Ryan A. Altman - Publications

Affiliations: 
2011- Medicinal Chemistry University of Kansas, Lawrence, KS, United States 
Area:
decarboxylative strategies for fluoroalkylation, and the use of fluorinated peptidomimetics to perturb physicochemical and biophysical properties of neuropeptides
Website:
http://medchem.ku.edu/ryan-altman

35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Orsi DL, Douglas JT, Sorrentino JP, Altman RA. Cobalt-Catalyzed Selective Unsymmetrical Dioxidation of -Difluoroalkenes. The Journal of Organic Chemistry. PMID 32697905 DOI: 10.1021/acs.joc.0c00415  0.72
2020 Sorrentino JP, Ambler BR, Altman RA. Late-Stage Conversion of a Metabolically Labile Aryl Methyl Ether-Containing Natural Product to Fluoroalkyl Analogs. The Journal of Organic Chemistry. PMID 32191836 DOI: 10.1021/acs.joc.0c00125  0.96
2020 de Azambuja F, Yang MH, Feoktistova T, Selvaraju M, Brueckner AC, Grove MA, Koley S, Cheong PH, Altman RA. Connecting remote C-H bond functionalization and decarboxylative coupling using simple amines. Nature Chemistry. PMID 32152476 DOI: 10.1038/s41557-020-0428-1  0.88
2019 Orsi DL, Yadav MR, Altman RA. Organocatalytic Strategy for Hydrophenolation of -Difluoroalkenes. Tetrahedron. 75: 4325-4336. PMID 32103843 DOI: 10.1016/j.tet.2019.04.016  0.32
2019 Eeda V, Selvaraju M, Altman RA. Synthesis of Leu-Enkephalin Peptidomimetics Containing Trifluoromethylalkenes as Amide Isopolar Mimics. Journal of Fluorine Chemistry. 218: 90-98. PMID 31061541 DOI: 10.1016/j.jfluchem.2018.12.005  0.44
2019 de Azambuja F, Lovrien SM, Ross P, Ambler BR, Altman RA. Catalytic One-Step Deoxytrifluoromethylation of Alcohols. The Journal of Organic Chemistry. PMID 30632749 DOI: 10.1021/acs.joc.8b03072  0.96
2019 Han C, Alabanza LM, Kelly SM, Orsi DL, Gosselin F, Altman RA. BBDFA: A Practical Reagent for Trifluoromethylation of Allylic and Benzylic Alcohols on Preparative Scale Organic Process Research & Development. 23: 1695-1702. DOI: 10.1021/acs.oprd.9b00201  0.32
2018 Shin I, Ambler BR, Wherritt D, Griffith WP, Maldonado AC, Altman RA, Liu A. Stepwise O-Atom Transfer in Heme-based Tryptophan Dioxygenase: The Role of Substrate Ammonium in the Epoxide Ring Opening. Journal of the American Chemical Society. PMID 29506384 DOI: 10.1021/jacs.8b00262  0.96
2017 Orsi DL, Altman RA. Exploiting the unusual effects of fluorine in methodology. Chemical Communications (Cambridge, England). PMID 28503693 DOI: 10.1039/c7cc02341c  0.32
2017 Orsi DL, Easley BJ, Lick AM, Altman RA. Base Catalysis Enables Access to α,α-Difluoroalkylthioethers. Organic Letters. PMID 28332397 DOI: 10.1021/acs.orglett.7b00386  0.32
2016 Ambler BR, Yang MH, Altman RA. Metal-catalyzed Decarboxylative Fluoroalkylation Reactions. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 27: 2747-2755. PMID 28260839 DOI: 10.1055/s-0036-1588637  0.96
2016 Yang MH, Hunt JR, Sharifi N, Altman RA. Palladium Catalysis Enables Benzylation of α,α-Difluoroketone Enolates. Angewandte Chemie (International Ed. in English). PMID 27312868 DOI: 10.1002/anie.201604149  0.88
2015 Ambler BR, Zhu L, Altman RA. Copper-Catalyzed Synthesis of Trifluoroethylarenes from Benzylic Bromodifluoroacetates. The Journal of Organic Chemistry. PMID 26225803 DOI: 10.1021/acs.joc.5b01343  0.96
2015 Ambler BR, Peddi S, Altman RA. Ligand-Controlled Regioselective Copper-Catalyzed Trifluoromethylation To Generate (Trifluoromethyl)allenes. Organic Letters. 17: 2506-9. PMID 25910053 DOI: 10.1021/acs.orglett.5b01027  0.96
2015 Yang MH, Orsi DL, Altman RA. Ligand-controlled regiodivergent palladium-catalyzed decarboxylative allylation reaction to access α,α-difluoroketones. Angewandte Chemie (International Ed. in English). 54: 2361-5. PMID 25581845 DOI: 10.1002/ange.201410039  0.96
2014 Ambler BR, Peddi S, Altman RA. Copper-Catalyzed Decarboxylative Trifluoromethylation of Propargyl Bromodifluoroacetates. Synthesis. 46: 1938-1946. PMID 25294948 DOI: 10.1055/s-0033-1339128  0.96
2014 Qiao Y, Si T, Yang MH, Altman RA. Metal-free trifluoromethylation of aromatic and heteroaromatic aldehydes and ketones. The Journal of Organic Chemistry. 79: 7122-31. PMID 25001876 DOI: 10.1021/jo501289v  0.96
2014 Qiao Y, Zhu L, Ambler BR, Altman RA. Decarboxylative fluorination strategies for accessing medicinally- relevant products. Current Topics in Medicinal Chemistry. 14: 966-78. PMID 24484421 DOI: 10.2174/1568026614666140202210850  0.96
2014 Altman RA. Editorial: Fluorination and fluorinated compounds in medicinal chemistry. Current Topics in Medicinal Chemistry. 14: 837-9. PMID 24484420  0.96
2014 Altman RA. Fluorination and fluorinated compounds in medicinal chemistry Current Topics in Medicinal Chemistry. 14: 837. DOI: 10.2174/1568026614666140202203407  0.96
2013 Ambler BR, Altman RA. Copper-catalyzed decarboxylative trifluoromethylation of allylic bromodifluoroacetates. Organic Letters. 15: 5578-81. PMID 24117395 DOI: 10.1021/ol402780k  0.96
2013 Zhu L, Liu S, Douglas JT, Altman RA. Copper-mediated deoxygenative trifluoromethylation of benzylic xanthates: generation of a C-CF(3) bond from an O-based electrophile. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 12800-5. PMID 23922222 DOI: 10.1002/chem.201302328  0.96
2013 Yang MH, Matikonda SS, Altman RA. Preparation of fluoroalkenes via the Shapiro reaction: direct access to fluorinated peptidomimetics. Organic Letters. 15: 3894-7. PMID 23879432 DOI: 10.1021/ol401637n  0.96
2010 Altman RA, Nilsson BL, Overman LE, Read de Alaniz J, Rohde JM, Taupin V. Total synthesis of (+)-nankakurines A and B and (±)-5-epi-nankakurine A. The Journal of Organic Chemistry. 75: 7519-34. PMID 20958075 DOI: 10.1021/jo101619d  0.96
2009 Taylor AM, Altman RA, Buchwald SL. Palladium-catalyzed enantioselective alpha-arylation and alpha-vinylation of oxindoles facilitated by an axially chiral P-stereogenic ligand. Journal of the American Chemical Society. 131: 9900-1. PMID 19580273 DOI: 10.1021/ja903880q  1
2008 Altman RA, Hyde AM, Huang X, Buchwald SL. Orthogonal Pd- and Cu-based catalyst systems for C- and N-arylation of oxindoles. Journal of the American Chemical Society. 130: 9613-20. PMID 18588302 DOI: 10.1021/ja803179s  1
2008 Altman RA, Anderson KW, Buchwald SL. Pyrrole-2-carboxylic acid as a ligand for the Cu-catalyzed reactions of primary anilines with aryl halides. The Journal of Organic Chemistry. 73: 5167-9. PMID 18543973 DOI: 10.1021/jo8008676  1
2008 Altman RA, Shafir A, Choi A, Lichtor PA, Buchwald SL. An improved Cu-based catalyst system for the reactions of alcohols with aryl halides. The Journal of Organic Chemistry. 73: 284-6. PMID 18044928 DOI: 10.1021/jo702024p  1
2007 Altman RA, Buchwald SL. Pd-catalyzed Suzuki-Miyaura reactions of aryl halides using bulky biarylmonophosphine ligands. Nature Protocols. 2: 3115-21. PMID 18079711 DOI: 10.1038/nprot.2007.411  1
2007 Altman RA, Fors BP, Buchwald SL. Pd-catalyzed amination reactions of aryl halides using bulky biarylmonophosphine ligands. Nature Protocols. 2: 2881-7. PMID 18007623 DOI: 10.1038/nprot.2007.414  1
2007 Altman RA, Buchwald SL. Cu-catalyzed Goldberg and Ullmann reactions of aryl halides using chelating N- and O-based ligands. Nature Protocols. 2: 2474-9. PMID 17947989 DOI: 10.1038/nprot.2007.364  1
2007 Altman RA, Koval ED, Buchwald SL. Copper-catalyzed N-arylation of imidazoles and benzimidazoles. The Journal of Organic Chemistry. 72: 6190-9. PMID 17625886 DOI: 10.1021/jo070807a  1
2007 Altman RA, Buchwald SL. Cu-catalyzed N- and O-arylation of 2-, 3-, and 4-hydroxypyridines and hydroxyquinolines. Organic Letters. 9: 643-6. PMID 17286371 DOI: 10.1002/chin.200727115  1
2006 Anderson KW, Tundel RE, Ikawa T, Altman RA, Buchwald SL. Monodentate phosphines provide highly active catalysts for Pd-catalyzed C-N bond-forming reactions of heteroaromatic halides/amines and (H)N-heterocycles. Angewandte Chemie (International Ed. in English). 45: 6523-7. PMID 16955526 DOI: 10.1002/anie.200601612  1
2006 Altman RA, Buchwald SL. 4,7-Dimethoxy-1,10-phenanthroline: an excellent ligand for the Cu-catalyzed N-arylation of imidazoles. Organic Letters. 8: 2779-82. PMID 16774255 DOI: 10.1021/ol0608505  1
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