Jane M. Coughlin - Publications

Affiliations: 
2008-2010 Rice University, Houston, TX 

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Vohidov F, Coughlin JM, Ball ZT. Rhodium(II) metallopeptide catalyst design enables fine control in selective functionalization of natural SH3 domains. Angewandte Chemie (International Ed. in English). 54: 4587-91. PMID 25688989 DOI: 10.1002/anie.201411745  1
2014 Coughlin JM, Kundu R, Cooper JC, Ball ZT. Inhibiting prolyl isomerase activity by hybrid organic-inorganic molecules containing rhodium(II) fragments. Bioorganic & Medicinal Chemistry Letters. 24: 5203-6. PMID 25442313 DOI: 10.1016/j.bmcl.2014.09.068  1
2014 Coughlin JM, Rudolf JD, Wendt-Pienkowski E, Wang L, Unsin C, Galm U, Yang D, Tao M, Shen B. BlmB and TlmB provide resistance to the bleomycin family of antitumor antibiotics by N-acetylating metal-free bleomycin, tallysomycin, phleomycin, and zorbamycin. Biochemistry. 53: 6901-9. PMID 25299801 DOI: 10.1021/bi501121e  1
2012 Huang SX, Feng Z, Wang L, Galm U, Wendt-Pienkowski E, Yang D, Tao M, Coughlin JM, Duan Y, Shen B. A designer bleomycin with significantly improved DNA cleavage activity. Journal of the American Chemical Society. 134: 13501-9. PMID 22831455 DOI: 10.1021/ja3056535  1
2012 Chen Z, Vohidov F, Coughlin JM, Stagg LJ, Arold ST, Ladbury JE, Ball ZT. Catalytic protein modification with dirhodium metallopeptides: specificity in designed and natural systems. Journal of the American Chemical Society. 134: 10138-45. PMID 22621321 DOI: 10.1021/ja302284p  1
2011 Galm U, Wendt-Pienkowski E, Wang L, Huang SX, Unsin C, Tao M, Coughlin JM, Shen B. Comparative analysis of the biosynthetic gene clusters and pathways for three structurally related antitumor antibiotics: bleomycin, tallysomycin, and zorbamycin. Journal of Natural Products. 74: 526-36. PMID 21210656 DOI: 10.1021/np1008152  1
2010 Zhao C, Coughlin JM, Ju J, Zhu D, Wendt-Pienkowski E, Zhou X, Wang Z, Shen B, Deng Z. Oxazolomycin biosynthesis in Streptomyces albus JA3453 featuring an "acyltransferase-less" type I polyketide synthase that incorporates two distinct extender units. The Journal of Biological Chemistry. 285: 20097-108. PMID 20406823 DOI: 10.1074/jbc.M109.090092  1
2010 Tao M, Wang L, Wendt-Pienkowski E, Zhang N, Yang D, Galm U, Coughlin JM, Xu Z, Shen B. Functional characterization of tlmH in Streptoalloteichus hindustanus E465-94 ATCC 31158 unveiling new insight into tallysomycin biosynthesis and affording a novel bleomycin analog. Molecular Biosystems. 6: 349-56. PMID 20094654 DOI: 10.1039/b918106g  1
2009 Cheng YQ, Coughlin JM, Lim SK, Shen B. Type I polyketide synthases that require discrete acyltransferases. Methods in Enzymology. 459: 165-86. PMID 19362640 DOI: 10.1016/S0076-6879(09)04608-4  1
2009 Wang L, Tao M, Wendt-Pienkoski E, Galm U, Coughlin JM, Shen B. Functional characterization of tlmK unveiling unstable carbinolamide intermediates in the tallysomycin biosynthetic pathway. The Journal of Biological Chemistry. 284: 8256-64. PMID 19189972 DOI: 10.1074/jbc.M900640200  1
2009 Galm U, Wendt-Pienkowski E, Wang L, George NP, Oh TJ, Yi F, Tao M, Coughlin JM, Shen B. The biosynthetic gene cluster of zorbamycin, a member of the bleomycin family of antitumor antibiotics, from Streptomyces flavoviridis ATCC 21892. Molecular Biosystems. 5: 77-90. PMID 19081934 DOI: 10.1039/b814075h  1
2008 Galm U, Wang L, Wendt-Pienkowski E, Yang R, Liu W, Tao M, Coughlin JM, Shen B. In vivo manipulation of the bleomycin biosynthetic gene cluster in Streptomyces verticillus ATCC15003 revealing new insights into its biosynthetic pathway. The Journal of Biological Chemistry. 283: 28236-45. PMID 18697737 DOI: 10.1074/jbc.M804971200  1
2008 Song D, Coughlin J, Ju J, Zhou X, Shen B, Zhao C, Deng Z. Alternative method for site-directed mutagenesis of complex polyketide synthase in Streptomyces albus JA3453. Acta Biochimica Et Biophysica Sinica. 40: 319-26. PMID 18401530 DOI: 10.1111/j.1745-7270.2008.00408.x  1
2007 Wang L, Yun BS, George NP, Wendt-Pienkowski E, Galm U, Oh TJ, Coughlin JM, Zhang G, Tao M, Shen B. Glycopeptide antitumor antibiotic zorbamycin from Streptomyces flavoviridis ATCC 21892: strain improvement and structure elucidation. Journal of Natural Products. 70: 402-6. PMID 17311457 DOI: 10.1021/np060592k  1
2007 Mohrig JR, Carlson HK, Coughlin JM, Hofmeister GE, McMartin LA, Rowley EG, Trimmer EE, Wild AJ, Schultz SC. Novel syn intramolecular pathway in base-catalyzed 1,2-elimination reactions of beta-acetoxy esters. The Journal of Organic Chemistry. 72: 793-8. PMID 17253797 DOI: 10.1021/jo0619027  1
2007 Tao M, Wang L, Wendt-Pienkowski E, George NP, Galm U, Zhang G, Coughlin JM, Shen B. The tallysomycin biosynthetic gene cluster from Streptoalloteichus hindustanus E465-94 ATCC 31158 unveiling new insights into the biosynthesis of the bleomycin family of antitumor antibiotics. Molecular Biosystems. 3: 60-74. PMID 17216057 DOI: 10.1039/b615284h  1
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