Year |
Citation |
Score |
2022 |
Weber S, Ramirez CM, Doerfler W. Ubiquitous Micro-Modular Homologies among Genomes from Viruses to Bacteria to Human Mitochondrial DNA: Platforms for Recombination during Evolution? Viruses. 14. PMID 35632627 DOI: 10.3390/v14050885 |
0.312 |
|
2021 |
Doerfler W. Adenoviral Vector DNA- and SARS-CoV-2 mRNA-Based Covid-19 Vaccines: Possible Integration into the Human Genome - Are Adenoviral Genes Expressed in Vector-based Vaccines? Virus Research. 302: 198466. PMID 34087261 DOI: 10.1016/j.virusres.2021.198466 |
0.368 |
|
2020 |
Doerfler W. Essential concepts are missing: Foreign DNA in food invades the organisms' cells and can lead to stochastic epigenetic alterations with a wide range of possible pathogenetic consequences. Clinical Epigenetics. 12: 21. PMID 32033622 DOI: 10.1186/s13148-020-0813-z |
0.42 |
|
2018 |
Doerfler W, Weber S, Naumann A. Review - EPIGENETICS, 2018 Inheritable Epigenetic Response towards Foreign DNA Entry by Mammalian Host Cells: A Guardian of Genomic Stability. Epigenetics. PMID 30458693 DOI: 10.1080/15592294.2018.1549463 |
0.41 |
|
2018 |
Weber S, Hakobyan A, Zakaryan H, Doerfler W. Intracellular African swine fever virus DNA remains unmethylated in infected Vero cells. Epigenomics. PMID 29327614 DOI: 10.2217/epi-2017-0131 |
0.389 |
|
2016 |
Doerfler W. Beware of manipulations on the genome: epigenetic destabilization through (foreign) DNA insertions. Epigenomics. PMID 26997469 DOI: 10.2217/epi-2016-0019 |
0.431 |
|
2016 |
Weber S, Hofmann A, Naumann A, Hoffmann P, Doerfler W. Epigenetic alterations upon the insertion of foreign DNA into mammalian Genomes: Oncogenesis and evolution Epigenetics and Human Health. 123-143. DOI: 10.1007/978-3-319-27186-6_7 |
0.418 |
|
2015 |
Weber S, Jung S, Doerfler W. DNA methylation and transcription in HERV (K, W, E) and LINE sequences remain unchanged upon foreign DNA insertions. Epigenomics. PMID 26627183 DOI: 10.2217/epi.15.109 |
0.415 |
|
2015 |
Weber S, Hofmann A, Herms S, Hoffmann P, Doerfler W. Destabilization of the human epigenome: consequences of foreign DNA insertions. Epigenomics. 1-11. PMID 26088384 DOI: 10.2217/epi.15.40 |
0.473 |
|
2014 |
Naumann A, Kraus C, Hoogeveen A, Ramirez CM, Doerfler W. Stable DNA methylation boundaries and expanded trinucleotide repeats: role of DNA insertions. Journal of Molecular Biology. 426: 2554-66. PMID 24816393 DOI: 10.1016/j.jmb.2014.04.025 |
0.348 |
|
2014 |
Doerfler W. Foreign DNA Integration and Its Implications via Epigenetic Mechanisms: Oncology and Evolution Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.00010-6 |
0.409 |
|
2014 |
Doerfler W. The impact of foreign DNA integration on tumor biology and evolution via epigenetic alterations Patho-Epigenetics of Disease. 1-14. DOI: 10.1007/978-1-4614-3345-3_1 |
0.336 |
|
2012 |
Doerfler W. Impact of foreign DNA integration on tumor biology and on evolution via epigenetic alterations. Epigenomics. 4: 41-9. PMID 22332657 DOI: 10.2217/epi.11.111 |
0.411 |
|
2011 |
Doerfler W. Epigenetic consequences of foreign DNA insertions: de novo methylation and global alterations of methylation patterns in recipient genomes. Reviews in Medical Virology. 21: 336-46. PMID 21793096 DOI: 10.1002/rmv.698 |
0.433 |
|
2011 |
Doerfler W, Naumann A, Hochstein N, Weber S. DNA methylation profiles in the 5'-upstream region of the human fmr1 promoter and in an adenovirus transgenome Handbook of Epigenetics. 495-509. DOI: 10.1016/B978-0-12-375709-8.00030-7 |
0.405 |
|
2010 |
Doerfler W. DNA--a molecule in search of additional functions: recipient of pool wave emissions? A hypothesis. Medical Hypotheses. 75: 291-3. PMID 20356684 DOI: 10.1016/j.mehy.2010.03.006 |
0.389 |
|
2010 |
Naumann A, Hochstein N, Weber S, Fanning E, Doerfler W. A Distinct DNA-Methylation Boundary in the 5′- Upstream Sequence of the FMR1 Promoter Binds Nuclear Proteins and Is Lost in Fragile X Syndrome (DOI:10.1016/j.ajhg.2009.09.018) American Journal of Human Genetics. 86: 98-100. DOI: 10.1016/j.ajhg.2009.12.004 |
0.604 |
|
2009 |
Naumann A, Hochstein N, Weber S, Fanning E, Doerfler W. A distinct DNA-methylation boundary in the 5'- upstream sequence of the FMR1 promoter binds nuclear proteins and is lost in fragile X syndrome. American Journal of Human Genetics. 85: 606-16. PMID 19853235 DOI: 10.1016/J.Ajhg.2009.09.018 |
0.59 |
|
2009 |
Doerfler W. Epigenetic mechanisms in human adenovirus type 12 oncogenesis. Seminars in Cancer Biology. 19: 136-43. PMID 19429476 DOI: 10.1016/j.semcancer.2009.02.009 |
0.424 |
|
2008 |
Doerfler W. In pursuit of the first recognized epigenetic signal--DNA methylation: a 1976 to 2008 synopsis. Epigenetics : Official Journal of the Dna Methylation Society. 3: 125-33. PMID 18487948 |
0.378 |
|
2008 |
Hochstein N, Webb D, Hösel M, Seidel W, Auerochs S, Doerfler W. Human CAR gene expression in nonpermissive hamster cells boosts entry of type 12 adenovirions and nuclear import of viral DNA. Journal of Virology. 82: 4159-63. PMID 18256153 DOI: 10.1128/JVI.02657-07 |
0.382 |
|
2007 |
Doerfler W. Human adenovirus type 12: crossing species barriers to immortalize the viral genome. Methods in Molecular Medicine. 131: 197-211. PMID 17656784 |
0.355 |
|
2007 |
Hochstein N, Muiznieks I, Mangel L, Brondke H, Doerfler W. Epigenetic status of an adenovirus type 12 transgenome upon long-term cultivation in hamster cells. Journal of Virology. 81: 5349-61. PMID 17344292 DOI: 10.1128/JVI.02624-06 |
0.388 |
|
2007 |
Gray SJ, Gerhardt J, Doerfler W, Small LE, Fanning E. An origin of DNA replication in the promoter region of the human fragile X mental retardation (FMR1) gene. Molecular and Cellular Biology. 27: 426-37. PMID 17101793 DOI: 10.1128/Mcb.01382-06 |
0.684 |
|
2006 |
Doerfler W. De novo methylation, long-term promoter silencing, methylation patterns in the human genome, and consequences of foreign DNA insertion. Current Topics in Microbiology and Immunology. 301: 125-75. PMID 16570847 |
0.428 |
|
2006 |
Doerfler W. The almost-forgotten fifth nucleotide in DNA: an introduction. Current Topics in Microbiology and Immunology. 301: 3-18. PMID 16570843 DOI: 10.1007/3-540-31390-7_1 |
0.494 |
|
2005 |
Remus R, Kanzaki A, Yawata A, Wada H, Nakanishi H, Sugihara T, Zeschnigk M, Zuther I, Schmitz B, Naumann F, Doerfler W, Yawata Y. Relationships between DNA methylation and expression in erythrocyte membrane protein (band 3, protein 4.2, and beta-spectrin) genes during human erythroid development and differentiation. International Journal of Hematology. 82: 422-9. PMID 16533746 DOI: 10.1532/IJH97.05058 |
0.361 |
|
2005 |
Remus R, Kanzaki A, Yawata A, Nakanishi H, Wada H, Sugihara T, Zeschnigk M, Zuther I, Schmitz B, Naumann F, Doerfler W, Yawata Y. DNA methylation in promoter regions of red cell membrane protein genes in healthy individuals and patients with hereditary membrane disorders. International Journal of Hematology. 81: 385-95. PMID 16158818 DOI: 10.1532/IJH97.04171 |
0.35 |
|
2005 |
Doerfler W. On the biological significance of DNA methylation. Biochemistry. Biokhimii͡A. 70: 505-24. PMID 15948705 DOI: 10.1007/s10541-005-0145-9 |
0.455 |
|
2005 |
Doerfler W. DNA methylation - An important genetic signal in biology and pathogenesis | DNA-methylierung - Ein wichtiges genetisches signal in biologie und pathogenese Medizinische Genetik. 17: 260-264. |
0.387 |
|
2004 |
Wronka G, Bernardi G, Doerfler W. Localization of integrated adenovirus DNA in the hamster genome. Cellular and Molecular Life Sciences : Cmls. 61: 2983-90. PMID 15583860 DOI: 10.1007/S00018-004-4294-6 |
0.489 |
|
2004 |
Mende Y, Schneider PM, Baldus SE, Doerfler W. PCR-screening of human esophageal and bronchial cancers reveals absence of adenoviral DNA sequences. Virus Research. 104: 81-5. PMID 15177895 DOI: 10.1016/j.virusres.2004.02.039 |
0.407 |
|
2003 |
Vardimon L, Günthert U, Doerfler W. In vitro methylation of the BsuRI (5'-GGCC-3') sites in the E2a region of adenovirus type 2 DNA does not affect expression in Xenopus laevis oocytes. Molecular and Cellular Biology. 2: 1574-80. PMID 14582198 DOI: 10.1128/MCB.2.12.1574 |
0.433 |
|
2003 |
Palka-Santini M, Schwarz-Herzke B, Hösel M, Renz D, Auerochs S, Brondke H, Doerfler W. The gastrointestinal tract as the portal of entry for foreign macromolecules: fate of DNA and proteins. Molecular Genetics and Genomics : Mgg. 270: 201-15. PMID 12938039 DOI: 10.1007/s00438-003-0907-2 |
0.466 |
|
2003 |
Hösel M, Webb D, Schröer J, Doerfler W. The abortive infection of Syrian hamster cells with human adenovirus type 12. Current Topics in Microbiology and Immunology. 272: 415-40. PMID 12747558 |
0.307 |
|
2002 |
Wronka G, Fechteler K, Schmitz B, Doerfler W. Integrative recombination between adenovirus type 12 DNA and mammalian DNA in a cell-free system: joining by short sequence homologies. Virus Research. 90: 225-42. PMID 12457977 DOI: 10.1016/S0168-1702(02)00201-0 |
0.471 |
|
2002 |
Palka L, Palka-Santini ME, Chambon S, Renz D, Maurer P, Doerfler W. Amyloglucosidase suppresses interference by glycogen in the quantification of DNA using the Hoechst 33258 dye. Biotechniques. 32: 1250,1252,1254,1256. PMID 12074153 |
0.457 |
|
2001 |
Doerfler W, Remus R, Müller K, Heller H, Hohlweg U, Schubbert R. The fate of foreign DNA in mammalian cells and organisms. Developments in Biologicals. 106: 89-97; discussion 14. PMID 11761272 |
0.423 |
|
2001 |
Doerfler W, Hohlweg U, Müller K, Remus R, Heller H, Hertz J. Foreign DNA integration--perturbations of the genome--oncogenesis. Annals of the New York Academy of Sciences. 945: 276-88. PMID 11708490 |
0.518 |
|
2001 |
Hösel M, Schröer J, Webb D, Jaroshevskaja E, Doerfler W. Cellular and early viral factors in the interaction of adenovirus type 12 with hamster cells: the abortive response. Virus Research. 81: 1-16. PMID 11682120 DOI: 10.1016/S0168-1702(01)00242-8 |
0.303 |
|
2001 |
Hösel M, Webb D, Schröer J, Schmitz B, Doerfler W. Overexpression of the adenovirus type 12 (Ad12) pTP or E1A gene facilitates Ad12 DNA replication in nonpermissive BHK21 hamster cells. Journal of Virology. 75: 10041-53. PMID 11581373 DOI: 10.1128/JVI.75.21.10041-10053.2001 |
0.333 |
|
2001 |
Hohlweg U, Doerfler W. On the fate of plant or other foreign genes upon the uptake in food or after intramuscular injection in mice. Molecular Genetics and Genomics : Mgg. 265: 225-33. PMID 11361332 |
0.431 |
|
2001 |
Müller K, Heller H, Doerfler W. Foreign DNA integration. Genome-wide perturbations of methylation and transcription in the recipient genomes. The Journal of Biological Chemistry. 276: 14271-8. PMID 11278495 DOI: 10.1074/jbc.M009380200 |
0.321 |
|
2001 |
Santini MP, Renz D, Doerfler W. A comparison of methods to extract pure DNA from mammalian intestinal contents and from feces Gene Function & Disease. 2: 51-57. DOI: 10.1002/1438-826X(20018)2:1<51::AID-GNFD51>3.0.CO;2-0 |
0.337 |
|
2001 |
Remus R, Zeschnigk M, Zuther I, Kanzaki A, Wada H, Yawata A, Muiznieks I, Schmitz B, Schell G, Yawata Y, Doerfler W. The state of DNA methylation in the promoter regions of the human red cell membrane protein (band 3, protein 4.2, andβ-spectrin) genes Gene Function & Disease. 2: 171-184. DOI: 10.1002/1438-826X(200112)2:4<171::AID-GNFD171>3.0.CO;2-O |
0.325 |
|
2000 |
Müller K, Doerfler W. Methylation-sensitive amplicon subtraction: a novel method to isolate differentially methylated DNA sequences in complex genomes Gene Function & Disease. 1: 154-160. DOI: 10.1002/1438-826X(200010)1:3/4<154::AID-GNFD154>3.0.CO;2-O |
0.322 |
|
1999 |
Pfeffer A, Schubbert R, Orend G, Hilger-Eversheim K, Doerfler W. Integrated viral genomes can be lost from adenovirus type 12-induced hamster tumor cells in a clone-specific, multistep process with retention of the oncogenic phenotype. Virus Research. 59: 113-27. PMID 10854170 DOI: 10.1016/S0168-1702(98)00131-2 |
0.369 |
|
1999 |
Hertz JM, Schell G, Doerfler W. Factors affecting de novo methylation of foreign DNA in mouse embryonic stem cells. The Journal of Biological Chemistry. 274: 24232-40. PMID 10446198 DOI: 10.1074/jbc.274.34.24232 |
0.477 |
|
1999 |
Remus R, Kämmer C, Heller H, Schmitz B, Schell G, Doerfler W. Insertion of foreign DNA into an established mammalian genome can alter the methylation of cellular DNA sequences. Journal of Virology. 73: 1010-22. PMID 9882302 |
0.5 |
|
1998 |
Doerfler W, Schubbert R, Heller H, Hertz J, Remus R, Schröer J, Kämmer C, Hilger-Eversheim K, Gerhardt U, Schmitz B, Renz D, Schell G. Foreign DNA in mammalian systems. Apmis. Supplementum. 84: 62-8. PMID 9850684 DOI: 10.1002/9783527613465 |
0.405 |
|
1998 |
Munnes M, Patrone G, Schmitz B, Romeo G, Doerfler W. A 5'-CG-3'-rich region in the promoter of the transcriptionally frequently silenced RET protooncogene lacks methylated cytidine residues. Oncogene. 17: 2573-83. PMID 9840920 DOI: 10.1038/sj.onc.1202165 |
0.351 |
|
1998 |
Schubbert R, Hohlweg U, Renz D, Doerfler W. On the fate of orally ingested foreign DNA in mice: chromosomal association and placental transmission to the fetus. Molecular & General Genetics : Mgg. 259: 569-76. PMID 9819049 DOI: 10.1007/s004380050850 |
0.47 |
|
1998 |
Doerfler W, Schubbert R. Uptake of foreign DNA from the environment: the gastrointestinal tract and the placenta as portals of entry. Wiener Klinische Wochenschrift. 110: 40-4. PMID 9531678 |
0.464 |
|
1998 |
Muiznieks I, Doerfler W. DNA fragments with specific nucleotide sequences in their single-stranded termini exhibit unusual electrophoretic mobilities. Nucleic Acids Research. 26: 1899-905. PMID 9518482 DOI: 10.1093/nar/26.8.1899 |
0.442 |
|
1997 |
Schröer J, Hölker I, Doerfler W. Adenovirus type 12 DNA firmly associates with mammalian chromosomes early after virus infection or after DNA transfer by the addition of DNA to the cell culture medium. Journal of Virology. 71: 7923-32. PMID 9311883 |
0.422 |
|
1997 |
Doerfler W, Schubbert R, Heller H, Kämmer C, Hilger-Eversheim K, Knoblauch M, Remus R. Integration of foreign DNA and its consequences in mammalian systems. Trends in Biotechnology. 15: 297-301. PMID 9263477 DOI: 10.1016/S0167-7799(97)01061-5 |
0.507 |
|
1997 |
Hilger-Eversheim K, Doerfler W. Clonal origin of adenovirus type 12-induced hamster tumors: nonspecific chromosomal integration sites of viral DNA. Cancer Research. 57: 3001-9. PMID 9230215 |
0.344 |
|
1997 |
Schubbert R, Renz D, Schmitz B, Doerfler W. Foreign (M13) DNA ingested by mice reaches peripheral leukocytes, spleen, and liver via the intestinal wall mucosa and can be covalently linked to mouse DNA. Proceedings of the National Academy of Sciences of the United States of America. 94: 961-6. PMID 9023365 DOI: 10.1073/pnas.94.3.961 |
0.462 |
|
1996 |
Doerfler W. A new concept in (adenoviral) oncogenesis: integration of foreign DNA and its consequences. Biochimica Et Biophysica Acta. 1288: F79-99. PMID 8876634 DOI: 10.1016/0304-419X(96)00024-8 |
0.533 |
|
1996 |
Koetsier PA, Doerfler W. Influence of mouse-strain-specific factors on position-dependent transgene DNA methylation patterns. Acta Geneticae Medicae Et Gemellologiae. 45: 243-4. PMID 8872039 |
0.327 |
|
1996 |
Kochanek S, Hosokawa K, Schiedner G, Renz D, Doerfler W. DNA methylation in the promoter of ribosomal RNA genes in human cells as determined by genomic sequencing. Febs Letters. 388: 192-4. PMID 8690085 DOI: 10.1016/0014-5793(96)00506-6 |
0.378 |
|
1996 |
Knoblauch M, Schröer J, Schmitz B, Doerfler W. The structure of adenovirus type 12 DNA integration sites in the hamster cell genome. Journal of Virology. 70: 3788-96. PMID 8648714 |
0.41 |
|
1996 |
Deissler H, Behn-Krappa A, Doerfler W. Purification of nuclear proteins from human HeLa cells that bind specifically to the unstable tandem repeat (CGG)n in the human FMR1 gene. The Journal of Biological Chemistry. 271: 4327-34. PMID 8626781 |
0.333 |
|
1995 |
Orend G, Knoblauch M, Doerfler W. Selective loss of unmethylated segments of integrated Ad12 genomes in revertants of the adenovirus type 12-transformed cell line T637. Virus Research. 38: 261-7. PMID 8578863 DOI: 10.1016/0168-1702(95)00044-Q |
0.375 |
|
1995 |
Munnes M, Schetter C, Hölker I, Doerfler W. A fully 5'-CG-3' but not a 5'-CCGG-3' methylated late frog virus 3 promoter retains activity. Journal of Virology. 69: 2240-7. PMID 7884871 |
0.437 |
|
1995 |
Orend G, Knoblauch M, Kämmer C, Tjia ST, Schmitz B, Linkwitz A, Meyer G, Maas J, Doerfler W. The initiation of de novo methylation of foreign DNA integrated into a mammalian genome is not exclusively targeted by nucleotide sequence. Journal of Virology. 69: 1226-42. PMID 7815498 |
0.373 |
|
1995 |
Doerfler W. The insertion of foreign DNA into mammalian genomes and its consequences: a concept in oncogenesis. Advances in Cancer Research. 66: 313-44. PMID 7793319 |
0.419 |
|
1995 |
Heller H, Kämmer C, Wilgenbus P, Doerfler W. Chromosomal insertion of foreign (adenovirus type 12, plasmid, or bacteriophage lambda) DNA is associated with enhanced methylation of cellular DNA segments. Proceedings of the National Academy of Sciences of the United States of America. 92: 5515-9. PMID 7777540 DOI: 10.1073/pnas.92.12.5515 |
0.507 |
|
1995 |
Kämmer C, Doerfler W. Genomic sequencing reveals absence of DNA methylation in the major late promoter of adenovirus type 2 DNA in the virion and in productively infected cells. Febs Letters. 362: 301-5. PMID 7729517 DOI: 10.1016/0014-5793(95)00248-8 |
0.464 |
|
1995 |
Doerfler W, Orend G, Schubbert R, Fechteler K, Heller H, Wilgenbus P, Schröer J. On the insertion of foreign DNA into mammalian genomes: mechanism and consequences. Gene. 157: 241-5. PMID 7607499 DOI: 10.1016/0378-1119(95)00080-P |
0.498 |
|
1995 |
Sprengel J, Schmitz B, Heuss-Neitzel D, Doerfler W. The complete nucleotide sequence of the DNA of human adenovirus type 12. Current Topics in Microbiology and Immunology. 199: 189-274. PMID 7555068 |
0.409 |
|
1995 |
Fechteler K, Tatzelt J, Huppertz S, Wilgenbus P, Doerfler W. The mechanism of adenovirus DNA integration: studies in a cell-free system. Current Topics in Microbiology and Immunology. 199: 109-37. PMID 7555065 |
0.42 |
|
1995 |
Deissler H, Genç B, Doerfler W. Restriction endonuclease BsoFI is sensitive to the 5'-methylation of deoxycytidines in its recognition sequence. Nucleic Acids Research. 23: 4227-8. PMID 7501438 |
0.363 |
|
1995 |
Doerfler W. Uptake of foreign DNA by mammalian cells via the gastrointestinal tract in mice: methylation of foreign DNA--a cellular defense mechanism. Current Topics in Microbiology and Immunology. 197: 209-24. PMID 7493494 |
0.447 |
|
1995 |
Doerfler W, Fechteler K, Heller H, Kämmer C, Knoblauch M, Orend G, Schubbert R. Integration of foreign DNA into the mammalian genome: Mechanism and consequences Journal of Cancer Research and Clinical Oncology. 121: S25-S25. DOI: 10.1007/BF02559853 |
0.387 |
|
1994 |
Sprengel J, Schmitz B, Heuss-Neitzel D, Zock C, Doerfler W. Nucleotide sequence of human adenovirus type 12 DNA: comparative functional analysis. Journal of Virology. 68: 379-89. PMID 8254750 |
0.43 |
|
1994 |
Orend G, Linkwitz A, Doerfler W. Selective sites of adenovirus (foreign) DNA integration into the hamster genome: Changes in integration patterns Journal of Virology. 68: 187-194. PMID 8254728 |
0.382 |
|
1994 |
Karlin S, Doerfler W, Cardon LR. Why is CpG suppressed in the genomes of virtually all small eukaryotic viruses but not in those of large eukaryotic viruses? Journal of Virology. 68: 2889-97. PMID 8151759 DOI: 10.1128/Jvi.68.5.2889-2897.1994 |
0.357 |
|
1994 |
Schubbert R, Lettmann C, Doerfler W. Ingested foreign (phage M13) DNA survives transiently in the gastrointestinal tract and enters the bloodstream of mice. Molecular & General Genetics : Mgg. 242: 495-504. PMID 8121408 DOI: 10.1007/BF00285273 |
0.431 |
|
1994 |
Behn-Krappa A, Doerfler W. Enzymatic amplification of synthetic oligodeoxyribonucleotides: implications for triplet repeat expansions in the human genome. Human Mutation. 3: 19-24. PMID 8118462 DOI: 10.1002/humu.1380030104 |
0.319 |
|
1994 |
Kochanek S, Renz D, Doerfler W. Variability in allelic DNA methylation in spermatozoa. Human Genetics. 94: 203-6. PMID 8045570 DOI: 10.1007/BF00202872 |
0.428 |
|
1994 |
Muiznieks I, Doerfler W. The topology of the promoter of RNA polymerase II- and III-transcribed genes is modified by the methylation of 5'-CG-3' dinucleotides. Nucleic Acids Research. 22: 2568-75. PMID 8041619 |
0.519 |
|
1993 |
Kochanek S, Renz D, Doerfler W. Probing DNA-protein interactions in vitro with the CpG DNA methyltransferase Nucleic Acids Research. 21: 2339-2342. PMID 8506131 |
0.528 |
|
1993 |
Zock C, Iselt A, Doerfler W. A unique mitigator sequence determines the species specificity of the major late promoter in adenovirus Type 12 DNA Journal of Virology. 67: 682-693. PMID 8419643 |
0.364 |
|
1993 |
Doerfler W. Patterns of de novo DNA methylation and promoter inhibition: studies on the adenovirus and the human genomes Exs. 64: 262-299. PMID 8418951 |
0.365 |
|
1993 |
Kochanek S, Renz D, Doerfler W. DNA methylation in the Alu sequences of diploid and haploid primary human cells Embo Journal. 12: 1141-1151. PMID 8384552 |
0.353 |
|
1993 |
Koetsier PA, Schorr J, Doerfler W. A rapid optimized protocol for downward alkaline Southern blotting of DNA Biotechniques. 15: 260+262. PMID 8373591 |
0.332 |
|
1993 |
Behn-Krappa A, Doerfler W. The state of DNA methylation in the promoter and exon 1 regions of the human gene for the interleukin-2 receptor alpha chain (IL-2R alpha) in various cell types. Human Molecular Genetics. 2: 993-9. PMID 8364583 |
0.329 |
|
1993 |
Tatzelt J, Fechteler K, Langenbach P, Doerfler W. Fractionated nuclear extracts from hamster cells catalyze cell-free recombination at selective sequences between adenovirus DNA and a hamster preinsertion site Proceedings of the National Academy of Sciences of the United States of America. 90: 7356-7360. PMID 8346256 |
0.441 |
|
1993 |
Schorr J, Doerfler W. Non-homologous recombination between adenovirus and AcNPV DNA fragments in cell-free extracts from insect Spodoptera frugiperda nuclei Virus Research. 28: 153-170. PMID 8317144 DOI: 10.1016/0168-1702(93)90133-8 |
0.398 |
|
1993 |
Kochanek S, Renz D, Doerfler W. Differences in the accessibility of methylated and unmethylated DNA to DNase I Nucleic Acids Research. 21: 5843-5845. PMID 8290342 |
0.504 |
|
1993 |
Doerfler W. Adenoviral DNA integration and changes in DNA methylation patterns: a different view of insertional mutagenesis Progress in Nucleic Acid Research and Molecular Biology. 46: 1-36. PMID 8234781 |
0.46 |
|
1993 |
Schetter C, Grünemann B, Hölker I, Doerfler W. Patterns of frog virus 3 DNA methylation and DNA methyltransferase activity in nuclei of infected cells Journal of Virology. 67: 6973-6978. PMID 8230420 |
0.519 |
|
1993 |
Doerfler W, Böhm P. Malignant transformation by DNA viruses. Molecular mechanisms. Biomedicine & Pharmacotherapy. 47: 49. DOI: 10.1016/0753-3322(93)90050-U |
0.348 |
|
1992 |
Doerfler W. DNA methylation: eukaryotic defense against the transcription of foreign genes? Microbial Pathogenesis. 12: 1-8. PMID 1560750 DOI: 10.1016/0882-4010(92)90060-2 |
0.43 |
|
1992 |
Toth M, Doerfler W, Shenk T. Adenovirus DNA replication facilitates binding of the MLTF/USF transcription factor to the viral major late promoter within infected cells Nucleic Acids Research. 20: 5143-5148. PMID 1408829 DOI: 10.1093/Nar/20.19.5143 |
0.544 |
|
1992 |
Tatzelt J, Scholz B, Fechteier K, Jessberger R, Doerfler W. Recombination between adenovirus type 12 DNA and a hamster preinsertion sequence in a cell-free system. Patch homologies and fractionation of nuclear extracts Journal of Molecular Biology. 226: 117-126. PMID 1320127 DOI: 10.1016/0022-2836(92)90128-7 |
0.41 |
|
1991 |
Achten S, Behn-Krappa A, Jücker M, Sprengel J, Hölker I, Schmitz B, Tesch H, Diehl V, Doerfler W. Patterns of DNA methylation in selected human genes in different Hodgkin's lymphoma and leukemia cell lines and in normal human lymphocytes. Cancer Research. 51: 3702-9. PMID 2065326 |
0.426 |
|
1991 |
Kochanek S, Radbruch A, Tesch H, Renz D, Doerfler W. DNA methylation profiles in the human genes for tumor necrosis factors α and β in subpopulations of leukocytes and in leukemias Proceedings of the National Academy of Sciences of the United States of America. 88: 5759-5763. PMID 2062856 DOI: 10.1073/Pnas.88.13.5759 |
0.325 |
|
1991 |
Doerfler W. Abortive infection and malignant transformation by adenoviruses: integration of viral DNA and control of viral gene expression by specific patterns of DNA methylation Advances in Virus Research. 39: 89-128. PMID 2038956 |
0.448 |
|
1991 |
Jüttermann R, Hosokawa K, Kochanek S, Doerfler W. Adenovirus type 2 VAI RNA transcription by polymerase III is blocked by sequence-specific methylation Journal of Virology. 65: 1735-1742. PMID 2002541 |
0.356 |
|
1991 |
Guangming X, Schorr J, Tjia ST, Doerfler W. Heterologous recombination between Autographa californica nuclear polyhedrosis virus DNA and foreign DNA in non-polyhedrin segments of the viral genome Virus Research. 21: 65-85. PMID 1962504 DOI: 10.1016/0168-1702(91)90072-4 |
0.446 |
|
1991 |
Doerfler W. Patterns of Dna Methylation — Evolutionary Vestiges of Foreign Dna Inactivation as a Host Defense Mechanism a Proposal | Muster der DNA-Methylierung — Evolutionäre Spuren eines Abwehrmechanismus gegenüber fremder DNA in den Rezipientenzellen - eine Übersicht Biological Chemistry Hoppe-Seyler. 372: 557-564. PMID 1958315 DOI: 10.1515/bchm3.1991.372.2.557 |
0.513 |
|
1991 |
Lettmann C, Schmitz B, Doerfler W. Persistence or loss of preimposed methylation patterns and de novo methylation of foreign DNA integrated in transgenic mice Nucleic Acids Research. 19: 7131-7137. PMID 1837354 |
0.39 |
|
1991 |
Behn-Krappa A, Hölker I, Sandaradura de Silva U, Doerfler W. Patterns of DNA methylation are indistinguishable in different individuals over a wide range of human DNA sequences. Genomics. 11: 1-7. PMID 1722485 DOI: 10.1016/0888-7543(91)90095-V |
0.441 |
|
1991 |
Orend G, Kuhlmann I, Doerfler W. Spreading of DNA methylation across integrated foreign (Adenovirus Type 12) genomes in mammalian cells Journal of Virology. 65: 4301-4308. PMID 1712860 |
0.466 |
|
1991 |
Hermann R, Doerfler W. Interference with protein binding at AP2 sites by sequence-specific methylation in the late E2A promoter of adenovirus type 2 DNA Febs Letters. 286: 238. DOI: 10.1016/0014-5793(91)80391-F |
0.394 |
|
1990 |
Kochanek S, Toth M, Dehmel A, Renz D, Doerfler W. Interindividual concordance of methylation profiles in human genes for tumor necrosis factors α and β Proceedings of the National Academy of Sciences of the United States of America. 87: 8830-8834. PMID 2247453 DOI: 10.1073/pnas.87.22.8830 |
0.399 |
|
1990 |
Doerfler W. Ernst Klenk lecture, November 7, 1988. Patterns of DNA methylation in the mammalian genome Biological Chemistry Hoppe-Seyler. 371: 455-463. PMID 2202331 |
0.379 |
|
1990 |
Doerfler W, Toth M, Kochanek S, Achten S, Freisem-Rabien U, Behn-Krappa A, Orend G. Eukaryotic DNA methylation: facts and problems. Febs Letters. 268: 329-33. PMID 2200712 DOI: 10.1016/0014-5793(90)81280-2 |
0.449 |
|
1990 |
Zock C, Doerfler W. A mitigator sequence in the downstream region of the major late promoter of adenovirus type 12 DNA Embo Journal. 9: 1615-1623. PMID 2158446 |
0.3 |
|
1990 |
Schetter C, Oellig C, Doerfler W. An insertion of insect cell DNA in the 81-map-unit segment of autographa californica nuclear polyhedrosis vires DNA Journal of Virology. 64: 1844-1850. PMID 2157067 |
0.437 |
|
1990 |
Toth M, Müller U, Doerfler W. Establishment of de novo DNA methylation patterns. Transcription factor binding and deoxycytidine methylation at CpG and non-CpG sequences in an integrated adenovirus promoter Journal of Molecular Biology. 214: 673-683. PMID 2143784 DOI: 10.1016/0022-2836(90)90285-T |
0.365 |
|
1990 |
Doerfler W. The significance of DNA methylation patterns: promoter inhibition by sequence-specific methylation is one functional consequence Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 326: 253-265. PMID 1968662 |
0.435 |
|
1989 |
Jessberger R, Weisshaar B, Stabel S, Doerfler W. Arrangement and expression of integrated adenovirus type 12 DNA in the transformed hamster cell line HA12/7: amplification of Ad12 and c-myc DNAs and evidence for hybrid viral-cellular transcripts Virus Research. 13: 113-128. PMID 2773593 DOI: 10.1016/0168-1702(89)90010-5 |
0.474 |
|
1989 |
Hasson TB, Soloway PD, Ornelles DA, Doerfler W, Shenk T. Adenovirus L1 52- and 55-kilodalton proteins are required for assembly of virions Journal of Virology. 63: 3612-3621. PMID 2760976 DOI: 10.1128/Jvi.63.9.3612-3621.1989 |
0.466 |
|
1989 |
Doerfler W, Jessberger R, Lichtenberg U. Recombination between adenovirus DNA and the mammalian genome Current Topics in Microbiology and Immunology. 144: 209-216. PMID 2676362 |
0.437 |
|
1989 |
Müller T, Achten S, Walk RA, Doerfler W. DNA-DNA dot hybridization technique used as DNA determination method in the alkaline elution analysis of DNA damage Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 215: 205-211. PMID 2601730 DOI: 10.1016/0027-5107(89)90185-1 |
0.467 |
|
1989 |
Müller U, Roberts MP, Engel DA, Doerfler W, Shenk T. Induction of transcription factor AP-1 by adenovirus E1A protein and cAMP. Genes & Development. 3: 1991-2002. PMID 2559873 DOI: 10.1101/Gad.3.12A.1991 |
0.456 |
|
1989 |
Jessberger R, Heuss D, Doerfler W. Recombination in hamster cell nuclear extracts between adenovirus type 12 DNA and two hamster preinsertion sequences Embo Journal. 8: 869-878. PMID 2542024 |
0.453 |
|
1989 |
Hermann R, Hoeveler A, Doerfler W. Sequence-specific methylation in a downstream region of the late E2A promoter of adenovirus type 2 DNA prevents protein binding Journal of Molecular Biology. 210: 411-415. PMID 2532258 DOI: 10.1016/0022-2836(89)90340-9 |
0.363 |
|
1989 |
Toth M, Lichtenberg U, Doerfler W. Genomic sequencing reveals a 5-methylcytosine-free domain in active promoters and the spreading of preimposed methylation patterns Proceedings of the National Academy of Sciences of the United States of America. 86: 3728-3732. PMID 2524831 |
0.309 |
|
1989 |
Bartnik E, Doerfler W. Chromatin structure and levels of expression and DNA methylation in the E3 region of chromosomally integrated adenovirus type 12 DNA Bba - Gene Structure and Expression. 1007: 228-232. PMID 2522012 DOI: 10.1016/0167-4781(89)90044-4 |
0.388 |
|
1989 |
Doerfler W. Malignant transformation of cells by DNA viruses: adenovirus DNA integration in the mammalian genome Critical Reviews in Oncogenesis. 1: 211-219. PMID 2488131 |
0.469 |
|
1989 |
Knust B, Bruggemann U, Doerfler W. Reactivation of a methylation-silenced gene in adenovirus-transformed cells by 5-azacytidine or by E1A trans activation Journal of Virology. 63: 3519-3524. PMID 2473219 |
0.374 |
|
1989 |
Doerfler W. DNA methylation, gene regulation and imprinting Journal of Reproductive Immunology. 15: 4. DOI: 10.1016/0165-0378(89)90063-6 |
0.422 |
|
1988 |
Rosahl T, Doerfler W. Predominant association of adenovirus type 12 DNA with human chromosome 1 early in productive infection Virology. 162: 494-497. PMID 3341119 DOI: 10.1016/0042-6822(88)90494-1 |
0.356 |
|
1988 |
Lichtenberg U, Zock C, Doerfler W. Integration of foreign DNA into mammalian genome can be associated with hypomethylation at site of insertion Virus Research. 11: 335-342. PMID 3223064 DOI: 10.1016/0168-1702(88)90006-8 |
0.456 |
|
1988 |
Weisshaar B, Langner KD, Jüttermann R, Müller U, Zock C, Klimkait T, Doerfler W. Reactivation of the methylation-inactivated late E2A promoter of adenovirus type 2 by E1A (13 S) functions Journal of Molecular Biology. 202: 255-270. PMID 2971812 DOI: 10.1016/0022-2836(88)90456-1 |
0.38 |
|
1988 |
Doerfler W, Weisshaar B, Hoeveler A, Knebel D, Müller U, Dobrzański P, Lichtenberg U, Achten S, Hermann R. Promoter inhibition by DNA methylation: a reversible signal Gene. 74: 129-133. PMID 2854801 DOI: 10.1016/0378-1119(88)90268-5 |
0.374 |
|
1988 |
Knebel-Mörsdorf D, Achten S, Langner KD, Rüger R, Fleckenstein B, Doerfler W. Reactivation of the methylation-inhibited late E2A promoter of adenovirus type 2 by a strong enhancer of human cytomegalovirus Virology. 166: 166-174. PMID 2842942 DOI: 10.1016/0042-6822(88)90158-4 |
0.328 |
|
1988 |
Dobrzanski P, Hoeveler A, Doerfler W. Inactivation by sequence-specific methylations of adenovirus promoters in a cell-free transcription system Journal of Virology. 62: 3941-3946. PMID 2459407 |
0.304 |
|
1987 |
Wienhues U, Hosokawa K, Höveler A, Siegmann B, Doerfler W. A novel method for transfection and expression of reconstituted DNA-protein complexes in eukaryotic cells Dna. 6: 81-89. PMID 3829890 |
0.499 |
|
1987 |
Achten S, Doerfler W. Characterization of a member of the highly repeated long interspersed rat DNA family with long open reading frames. Journal of Molecular Biology. 192: 489-502. PMID 3560224 DOI: 10.1016/0022-2836(86)90271-8 |
0.362 |
|
1987 |
Knebel D, Doerfler W. Activation of an insect baculovirus promoter in mammalian cells by adenovirus functions Virus Research. 8: 317-326. PMID 2963453 DOI: 10.1016/0168-1702(87)90004-9 |
0.308 |
|
1987 |
Hoeveler A, Doerfler W. Specific factors binding to the late E2A promoter region of adenovirus type 2 DNA: No apparent effects of 5'-CCGG-3' methylation Dna. 6: 449-460. PMID 2960507 |
0.303 |
|
1987 |
Muller U, Doerfler W. Fixation of the unmethylated or the 5'-CCGG-3' methylated adenovirus late E2A promotor-cat gene construct in the genome of hamster cells: Gene expression and stability of methylation patterns Journal of Virology. 61: 3710-3720. PMID 2824809 |
0.324 |
|
1987 |
Schulz M, Freisem-Rabien U, Jessberger R, Doerfler W. Transcriptional activities of mammalian genomes at sites of recombination with foreign DNA. Journal of Virology. 61: 344-353. DOI: 10.1128/jvi.61.2.344-353.1987 |
0.404 |
|
1986 |
Hübscher U, Pedrali-Noy G, Knust-Kron B, Doerfler W, Spadari S. DNA methyltransferases: activity minigel analysis and determination with DNA covalently bound to a solid matrix. Analytical Biochemistry. 150: 442-8. PMID 4091268 DOI: 10.1016/0003-2697(85)90533-0 |
0.491 |
|
1986 |
Schellner J, Stüber K, Doerfler W. Computer analyses on the structure of junction sites between adenovirus DNA and cellular DNA. Biochimica Et Biophysica Acta. 867: 114-23. PMID 3718989 DOI: 10.1016/0167-4781(86)90071-0 |
0.481 |
|
1986 |
Vogel S, Rosahl T, Doerfler W. Chromosomal localization of integrated adenovirus DNA in productively infected and in transformed mammalian cells. Virology. 152: 159-70. PMID 3716202 DOI: 10.1016/0042-6822(86)90381-8 |
0.345 |
|
1986 |
Langner KD, Weyer U, Doerfler W. Trans effect of the E1 region of adenoviruses on the expression of a prokaryotic gene in mammalian cells: resistance to 5' -CCGG- 3' methylation. Proceedings of the National Academy of Sciences of the United States of America. 83: 1598-1602. PMID 2937060 DOI: 10.1073/pnas.83.6.1598 |
0.401 |
|
1985 |
Arif BM, Tjia ST, Doerfler W. DNA homologies between the genomes of Choristoneura fumiferana and Autographa californica nuclear polyhedrosis viruses. Virus Research. 2: 85-94. PMID 3885612 DOI: 10.1016/0168-1702(85)90062-0 |
0.393 |
|
1985 |
Wienhues U, Doerfler W. Lack of evidence for methylation of parental and newly synthesized adenovirus type 2 DNA in productive infections. Journal of Virology. 56: 320-324. DOI: 10.1128/jvi.56.1.320-324.1985 |
0.324 |
|
1985 |
Klimkait T, Doerfler W. Adenovirus types 2 and 5 functions elicit replication and late expression of adenovirus type 12 DNA in hamster cells. Journal of Virology. 55: 466-474. DOI: 10.1128/jvi.55.2.466-474.1985 |
0.371 |
|
1985 |
Doerfler W. DNA Methylation and Cellular Differentiation.J. Herbert Taylor , M. Alfert The Quarterly Review of Biology. 60: 333-334. DOI: 10.1086/414438 |
0.333 |
|
1985 |
Weyer U, Doerfler W. Species dependence of the major late promoter in adenovirus type 12 DNA. The Embo Journal. 4: 3015-3019. DOI: 10.1002/j.1460-2075.1985.tb04037.x |
0.395 |
|
1985 |
Knebel D, Lübbert H, Doerfler W. The promoter of the late p10 gene in the insect nuclear polyhedrosis virus Autographa californica: activation by viral gene products and sensitivity to DNA methylation. The Embo Journal. 4: 1301-1306. DOI: 10.1002/j.1460-2075.1985.tb03776.x |
0.362 |
|
1985 |
DOERFLER W. ChemInform Abstract: DNA METHYLATION: GENE INACTIVATION BY SEQUENCE-SPECIFIC DNA METHYLATION Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198519363 |
0.468 |
|
1984 |
Doerfler W, Gahlmann R, Stabel S, Deuring R, Lichtenberg U, Schulz M, Eick D, Leisten R. On the mechanism of recombination between adenoviral and cellular DNAs: the structure of junction sites. Current Topics in Microbiology and Immunology. 109: 193-228. PMID 6697766 DOI: 10.1007/978-3-642-69460-8_9 |
0.383 |
|
1984 |
Eick D, Fritz HJ, Doerfler W. Quantitative determination of 5-methylcytosine in DNA by reverse-phase high-performance liquid chromatography. Analytical Biochemistry. 135: 165-71. PMID 6422793 DOI: 10.1016/0003-2697(83)90746-7 |
0.47 |
|
1984 |
Doerfler W. DNA methylation and its functional significance: studies on the adenovirus system. Current Topics in Microbiology and Immunology. 108: 79-98. PMID 6370614 DOI: 10.1007/978-3-642-69370-0_6 |
0.42 |
|
1984 |
Schulz M, Doerfler W. Deletion of cellular DNA at site of viral DNA insertion in the adenovirus type 12-induced mouse tumor CBA-12-1-T. Nucleic Acids Research. 12: 4959-76. PMID 6330692 DOI: 10.1093/nar/12.12.4959 |
0.489 |
|
1984 |
Langner KD, Vardimon L, Renz D, Doerfler W. DNA methylation of three 5' C-C-G-G 3' sites in the promoter and 5' region inactivate the E2a gene of adenovirus type 2. Proceedings of the National Academy of Sciences of the United States of America. 81: 2950-4. PMID 6328479 DOI: 10.1073/pnas.81.10.2950 |
0.381 |
|
1984 |
Deuring R, Doerfler W. Proof of recombination between viral and cellular genomes in human KB cells productively infected by adenovirus type 12: structure of the junction site in a symmetric recombinant (SYREC). Gene. 26: 283-9. PMID 6323266 DOI: 10.1016/0378-1119(83)90198-1 |
0.504 |
|
1984 |
Gahlmann R, Doerfler W. Integration of viral DNA into the genome of the adenovirus type 2-transformed hamster cell line HE5 without loss or alteration of cellular nucleotides. Nucleic Acids Research. 11: 7347-61. PMID 6316259 DOI: 10.1093/nar/11.21.7347 |
0.49 |
|
1984 |
Doerfler W. DNA Methylation: Site-Specific Methylations Cause Gene Inactivation Angewandte Chemie International Edition in English. 23: 919-931. DOI: 10.1002/anie.198409193 |
0.357 |
|
1984 |
Doerfler W. DNA-Methylierung: Geninaktivierung durch sequenzspezifische DNA-Methylierungen Angewandte Chemie. 96: 917-929. DOI: 10.1002/ange.19840961204 |
0.497 |
|
1983 |
Via ST, zu Altenschildesche GM, Doerfler W. Autographa californica nuclear polyhedrosis virus (AcNPV) DNA does not persist in mass cultures of mammalian cells Virology. 125: 107-117. PMID 6402854 DOI: 10.1016/0042-6822(83)90067-3 |
0.445 |
|
1983 |
Doerfler W. DNA methylation and gene activity. Annual Review of Biochemistry. 52: 93-124. PMID 6311083 DOI: 10.1146/annurev.bi.52.070183.000521 |
0.435 |
|
1983 |
Doerfler W, Kruczek I, Eick D, Vardimon L, Kron B. DNA methylation and gene activity: the adenovirus system as a model. Cold Spring Harbor Symposia On Quantitative Biology. 593-603. PMID 6305579 DOI: 10.1101/SQB.1983.047.01.070 |
0.423 |
|
1983 |
Doerfler W. Uptake, fixation, and expression of foreign DNA in mammalian cells: the organization of integrated adenovirus DNA sequences. Current Topics in Microbiology and Immunology. 101: 127-94. PMID 6303701 DOI: 10.1007/978-3-642-68654-2_6 |
0.461 |
|
1983 |
Stabel S, Doerfler W. Nucleotide sequence at the site of junction between adenovirus type 12 DNA and repetitive hamster cell DNA in transformed cell line CLAC1. Nucleic Acids Research. 10: 8007-23. PMID 6298706 DOI: 10.1093/nar/10.24.8007 |
0.491 |
|
1983 |
Kuhlmann I, Doerfler W. Loss of viral genomes from hamster tumor cells and nonrandom alterations in patterns of methylation of integrated adenovirus type 12 DNA. Journal of Virology. 47: 631-636. DOI: 10.1128/jvi.47.3.631-636.1983 |
0.354 |
|
1983 |
Eick D, Kemper B, Doerfler W. Excision of amplified viral DNA at palindromic sequences from the adenovirus type 12-transformed hamster cell line T637. The Embo Journal. 2: 1981-1986. DOI: 10.1002/j.1460-2075.1983.tb01688.x |
0.364 |
|
1982 |
Vardimon L, Kressmann A, Cedar H, Maechler M, Doerfler W. Expression of a cloned adenovirus gene is inhibited by in vitro methylation. Proceedings of the National Academy of Sciences of the United States of America. 79: 1073-7. PMID 6951163 DOI: 10.1073/pnas.79.4.1073 |
0.473 |
|
1982 |
Lübbert H, Kruczek I, Tjia S, Doerfler W. The cloned EcoRI fragments of Autographa californica nuclear polyhedrosis virus DNA. Gene. 16: 343-5. PMID 6282701 DOI: 10.1016/0378-1119(81)90092-5 |
0.434 |
|
1982 |
Kuhlmann I, Doerfler W. Shifts in the extent and patterns of DNA methylation upon explanation and subcultivation of adenovirus type 12-induced hamster tumor cells. Virology. 118: 169-80. PMID 6281967 DOI: 10.1016/0042-6822(82)90330-0 |
0.348 |
|
1982 |
Doerfler W. DNA methylation--a regulatory signal in eukaryotic gene expression. The Journal of General Virology. 57: 1-20. PMID 6275010 DOI: 10.1099/0022-1317-57-1-1 |
0.381 |
|
1982 |
Vogel S, Brötz M, Kruczek I, Neumann R, Eick D, Winterhoff U, Doerfler W. Cloned fragments of human adenovirus type-12 DNA. Gene. 15: 273-8. PMID 6271646 DOI: 10.1016/0378-1119(81)90136-0 |
0.31 |
|
1982 |
Eick D, Doerfler W. Integrated adenovirus type 12 DNA in the transformed hamster cell line T637: sequence arrangements at the termini of viral DNA and mode of amplification. Journal of Virology. 42: 317-321. DOI: 10.1128/jvi.42.1.317-321.1982 |
0.435 |
|
1982 |
Gahlmann R, Leisten R, Vardimon L, Doerfler W. Patch homologies and the integration of adenovirus DNA in mammalian cells. The Embo Journal. 1: 1101-1104. DOI: 10.1002/j.1460-2075.1982.tb01303.x |
0.456 |
|
1982 |
Starzinski-Powitz A, Schulz M, Esche H, Mukai N, Doerfler W. The adenovirus type 12 - mouse cell system: permissivity and analysis of integration patterns of viral DNA in tumor cells. The Embo Journal. 1: 493-497. DOI: 10.1002/j.1460-2075.1982.tb01196.x |
0.34 |
|
1981 |
Deuring R, Winterhoff U, Tamanoi F, Stabel S, Doerfler W. Site of linkage between adenovirus type 12 and cell DNAs in hamster tumour line CLAC3. Nature. 293: 81-4. PMID 6455603 DOI: 10.1038/293081a0 |
0.363 |
|
1981 |
Vardimon L, Doerfler W. Patterns of integration of viral DNA in adenovirus type 2-transformed hamster cells. Journal of Molecular Biology. 147: 227-46. PMID 6270338 DOI: 10.1016/0022-2836(81)90439-3 |
0.387 |
|
1981 |
Deuring R, Klotz G, Doerfler W. An unusual symmetric recombinant between adenovirus type 12 DNA and human cell DNA. Proceedings of the National Academy of Sciences of the United States of America. 78: 3142-6. PMID 6265937 DOI: 10.1073/pnas.78.5.3142 |
0.502 |
|
1981 |
Sutter D, Doerfler W. Methylation of integrated viral DNA sequences in hamster cells transformed by adenovirus 12. Cold Spring Harbor Symposia On Quantitative Biology. 565-8. PMID 6253157 DOI: 10.1101/SQB.1980.044.01.058 |
0.455 |
|
1981 |
Doerfler W, Stabel S, Ibelgaufts H, Sutter D, Neumann R, Groneberg J, Scheidtmann KH, Deuring R, Winterhoff U. Selectivity in integration sites of adenoviral DNA. Cold Spring Harbor Symposia On Quantitative Biology. 551-64. PMID 6253156 DOI: 10.1101/SQB.1980.044.01.057 |
0.371 |
|
1981 |
Vardimon L, Neumann R, Kuhlmann I, Sutter D, Doerfler W. DNA methylation and viral gene expression in adenovirus-transformed and -infected cells. Nucleic Acids Research. 8: 2461-73. PMID 6160461 DOI: 10.1093/nar/8.11.2461 |
0.402 |
|
1981 |
Schirm S, Doerfler W. Expression of Viral DNA in Adenovirus Type 12-Transformed Cells, in Tumor Cells, and in Revertants Journal of Virology. 39: 694-702. DOI: 10.1128/jvi.39.3.694-702.1981 |
0.329 |
|
1981 |
Neumann R, Doerfler W. Integration of adenovirus type 2 DNA at a limited number of cellular sites in productively infected cells. Journal of Virology. 37: 887-892. DOI: 10.1128/jvi.37.3.887-892.1981 |
0.345 |
|
1980 |
Sutter D, Doerfler W. Methylation of integrated adenovirus type 12 DNA sequences in transformed cells is inversely correlated with viral gene expression. Proceedings of the National Academy of Sciences of the United States of America. 77: 253-6. PMID 6244548 DOI: 10.1073/pnas.77.1.253 |
0.428 |
|
1980 |
Stabel S, Doerfler W, Friis RR. Integration Sites of Adenovirus Type 12 DNA in Transformed Hamster Cells and Hamster Tumor Cells Journal of Virology. 36: 22-40. DOI: 10.1128/jvi.36.1.22-40.1980 |
0.317 |
|
1980 |
Carstens EB, Tjia ST, Doerfler W. Infectious DNA from Autographa californica nuclear polyhedrosis virus Virology. 101: 311-314. DOI: 10.1016/0042-6822(80)90511-5 |
0.479 |
|
1979 |
Cairns E, Doerfler W, Schweiger HG. Expression of a DNA animal virus genome in a plant cell. Febs Letters. 96: 295-7. PMID 729800 DOI: 10.1016/0014-5793(78)80421-9 |
0.322 |
|
1979 |
Schick J, Doerfler W. High molecular weight virus DNA in KB cells infected with ts mutants of adenovirus type 2 under permissive and non-permissive conditions. The Journal of General Virology. 43: 217-22. PMID 479842 DOI: 10.1099/0022-1317-43-1-217 |
0.467 |
|
1979 |
Padmanabhan R, Stabel S, Winterhoff U, Doerfler W. Specificity and mode of cleavage of the pH 4.0 endonuclease from adenovirus type 2 - infected KB cells. Nucleic Acids Research. 6: 3161-76. PMID 40209 DOI: 10.1093/nar/6.9.3161 |
0.378 |
|
1979 |
Tjia ST, Carstens EB, Doerfler W. Infection of Spodoptera frugiperda cells with Autographa californica nuclear polyhedrosis virus. II. The viral DNA and the kinetics of its replication Virology. 99: 399-409. DOI: 10.1016/0042-6822(79)90018-7 |
0.522 |
|
1978 |
Sutter D, Westphal M, Doerfler W. Patterns of integration of viral DNA sequences in the genomes of adenovirus type 12-transformed hamster cells. Cell. 14: 569-85. PMID 688383 DOI: 10.1016/0092-8674(78)90243-X |
0.462 |
|
1978 |
Fanning E, Schick J, Doerfler W. Studies on the occurrence of high molecular weight adenovirus type 2 DNA in productively infected cells Virology. 88: 186-190. PMID 676077 DOI: 10.1016/0042-6822(78)90123-X |
0.659 |
|
1978 |
Brötz M, Doerfler W, Tamm I. Inhibition of adenovirus replication by 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole. Virology. 86: 516-29. PMID 664245 DOI: 10.1016/0042-6822(78)90090-9 |
0.427 |
|
1978 |
Baczko K, Neumann R, Doerfler W. Intracellular forms of adenovirus DNA. VII. Excision of viral sequences from cellular DNA in adenovirus type 2-infected KB cells. Virology. 85: 557-67. PMID 664216 DOI: 10.1016/0042-6822(78)90461-0 |
0.497 |
|
1978 |
Schick J, Doerfler W. Integration of adenovirus type 2 DNA in productively infected cells: results of sequential hybridization experiments. The Journal of General Virology. 39: 365-70. PMID 650178 DOI: 10.1099/0022-1317-39-2-365 |
0.489 |
|
1977 |
Gunthert U, Schweiger M, Stupp M, Doerfler W. DNA methylation in adenovirus, adenovirus-transformed cells, and host cells. Proceedings of the National Academy of Sciences of the United States of America. 73: 3923-7. PMID 1069277 DOI: 10.1073/pnas.73.11.3923 |
0.46 |
|
1977 |
Ogier G, Chardonnet Y, Doerfler W. The fate of type 7 adenovirions in lysosomes of HeLa cells. Virology. 77: 67-77. PMID 841871 DOI: 10.1016/0042-6822(77)90406-8 |
0.399 |
|
1977 |
Groneberg J, Chardonnet Y, Doerfler W. Integrated viral sequences in adenovirus type 12-transformed hamster cells. Cell. 10: 101-11. PMID 837440 DOI: 10.1016/0092-8674(77)90144-1 |
0.442 |
|
1977 |
Tjia S, Fanning E, Schick J, Doerfler W. Incomplete particles of adenovirus type 2 III. Viral and cellular DNA sequences in incomplete particles Virology. 76: 365-379. PMID 835233 DOI: 10.1016/0042-6822(77)90309-9 |
0.625 |
|
1976 |
Schick J, Baczko K, Fanning E, Groneberg J, Burger H, Doerfler W. Intracellular forms of adenovirus DNA: integrated form of adenovirus DNA appears early in productive infection Proceedings of the National Academy of Sciences of the United States of America. 73: 1043-1047. PMID 1063388 DOI: 10.1073/pnas.73.4.1043 |
0.676 |
|
1976 |
Doerfler W. Integration of viral DNA into the host genome. Current Topics in Microbiology and Immunology. 71: 1-78. PMID 172288 DOI: 10.1007/978-3-642-66193-8_1 |
0.372 |
|
1975 |
Groneberg J, Brown DT, Doerfler W. Uptake and fate of the DNA of adenovirus type 2 in KB cells Virology. 64: 115-131. PMID 1114705 DOI: 10.1016/0042-6822(75)90084-7 |
0.525 |
|
1975 |
Doerfler W, Burger H, Ortin J, Fanning E, Brown DT, Mestphal M, Winterhoff U, Weiser B, Schick J. Integration of adenovirus DNA into the cellular genome. Cold Spring Harbor Symposia On Quantitative Biology. 505-21. PMID 1057478 DOI: 10.1101/Sqb.1974.039.01.063 |
0.607 |
|
1974 |
Burlingham BT, Brown DT, Doerfler W. Incomplete particles of adenovirus. I. Characteristics of the DNA associated with incomplete adenovirions of types 2 and 12. Virology. 60: 419-30. PMID 4844422 DOI: 10.1016/0042-6822(74)90336-5 |
0.355 |
|
1974 |
Burger H, Doerfler W. Intracellular Forms of Adenovirus DNA III. Integration of the DNA of Adenovirus Type 2 into Host DNA in Productively Infected Cells Journal of Virology. 13: 975-992. DOI: 10.1128/jvi.13.5.975-992.1974 |
0.485 |
|
1973 |
Doerfler W, Lundholm U, Rensing U, Philipson L. Intracellular Forms of Adenovirus DNA II. Isolation in Dye-Buoyant Density Gradients of a DNA-RNA Complex from KB Cells Infected with Adenovirus Type 2 Journal of Virology. 12: 793-807. DOI: 10.1128/Jvi.12.4.793-807.1973 |
0.321 |
|
1971 |
Burlingham BT, Doerfler W, Pettersson U, Philipson L. Adenovirus endonuclease: association with the penton of adenovirus type 2. Journal of Molecular Biology. 60: 45-64. PMID 5572103 DOI: 10.1016/0022-2836(71)90446-3 |
0.456 |
|
1970 |
Doerfler W, Kleinschmidt AK. Denaturation pattern of the DNA of adenovirus type 2 as determined by electron microscopy. Journal of Molecular Biology. 50: 579-93. PMID 5477340 DOI: 10.1016/0022-2836(70)90086-0 |
0.319 |
|
1970 |
Doerfler W, Lundholm U. Absence of replication of the DNA of adenovirus type 12 in BHK21 cells. Virology. 40: 754-7. PMID 5461848 DOI: 10.1016/0042-6822(70)90222-9 |
0.463 |
|
1969 |
Doerfler W. The fate of the DNA of adenovirus type 12 in baby hamster kidney cells. Proceedings of the National Academy of Sciences of the United States of America. 60: 636-43. PMID 5248820 DOI: 10.1073/pnas.60.2.636 |
0.411 |
|
1968 |
Doerfler W, Hogness DS. Gene orientation in bacteriophage lambda as determined from the genetic activities of heteroduplex DNA formed in vitro. Journal of Molecular Biology. 33: 661-78. PMID 5700418 DOI: 10.1016/0022-2836(68)90312-4 |
0.685 |
|
1968 |
Doerfler W, Hogness DS. The strands of DNA from lambda and related bacteriophages: isolation and characterization. Journal of Molecular Biology. 33: 635-59. PMID 5700417 DOI: 10.1016/0022-2836(68)90311-2 |
0.695 |
|
1966 |
Hogness DS, Doerfler W, Egan JB, Black LW. The position and orientation of genes in lambda and lambda dg DNA. Cold Spring Harbor Symposia On Quantitative Biology. 31: 129-38. PMID 4866370 DOI: 10.1101/Sqb.1966.031.01.020 |
0.674 |
|
1965 |
Doerfler W, Hogness DS. Separation of the strands of poly d-TG: AC in alkaline CsCl. Journal of Molecular Biology. 14: 237-40. PMID 5883915 DOI: 10.1016/S0022-2836(65)80243-1 |
0.559 |
|
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