Victor John Cee - Publications

Affiliations: 
2003 Harvard University, Cambridge, MA, United States 

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Shin Y, Jeong JW, Wurz RP, Achanta P, Arvedson T, Bartberger MD, Campuzano IDG, Fucini R, Hansen SK, Ingersoll J, Iwig JS, Lipford JR, Ma V, Kopecky DJ, McCarter J, ... ... Cee VJ, et al. Discovery of -(1-Acryloylazetidin-3-yl)-2-(1-indol-1-yl)acetamides as Covalent Inhibitors of KRAS. Acs Medicinal Chemistry Letters. 10: 1302-1308. PMID 31531201 DOI: 10.1021/acsmedchemlett.9b00258  0.56
2019 Wang HL, Andrews K, Booker SK, Canon J, Cee VJ, Chavez F, Chen Y, Eastwood H, Guerrero N, Herberich B, Hickman D, Lanman BA, Laszlo Iii J, Lee MR, Lipford JR, et al. Discovery of (R)-8-(6-Methyl-4-oxo-1,4,5,6-tetrahydropyrrolo[3,4-b]pyrrol-2-yl)-3-(1-methylcyclopropyl)-2-((1-methylcyclopropyl)amino)quinazolin-4(3H)-one, a Potent and Selective Pim- 1/2 Kinase Inhibitor for Hematological Malignancies. Journal of Medicinal Chemistry. PMID 30624936 DOI: 10.1021/acs.jmedchem.8b01733  0.56
2018 Wurz RP, Cee VJ. Targeted Degradation of MDM2 as a New Approach to Improve the Efficacy of MDM2-p53 Inhibitors. Journal of Medicinal Chemistry. PMID 30575392 DOI: 10.1021/acs.jmedchem.8b01945  0.56
2017 Wurz RP, Dellamaggiore K, Dou H, Javier N, Lo MC, McCarter JD, Mohl D, Sastri C, Lipford JR, Cee VJ. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. Journal of Medicinal Chemistry. PMID 28378579 DOI: 10.1021/acs.jmedchem.6b01781  0.56
2016 Pettus LH, Andrews KL, Booker SK, Chen J, Cee VJ, Chavez F, Chen Y, Eastwood H, Guerrero N, Herberich BJ, Hickman D, Lanman BA, Laszlo Iii J, Lee MR, Lipford JR, et al. Discovery and Optimization of Quinazolinone-pyrrolopyrrolones as Potent and Orally Bioavailable pan-Pim Kinase Inhibitors. Journal of Medicinal Chemistry. PMID 27285051 DOI: 10.1021/acs.jmedchem.6b00610  0.72
2016 Cee VJ, Chavez F, Herberich B, Lanman BA, Pettus LH, Reed AB, Wu B, Wurz RP, Andrews KL, Chen J, Hickman D, Laszlo J, Lee MR, Guerrero N, Mattson BK, et al. Discovery and Optimization of Macrocyclic Quinoxaline-pyrrolo-dihydropiperidinones as Potent Pim-1/2 Kinase Inhibitors. Acs Medicinal Chemistry Letters. 7: 408-12. PMID 27096050 DOI: 10.1021/acsmedchemlett.5b00403  0.72
2015 Campuzano ID, San Miguel T, Rowe T, Onea D, Cee VJ, Arvedson T, McCarter JD. High-Throughput Mass Spectrometric Analysis of Covalent Protein-Inhibitor Adducts for the Discovery of Irreversible Inhibitors: A Complete Workflow. Journal of Biomolecular Screening. PMID 26676098 DOI: 10.1177/1087057115621288  0.72
2015 Cee VJ, Volak LP, Chen Y, Bartberger MD, Tegley C, Arvedson T, McCarter J, Tasker AS, Fotsch C. Systematic Study of the Glutathione (GSH) Reactivity of N-Arylacrylamides: 1. Effects of Aryl Substitution. Journal of Medicinal Chemistry. PMID 26580091 DOI: 10.1021/acs.jmedchem.5b01018  0.72
2015 Geuns-Meyer S, Cee VJ, Deak HL, Du B, Hodous BL, Nguyen HN, Olivieri PR, Schenkel LB, Vaida KR, Andrews P, Bak A, Be X, Beltran PJ, Bush TL, Chaves MK, et al. Discovery of N-(4-(3-(2-Aminopyrimidin-4-yl)pyridin-2-yloxy)phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine (AMG 900), A Highly Selective, Orally Bioavailable Inhibitor of Aurora Kinases with Activity against Multidrug-Resistant Cancer Cell Lines. Journal of Medicinal Chemistry. PMID 25970324 DOI: 10.1021/acs.jmedchem.5b00183  0.72
2015 Wu B, Wang HL, Cee VJ, Lanman BA, Nixey T, Pettus L, Reed AB, Wurz RP, Guerrero N, Sastri C, Winston J, Lipford JR, Lee MR, Mohr C, Andrews KL, et al. Discovery of 5-(1H-indol-5-yl)-1,3,4-thiadiazol-2-amines as potent PIM inhibitors. Bioorganic & Medicinal Chemistry Letters. 25: 775-80. PMID 25616902 DOI: 10.1016/j.bmcl.2014.12.091  0.72
2015 Wurz RP, Pettus LH, Jackson C, Wu B, Wang HL, Herberich B, Cee V, Lanman BA, Reed AB, Chavez F, Nixey T, Laszlo J, Wang P, Nguyen Y, Sastri C, et al. The discovery and optimization of aminooxadiazoles as potent Pim kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 25: 847-55. PMID 25599837 DOI: 10.1016/j.bmcl.2014.12.067  0.72
2015 Wang HL, Cee VJ, Chavez F, Lanman BA, Reed AB, Wu B, Guerrero N, Lipford JR, Sastri C, Winston J, Andrews KL, Huang X, Lee MR, Mohr C, Xu Y, et al. The discovery of novel 3-(pyrazin-2-yl)-1H-indazoles as potent pan-Pim kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 25: 834-40. PMID 25597005 DOI: 10.1016/j.bmcl.2014.12.068  0.72
2014 Lanman BA, Reed AB, Cee VJ, Hong FT, Pettus LH, Wurz RP, Andrews KL, Jiang J, McCarter JD, Mullady EL, San Miguel T, Subramanian R, Wang L, Whittington DA, Wu T, et al. Phosphoinositide-3-kinase inhibitors: evaluation of substituted alcohols as replacements for the piperazine sulfonamide portion of AMG 511. Bioorganic & Medicinal Chemistry Letters. 24: 5630-4. PMID 25466188 DOI: 10.1016/j.bmcl.2014.10.085  0.72
2013 Xu H, McElvain M, Fiorino M, Henkle B, Sherman L, Xu Y, Tominey E, Kelley K, Adlam M, Bürli R, Siu J, Wong M, Cee VJ. Predictability of peripheral lymphocyte reduction of novel S1P1 agonists by in vitro GPCR signaling profile. Journal of Biomolecular Screening. 18: 997-1007. PMID 23686102 DOI: 10.1177/1087057113488629  0.72
2012 Harrington PE, Croghan MD, Fotsch C, Frohn M, Lanman BA, Pennington LD, Pickrell AJ, Reed AB, Sham KK, Tasker A, Arnett HA, Fiorino M, Lee MR, McElvain M, Morrison HG, ... ... Cee VJ, et al. Optimization of a Potent, Orally Active S1P1 Agonist Containing a Quinolinone Core. Acs Medicinal Chemistry Letters. 3: 74-8. PMID 24900374 DOI: 10.1021/ml200252b  0.72
2012 Norman MH, Andrews KL, Bo YY, Booker SK, Caenepeel S, Cee VJ, D'Angelo ND, Freeman DJ, Herberich BJ, Hong FT, Jackson CL, Jiang J, Lanman BA, Liu L, McCarter JD, et al. Selective class I phosphoinositide 3-kinase inhibitors: optimization of a series of pyridyltriazines leading to the identification of a clinical candidate, AMG 511. Journal of Medicinal Chemistry. 55: 7796-816. PMID 22897589 DOI: 10.1021/jm300846z  0.72
2012 Smith AL, D'Angelo ND, Bo YY, Booker SK, Cee VJ, Herberich B, Hong FT, Jackson CL, Lanman BA, Liu L, Nishimura N, Pettus LH, Reed AB, Tadesse S, Tamayo NA, et al. Structure-based design of a novel series of potent, selective inhibitors of the class I phosphatidylinositol 3-kinases. Journal of Medicinal Chemistry. 55: 5188-219. PMID 22548365 DOI: 10.1021/jm300184s  0.72
2012 Nguyen HN, Cee VJ, Deak HL, Du B, Faber KP, Gunaydin H, Hodous BL, Hollis SL, Krolikowski PH, Olivieri PR, Patel VF, Romero K, Schenkel LB, Geuns-Meyer SD. Synthesis of 4-substituted chlorophthalazines, dihydrobenzoazepinediones, 2-pyrazolylbenzoic acid, and 2-pyrazolylbenzohydrazide via 3-substituted 3-hydroxyisoindolin-1-ones. The Journal of Organic Chemistry. 77: 3887-906. PMID 22458369 DOI: 10.1021/jo3000628  0.72
2012 Reed AB, Lanman BA, Neira S, Harrington PE, Sham KK, Frohn M, Pickrell AJ, Tasker AS, Gore A, Fiorino M, Itano A, McElvain M, Middleton S, Morrison H, Xu H, ... ... Cee VJ, et al. Isoform-selective thiazolo[5,4-b]pyridine S1P1 agonists possessing acyclic amino carboxylate head-groups. Bioorganic & Medicinal Chemistry Letters. 22: 1779-83. PMID 22257889 DOI: 10.1016/j.bmcl.2011.12.073  0.72
2012 Pennington LD, Croghan MD, Sham KK, Pickrell AJ, Harrington PE, Frohn MJ, Lanman BA, Reed AB, Lee MR, Xu H, McElvain M, Xu Y, Zhang X, Fiorino M, Horner M, ... ... Cee VJ, et al. Quinolinone-based agonists of S1P₁: use of a N-scan SAR strategy to optimize in vitro and in vivo activity. Bioorganic & Medicinal Chemistry Letters. 22: 527-31. PMID 22104144 DOI: 10.1016/j.bmcl.2011.10.085  0.72
2012 Frohn M, Cee VJ, Lanman BA, Pickrell AJ, Golden J, Rivenzon-Segal D, Middleton S, Fiorino M, Xu H, Schrag M, Xu Y, McElvain M, Muller K, Siu J, Bürli R. Novel 5- and 6-subtituted benzothiazoles with improved physicochemical properties: potent S1P₁ agonists with in vivo lymphocyte-depleting activity. Bioorganic & Medicinal Chemistry Letters. 22: 628-33. PMID 22100314 DOI: 10.1016/j.bmcl.2011.10.069  0.72
2011 Cee VJ, Frohn M, Lanman BA, Golden J, Muller K, Neira S, Pickrell A, Arnett H, Buys J, Gore A, Fiorino M, Horner M, Itano A, Lee MR, McElvain M, et al. Discovery of AMG 369, a Thiazolo[5,4-b]pyridine Agonist of S1P1 and S1P5. Acs Medicinal Chemistry Letters. 2: 107-12. PMID 24900288 DOI: 10.1021/ml100306h  0.72
2011 Lanman BA, Cee VJ, Cheruku SR, Frohn M, Golden J, Lin J, Lobera M, Marantz Y, Muller KM, Neira SC, Pickrell AJ, Rivenzon-Segal D, Schutz N, Sharadendu A, Yu X, et al. Discovery of a Potent, S1P3-Sparing Benzothiazole Agonist of Sphingosine-1-Phosphate Receptor 1 (S1P1). Acs Medicinal Chemistry Letters. 2: 102-6. PMID 24900287 DOI: 10.1021/ml100228m  0.72
2011 Pennington LD, Sham KK, Pickrell AJ, Harrington PE, Frohn MJ, Lanman BA, Reed AB, Croghan MD, Lee MR, Xu H, McElvain M, Xu Y, Zhang X, Fiorino M, Horner M, ... ... Cee VJ, et al. 4-Methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide: A Potent and Selective Agonist of S1P1. Acs Medicinal Chemistry Letters. 2: 752-7. PMID 24900263 DOI: 10.1021/ml2001399  0.72
2010 Payton M, Bush TL, Chung G, Ziegler B, Eden P, McElroy P, Ross S, Cee VJ, Deak HL, Hodous BL, Nguyen HN, Olivieri PR, Romero K, Schenkel LB, Bak A, et al. Preclinical evaluation of AMG 900, a novel potent and highly selective pan-aurora kinase inhibitor with activity in taxane-resistant tumor cell lines. Cancer Research. 70: 9846-54. PMID 20935223 DOI: 10.1158/0008-5472.CAN-10-3001  0.72
2010 Cee VJ, Schenkel LB, Hodous BL, Deak HL, Nguyen HN, Olivieri PR, Romero K, Bak A, Be X, Bellon S, Bush TL, Cheng AC, Chung G, Coats S, Eden PM, et al. Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor. Journal of Medicinal Chemistry. 53: 6368-77. PMID 20684549 DOI: 10.1021/jm100394y  0.72
2010 Cee VJ. Aliskiren (Tekturna), The First-in-Class Renin Inhibitor for Hypertension Modern Drug Synthesis. 141-158. DOI: 10.1002/9780470768594.ch11  0.72
2009 Cee VJ, Chen DY, Lee MR, Nicolaou KC. Cortistatin A is a high-affinity ligand of protein kinases ROCK, CDK8, and CDK11. Angewandte Chemie (International Ed. in English). 48: 8952-7. PMID 19844931 DOI: 10.1002/anie.200904778  0.72
2009 Cee VJ, Cheng AC, Romero K, Bellon S, Mohr C, Whittington DA, Bak A, Bready J, Caenepeel S, Coxon A, Deak HL, Fretland J, Gu Y, Hodous BL, Huang X, et al. Pyridyl-pyrimidine benzimidazole derivatives as potent, selective, and orally bioavailable inhibitors of Tie-2 kinase. Bioorganic & Medicinal Chemistry Letters. 19: 424-7. PMID 19062275 DOI: 10.1016/j.bmcl.2008.11.056  0.72
2008 Keck GE, Giles RL, Cee VJ, Wager CA, Yu T, Kraft MB. Total synthesis of epothilones B and D: stannane equivalents for beta-keto ester dianions. The Journal of Organic Chemistry. 73: 9675-91. PMID 18991385 DOI: 10.1021/jo802215v  0.72
2007 Hodous BL, Geuns-Meyer SD, Hughes PE, Albrecht BK, Bellon S, Caenepeel S, Cee VJ, Chaffee SC, Emery M, Fretland J, Gallant P, Gu Y, Johnson RE, Kim JL, Long AM, et al. Synthesis, structural analysis, and SAR studies of triazine derivatives as potent, selective Tie-2 inhibitors. Bioorganic & Medicinal Chemistry Letters. 17: 2886-9. PMID 17350837 DOI: 10.1016/j.bmcl.2007.02.067  0.72
2007 Cee VJ, Albrecht BK, Geuns-Meyer S, Hughes P, Bellon S, Bready J, Caenepeel S, Chaffee SC, Coxon A, Emery M, Fretland J, Gallant P, Gu Y, Hodous BL, Hoffman D, et al. Alkynylpyrimidine amide derivatives as potent, selective, and orally active inhibitors of Tie-2 kinase. Journal of Medicinal Chemistry. 50: 627-40. PMID 17253679 DOI: 10.1021/jm061112p  0.72
2007 Hodous BL, Geuns-Meyer SD, Hughes PE, Albrecht BK, Bellon S, Bready J, Caenepeel S, Cee VJ, Chaffee SC, Coxon A, Emery M, Fretland J, Gallant P, Gu Y, Hoffman D, et al. Evolution of a highly selective and potent 2-(pyridin-2-yl)-1,3,5-triazine Tie-2 kinase inhibitor. Journal of Medicinal Chemistry. 50: 611-26. PMID 17253678 DOI: 10.1021/jm061107l  0.72
2006 DiMauro EF, Newcomb J, Nunes JJ, Bemis JE, Boucher C, Buchanan JL, Buckner WH, Cee VJ, Chai L, Deak HL, Epstein LF, Faust T, Gallant P, Geuns-Meyer SD, Gore A, et al. Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity. Journal of Medicinal Chemistry. 49: 5671-86. PMID 16970394 DOI: 10.1021/jm0605482  0.72
2006 Evans DA, Cee VJ, Siska SJ. Asymmetric induction in methyl ketone aldol additions to alpha-alkoxy and alpha,beta-bisalkoxy aldehydes: a model for acyclic stereocontrol. Journal of the American Chemical Society. 128: 9433-41. PMID 16848480 DOI: 10.1021/ja061010o  0.72
2006 Cee VJ, Cramer CJ, Evans DA. Theoretical investigation of enolborane addition to alpha-heteroatom-substituted aldehydes. Relevance of the Cornforth and polar Felkin-Anh models for asymmetric induction. Journal of the American Chemical Society. 128: 2920-30. PMID 16506771 DOI: 10.1021/ja0555670  0.72
2006 Cee VJ, Downing NS. A one-pot method for the synthesis of 2-aminobenzimidazoles and related heterocycles Tetrahedron Letters. 47: 3747-3750. DOI: 10.1016/j.tetlet.2006.03.112  0.72
2006 Cee VJ, Olhava EJ. Leading ACE Inhibitors for Hypertension The Art of Drug Synthesis. 143-158. DOI: 10.1002/9780470134979.ch10  0.72
2003 Evans DA, Siska SJ, Cee VJ. Resurrecting the Cornforth model for carbonyl addition: studies on the origin of 1,2-asymmetric induction in enolate additions to heteroatom-substituted aldehydes. Angewandte Chemie (International Ed. in English). 42: 1761-5. PMID 12707900 DOI: 10.1002/anie.200350979  0.72
2002 Kroll JH, Donahue NM, Cee VJ, Demerjian KL, Anderson JG. Gas-phase ozonolysis of alkenes: formation of OH from anti carbonyl oxides. Journal of the American Chemical Society. 124: 8518-9. PMID 12121079 DOI: 10.1021/ja0266060  0.72
2001 Keck GE, Wager CA, Wager TT, Savin KA, Covel JA, McLaws MD, Krishnamurthy D, Cee VJ. Asymmetric Total Synthesis of Rhizoxin D Financial support has been provided by the National Institutes of Health (through grant GM-28961) and by Pfizer, Inc. Angewandte Chemie (International Ed. in English). 40: 231-234. PMID 11169722 DOI: 10.1002/1521-3773(20010105)40:1<231::AID-ANIE231>3.0.CO;2-W  0.72
2000 Evans DA, Cee VJ, Smith TE, Fitch DM, Cho PS. Asymmetric Synthesis of Phorboxazole B-Part I: Synthesis of the C(20)-C(38) and C(39)-C(46) Subunits Financial support was provided by the National Institutes of Health (GM-33328) and the National Science Foundation. An American Cancer Society Postdoctoral Fellowship to T.E.S. and an NSF Predoctoral Fellowship to V.J.C. are gratefully acknowledged. The NIH BRS Shared Instrumentation Grant Program 1-S10-RR04870 and the NSF (CHE 88-14019) are acknowledged for providing NMR facilities. Angewandte Chemie (International Ed. in English). 39: 2533-2536. PMID 10941127 DOI: 10.1002/1521-3773(20000717)39:14<2533::AID-ANIE2533>3.0.CO;2-B  0.72
2000 Evans DA, Fitch DM, Smith TE, Cee VJ. Application of complex aldol reactions to the total synthesis of phorboxazole B Journal of the American Chemical Society. 122: 10033-10046. DOI: 10.1021/ja002356g  0.72
1999 Evans DA, Cee VJ, Smith TE, Santiago KJ. Selective lithiation of 2-methyloxazoles. Applications to pivotal bond constructions in the phorboxazole nucleus. Organic Letters. 1: 87-90. PMID 10822540  0.72
1999 Patrick DL, Cee VJ, Morse MD, Beebe TP. Nanometer-Scale Aspects of Molecular Ordering in Nanocrystalline Domains at a Solid Interface: The Role of Liquid Crystal-Surface Interactions Studied by STM and Molecule Corrals Journal of Physical Chemistry B. 103: 8328-8336.  0.72
1998 Stevens F, Patrick DL, Cee VJ, Purcell TJ, Beebe TP. Transition from epitaxial to nonepitaxial ordered monolayers in pyrolyzed 8CB studied by STM Langmuir. 14: 2396-2401.  0.72
1996 Patrick DL, Cee VJ, Beebe TP. Mechanism of molecular ordering in monolayer liquid crystal films Journal of Physical Chemistry. 100: 8478-8481.  0.72
1996 Patrick DL, Cee VJ, Purcell TJ, Beebe TP. Defect pinning in monolayer films by highly controlled graphite defects: Molecule corrals Langmuir. 12: 1830-1835.  0.72
1995 Cee VJ, Patrick DL, Beebe TP. Unusual aspects of superperiodic features on highly oriented pyrolytic graphite Surface Science. 329: 141-148. DOI: 10.1016/0039-6028(95)00013-5  0.72
1994 Patrick DL, Cee VJ, Beebe TP. "Molecule corrals" for studies of monolayer organic films. Science (New York, N.Y.). 265: 231-4. PMID 17750666 DOI: 10.1126/science.265.5169.231  0.72
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