Matthew Volgraf - Publications

Affiliations: 
2008 University of California, Berkeley, Berkeley, CA 

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Volgraf M, Sellers BD, Jiang Y, Wu G, Ly CQ, Villemure E, Pastor RM, Yuen PW, Lu A, Luo X, Liu M, Zhang S, Sun L, Fu Y, Lupardus PJ, et al. Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design. Journal of Medicinal Chemistry. PMID 26919761 DOI: 10.1021/acs.jmedchem.5b02010  0.88
2016 Hackos DH, Lupardus PJ, Grand T, Chen Y, Wang TM, Reynen P, Gustafson A, Wallweber HJ, Volgraf M, Sellers BD, Schwarz JB, Paoletti P, Sheng M, Zhou Q, Hanson JE. Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function. Neuron. PMID 26875626 DOI: 10.1016/j.neuron.2016.01.016  0.88
2014 Volgraf M, Chan L, Huestis MP, Purkey HE, Burkard M, Geck Do M, Harris J, Hunt KW, Liu X, Lyssikatos JP, Rana S, Thomas AA, Vigers GP, Siu M. Synthesis, characterization, and PK/PD studies of a series of spirocyclic pyranochromene BACE1 inhibitors. Bioorganic & Medicinal Chemistry Letters. 24: 2477-80. PMID 24780121 DOI: 10.1016/j.bmcl.2014.04.012  0.88
2014 Thomas AA, Hunt KW, Volgraf M, Watts RJ, Liu X, Vigers G, Smith D, Sammond D, Tang TP, Rhodes SP, Metcalf AT, Brown KD, Otten JN, Burkard M, Cox AA, et al. Discovery of 7-tetrahydropyran-2-yl chromans: β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors that reduce amyloid β-protein (Aβ) in the central nervous system. Journal of Medicinal Chemistry. 57: 878-902. PMID 24397738 DOI: 10.1021/jm401635n  0.88
2013 Huestis MP, Liu W, Volgraf M, Purkey HE, Yu C, Wang W, Smith D, Vigers G, Dutcher D, Hunt KW, Siu M. Diethylaminosulfur trifluoride-mediated intramolecular cyclization of 2-hydroxycycloalkylureas to fused bicyclic aminooxazoline compounds and evaluation of their biochemical activity against β-secretase-1 (BACE-1) Tetrahedron Letters. 54: 5802-5807. DOI: 10.1016/j.tetlet.2013.07.136  0.88
2012 Sofiyev V, Lumb JP, Volgraf M, Trauner D. Total synthesis of exiguamines A and B inspired by catecholamine chemistry. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 4999-5005. PMID 22415756 DOI: 10.1002/chem.201103605  0.88
2011 Volgraf M, Banghart M, Trauner D. Switchable Proteins and Channels Molecular Switches, Second Edition. 1: 563-593. DOI: 10.1002/9783527634408.ch15  0.88
2009 Numano R, Szobota S, Lau AY, Gorostiza P, Volgraf M, Roux B, Trauner D, Isacoff EY. Nanosculpting reversed wavelength sensitivity into a photoswitchable iGluR. Proceedings of the National Academy of Sciences of the United States of America. 106: 6814-9. PMID 19342491 DOI: 10.1073/pnas.0811899106  0.88
2008 Volgraf M, Lumb JP, Brastianos HC, Carr G, Chung MK, Münzel M, Mauk AG, Andersen RJ, Trauner D. Biomimetic synthesis of the IDO inhibitors exiguamine A and B. Nature Chemical Biology. 4: 535-7. PMID 18677305 DOI: 10.1038/nchembio.107  0.88
2008 Wang S, Wang Y, Szobota S, Volgraf M, Liu Z, Sun C, Trauner D, Isacoff EY, Zhang X. All optical platform for parallel and spatiotemporal control of neuronal activity Optics Infobase Conference Papers 0.88
2007 Wang S, Szobota S, Wang Y, Volgraf M, Liu Z, Sun C, Trauner D, Isacoff EY, Zhang X. All optical interface for parallel, remote, and spatiotemporal control of neuronal activity. Nano Letters. 7: 3859-63. PMID 18034506 DOI: 10.1021/nl072783t  0.88
2007 Gorostiza P, Volgraf M, Numano R, Szobota S, Trauner D, Isacoff EY. Mechanisms of photoswitch conjugation and light activation of an ionotropic glutamate receptor. Proceedings of the National Academy of Sciences of the United States of America. 104: 10865-70. PMID 17578923 DOI: 10.1073/pnas.0701274104  0.88
2007 Szobota S, Gorostiza P, Del Bene F, Wyart C, Fortin DL, Kolstad KD, Tulyathan O, Volgraf M, Numano R, Aaron HL, Scott EK, Kramer RH, Flannery J, Baier H, Trauner D, et al. Remote control of neuronal activity with a light-gated glutamate receptor. Neuron. 54: 535-45. PMID 17521567 DOI: 10.1016/j.neuron.2007.05.010  0.88
2007 Volgraf M, Gorostiza P, Szobota S, Helix MR, Isacoff EY, Trauner D. Reversibly caged glutamate: a photochromic agonist of ionotropic glutamate receptors. Journal of the American Chemical Society. 129: 260-1. PMID 17212390 DOI: 10.1021/ja067269o  0.88
2006 Banghart MR, Volgraf M, Trauner D. Engineering light-gated ion channels. Biochemistry. 45: 15129-41. PMID 17176035 DOI: 10.1021/bi0618058  0.88
2006 Volgraf M, Gorostiza P, Numano R, Kramer RH, Isacoff EY, Trauner D. Allosteric control of an ionotropic glutamate receptor with an optical switch. Nature Chemical Biology. 2: 47-52. PMID 16408092 DOI: 10.1038/nchembio756  0.88
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