Scott E. Warder - Publications

2000 University of Notre Dame, Notre Dame, IN, United States 

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 McDaniel KF, Wang L, Soltwedel T, Fidanze SD, Hasvold LA, Liu D, Mantei RA, Pratt JK, Sheppard GS, Bui MH, Faivre EJ, Huang X, Li L, Lin X, Wang R, ... Warder SE, et al. Discovery of N-(4-(2,4-difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide (ABBV-075/mivebresib), a Potent and Orally Available Bromodomain and Extraterminal domain (BET) Family Bromodomain Inhibitor. Journal of Medicinal Chemistry. PMID 28949521 DOI: 10.1021/acs.jmedchem.7b00746  0.44
2017 Bui MH, Lin X, Albert DH, Li L, Lam LT, Faivre EJ, Warder S, Huang X, Wilcox D, Donawho CK, Sheppard GS, Wang L, Fidanze S, Pratt JK, Liu D, et al. Preclinical characterization of BET family bromodomain inhibitor ABBV-075 suggests combination therapeutic strategies. Cancer Research. PMID 28416490 DOI: 10.1158/0008-5472.CAN-16-1793  0.44
2017 Wang L, Pratt JK, Soltwedel T, Sheppard GS, Fidanze SD, Liu D, Hasvold LA, Mantei RA, Holms JH, McClellan WJ, Wendt MD, Wada CK, Frey RR, Hansen TM, Hubbard R, ... ... Warder SE, et al. Fragment-based, structure-enabled discovery of novel pyridones and pyridone macrocycles as potent bromodomain and extra-terminal domain (BET) family bromodomain inhibitors. Journal of Medicinal Chemistry. PMID 28368119 DOI: 10.1021/acs.jmedchem.7b00017  0.44
2017 Hasvold LA, Sheppard GS, Wang L, Fidanze SD, Liu D, Pratt JK, Mantei RA, Wada CK, Hubbard R, Shen Y, Lin X, Huang X, Warder SE, Wilcox D, Li L, et al. Methylpyrrole inhibitors of BET bromodomains. Bioorganic & Medicinal Chemistry Letters. PMID 28268136 DOI: 10.1016/j.bmcl.2017.02.057  0.44
2015 Tang H, Duggan S, Richardson PL, Marin V, Warder SE, McLoughlin SM. Target Identification of Compounds from a Cell Viability Phenotypic Screen Using a Bead/Lysate-Based Affinity Capture Platform. Journal of Biomolecular Screening. PMID 26676096 DOI: 10.1177/1087057115622431  1
2011 Carr TL, Ciurlionis R, Milicic I, Whitney K, Liguori MJ, Warder SE, Strakhova MI, Blomme EA. Role of cytochrome P450c17α in dibromoacetic acid-induced testicular toxicity in rats. Archives of Toxicology. 85: 513-23. PMID 21046364 DOI: 10.1007/s00204-010-0600-2  1
2010 Shah OJ, Lin X, Li L, Huang X, Li J, Anderson MG, Tang H, Rodriguez LE, Warder SE, McLoughlin S, Chen J, Palma J, Glaser KB, Donawho CK, Fesik SW, et al. Bcl-XL represents a druggable molecular vulnerability during aurora B inhibitor-mediated polyploidization. Proceedings of the National Academy of Sciences of the United States of America. 107: 12634-9. PMID 20616035 DOI: 10.1073/Pnas.0913615107  1
2009 Warder SE, Tucker LA, Strelitzer TJ, McKeegan EM, Meuth JL, Jung PM, Saraf A, Singh B, Lai-Zhang J, Gagne G, Rogers JC. Reducing agent-mediated precipitation of high-abundance plasma proteins. Analytical Biochemistry. 387: 184-93. PMID 19454248 DOI: 10.1016/j.ab.2009.01.013  1
2008 Warder SE, Tucker LA, McLoughlin SM, Strelitzer TJ, Meuth JL, Zhang Q, Sheppard GS, Richardson PL, Lesniewski R, Davidsen SK, Bell RL, Rogers JC, Wang J. Discovery, identification, and characterization of candidate pharmacodynamic markers of methionine aminopeptidase-2 inhibition. Journal of Proteome Research. 7: 4807-20. PMID 18828628 DOI: 10.1021/pr800388p  1
2008 Waring JF, Yang Y, Healan-Greenberg CH, Adler AL, Dickinson R, McNally T, Wang X, Weitzberg M, Xu X, Lisowski A, Warder SE, Gu YG, Zinker BA, Blomme EA, Camp HS. Gene expression analysis in rats treated with experimental acetyl-coenzyme A carboxylase inhibitors suggests interactions with the peroxisome proliferator-activated receptor alpha pathway. The Journal of Pharmacology and Experimental Therapeutics. 324: 507-16. PMID 18025247 DOI: 10.1124/jpet.107.126938  1
2001 Klein RC, Warder SE, Galdzicki Z, Castellino FJ, Prorok M. Kinetic and mechanistic characterization of NMDA receptor antagonism by replacement and truncation variants of the conantokin peptides. Neuropharmacology. 41: 801-10. PMID 11684144 DOI: 10.1016/S0028-3908(01)00119-8  1
2001 Warder SE, Blandl T, Klein RC, Castellino FJ, Prorok M. Amino acid determinants for NMDA receptor inhibition by conantokin-T. Journal of Neurochemistry. 77: 812-22. PMID 11331410 DOI: 10.1046/J.1471-4159.2001.00281.X  1
2000 Schenone MM, Warder SE, Martin JA, Prorok M, Castellino FJ. An internal histidine residue from the bacterial surface protein, PAM, mediates its binding to the kringle-2 domain of human plasminogen. The Journal of Peptide Research : Official Journal of the American Peptide Society. 56: 438-45. PMID 11152303 DOI: 10.1034/J.1399-3011.2000.00810.X  1
2000 Blandl T, Warder SE, Prorok M, Castellino FJ. Structure-function relationships of the NMDA receptor antagonist peptide, conantokin-R. Febs Letters. 470: 139-46. PMID 10734223 DOI: 10.1016/S0014-5793(00)01309-0  1
2000 Schenone MM, Warder SE, Martin JA, Prokok M, Castellino FJ. Binding of RAM-derived peptides to the recombinant kringle 2 domain of human plasminogen Fibrinolysis and Proteolysis. 14: 23.  1
1999 Blandl T, Warder SE, Prorok M, Castellino FJ. Binding of cations to individual gamma-carboxyglutamate residues of conantokin-G and conantokin-T. The Journal of Peptide Research : Official Journal of the American Peptide Society. 53: 453-64. PMID 10406223 DOI: 10.1034/J.1399-3011.1999.00042.X  1
1998 Chen Z, Blandl T, Prorok M, Warder SE, Li L, Zhu Y, Pedersen LG, Ni F, Castellino FJ. Conformational changes in conantokin-G induced upon binding of calcium and magnesium as revealed by NMR structural analysis. The Journal of Biological Chemistry. 273: 16248-58. PMID 9632684 DOI: 10.1074/Jbc.273.26.16248  1
1998 Warder SE, Prorok M, Chen Z, Li L, Zhu Y, Pedersen LG, Ni F, Castellino FJ. The roles of individual gamma-carboxyglutamate residues in the solution structure and cation-dependent properties of conantokin-T. The Journal of Biological Chemistry. 273: 7512-22. PMID 9516452 DOI: 10.1074/Jbc.273.13.7512  1
1997 Warder SE, Chen Z, Zhu Y, Prorok M, Castellino FJ, Ni F. The NMR solution structure of the NMDA receptor antagonist, conantokin-T, in the absence of divalent metal ions. Febs Letters. 411: 19-26. PMID 9247135 DOI: 10.1016/S0014-5793(97)00573-5  1
1996 Prorok M, Warder SE, Blandl T, Castellino FJ. Calcium binding properties of synthetic gamma-carboxyglutamic acid-containing marine cone snail "sleeper" peptides, conantokin-G and conantokin-T. Biochemistry. 35: 16528-34. PMID 8987986 DOI: 10.1021/Bi9621122  1
1996 Prorok M, Geng JP, Warder SE, Castellino FJ. The entire gamma-carboxyglutamic acid- and helical stack-domains of human coagulation factor IX are required for optimal binding to its endothelial cell receptor. International Journal of Peptide and Protein Research. 48: 281-5. PMID 8897096 DOI: 10.1111/J.1399-3011.1996.Tb00842.X  1
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