunol.1190071  1
2011 Junco J, Cho J, Malik G, Carbajal S, Moore T, Tolstykh O, DiGiovanni J, Slaga T. Abstract B59: A combination of resveratrol and ursolic acid produces synergistic inhibitory effects on markers of skin tumor promotion Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-B59  1
2011 Blando JM, Moore T, Beltran L, Jiang G, DiGiovanni J. Abstract 824: Altered growth factor and inflammatory signaling is associated with obesity related prostate cancer progression in HiMyc mice Cancer Research. 71: 824-824. DOI: 10.1158/1538-7445.Am2011-824  1
2011 Moore T, Beltran L, Hursting S, DiGiovanni J. Abstract 815: Dietary energy balance modulates skin tumor promotion through altered IGF-1R and EGFR crosstalk Cancer Research. 71: 815-815. DOI: 10.1158/1538-7445.Am2011-815  1
2011 Bozeman R, DiGiovanni J, Abel E. Abstract 2730: Role of Stat1 in skin tumor promotion Cancer Research. 71: 2730-2730. DOI: 10.1158/1538-7445.Am2011-2730  1
2011 Shen J, Abel EL, Riggs PK, Angel JM, Repass J, Hensley SC, Schroeder L, Traner A, Chau A, Ward M, Semmes OJ, Person MD, DiGiovanni J. Abstract 2729: Proteomic analysis reveals a network of inflammatory genes in epidermis associated with skin tumor promotion susceptibility in DBA/2 and C57BL/6 mice Cancer Research. 71: 2729-2729. DOI: 10.1158/1538-7445.Am2011-2729  1
2011 Checkley A, Rho O, Moore T, Hursting S, DiGiovanni J. Abstract 1847: Effect of rapamycin and metformin on skin tumor promotion in mice overweight and obese Cancer Research. 71: 1847-1847. DOI: 10.1158/1538-7445.Am2011-1847  1
2011 Abel EL, McIvor E, Bubel JD, Simper MS, Powell L, Fields TY, Andreeff M, MacLeod MC, DiGiovanni J. Abstract 1339: Upregulation of the glutathione detoxification pathway protects against cytotoxicity induced by the alkylating agent, 2-chloroethyl ethyl sulfide (CEES) Cancer Research. 71: 1339-1339. DOI: 10.1158/1538-7445.Am2011-1339  1
2011 DiGiovanni J, Prewitt JM, Nagaraj NK, Moates DR. The relative contribution to speech intelligibility from consonants and vowels using synthesized and naturally-spoken sentences Proceedings of Meetings On Acoustics. 11. DOI: 10.1121/1.3508176  1
2011 DiGiovanni JJ, Pratt RM. Response to Kuk Journal of the American Academy of Audiology. 22: 243-244. DOI: 10.1055/S-0040-1715373  1
2011 Abel EL, DiGiovanni J. Multistage carcinogenesis Current Cancer Research. 6: 27-51. DOI: 10.1007/978-1-61737-995-6_2  1
2011 Tam CC, Dare DM, DiGiovanni JJ, Harrington AC, Deng AC. Recurrent and metastatic primary cutaneous mucinous carcinoma after excision and Mohs micrographic surgery Cutis. 87: 245-248.  1
2010 Digiovanni JJ, Pratt RM. Verification of in situ thresholds and integrated real-ear measurements. Journal of the American Academy of Audiology. 21: 663-70. PMID 21376007 DOI: 10.3766/Jaaa.21.10.6  1
2010 Gregorio J, Meller S, Conrad C, Di Nardo A, Homey B, Lauerma A, Arai N, Gallo RL, DiGiovanni J, Gilliet M. Plasmacytoid dendritic cells sense skin injury and promote wound healing through type i interferons Journal of Experimental Medicine. 207: 2921-2930. PMID 21115688 DOI: 10.1084/Jem.20101102  1
2010 Abel EL, Angel JM, Riggs PK, Langfield L, Lo HH, Person MD, Awasthi YC, Wang LE, Strom SS, Wei Q, Digiovanni J. Evidence that Gsta4 modifies susceptibility to skin tumor development in mice and humans Journal of the National Cancer Institute. 102: 1663-1675. PMID 20966433 DOI: 10.1093/Jnci/Djq392  1
2010 Perez CJ, Jaubert J, Gueacute JL, Barnhart KF, Ross-Inta CM, Quintanilla VC, Aubin I, Brandon JL, Otto NW, DiGiovanni J, Gimenez-Conti I, Giulivi C, Kusewitt DF, Conti CJ, Benavides F. Two hypomorphic alleles of mouse Ass1 as a new animal model of citrullinemia type I and other hyperammonemic syndromes American Journal of Pathology. 177: 1958-1968. PMID 20724589 DOI: 10.2353/Ajpath.2010.100118  1
2010 Kiguchi K, Kitamura T, Moore T, Rumi M, Chang HC, Treece D, Ruffino L, Connolly K, DiGiovanni J. Dual inhibition of both the epidermal growth factor receptor and erbB2 effectively inhibits the promotion of skin tumors during two-stage carcinogenesis. Cancer Prevention Research (Philadelphia, Pa.). 3: 940-52. PMID 20682802 DOI: 10.1158/1940-6207.Capr-10-0010  1
2010 Kim DJ, Tremblay ML, DiGiovanni J. Protein Tyrosine Phosphatases, TC-PTP, SHP1, and SHP2, Cooperate in Rapid Dephosphorylation of Stat3 in Keratinocytes Following UVB Irradiation Plos One. 5. PMID 20421975 DOI: 10.1371/Journal.Pone.0010290  1
2010 Clifford JL, DiGiovanni J. The promise of natural products for blocking early events in skin carcinogenesis. Cancer Prevention Research (Philadelphia, Pa.). 3: 132-5. PMID 20103730 DOI: 10.1158/1940-6207.Capr-09-0267  1
2010 Yasgar A, Shultz J, Zhou W, Wang H, Huang F, Murphy N, Abel EL, DiGiovanni J, Inglese J, Simeonov A. A high-throughput 1,536-well luminescence assay for glutathione S-transferase activity. Assay and Drug Development Technologies. 8: 200-11. PMID 20085484 DOI: 10.1089/Adt.2009.0248  1
2010 Moore T, Beltran L, Carbajal S, Jiang G, Bhatt T, Hursting S, DiGiovanni J. Abstract 966: Dietary energy balance modulates IGF-1R and EGFR signaling and crosstalk during tumor promotion Cancer Research. 70: 966-966. DOI: 10.1158/1538-7445.Am10-966  1
2010 Blando JM, Moore T, Beltran L, Jiang G, Strom S, Hursting S, DiGiovanni J. Abstract 943: Obesity, P13k/Akt/mTOR signaling and prostate carcinogenesis in HiMyc mice Cancer Research. 70: 943-943. DOI: 10.1158/1538-7445.Am10-943  1
2010 Rao D, Carbajal S, Kiguchi K, DiGiovanni J. Abstract 4300: Constitutive activation of Stat3 increases hair follicle progenitor population at the expense of bulge region keratinocyte stem cells Cancer Research. 70: 4300-4300. DOI: 10.1158/1538-7445.Am10-4300  1
2010 Abel EL, Angel JM, Riggs PK, Langfield L, Jiang A, Carbajal S, Lo H, Person M, Awasthi Y, Wang L, Strom S, Wei Q, DiGiovanni J. Abstract 4210: Gsta4 modifies susceptibility to skin tumor development in mice and humans Cancer Research. 70: 4210-4210. DOI: 10.1158/1538-7445.Am10-4210  1
2010 Kitamura T, Connolly K, Lueckgen A, DiGiovanni J, Kiguchi K. Abstract 4176: Bile acid-promoted esophageal and forestomach carcinomas in BK5.erbB2 mice Cancer Research. 70: 4176-4176. DOI: 10.1158/1538-7445.Am10-4176  1
2010 Kim DJ, Tremblay ML, DiGiovanni J. Abstract 4007: Cooperative regulation of Stat3 signaling by TC-PTP, SHP1, and SHP2 in keratinocytes following UVB irradiation Cancer Research. 70: 4007-4007. DOI: 10.1158/1538-7445.Am10-4007  1
2010 Sandifer LA, Moore T, Rho O, DiGiovanni J. Abstract 2481: Rapamycin is a potent inhibitor of skin tumor promotion by TPA Cancer Research. 70: 2481-2481. DOI: 10.1158/1538-7445.Am10-2481  1
2010 Bozeman R, Abel E, DiGiovanni J. Abstract 2480: Role of Stat1 in epithelial carcinogenesis Cancer Research. 70: 2480-2480. DOI: 10.1158/1538-7445.Am10-2480  1
2010 Rho O, Jiang G, Sandifer A, DiGiovanni J. Abstract 2475: Effect of mTOR inhibition by rapamycin on promotion of skin tumors in BK5. Aktwt transgenic mice Cancer Research. 70: 2475-2475. DOI: 10.1158/1538-7445.Am10-2475  1
2010 Nagaraj NK, DiGiovanni JJ, Ries DT. The relative contribution of adaptation and temporal integration in forward masking Proceedings of Meetings On Acoustics. 9. DOI: 10.1121/1.3385247  1
2010 DiGiovanni JJ, Rutledge JC, Umble CS, Mester AP. Performance of phonemically-targeted processing in conjunction with compression processing with spectral enhancement Proceedings of Meetings On Acoustics. 9. DOI: 10.1121/1.3384114  1
2009 Syed Z, Cheepala SB, Gill JN, Stein J, Nathan C, Digiovanni J, Batra V, Adegboyega P, Kleiner HE, Clifford JL. All-trans retinoic acid suppresses Stat3 signaling during skin carcinogenesis. Cancer Prevention Research (Philadelphia, Pa.). 2: 903-11. PMID 19789299 DOI: 10.1158/1940-6207.Capr-09-0041  1
2009 Moral M, Segrelles C, Martínez-Cruz AB, Lorz C, Santos M, García-Escudero R, Lu J, Buitrago A, Costa C, Saiz C, Ariza JM, Dueñas M, Rodriguez-Peralto JL, Martinez-Tello FJ, Rodriguez-Pinilla M, ... ... Digiovanni J, et al. Transgenic mice expressing constitutively active Akt in oral epithelium validate KLFA as a potential biomarker of head and neck squamous cell carcinoma. In Vivo (Athens, Greece). 23: 653-60. PMID 19779097  1
2009 Kim DJ, Kataoka K, Rao D, Kiguchi K, Cotsarelis G, Digiovanni J. Targeted disruption of stat3 reveals a major role for follicular stem cells in skin tumor initiation. Cancer Research. 69: 7587-94. PMID 19738054 DOI: 10.1158/0008-5472.Can-09-1180  1
2009 Abel EL, Angel JM, Kiguchi K, DiGiovanni J. Multi-stage chemical carcinogenesis in mouse skin: fundamentals and applications. Nature Protocols. 4: 1350-62. PMID 19713956 DOI: 10.1038/Nprot.2009.120  1
2009 Brandon JL, Conti CJ, Goldstein LS, DiGiovanni J, Gimenez-Conti IB. Carcinogenic effects of MGP-7 and B[a]P on the hamster cheek pouch. Toxicologic Pathology. 37: 733-40. PMID 19679887 DOI: 10.1177/0192623309344203  1
2009 Ries DT, DiGiovanni JJ. Effects of recurrent tonal information on auditory working memory for pitch. Hearing Research. 255: 14-21. PMID 19435599 DOI: 10.1016/J.Heares.2009.05.002  1
2009 Hursting SD, Perkins SN, Lavigne JA, Beltran L, Haines DC, Hill HL, Alvord WG, Barrett JC, DiGiovanni J. Urothelial overexpression of insulin-like growth factor-1 increases susceptibility to p-cresidine-induced bladder carcinogenesis in transgenic mice. Molecular Carcinogenesis. 48: 671-7. PMID 19415693 DOI: 10.1002/Mc.20548  1
2009 Kim DJ, Kataoka K, Sano S, Connolly K, Kiguchi K, DiGiovanni J. Targeted disruption of Bcl-xL in mouse keratinocytes inhibits both UVB- and chemically induced skin carcinogenesis. Molecular Carcinogenesis. 48: 873-85. PMID 19309000 DOI: 10.1002/Mc.20527  1
2009 Chen X, Schneider-Broussard R, Hollowell D, McArthur M, Jeter CR, Benavides F, DiGiovanni J, Tang DG. Abnormal differentiation, hyperplasia and embryonic/perinatal lethality in BK5-T/t transgenic mice. Differentiation; Research in Biological Diversity. 77: 324-34. PMID 19272531 DOI: 10.1016/J.Diff.2008.10.011  1
2009 Moral M, Segrelles C, Lara MF, Martínez-Cruz AB, Lorz C, Santos M, García-Escudero R, Lu J, Kiguchi K, Buitrago A, Costa C, Saiz C, Rodriguez-Peralto JL, Martinez-Tello FJ, Rodriguez-Pinilla M, ... ... DiGiovanni J, et al. Akt activation synergizes with Trp53 loss in oral epithelium to produce a novel mouse model for head and neck squamous cell carcinoma. Cancer Research. 69: 1099-108. PMID 19176372 DOI: 10.1158/0008-5472.Can-08-3240  1
2009 Kim DJ, Angel JM, Sano S, DiGiovanni J. Constitutive activation and targeted disruption of signal transducer and activator of transcription 3 (Stat3) in mouse epidermis reveal its critical role in UVB-induced skin carcinogenesis. Oncogene. 28: 950-60. PMID 19137019 DOI: 10.1038/Onc.2008.453  1
2008 Ries DT, Schlauch RS, DiGiovanni JJ. The role of temporal-masking patterns in the determination of subjective duration and loudness for ramped and damped sounds. The Journal of the Acoustical Society of America. 124: 3772-83. PMID 19206803 DOI: 10.1121/1.2999342  1
2008 Moore T, Beltran L, Carbajal S, Strom S, Traag J, Hursting SD, DiGiovanni J. Dietary energy balance modulates signaling through the Akt/mammalian target of rapamycin pathways in multiple epithelial tissues. Cancer Prevention Research (Philadelphia, Pa.). 1: 65-76. PMID 19138937 DOI: 10.1158/1940-6207.Capr-08-0022  1
2008 Wang G, Carbajal S, Vijg J, DiGiovanni J, Vasquez KM. DNA structure-induced genomic instability in vivo. Journal of the National Cancer Institute. 100: 1815-7. PMID 19066276 DOI: 10.1093/Jnci/Djn385  1
2008 Liu B, Xia X, Zhu F, Park E, Carbajal S, Kiguchi K, DiGiovanni J, Fischer SM, Hu Y. IKKalpha is required to maintain skin homeostasis and prevent skin cancer. Cancer Cell. 14: 212-25. PMID 18772111 DOI: 10.1016/J.Ccr.2008.07.017  1
2008 Kleiner HE, Xia X, Sonoda J, Zhang J, Pontius E, Abey J, Evans RM, Moore DD, DiGiovanni J. Effects of naturally occurring coumarins on hepatic drug-metabolizing enzymes in mice. Toxicology and Applied Pharmacology. 232: 337-50. PMID 18692084 DOI: 10.1016/J.Taap.2008.07.004  1
2008 de Ostrovich KK, Lambertz I, Colby JK, Tian J, Rundhaug JE, Johnston D, Conti CJ, DiGiovanni J, Fuchs-Young R. Paracrine overexpression of insulin-like growth factor-1 enhances mammary tumorigenesis in vivo. The American Journal of Pathology. 173: 824-34. PMID 18688034 DOI: 10.2353/Ajpath.2008.071005  1
2008 Moore T, Carbajal S, Beltran L, Perkins SN, Yakar S, Leroith D, Hursting SD, Digiovanni J. Reduced susceptibility to two-stage skin carcinogenesis in mice with low circulating insulin-like growth factor I levels. Cancer Research. 68: 3680-8. PMID 18483250 DOI: 10.1158/0008-5472.Can-07-6271  1
2008 Kataoka K, Kim DJ, Carbajal S, Clifford JL, DiGiovanni J. Stage-specific disruption of Stat3 demonstrates a direct requirement during both the initiation and promotion stages of mouse skin tumorigenesis. Carcinogenesis. 29: 1108-14. PMID 18453544 DOI: 10.1093/Carcin/Bgn061  1
2008 Strom SS, Yamamura Y, Forman MR, Pettaway CA, Barrera SL, DiGiovanni J. Saturated fat intake predicts biochemical failure after prostatectomy. International Journal of Cancer. Journal International Du Cancer. 122: 2581-5. PMID 18324626 DOI: 10.1002/Ijc.23414  1
2008 Segrelles C, Moral M, Lorz C, Santos M, Lu J, Cascallana JL, Lara MF, Carbajal S, Martínez-Cruz AB, García-Escudero R, Beltran L, Segovia JC, Bravo A, DiGiovanni J, Paramio JM. Constitutively active Akt induces ectodermal defects and impaired bone morphogenetic protein signaling. Molecular Biology of the Cell. 19: 137-49. PMID 17959825 DOI: 10.1091/Mbc.E07-08-0764  1
2008 Chan KS, Sano S, Kataoka K, Abel E, Carbajal S, Beltran L, Clifford J, Peavey M, Shen J, Digiovanni J. Forced expression of a constitutively active form of Stat3 in mouse epidermis enhances malignant progression of skin tumors induced by two-stage carcinogenesis. Oncogene. 27: 1087-94. PMID 17700521 DOI: 10.1038/Sj.Onc.1210726  1
2008 Sano S, Chan KS, DiGiovanni J. Impact of Stat3 activation upon skin biology: a dichotomy of its role between homeostasis and diseases. Journal of Dermatological Science. 50: 1-14. PMID 17601706 DOI: 10.1016/J.Jdermsci.2007.05.016  1
2008 Moore T, Carbajal S, Jiang A, Beltran L, Hursting S, DiGiovanni J. Abstract 1604: Dietary energy balance modulates multistage epithelial carcinogenesis in mouse skin Prevention and Research. DOI: 10.1158/1538-7445.Am2008-1604  1
2008 Digiovanni JJ, Stover AK. The role of consonant duration and amplitude processing on speech intelligibility in noise Proceedings of Meetings On Acoustics. 4. DOI: 10.1121/1.2935734  1
2007 Lu J, Rho O, Wilker E, Beltran L, Digiovanni J. Activation of epidermal akt by diverse mouse skin tumor promoters. Molecular Cancer Research : McR. 5: 1342-52. PMID 18171992 DOI: 10.1158/1541-7786.Mcr-07-0115  1
2007 DiGiovanni JJ, Repka JN. Response method in audiometry. American Journal of Audiology. 16: 145-8. PMID 18056882 DOI: 10.1044/1059-0889(2007/018)  1
2007 Segrelles C, Lu J, Hammann B, Santos M, Moral M, Cascallana JL, Lara MF, Rho O, Carbajal S, Traag J, Beltrán L, Martínez-Cruz AB, García-Escudero R, Lorz C, Ruiz S, ... ... DiGiovanni J, et al. Deregulated activity of Akt in epithelial basal cells induces spontaneous tumors and heightened sensitivity to skin carcinogenesis. Cancer Research. 67: 10879-88. PMID 18006833 DOI: 10.1158/0008-5472.Can-07-2564  1
2007 DiGiovanni JJ, Nair P. Response growth using a low-frequency suppressor. Hearing Research. 234: 15-20. PMID 17923348 DOI: 10.1016/J.Heares.2007.08.008  1
2007 Kim DJ, Chan KS, Sano S, Digiovanni J. Signal transducer and activator of transcription 3 (Stat3) in epithelial carcinogenesis. Molecular Carcinogenesis. 46: 725-31. PMID 17610223 DOI: 10.1002/Mc.20342  1
2007 Kiguchi K, Ruffino L, Kawamoto T, Franco E, Kurakata S, Fujiwara K, Hanai M, Rumi M, DiGiovanni J. Therapeutic effect of CS-706, a specific cyclooxygenase-2 inhibitor, on gallbladder carcinoma in BK5.ErbB-2 mice. Molecular Cancer Therapeutics. 6: 1709-17. PMID 17575102 DOI: 10.1158/1535-7163.Mct-07-0015  1
2007 Ries DT, DiGiovanni JJ. Release from interference in auditory working memory for pitch. Hearing Research. 230: 64-72. PMID 17574355 DOI: 10.1016/J.Heares.2007.04.003  1
2007 DiGiovanni JJ, Ries DT. Stapedial reflex and ears with high static acoustic admittance. American Journal of Audiology. 16: 68-74. PMID 17562756 DOI: 10.1044/1059-0889(2007/006)  1
2007 Lee S, Chari NS, Kim HW, Wang X, Roop DR, Cho SH, DiGiovanni J, McDonnell TJ. Cooperation of Ha-ras and Bcl-2 during multistep skin carcinogenesis. Molecular Carcinogenesis. 46: 949-57. PMID 17538944 DOI: 10.1002/Mc.20334  1
2007 Wu Q, Kiguchi K, Kawamoto T, Ajiki T, Traag J, Carbajal S, Ruffino L, Thames H, Wistuba I, Thomas M, Vasquez KM, DiGiovanni J. Therapeutic effect of rapamycin on gallbladder cancer in a transgenic mouse model. Cancer Research. 67: 3794-800. PMID 17440093 DOI: 10.1158/0008-5472.Can-06-3214  1
2007 Shen J, Riggs PK, Hensley SC, Schroeder LJ, Traner AR, Kochan KJ, Person MD, DiGiovanni J. Differential expression of multiple anti-apoptotic proteins in epidermis of IGF-1 transgenic mice as revealed by 2-dimensional gel electrophoresis/mass spectrometry analysis. Molecular Carcinogenesis. 46: 331-40. PMID 17330866 DOI: 10.1002/Mc.20256  1
2007 Wu Q, Gaddis SS, MacLeod MC, Walborg EF, Thames HD, DiGiovanni J, Vasquez KM. High-affinity triplex-forming oligonucleotide target sequences in mammalian genomes. Molecular Carcinogenesis. 46: 15-23. PMID 17013831 DOI: 10.1002/Mc.20261  1
2007 Lionikas A, Angel JM, DiGiovanni J, Vogler GP, Blizard DA. Searching for Genes Affecting Skeletal Muscle: 569 Medicine and Science in Sports and Exercise. 39. DOI: 10.1249/01.Mss.0000272928.77134.87  1
2007 DiGiovanni JJ, Schlauch RS. Mechanisms responsible for differences in perceived duration for rising-intensity and falling-intensity sounds Ecological Psychology. 19: 239-264. DOI: 10.1080/10407410701432329  1
2007 Correll P, Digiovanni J. Wi-Fi range: Impact on data rates, coverage, and capacity Emerging Technologies in Wireless Lans: Theory, Design, and Deployment. 535-550. DOI: 10.1017/CBO9780511611421.027  1
2006 DiGiovanni JJ, Nair P. Auditory filters and the benefit measured from spectral enhancement. The Journal of the Acoustical Society of America. 120: 1529-38. PMID 17004474 DOI: 10.1121/1.2221554  1
2006 DiGiovanni J, Hess S. Role playing. Busy medical staff input was invaluable to Mid-Atlantic Hospital in reengineering access to information. Healthcare Informatics : the Business Magazine For Information and Communication Systems. 23: 66, 68. PMID 17001967  1
2006 Digiovanni JJ, Nair P. Spontaneous recovery of sudden sensorineural hearing loss: possible association with autoimmune disorders. Journal of the American Academy of Audiology. 17: 498-505. PMID 16927514 DOI: 10.3766/Jaaa.17.7.5  1
2006 Gaddis SS, Wu Q, Thames HD, DiGiovanni J, Walborg EF, MacLeod MC, Vasquez KM. A web-based search engine for triplex-forming oligonucleotide target sequences. Oligonucleotides. 16: 196-201. PMID 16764543 DOI: 10.1089/Oli.2006.16.196  1
2006 Yin W, Cheepala S, Roberts JN, Syson-Chan K, DiGiovanni J, Clifford JL. Active Stat3 is required for survival of human squamous cell carcinoma cells in serum-free conditions. Molecular Cancer. 5: 15. PMID 16603078 DOI: 10.1186/1476-4598-5-15  1
2006 He G, Sung YM, Digiovanni J, Fischer SM. Thiazolidinediones inhibit insulin-like growth factor-i-induced activation of p70S6 kinase and suppress insulin-like growth factor-I tumor-promoting activity. Cancer Research. 66: 1873-8. PMID 16452250 DOI: 10.1158/0008-5472.Can-05-3111  1
2005 Wilker E, Lu J, Rho O, Carbajal S, Beltrán L, DiGiovanni J. Role of PI3K/Akt signaling in insulin-like growth factor-1 (IGF-1) skin tumor promotion. Molecular Carcinogenesis. 44: 137-45. PMID 16086373 DOI: 10.1002/Mc.20132  1
2005 Kiguchi K, Ruffino L, Kawamoto T, Ajiki T, Digiovanni J. Chemopreventive and therapeutic efficacy of orally active tyrosine kinase inhibitors in a transgenic mouse model of gallbladder carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 5572-80. PMID 16061875 DOI: 10.1158/1078-0432.Ccr-04-2603  1
2005 Riggs PK, Angel JM, Abel EL, DiGiovanni J. Differential gene expression in epidermis of mice sensitive and resistant to phorbol ester skin tumor promotion. Molecular Carcinogenesis. 44: 122-36. PMID 16044405 DOI: 10.1002/Mc.20127  1
2005 Sano S, Chan KS, Kira M, Kataoka K, Takagi S, Tarutani M, Itami S, Kiguchi K, Yokoi M, Sugasawa K, Mori T, Hanaoka F, Takeda J, DiGiovanni J. Signal transducer and activator of transcription 3 is a key regulator of keratinocyte survival and proliferation following UV irradiation. Cancer Research. 65: 5720-9. PMID 15994947 DOI: 10.1158/0008-5472.Can-04-4359  1
2005 Mammen JS, Kleiner HE, DiGiovanni J, Sutter TR, Strickland PT. Coumarins are competitive inhibitors of cytochrome P450 1B1, with equal potency for allelic variants. Pharmacogenetics and Genomics. 15: 183-8. PMID 15861043 DOI: 10.1097/01213011-200503000-00007  1
2005 Sano S, Chan KS, Carbajal S, Clifford J, Peavey M, Kiguchi K, Itami S, Nickoloff BJ, DiGiovanni J. Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model. Nature Medicine. 11: 43-9. PMID 15592573 DOI: 10.1038/Nm1162  1
2004 Kleiner HE, Vulimiri SV, Hatten WB, Reed MJ, Nebert DW, Jefcoate CR, DiGiovanni J. Role of cytochrome P4501 family members in the metabolic activation of polycyclic aromatic hydrocarbons in mouse epidermis Chemical Research in Toxicology. 17: 1667-1674. PMID 15606143 DOI: 10.1021/Tx049919C  1
2004 Chan KS, Sano S, Kiguchi K, Anders J, Komazawa N, Takeda J, DiGiovanni J. Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis. The Journal of Clinical Investigation. 114: 720-8. PMID 15343391 DOI: 10.1172/Jci21032  1
2004 Matsumoto T, Kiguchi K, Jiang J, Carbajal S, Ruffino L, Beltrán L, Wang XJ, Roop DR, DiGiovanni J. Development of transgenic mice that inducibly express an active form of c-Src in the epidermis. Molecular Carcinogenesis. 40: 189-200. PMID 15264211 DOI: 10.1002/Mc.20027  1
2004 Soliman AS, Vulimiri SV, Kleiner HE, Shen J, Eissa S, Morad M, Taha H, Lukmanji F, Li D, Johnston DA, Lo HH, Lau S, Digiovanni J, Bondy ML. High levels of oxidative DNA damage in lymphocyte DNA of premenopausal breast cancer patients from Egypt. International Journal of Environmental Health Research. 14: 121-34. PMID 15203457 DOI: 10.1080/0960312042000209534  1
2004 Chan KS, Carbajal S, Kiguchi K, Clifford J, Sano S, DiGiovanni J. Epidermal growth factor receptor-mediated activation of Stat3 during multistage skin carcinogenesis. Cancer Research. 64: 2382-9. PMID 15059889 DOI: 10.1158/0008-5472.Can-03-3197  1
2004 Salas TR, Kim J, Vakar-Lopez F, Sabichi AL, Troncoso P, Jenster G, Kikuchi A, Chen SY, Shemshedini L, Suraokar M, Logothetis CJ, DiGiovanni J, Lippman SM, Menter DG. Glycogen synthase kinase-3 beta is involved in the phosphorylation and suppression of androgen receptor activity. The Journal of Biological Chemistry. 279: 19191-200. PMID 14985354 DOI: 10.1074/Jbc.M309560200  1
2003 Soliman AS, Wang X, DiGiovanni J, Eissa S, Morad M, Vulimiri S, Mahgoub KG, Johnston DA, Do KA, Seifeldin IA, Boffetta P, Bondy ML. Serum organochlorine levels and history of lactation in Egypt. Environmental Research. 92: 110-7. PMID 12854690 DOI: 10.1016/S0013-9351(02)00056-7  1
2003 Kleiner HE, Reed MJ, DiGiovanni J. Naturally occurring coumarins inhibit human cytochromes P450 and block benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene DNA adduct formation in MCF-7 cells Chemical Research in Toxicology. 16: 415-422. PMID 12641443 DOI: 10.1021/Tx025636D  1
2003 Liu Z, Wang LE, Strom SS, Spitz MR, Babaian RJ, DiGiovanni J, Wei Q. Overexpression of hMTH in peripheral lymphocytes and risk of prostate cancer: a case-control analysis. Molecular Carcinogenesis. 36: 123-9. PMID 12619034 DOI: 10.1002/Mc.10108  1
2003 Miyahara N, Shoda J, Ueda T, Kawamoto T, Tanaka N, Irimura T, Akimoto Y, Kawakami H, Digiovanni J, Kiguchi K. Up-regulation of Muc4 and its complex formation with ErbB2 in murine gallbladder carcinoma—a potential mechanism for gallbladder carcinogenesis and/or tumor growth Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)83060-3  1
2003 DiGiovanni J. Changes to Molecular Carcinogenesis Molecular Carcinogenesis. 37: 121-121. DOI: 10.1002/Mc.10133  0.01
2002 Matsumoto T, Jiang J, Kiguchi K, Carbajal S, Rho O, Gimenez-Conti I, Beltran LM, DiGiovanni J. Overexpression of a constitutively active form of c-src in skin epidermis increases sensitivity to tumor promotion by 12-O-tetradecanoylphorbol-13-acetate. Molecular Carcinogenesis. 33: 146-155. PMID 11870880 DOI: 10.1002/Mc.10030  1
2001 Angel JM, Caballero M, DiGiovanni J. Confirmation of the mapping of a 12-O-tetradecanoylphorbol-13-acetate promotion susceptibility locus, Psl1, to distal mouse chromosome 9. Molecular Carcinogenesis. 32: 169-75. PMID 11746828 DOI: 10.1002/Mc.10010  1
2001 Mason PA, Walters TJ, DiGiovanni J, Beason CW, Jauchem JR, Dick EJ, Mahajan K, Dusch SJ, Shields BA, Merritt JH, Murphy MR, Ryan KL. Lack of effect of 94 GHz radio frequency radiation exposure in an animal model of skin carcinogenesis. Carcinogenesis. 22: 1701-8. PMID 11577012 DOI: 10.1093/Carcin/22.10.1701  1
2001 Li D, Zhang W, Zhu J, Chang P, Sahin A, Singletary E, Bondy M, Hazra T, Mitra S, Lau SS, Shen J, DiGiovanni J. Oxidative DNA damage and 8-hydroxy-2-deoxyguanosine DNA glycosylase/apurinic lyase in human breast cancer. Molecular Carcinogenesis. 31: 214-23. PMID 11536371 DOI: 10.1002/Mc.1056  1
2001 Kleiner HE, Vulimiri SV, Miller L, Johnson WH, Whitman CP, DiGiovanni J. Oral administration of naturally occurring coumarins leads to altered phase I and II enzyme activities and reduced DNA adduct formation by polycyclic aromatic hydrocarbons in various tissues of SENCAR mice Carcinogenesis. 22: 73-82. PMID 11159744 DOI: 10.1093/Carcin/22.1.73  1
2000 Kiguchi K, Bol D, Carbajal S, Beltrán L, Moats S, Chan K, Jorcano J, DiGiovanni J. Constitutive expression of erbB2 in epidermis of transgenic mice results in epidermal hyperproliferation and spontaneous skin tumor development Oncogene. 19: 4243-4254. PMID 10980598 DOI: 10.1038/Sj.Onc.1203778  1
2000 Benavides F, Stern MC, Glasscock E, DiGiovanni J, Coghlan LG, Conti CJ. Microsatellite DNA variants between the inbred SENCAR mouse strains. Molecular Carcinogenesis. 28: 191-5. PMID 10972988 DOI: 10.1002/1098-2744(200008)28:4<191::Aid-Mc1>3.0.Co;2-K  1
2000 Firozi PF, Vulimiri SV, Rajaniemi H, Hemminki K, Dragan Y, Pitot HC, DiGiovanni J, Zhu YH, Li D. Characterization of the major DNA adducts in the liver of rats chronically exposed to tamoxifen for 18 months. Chemico-Biological Interactions. 126: 33-43. PMID 10826652 DOI: 10.1016/S0009-2797(00)00151-4  1
2000 Riggs PK, Rho O, DiGiovanni J. Alteration of Egr-1 mRNA during multistage carcinogenesis in mouse skin. Molecular Carcinogenesis. 27: 247-251. PMID 10747287 DOI: 10.1002/(Sici)1098-2744(200004)27:4<247::Aid-Mc1>3.0.Co;2-4  1
2000 DiGiovanni J, Kiguchi K, Frijhoff A, Wilker E, Bol DK, Beltrán L, Moats S, Ramirez A, Jorcano J, Conti C. Deregulated expression of insulin-like growth factor 1 in prostate epithelium leads to neoplasia in transgenic mice Proceedings of the National Academy of Sciences of the United States of America. 97: 3455-3460. PMID 10737798 DOI: 10.1073/Pnas.97.7.3455  1
2000 Angel JM, Popova N, Lanko N, Turusov VS, DiGiovanni J. A locus that influences susceptibility to 1, 2-dimethylhydrazine-induced colon tumors maps to the distal end of mouse chromosome 3. Molecular Carcinogenesis. 27: 47-54. PMID 10642436 DOI: 10.1002/(Sici)1098-2744(200001)27:1<47::Aid-Mc7>3.0.Co;2-7  1
1999 Angel JM, DiGiovanni J. Genetics of skin tumor promotion. Progress in Experimental Tumor Research. 35: 143-57. PMID 10377758 DOI: 10.1159/000062010  1
1999 Wilker E, Bol D, Kiguchi K, Rupp T, Beltran LM, DiGiovanni J. Enhancement of susceptibility to diverse skin tumor promoters by activation of the insulin-like growth factor-1 receptor in the epidermis of transgenic mice. Molecular Carcinogenesis. 25: 122-131. PMID 10365914 DOI: 10.1002/(Sici)1098-2744(199906)25:2<122::Aid-Mc7>3.0.Co;2-8  1
1999 DiGiovanni J, Johnston DA, Rupp T, Sasser LB, Anderson LE, Morris JE, Miller DL, Kavet R, Walborg EF. Lack of effect of a 60 Hz magnetic field on biomarkers of tumor promotion in the skin of SENCAR mice. Carcinogenesis. 20: 685-9. PMID 10223200 DOI: 10.1093/Carcin/20.4.685  1
1999 Vulimiri SV, Baer-Dubowska W, Harvey RG, Zhang JT, DiGiovanni J. Analysis of highly polar DNA adducts formed in SENCAR mouse epidermis following topical application of dibenz[a,j]anthracene. Chemical Research in Toxicology. 12: 60-7. PMID 9894019 DOI: 10.1021/Tx980139B  1
1999 Hursting S, Liebert M, Baum L, Shen J, Conti C, DiGiovanni J, Fischer S, French J. Prevention Of P-Cresidine-Induced Bladder Carcinogenesis In P53-Deficient Mice The Journal of Urology. 114. DOI: 10.1097/00005392-199904010-00457  1
1999 Slaga TJ, Barrett JC, DiGiovanni J. Introducing emerging technologies Molecular Carcinogenesis. 25: 85-85. DOI: 10.1002/(Sici)1098-2744(199906)25:2<85::Aid-Mc1>3.0.Co;2-8  1
1998 Kiguchi K, Kagehara M, Higo R, Iwamori M, DiGiovanni J. Alterations in Cholesterol Sulfate and its Biosynthetic Enzyme During Multistage Carcinogenesis in Mouse Skin Journal of Investigative Dermatology. 111: 973-981. PMID 9856804 DOI: 10.1046/J.1523-1747.1998.00404.X  1
1998 Sasser LB, Anderson LE, Morris JE, Miller DL, Walborg EF, Kavet R, Johnston DA, DiGiovanni J. Lack of a co-promoting effect of a 60 Hz magnetic field on skin tumorigenesis in SENCAR mice. Carcinogenesis. 19: 1617-21. PMID 9771933 DOI: 10.1093/Carcin/19.9.1617  1
1998 Kiguchi K, Beltran LM, Rupp T, DiGiovanni J. Altered expression of epidermal growth factor receptor ligands in tumor promoter-treated mouse epidermis and in primary mouse skin tumors induced by an initiation-promotion protocol. Molecular Carcinogenesis. 22: 73-83. PMID 9655251 DOI: 10.1002/(Sici)1098-2744(199806)22:2<73::Aid-Mc2>3.0.Co;2-L  1
1998 Bol D, Kiguchi K, Beltran LM, Rupp T, Moats S, Gimenez-Conti I, Jorcano J, DiGiovanni J. Severe follicular hyperplasia and spontaneous papilloma formation in transgenic mice expressing the neu oncogene under the control of the bovine keratin 5 promoter. Molecular Carcinogenesis. 21: 2-12. PMID 9473766 DOI: 10.1002/(Sici)1098-2744(199801)21:1<2::Aid-Mc2>3.0.Co;2-R  1
1998 Stern MC, Gimenez-Conti IB, Budunova I, Coghlan L, Fischer SM, DiGiovanni J, Slaga TJ, Conti CJ. Analysis of two inbred strains of mice derived from the SENCAR stock with different susceptibility to skin tumor progression Carcinogenesis. 19: 125-132. PMID 9472703 DOI: 10.1093/Carcin/19.1.125  1
1998 Kiguchi K, Beltran L, Bol D, DiGiovanni J. Epidermal hyperplasia and skin tumors induced by targeted expression of ERBB-2 in transgenic mice Journal of Dermatological Science. 16. DOI: 10.1016/S0923-1811(98)83276-3  1
1998 Slaga TJ, DiGiovanni J, Klein-Szanto AJP. Eleventh International Conference on Carcinogenesis and Risk Assessment environmental skin carcinogenesis: UV- and chemically induced cancer implications for risk assessment Molecular Carcinogenesis. 23: 131-131. DOI: 10.1002/(Sici)1098-2744(199811)23:3<131::Aid-Mc1>3.0.Co;2-5  1
1997 Angel JM, Beltrán L, Minda K, Rupp T, DiGiovanni J. Association of a murine chromosome 9 locus (Psl1) with susceptibility to mouse skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate. Molecular Carcinogenesis. 20: 162-7. PMID 9364205 DOI: 10.1002/(Sici)1098-2744(199710)20:2<162::Aid-Mc2>3.0.Co;2-P  1
1997 Rundhaug JE, Gimenez-Conti I, Stern MC, Budunova IV, Kiguchi K, Bol DK, Coghlan LG, Conti CJ, DiGiovanni J, Fischer SM, Winberg LD, Slaga TJ. Changes in protein expression during multistage mouse skin carcinogenesis Molecular Carcinogenesis. 20: 125-136. PMID 9328443 DOI: 10.1002/(Sici)1098-2744(199709)20:1<125::Aid-Mc14>3.0.Co;2-3  1
1997 Cai Y, Kleiner H, Johnston D, Dubowski A, Bostic S, Ivie W, DiGiovanni J. Effect of naturally occurring coumarins on the formation of epidermal DNA adducts and skin tumors induced by benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in SENCAR mice. Carcinogenesis. 18: 1521-7. PMID 9276625 DOI: 10.1093/Carcin/18.8.1521  1
1997 Xian W, Rosenberg MP, DiGiovanni J. Activation of erbB2 and c-src in phorbol ester-treated mouse epidermis: possible role in mouse skin tumor promotion. Oncogene. 14: 1435-1444. PMID 9136987 DOI: 10.1038/Sj.Onc.1200980  0.01
1997 Bol DK, Kiguchi K, Gimenez-Conti I, Rupp T, DiGiovanni J. Overexpression of Insulin-Like Growth factor-1 Induces Hyperplasia, Dermal Abnormalities, and Spontaneous Tumor Formation in Transgenic Mice Oncogene. 14: 1725-1734. PMID 9135074 DOI: 10.1038/Sj.Onc.1201011  1
1997 Kiguchi K, Beltran LM, Dubowski A, DiGiovanni J. Analysis of the ability of 12-O-tetradecanoylphorbol-13-acetate to induce epidermal hyperplasia, transforming growth factor-α, and skin tumor promotion in wa-1 mice Journal of Investigative Dermatology. 108: 784-791. PMID 9129233 DOI: 10.1111/1523-1747.Ep12292237  1
1997 Baer-Dubowska W, Vulimiri SV, Harvey RG, Cortez C, DiGiovanni J. Analysis of 7-methylbenz[a]anthracene-DNA adducts formed in SENCAR mouse epidermis by 32P-postlabeling. Carcinogenesis. 18: 523-9. PMID 9067552 DOI: 10.1093/Carcin/18.3.523  1
1996 Rho O, Bol DK, You J, Beltrán L, Rupp T, DiGiovanni J. Altered expression of insulin‐like growth factor I and its receptor during multistage carcinogenesis in mouse skin Molecular Carcinogenesis. 17: 62-69. PMID 8890954 DOI: 10.1002/(Sici)1098-2744(199610)17:2<62::Aid-Mc2>3.0.Co;2-V  1
1996 Baer-Dubowska W, Nair RV, Dubowski A, Harvey RG, Cortez C, DiGiovanni J. The effect of fluoro substituents on reactivity of 7-methylbenz[a]anthracene diol epoxides. Chemical Research in Toxicology. 9: 722-8. PMID 8831816 DOI: 10.1021/Tx950207J  1
1996 Min Z, Gill RD, Cortez C, Harvey RG, Loechler EL, DiGiovanni J. Targeted A --> T and G --> T mutations induced by site-specific deoxyadenosine and deoxyguanosine adducts, respectively, from the (+)-anti-diol epoxide of dibenz[a,j]anthracene in M13mp7L2. Biochemistry. 35: 4128-38. PMID 8672448 DOI: 10.1021/Bi952746T  1
1995 Baer-Dubowska W, Nair RV, Cortez C, Harvey RG, DiGiovanni J. Covalent DNA adducts formed in mouse epidermis from dibenz[a,j]anthracene: evidence for the formation of polar adducts. Chemical Research in Toxicology. 8: 292-301. PMID 7766814 DOI: 10.1021/Tx00044A015  1
1995 Kiguchi K, Beltrán LM, You J, Rho O, DiGiovanni J. Elevation of transforming growth factor-alpha mRNA and protein expression by diverse tumor promoters in SENCAR mouse epidermis. Molecular Carcinogenesis. 12: 225-35. PMID 7727044 DOI: 10.1002/Mc.2940120407  1
1994 Wang XJ, Warren BS, Rupp T, Beltrán LM, DiGiovanni J. Loss of mouse epidermal protein kinase C isozyme activities following treatment with phorbol ester and non-phorbol ester tumor promoters. Carcinogenesis. 15: 2795-803. PMID 8001237 DOI: 10.1093/Carcin/15.12.2795  0.01
1994 Rho O, Beltrán LM, Gimenez-Conti IB, DiGiovanni J. Altered expression of the epidermal growth factor receptor and transforming growth factor-alpha during multistage skin carcinogenesis in SENCAR mice. Molecular Carcinogenesis. 11: 19-28. PMID 7916986 DOI: 10.1002/Mc.2940110105  1
1993 Imamoto A, Wang XJ, Fujiki H, Walker SE, Beltrán LM, DiGiovanni J. Comparison of 12-O-tetradecanoylphorbol-13-acetate and teleocidin for induction of epidermal hyperplasia, activation of epidermal PKC isozymes and skin tumor promotion in SENCAR and C57BL/6 mice. Carcinogenesis. 14: 719-24. PMID 8472338 DOI: 10.1093/Carcin/14.4.719  0.01
1993 DiGiovanni J, bhatt TS, walker SE. C57BL/6 mice are resistant to tumor promotion by full thickness skin wounding. Carcinogenesis. 14: 319-321. PMID 8435875 DOI: 10.1093/Carcin/14.2.319  0.01
1993 Wang XJ, Warren BS, Beltrán LM, Fosmire SP, DiGiovanni J. Further identification of protein kinase C isozymes in mouse epidermis. Journal of Cancer Research and Clinical Oncology. 119: 279-87. PMID 8382706 DOI: 10.1007/Bf01212726  0.01
1993 Gill RD, Min Z, Cortez C, Harvey RG, Loechler EL, DiGiovanni J. Construction of Escherichia coli vectors containing deoxyadenosine and deoxyguanosine adducts from (+)-anti-dibenz[a,j]anthracene diol epoxide at a defined site. Chemical Research in Toxicology. 6: 681-9. PMID 8292747 DOI: 10.1021/Tx00035A014  1
1993 DiGiovanni J, Beltrán L, Rupp A, Harvey RG, Gill RD. Further analysis of c-Ha-ras mutations in papillomas initiated by several polycyclic aromatic hydrocarbons and papillomas from uninitiated, promoter-treated skin in SENCAR mice. Molecular Carcinogenesis. 8: 272-9. PMID 8280375 DOI: 10.1002/Mc.2940080410  1
1993 Battalora MJ, Kruszewski FH, DiGiovanni J. Inhibition of chrysarobin skin tumor promotion in SENCAR mice by antioxidants. Carcinogenesis. 14: 2507-2512. PMID 8269619 DOI: 10.1093/Carcin/14.12.2507  0.01
1993 Gill RD, Rodriguez H, Cortez C, Harvey RG, Loechler EL, DiGiovanni J. Mutagenic specificity of the (+)anti-diol epoxide of dibenz[a,j]anthracene in the supF gene of an Escherichia coli plasmid. Molecular Carcinogenesis. 8: 145-54. PMID 8216733 DOI: 10.1002/Mc.2940080305  1
1992 Imamoto A, Beltrán LM, Fujiki H, Chenicek KJ, DiGiovanni J. Enhanced induction of epidermal ornithine decarboxylase activity in C57BL/6 compared to DBA/2 mice by protein kinase C-activating skin tumor promoters: relevance to genetically mediated differences in promotion susceptibility. Carcinogenesis. 13: 177-82. PMID 1740006 DOI: 10.1093/Carcin/13.2.177  0.01
1992 Nair RV, Walker SE, Sharma PK, Witiak DT, DiGiovanni J. Mouse skin tumor initiating activity of fluorinated derivatives of 1,2,3,4-tetrahydro-7,12-dimethylbenz[a]anthracene. Chemical Research in Toxicology. 5: 153-156. PMID 1643244 DOI: 10.1021/Tx00026A002  0.01
1992 DiGiovanni J. Multistage carcinogenesis in mouse skin Pharmacology & Therapeutics. 54: 63-128. PMID 1528955 DOI: 10.1016/0163-7258(92)90051-Z  0.01
1992 Gill RD, Beltrán L, Nettikumara AN, Harvey RG, Kootstra A, DiGiovanni J. Analysis of point mutations in murine c-Ha-ras of skin tumors initiated with dibenz[a,j]anthracene and derivatives. Molecular Carcinogenesis. 6: 53-9. PMID 1503644 DOI: 10.1002/Mc.2940060109  1
1992 Nair RV, Nettikumara AN, Cortez C, Harvey RG, DiGiovanni J. Comparative metabolism of dibenz[a,j]anthracene and 7-methyldibenz[a,j]anthracene in primary cultures of mouse keratinocytes Chemical Research in Toxicolgy. 5: 532-540. PMID 1391619 DOI: 10.1021/Tx00028A012  1
1992 Bhatt TS, Beltran LM, Walker SE, DiGiovanni J. Induction of epidermal ornithine decarboxylase activity in mouse skin exposed to biogenic silica fibers Carcinogenesis. 13: 617-620. PMID 1315627 DOI: 10.1093/Carcin/13.4.617  1
1991 Imamoto A, Beltrán LM, DiGiovanni J. Evidence for autocrine/paracrine growth stimulation by transforming growth factor-alpha during the process of skin tumor promotion. Molecular Carcinogenesis. 4: 52-60. PMID 2009135 DOI: 10.1002/Mc.2940040109  0.01
1991 Gill RD, Butterworth BE, Nettikumara AN, DiGiovanni J. Relationship between DNA adduct formation and unscheduled DNA synthesis (UDS) in cultured mouse epidermal keratinocytes. Environmental and Molecular Mutagenesis. 18: 200-6. PMID 1915314 DOI: 10.1002/Em.2850180307  0.01
1991 Nair RV, Gill RD, Nettikumara AN, Baer-Dubowska W, Cortez C, Harvey RG, DiGiovanni J. Characterization of covalently modified deoxyribonucleosides formed from dibenz[a,j]anthracene in primary cultures of mouse keratinocytes. Chemical Research in Toxicology. 4: 115-22. PMID 1912293 DOI: 10.1021/Tx00019A016  1
1991 DiGiovanni J. Modification of multistage skin carcinogenesis in mice. Progress in Experimental Tumor Research. 33: 192-229. PMID 1902960 DOI: 10.1159/000419252  0.01
1991 Nair RV, Fisher EP, Safe SH, Cortez C, Harvey RG, Digiovanni J. Novel coumarins as potential anticarcinogenic agents Carcinogenesis. 12: 65-69. PMID 1899055 DOI: 10.1093/Carcin/12.1.65  1
1990 Imamoto A, Beltrán LM, DiGiovanni J. Differential mechanism for the inhibition of epidermal growth factor binding to its receptor on mouse keratinocytes by anthrones and phorbol esters. Carcinogenesis. 11: 1543-9. PMID 2401043 DOI: 10.1093/Carcin/11.9.1543  0.01
1990 Hirabayashi N, Warren BS, Wang X‐, Petersen‐Marht S, Beltran LM, Davis MM, Ashendel CL, DiGiovanni J. Partial characterization of epidermal protein kinase C in mice sensitive or resistant to phorbol ester Molecular Carcinogenesis. 3: 171-180. PMID 2372371 DOI: 10.1002/Mc.2940030311  0.01
1990 Kehrer JP, DiGiovanni J. Comparison of lung injury induced in 4 strains of mice by butylated hydroxytoluene Toxicology Letters. 52: 55-61. PMID 2356571 DOI: 10.1016/0378-4274(90)90165-I  1
1990 Monks TJ, Walker SE, Flynn LM, Conti CJ, Digiovanni J. Epidermal ornithine decarboxylase induction and mouse skin tumor promotion by quinones Carcinogenesis. 11: 1795-1801. PMID 2119908 DOI: 10.1093/Carcin/11.10.1795  1
1990 Viaje A, Lu JY, Hopkins NE, Nettikumara AN, DiGiovanni J, Alworth WL, Slaga TJ. Inhibition of the binding of 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene to DNA in mouse skin epidermis by 1-ethynylpyrene. Carcinogenesis. 11: 1139-43. PMID 2115405 DOI: 10.1093/Carcin/11.7.1139  1
1989 Nair RV, Gill RD, Cortez C, Harvey RG, DiGiovanni J. Characterization of DNA adducts derived from (+/- )-trans-3,4-dihydroxy-anti-1,2-epoxy-1,2,3,4- tetrahydrodibenz[a,j]anthracene and (+/- )-7-methyl-trans-3,4-dihydroxy- anti-1,2-epoxy-1,2,3,4-tetrahydrodibenz[a,j]anthracene. Chemical Research in Toxicology. 2: 341-8. PMID 2519825 DOI: 10.1021/Tx00011A012  1
1989 Ewing MW, Conti CJ, Phillips JL, Slaga TJ, DiGiovanni J. Further characterization of skin tumor promotion and progression by mezerein in SENCAR mice. Journal of the National Cancer Institute. 81: 676-82. PMID 2496233 DOI: 10.1093/Jnci/81.9.676  1
1988 DiGiovanni J, Kruszewski FH, Coombs MM, Bhatt TS, Pezeshk A. Structure-activity relationships for epidermal ornithine decarboxylase induction and skin tumor promotion by anthrones. Carcinogenesis. 9: 1437-43. PMID 3402040 DOI: 10.1093/Carcin/9.8.1437  0.01
1988 Harvey RG, Cortez C, Sawyer TW, Digiovanni J. Synthesis of the tumorigenic 3,4-dihydrodiol metabolites of dibenz[a,j]anthracene and 7,14-dimethyldibenz[a,j]anthracene Journal of Medicinal Chemistry. 31: 1308-1312. PMID 3385726 DOI: 10.1021/Jm00402A009  1
1988 Sawyer TW, Gill RD, Smith-Oliver T, Butterworth BE, DiGiovanni J. Measurement of unscheduled DNA synthesis in primary cultures of adult mouse epidermal keratinocytes. Carcinogenesis. 9: 1197-202. PMID 3383338 DOI: 10.1093/Carcin/9.7.1197  0.01
1988 DiGiovanni J, Kruszewski FH, Chenicek KJ. Modulation of chrysarobin skin tumor promotion Carcinogenesis. 9: 1445-1450. PMID 3135955 DOI: 10.1093/Carcin/9.8.1445  0.01
1988 Ewing MW, Crysup SE, Phillips JL, Slaga TJ, DiGiovanni J. Enhancement of mezerein-promoted papilloma formation by treatment with 12-O-tetradecanoylphorbol-13-acetate or mezerein prior to initiation. Carcinogenesis. 9: 405-10. PMID 3125993 DOI: 10.1093/Carcin/9.3.405  1
1988 Harvey RG, Cortez C, Sugiyama T, Ito Y, Sawyer TW, DiGiovanni J. Biologically active dihydrodiol metabolites of polycyclic aromatic hydrocarbons structurally related to the potent carcinogenic hydrocarbon 7,12-dimethylbenz[a]anthracene Journal of Medicinal Chemistry. 31: 154-159. PMID 3121856 DOI: 10.1021/Jm00396A023  1
1983 DiGiovanni J, Boutwell RK. Tumor promoting activity of 1,8-dihydroxy-3-methyl-9-anthrone (chrysarobin) in female SENCAR mice. Carcinogenesis. 4: 281-4. PMID 6831635 DOI: 10.1093/Carcin/4.3.281  0.01
1982 DiGiovanni J, Diamond L, Singer JM, Daniel FB, Witiak DT, Slaga TJ. Tumor-initiating activity of 4-fluoro-7,12-dimethylbenz[a]anthracene and 1,2,3,4-tetrahydro-7,12-dimethylbenz[a]anthracene in female SENCAR mice. Carcinogenesis. 3: 651-5. PMID 6811143 DOI: 10.1093/Carcin/3.6.651  1
1982 DiGiovanni J, Rymer J, Slaga TJ, Boutwell RK. Anticarcinogenic and cocarcinogenic effects of benzo[e]pyrene and dibenz[a,c]anthracene on skin tumor initiation by polycyclic hydrocarbons. Carcinogenesis. 3: 371-5. PMID 6284398 DOI: 10.1093/Carcin/3.4.371  1
1981 Boutwell RK, Hoel MJ, Digiovanni J. The role of anthralin in mouse skin tumour promotion. The British Journal of Dermatology. 105: 68-9. PMID 7284270 DOI: 10.1111/J.1365-2133.1981.Tb01012.X  0.01
1980 DiGiovanni J, Viaje A, Fischer S, Slaga TJ, Boutwell RK. Biotransformation of 7,12-dimethylbenz[alanthracene by mouse epidermal cells in culture. Carcinogenesis. 1: 41-9. PMID 22282979 DOI: 10.1093/Carcin/1.1.41  1
1980 DiGiovanni J, Slaga TJ, Berry DL, Juchau MR. Inhibitory effects of environmental chemicals on polycyclic aromatic hydrocarbon carcinogenesis Carcinogenesis; a Comprehensive Survey. 5: 145-168. PMID 6992995  1
1980 DiGiovanni J, Juchau MR. Biotransformation and bioactivation of 7, 12-dimethylbenz[a]anthracene (7, 12-DMBA). Drug Metabolism Reviews. 11: 61-101. PMID 6775921 DOI: 10.3109/03602538008994022  1
1980 DiGiovanni J, Slaga TJ, Boutwell RK. Comparison of the tumor-initiating activity of 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene in female SENCAR and CS-1 mice. Carcinogenesis. 1: 381-9. PMID 6268318 DOI: 10.1093/Carcin/1.5.381  1
1979 DiGiovanni J, Berry DL, Slaga TJ, Jones AH, Juchau MR. Effects of pretreatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin on the capacity of hepatic and extrahepatic mouse tissues to convert procarcinogens to mutagens for Salmonella typhimurium auxotrophs. Toxicology and Applied Pharmacology. 50: 229-39. PMID 388724 DOI: 10.1016/0041-008X(79)90148-0  1
1979 Juchau MR, DiGiovanni J, Namkung MJ, Jones AH. A comparison of the capacity of fetal and adult liver, lung, and brain to convert polycyclic aromatic hydrocarbons to mutagenic and cytotoxic metabolites in mice and rats. Toxicology and Applied Pharmacology. 49: 171-8. PMID 382440 DOI: 10.1016/0041-008X(79)90288-6  1
1979 Berry DL, Slaga TJ, DiGiovanni J, Juchau MR. Studies with chlorinated dibenzo-p-dioxins, polybrominated biphenyls, and polychlorinated biphenyls in a two-stage system of mouse skin tumorigenesis: potent anticarcinogenic effects Annals of the New York Academy of Sciences. 320: 405-414. PMID 222192 DOI: 10.1111/J.1749-6632.1979.Tb56621.X  1
1979 DiGiovanni J, Romson JR, Linville D, Juchau MR, Slaga TJ. Covalent binding of polycyclic aromatic hydrocarbons to adenine correlates with tumorigenesis in mouse skin Cancer Letters. 7: 39-43. PMID 110439 DOI: 10.1016/S0304-3835(79)80074-9  1
1979 DiGiovanni J, Berry DL, Juchau MR, Slaga TJ. 2,3,7,8-Tetrachlorodibenzo-p-dioxin: Potent anticarcinogenic activity in CD-1 mice Biochemical and Biophysical Research Communications. 86: 577-584. PMID 106852 DOI: 10.1016/0006-291X(79)91752-2  1
1978 Berry DL, DiGiovanni J, Juchau MR, Bracken WM, Gleason GL, Slaga TJ. Lack of tumor-promoting ability of certain environmental chemicals in a two-stage mouse skin tumorigenesis assay Research Communications in Chemical Pathology and Pharmacology. 20: 101-108. PMID 208126  1
1978 Juchau MR, Namkung MJ, Jones AH, DiGiovanni J. Biotransformation and bioactivation of 7,12-dimethylbenz[a]anthracene in human fetal and placental tissues. Analyses of HPLC profiles and studies with Salmonella typhimurium. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 6: 273-81. PMID 26548  1
1977 DiGiovanni J, Fallat LM. Ainhum. Report of a case Journal of the American Podiatric Medical Association. 67: 401-405. PMID 886138 DOI: 10.7547/87507315-67-6-401  0.01
1977 DiGiovanni J, Viaje A, Berry DL, Slaga TJ, Juchau MR. Tumor-initiating ability of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and Arochlor 1254 in the two-stage system of mouse skin carcinogenesis. Bulletin of Environmental Contamination and Toxicology. 18: 552-7. PMID 412534 DOI: 10.1007/Bf01684000  1
1977 Slaga TJ, Thompson S, Berry DL, Digiovanni J, Juchau MR, Viaje A. The effects of benzoflavones on polycyclic hydrocarbon metabolism and skin tumor initiation. Chemico-Biological Interactions. 17: 297-312. PMID 407010 DOI: 10.1016/0009-2797(77)90093-X  1
1977 Berry DL, Slaga TJ, Viaje A, Wilson NM, DiGiovanni J, Juchau MR, Selkirk JK. Effect of trichloropropene oxide on the ability of polyaromatic hydrocarbons and their "K-region" oxides to initiate skin tumors in mice and to bind to DNA in vitro. Journal of the National Cancer Institute. 58: 1051-5. PMID 403293 DOI: 10.1093/Jnci/58.4.1051  1
1977 DiGiovanni J, Slaga TJ, Berry DL, Juchau MR. Metabolism of 7,12-dimethylbenz[a]anthracene in mouse skin homogenates analyzed with high-pressure liquid chromatography. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 5: 295-301. PMID 17529  1
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