Hank Michael Petrassi - Publications

Affiliations: 
2001 Scripps Research Institute, La Jolla, La Jolla, CA, United States 

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Orr AL, Vargas L, Turk CN, Baaten JE, Matzen JT, Dardov VJ, Attle SJ, Li J, Quackenbush DC, Goncalves RL, Perevoshchikova IV, Petrassi HM, Meeusen SL, Ainscow EK, Brand MD. Suppressors of superoxide production from mitochondrial complex III. Nature Chemical Biology. 11: 834-6. PMID 26368590 DOI: 10.1038/nchembio.1910  0.76
2014 Rooney L, Vidal A, D'Souza AM, Devereux N, Masick B, Boissel V, West R, Head V, Stringer R, Lao J, Petrus MJ, Patapoutian A, Nash M, Stoakley N, Panesar M, ... ... Petrassi HM, et al. Discovery, optimization, and biological evaluation of 5-(2-(trifluoromethyl)phenyl)indazoles as a novel class of transient receptor potential A1 (TRPA1) antagonists. Journal of Medicinal Chemistry. 57: 5129-40. PMID 24884675 DOI: 10.1021/jm401986p  0.76
2010 Liu B, Lee Y, Zou J, Petrassi HM, Joseph RW, Chao W, Michelotti EL, Bukhtiyarova M, Springman EB, Dorsey BD. Discovery and SAR of a series of 4,6-diamino-1,3,5-triazin-2-ol as novel non-nucleoside reverse transcriptase inhibitors of HIV-1. Bioorganic & Medicinal Chemistry Letters. 20: 6592-6. PMID 20888224 DOI: 10.1016/j.bmcl.2010.09.034  0.76
2009 Li J, Petrassi HM, Tumanut C, Masick BT, Trussell C, Harris JL. Substrate optimization for monitoring cathepsin C activity in live cells. Bioorganic & Medicinal Chemistry. 17: 1064-70. PMID 18313933 DOI: 10.1016/j.bmc.2008.02.002  0.76
2008 Tully DC, Vidal A, Chatterjee AK, Williams JA, Roberts MJ, Petrassi HM, Spraggon G, Bursulaya B, Pacoma R, Shipway A, Schumacher AM, Danahay H, Harris JL. Discovery of inhibitors of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design. Bioorganic & Medicinal Chemistry Letters. 18: 5895-9. PMID 18752942 DOI: 10.1016/j.bmcl.2008.08.029  0.76
2005 Petrassi HM, Williams JA, Li J, Tumanut C, Ek J, Nakai T, Masick B, Backes BJ, Harris JL. A strategy to profile prime and non-prime proteolytic substrate specificity. Bioorganic & Medicinal Chemistry Letters. 15: 3162-6. PMID 15878267 DOI: 10.1016/j.bmcl.2005.04.019  0.76
2005 Petrassi HM, Johnson SM, Purkey HE, Chiang KP, Walkup T, Jiang X, Powers ET, Kelly JW. Potent and selective structure-based dibenzofuran inhibitors of transthyretin amyloidogenesis: kinetic stabilization of the native state. Journal of the American Chemical Society. 127: 6662-71. PMID 15869287 DOI: 10.1021/ja044351f  0.76
2005 Johnson SM, Petrassi HM, Palaninathan SK, Mohamedmohaideen NN, Purkey HE, Nichols C, Chiang KP, Walkup T, Sacchettini JC, Sharpless KB, Kelly JW. Bisaryloxime ethers as potent inhibitors of transthyretin amyloid fibril formation. Journal of Medicinal Chemistry. 48: 1576-87. PMID 15743199 DOI: 10.1021/jm049274d  0.76
2002 McCammon MG, Scott DJ, Keetch CA, Greene LH, Purkey HE, Petrassi HM, Kelly JW, Robinson CV. Screening transthyretin amyloid fibril inhibitors: characterization of novel multiprotein, multiligand complexes by mass spectrometry. Structure (London, England : 1993). 10: 851-63. PMID 12057199 DOI: 10.1016/S0969-2126(02)00771-2  0.76
2002 Oza VB, Smith C, Raman P, Koepf EK, Lashuel HA, Petrassi HM, Chiang KP, Powers ET, Sachettinni J, Kelly JW. Synthesis, structure, and activity of diclofenac analogues as transthyretin amyloid fibril formation inhibitors. Journal of Medicinal Chemistry. 45: 321-32. PMID 11784137 DOI: 10.1021/jm010257n  0.76
2001 Jiang X, Smith CS, Petrassi HM, Hammarström P, White JT, Sacchettini JC, Kelly JW. An engineered transthyretin monomer that is nonamyloidogenic, unless it is partially denatured. Biochemistry. 40: 11442-52. PMID 11560492 DOI: 10.1021/bi011194d  0.76
2001 Petrassi HM, Sharpless KB, Kelly JW. The copper-mediated cross-coupling of phenylboronic acids and N-hydroxyphthalimide at room temperature: synthesis of aryloxyamines. Organic Letters. 3: 139-42. PMID 11429858 DOI: 10.1021/ol0003533  0.76
2000 Klabunde T, Petrassi HM, Oza VB, Raman P, Kelly JW, Sacchettini JC. Rational design of potent human transthyretin amyloid disease inhibitors. Nature Structural Biology. 7: 312-21. PMID 10742177 DOI: 10.1038/74082  0.76
2000 Petrassi HM, Klabunde T, Sacchettini J, Kelly JW. Structure-based design of N-phenyl phenoxazine transthyretin amyloid fibril inhibitors Journal of the American Chemical Society. 122: 2178-2192. DOI: 10.1021/ja993309v  0.76
1999 Koepf EK, Petrassi HM, Ratnaswamy G, Huff ME, Sudol M, Kelly JW. Characterization of the structure and function of W --> F WW domain variants: identification of a natively unfolded protein that folds upon ligand binding. Biochemistry. 38: 14338-51. PMID 10572009 DOI: 10.1021/bi991105l  0.76
1999 Koepf EK, Petrassi HM, Sudol M, Kelly JW. WW: An isolated three-stranded antiparallel beta-sheet domain that unfolds and refolds reversibly; evidence for a structured hydrophobic cluster in urea and GdnHCl and a disordered thermal unfolded state. Protein Science : a Publication of the Protein Society. 8: 841-53. PMID 10211830 DOI: 10.1110/ps.8.4.841  0.76
1999 Oza VB, Petrassi HM, Purkey HE, Kelly JW. Synthesis and evaluation of anthranilic acid-based transthyretin amyloid fibril inhibitors. Bioorganic & Medicinal Chemistry Letters. 9: 1-6. PMID 9990446 DOI: 10.1016/S0960-894X(98)00696-9  0.76
1999 McGrath JL, Kabza KG, Gestwicki JE, Petrassi HM. Comparison of thermal and microwave energy: Model biological systems and energy input Proceedings of Spie - the International Society For Optical Engineering. 3854: 126-134.  0.76
1996 Kabza KG, Gestwicki JE, McGrath JL, Petrassi HM. Effect of microwave radiation on copper(II) 2,2′-bipyridyl-mediated hydrolysis of bis(p-nitrophenyl) phosphodiester and enzymatic hydrolysis of carbohydrates Journal of Organic Chemistry. 61: 9599-9602.  0.76
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