Chambers Connor Hughes - Publications

Affiliations: 
2004 University of California, Berkeley, Berkeley, CA 

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Eichhorn JM, Alford SE, Hughes CC, Fenical W, Chambers TC. Purported Mcl-1 inhibitor marinopyrrole A fails to show selective cytotoxicity for Mcl-1-dependent cell lines. Cell Death & Disease. 4: e880. PMID 24157874 DOI: 10.1038/cddis.2013.411  1
2013 Alvarez-Mico X, Jensen PR, Fenical W, Hughes CC. Chlorizidine, a cytotoxic 5H-pyrrolo[2,1-a]isoindol-5-one-containing alkaloid from a marine Streptomyces sp. Organic Letters. 15: 988-91. PMID 23405849 DOI: 10.1021/ol303374e  1
2013 Yang M, Liu Z, Hughes C, Stern AM, Wang H, Zhong Z, Kan B, Fenical W, Zhu J. Bile salt-induced intermolecular disulfide bond formation activates Vibrio cholerae virulence. Proceedings of the National Academy of Sciences of the United States of America. 110: 2348-53. PMID 23341592 DOI: 10.1073/pnas.1218039110  1
2012 Yamanaka K, Ryan KS, Gulder TA, Hughes CC, Moore BS. Flavoenzyme-catalyzed atropo-selective N,C-bipyrrole homocoupling in marinopyrrole biosynthesis. Journal of the American Chemical Society. 134: 12434-7. PMID 22800473 DOI: 10.1021/ja305670f  1
2011 Haste NM, Hughes CC, Tran DN, Fenical W, Jensen PR, Nizet V, Hensler ME. Pharmacological properties of the marine natural product marinopyrrole A against methicillin-resistant Staphylococcus aureus. Antimicrobial Agents and Chemotherapy. 55: 3305-12. PMID 21502631 DOI: 10.1128/AAC.01211-10  1
2010 Hughes CC, Fenical W. Antibacterials from the sea. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 12512-25. PMID 20845412 DOI: 10.1002/chem.201001279  1
2010 Hughes CC, Kauffman CA, Jensen PR, Fenical W. Structures, reactivities, and antibiotic properties of the marinopyrroles A-F. The Journal of Organic Chemistry. 75: 3240-50. PMID 20405892 DOI: 10.1021/jo1002054  1
2010 Hughes CC, Fenical W. Total synthesis of the ammosamides. Journal of the American Chemical Society. 132: 2528-9. PMID 20131899 DOI: 10.1021/ja9106572  1
2010 Pangerl M, Hughes CC, Trauner D. Total synthesis of newbouldine via reductive N-N bond formation Tetrahedron. 66: 6626-6631. DOI: 10.1016/j.tet.2010.05.085  1
2009 Nett M, Gulder TA, Kale AJ, Hughes CC, Moore BS. Function-oriented biosynthesis of beta-lactone proteasome inhibitors in Salinispora tropica. Journal of Medicinal Chemistry. 52: 6163-7. PMID 19746976 DOI: 10.1021/jm901098m  1
2009 Hughes CC, Yang YL, Liu WT, Dorrestein PC, La Clair JJ, Fenical W. Marinopyrrole A target elucidation by acyl dye transfer. Journal of the American Chemical Society. 131: 12094-6. PMID 19673475 DOI: 10.1021/ja903149u  1
2009 Hughes CC, MacMillan JB, Gaudêncio SP, Fenical W, La Clair JJ. Ammosamides A and B target myosin Angewandte Chemie - International Edition. 48: 728-732. PMID 19097126 DOI: 10.1002/anie.200804107  1
2009 Hughes CC, MacMillan JB, Gaudêncio SP, Jensen PR, Fenical W. The ammosamides: Structures of cell cycle modulators from a marine-derived Streptomyces species Angewandte Chemie - International Edition. 48: 725-727. PMID 19090514 DOI: 10.1002/anie.200804890  1
2008 Hughes CC, Prieto-Davo A, Jensen PR, Fenical W. The marinopyrroles, antibiotics of an unprecedented structure class from a marine Streptomyces sp. Organic Letters. 10: 629-31. PMID 18205372 DOI: 10.1021/ol702952n  1
2006 Miller AK, Hughes CC, Kennedy-Smith JJ, Gradl SN, Trauner D. Total synthesis of (-)-heptemerone B and (-)-guanacastepene E. Journal of the American Chemical Society. 128: 17057-62. PMID 17177458 DOI: 10.1021/ja0660507  1
2005 Endicott CA, Strauss HL, Hughes CC, Trauner D. Infrared hole burning and conformational change in a borane-ammonia complex. The Journal of Physical Chemistry. A. 109: 7714-7. PMID 16834146 DOI: 10.1021/jp051969i  1
2005 Bowie AL, Hughes CC, Trauner D. Concise synthesis of (+/-)-rhazinilam through direct coupling. Organic Letters. 7: 5207-9. PMID 16268539 DOI: 10.1021/ol052033v  1
2005 Hughes CC, Miller AK, Trauner D. An electrochemical approach to the guanacastepenes. Organic Letters. 7: 3425-8. PMID 16048308 DOI: 10.1021/ol047387l  1
2004 Hughes CC, Trauner D. Palladium-catalyzed couplings to nucleophilic heteroarenes: The total synthesis of (-)-frondosin B Tetrahedron. 60: 9675-9686. DOI: 10.1016/j.tet.2004.07.041  1
2003 Hughes CC, Kennedy-Smith JJ, Trauner D. Synthetic studies toward the guanacastepenes. Organic Letters. 5: 4113-5. PMID 14572262 DOI: 10.1021/ol035559t  1
2003 Hughes CC, Trauner D. Direct Catalytic Asymmetric Amination of Aldehydes: Synthesis of Evans Oxazolidinones and α-Amino Acids Chemtracts. 16: 511-517.  1
2002 Hughes CC, Trauner D. Concise total synthesis of (-)-frondosin B using a novel palladium-catalyzed cyclization. Angewandte Chemie (International Ed. in English). 41: 1569-72. PMID 19750668 DOI: 10.1002/1521-3773(20020503)41:9<1569::AID-ANIE1569>3.0.CO;2-8  1
2002 Hughes CC, Trauner D. The total synthesis of (-)-amathaspiramide F. Angewandte Chemie (International Ed. in English). 41: 4556-9. PMID 12458537 DOI: 10.1002/1521-3773(20021202)41:23<4556::AID-ANIE4556>3.0.CO;2-E  1
2002 Hughes CC, Scharn D, Mulzer J, Trauner D. Borane-ammonia complexes stabilized by hydrogen bonding. Organic Letters. 4: 4109-11. PMID 12423098 DOI: 10.1021/ol026865u  1
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