Floyd E. Romesberg - Publications

Affiliations: 
1998- Chemistry Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Website:
http://www.scripps.edu/romesberg/

203 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Zhou AX, Dong X, Romesberg FE. Transcription and Reverse Transcription of an Expanded Genetic Alphabet In Vitro and in a Semisynthetic Organism. Journal of the American Chemical Society. PMID 33118814 DOI: 10.1021/jacs.0c09230  1
2020 Tan YX, Peters DS, Walsh SI, Holcomb M, Santos-Martins D, Forli S, Romesberg FE. Initial Analysis of the Arylomycin D Antibiotics. Journal of Natural Products. PMID 32614583 DOI: 10.1021/Acs.Jnatprod.9B01174  1
2020 Fischer EC, Hashimoto K, Zhang Y, Feldman AW, Dien VT, Karadeema RJ, Adhikary R, Ledbetter MP, Krishnamurthy R, Romesberg FE. New codons for efficient production of unnatural proteins in a semisynthetic organism. Nature Chemical Biology. PMID 32251411 DOI: 10.1038/S41589-020-0507-Z  1
2020 Ledbetter MP, Craig JM, Karadeema RJ, Noakes MT, Kim HC, Abell SJ, Huang JR, Anderson BA, Krishnamurthy R, Gundlach JH, Romesberg FE. Nanopore Sequencing of an Expanded Genetic Alphabet Reveals High-Fidelity Replication of a Predominantly Hydrophobic Unnatural Base Pair. Journal of the American Chemical Society. PMID 31985216 DOI: 10.1021/Jacs.9B09808  1
2020 Shao Q, Chen T, Sheng K, Liu Z, Zhang Z, Romesberg FE. Selection of Aptamers with Large Hydrophobic 2'-Substituents. Journal of the American Chemical Society. PMID 31961667 DOI: 10.1021/Jacs.9B10538  1
2019 Zhou AX, Sheng K, Feldman AW, Romesberg FE. Progress toward Eukaryotic Semisynthetic Organisms: Translation of Unnatural Codons. Journal of the American Chemical Society. PMID 31841336 DOI: 10.1021/Jacs.9B09080  1
2019 Adhikary R, Zimmermann J, Stanfield RL, Wilson IA, Yu W, Oda M, Romesberg FE. Structure and Dynamics of Stacking Interactions in an Antibody Binding Site. Biochemistry. PMID 31243995 DOI: 10.2210/Pdb6M87/Pdb  1
2019 Feldman AW, Dien VT, Karadeema RJ, Fischer EC, You Y, Anderson BA, Krishnamurthy R, Chen JS, Li L, Romesberg FE. Optimization of Replication, Transcription, and Translation in a Semi-Synthetic Organism. Journal of the American Chemical Society. PMID 31241334 DOI: 10.1021/Jacs.9B02075  1
2019 Dien VT, Holcomb M, Romesberg FE. Eight-Letter DNA. Biochemistry. PMID 31117391 DOI: 10.1021/Acs.Biochem.9B00274  1
2019 Ledbetter MP, Malyshev DA, Romesberg FE. Site-Specific Labeling of DNA via PCR with an Expanded Genetic Alphabet. Methods in Molecular Biology (Clifton, N.J.). 1973: 193-212. PMID 31016704 DOI: 10.1007/978-1-4939-9216-4_13  1
2018 Walsh SI, Peters DS, Smith PA, Craney A, Dix MM, Cravatt BF, Romesberg FE. The inhibition of protein secretion in and sub-MIC effects of arylomycin antibiotics. Antimicrobial Agents and Chemotherapy. PMID 30420476 DOI: 10.1128/Aac.01253-18  1
2018 Dien VT, Holcomb M, Feldman AW, Fischer EC, Dwyer TJ, Romesberg FE. Progress Toward a Semi-Synthetic Organism with an Unrestricted Expanded Genetic Alphabet. Journal of the American Chemical Society. PMID 30418780 DOI: 10.1021/Jacs.8B08416  1
2018 Ledbetter MP, Romesberg FE. Editorial overview: Expanding the genetic alphabet and code. Current Opinion in Chemical Biology. PMID 30270151 DOI: 10.1016/J.Cbpa.2018.09.007  1
2018 Dien VT, Morris SE, Karadeema RJ, Romesberg FE. Expansion of the genetic code via expansion of the genetic alphabet. Current Opinion in Chemical Biology. 46: 196-202. PMID 30205312 DOI: 10.1016/J.Cbpa.2018.08.009  1
2018 Yeh CH, Walsh SI, Craney A, Tabor MG, Voica AF, Adhikary R, Morris SE, Romesberg FE. Optimization of a β-Lactam Scaffold for Antibacterial Activity via the Inhibition of Bacterial Type I Signal Peptidase. Acs Medicinal Chemistry Letters. 9: 376-380. PMID 29670704 DOI: 10.1021/Acsmedchemlett.8B00064  1
2018 Zhang Y, Romesberg FE. Semisynthetic Organisms with Expanded Genetic Codes. Biochemistry. PMID 29624384 DOI: 10.1021/Acs.Biochem.8B00013  1
2018 Peters D, Romesberg FE, Baran PS. Scalable Access to Arylomycins via C-H Functionalization logic. Journal of the American Chemical Society. PMID 29381350 DOI: 10.1021/Jacs.8B00087  1
2018 Feldman AW, Fischer EC, Ledbetter MP, Liao JY, Chaput JC, Romesberg FE. A Tool for the Import of Natural and Unnatural Nucleoside Triphosphates into Bacteria. Journal of the American Chemical Society. PMID 29338214 DOI: 10.1021/Jacs.7B11404  1
2018 Ledbetter MP, Karadeema RJ, Romesberg FE. Reprograming the Replisome of a Semisynthetic Organism for the Expansion of the Genetic Alphabet. Journal of the American Chemical Society. PMID 29309130 DOI: 10.1021/Jacs.7B11488  1
2017 Liu Z, Chen T, Romesberg FE. Evolved polymerases facilitate selection of fully 2'-OMe-modified aptamers. Chemical Science. 8: 8179-8182. PMID 29568464 DOI: 10.1039/C7Sc03747C  1
2017 Holcomb M, Adhikary R, Zimmermann J, Romesberg FE. Topological Evidence of Previously Overlooked Ni+1-H···Ni H-Bonds and Their Contribution to Protein Structure and Stability. The Journal of Physical Chemistry. A. PMID 29260873 DOI: 10.1021/Acs.Jpca.7B11013  1
2017 Craney A, Romesberg FE. Stable Signal Peptides and the Response to Secretion Stress in Staphylococcus aureus. Mbio. 8. PMID 29233892 DOI: 10.1128/Mbio.01507-17  1
2017 Feldman AW, Romesberg FE. Expansion of the Genetic Alphabet: A Chemist's Approach to Synthetic Biology. Accounts of Chemical Research. PMID 29198111 DOI: 10.1021/Acs.Accounts.7B00403  1
2017 Zhang Y, Ptacin JL, Fischer EC, Aerni HR, Caffaro CE, San Jose K, Feldman AW, Turner CR, Romesberg FE. A semi-synthetic organism that stores and retrieves increased genetic information. Nature. 551: 644-647. PMID 29189780 DOI: 10.1038/Nature24659  1
2017 Chen T, Romesberg FE. A Method for the Exponential Synthesis of RNA: Introducing the Polymerase Chain Transcription (PCT) Reaction. Biochemistry. PMID 28930440 DOI: 10.1021/Acs.Biochem.7B00846  1
2017 Chen T, Romesberg FE. Enzymatic synthesis, amplification, and application of DNA with a functionalized backbone. Angewandte Chemie (International Ed. in English). PMID 28914996 DOI: 10.1002/Anie.201707367  1
2017 Feldman AW, Romesberg FE. In Vivo Structure-Activity Relationships and Optimization of an Unnatural Base Pair for Replication in a Semi-Synthetic Organism. Journal of the American Chemical Society. PMID 28796508 DOI: 10.1021/Jacs.7B03540  1
2017 Feldman AW, Ledbetter MP, Zhang Y, Romesberg FE. Reply to Hettinger: Hydrophobic unnatural base pairs and the expansion of the genetic alphabet. Proceedings of the National Academy of Sciences of the United States of America. 114: E6478-E6479. PMID 28768812 DOI: 10.1073/Pnas.1708259114  1
2017 Chen T, Romesberg FE. Polymerase Chain Transcription: Exponential Synthesis of RNA and Modified RNA. Journal of the American Chemical Society. PMID 28715205 DOI: 10.1021/Jacs.7B03981  1
2017 Morris SE, Feldman AW, Romesberg FE. Synthetic Biology Parts for the Storage of Increased Genetic Information in Cells. Acs Synthetic Biology. PMID 28654252 DOI: 10.1021/Acssynbio.7B00115  1
2017 Adhikary R, Tan YX, Liu J, Zimmermann J, Holcomb M, Yvellez C, Dawson PE, Romesberg FE. Conformational Heterogeneity and DNA Recognition by the Morphogen Bicoid. Biochemistry. PMID 28547993 DOI: 10.1021/Acs.Biochem.7B00255  1
2017 Thirunavukarasu D, Chen T, Liu Z, Hongdilokkul N, Romesberg FE. Selection of 2'-Fluoro-Modified Aptamers with Optimized Properties. Journal of the American Chemical Society. PMID 28218835 DOI: 10.1021/Jacs.6B13132  1
2017 Feldman AW, Dien VT, Romesberg FE. Chemical Stabilization of Unnatural Nucleotide Triphosphates for the in Vivo Expansion of the Genetic Alphabet. Journal of the American Chemical Society. PMID 28170246 DOI: 10.1021/Jacs.6B12731  1
2017 Zhang Y, Lamb BM, Feldman AW, Zhou AX, Lavergne T, Li L, Romesberg FE. A semisynthetic organism engineered for the stable expansion of the genetic alphabet. Proceedings of the National Academy of Sciences of the United States of America. PMID 28115716 DOI: 10.1073/Pnas.1616443114  1
2017 Adhikary R, Zimmermann J, Romesberg FE. Transparent Window Vibrational Probes for the Characterization of Proteins With High Structural and Temporal Resolution. Chemical Reviews. PMID 28106985 DOI: 10.1021/Acs.Chemrev.6B00625  1
2016 Romesberg FE, Craney A. Discovery of novel antibacterials. Bioorganic & Medicinal Chemistry. 24: 6225-6226. PMID 27932231 DOI: 10.1016/J.Bmc.2016.11.046  1
2016 Walsh SI, Craney A, Romesberg FE. Not just an antibiotic target: Exploring the role of type I signal peptidase in bacterial virulence. Bioorganic & Medicinal Chemistry. PMID 27769673 DOI: 10.1016/J.Bmc.2016.09.048  1
2016 Chen T, Hongdilokkul N, Liu Z, Thirunavukarasu D, Romesberg FE. The expanding world of DNA and RNA. Current Opinion in Chemical Biology. 34: 80-87. PMID 27565457 DOI: 10.1016/J.Cbpa.2016.08.001  1
2016 Chen T, Hongdilokkul N, Liu Z, Adhikary R, Tsuen SS, Romesberg FE. Evolution of thermophilic DNA polymerases for the recognition and amplification of C2'-modified DNA. Nature Chemistry. 8: 556-562. PMID 27219699 DOI: 10.1038/Nchem.2493  1
2016 Lavergne T, Lamichhane R, Malyshev DA, Li Z, Li L, Sperling E, Williamson JR, Millar DP, Romesberg FE. FRET Characterization of Complex Conformational Changes in a Large 16S Ribosomal RNA Fragment Site-Specifically Labeled Using Unnatural Base Pairs. Acs Chemical Biology. PMID 26942998 DOI: 10.1021/Acschembio.5B00952  1
2015 Adhikary R, Zimmermann J, Dawson PE, Romesberg FE. Temperature Dependence of CN and SCN IR Absorptions Facilitates Their Interpretation and Use as Probes of Proteins. Analytical Chemistry. PMID 26523838 DOI: 10.1021/Acs.Analchem.5B03437  1
2015 Malyshev DA, Romesberg FE. The Expanded Genetic Alphabet. Angewandte Chemie (International Ed. in English). 54: 11930-44. PMID 26304162 DOI: 10.1002/Anie.201502890  1
2015 Craney A, Dix MM, Adhikary R, Cravatt BF, Romesberg FE. An Alternative Terminal Step of the General Secretory Pathway in Staphylococcus aureus. Mbio. 6. PMID 26286693 DOI: 10.1128/Mbio.01178-15  1
2015 Craney A, Romesberg FE. The inhibition of type I bacterial signal peptidase: Biological consequences and therapeutic potential. Bioorganic & Medicinal Chemistry Letters. 25: 4761-6. PMID 26276537 DOI: 10.1016/J.Bmcl.2015.07.072  1
2015 Steed DB, Liu J, Wasbrough E, Miller L, Halasohoris S, Miller J, Somerville B, Hershfield JR, Romesberg FE. Origins of Yersinia pestis Sensitivity to the Arylomycin Antibiotics and the Inhibition of Type I Signal Peptidase. Antimicrobial Agents and Chemotherapy. 59: 3887-98. PMID 25896690 DOI: 10.1128/Aac.00181-15  1
2015 Adhikary R, Yu W, Oda M, Walker RC, Chen T, Stanfield RL, Wilson IA, Zimmermann J, Romesberg FE. Adaptive mutations alter antibody structure and dynamics during affinity maturation. Biochemistry. 54: 2085-93. PMID 25756188 DOI: 10.1021/Bi501417Q  1
2015 Craney A, Romesberg FE. A Putative Cro-Like Repressor Contributes to Arylomycin Resistance in Staphylococcus aureus. Antimicrobial Agents and Chemotherapy. 59: 3066-74. PMID 25753642 DOI: 10.1128/Aac.04597-14  1
2015 Craney A, Romesberg FE. The inhibition of type I bacterial signal peptidase: Biological consequences and therapeutic potential Bioorganic and Medicinal Chemistry Letters. DOI: 10.1016/j.bmcl.2015.07.072  1
2015 Malyshev DA, Romesberg FE. The Expanded Genetic Alphabet Angewandte Chemie - International Edition. DOI: 10.1002/anie.201502890  1
2014 Rodriguez RA, Barrios Steed D, Kawamata Y, Su S, Smith PA, Steed TC, Romesberg FE, Baran PS. Axinellamines as broad-spectrum antibacterial agents: scalable synthesis and biology. Journal of the American Chemical Society. 136: 15403-13. PMID 25328977 DOI: 10.1021/Ja508632Y  1
2014 Adhikary R, Zimmermann J, Liu J, Forrest RP, Janicki TD, Dawson PE, Corcelli SA, Romesberg FE. Evidence of an unusual N-H···N hydrogen bond in proteins. Journal of the American Chemical Society. 136: 13474-7. PMID 25226114 DOI: 10.1021/Ja503107H  1
2014 Dhami K, Malyshev DA, Ordoukhanian P, Kubelka T, Hocek M, Romesberg FE. Systematic exploration of a class of hydrophobic unnatural base pairs yields multiple new candidates for the expansion of the genetic alphabet. Nucleic Acids Research. 42: 10235-44. PMID 25122747 DOI: 10.1093/Nar/Gku715  1
2014 Malyshev DA, Dhami K, Lavergne T, Chen T, Dai N, Foster JM, Corrêa IR, Romesberg FE. A semi-synthetic organism with an expanded genetic alphabet. Nature. 509: 385-8. PMID 24805238 DOI: 10.1038/Nature13314  1
2014 Adhikary R, Zimmermann J, Dawson PE, Romesberg FE. IR probes of protein microenvironments: utility and potential for perturbation. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 15: 849-53. PMID 24519759 DOI: 10.1002/Cphc.201400017  1
2014 Chen T, Romesberg FE. Directed polymerase evolution. Febs Letters. 588: 219-29. PMID 24211837 DOI: 10.1016/J.Febslet.2013.10.040  1
2014 Li L, Degardin M, Lavergne T, Malyshev DA, Dhami K, Ordoukhanian P, Romesberg FE. Natural-like replication of an unnatural base pair for the expansion of the genetic alphabet and biotechnology applications. Journal of the American Chemical Society. 136: 826-9. PMID 24152106 DOI: 10.1021/Ja408814G  1
2014 Zimmermann J, Romesberg FE. Carbon-deuterium bonds as non-perturbative infrared probes of protein dynamics, electrostatics, heterogeneity, and folding. Methods in Molecular Biology (Clifton, N.J.). 1084: 101-19. PMID 24061918 DOI: 10.1007/978-1-62703-658-0_6  1
2013 Betz K, Malyshev DA, Lavergne T, Welte W, Diederichs K, Romesberg FE, Marx A. Structural insights into DNA replication without hydrogen bonds. Journal of the American Chemical Society. 135: 18637-43. PMID 24283923 DOI: 10.1021/Ja409609J  1
2013 Li Z, Lavergne T, Malyshev DA, Zimmermann J, Adhikary R, Dhami K, Ordoukhanian P, Sun Z, Xiang J, Romesberg FE. Site-specifically arraying small molecules or proteins on DNA using an expanded genetic alphabet. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 14205-9. PMID 24026962 DOI: 10.1002/Chem.201302496  1
2013 Liu J, Smith PA, Steed DB, Romesberg F. Efforts toward broadening the spectrum of arylomycin antibiotic activity. Bioorganic & Medicinal Chemistry Letters. 23: 5654-9. PMID 24012184 DOI: 10.1016/J.Bmcl.2013.08.026  1
2013 Adhikary R, Zimmermann J, Liu J, Dawson PE, Romesberg FE. Experimental characterization of electrostatic and conformational heterogeneity in an SH3 domain. The Journal of Physical Chemistry. B. 117: 13082-9. PMID 23834285 DOI: 10.1021/Jp402772X  1
2013 Lavergne T, Degardin M, Malyshev DA, Quach HT, Dhami K, Ordoukhanian P, Romesberg FE. Expanding the scope of replicable unnatural DNA: stepwise optimization of a predominantly hydrophobic base pair. Journal of the American Chemical Society. 135: 5408-19. PMID 23547847 DOI: 10.1021/Ja312148Q  1
2013 Harris DA, Romesberg FE. SpsB Signal Peptidase Handbook of Proteolytic Enzymes. 3: 3501-3508. DOI: 10.1016/B978-0-12-382219-2.00776-6  1
2012 Quinto-Alemany D, Canerina-Amaro A, Hernández-Abad LG, Machín F, Romesberg FE, Gil-Lamaignere C. Yeasts acquire resistance secondary to antifungal drug treatment by adaptive mutagenesis. Plos One. 7: e42279. PMID 22860105 DOI: 10.1371/Journal.Pone.0042279  1
2012 Smith PA, Romesberg FE. Mechanism of action of the arylomycin antibiotics and effects of signal peptidase I inhibition. Antimicrobial Agents and Chemotherapy. 56: 5054-60. PMID 22802255 DOI: 10.1128/Aac.00785-12  1
2012 Malyshev DA, Dhami K, Quach HT, Lavergne T, Ordoukhanian P, Torkamani A, Romesberg FE. Efficient and sequence-independent replication of DNA containing a third base pair establishes a functional six-letter genetic alphabet. Proceedings of the National Academy of Sciences of the United States of America. 109: 12005-10. PMID 22773812 DOI: 10.1073/Pnas.1205176109  1
2012 Adhikary R, Yu W, Oda M, Zimmermann J, Romesberg FE. Protein dynamics and the diversity of an antibody response. The Journal of Biological Chemistry. 287: 27139-47. PMID 22685303 DOI: 10.1074/Jbc.M112.372698  1
2012 Betz K, Malyshev DA, Lavergne T, Welte W, Diederichs K, Dwyer TJ, Ordoukhanian P, Romesberg FE, Marx A. KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry. Nature Chemical Biology. 8: 612-4. PMID 22660438 DOI: 10.1038/Nchembio.966  1
2012 Yu W, Dawson PE, Zimmermann J, Romesberg FE. Carbon-deuterium bonds as probes of protein thermal unfolding. The Journal of Physical Chemistry. B. 116: 6397-403. PMID 22625650 DOI: 10.1021/Jp303521T  1
2012 Schallenberger MA, Niessen S, Shao C, Fowler BJ, Romesberg FE. Type I signal peptidase and protein secretion in Staphylococcus aureus. Journal of Bacteriology. 194: 2677-86. PMID 22447899 DOI: 10.1128/Jb.00064-12  1
2012 Lavergne T, Malyshev DA, Romesberg FE. Major groove substituents and polymerase recognition of a class of predominantly hydrophobic unnatural base pairs. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 1231-9. PMID 22190386 DOI: 10.1002/Chem.201102066  1
2012 Tan YX, Romesberg FE. Latent antibiotics and the potential of the arylomycins for broad-spectrum antibacterial activity Medchemcomm. 3: 916-925. DOI: 10.1039/C2Md20043K  1
2011 Liu J, Luo C, Smith PA, Chin JK, Page MG, Paetzel M, Romesberg FE. Synthesis and characterization of the arylomycin lipoglycopeptide antibiotics and the crystallographic analysis of their complex with signal peptidase. Journal of the American Chemical Society. 133: 17869-77. PMID 21999324 DOI: 10.1021/Ja207318N  1
2011 Seo YJ, Malyshev DA, Lavergne T, Ordoukhanian P, Romesberg FE. Site-specific labeling of DNA and RNA using an efficiently replicated and transcribed class of unnatural base pairs. Journal of the American Chemical Society. 133: 19878-88. PMID 21981600 DOI: 10.1021/Ja207907D  1
2011 Nicolaou KC, Ellery SP, Rivas F, Saye K, Rogers E, Workinger TJ, Schallenberger M, Tawatao R, Montero A, Hessell A, Romesberg F, Carson D, Burton D. Synthesis and biological evaluation of 2',4'- and 3',4'-bridged nucleoside analogues. Bioorganic & Medicinal Chemistry. 19: 5648-69. PMID 21840722 DOI: 10.1016/J.Bmc.2011.07.022  1
2011 Zimmermann J, Thielges MC, Seo YJ, Dawson PE, Romesberg FE. Cyano groups as probes of protein microenvironments and dynamics. Angewandte Chemie (International Ed. in English). 50: 8333-7. PMID 21780257 DOI: 10.1002/Anie.201101016  1
2011 Roberts TC, Schallenberger MA, Liu J, Smith PA, Romesberg FE. Initial efforts toward the optimization of arylomycins for antibiotic activity. Journal of Medicinal Chemistry. 54: 4954-63. PMID 21630667 DOI: 10.1021/Jm1016126  1
2011 Roberts TC, Smith PA, Romesberg FE. Synthesis and biological characterization of arylomycin B antibiotics. Journal of Natural Products. 74: 956-61. PMID 21545107 DOI: 10.1021/Np200163G  1
2011 Smith PA, Powers ME, Roberts TC, Romesberg FE. In vitro activities of arylomycin natural-product antibiotics against Staphylococcus epidermidis and other coagulase-negative staphylococci. Antimicrobial Agents and Chemotherapy. 55: 1130-4. PMID 21189343 DOI: 10.1128/Aac.01459-10  1
2011 Powers ME, Smith PA, Roberts TC, Fowler BJ, King CC, Trauger SA, Siuzdak G, Romesberg FE. Type I signal peptidase and protein secretion in Staphylococcus epidermidis. Journal of Bacteriology. 193: 340-8. PMID 21075926 DOI: 10.1128/Jb.01052-10  1
2011 Zimmermann J, Thielges MC, Yu W, Dawson PE, Romesberg FE. Carbon-deuterium bonds as site-specific and nonperturbative probes for time-resolved studies of protein dynamics and folding Journal of Physical Chemistry Letters. 2: 412-416. DOI: 10.1021/Jz200012H  1
2011 Zimmermann J, Thielges MC, Yu W, Romesberg FE. Protein Dynamics and the Evolution of Novel Protein Function Protein Engineering Handbook, Volume 1 & Volume 2. 1: 147-185. DOI: 10.1002/9783527634026.ch6  1
2010 Smith PA, Roberts TC, Romesberg FE. Broad-spectrum antibiotic activity of the arylomycin natural products is masked by natural target mutations. Chemistry & Biology. 17: 1223-31. PMID 21095572 DOI: 10.1016/J.Chembiol.2010.09.009  1
2010 Schallenberger MA, Newhouse T, Baran PS, Romesberg FE. The psychotrimine natural products have antibacterial activity against Gram-positive bacteria and act via membrane disruption. The Journal of Antibiotics. 63: 685-7. PMID 20924383 DOI: 10.1038/Ja.2010.107  1
2010 Malyshev DA, Pfaff DA, Ippoliti SI, Hwang GT, Dwyer TJ, Romesberg FE. Solution structure, mechanism of replication, and optimization of an unnatural base pair. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 12650-9. PMID 20859962 DOI: 10.1002/Chem.201000959  1
2010 Leconte AM, Patel MP, Sass LE, McInerney P, Jarosz M, Kung L, Bowers JL, Buzby PR, Efcavitch JW, Romesberg FE. Directed evolution of DNA polymerases for next-generation sequencing. Angewandte Chemie (International Ed. in English). 49: 5921-4. PMID 20629059 DOI: 10.1002/Anie.201001607  1
2010 Chen D, Lei L, Lu C, Flores R, DeLisa MP, Roberts TC, Romesberg FE, Zhong G. Secretion of the chlamydial virulence factor CPAF requires the Sec-dependent pathway. Microbiology (Reading, England). 156: 3031-40. PMID 20522495 DOI: 10.1099/Mic.0.040527-0  1
2010 Zimmermann J, Romesberg FE, Brooks CL, Thorpe IF. Molecular description of flexibility in an antibody combining site. The Journal of Physical Chemistry. B. 114: 7359-70. PMID 20455589 DOI: 10.1021/Jp906421V  1
2010 Li B, Smith P, Horvath DJ, Romesberg FE, Justice SS. SOS regulatory elements are essential for UPEC pathogenesis. Microbes and Infection / Institut Pasteur. 12: 662-8. PMID 20435157 DOI: 10.1016/J.Micinf.2010.04.009  1
2010 Weinkam P, Zimmermann J, Romesberg FE, Wolynes PG. The folding energy landscape and free energy excitations of cytochrome c. Accounts of Chemical Research. 43: 652-60. PMID 20143816 DOI: 10.1021/Ar9002703  1
2009 Malyshev DA, Seo YJ, Ordoukhanian P, Romesberg FE. PCR with an expanded genetic alphabet. Journal of the American Chemical Society. 131: 14620-1. PMID 19788296 DOI: 10.1021/Ja906186F  1
2009 Seo YJ, Romesberg FE. Major groove derivatization of an unnatural base pair. Chembiochem : a European Journal of Chemical Biology. 10: 2394-400. PMID 19722235 DOI: 10.1002/Cbic.200900413  1
2009 Hwang GT, Hari Y, Romesberg FE. The effects of unnatural base pairs and mispairs on DNA duplex stability and solvation. Nucleic Acids Research. 37: 4757-63. PMID 19515938 DOI: 10.1093/Nar/Gkp467  1
2009 Zimmermann J, Gundogdu K, Cremeens ME, Bandaria JN, Hwang GT, Thielges MC, Cheatum CM, Romesberg FE. Efforts toward developing probes of protein dynamics: vibrational dephasing and relaxation of carbon-deuterium stretching modes in deuterated leucine. The Journal of Physical Chemistry. B. 113: 7991-4. PMID 19441845 DOI: 10.1021/Jp900516C  1
2009 Harris DA, Powers ME, Romesberg FE. Synthesis and biological evaluation of penem inhibitors of bacterial signal peptidase. Bioorganic & Medicinal Chemistry Letters. 19: 3787-90. PMID 19427205 DOI: 10.1016/J.Bmcl.2009.04.034  1
2009 Thielges MC, Zimmermann J, Romesberg FE. Direct observation of ligand dynamics in cytochrome c. Journal of the American Chemical Society. 131: 6054-5. PMID 19361220 DOI: 10.1021/Ja810155S  1
2009 Seo YJ, Matsuda S, Romesberg FE. Transcription of an expanded genetic alphabet. Journal of the American Chemical Society. 131: 5046-7. PMID 19351201 DOI: 10.1021/Ja9006996  1
2009 Cremeens ME, Zimmermann J, Yu W, Dawson PE, Romesberg FE. Direct observation of structural heterogeneity in a beta-sheet. Journal of the American Chemical Society. 131: 5726-7. PMID 19351132 DOI: 10.1021/Ja900505E  1
2009 Groff D, Thielges MC, Cellitti S, Schultz PG, Romesberg FE. Efforts toward the direct experimental characterization of enzyme microenvironments: tyrosine100 in dihydrofolate reductase. Angewandte Chemie (International Ed. in English). 48: 3478-81. PMID 19347910 DOI: 10.1002/Anie.200806239  1
2009 Naraharisetty SR, Kasyanenko VM, Zimmermann J, Thielges MC, Romesberg FE, Rubtsov IV. C-D modes of deuterated side chain of leucine as structural reporters via dual-frequency two-dimensional infrared spectroscopy. The Journal of Physical Chemistry. B. 113: 4940-6. PMID 19298041 DOI: 10.1021/Jp8112446  1
2009 Thielges MC, Zimmermann J, Dawson PE, Romesberg FE. The determinants of stability and folding in evolutionarily diverged cytochromes c. Journal of Molecular Biology. 388: 159-67. PMID 19268474 DOI: 10.1016/J.Jmb.2009.02.059  1
2009 Seo YJ, Hwang GT, Ordoukhanian P, Romesberg FE. Optimization of an unnatural base pair toward natural-like replication. Journal of the American Chemical Society. 131: 3246-52. PMID 19256568 DOI: 10.1021/Ja807853M  1
2009 Weinkam P, Romesberg FE, Wolynes PG. Chemical frustration in the protein folding landscape: grand canonical ensemble simulations of cytochrome c. Biochemistry. 48: 2394-402. PMID 19199810 DOI: 10.1021/Bi802293M  1
2008 Weinkam P, Zimmermann J, Sagle LB, Matsuda S, Dawson PE, Wolynes PG, Romesberg FE. Characterization of alkaline transitions in ferricytochrome c using carbon-deuterium infrared probes. Biochemistry. 47: 13470-80. PMID 19035653 DOI: 10.1021/Bi801223N  1
2008 Hari Y, Hwang GT, Leconte AM, Joubert N, Hocek M, Romesberg FE. Optimization of the pyridyl nucleobase scaffold for polymerase recognition and unnatural base pair replication. Chembiochem : a European Journal of Chemical Biology. 9: 2796-9. PMID 19012285 DOI: 10.1002/Cbic.200800577  1
2008 Hwang GT, Romesberg FE. Unnatural substrate repertoire of A, B, and X family DNA polymerases. Journal of the American Chemical Society. 130: 14872-82. PMID 18847263 DOI: 10.1021/Ja803833H  1
2008 Mapp A, Romesberg FE. Several novel approaches to developing therapeutics that target both bacterial and human proteins. Current Opinion in Chemical Biology. 12: 387-8. PMID 18707019 DOI: 10.1016/J.Cbpa.2008.08.003  1
2008 Thielges MC, Zimmermann J, Yu W, Oda M, Romesberg FE. Exploring the energy landscape of antibody-antigen complexes: protein dynamics, flexibility, and molecular recognition. Biochemistry. 47: 7237-47. PMID 18549243 DOI: 10.1021/Bi800374Q  1
2008 Thielges MC, Case DA, Romesberg FE. Carbon-deuterium bonds as probes of dihydrofolate reductase. Journal of the American Chemical Society. 130: 6597-603. PMID 18412341 DOI: 10.1021/Ja0779607  1
2008 Lis ET, O'Neill BM, Gil-Lamaignere C, Chin JK, Romesberg FE. Identification of pathways controlling DNA damage induced mutation in Saccharomyces cerevisiae. Dna Repair. 7: 801-10. PMID 18400565 DOI: 10.1016/J.Dnarep.2008.02.007  1
2008 Leconte AM, Hwang GT, Matsuda S, Capek P, Hari Y, Romesberg FE. Discovery, characterization, and optimization of an unnatural base pair for expansion of the genetic alphabet. Journal of the American Chemical Society. 130: 2336-43. PMID 18217762 DOI: 10.1021/Ja078223D  1
2007 Heideker J, Lis ET, Romesberg FE. Phosphatases, DNA damage checkpoints and checkpoint deactivation. Cell Cycle (Georgetown, Tex.). 6: 3058-64. PMID 18075314 DOI: 10.4161/Cc.6.24.5100  1
2007 Roberts TC, Smith PA, Cirz RT, Romesberg FE. Structural and initial biological analysis of synthetic arylomycin A2. Journal of the American Chemical Society. 129: 15830-8. PMID 18052061 DOI: 10.1021/Ja073340U  1
2007 Cirz RT, Romesberg FE. Controlling mutation: intervening in evolution as a therapeutic strategy. Critical Reviews in Biochemistry and Molecular Biology. 42: 341-54. PMID 17917871 DOI: 10.1080/10409230701597741  1
2007 Smith PA, Romesberg FE. Combating bacteria and drug resistance by inhibiting mechanisms of persistence and adaptation. Nature Chemical Biology. 3: 549-56. PMID 17710101 DOI: 10.1038/Nchembio.2007.27  1
2007 Matsuda S, Fillo JD, Henry AA, Rai P, Wilkens SJ, Dwyer TJ, Geierstanger BH, Wemmer DE, Schultz PG, Spraggon G, Romesberg FE. Efforts toward expansion of the genetic alphabet: structure and replication of unnatural base pairs. Journal of the American Chemical Society. 129: 10466-73. PMID 17685517 DOI: 10.1021/Ja072276D  1
2007 Hwang GT, Leconte AM, Romesberg FE. Polymerase recognition and stability of fluoro-substituted pyridone nucleobase analogues. Chembiochem : a European Journal of Chemical Biology. 8: 1606-11. PMID 17647205 DOI: 10.1002/Cbic.200700308  1
2007 Goodman MF, Scharff MD, Romesberg FE. AID-initiated purposeful mutations in immunoglobulin genes. Advances in Immunology. 94: 127-55. PMID 17560274 DOI: 10.1016/S0065-2776(06)94005-X  1
2007 O'Neill BM, Szyjka SJ, Lis ET, Bailey AO, Yates JR, Aparicio OM, Romesberg FE. Pph3-Psy2 is a phosphatase complex required for Rad53 dephosphorylation and replication fork restart during recovery from DNA damage. Proceedings of the National Academy of Sciences of the United States of America. 104: 9290-5. PMID 17517611 DOI: 10.1073/Pnas.0703252104  1
2007 Matsuda S, Leconte AM, Romesberg FE. Minor groove hydrogen bonds and the replication of unnatural base pairs. Journal of the American Chemical Society. 129: 5551-7. PMID 17411040 DOI: 10.1021/Ja068282B  1
2007 Cirz RT, Jones MB, Gingles NA, Minogue TD, Jarrahi B, Peterson SN, Romesberg FE. Complete and SOS-mediated response of Staphylococcus aureus to the antibiotic ciprofloxacin. Journal of Bacteriology. 189: 531-9. PMID 17085555 DOI: 10.1128/Jb.01464-06  1
2006 Leconte AM, Romesberg FE. Chemical biology: a broader take on DNA. Nature. 444: 553-5. PMID 17136078 DOI: 10.1038/444553A  1
2006 Sagle LB, Zimmermann J, Dawson PE, Romesberg FE. Direct and high resolution characterization of cytochrome c equilibrium folding. Journal of the American Chemical Society. 128: 14232-3. PMID 17076477 DOI: 10.1021/Ja065179D  1
2006 Kim Y, Leconte AM, Hari Y, Romesberg FE. Stability and polymerase recognition of pyridine nucleobase analogues: role of minor-groove H-bond acceptors. Angewandte Chemie (International Ed. in English). 45: 7809-12. PMID 17075934 DOI: 10.1002/Anie.200602579  1
2006 Kinnaman CS, Cremeens ME, Romesberg FE, Corcelli SA. Infrared line shape of an alpha-carbon deuterium-labeled amino acid. Journal of the American Chemical Society. 128: 13334-5. PMID 17031927 DOI: 10.1021/Ja064468Z  1
2006 Cirz RT, O'Neill BM, Hammond JA, Head SR, Romesberg FE. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Journal of Bacteriology. 188: 7101-10. PMID 17015649 DOI: 10.1128/Jb.00807-06  1
2006 Zimmermann J, Oakman EL, Thorpe IF, Shi X, Abbyad P, Brooks CL, Boxer SG, Romesberg FE. Antibody evolution constrains conformational heterogeneity by tailoring protein dynamics. Proceedings of the National Academy of Sciences of the United States of America. 103: 13722-7. PMID 16954202 DOI: 10.1073/Pnas.0603282103  1
2006 Leconte AM, Romesberg FE. Amplify this! DNA and RNA get a third base pair. Nature Methods. 3: 667-8. PMID 16929309 DOI: 10.1038/Nmeth0906-667  1
2006 Cirz RT, Gingles N, Romesberg FE. Side effects may include evolution. Nature Medicine. 12: 890-1. PMID 16892033 DOI: 10.1038/Nm0806-890  1
2006 Sagle LB, Zimmermann J, Matsuda S, Dawson PE, Romesberg FE. Redox-coupled dynamics and folding in cytochrome c. Journal of the American Chemical Society. 128: 7909-15. PMID 16771505 DOI: 10.1021/Ja060851S  1
2006 Leconte AM, Matsuda S, Hwang GT, Romesberg FE. Efforts towards expansion of the genetic alphabet: pyridone and methyl pyridone nucleobases. Angewandte Chemie (International Ed. in English). 45: 4326-9. PMID 16733840 DOI: 10.1002/Anie.200601272  1
2006 Leconte AM, Matsuda S, Romesberg FE. An efficiently extended class of unnatural base pairs. Journal of the American Chemical Society. 128: 6780-1. PMID 16719445 DOI: 10.1021/Ja060853C  1
2006 Lis ET, Romesberg FE. Role of Doa1 in the Saccharomyces cerevisiae DNA damage response. Molecular and Cellular Biology. 26: 4122-33. PMID 16705165 DOI: 10.1128/Mcb.01640-05  1
2006 Matsuda S, Henry AA, Romesberg FE. Optimization of unnatural base pair packing for polymerase recognition. Journal of the American Chemical Society. 128: 6369-75. PMID 16683801 DOI: 10.1021/Ja057575M  1
2006 Cremeens ME, Fujisaki H, Zhang Y, Zimmermann J, Sagle LB, Matsuda S, Dawson PE, Straub JE, Romesberg FE. Efforts toward developing direct probes of protein dynamics. Journal of the American Chemical Society. 128: 6028-9. PMID 16669659 DOI: 10.1021/Ja061328G  1
2006 Hwang GT, Romesberg FE. Substituent effects on the pairing and polymerase recognition of simple unnatural base pairs. Nucleic Acids Research. 34: 2037-45. PMID 16617144 DOI: 10.1093/Nar/Gkl049  1
2006 Chin JK, Bashkirov VI, Heyer WD, Romesberg FE. Esc4/Rtt107 and the control of recombination during replication. Dna Repair. 5: 618-28. PMID 16569515 DOI: 10.1016/J.Dnarep.2006.02.005  1
2006 Cirz RT, Romesberg FE. Induction and inhibition of ciprofloxacin resistance-conferring mutations in hypermutator bacteria. Antimicrobial Agents and Chemotherapy. 50: 220-5. PMID 16377689 DOI: 10.1128/Aac.50.1.220-225.2006  1
2006 Bayley H, Romesberg F. From therapeutic nucleic acids to redox hydrogels: the diverse world of biopolymers Current Opinion in Chemical Biology. 10: 598-600. DOI: 10.1016/J.Cbpa.2006.10.028  1
2005 Romesberg FE. Efforts to expand the genetic code. Nucleic Acids Symposium Series (2004). 89-90. PMID 17150647 DOI: 10.1093/nass/49.1.89  1
2005 Dupradeau FY, Case DA, Yu C, Jimenez R, Romesberg FE. Differential solvation and tautomer stability of a model base pair within the minor and major grooves of DNA. Journal of the American Chemical Society. 127: 15612-7. PMID 16262427 DOI: 10.1021/Ja054607X  1
2005 Leconte AM, Chen L, Romesberg FE. Polymerase evolution: efforts toward expansion of the genetic code. Journal of the American Chemical Society. 127: 12470-1. PMID 16144377 DOI: 10.1021/Ja053322H  1
2005 Henry AA, Romesberg FE. The evolution of DNA polymerases with novel activities. Current Opinion in Biotechnology. 16: 370-7. PMID 16006114 DOI: 10.1016/J.Copbio.2005.06.008  1
2005 Cirz RT, Chin JK, Andes DR, de Crécy-Lagard V, Craig WA, Romesberg FE. Inhibition of mutation and combating the evolution of antibiotic resistance. Plos Biology. 3: e176. PMID 15869329 DOI: 10.1371/Journal.Pbio.0030176  1
2005 Holmberg RC, Henry AA, Romesberg FE. Directed evolution of novel polymerases. Biomolecular Engineering. 22: 39-49. PMID 15857782 DOI: 10.1016/J.Bioeng.2004.12.001  1
2004 O'Neill BM, Hanway D, Winzeler EA, Romesberg FE. Coordinated functions of WSS1, PSY2 and TOF1 in the DNA damage response. Nucleic Acids Research. 32: 6519-30. PMID 15598824 DOI: 10.1093/Nar/Gkh994  1
2004 Matsuda S, Romesberg FE. Optimization of interstrand hydrophobic packing interactions within unnatural DNA base pairs. Journal of the American Chemical Society. 126: 14419-27. PMID 15521761 DOI: 10.1021/Ja047291M  1
2004 Henry AA, Jimenez R, Hanway D, Romesberg FE. Preliminary characterization of light harvesting in E. coli DNA photolyase. Chembiochem : a European Journal of Chemical Biology. 5: 1088-94. PMID 15300832 DOI: 10.1002/Cbic.200400013  1
2004 Henry AA, Olsen AG, Matsuda S, Yu C, Geierstanger BH, Romesberg FE. Efforts to expand the genetic alphabet: identification of a replicable unnatural DNA self-pair. Journal of the American Chemical Society. 126: 6923-31. PMID 15174862 DOI: 10.1021/Ja049961U  1
2004 Sagle LB, Zimmermann J, Dawson PE, Romesberg FE. A high-resolution probe of protein folding. Journal of the American Chemical Society. 126: 3384-5. PMID 15025440 DOI: 10.1021/Ja049890Z  1
2004 Jimenez R, Salazar G, Yin J, Joo T, Romesberg FE. Protein dynamics and the immunological evolution of molecular recognition. Proceedings of the National Academy of Sciences of the United States of America. 101: 3803-8. PMID 15001706 DOI: 10.1073/Pnas.0305745101  1
2004 Fa M, Radeghieri A, Henry AA, Romesberg FE. Expanding the substrate repertoire of a DNA polymerase by directed evolution. Journal of the American Chemical Society. 126: 1748-54. PMID 14871106 DOI: 10.1021/Ja038525P  1
2004 Romesberg FE, Schowen RL. Isotope effects and quantum tunneling in enzyme-catalyzed hydrogen transfer. Part I. The experimental basis Advances in Physical Organic Chemistry. 39: 27-77. DOI: 10.1016/S0065-3160(04)39002-7  1
2003 Henry AA, Romesberg FE. Beyond A, C, G and T: augmenting nature's alphabet. Current Opinion in Chemical Biology. 7: 727-33. PMID 14644182 DOI: 10.1016/J.Cbpa.2003.10.011  1
2003 Henry AA, Yu C, Romesberg FE. Determinants of unnatural nucleobase stability and polymerase recognition. Journal of the American Chemical Society. 125: 9638-46. PMID 12904030 DOI: 10.1021/Ja035398O  1
2003 Romesberg FE. Multidisciplinary experimental approaches to characterizing biomolecular dynamics. Chembiochem : a European Journal of Chemical Biology. 4: 563-71. PMID 12851924 DOI: 10.1002/Cbic.200300572  1
2003 Matsuda S, Henry AA, Schultz PG, Romesberg FE. The effect of minor-groove hydrogen-bond acceptors and donors on the stability and replication of four unnatural base pairs. Journal of the American Chemical Society. 125: 6134-9. PMID 12785844 DOI: 10.1021/Ja034099W  1
2003 Jimenez R, Salazar G, Baldridge KK, Romesberg FE. Flexibility and molecular recognition in the immune system. Proceedings of the National Academy of Sciences of the United States of America. 100: 92-7. PMID 12518056 DOI: 10.1073/Pnas.262411399  1
2003 Jimenez R, Romesberg FE. Photon echo spectroscopy as a probe of dynamics in the immune system Proceedings of Spie - the International Society For Optical Engineering. 4978: 112-121. DOI: 10.1117/12.478604  1
2003 Wang H, Zhang H, Abou-Zied OK, Yu C, Romesberg FE, Glasbeek M. Femtosecond fluorescence upconversion studies of excited-state proton-transfer dynamics in 2-(2′-hydroxyphenyl)benzoxazole (HBO) in liquid solution and DNA Chemical Physics Letters. 367: 599-608. DOI: 10.1016/S0009-2614(02)01741-4  1
2003 Jimenez R, Romesberg FE. Measurement of protein flexibility using photon echo spectroscopy Osa Trends in Optics and Photonics Series. 88: 1753-1754.  1
2002 Romesberg FE, Yu C, Matsuda S, Henry AA. Development of a universal nucleobase and modified nucleobases for expanding the genetic code. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. Unit 1.5. PMID 18428883 DOI: 10.1002/0471142700.Nc0105S10  1
2002 Wu Y, Fa M, Tae EL, Schultz PG, Romesberg FE. Enzymatic phosphorylation of unnatural nucleosides. Journal of the American Chemical Society. 124: 14626-30. PMID 12465973 DOI: 10.1021/Ja028050M  1
2002 Yu C, Henry AA, Romesberg FE, Schultz PG. Polymerase recognition of unnatural base pairs. Angewandte Chemie (International Ed. in English). 41: 3841-4. PMID 12386865 DOI: 10.1002/1521-3773(20021018)41:20<3841::Aid-Anie3841>3.0.Co;2-Q  1
2002 Hanway D, Chin JK, Xia G, Oshiro G, Winzeler EA, Romesberg FE. Previously uncharacterized genes in the UV- and MMS-induced DNA damage response in yeast. Proceedings of the National Academy of Sciences of the United States of America. 99: 10605-10. PMID 12149442 DOI: 10.1073/Pnas.152264899  1
2002 Xia G, Chen L, Sera T, Fa M, Schultz PG, Romesberg FE. Directed evolution of novel polymerase activities: mutation of a DNA polymerase into an efficient RNA polymerase. Proceedings of the National Academy of Sciences of the United States of America. 99: 6597-602. PMID 12011423 DOI: 10.1073/Pnas.102577799  1
2002 Chin JK, Jimenez R, Romesberg FE. Protein dynamics and cytochrome c: correlations between ligand vibrations and redox activity. Journal of the American Chemical Society. 124: 1846-7. PMID 11866585 DOI: 10.1021/Ja012312N  1
2002 Berger M, Luzzi SD, Henry AA, Romesberg FE. Stability and selectivity of unnatural DNA with five-membered-ring nucleobase analogues. Journal of the American Chemical Society. 124: 1222-6. PMID 11841290 DOI: 10.1021/Ja012090T  1
2002 Jimenez R, Romesberg FE. Excited state dynamics and heterogeneity of folded and unfolded states of cytochrome c Journal of Physical Chemistry B. 106: 9172-9180. DOI: 10.1021/Jp0209648  1
2002 Abou-Zied OK, Jimenez R, Thompson EHZ, Millar DP, Romesberg FE. Solvent-dependent photoinduced tautomerization of 2-(2′-hydroxyphenyl)benzoxazole Journal of Physical Chemistry A. 106: 3665-3672. DOI: 10.1021/Jp013915O  1
2002 Jimenez R, Case DA, Romesberg FE. Flexibility of an antibody binding site measured with photon echo spectroscopy Journal of Physical Chemistry B. 106: 1090-1103. DOI: 10.1021/Jp013110G  1
2001 Tae EL, Wu Y, Xia G, Schultz PG, Romesberg FE. Efforts toward expansion of the genetic alphabet: replication of DNA with three base pairs. Journal of the American Chemical Society. 123: 7439-40. PMID 11472182 DOI: 10.1021/Ja010731E  1
2001 Abou-Zied OK, Jimenez R, Romesberg FE. Tautomerization dynamics of a model base pair in DNA. Journal of the American Chemical Society. 123: 4613-4. PMID 11457253 DOI: 10.1021/Ja003647S  1
2001 Chin JK, Jimenez R, Romesberg FE. Direct observation of protein vibrations by selective incorporation of spectroscopically observable carbon-deuterium bonds in cytochrome c. Journal of the American Chemical Society. 123: 2426-7. PMID 11456893 DOI: 10.1021/Ja0033741  1
2000 Berger M, Ogawa AK, McMinn DL, Wu Y, Schultz PG, Romesberg FE. Stable and Selective Hybridization of Oligonucleotides with Unnatural Hydrophobic Bases This work was supported by the National Institutes of Health (GM 60005 to F.E.R.) and the Skaggs Institute for Chemical Biology (F.E.R. and P.G.S.). A.K.O. thanks the National Institutes of Health for a postdoctoral fellowship (F32 GM19833-01). Angewandte Chemie (International Ed. in English). 39: 2940-2942. PMID 11028017 DOI: 10.1002/1521-3773(20000818)39:16<2940::Aid-Anie2940>3.0.Co;2-#  1
2000 Berger M, Wu Y, Ogawa AK, McMinn DL, Schultz PG, Romesberg FE. Universal bases for hybridization, replication and chain termination. Nucleic Acids Research. 28: 2911-4. PMID 10908353 DOI: 10.1093/Nar/28.15.2911  1
2000 Ogawa AK, Wu Y, McMinn DL, Liu J, Schultz PG, Romesberg FE. Efforts toward the expansion of the genetic alphabet: Information storage and replication with unnatural hydrophobic base pairs Journal of the American Chemical Society. 122: 3274-3287. DOI: 10.1021/Ja9940064  1
2000 Meggers E, Holland PL, Tolman WB, Romesberg FE, Schultz PG. A novel copper-mediated DNA base pair [6] Journal of the American Chemical Society. 122: 10714-10715. DOI: 10.1021/Ja0025806  1
2000 Ogawa AK, Abou-Zied OK, Tsui V, Jimenez R, Case DA, Romesberg FE. A phototautomerizable model DNA base pair Journal of the American Chemical Society. 122: 9917-9920. DOI: 10.1021/Ja001778N  1
2000 Ogawa AK, Wu Y, Berger M, Schultz PG, Romesberg FE. Rational design of an unnatural base pair with increased kinetic selectivity [14] Journal of the American Chemical Society. 122: 8803-8804. DOI: 10.1021/Ja001450U  1
2000 Wu Y, Ogawa AK, Berger M, McMinn DL, Schultz PG, Romesberg FE. Efforts toward expansion of the genetic alphabet: Optimization of interbase hydrophobic interactions Journal of the American Chemical Society. 122: 7621-7632. DOI: 10.1021/Ja0009931  1
2000 Shulman H, Makarov C, Ogawa AK, Romesberg F, Keinan E. Chemically reactive immunogens lead to functional convergence of the immune response Journal of the American Chemical Society. 122: X. DOI: 10.1021/ja000616o  1
2000 Berger M, Ogawa AK, McMinn D, Wu Y, Schultz PG, Romesberg FE. Stabile und selektive Hybridisierung von Oligonucleotiden unter Verwendung nichtnatürlicher hydrophober Basen Angewandte Chemie. 112: 3069-3071. DOI: 10.1002/1521-3757(20000818)112:16<3069::Aid-Ange3069>3.0.Co;2-K  1
2000 Shulman H, Makarov C, Ogawa AK, Romesberg F, Keinan E. Chemically reactive immunogens lead to functional convergence of the immune response Journal of the American Chemical Society. 122: X.  1
1999 Romesberg FE, Schultz PG. A mutational study of a Diels-Alderase catalytic antibody. Bioorganic & Medicinal Chemistry Letters. 9: 1741-4. PMID 10406634 DOI: 10.1016/S0960-894X(99)00281-4  1
1999 McMinn DL, Ogawa AK, Wu Y, Liu J, Schultz PG, Romesberg FE. Efforts toward expansion of the genetic alphabet: DNA polymerase recognition of a highly stable, self-pairing hydrophobic base [10] Journal of the American Chemical Society. 121: 11585-11586. DOI: 10.1021/Ja9925150  1
1998 Romesberg FE, Santarsiero BD, Spiller B, Yin J, Barnes D, Schultz PG, Stevens RC. Structural and kinetic evidence for strain in biological catalysis. Biochemistry. 37: 14404-9. PMID 9772166 DOI: 10.1021/Bi981578C  1
1998 Romesberg FE, Spiller B, Schultz PG, Stevens RC. Immunological origins of binding and catalysis in a Diels-Alderase antibody. Science (New York, N.Y.). 279: 1929-33. PMID 9506942 DOI: 10.1126/Science.279.5358.1929  1
1998 Blackwood ME, Rush TS, Romesberg F, Schultz PG, Spiro TG. Alternative modes of substrate distortion in enzyme and antibody catalyzed ferrochelation reactions. Biochemistry. 37: 779-82. PMID 9457047 DOI: 10.1021/Bi972616F  1
1998 Romesberg FE, Flanagan ME, Uno T, Schultz PG. Mechanistic studies of an antibody-catalyzed elimination reaction Journal of the American Chemical Society. 120: 5160-5167. DOI: 10.1021/ja9738992  1
1997 Remenar JF, Lucht BL, Kruglyak D, Romesberg FE, Gilchirst JH, Collum DB. Lithium 2,2,6,6-Tetramethylpiperidide and Lithium 2,2,4,6,6-Pentamethylpiperidide: Influence of TMEDA and Related Chelating Ligands on the Solution Structures. Characterization of Higher Cyclic Oligomers, Cyclic Dimers, Open Dimers, and Monomers Journal of Organic Chemistry. 62: 5748-5754. DOI: 10.1021/Jo970520L  1
1996 Stevens RC, Hsieh-Wilson LC, Santarsiero BD, Wedemayer GJ, Spiller B, Wang LH, Barnes D, Ulrich HD, Patten PA, Romesberg FE, Schultz PG. Structural Studies of Catalytic Antibodies Israel Journal of Chemistry. 36: 121-132. DOI: 10.1002/Ijch.199600018  1
1996 Stevens RC, Hsieh-Wilson LC, Santarsiero BD, Wedemayer GJ, Spiller B, Wang LH, Barnes D, Ulrich HD, Patten PA, Romesberg FE, Schlutz PG. Structural studies of catalytic antibodies Israel Journal of Chemistry. 36: 121-132.  1
1995 Ulrich HD, Patten PA, Yang PL, Romesberg FE, Schultz PG. Expression studies of catalytic antibodies. Proceedings of the National Academy of Sciences of the United States of America. 92: 11907-11. PMID 8524873 DOI: 10.1073/Pnas.92.25.11907  1
1995 Romesberg FE, Collum DB. Mechanism of lithium dialkylamide-mediated ketone and imine deprotonations: An MNDO study of monomer and open dimer pathways Journal of the American Chemical Society. 117: 2166-2178. DOI: 10.1021/Ja00113A006  1
1994 Romesberg FE, Collum DB. Lithium dialkylamide mixed aggregation: An NMR spectroscopic study of the influence of hexamethylphosphoramide (HMPA) Journal of the American Chemical Society. 116: 9198-9202. DOI: 10.1021/Ja00099A039  1
1994 Romesberg FE, Collum DB. Lithium dialkylamide mixed aggregation: MNDO computational study of salt and solvent dependencies Journal of the American Chemical Society. 116: 9187-9197. DOI: 10.1021/Ja00099A038  1
1993 Sakuma K, Gilchrist JH, Romesberg FE, Cajthaml CE, Collum DB. Lithium bis(2-adamantyl)amide: Structure and reactivity of an extremely hindered lithium dialkylamide Tetrahedron Letters. 34: 5213-5216. DOI: 10.1016/S0040-4039(00)73955-4  1
1993 Romesberg FE, Bernstein MP, Gilchrist JH, Harrison AT, Fuller DJ, Collum DB. Structure of lithium hexamethyldisilazide (LiHMDS) in the presence of hexamethylphosphoramide (HMPA). Spectroscopic and computational studies of monomers, dimers, and triple ions Journal of the American Chemical Society. 115: 3475-3483.  1
1992 Bernstein MP, Romesberg FE, Fuller DJ, Harrison AT, Collum DB, Liu QY, Williard PG. Structure and reactivity of lithium diisopropylamide in the presence of N,N,N′,N′-tetramethylethylenediamine Journal of the American Chemical Society. 114: 5100-5110. DOI: 10.1021/Ja00039A022  1
1992 Romesberg FE, Collum DB. Determination of structures of solvated lithium dialkylamides by semiempirical (MNDO) methods. Comparison of theory and experiment Journal of the American Chemical Society. 114: 2112-2121. DOI: 10.1021/Ja00032A027  1
1991 Kim YJ, Bernstein MP, Roth ASG, Romesberg FE, Williard PG, Fuller DJ, Harrison AT, Collum DB. On the structure and reactivity of lithium diisopropylamide (LDA) in hydrocarbon solutions. Formation of unsolvated ketone, ester, and carboxamide enolates Journal of Organic Chemistry. 56: 4435-4439. DOI: 10.1021/Jo00014A019  1
1991 Romesberg FE, Gilchrist JH, Harrison AT, Fuller DJ, Collum DB. On the structure of lithium 2,2,6,6-tetramethylpiperidide (LiTMP) and lithium diisopropylamide (LDA) in the presence of hexamethylphosphoramide (HMPA): Structure-dependent distribution of cyclic and open dimers, ion triplets, and monomers Journal of the American Chemical Society. 113: 5751-5757.  1
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