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Chiles Wade Downey - Publications

Affiliations: 
2004 Harvard University, Cambridge, MA, United States 
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Downey CW, Robertson GAL, Santa J, Flicker KR, Stith WM. One-pot silyl ketene imine formation-nucleophilic addition reactions of acetonitrile with acetals and nitrones Tetrahedron Letters. 61: 151537. DOI: 10.1016/j.tetlet.2019.151537  0.755
2019 Downey CW, Dixon GJ, Ingersoll JA, Fuller CN, MacCormac KW, Takashima A, Sediqui R. One-pot enol silane formation-Mukaiyama aldol reactions: Crossed aldehyde-aldehyde coupling, thioester substrates, and reactions in ester solvents Tetrahedron Letters. 60: 151192. DOI: 10.1016/j.tetlet.2019.151192  0.732
2018 Downey CW, Confair DN, Liu Y, Heafner ED. One-Pot Enol Silane Formation-Alkylation of Ketones with Propargyl Carboxylates Promoted by Trimethylsilyl Trifluoromethanesulfonate. The Journal of Organic Chemistry. PMID 30248260 DOI: 10.1021/acs.joc.8b01997  0.738
2018 Downey CW, Glist HM, Takashima A, Bottum SR, Dixon GJ. Chalcone and cinnamate synthesis via one-pot enol silane formation-Mukaiyama aldol reactions of ketones and acetate esters Tetrahedron Letters. 59: 3080-3083. DOI: 10.1016/j.tetlet.2018.06.066  0.774
2018 Downey CW, Johnson MW. Corrigendum to “A tandem enol silane Formation-Mukaiyama aldol reaction mediated by TMSOTf” [Tetrahedron Lett. 48 (2007) 3559–3562] Tetrahedron Letters. 59: 1268. DOI: 10.1016/J.Tetlet.2018.01.088  0.715
2017 Downey CW, Lee AY, Goodin JR, Botelho CJ, Stith WM. Mukaiyama addition of (trimethylsilyl)acetonitrile to dimethyl acetals mediated by trimethylsilyl trifluoromethanesulfonate Tetrahedron Letters. 58: 3496-3499. DOI: 10.1016/j.tetlet.2017.07.082  0.625
2016 Downey CW, Ingersoll JA, Glist HM, Dombrowski CM, Barnett AT. ChemInform Abstract: One-Pot Silyl Ketene Acetal-Formation Mukaiyama-Mannich Additions to Imines Mediated by Trimethylsilyl Trifluoromethanesulfonate. Cheminform. 47: no-no. DOI: 10.1002/chin.201615079  0.681
2015 Downey CW, Poff CD, Nizinski AN. Friedel-Crafts Hydroxyalkylation of Indoles Mediated by Trimethylsilyl Trifluoromethanesulfonate. The Journal of Organic Chemistry. 80: 10364-9. PMID 26393376 DOI: 10.1021/acs.joc.5b01681  0.686
2014 Downey CW, Covington SE, Obenschain DC, Halliday E, Rague JT, Confair DN. Silyl trifluoromethanesulfonate-activated para-methoxybenzyl methyl ether as an alkylating agent for thiols and aryl ketones Tetrahedron Letters. 55: 5213-5215. DOI: 10.1016/j.tetlet.2014.07.068  0.589
2014 Downey CW, Maxwell EN, Confair DN. Silyl triflate-accelerated additions of catalytically generated zinc acetylides to N-phenyl nitrones Tetrahedron Letters. 4959-4961. DOI: 10.1016/j.tetlet.2014.07.015  0.603
2013 Downey CW, Dombrowski CM, Maxwell EN, Safran CL, Akomah OA. One-pot enol silane formation/mukaiyama-mannich addition of ketones, amides, and thioesters to nitrones in the presence of trialkylsilyl trifluoromethanesulfonates European Journal of Organic Chemistry. 5716-5720. DOI: 10.1002/ejoc.201300691  0.697
2013 Downey CW, Craciun S, Neferu AM, Vivelo CA, Mueller CJ, Southall BC, Corsi S, Etchill EW, Sault R. ChemInform Abstract: One-Pot Synthesis of (Z)-β-Sulfonyl Enoates from Ethyl Propiolate. Cheminform. 44: no-no. DOI: 10.1002/chin.201304053  0.563
2013 Downey CW, Craciun S, Vivelo CA, Neferu AM, Mueller CJ, Corsi S. ChemInform Abstract: One-Pot Three-Step Thioconjugate Addition-Oxidation-Diels-Alder Reactions of Ethyl Propiolate. Cheminform. 44: no-no. DOI: 10.1002/chin.201303073  0.693
2012 Downey CW, Craciun S, Vivelo CA, Neferu AM, Mueller CJ, Corsi S. One-pot three-step thioconjugate addition-oxidation-Diels-Alder reactions of ethyl propiolate Tetrahedron Letters. 53: 5766-5768. DOI: 10.1016/j.tetlet.2012.08.054  0.682
2012 Downey CW, Craciun S, Neferu AM, Vivelo CA, Mueller CJ, Southall BC, Corsi S, Etchill EW, Sault RJ. One-pot synthesis of (Z)-β-sulfonyl enoates from ethyl propiolate Tetrahedron Letters. 53: 5763-5765. DOI: 10.1016/j.tetlet.2012.08.051  0.549
2011 Downey CW, Fleisher AS, Rague JT, Safran CL, Venable ME, Pike RD. Synthesis of N-acyl-N,O-acetals from N-aryl amides and acetals in the presence of TMSOTf Tetrahedron Letters. 52: 4756-4759. DOI: 10.1016/J.Tetlet.2011.07.023  0.686
2010 Downey CW, Johnson MW, Lawrence DH, Fleisher AS, Tracy KJ. Acetic acid aldol reactions in the presence of trimethylsilyl trifluoromethanesulfonate. The Journal of Organic Chemistry. 75: 5351-4. PMID 20590083 DOI: 10.1021/Jo100828C  0.691
2010 Evans DA, Tedrow JS, Shaw JT, Downey CW. ChemInform Abstract: Diastereoselective Magnesium Halide-Catalyzed anti-Aldol Reactions of Chiral N-Acyloxazolidinones. Cheminform. 33: no-no. DOI: 10.1002/chin.200226034  0.828
2010 Evans DA, Scheidt KA, Downey CW. ChemInform Abstract: Synthesis of (-)-Epibatidine Cheminform. 33: no-no. DOI: 10.1002/chin.200204220  0.719
2009 Downey CW, Mahoney BD, Lipari VR. Trimethylsilyl trifluoromethanesulfonate-accelerated addition of catalytically generated zinc acetylides to aldehydes. The Journal of Organic Chemistry. 74: 2904-6. PMID 19260695 DOI: 10.1021/jo900102w  0.702
2008 Downey CW, Johnson MW, Tracy KJ. One-pot enol silane formation-Mukaiyama aldol-type addition to dimethyl acetals mediated by TMSOTf. The Journal of Organic Chemistry. 73: 3299-302. PMID 18335962 DOI: 10.1021/Jo8001084  0.777
2007 Downey CW, Johnson MW. A tandem enol silane formation-Mukaiyama aldol reaction mediated by TMSOTf Tetrahedron Letters. 48: 3559-3562. DOI: 10.1016/J.Tetlet.2007.03.088  0.766
2005 Suárez A, Downey CW, Fu GC. Kinetic resolutions of azomethine imines via copper-catalyzed [3 + 2] cycloadditions. Journal of the American Chemical Society. 127: 11244-5. PMID 16089444 DOI: 10.1021/Ja052876H  0.734
2004 Smith TE, Djang M, Velander AJ, Downey CW, Carroll KA, Van Alphen S. Versatile asymmetric synthesis of the kavalactones: first synthesis of (+)-kavain. Organic Letters. 6: 2317-20. PMID 15228268 DOI: 10.1021/ol0493960  0.797
2003 Evans DA, Seidel D, Rueping M, Lam HW, Shaw JT, Downey CW. A new copper acetate-bis(oxazoline)-catalyzed, enantioselective Henry reaction. Journal of the American Chemical Society. 125: 12692-3. PMID 14558801 DOI: 10.1021/Ja0373871  0.815
2003 Evans DA, Downey CW, Hubbs JL. Ni(II) bis(oxazoline)-catalyzed enantioselective syn aldol reactions of N-propionylthiazolidinethiones in the presence of silyl triflates. Journal of the American Chemical Society. 125: 8706-7. PMID 12862448 DOI: 10.1021/Ja035509J  0.78
2003 Kosmrlj J, Weigel LO, Evans DA, Downey CW, Wu J. Unfunctionalized, alpha-epimerizable nonracemic ketones and aldehydes can be accessed by crystallization-induced dynamic resolution of imines. Journal of the American Chemical Society. 125: 3208-9. PMID 12630864 DOI: 10.1021/Ja029715N  0.74
2002 Evans DA, Downey CW, Shaw JT, Tedrow JS. Magnesium halide-catalyzed anti-aldol reactions of chiral N-acylthiazolidinethiones. Organic Letters. 4: 1127-30. PMID 11922799 DOI: 10.1021/Ol025553O  0.835
2002 Evans DA, Tedrow JS, Shaw JT, Downey CW. Diastereoselective magnesium halide-catalyzed anti-aldol reactions of chiral N-acyloxazolidinones. Journal of the American Chemical Society. 124: 392-3. PMID 11792206 DOI: 10.1021/Ja0119548  0.828
2001 Evans DA, Scheidt KA, Downey CW. Synthesis of (-)-epibatidine. Organic Letters. 3: 3009-12. PMID 11554830 DOI: 10.1021/Ol016420Q  0.801
2001 Evans DA, Rovis T, Kozlowski MC, Downey CW, Tedrow JS. ChemInform Abstract: Enantioselective Lewis Acid Catalyzed Michael Reactions of Alkylidene Malonates. Catalysis by C2-Symmetric Bis(oxazoline) Copper(II) Complexes in the Synthesis of Chiral, Differentiated Glutarate Esters. Cheminform. 32: no-no. DOI: 10.1002/chin.200103030  0.823
2000 Evans DA, Rovis T, Kozlowski MC, Downey CW, Tedrow JS. Enantioselective Lewis acid catalyzed Michael reactions of alkylidene malonates. Catalysis by C2-symmetric bis(oxazoline) copper(II) complexes in the synthesis of chiral, differentiated glutarate esters Journal of the American Chemical Society. 122: 9134-9142. DOI: 10.1021/Ja002246+  0.811
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