Neil Grimster - Publications

Affiliations: 
2003-2007 Chemistry University of Cambridge, Cambridge, England, United Kingdom 

15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Akçay G, Belmonte MA, Aquila B, Chuaqui C, Hird AW, Lamb ML, Rawlins PB, Su N, Tentarelli S, Grimster NP, Su Q. Inhibition of Mcl-1 through covalent modification of a noncatalytic lysine side chain. Nature Chemical Biology. PMID 27595327 DOI: 10.1038/nchembio.2174  0.56
2014 Kwok SW, Zhang L, Grimster NP, Fokin VV. Catalytic asymmetric transannulation of NH-1,2,3-triazoles with olefins. Angewandte Chemie (International Ed. in English). 53: 3452-6. PMID 24677710 DOI: 10.1002/anie.201306706  0.56
2014 Baranczak A, Connelly S, Liu Y, Choi S, Grimster NP, Powers ET, Wilson IA, Kelly JW. Fluorogenic small molecules requiring reaction with a specific protein to create a fluorescent conjugate for biological imaging-what we know and what we need to learn. Biopolymers. 101: 484-95. PMID 24105107 DOI: 10.1002/bip.22407  0.56
2013 Palhano FL, Lee J, Grimster NP, Kelly JW. Toward the molecular mechanism(s) by which EGCG treatment remodels mature amyloid fibrils. Journal of the American Chemical Society. 135: 7503-10. PMID 23611538 DOI: 10.1021/ja3115696  0.56
2013 Grimster NP, Connelly S, Baranczak A, Dong J, Krasnova LB, Sharpless KB, Powers ET, Wilson IA, Kelly JW. Aromatic sulfonyl fluorides covalently kinetically stabilize transthyretin to prevent amyloidogenesis while affording a fluorescent conjugate. Journal of the American Chemical Society. 135: 5656-68. PMID 23350654 DOI: 10.1021/ja311729d  0.56
2012 Yamauchi JG, Gomez K, Grimster N, Dufouil M, Nemecz A, Fotsing JR, Ho KY, Talley TT, Sharpless KB, Fokin VV, Taylor P. Synthesis of selective agonists for the α7 nicotinic acetylcholine receptor with in situ click-chemistry on acetylcholine-binding protein templates. Molecular Pharmacology. 82: 687-99. PMID 22784805 DOI: 10.1124/mol.112.080291  0.56
2012 Grimster NP, Stump B, Fotsing JR, Weide T, Talley TT, Yamauchi JG, Nemecz Á, Kim C, Ho KY, Sharpless KB, Taylor P, Fokin VV. Generation of candidate ligands for nicotinic acetylcholine receptors via in situ click chemistry with a soluble acetylcholine binding protein template. Journal of the American Chemical Society. 134: 6732-40. PMID 22394239 DOI: 10.1021/ja3001858  0.56
2011 Orwig SD, Tan YL, Grimster NP, Yu Z, Powers ET, Kelly JW, Lieberman RL. Binding of 3,4,5,6-tetrahydroxyazepanes to the acid-β-glucosidase active site: implications for pharmacological chaperone design for Gaucher disease. Biochemistry. 50: 10647-57. PMID 22047104 DOI: 10.1021/bi201619z  0.56
2010 Grimster N, Zhang L, Fokin VV. Synthesis and reactivity of rhodium(II) N-triflyl azavinyl carbenes. Journal of the American Chemical Society. 132: 2510-1. PMID 20131915 DOI: 10.1021/ja910187s  0.56
2010 Grimster NP, Wilton DAA, Chan LKM, Godfrey CRA, Green C, Owen DR, Gaunt MJ. Alkynes to (E)-enolates using tandem catalysis: Stereoselective anti-aldol and syn-[3,3]-rearrangement reactions Tetrahedron. 66: 6429-6436. DOI: 10.1016/j.tet.2010.05.045  0.56
2008 Phipps RJ, Grimster NP, Gaunt MJ. Cu(II)-catalyzed direct and site-selective arylation of indoles under mild conditions. Journal of the American Chemical Society. 130: 8172-4. PMID 18543910 DOI: 10.1021/ja801767s  0.56
2007 Rönn M, McCubbin Q, Winter S, Veige MK, Grimster N, Alorati T, Plamondon L. Expedient synthesis of MLN1251, a CCR5 antagonist for treatment of HIV Organic Process Research and Development. 11: 241-245. DOI: 10.1021/op060245h  0.56
2006 Beck EM, Grimster NP, Hatley R, Gaunt MJ. Mild aerobic oxidative palladium (II) catalyzed C-H bond functionalization: regioselective and switchable C-H alkenylation and annulation of pyrroles. Journal of the American Chemical Society. 128: 2528-9. PMID 16492024 DOI: 10.1021/ja058141u  0.56
2005 Grimster NP, Gauntlett C, Godfrey CR, Gaunt MJ. Palladium-catalyzed intermolecular alkenylation of indoles by solvent-controlled regioselective C-H functionalization. Angewandte Chemie (International Ed. in English). 44: 3125-9. PMID 15828033 DOI: 10.1002/anie.200500468  0.56
2002 Cobb JM, Grimster N, Khan N, Lai JYQ, Payne HJ, Payne LJ, Raynham T, Taylor J. Parallel synthesis of 1,2,4-trisubstituted imidazoles via N-alkyl-N-(β-keto)amides using a carbazate linker Tetrahedron Letters. 43: 7557-7560. DOI: 10.1016/S0040-4039(02)01810-5  0.56
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