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Mariana Figuera-Losada - Publications

Affiliations: 
2013- Albert Einstein College of Medicine, New York, New York, United States 
Area:
biochemistry
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10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Figuera-Losada M, Thomas AG, Stathis M, Stockwell BR, Rojas C, Slusher BS. Development of a primary microglia screening assay and its use to characterize inhibition of system xc(-) by erastin and its analogs. Biochemistry and Biophysics Reports. 9: 266-272. PMID 28956014 DOI: 10.1016/J.Bbrep.2016.12.009  0.315
2015 Figuera-Losada M, Stathis M, Dorskind JM, Thomas AG, Bandaru VV, Yoo SW, Westwood NJ, Rogers GW, McArthur JC, Haughey NJ, Slusher BS, Rojas C. Cambinol, a novel inhibitor of neutral sphingomyelinase 2 shows neuroprotective properties. Plos One. 10: e0124481. PMID 26010541 DOI: 10.1371/Journal.Pone.0124481  0.394
2014 Figuera-Losada M, Rojas C, Slusher BS. Inhibition of microglia activation as a phenotypic assay in early drug discovery. Journal of Biomolecular Screening. 19: 17-31. PMID 23945875 DOI: 10.1177/1087057113499406  0.353
2013 Feng Y, Chambers JW, Iqbal S, Koenig M, Park H, Cherry L, Hernandez P, Figuera-Losada M, LoGrasso PV. A small molecule bidentate-binding dual inhibitor probe of the LRRK2 and JNK kinases. Acs Chemical Biology. 8: 1747-54. PMID 23751758 DOI: 10.1021/Cb3006165  0.374
2012 Laughlin JD, Nwachukwu JC, Figuera-Losada M, Cherry L, Nettles KW, LoGrasso PV. Structural mechanisms of allostery and autoinhibition in JNK family kinases. Structure (London, England : 1993). 20: 2174-84. PMID 23142346 DOI: 10.1016/J.Str.2012.09.021  0.467
2012 Figuera-Losada M, LoGrasso PV. Enzyme kinetics and interaction studies for human JNK1β1 and substrates activating transcription factor 2 (ATF2) and c-Jun N-terminal kinase (c-Jun). The Journal of Biological Chemistry. 287: 13291-302. PMID 22351776 DOI: 10.1074/Jbc.M111.323766  0.384
2011 Chambers JW, Cherry L, Laughlin JD, Figuera-Losada M, Lograsso PV. Selective inhibition of mitochondrial JNK signaling achieved using peptide mimicry of the Sab kinase interacting motif-1 (KIM1). Acs Chemical Biology. 6: 808-18. PMID 21563797 DOI: 10.1021/Cb200062A  0.366
2010 Figuera-Losada M, Ranson M, Sanderson-Smith ML, Walker MJ, Castellino FJ, Prorok M. Effects on human plasminogen conformation and activation rate caused by interaction with VEK-30, a peptide derived from the group A streptococcal M-like protein (PAM). Biochimica Et Biophysica Acta. 1804: 1342-9. PMID 20152941 DOI: 10.1016/J.Bbapap.2010.01.019  0.56
2010 Kamenecka T, Jiang R, Song X, Duckett D, Chen W, Ling YY, Habel J, Laughlin JD, Chambers J, Figuera-Losada M, Cameron MD, Lin L, Ruiz CH, LoGrasso PV. Synthesis, biological evaluation, X-ray structure, and pharmacokinetics of aminopyrimidine c-jun-N-terminal kinase (JNK) inhibitors. Journal of Medicinal Chemistry. 53: 419-31. PMID 19947601 DOI: 10.1021/Jm901351F  0.347
2008 Fu Q, Figuera-Losada M, Ploplis VA, Cnudde S, Geiger JH, Prorok M, Castellino FJ. The lack of binding of VEK-30, an internal peptide from the group A streptococcal M-like protein, PAM, to murine plasminogen is due to two amino acid replacements in the plasminogen kringle-2 domain. The Journal of Biological Chemistry. 283: 1580-7. PMID 18039665 DOI: 10.1074/Jbc.M705063200  0.476
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