Bradley S. Moore - Publications

Affiliations: 
1996-1999 University of Washington, Seattle, Seattle, WA 
 1999-2005 University of Arizona, Tucson, AZ 
 2005- Pharmacy University of California, San Diego, La Jolla, CA 
Website:
http://pharmacy.ucsd.edu/faculty/bios/moore.shtml

187 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Tang X, Kudo Y, Baker J, LaBonte S, Jordan P, McKinnie S, Guo J, Huan T, Moore BS, Edlund A. Cariogenic produces tetramic acid strain-specific antibiotics that impair commensal colonization. Acs Infectious Diseases. PMID 31906623 DOI: 10.1021/acsinfecdis.9b00365  0.72
2019 Zhang JJ, Tang X, Huan T, Ross AC, Moore BS. Pass-back chain extension expands multimodular assembly line biosynthesis. Nature Chemical Biology. PMID 31636431 DOI: 10.1038/s41589-019-0385-4  0.76
2019 Li ZR, Li J, Cai W, Lai JYH, McKinnie SMK, Zhang WP, Moore BS, Zhang W, Qian PY. Macrocyclic colibactin induces DNA double-strand breaks via copper-mediated oxidative cleavage. Nature Chemistry. PMID 31527851 DOI: 10.1038/s41557-019-0317-7  0.72
2019 Zhang JJ, Tang X, Moore BS. Genetic platforms for heterologous expression of microbial natural products. Natural Product Reports. PMID 31197291 DOI: 10.1039/c9np00025a  0.72
2019 Zhang JJ, Yamanaka K, Tang X, Moore BS. Direct cloning and heterologous expression of natural product biosynthetic gene clusters by transformation-associated recombination. Methods in Enzymology. 621: 87-110. PMID 31128791 DOI: 10.1016/bs.mie.2019.02.026  0.72
2019 Chekan JR, Lee GY, El Gamal A, Purdy TN, Houk KN, Moore BS. Bacterial Tetrabromopyrrole Debrominase Shares a Reductive Dehalogenation Strategy with Human Thyroid Deiodinase. Biochemistry. PMID 31117392 DOI: 10.1021/acs.biochem.9b00318  0.4
2019 Chekan JR, McKinnie SMK, Moore ML, Poplawski SG, Michael TP, Moore BS. Scalable biosynthesis of the seaweed neurochemical kainic acid. Angewandte Chemie (International Ed. in English). PMID 30995339 DOI: 10.1002/anie.201902910  0.72
2019 Moore BS, Luhavaya H, Sigrist R, Chekan JR, McKinnie SMK. Biosynthesis of L-4-Chlorokynurenine, a Lipopeptide Antibiotic Non-Proteinogenic Amino Acid and Antidepressant Prodrug. Angewandte Chemie (International Ed. in English). PMID 30963655 DOI: 10.1002/anie.201901571  0.72
2019 Rothe ML, Li J, Garibay E, Moore BS, McKinnie SMK. Synthesis, bioactivity, and enzymatic modification of antibacterial thiotetromycin derivatives. Organic & Biomolecular Chemistry. PMID 30869693 DOI: 10.1039/c8ob03109f  0.72
2019 Bauman KD, Li J, Murata K, Mantovani SM, Dahesh S, Nizet V, Luhavaya H, Moore BS. Refactoring the Cryptic Streptophenazine Biosynthetic Gene Cluster Unites Phenazine, Polyketide, and Nonribosomal Peptide Biochemistry. Cell Chemical Biology. PMID 30853419 DOI: 10.1016/j.chembiol.2019.02.004  0.72
2019 Busch J, Agarwal V, Schorn M, Machado H, Moore BS, Rouse GW, Gram L, Jensen PR. Diversity and Distribution of the bmp Gene Cluster and its Products in the Genus Pseudoalteromonas. Environmental Microbiology. PMID 30652406 DOI: 10.1111/1462-2920.14532  0.36
2018 McKinnie S, Miles ZD, Jordan PA, Awakawa T, Pepper HP, Murray LAM, George JH, Moore BS. Total enzyme syntheses of napyradiomycins A1 and B1. Journal of the American Chemical Society. PMID 30525563 DOI: 10.1021/jacs.8b10134  0.6
2018 McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, ... ... Moore BS, et al. Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Natural Product Reports. PMID 30468235 DOI: 10.1039/c8np90041h  0.72
2018 Brunson JK, McKinnie SMK, Chekan JR, McCrow JP, Miles ZD, Bertrand EM, Bielinski VA, Luhavaya H, Oborník M, Smith GJ, Hutchins DA, Allen AE, Moore BS. Biosynthesis of the neurotoxin domoic acid in a bloom-forming diatom. Science (New York, N.Y.). 361: 1356-1358. PMID 30262498 DOI: 10.1126/science.aau0382  0.72
2018 Zhang JJ, Moore BS, Tang X. Engineering Salinispora tropica for heterologous expression of natural product biosynthetic gene clusters. Applied Microbiology and Biotechnology. PMID 30105571 DOI: 10.1007/s00253-018-9283-z  0.72
2018 McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, ... ... Moore BS, et al. The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Natural Product Reports. PMID 30003207 DOI: 10.1039/c7np00064b  0.72
2018 Zheng J, McKinnie SMK, El Gamal A, Feng W, Dong Y, Agarwal V, Fenical W, Kumar A, Cao Z, Moore BS, Pessah IN. Correction to Organohalogens Naturally Biosynthesized in Marine Environments and Produced As Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum Ca Dynamics. Environmental Science & Technology. PMID 29916692 DOI: 10.1021/acs.est.8b03174  0.72
2018 Chekan JR, Moore BS. Preparation and Characterization of Tetrabromopyrrole Debrominase From Marine Proteobacteria. Methods in Enzymology. 605: 253-265. PMID 29909826 DOI: 10.1016/bs.mie.2018.01.031  0.4
2018 McKinnie SMK, Miles ZD, Moore BS. Characterization and Biochemical Assays of Streptomyces Vanadium-Dependent Chloroperoxidases. Methods in Enzymology. 604: 405-424. PMID 29779661 DOI: 10.1016/bs.mie.2018.02.016  0.72
2018 Zheng J, Mckinnie SMK, Gamal AE, Feng W, Dong Y, Agarwal V, Fenical W, Kumar A, Cao Z, Moore BS, Pessah IN. Organohalogens naturally biosynthesized in marine environments and produced as disinfection by-products alter sarco/endoplasmic reticulum Cadynamics. Environmental Science & Technology. PMID 29617551 DOI: 10.1021/acs.est.8b00512  0.72
2018 Chekan JR, Moore BS. Biosynthesis of the Antibiotic Bicyclomycin in Soil and Pathogenic Bacteria. Biochemistry. PMID 29313351 DOI: 10.1021/acs.biochem.7b01204  0.4
2017 Reynolds KA, Luhavaya H, Li J, Dahesh S, Nizet V, Yamanaka K, Moore BS. Isolation and structure elucidation of lipopeptide antibiotic taromycin B from the activated taromycin biosynthetic gene cluster. The Journal of Antibiotics. PMID 29184121 DOI: 10.1038/ja.2017.146  0.72
2017 Miles ZD, Diethelm S, Pepper HP, Huang DM, George JH, Moore BS. A unifying paradigm for naphthoquinone-based meroterpenoid (bio)synthesis. Nature Chemistry. 9: 1235-1242. PMID 29168495 DOI: 10.1038/nchem.2829  0.32
2017 Zhang JJ, Tang X, Zhang M, Nguyen D, Moore BS. Broad-Host-Range Expression Reveals Native and Host Regulatory Elements That Influence Heterologous Antibiotic Production in Gram-Negative Bacteria. Mbio. 8. PMID 28874475 DOI: 10.1128/mBio.01291-17  0.72
2017 Li J, Tang X, Awakawa T, Moore BS. Enzymatic C-H Amidation in the Production of Natural and Unnatural Thiotetronate Antibiotics with Potentiated Bioactivity. Angewandte Chemie (International Ed. in English). PMID 28833969 DOI: 10.1002/anie.201705239  0.72
2017 Bruns H, Crüsemann M, Letzel AC, Alanjary M, McInerney JO, Jensen PR, Schulz S, Moore BS, Ziemert N. Function-related replacement of bacterial siderophore pathways. The Isme Journal. PMID 28809850 DOI: 10.1038/ismej.2017.137  0.36
2017 Letzel AC, Jing L, Amos G, Millán-Aguiñaga N, Ginigini J, Abdelmohsen UR, Gaudêncio SP, Ziemert N, Moore BS, Jensen PR. Genomic Insights into Specialized Metabolism in the Marine Actinomycete Salinispora. Environmental Microbiology. PMID 28752948 DOI: 10.1111/1462-2920.13867  0.36
2017 Tang X, Li J, Moore BS. Minimization of the Thiolactomycin Biosynthetic Pathway Reveals that the Cytochrome P450 Enzyme TlmF is Required for Five-membered Thiolactone Ring Formation. Chembiochem : a European Journal of Chemical Biology. PMID 28393452 DOI: 10.1002/cbic.201700090  0.72
2017 Crüsemann M, O'Neill EC, Larson CB, Melnik AV, Floros DJ, da Silva RR, Jensen PR, Dorrestein PC, Moore BS. Prioritizing Natural Product Diversity in a Collection of 146 Bacterial Strains Based on Growth and Extraction Protocols. Journal of Natural Products. 80: 588-597. PMID 28335604 DOI: 10.1021/acs.jnatprod.6b00722  0.76
2017 Agarwal V, Blanton JM, Podell S, Taton A, Schorn MA, Busch J, Lin Z, Schmidt EW, Jensen PR, Paul VJ, Biggs JS, Golden JW, Allen EE, Moore BS. Metagenomic discovery of polybrominated diphenyl ether biosynthesis by marine sponges. Nature Chemical Biology. PMID 28319100 DOI: 10.1038/nchembio.2330  0.36
2017 Nguyen DD, Melnik AV, Koyama N, Lu X, Schorn M, Fang J, Aguinaldo K, Lincecum TL, Ghequire MG, Carrion VJ, Cheng TL, Duggan BM, Malone JG, Mauchline TH, Sanchez LM, ... ... Moore BS, et al. Erratum: Indexing the Pseudomonas specialized metabolome enabled the discovery of poaeamide B and the bananamides. Nature Microbiology. 2: 17010. PMID 28112718 DOI: 10.1038/nmicrobiol.2017.10  0.76
2017 Agarwal V, Miles ZD, Winter JM, Eustáquio AS, El Gamal AA, Moore BS. Enzymatic Halogenation and Dehalogenation Reactions: Pervasive and Mechanistically Diverse. Chemical Reviews. PMID 28106994 DOI: 10.1021/acs.chemrev.6b00571  0.8
2016 Patin NV, Schorn M, Aguinaldo K, Lincecum T, Moore BS, Jensen PR. Effects of actinomycete secondary metabolites on sediment microbial communities. Applied and Environmental Microbiology. PMID 27986719 DOI: 10.1128/AEM.02676-16  0.36
2016 Schorn MA, Alanjary MM, Aguinaldo K, Korobeynikov A, Podell S, Patin NV, Lincecum T, Jensen PR, Ziemert N, Moore BS. Sequencing Rare Marine Actinomycete Genomes Reveals High Density of Unique Natural Product Biosynthetic Gene Clusters. Microbiology (Reading, England). PMID 27902408 DOI: 10.1099/mic.0.000386  0.36
2016 Zhang W, Lu L, Lai Q, Zhu B, Li Z, Xu Y, Shao Z, Herrup K, Moore BS, Ross AC, Qian PY. Family-wide structural characterization and genomic comparisons decode diversity-oriented biosynthesis of thalassospiramides by marine proteobacteria. The Journal of Biological Chemistry. PMID 27875306 DOI: 10.1074/jbc.M116.756858  0.76
2016 Nguyen DD, Melnik AV, Koyama N, Lu X, Schorn M, Fang J, Aguinaldo K, Lincecum TL, Ghequire MG, Carrion VJ, Cheng TL, Duggan BM, Malone JG, Mauchline TH, Sanchez LM, ... ... Moore BS, et al. Indexing the Pseudomonas specialized metabolome enabled the discovery of poaeamide B and the bananamides. Nature Microbiology. 2: 16197. PMID 27798598 DOI: 10.1038/nmicrobiol.2016.197  0.76
2016 Li ZR, Li J, Gu JP, Lai JY, Duggan BM, Zhang WP, Li ZL, Li YX, Tong RB, Xu Y, Lin DH, Moore BS, Qian PY. Divergent biosynthesis yields a cytotoxic aminomalonate-containing precolibactin. Nature Chemical Biology. PMID 27547923 DOI: 10.1038/nchembio.2157  1
2016 Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, ... ... Moore BS, et al. Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. Nature Biotechnology. 34: 828-837. PMID 27504778 DOI: 10.1038/nbt.3597  1
2016 El Gamal A, Agarwal V, Diethelm S, Rahman I, Schorn MA, Sneed JM, Louie GV, Whalen KE, Mincer TJ, Noel JP, Paul VJ, Moore BS. Biosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase-thioesterase enzyme pair. Proceedings of the National Academy of Sciences of the United States of America. PMID 27001835 DOI: 10.1073/pnas.1519695113  1
2016 Harvey EL, Deering RW, Rowley DC, El Gamal A, Schorn M, Moore BS, Johnson MD, Mincer TJ, Whalen KE. A Bacterial Quorum-Sensing Precursor Induces Mortality in the Marine Coccolithophore, Emiliania huxleyi. Frontiers in Microbiology. 7: 59. PMID 26870019 DOI: 10.3389/fmicb.2016.00059  1
2016 Teufel R, Agarwal V, Moore BS. Unusual flavoenzyme catalysis in marine bacteria. Current Opinion in Chemical Biology. 31: 31-39. PMID 26803009 DOI: 10.1016/j.cbpa.2016.01.001  1
2015 Ray L, Moore BS. Recent advances in the biosynthesis of unusual polyketide synthase substrates. Natural Product Reports. PMID 26571143 DOI: 10.1039/c5np00112a  1
2015 Ray L, Yamanaka K, Moore BS. A Peptidyl-Transesterifying Type I Thioesterase in Salinamide Biosynthesis. Angewandte Chemie (International Ed. in English). PMID 26553755 DOI: 10.1002/anie.201508576  1
2015 Kim E, Moore BS, Yoon YJ. Erratum: Reinvigorating natural product combinatorial biosynthesis with synthetic biology. Nature Chemical Biology. 11: 887. PMID 26485082 DOI: 10.1038/nchembio1115-887a  0.36
2015 Tang X, Li J, Millán-Aguiñaga N, Zhang JJ, O'Neill EC, Ugalde JA, Jensen PR, Mantovani SM, Moore BS. Identification of Thiotetronic Acid Antibiotic Biosynthetic Pathways by Target-directed Genome Mining. Acs Chemical Biology. PMID 26458099 DOI: 10.1021/acschembio.5b00658  1
2015 Agarwal V, Diethelm S, Ray L, Garg N, Awakawa T, Dorrestein PC, Moore BS. Chemoenzymatic Synthesis of Acyl Coenzyme A Substrates Enables in Situ Labeling of Small Molecules and Proteins. Organic Letters. 17: 4452-5. PMID 26333306 DOI: 10.1021/acs.orglett.5b02113  1
2015 Kim E, Moore BS, Yoon YJ. Reinvigorating natural product combinatorial biosynthesis with synthetic biology. Nature Chemical Biology. 11: 649-59. PMID 26284672 DOI: 10.1038/nchembio.1893  0.36
2015 Teufel R, Stull F, Meehan MJ, Michaudel Q, Dorrestein PC, Palfey B, Moore BS. Biochemical Establishment and Characterization of EncM's Flavin-N5-oxide Cofactor. Journal of the American Chemical Society. 137: 8078-85. PMID 26067765 DOI: 10.1021/jacs.5b03983  1
2015 Awakawa T, Crüsemann M, Munguia J, Ziemert N, Nizet V, Fenical W, Moore BS. Salinipyrone and Pacificanone Are Biosynthetic By-products of the Rosamicin Polyketide Synthase. Chembiochem : a European Journal of Chemical Biology. 16: 1443-7. PMID 25930739 DOI: 10.1002/cbic.201500177  1
2015 Duncan KR, Crüsemann M, Lechner A, Sarkar A, Li J, Ziemert N, Wang M, Bandeira N, Moore BS, Dorrestein PC, Jensen PR. Molecular networking and pattern-based genome mining improves discovery of biosynthetic gene clusters and their products from Salinispora species. Chemistry & Biology. 22: 460-71. PMID 25865308 DOI: 10.1016/j.chembiol.2015.03.010  1
2015 Li Y, Li Z, Yamanaka K, Xu Y, Zhang W, Vlamakis H, Kolter R, Moore BS, Qian PY. Directed natural product biosynthesis gene cluster capture and expression in the model bacterium Bacillus subtilis. Scientific Reports. 5: 9383. PMID 25807046 DOI: 10.1038/srep09383  1
2015 Lu L, Meehan MJ, Gu S, Chen Z, Zhang W, Zhang G, Liu L, Huang X, Dorrestein PC, Xu Y, Moore BS, Qian PY. Mechanism of action of thalassospiramides, a new class of calpain inhibitors. Scientific Reports. 5: 8783. PMID 25740631 DOI: 10.1038/srep08783  1
2015 Jensen PR, Moore BS, Fenical W. The marine actinomycete genus Salinispora: a model organism for secondary metabolite discovery. Natural Product Reports. 32: 738-51. PMID 25730728 DOI: 10.1039/c4np00167b  1
2015 Zhang JJ, Moore BS. Digging for biosynthetic dark matter. Elife. 4: e06453. PMID 25687291 DOI: 10.7554/eLife.06453  1
2015 Charlop-Powers Z, Owen JG, Reddy BV, Ternei MA, Guimarães DO, de Frias UA, Pupo MT, Seepe P, Feng Z, Brady SF. Global biogeographic sampling of bacterial secondary metabolism. Elife. 4: e05048. PMID 25599565 DOI: 10.7554/eLife.05048  1
2015 Agarwal V, Li J, Rahman I, Borgen M, Aluwihare LI, Biggs JS, Paul VJ, Moore BS. Complexity of naturally produced polybrominated diphenyl ethers revealed via mass spectrometry. Environmental Science & Technology. 49: 1339-46. PMID 25559102 DOI: 10.1021/es505440j  1
2015 Bonet B, Teufel R, Crüsemann M, Ziemert N, Moore BS. Direct capture and heterologous expression of Salinispora natural product genes for the biosynthesis of enterocin. Journal of Natural Products. 78: 539-42. PMID 25382643 DOI: 10.1021/np500664q  1
2015 Richter TK, Hughes CC, Moore BS. Sioxanthin, a novel glycosylated carotenoid, reveals an unusual subclustered biosynthetic pathway. Environmental Microbiology. 17: 2158-71. PMID 25329237 DOI: 10.1111/1462-2920.12669  1
2015 Ross AC, Gulland LE, Dorrestein PC, Moore BS. Targeted capture and heterologous expression of the Pseudoalteromonas alterochromide gene cluster in Escherichia coli represents a promising natural product exploratory platform. Acs Synthetic Biology. 4: 414-20. PMID 25140825 DOI: 10.1021/sb500280q  1
2015 Kim E, Moore BS, Yoon YJ. Reinvigorating natural product combinatorial biosynthesis with synthetic biology Nature Chemical Biology. 11: 649-659. DOI: 10.1038/nchembio.1893  1
2014 Xu M, Hillwig ML, Lane AL, Tiernan MS, Moore BS, Peters RJ. Characterization of an orphan diterpenoid biosynthetic operon from Salinispora arenicola. Journal of Natural Products. 77: 2144-7. PMID 25203741 DOI: 10.1021/np500422d  1
2014 Diethelm S, Teufel R, Kaysser L, Moore BS. A multitasking vanadium-dependent chloroperoxidase as an inspiration for the chemical synthesis of the merochlorins. Angewandte Chemie (International Ed. in English). 53: 11023-6. PMID 25147132 DOI: 10.1002/anie.201405696  1
2014 Agarwal V, Moore BS. Fungal polyketide engineering comes of age. Proceedings of the National Academy of Sciences of the United States of America. 111: 12278-9. PMID 25118274 DOI: 10.1073/pnas.1412946111  1
2014 Mohimani H, Liu WT, Kersten RD, Moore BS, Dorrestein PC, Pevzner PA. NRPquest: Coupling Mass Spectrometry and Genome Mining for Nonribosomal Peptide Discovery. Journal of Natural Products. PMID 25116163 DOI: 10.1021/np500370c  1
2014 Teufel R, Kaysser L, Villaume MT, Diethelm S, Carbullido MK, Baran PS, Moore BS. One-pot enzymatic synthesis of merochlorin A and B. Angewandte Chemie (International Ed. in English). 53: 11019-22. PMID 25115835 DOI: 10.1002/anie.201405694  1
2014 Agarwal V, Moore BS. Enzymatic synthesis of polybrominated dioxins from the marine environment. Acs Chemical Biology. 9: 1980-4. PMID 25061970 DOI: 10.1021/cb5004338  1
2014 Agarwal V, El Gamal AA, Yamanaka K, Poth D, Kersten RD, Schorn M, Allen EE, Moore BS. Biosynthesis of polybrominated aromatic organic compounds by marine bacteria. Nature Chemical Biology. 10: 640-7. PMID 24974229 DOI: 10.1038/nchembio.1564  1
2014 Trivella DB, Pereira AR, Stein ML, Kasai Y, Byrum T, Valeriote FA, Tantillo DJ, Groll M, Gerwick WH, Moore BS. Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor. Chemistry & Biology. 21: 782-91. PMID 24930969 DOI: 10.1016/j.chembiol.2014.04.010  1
2014 Mohimani H, Kersten RD, Liu WT, Wang M, Purvine SO, Wu S, Brewer HM, Pasa-Tolic L, Bandeira N, Moore BS, Pevzner PA, Dorrestein PC. Automated genome mining of ribosomal peptide natural products. Acs Chemical Biology. 9: 1545-51. PMID 24802639 DOI: 10.1021/cb500199h  1
2014 Niewerth D, Jansen G, Riethoff LF, van Meerloo J, Kale AJ, Moore BS, Assaraf YG, Anderl JL, Zweegman S, Kaspers GJ, Cloos J. Antileukemic activity and mechanism of drug resistance to the marine Salinispora tropica proteasome inhibitor salinosporamide A (Marizomib). Molecular Pharmacology. 86: 12-9. PMID 24737138 DOI: 10.1124/mol.114.092114  1
2014 Yamanaka K, Reynolds KA, Kersten RD, Ryan KS, Gonzalez DJ, Nizet V, Dorrestein PC, Moore BS. Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A. Proceedings of the National Academy of Sciences of the United States of America. 111: 1957-62. PMID 24449899 DOI: 10.1073/pnas.1319584111  1
2014 Jordan PA, Moore BS. Biosynthesis: Non-stick natural products. Nature Chemistry. 6: 10-2. PMID 24345935 DOI: 10.1038/nchem.1828  1
2014 Schorn M, Zettler J, Noel JP, Dorrestein PC, Moore BS, Kaysser L. Genetic basis for the biosynthesis of the pharmaceutically important class of epoxyketone proteasome inhibitors. Acs Chemical Biology. 9: 301-9. PMID 24168704 DOI: 10.1021/cb400699p  1
2014 Liu WT, Lamsa A, Wong WR, Boudreau PD, Kersten R, Peng Y, Moree WJ, Duggan BM, Moore BS, Gerwick WH, Linington RG, Pogliano K, Dorrestein PC. MS/MS-based networking and peptidogenomics guided genome mining revealed the stenothricin gene cluster in Streptomyces roseosporus. The Journal of Antibiotics. 67: 99-104. PMID 24149839 DOI: 10.1038/ja.2013.99  1
2014 Jensen PR, Chavarria KL, Fenical W, Moore BS, Ziemert N. Challenges and triumphs to genomics-based natural product discovery. Journal of Industrial Microbiology & Biotechnology. 41: 203-9. PMID 24104399 DOI: 10.1007/s10295-013-1353-8  1
2013 Mantovani SM, Moore BS. Flavin-linked oxidase catalyzes pyrrolizine formation of dichloropyrrole-containing polyketide extender unit in chlorizidine A. Journal of the American Chemical Society. 135: 18032-5. PMID 24246014 DOI: 10.1021/ja409520v  1
2013 Kersten RD, Ziemert N, Gonzalez DJ, Duggan BM, Nizet V, Dorrestein PC, Moore BS. Glycogenomics as a mass spectrometry-guided genome-mining method for microbial glycosylated molecules. Proceedings of the National Academy of Sciences of the United States of America. 110: E4407-16. PMID 24191063 DOI: 10.1073/pnas.1315492110  1
2013 Teufel R, Miyanaga A, Michaudel Q, Stull F, Louie G, Noel JP, Baran PS, Palfey B, Moore BS. Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement. Nature. 503: 552-6. PMID 24162851 DOI: 10.1038/nature12643  1
2013 Horsman GP, Lechner A, Ohnishi Y, Moore BS, Shen B. Predictive model for epoxide hydrolase-generated stereochemistry in the biosynthesis of nine-membered enediyne antitumor antibiotics. Biochemistry. 52: 5217-24. PMID 23844627 DOI: 10.1021/bi400572a  1
2013 Nguyen DD, Wu CH, Moree WJ, Lamsa A, Medema MH, Zhao X, Gavilan RG, Aparicio M, Atencio L, Jackson C, Ballesteros J, Sanchez J, Watrous JD, Phelan VV, van de Wiel C, ... ... Moore BS, et al. MS/MS networking guided analysis of molecule and gene cluster families. Proceedings of the National Academy of Sciences of the United States of America. 110: E2611-20. PMID 23798442 DOI: 10.1073/pnas.1303471110  1
2013 Lechner A, Wilson MC, Ban YH, Hwang JY, Yoon YJ, Moore BS. Designed biosynthesis of 36-methyl-FK506 by polyketide precursor pathway engineering. Acs Synthetic Biology. 2: 379-83. PMID 23654255 DOI: 10.1021/sb3001062  1
2013 Lipson JM, Thomsen M, Moore BS, Clausen RP, La Clair JJ, Burkart MD. A tandem chemoenzymatic methylation by S-adenosyl-L-methionine. Chembiochem : a European Journal of Chemical Biology. 14: 950-3. PMID 23650044 DOI: 10.1002/cbic.201300221  1
2013 Kersten RD, Lane AL, Nett M, Richter TK, Duggan BM, Dorrestein PC, Moore BS. Bioactivity-guided genome mining reveals the lomaiviticin biosynthetic gene cluster in Salinispora tropica. Chembiochem : a European Journal of Chemical Biology. 14: 955-62. PMID 23649992 DOI: 10.1002/cbic.201300147  1
2013 Lane AL, Nam SJ, Fukuda T, Yamanaka K, Kauffman CA, Jensen PR, Fenical W, Moore BS. Structures and comparative characterization of biosynthetic gene clusters for cyanosporasides, enediyne-derived natural products from marine actinomycetes. Journal of the American Chemical Society. 135: 4171-4. PMID 23458364 DOI: 10.1021/ja311065v  1
2013 Ross AC, Xu Y, Lu L, Kersten RD, Shao Z, Al-Suwailem AM, Dorrestein PC, Qian PY, Moore BS. Biosynthetic multitasking facilitates thalassospiramide structural diversity in marine bacteria. Journal of the American Chemical Society. 135: 1155-62. PMID 23270364 DOI: 10.1021/ja3119674  1
2013 Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, ... ... Moore BS, et al. Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Natural Product Reports. 30: 108-60. PMID 23165928 DOI: 10.1039/c2np20085f  1
2012 Kale AJ, Moore BS. Molecular mechanisms of acquired proteasome inhibitor resistance. Journal of Medicinal Chemistry. 55: 10317-27. PMID 22978849 DOI: 10.1021/jm300434z  1
2012 Richter M, Busch B, Ishida K, Moore BS, Hertweck C. Pyran formation by an atypical CYP-mediated four-electron oxygenation-cyclization cascade in an engineered aureothin pathway. Chembiochem : a European Journal of Chemical Biology. 13: 2196-9. PMID 22961965 DOI: 10.1002/cbic.201200406  1
2012 Qian Q, Schultz AW, Moore BS, Tanner ME. Mechanistic studies on CymD: a tryptophan reverse N-prenyltransferase. Biochemistry. 51: 7733-9. PMID 22935004 DOI: 10.1021/bi3009054  1
2012 Tsai SC, Moore B, O'Connor S. Editorial: structural aspects of biosynthesis themed issue. Natural Product Reports. 29: 1032. PMID 22930328 DOI: 10.1039/c2np90032g  1
2012 Yang JY, Phelan VV, Simkovsky R, Watrous JD, Trial RM, Fleming TC, Wenter R, Moore BS, Golden SS, Pogliano K, Dorrestein PC. Primer on agar-based microbial imaging mass spectrometry. Journal of Bacteriology. 194: 6023-8. PMID 22821974 DOI: 10.1128/JB.00823-12  1
2012 Roberts AA, Schultz AW, Kersten RD, Dorrestein PC, Moore BS. Iron acquisition in the marine actinomycete genus Salinispora is controlled by the desferrioxamine family of siderophores. Fems Microbiology Letters. 335: 95-103. PMID 22812504 DOI: 10.1111/j.1574-6968.2012.02641.x  1
2012 Yamanaka K, Ryan KS, Gulder TA, Hughes CC, Moore BS. Flavoenzyme-catalyzed atropo-selective N,C-bipyrrole homocoupling in marinopyrrole biosynthesis. Journal of the American Chemical Society. 134: 12434-7. PMID 22800473 DOI: 10.1021/ja305670f  1
2012 Kaysser L, Bernhardt P, Nam SJ, Loesgen S, Ruby JG, Skewes-Cox P, Jensen PR, Fenical W, Moore BS. Merochlorins A-D, cyclic meroterpenoid antibiotics biosynthesized in divergent pathways with vanadium-dependent chloroperoxidases. Journal of the American Chemical Society. 134: 11988-91. PMID 22784372 DOI: 10.1021/ja305665f  1
2012 Watrous J, Roach P, Alexandrov T, Heath BS, Yang JY, Kersten RD, van der Voort M, Pogliano K, Gross H, Raaijmakers JM, Moore BS, Laskin J, Bandeira N, Dorrestein PC. Mass spectral molecular networking of living microbial colonies. Proceedings of the National Academy of Sciences of the United States of America. 109: E1743-52. PMID 22586093 DOI: 10.1073/pnas.1203689109  1
2012 Xu Y, Kersten RD, Nam SJ, Lu L, Al-Suwailem AM, Zheng H, Fenical W, Dorrestein PC, Moore BS, Qian PY. Bacterial biosynthesis and maturation of the didemnin anti-cancer agents. Journal of the American Chemical Society. 134: 8625-32. PMID 22458477 DOI: 10.1021/ja301735a  1
2012 Pereira AR, Kale AJ, Fenley AT, Byrum T, Debonsi HM, Gilson MK, Valeriote FA, Moore BS, Gerwick WH. The carmaphycins: new proteasome inhibitors exhibiting an α,β-epoxyketone warhead from a marine cyanobacterium. Chembiochem : a European Journal of Chemical Biology. 13: 810-7. PMID 22383253 DOI: 10.1002/cbic.201200007  1
2012 Gonzalez DJ, Okumura CY, Hollands A, Kersten R, Akong-Moore K, Pence MA, Malone CL, Derieux J, Moore BS, Horswill AR, Dixon JE, Dorrestein PC, Nizet V. Novel phenol-soluble modulin derivatives in community-associated methicillin-resistant Staphylococcus aureus identified through imaging mass spectrometry. The Journal of Biological Chemistry. 287: 13889-98. PMID 22371493 DOI: 10.1074/jbc.M112.349860  1
2012 Jones AC, Ottilie S, Eustáquio AS, Edwards DJ, Gerwick L, Moore BS, Gerwick WH. Evaluation of Streptomyces coelicolor A3(2) as a heterologous expression host for the cyanobacterial protein kinase C activator lyngbyatoxin A. The Febs Journal. 279: 1243-51. PMID 22314229 DOI: 10.1111/j.1742-4658.2012.08517.x  1
2012 Gerwick WH, Moore BS. Lessons from the past and charting the future of marine natural products drug discovery and chemical biology. Chemistry & Biology. 19: 85-98. PMID 22284357 DOI: 10.1016/j.chembiol.2011.12.014  1
2012 Wilson MC, Moore BS. Beyond ethylmalonyl-CoA: the functional role of crotonyl-CoA carboxylase/reductase homologs in expanding polyketide diversity. Natural Product Reports. 29: 72-86. PMID 22124767 DOI: 10.1039/c1np00082a  1
2012 Chen ZH, Wang BL, Kale AJ, Moore BS, Wang RW, Qing FL. Coupling of sterically hindered aldehyde with fluorinated synthons: Stereoselective synthesis of fluorinated analogues of salinosporamide A Journal of Fluorine Chemistry. 136: 12-19. DOI: 10.1016/j.jfluchem.2012.01.003  1
2011 Lechner A, Eustáquio AS, Gulder TA, Hafner M, Moore BS. Selective overproduction of the proteasome inhibitor salinosporamide A via precursor pathway regulation. Chemistry & Biology. 18: 1527-36. PMID 22195555 DOI: 10.1016/j.chembiol.2011.10.014  1
2011 Liu WT, Kersten RD, Yang YL, Moore BS, Dorrestein PC. Imaging mass spectrometry and genome mining via short sequence tagging identified the anti-infective agent arylomycin in Streptomyces roseosporus. Journal of the American Chemical Society. 133: 18010-3. PMID 21999343 DOI: 10.1021/ja2040877  1
2011 Kersten RD, Yang YL, Xu Y, Cimermancic P, Nam SJ, Fenical W, Fischbach MA, Moore BS, Dorrestein PC. A mass spectrometry-guided genome mining approach for natural product peptidogenomics. Nature Chemical Biology. 7: 794-802. PMID 21983601 DOI: 10.1038/nchembio.684  1
2011 Kale AJ, McGlinchey RP, Lechner A, Moore BS. Bacterial self-resistance to the natural proteasome inhibitor salinosporamide A. Acs Chemical Biology. 6: 1257-64. PMID 21882868 DOI: 10.1021/cb2002544  1
2011 Miyanaga A, Janso JE, McDonald L, He M, Liu H, Barbieri L, Eustáquio AS, Fielding EN, Carter GT, Jensen PR, Feng X, Leighton M, Koehn FE, Moore BS. Discovery and assembly-line biosynthesis of the lymphostin pyrroloquinoline alkaloid family of mTOR inhibitors in Salinispora bacteria. Journal of the American Chemical Society. 133: 13311-3. PMID 21815669 DOI: 10.1021/ja205655w  1
2011 Yang YL, Xu Y, Kersten RD, Liu WT, Meehan MJ, Moore BS, Bandeira N, Dorrestein PC. Connecting chemotypes and phenotypes of cultured marine microbial assemblages by imaging mass spectrometry. Angewandte Chemie (International Ed. in English). 50: 5839-42. PMID 21574228 DOI: 10.1002/anie.201101225  1
2011 Kalaitzis JA, Cheng Q, Meluzzi D, Xiang L, Izumikawa M, Dorrestein PC, Moore BS. Policing starter unit selection of the enterocin type II polyketide synthase by the type II thioesterase EncL. Bioorganic & Medicinal Chemistry. 19: 6633-8. PMID 21531566 DOI: 10.1016/j.bmc.2011.04.024  1
2011 Udwary DW, Gontang EA, Jones AC, Jones CS, Schultz AW, Winter JM, Yang JY, Beauchemin N, Capson TL, Clark BR, Esquenazi E, Eustáquio AS, Freel K, Gerwick L, Gerwick WH, ... ... Moore BS, et al. Significant natural product biosynthetic potential of actinorhizal symbionts of the genus frankia, as revealed by comparative genomic and proteomic analyses. Applied and Environmental Microbiology. 77: 3617-25. PMID 21498757 DOI: 10.1128/AEM.00038-11  1
2011 Bernhardt P, Okino T, Winter JM, Miyanaga A, Moore BS. A stereoselective vanadium-dependent chloroperoxidase in bacterial antibiotic biosynthesis. Journal of the American Chemical Society. 133: 4268-70. PMID 21384874 DOI: 10.1021/ja201088k  1
2011 Wilson MC, Nam SJ, Gulder TA, Kauffman CA, Jensen PR, Fenical W, Moore BS. Structure and biosynthesis of the marine streptomycete ansamycin ansalactam A and its distinctive branched chain polyketide extender unit. Journal of the American Chemical Society. 133: 1971-7. PMID 21247149 DOI: 10.1021/ja109226s  1
2011 Jaspars M, Moore B, Piel J, Cox R. Editorial: Marine Natural Products themed issue Natural Product Reports. 28: 181. PMID 21229158 DOI: 10.1039/c0np90037k  1
2011 Mo S, Kim DH, Lee JH, Park JW, Basnet DB, Ban YH, Yoo YJ, Chen SW, Park SR, Choi EA, Kim E, Jin YY, Lee SK, Park JY, Liu Y, ... ... Moore BS, et al. Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues. Journal of the American Chemical Society. 133: 976-85. PMID 21175203 DOI: 10.1021/ja108399b  1
2011 Lane AL, Moore BS. A sea of biosynthesis: marine natural products meet the molecular age. Natural Product Reports. 28: 411-28. PMID 21170424 DOI: 10.1039/c0np90032j  1
2011 Eustáquio AS, Nam SJ, Penn K, Lechner A, Wilson MC, Fenical W, Jensen PR, Moore BS. The discovery of salinosporamide K from the marine bacterium "Salinispora pacifica" by genome mining gives insight into pathway evolution. Chembiochem : a European Journal of Chemical Biology. 12: 61-4. PMID 21154492 DOI: 10.1002/cbic.201000564  1
2011 Moore B, Kelly R. Happy new year from natural product reports Natural Product Reports. 28: 9-10. DOI: 10.1039/c0np90027c  1
2010 Roberts AA, Ryan KS, Moore BS, Gulder TA. Total (bio)synthesis: strategies of nature and of chemists. Topics in Current Chemistry. 297: 149-203. PMID 21495259 DOI: 10.1007/128_2010_79  1
2010 Gulder TA, Moore BS. Salinosporamide natural products: Potent 20 S proteasome inhibitors as promising cancer chemotherapeutics. Angewandte Chemie (International Ed. in English). 49: 9346-67. PMID 20927786 DOI: 10.1002/anie.201000728  1
2010 Mahlstedt S, Fielding EN, Moore BS, Walsh CT. Prephenate decarboxylases: a new prephenate-utilizing enzyme family that performs nonaromatizing decarboxylation en route to diverse secondary metabolites. Biochemistry. 49: 9021-3. PMID 20863139 DOI: 10.1021/bi101457h  1
2010 Kale AJ, McGlinchey RP, Moore BS. Characterization of 5-chloro-5-deoxy-D-ribose 1-dehydrogenase in chloroethylmalonyl coenzyme A biosynthesis: substrate and reaction profiling. The Journal of Biological Chemistry. 285: 33710-7. PMID 20736169 DOI: 10.1074/jbc.M110.153833  1
2010 Wilson MC, Gulder TA, Mahmud T, Moore BS. Shared biosynthesis of the saliniketals and rifamycins in Salinispora arenicola is controlled by the sare1259-encoded cytochrome P450. Journal of the American Chemical Society. 132: 12757-65. PMID 20726561 DOI: 10.1021/ja105891a  1
2010 Werneburg M, Busch B, He J, Richter ME, Xiang L, Moore BS, Roth M, Dahse HM, Hertweck C. Exploiting enzymatic promiscuity to engineer a focused library of highly selective antifungal and antiproliferative aureothin analogues. Journal of the American Chemical Society. 132: 10407-13. PMID 20662518 DOI: 10.1021/ja102751h  1
2010 Cardellina JH, Moore BS. Journal of Natural Products: Editorial Journal of Natural Products. 73: 301-302. PMID 20141160 DOI: 10.1021/np100045f  1
2010 Eustáquio AS, O'Hagan D, Moore BS. Engineering fluorometabolite production: fluorinase expression in Salinispora tropica Yields Fluorosalinosporamide. Journal of Natural Products. 73: 378-82. PMID 20085308 DOI: 10.1021/np900719u  1
2010 Schultz AW, Lewis CA, Luzung MR, Baran PS, Moore BS. Functional characterization of the cyclomarin/cyclomarazine prenyltransferase CymD directs the biosynthesis of unnatural cyclic peptides. Journal of Natural Products. 73: 373-7. PMID 20055491 DOI: 10.1021/np9006876  1
2010 Moore BS, Crews P. Overview and Introduction Comprehensive Natural Products Ii: Chemistry and Biology. 2: 1-4.  1
2009 Nett M, Ikeda H, Moore BS. Genomic basis for natural product biosynthetic diversity in the actinomycetes. Natural Product Reports. 26: 1362-84. PMID 19844637 DOI: 10.1039/b817069j  1
2009 Nett M, Gulder TA, Kale AJ, Hughes CC, Moore BS. Function-oriented biosynthesis of beta-lactone proteasome inhibitors in Salinispora tropica. Journal of Medicinal Chemistry. 52: 6163-7. PMID 19746976 DOI: 10.1021/jm901098m  1
2009 Deng H, McMahon SA, Eustáquio AS, Moore BS, Naismith JH, O'Hagan D. Mechanistic insights into water activation in SAM hydroxide adenosyltransferase (duf-62). Chembiochem : a European Journal of Chemical Biology. 10: 2455-9. PMID 19739191 DOI: 10.1002/cbic.200900369  1
2009 Liu Y, Hazzard C, Eustáquio AS, Reynolds KA, Moore BS. Biosynthesis of salinosporamides from alpha,beta-unsaturated fatty acids: implications for extending polyketide synthase diversity. Journal of the American Chemical Society. 131: 10376-7. PMID 19601645 DOI: 10.1021/ja9042824  1
2009 Eustáquio AS, McGlinchey RP, Liu Y, Hazzard C, Beer LL, Florova G, Alhamadsheh MM, Lechner A, Kale AJ, Kobayashi Y, Reynolds KA, Moore BS. Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine. Proceedings of the National Academy of Sciences of the United States of America. 106: 12295-300. PMID 19590008 DOI: 10.1073/pnas.0901237106  1
2009 Gulder TA, Moore BS. Chasing the treasures of the sea - bacterial marine natural products. Current Opinion in Microbiology. 12: 252-60. PMID 19481972 DOI: 10.1016/j.mib.2009.05.002  1
2009 Penn K, Jenkins C, Nett M, Udwary DW, Gontang EA, McGlinchey RP, Foster B, Lapidus A, Podell S, Allen EE, Moore BS, Jensen PR. Genomic islands link secondary metabolism to functional adaptation in marine Actinobacteria. The Isme Journal. 3: 1193-203. PMID 19474814 DOI: 10.1038/ismej.2009.58  1
2009 Liu WT, Ng J, Meluzzi D, Bandeira N, Gutierrez M, Simmons TL, Schultz AW, Linington RG, Moore BS, Gerwick WH, Pevzner PA, Dorrestein PC. Interpretation of tandem mass spectra obtained from cyclic nonribosomal peptides. Analytical Chemistry. 81: 4200-9. PMID 19413302 DOI: 10.1021/ac900114t  1
2009 Winter JM, Moore BS. Exploring the chemistry and biology of vanadium-dependent haloperoxidases. The Journal of Biological Chemistry. 284: 18577-81. PMID 19363038 DOI: 10.1074/jbc.R109.001602  1
2009 Ryan KS, Moore BS. Alkaloid biosynthesis takes root. Nature Chemical Biology. 5: 140-1. PMID 19219013 DOI: 10.1038/nchembio0309-140  1
2009 Kalaitzis JA, Cheng Q, Thomas PM, Kelleher NL, Moore BS. In vitro biosynthesis of unnatural enterocin and wailupemycin polyketides. Journal of Natural Products. 72: 469-72. PMID 19215142 DOI: 10.1021/np800598t  1
2009 Winter JM, Jansma AL, Handel TM, Moore BS. Formation of the pyridazine natural product azamerone by biosynthetic rearrangement of an aryl diazoketone. Angewandte Chemie (International Ed. in English). 48: 767-70. PMID 19072974 DOI: 10.1002/anie.200805140  1
2009 Nett M, Moore BS. Exploration and engineering of biosynthetic pathways in the marine actinomycete Salinispora tropica Pure and Applied Chemistry. 81: 1075-1084. DOI: 10.1351/PAC-CON-08-08-08  1
2008 Moore BS. Extending the biosynthetic repertoire in ribosomal peptide assembly. Angewandte Chemie (International Ed. in English). 47: 9386-8. PMID 18846537 DOI: 10.1002/anie.200803868  1
2008 Eustáquio AS, Härle J, Noel JP, Moore BS. S-Adenosyl-L-methionine hydrolase (adenosine-forming), a conserved bacterial and archaeal protein related to SAM-dependent halogenases. Chembiochem : a European Journal of Chemical Biology. 9: 2215-9. PMID 18720493 DOI: 10.1002/cbic.200800341  1
2008 Worthington AS, Hur GH, Meier JL, Cheng Q, Moore BS, Burkart MD. Probing the compatibility of type II ketosynthase-carrier protein partners. Chembiochem : a European Journal of Chemical Biology. 9: 2096-103. PMID 18666307 DOI: 10.1002/cbic.200800198  1
2008 Moore BS, Eustáquio AS, McGlinchey RP. Advances in and applications of proteasome inhibitors. Current Opinion in Chemical Biology. 12: 434-40. PMID 18656549 DOI: 10.1016/j.cbpa.2008.06.033  1
2008 McGlinchey RP, Nett M, Eustáquio AS, Asolkar RN, Fenical W, Moore BS. Engineered biosynthesis of antiprotealide and other unnatural salinosporamide proteasome inhibitors. Journal of the American Chemical Society. 130: 7822-3. PMID 18512922 DOI: 10.1021/ja8029398  1
2008 Eustáquio AS, Moore BS. Mutasynthesis of fluorosalinosporamide, a potent and reversible inhibitor of the proteasome. Angewandte Chemie (International Ed. in English). 47: 3936-8. PMID 18407559 DOI: 10.1002/anie.200800177  1
2008 Schultz AW, Oh DC, Carney JR, Williamson RT, Udwary DW, Jensen PR, Gould SJ, Fenical W, Moore BS. Biosynthesis and structures of cyclomarins and cyclomarazines, prenylated cyclic peptides of marine actinobacterial origin. Journal of the American Chemical Society. 130: 4507-16. PMID 18331040 DOI: 10.1021/ja711188x  1
2008 McGlinchey RP, Nett M, Moore BS. Unraveling the biosynthesis of the sporolide cyclohexenone building block. Journal of the American Chemical Society. 130: 2406-7. PMID 18232689 DOI: 10.1021/ja710488m  1
2008 Eustáquio AS, Pojer F, Noel JP, Moore BS. Discovery and characterization of a marine bacterial SAM-dependent chlorinase. Nature Chemical Biology. 4: 69-74. PMID 18059261 DOI: 10.1038/nchembio.2007.56  1
2007 Cheng Q, Xiang L, Izumikawa M, Meluzzi D, Moore BS. Enzymatic total synthesis of enterocin polyketides. Nature Chemical Biology. 3: 557-8. PMID 17704772 DOI: 10.1038/nchembio.2007.22  1
2007 Udwary DW, Zeigler L, Asolkar RN, Singan V, Lapidus A, Fenical W, Jensen PR, Moore BS. Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica. Proceedings of the National Academy of Sciences of the United States of America. 104: 10376-81. PMID 17563368 DOI: 10.1073/pnas.0700962104  1
2007 Winter JM, Moffitt MC, Zazopoulos E, McAlpine JB, Dorrestein PC, Moore BS. Molecular basis for chloronium-mediated meroterpene cyclization: cloning, sequencing, and heterologous expression of the napyradiomycin biosynthetic gene cluster. The Journal of Biological Chemistry. 282: 16362-8. PMID 17392281 DOI: 10.1074/jbc.M611046200  1
2007 Beer LL, Moore BS. Biosynthetic convergence of salinosporamides A and B in the marine actinomycete Salinispora tropica. Organic Letters. 9: 845-8. PMID 17274624 DOI: 10.1021/ol063102o  1
2007 Moffitt MC, Louie GV, Bowman ME, Pence J, Noel JP, Moore BS. Discovery of two cyanobacterial phenylalanine ammonia lyases: kinetic and structural characterization. Biochemistry. 46: 1004-12. PMID 17240984 DOI: 10.1021/bi061774g  1
2006 Louie GV, Bowman ME, Moffitt MC, Baiga TJ, Moore BS, Noel JP. Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases. Chemistry & Biology. 13: 1327-38. PMID 17185228 DOI: 10.1016/j.chembiol.2006.11.011  0.44
2006 Hicks LM, Moffitt MC, Beer LL, Moore BS, Kelleher NL. Structural characterization of in vitro and in vivo intermediates on the loading module of microcystin synthetase. Acs Chemical Biology. 1: 93-102. PMID 17163649 DOI: 10.1021/cb500007v  1
2006 Song L, Barona-Gomez F, Corre C, Xiang L, Udwary DW, Austin MB, Noel JP, Moore BS, Challis GL. Type III polyketide synthase beta-ketoacyl-ACP starter unit and ethylmalonyl-CoA extender unit selectivity discovered by Streptomyces coelicolor genome mining. Journal of the American Chemical Society. 128: 14754-5. PMID 17105255 DOI: 10.1021/ja065247w  1
2006 Austin MB, Saito T, Bowman ME, Haydock S, Kato A, Moore BS, Kay RR, Noel JP. Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase. Nature Chemical Biology. 2: 494-502. PMID 16906151 DOI: 10.1038/nchembio811  1
2006 Moore BS. Biosynthesis of marine natural products: macroorganisms (Part B). Natural Product Reports. 23: 615-29. PMID 16874392 DOI: 10.1039/b508781n  1
2006 Izumikawa M, Cheng Q, Moore BS. Priming type II polyketide synthases via a type II nonribosomal peptide synthetase mechanism. Journal of the American Chemical Society. 128: 1428-9. PMID 16448095 DOI: 10.1021/ja0559707  1
2005 Moore BS. Biosynthesis of marine natural products: microorganisms (Part A). Natural Product Reports. 22: 580-93. PMID 16193157 DOI: 10.1039/b404737k  1
2005 Xiang L, Moore BS. Biochemical characterization of a prokaryotic phenylalanine ammonia lyase. Journal of Bacteriology. 187: 4286-9. PMID 15937191 DOI: 10.1128/JB.187.12.4286-4289.2005  1
2005 Moore BS, Kalaitzis JA, Xiang L. Exploiting marine actinomycete biosynthetic pathways for drug discovery. Antonie Van Leeuwenhoek. 87: 49-57. PMID 15726291 DOI: 10.1007/s10482-004-6541-0  1
2005 Zhao B, Guengerich FP, Bellamine A, Lamb DC, Izumikawa M, Lei L, Podust LM, Sundaramoorthy M, Kalaitzis JA, Reddy LM, Kelly SL, Moore BS, Stec D, Voehler M, Falck JR, et al. Binding of two flaviolin substrate molecules, oxidative coupling, and crystal structure of Streptomyces coelicolor A3(2) cytochrome P450 158A2. The Journal of Biological Chemistry. 280: 11599-607. PMID 15659395 DOI: 10.1074/jbc.M410933200  1
2004 Xiang L, Kalaitzis JA, Moore BS. EncM, a versatile enterocin biosynthetic enzyme involved in Favorskii oxidative rearrangement, aldol condensation, and heterocycle-forming reactions. Proceedings of the National Academy of Sciences of the United States of America. 101: 15609-14. PMID 15505225 DOI: 10.1073/pnas.0405508101  1
2004 Kalaitzis JA, Moore BS. Heterologous biosynthesis of truncated hexaketides derived from the actinorhodin polyketide synthase. Journal of Natural Products. 67: 1419-22. PMID 15332868 DOI: 10.1021/np0499564  1
2004 Garcia-Bernardo J, Xiang L, Hong H, Moore BS, Leadlay PF. Engineered biosynthesis of phenyl-substituted polyketides. Chembiochem : a European Journal of Chemical Biology. 5: 1129-31. PMID 15300838 DOI: 10.1002/cbic.200400007  1
2004 Austin MB, Izumikawa M, Bowman ME, Udwary DW, Ferrer JL, Moore BS, Noel JP. Crystal structure of a bacterial type III polyketide synthase and enzymatic control of reactive polyketide intermediates. The Journal of Biological Chemistry. 279: 45162-74. PMID 15265863 DOI: 10.1074/jbc.M406567200  1
2004 Hertweck C, Xiang L, Kalaitzis JA, Cheng Q, Palzer M, Moore BS. Context-dependent behavior of the enterocin iterative polyketide synthase; a new model for ketoreduction. Chemistry & Biology. 11: 461-8. PMID 15123240 DOI: 10.1016/j.chembiol.2004.03.018  1
2004 Becker JE, Moore RE, Moore BS. Cloning, sequencing, and biochemical characterization of the nostocyclopeptide biosynthetic gene cluster: molecular basis for imine macrocyclization. Gene. 325: 35-42. PMID 14697508 DOI: 10.1016/j.gene.2003.09.034  1
2003 Kalaitzis JA, Hamano Y, Nilsen G, Moore BS. Biosynthesis and structural revision of neomarinone. Organic Letters. 5: 4449-52. PMID 14602022 DOI: 10.1021/ol035748b  0.64
2003 Izumikawa M, Shipley PR, Hopke JN, O'Hare T, Xiang L, Noel JP, Moore BS. Expression and characterization of the type III polyketide synthase 1,3,6,8-tetrahydroxynaphthalene synthase from Streptomyces coelicolor A3(2). Journal of Industrial Microbiology & Biotechnology. 30: 510-5. PMID 12905073 DOI: 10.1007/s10295-003-0075-8  1
2003 Kalaitzis JA, Izumikawa M, Xiang L, Hertweck C, Moore BS. Mutasynthesis of enterocin and wailupemycin analogues. Journal of the American Chemical Society. 125: 9290-1. PMID 12889947 DOI: 10.1021/ja035973o  1
2003 Hoffmann D, Hevel JM, Moore RE, Moore BS. Sequence analysis and biochemical characterization of the nostopeptolide A biosynthetic gene cluster from Nostoc sp. GSV224. Gene. 311: 171-80. PMID 12853152 DOI: 10.1016/S0378-1119(03)00587-0  1
2003 Xiang L, Moore BS. Characterization of benzoyl coenzyme A biosynthesis genes in the enterocin-producing bacterium "Streptomyces maritimus". Journal of Bacteriology. 185: 399-404. PMID 12511484  0.64
2002 Moore BS, Hertweck C, Hopke JN, Izumikawa M, Kalaitzis JA, Nilsen G, O'Hare T, Piel J, Shipley PR, Xiang L, Austin MB, Noel JP. Plant-like biosynthetic pathways in bacteria: from benzoic acid to chalcone. Journal of Natural Products. 65: 1956-62. PMID 12502351 DOI: 10.1021/np020230m  1
2002 Xiang L, Moore BS. Inactivation, complementation, and heterologous expression of encP, a novel bacterial phenylalanine ammonia-lyase gene. The Journal of Biological Chemistry. 277: 32505-9. PMID 12082112 DOI: 10.1074/jbc.M204171200  0.64
2002 Moore BS, Hertweck C. Biosynthesis and attachment of novel bacterial polyketide synthase starter units. Natural Product Reports. 19: 70-99. PMID 11902441  1
2002 Xiang L, Kalaitzis JA, Nilsen G, Chen L, Moore BS. Mutational analysis of the enterocin favorskii biosynthetic rearrangement. Organic Letters. 4: 957-60. PMID 11893195  0.64
2001 Hertweck C, Jarvis AP, Xiang L, Moore BS, Oldham NJ. A mechanism of benzoic acid biosynthesis in plants and bacteria that mirrors fatty acid beta-oxidation. Chembiochem : a European Journal of Chemical Biology. 2: 784-6. PMID 11948863 DOI: 10.1002/1439-7633(20011001)2:10<784::AID-CBIC784>3.0.CO;2-K  1
2000 Moore BS, Piel J. Engineering biodiversity with type II polyketide synthase genes. Antonie Van Leeuwenhoek. 78: 391-8. PMID 11386362 DOI: 10.1023/A:1010273224820  1
2000 Piel J, Hertweck C, Shipley PR, Hunt DM, Newman MS, Moore BS. Cloning, sequencing and analysis of the enterocin biosynthesis gene cluster from the marine isolate 'Streptomyces maritimus': evidence for the derailment of an aromatic polyketide synthase. Chemistry & Biology. 7: 943-55. PMID 11137817 DOI: 10.1016/S1074-5521(00)00044-2  1
1999 Yu TW, Shen Y, Doi-Katayama Y, Tang L, Park C, Moore BS, Richard Hutchinson C, Floss HG. Direct evidence that the rifamycin polyketide synthase assembles polyketide chains processively. Proceedings of the National Academy of Sciences of the United States of America. 96: 9051-6. PMID 10430893 DOI: 10.1073/pnas.96.16.9051  1
1999 Shen Y, Yoon P, Yu TW, Floss HG, Hopwood D, Moore BS. Ectopic expression of the minimal whiE polyketide synthase generates a library of aromatic polyketides of diverse sizes and shapes. Proceedings of the National Academy of Sciences of the United States of America. 96: 3622-7. PMID 10097087 DOI: 10.1073/pnas.96.7.3622  1
1997 Moore BS, Walker K, Tornus I, Handa S, Poralla K, Floss HG. Biosynthetic Studies of omega-Cycloheptyl Fatty Acids in Alicyclobacillus cycloheptanicus. Formation of Cycloheptanecarboxylic Acid from Phenylacetic Acid. The Journal of Organic Chemistry. 62: 2173-2185. PMID 11671526  1
1995 Moore BS, Floss HG, Poralla K. Three new omega-cycloheptyl fatty acids from Alicyclobacillus cycloheptanicus and their biosynthetic interrelationships. Journal of Natural Products. 58: 590-3. PMID 7623036  1
1994 Moore BS, Floss HG. Biosynthetic studies on the origin of the cyclohexanecarboxylic acid moiety of ansatrienin A and omega-cyclohexyl fatty acids. Journal of Natural Products. 57: 382-6. PMID 8201312  1
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