Yingcai Wang - Publications

Affiliations: 
2002 Texas A & M University, College Station, TX, United States 

23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Yu M, Wang Y, Zhu J, Bartberger MD, Canon J, Chen A, Chow D, Eksterowicz J, Fox B, Fu J, Gribble M, Huang X, Li Z, Liu JJ, Lo MC, et al. Discovery of Potent and Simplified Piperidinone-Based Inhibitors of the MDM2-p53 Interaction. Acs Medicinal Chemistry Letters. 5: 894-9. PMID 25147610 DOI: 10.1021/ml500142b  0.96
2014 Wang Y, Zhu J, Liu JJ, Chen X, Mihalic J, Deignan J, Yu M, Sun D, Kayser F, McGee LR, Lo MC, Chen A, Zhou J, Ye Q, Huang X, et al. Optimization beyond AMG 232: discovery and SAR of sulfonamides on a piperidinone scaffold as potent inhibitors of the MDM2-p53 protein-protein interaction. Bioorganic & Medicinal Chemistry Letters. 24: 3782-5. PMID 25042256 DOI: 10.1016/j.bmcl.2014.06.073  0.96
2014 Liu JJ, Wang Y, Ma Z, Schmitt M, Zhu L, Brown SP, Dransfield PJ, Sun Y, Sharma R, Guo Q, Zhuang R, Zhang J, Luo J, Tonn GR, Wong S, et al. Optimization of GPR40 Agonists for Type 2 Diabetes. Acs Medicinal Chemistry Letters. 5: 517-21. PMID 24900872 DOI: 10.1021/ml400501x  0.96
2014 Du X, Dransfield PJ, Lin DC, Wong S, Wang Y, Wang Z, Kohn T, Yu M, Brown SP, Vimolratana M, Zhu L, Li AR, Su Y, Jiao X, Liu JJ, et al. Improving the Pharmacokinetics of GPR40/FFA1 Full Agonists. Acs Medicinal Chemistry Letters. 5: 384-9. PMID 24900845 DOI: 10.1021/ml4005123  0.96
2014 Wang Y, Connors R, Fan P, Wang X, Wang Z, Liu J, Kayser F, Medina JC, Johnstone S, Xu H, Thibault S, Walker N, Conn M, Zhang Y, Liu Q, et al. Structure-assisted discovery of the first non-retinoid ligands for Retinol-Binding Protein 4. Bioorganic & Medicinal Chemistry Letters. 24: 2885-91. PMID 24835984 DOI: 10.1016/j.bmcl.2014.04.089  0.96
2014 Wang Y, Yu M, Zhu J, Zhang JK, Kayser F, Medina JC, Siegler K, Conn M, Shan B, Grillo MP, Liu JJ, Coward P. Discovery and optimization of 5-(2-((1-(phenylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl)oxy)pyridin-4-yl)-1,2,4-oxadiazoles as novel gpr119 agonists. Bioorganic & Medicinal Chemistry Letters. 24: 1133-7. PMID 24440299 DOI: 10.1016/j.bmcl.2013.12.127  0.96
2014 Yu M, Ken Zhang J, Wang Y, Zhu J, Kayser F, Medina JC, Siegler K, Conn M, Shan B, Grillo MP, Coward P, Jim Liu J. Discovery and optimization of N-(3-(1,3-dioxo-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-4-yloxy)phenyl)benzenesulfonamides as novel GPR119 agonists. Bioorganic & Medicinal Chemistry Letters. 24: 156-60. PMID 24332491 DOI: 10.1016/j.bmcl.2013.11.053  0.96
2013 Wang Y, Liu JJ, Dransfield PJ, Zhu L, Wang Z, Du X, Jiao X, Su Y, Li AR, Brown SP, Kasparian A, Vimolratana M, Yu M, Pattaropong V, Houze JB, et al. Discovery and Optimization of Potent GPR40 Full Agonists Containing Tricyclic Spirocycles. Acs Medicinal Chemistry Letters. 4: 551-5. PMID 24900707 DOI: 10.1021/ml300427u  0.96
2013 Xiong Y, Swaminath G, Cao Q, Yang L, Guo Q, Salomonis H, Lu J, Houze JB, Dransfield PJ, Wang Y, Liu JJ, Wong S, Schwandner R, Steger F, Baribault H, et al. Activation of FFA1 mediates GLP-1 secretion in mice. Evidence for allosterism at FFA1. Molecular and Cellular Endocrinology. 369: 119-29. PMID 23403053 DOI: 10.1016/j.mce.2013.01.009  0.96
2013 Luo J, Nguyen K, Chen M, Tran T, Hao J, Tian B, Rulifson IC, Zhang Y, Tian L, Zhang Y, Lopez E, Lin DC, Wang Y, Ma Z, Houze J, et al. Evaluating insulin secretagogues in a humanized mouse model with functional human islets. Metabolism: Clinical and Experimental. 62: 90-9. PMID 22982177 DOI: 10.1016/j.metabol.2012.07.010  0.96
2012 Lin DC, Guo Q, Luo J, Zhang J, Nguyen K, Chen M, Tran T, Dransfield PJ, Brown SP, Houze J, Vimolratana M, Jiao XY, Wang Y, Birdsall NJ, Swaminath G. Identification and pharmacological characterization of multiple allosteric binding sites on the free fatty acid 1 receptor. Molecular Pharmacology. 82: 843-59. PMID 22859723 DOI: 10.1124/mol.112.079640  0.96
2012 Liu JJ, Wang Y, Johnson MG, Li AR, Shen W, Wang X, Su Y, Brown M, Van Lengerich B, Rickel E, Martin T, Budelsky A, Seitz L, Danao J, Tang HL, et al. Optimization of phenylacetic acid derivatives for balanced CRTH2 and DP dual antagonists. Bioorganic & Medicinal Chemistry Letters. 22: 1686-9. PMID 22264478 DOI: 10.1016/j.bmcl.2011.12.107  0.96
2012 Wang Y, Fu Z, Schmitt M, Wang X, Shen W, Rickel E, Martin T, Budelsky A, Marshall D, Collins T, Tang HL, Medina JC, Liu JJ. Optimization of phenylacetic acid derivatives for CRTH2 and DP selective antagonism. Bioorganic & Medicinal Chemistry Letters. 22: 367-70. PMID 22119474 DOI: 10.1016/j.bmcl.2011.10.123  0.96
2011 Liu J, Li AR, Wang Y, Johnson MG, Su Y, Shen W, Wang X, Lively S, Brown M, Lai S, Gonzalez Lopez De Turiso F, Xu Q, Van Lengerich B, Schmitt M, Fu Z, et al. Discovery of AMG 853, a CRTH2 and DP Dual Antagonist. Acs Medicinal Chemistry Letters. 2: 326-30. PMID 24900313 DOI: 10.1021/ml1002234  0.96
2011 Swaminath G, Jaeckel P, Guo Q, Cardozo M, Weiszmann J, Lindberg R, Wang Y, Schwandner R, Li Y. Mutational analysis of G-protein coupled receptor--FFA2. Biochemical and Biophysical Research Communications. 405: 122-7. PMID 21216233 DOI: 10.1016/j.bbrc.2010.12.139  0.96
2010 Swaminath G, Jaeckel P, Guo Q, Cardozo M, Weiszmann J, Lindberg R, Wang Y, Schwandner R, Li Y. Allosteric rescuing of loss-of-function FFAR2 mutations. Febs Letters. 584: 4208-14. PMID 20837008 DOI: 10.1016/j.febslet.2010.09.007  0.96
2010 Wang Y, Jiao X, Kayser F, Liu J, Wang Z, Wanska M, Greenberg J, Weiszmann J, Ge H, Tian H, Wong S, Schwandner R, Lee T, Li Y. The first synthetic agonists of FFA2: Discovery and SAR of phenylacetamides as allosteric modulators. Bioorganic & Medicinal Chemistry Letters. 20: 493-8. PMID 20005104 DOI: 10.1016/j.bmcl.2009.11.112  0.96
2009 Liu J, Wang Y, Sun Y, Marshall D, Miao S, Tonn G, Anders P, Tocker J, Tang HL, Medina J. Tetrahydroquinoline derivatives as CRTH2 antagonists. Bioorganic & Medicinal Chemistry Letters. 19: 6840-4. PMID 19896843 DOI: 10.1016/j.bmcl.2009.10.094  0.96
2009 Liu J, Fu Z, Wang Y, Schmitt M, Huang A, Marshall D, Tonn G, Seitz L, Sullivan T, Lucy Tang H, Collins T, Medina J. Discovery and optimization of CRTH2 and DP dual antagonists. Bioorganic & Medicinal Chemistry Letters. 19: 6419-23. PMID 19804971 DOI: 10.1016/j.bmcl.2009.09.052  0.96
2009 Motani A, Wang Z, Conn M, Siegler K, Zhang Y, Liu Q, Johnstone S, Xu H, Thibault S, Wang Y, Fan P, Connors R, Le H, Xu G, Walker N, et al. Identification and characterization of a non-retinoid ligand for retinol-binding protein 4 which lowers serum retinol-binding protein 4 levels in vivo. The Journal of Biological Chemistry. 284: 7673-80. PMID 19147488 DOI: 10.1074/jbc.M809654200  0.96
2008 Lee T, Schwandner R, Swaminath G, Weiszmann J, Cardozo M, Greenberg J, Jaeckel P, Ge H, Wang Y, Jiao X, Liu J, Kayser F, Tian H, Li Y. Identification and functional characterization of allosteric agonists for the G protein-coupled receptor FFA2. Molecular Pharmacology. 74: 1599-609. PMID 18818303 DOI: 10.1124/mol.108.049536  0.96
2002 Singleton DA, Wang Y, Yang HW, Romo D. Mechanism and origin of stereoselectivity in Lewis acid catalyzed [2 + 2] cycloadditions of ketenes with aldehydes. Angewandte Chemie (International Ed. in English). 41: 1572-5. PMID 19750669  0.96
2002 Wang Y, Romo D. Concise total synthesis of (+)-brefeldin A: a combined beta-lactone/cross-metathesis-based strategy. Organic Letters. 4: 3231-4. PMID 12227756 DOI: 10.1021/ol026438g  0.96
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