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Jean-Christophe Rochet - Publications

Purdue University, West Lafayette, IN, United States 
Parkinson’s disease, protein aggregation

75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Tambe MA, de Rus Jacquet A, Strathearn KE, Hensel JA, Colón BD, Chandran A, Yousef GG, Grace MH, Ferruzzi MG, Wu Q, Simon JE, Lila MA, Rochet JC. Protective Effects of Polyphenol-Rich Extracts against Neurotoxicity Elicited by Paraquat or Rotenone in Cellular Models of Parkinson's Disease. Antioxidants (Basel, Switzerland). 12. PMID 37508001 DOI: 10.3390/antiox12071463  0.783
2023 Ramirez E, Ganegamage SK, Elbatrawy AA, Alnakhala H, Shimanaka K, Tripathi A, Min S, Rochet JC, Dettmer U, Fortin JS. 5-Nitro-1,2-benzothiazol-3-amine and -Ethyl-1-[(ethylcarbamoyl)(5-nitro-1,2-benzothiazol-3-yl)amino]formamide Modulate α-Synuclein and Tau Aggregation. Acs Omega. 8: 20102-20115. PMID 37305264 DOI: 10.1021/acsomega.3c02668  0.304
2023 Tambe MA, de Rus Jacquet A, Strathearn KE, Yousef GG, Grace MH, Ferruzzi MG, Wu Q, Simon JE, Lila MA, Rochet JC. Protective effects of polyphenol-rich extracts against neurotoxicity elicited by paraquat or rotenone in cellular models of Parkinson's disease. Biorxiv : the Preprint Server For Biology. PMID 37163110 DOI: 10.1101/2023.04.26.538474  0.783
2021 de Rus Jacquet A, Ambaw A, Tambe MA, Ma SY, Timmers M, Grace MH, Wu QL, Simon JE, McCabe GP, Lila MA, Shi R, Rochet JC. Neuroprotective mechanisms of red clover and soy isoflavones in Parkinson's disease models. Food & Function. PMID 34751296 DOI: 10.1039/d1fo00007a  0.369
2020 Landeck N, Strathearn KE, Ysselstein D, Buck K, Dutta S, Banerjee S, Lv Z, Hulleman JD, Hindupur J, Lin LK, Padalkar S, Stanciu LA, Lyubchenko YL, Kirik D, Rochet JC. Two C-terminal sequence variations determine differential neurotoxicity between human and mouse α-synuclein. Molecular Neurodegeneration. 15: 49. PMID 32900375 DOI: 10.1186/S13024-020-00380-W  0.793
2020 Solti K, Kuan WL, Fórizs B, Kustos G, Mihály J, Varga Z, Herberth B, Moravcsik É, Kiss R, Kárpáti M, Mikes A, Zhao Y, Imre T, Rochet JC, Aigbirhio F, et al. Corrigendum to "DJ-1 can form β-sheet structured aggregates that co-localize with pathological amyloid deposits". Neurobiology of Disease 134 (2020) 104629. Neurobiology of Disease. 104971. PMID 32576487 DOI: 10.1016/J.Nbd.2020.104971  0.3
2020 Bentz BZ, Mahalingam SM, Ysselstein D, Montenegro PC, Cannon JR, Rochet JC, Low PS, Webb KJ. Localization of fluorescent targets in deep tissue with expanded beam illumination for studies of cancer and the brain. Ieee Transactions On Medical Imaging. PMID 32031935 DOI: 10.1109/Tmi.2020.2972200  0.503
2019 Tóth G, Neumann T, Berthet A, Masliah E, Spencer B, Tao J, Jobling MF, Gardai SJ, Bertoncini CW, Cremades N, Bova M, Ballaron S, Chen XH, Mao W, Nguyen P, ... ... Rochet JC, et al. Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein Protect Against Diverse α-Synuclein Mediated Dysfunctions. Scientific Reports. 9: 16947. PMID 31740740 DOI: 10.1038/S41598-019-52598-4  0.353
2019 Solti K, Kuan WL, Fórizs B, Kustos G, Judith M, Varga Z, Herberth B, Moravcsik É, Kiss R, Kárpáti M, Mikes A, Zhao Y, Imre T, Rochet JC, Aigbirhio F, et al. DJ-1 can form β-sheet structured aggregates that co-localize with pathological amyloid deposits. Neurobiology of Disease. 104629. PMID 31669752 DOI: 10.1016/j.nbd.2019.104629  0.339
2019 Lawana V, Um SY, Rochet JC, Turesky RJ, Shannahan JH, Cannon JR. Neuromelanin modulates heterocyclic aromatic amine-induced dopaminergic neurotoxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 31562763 DOI: 10.1093/Toxsci/Kfz210  0.612
2019 Lv Z, Hashemi M, Banerjee S, Zagorski K, Rochet JC, Lyubchenko YL. Assembly of α-synuclein aggregates on phospholipid bilayers. Biochimica Et Biophysica Acta. Proteins and Proteomics. PMID 31226488 DOI: 10.1016/J.Bbapap.2019.06.006  0.368
2019 Sanyal A, Dutta S, Camara A, Chandran A, Koller A, Watson BG, Sengupta R, Ysselstein D, Montenegro P, Cannon J, Rochet JC, Mattoo S. Alpha-Synuclein Is a Target of Fic-Mediated Adenylylation/AMPylation: Possible Implications for Parkinson's Disease. Journal of Molecular Biology. PMID 31034889 DOI: 10.1016/J.Jmb.2019.04.026  0.677
2018 Ambaw A, Zheng L, Tambe MA, Strathearn KE, Acosta G, Hubers SA, Liu F, Herr SA, Tang J, Truong A, Walls E, Pond A, Rochet JC, Shi R. Acrolein-mediated neuronal cell death and alpha-synuclein aggregation: Implications for Parkinson's disease. Molecular and Cellular Neurosciences. 88: 70-82. PMID 29414104 DOI: 10.1016/J.Mcn.2018.01.006  0.818
2018 Cruz-Hernandez A, Agim ZS, Montenegro PC, McCabe GP, Rochet JC, Cannon JR. Selective dopaminergic neurotoxicity of three heterocyclic amine subclasses in primary rat midbrain neurons. Neurotoxicology. PMID 29408373 DOI: 10.1016/J.Neuro.2018.01.009  0.606
2017 Collier TJ, Srivastava KR, Justman C, Grammatopoulous T, Hutter-Paier B, Prokesch M, Havas D, Rochet JC, Liu F, Jock K, de Oliveira P, Stirtz GL, Dettmer U, Sortwell CE, Feany MB, et al. Nortriptyline inhibits aggregation and neurotoxicity of alpha-synuclein by enhancing reconfiguration of the monomeric form. Neurobiology of Disease. PMID 28711409 DOI: 10.1016/J.Nbd.2017.07.007  0.305
2017 de Rus Jacquet A, Timmers M, Ma SY, Thieme A, McCabe GP, Vest JH, Lila MA, Rochet JC. Lumbee traditional medicine: Neuroprotective activities of medicinal plants used to treat Parkinson's disease-related symptoms. Journal of Ethnopharmacology. PMID 28214539 DOI: 10.1016/J.Jep.2017.02.021  0.368
2017 Ysselstein D, Dehay B, Costantino IM, McCabe GP, Frosch MP, George JM, Bezard E, Rochet JC. Endosulfine-alpha inhibits membrane-induced α-synuclein aggregation and protects against α-synuclein neurotoxicity. Acta Neuropathologica Communications. 5: 3. PMID 28069058 DOI: 10.1186/S40478-016-0403-7  0.431
2017 Banerjee S, Hashemi M, Lv Z, Maity S, Rochet J, Lyubchenko Y. Aggregation of Amyloid Proteins at the Surface-Liquid Interface Biophysical Journal. 112: 365a. DOI: 10.1016/J.Bpj.2016.11.1977  0.366
2016 Agim Z, Jacquet A, Rochet J, Cannon J. Mechanism of PHIP-induced dopaminergic neurotoxicicty in primary midbrain cultures Toxicology Letters. 259: S198-S199. DOI: 10.1016/J.Toxlet.2016.07.474  0.477
2016 Lv Z, Krasnoslobodtsev AV, Zhang Y, Ysselstein D, Rochet J, Blanchard SC, Lyubchenko YL. Effect of Acidic pH on the Stability of Alpha-Synuclein Dimers Biophysical Journal. 110: 552a. DOI: 10.1016/J.Bpj.2015.11.2952  0.365
2015 Bates CA, Fu S, Ysselstein D, Rochet JC, Zheng W. Expression and Transport of α-Synuclein at the Blood-Cerebrospinal Fluid Barrier and Effects of Manganese Exposure. Admet & Dmpk. 3: 15-33. PMID 26640596 DOI: 10.5599/Admet.3.1.159  0.312
2015 Tsai CJ, Aslam K, Drendel HM, Asiago JM, Goode KM, Paul LN, Rochet JC, Hazbun TR. Hsp31 Is a Stress Response Chaperone That Intervenes in the Protein Misfolding Process. The Journal of Biological Chemistry. 290: 24816-34. PMID 26306045 DOI: 10.1074/Jbc.M115.678367  0.778
2015 Ysselstein D, Joshi M, Mishra V, Griggs AM, Asiago JM, McCabe GP, Stanciu LA, Post CB, Rochet JC. Effects of impaired membrane interactions on α-synuclein aggregation and neurotoxicity. Neurobiology of Disease. 79: 150-63. PMID 25931201 DOI: 10.1016/J.Nbd.2015.04.007  0.807
2015 Tsai CJ, Aslam K, Drendel HM, Asiago JM, Goode KM, Paul LN, Rochet JC, Hazbun TR. Hsp31 is a stress response chaperone that intervenes in the protein misfolding process Journal of Biological Chemistry. 290: 24816-24834. DOI: 10.1074/jbc.M115.678367  0.757
2015 Lv Z, Krasnoslobodtsev AV, Zhang Y, Ysselstein D, Rochet J, Blanchard S, Lyubchenko YL. Single Molecule Fluorescence Assay of Alpha Synuclein Dimerization Biophysical Journal. 108: 63a. DOI: 10.1016/J.Bpj.2014.11.378  0.31
2014 Griggs AM, Agim ZS, Mishra VR, Tambe MA, Director-Myska AE, Turteltaub KW, McCabe GP, Rochet JC, Cannon JR. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is selectively toxic to primary dopaminergic neurons in vitro. Toxicological Sciences : An Official Journal of the Society of Toxicology. 140: 179-89. PMID 24718704 DOI: 10.1093/Toxsci/Kfu060  0.616
2014 de Rus Jacquet A, Subedi R, Ghimire SK, Rochet JC. Nepalese traditional medicine and symptoms related to Parkinson's disease and other disorders: Patterns of the usage of plant resources along the Himalayan altitudinal range. Journal of Ethnopharmacology. 153: 178-89. PMID 24556225 DOI: 10.1016/J.Jep.2014.02.016  0.363
2014 Tóth G, Gardai SJ, Zago W, Bertoncini CW, Cremades N, Roy SL, Tambe MA, Rochet JC, Galvagnion C, Skibinski G, Finkbeiner S, Bova M, Regnstrom K, Chiou SS, Johnston J, et al. Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease. Plos One. 9: e87133. PMID 24551051 DOI: 10.1371/Journal.Pone.0087133  0.425
2014 Strathearn KE, Yousef GG, Grace MH, Roy SL, Tambe MA, Ferruzzi MG, Wu QL, Simon JE, Lila MA, Rochet JC. Neuroprotective effects of anthocyanin- and proanthocyanidin-rich extracts in cellular models of Parkinson׳s disease. Brain Research. 1555: 60-77. PMID 24502982 DOI: 10.1016/J.Brainres.2014.01.047  0.775
2014 Kurylowicz M, Vanderlee G, Ysselstein D, Walsh P, Yau J, Sharpe S, Rochet J, Yip CM. Combinatorial Polarized TIRF-AFM Study of Membrane Reorganization by Alpha-Synuclein and Human Prion Protein Biophysical Journal. 106: 302a. DOI: 10.1016/J.Bpj.2013.11.1755  0.354
2013 Tardiff DF, Jui NT, Khurana V, Tambe MA, Thompson ML, Chung CY, Kamadurai HB, Kim HT, Lancaster AK, Caldwell KA, Caldwell GA, Rochet JC, Buchwald SL, Lindquist S. Yeast reveal a "druggable" Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neurons. Science (New York, N.Y.). 342: 979-83. PMID 24158909 DOI: 10.1126/Science.1245321  0.389
2013 Krasnoslobodtsev AV, Volkov IL, Asiago JM, Hindupur J, Rochet JC, Lyubchenko YL. α-Synuclein misfolding assessed with single molecule AFM force spectroscopy: effect of pathogenic mutations. Biochemistry. 52: 7377-86. PMID 24066883 DOI: 10.1021/Bi401037Z  0.805
2013 Zhang H, Griggs A, Rochet JC, Stanciu LA. In vitro study of α-synuclein protofibrils by cryo-EM suggests a Cu(2+)-dependent aggregation pathway. Biophysical Journal. 104: 2706-13. PMID 23790379 DOI: 10.1016/J.Bpj.2013.04.050  0.451
2012 Krasnoslobodtsev AV, Peng J, Asiago JM, Hindupur J, Rochet JC, Lyubchenko YL. Effect of spermidine on misfolding and interactions of alpha-synuclein. Plos One. 7: e38099. PMID 22662273 DOI: 10.1371/Journal.Pone.0038099  0.796
2012 Rochet JC, Hay BA, Guo M. Molecular insights into Parkinson's disease. Progress in Molecular Biology and Translational Science. 107: 125-88. PMID 22482450 DOI: 10.1016/B978-0-12-385883-2.00011-4  0.449
2012 Madian AG, Hindupur J, Hulleman JD, Diaz-Maldonado N, Mishra VR, Guigard E, Kay CM, Rochet JC, Regnier FE. Effect of single amino acid substitution on oxidative modifications of the Parkinson's disease-related protein, DJ-1. Molecular & Cellular Proteomics : McP. 11: M111.010892. PMID 22104028 DOI: 10.1074/Mcp.M111.010892  0.756
2011 Pandey AP, Haque F, Rochet JC, Hovis JS. α-Synuclein-induced tubule formation in lipid bilayers. The Journal of Physical Chemistry. B. 115: 5886-93. PMID 21520980 DOI: 10.1021/Jp1121917  0.406
2011 Cullen V, Sardi SP, Ng J, Xu YH, Sun Y, Tomlinson JJ, Kolodziej P, Kahn I, Saftig P, Woulfe J, Rochet JC, Glicksman MA, Cheng SH, Grabowski GA, Shihabuddin LS, et al. Acid β-glucosidase mutants linked to Gaucher disease, Parkinson disease, and Lewy body dementia alter α-synuclein processing. Annals of Neurology. 69: 940-53. PMID 21472771 DOI: 10.1002/Ana.22400  0.366
2011 Dumitriu A, Pacheco CD, Wilk JB, Strathearn KE, Latourelle JC, Goldwurm S, Pezzoli G, Rochet JC, Lindquist S, Myers RH. Cyclin-G-associated kinase modifies α-synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD Study. Human Molecular Genetics. 20: 1478-87. PMID 21258085 DOI: 10.1093/Hmg/Ddr026  0.8
2010 Zheng B, Liao Z, Locascio JJ, Lesniak KA, Roderick SS, Watt ML, Eklund AC, Zhang-James Y, Kim PD, Hauser MA, Grünblatt E, Moran LB, Mandel SA, Riederer P, Miller RM, ... ... Rochet JC, et al. PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease. Science Translational Medicine. 2: 52ra73. PMID 20926834 DOI: 10.1126/Scitranslmed.3001059  0.395
2010 Haque F, Pandey AP, Cambrea LR, Rochet JC, Hovis JS. Adsorption of alpha-synuclein on lipid bilayers: modulating the structure and stability of protein assemblies. The Journal of Physical Chemistry. B. 114: 4070-81. PMID 20187615 DOI: 10.1021/Jp1006704  0.376
2010 Su LJ, Auluck PK, Outeiro TF, Yeger-Lotem E, Kritzer JA, Tardiff DF, Strathearn KE, Liu F, Cao S, Hamamichi S, Hill KJ, Caldwell KA, Bell GW, Fraenkel E, Cooper AA, ... ... Rochet JC, et al. Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models. Disease Models & Mechanisms. 3: 194-208. PMID 20038714 DOI: 10.1242/Dmm.004267  0.8
2009 Padalkar S, Hulleman J, Kim SM, Tumkur T, Rochet JC, Stach E, Stanciu L. Fabrication of ZnS nanoparticle chains on a protein template. Journal of Nanoparticle Research : An Interdisciplinary Forum For Nanoscale Science and Technology. 11: 2031-2041. PMID 21804765 DOI: 10.1007/S11051-009-9689-8  0.613
2009 Gitler AD, Chesi A, Geddie ML, Strathearn KE, Hamamichi S, Hill KJ, Caldwell KA, Caldwell GA, Cooper AA, Rochet JC, Lindquist S. Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity. Nature Genetics. 41: 308-15. PMID 19182805 DOI: 10.1038/Ng.300  0.806
2009 Pandey AP, Haque F, Rochet JC, Hovis JS. Clustering of alpha-synuclein on supported lipid bilayers: role of anionic lipid, protein, and divalent ion concentration. Biophysical Journal. 96: 540-51. PMID 19167303 DOI: 10.1016/J.Bpj.2008.10.011  0.373
2008 Padalkar S, Hulleman JD, Kim SM, Rochet JC, Stach EA, Stanciu LA. Protein-templated semiconductor nanoparticle chains. Nanotechnology. 19: 275602. PMID 21828709 DOI: 10.1088/0957-4484/19/27/275602  0.614
2008 Colby R, Hulleman J, Padalkar S, Rochet JC, Stanciu LA. Biotemplated synthesis of metallic nanoparticle chains on an alpha-synuclein fiber scaffold. Journal of Nanoscience and Nanotechnology. 8: 973-8. PMID 18464436 DOI: 10.1166/Jnn.2008.038  0.671
2008 Liu F, Hindupur J, Nguyen JL, Ruf KJ, Zhu J, Schieler JL, Bonham CC, Wood KV, Davisson VJ, Rochet JC. Methionine sulfoxide reductase A protects dopaminergic cells from Parkinson's disease-related insults. Free Radical Biology & Medicine. 45: 242-55. PMID 18456002 DOI: 10.1016/J.Freeradbiomed.2008.03.022  0.818
2008 Liu F, Nguyen JL, Hulleman JD, Li L, Rochet JC. Mechanisms of DJ-1 neuroprotection in a cellular model of Parkinson's disease. Journal of Neurochemistry. 105: 2435-53. PMID 18331584 DOI: 10.1111/J.1471-4159.2008.05333.X  0.76
2008 Gitler AD, Bevis BJ, Shorter J, Strathearn KE, Hamamichi S, Su LJ, Caldwell KA, Caldwell GA, Rochet JC, McCaffery JM, Barlowe C, Lindquist S. The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 105: 145-50. PMID 18162536 DOI: 10.1073/Pnas.0710685105  0.8
2008 Rochet JC, Schieler JL. The use of Cell-Free Systems to Characterize Parkinson's Disease-Related Gene Products Parkinson's Disease. 597-627. DOI: 10.1016/B978-0-12-374028-1.00043-9  0.762
2007 Zakharov SD, Hulleman JD, Dutseva EA, Antonenko YN, Rochet JC, Cramer WA. Helical alpha-synuclein forms highly conductive ion channels. Biochemistry. 46: 14369-79. PMID 18031063 DOI: 10.1021/Bi701275P  0.673
2007 Tammam SD, Rochet JC, Fraser ME. Identification of the cysteine residue exposed by the conformational change in pig heart succinyl-CoA:3-ketoacid coenzyme A transferase on binding coenzyme A. Biochemistry. 46: 10852-63. PMID 17718512 DOI: 10.1021/Bi700828H  0.302
2007 Rochet JC. Novel therapeutic strategies for the treatment of protein-misfolding diseases. Expert Reviews in Molecular Medicine. 9: 1-34. PMID 17597554 DOI: 10.1017/S1462399407000385  0.301
2007 Outeiro TF, Kontopoulos E, Altmann SM, Kufareva I, Strathearn KE, Amore AM, Volk CB, Maxwell MM, Rochet JC, McLean PJ, Young AB, Abagyan R, Feany MB, Hyman BT, Kazantsev AG. Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. Science (New York, N.Y.). 317: 516-9. PMID 17588900 DOI: 10.1126/Science.1143780  0.791
2007 Cambrea LR, Haque F, Schieler JL, Rochet JC, Hovis JS. Effect of ions on the organization of phosphatidylcholine/phosphatidic acid bilayers. Biophysical Journal. 93: 1630-8. PMID 17483164 DOI: 10.1529/Biophysj.107.104224  0.737
2007 Hulleman JD, Mirzaei H, Guigard E, Taylor KL, Ray SS, Kay CM, Regnier FE, Rochet JC. Destabilization of DJ-1 by familial substitution and oxidative modifications: implications for Parkinson's disease. Biochemistry. 46: 5776-89. PMID 17451229 DOI: 10.1021/Bi7001778  0.762
2007 Padalkar S, Hulleman J, Deb P, Cunzeman K, Rochet JC, Stach EA, Stanciu L. Metallic nanowires on a new protein template Proceedings of Spie - the International Society For Optical Engineering. 6592. DOI: 10.1117/12.722142  0.641
2007 Padalkar S, Hulleman J, Deb P, Cunzeman K, Rochet JC, Stach EA, Stanciu L. Alpha-synuclein as a template for the synthesis of metallic nanowires Nanotechnology. 18. DOI: 10.1088/0957-4484/18/5/055609  0.665
2006 Rochet JC. Errors in translation cause selective neurodegeneration. Acs Chemical Biology. 1: 562-6. PMID 17168550 DOI: 10.1021/Cb6004068  0.345
2006 Outeiro TF, Klucken J, Strathearn KE, Liu F, Nguyen P, Rochet JC, Hyman BT, McLean PJ. Small heat shock proteins protect against alpha-synuclein-induced toxicity and aggregation. Biochemical and Biophysical Research Communications. 351: 631-8. PMID 17081499 DOI: 10.1016/J.Bbrc.2006.10.085  0.798
2006 Cooper AA, Gitler AD, Cashikar A, Haynes CM, Hill KJ, Bhullar B, Liu K, Xu K, Strathearn KE, Liu F, Cao S, Caldwell KA, Caldwell GA, Marsischky G, Kolodner RD, ... ... Rochet JC, et al. Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models. Science (New York, N.Y.). 313: 324-8. PMID 16794039 DOI: 10.1126/Science.1129462  0.804
2006 Mirzaei H, Schieler JL, Rochet JC, Regnier F. Identification of rotenone-induced modifications in alpha-synuclein using affinity pull-down and tandem mass spectrometry. Analytical Chemistry. 78: 2422-31. PMID 16579629 DOI: 10.1021/Ac051978N  0.802
2006 Schieler J, Liu F, Mirzaei H, Bernas T, Robinson J, Regnier F, Rochet J. Effect of oxidative stress on α-synuclein aggregation in Parkinson's disease Nanomedicine: Nanotechnology, Biology and Medicine. 2: 317. DOI: 10.1016/J.Nano.2006.10.152  0.79
2004 Rochet JC, Outeiro TF, Conway KA, Ding TT, Volles MJ, Lashuel HA, Bieganski RM, Lindquist SL, Lansbury PT. Interactions among alpha-synuclein, dopamine, and biomembranes: some clues for understanding neurodegeneration in Parkinson's disease. Journal of Molecular Neuroscience : Mn. 23: 23-34. PMID 15126689 DOI: 10.1385/Jmn:23:1-2:023  0.388
2002 Ding TT, Lee SJ, Rochet JC, Lansbury PT. Annular alpha-synuclein protofibrils are produced when spherical protofibrils are incubated in solution or bound to brain-derived membranes. Biochemistry. 41: 10209-17. PMID 12162735 DOI: 10.1021/Bi020139H  0.363
2001 Conway KA, Rochet JC, Bieganski RM, Lansbury PT. Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct. Science (New York, N.Y.). 294: 1346-9. PMID 11701929 DOI: 10.1126/Science.1063522  0.461
2001 Volles MJ, Lee SJ, Rochet JC, Shtilerman MD, Ding TT, Kessler JC, Lansbury PT. Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease. Biochemistry. 40: 7812-9. PMID 11425308 DOI: 10.1021/Bi0102398  0.405
2000 Conway KA, Lee SJ, Rochet JC, Ding TT, Harper JD, Williamson RE, Lansbury PT. Accelerated oligomerization by Parkinson's disease linked alpha-synuclein mutants. Annals of the New York Academy of Sciences. 920: 42-5. PMID 11193175 DOI: 10.1111/J.1749-6632.2000.Tb06903.X  0.33
2000 Rochet JC, Brownie ER, Oikawa K, Hicks LD, Fraser ME, James MN, Kay CM, Bridger WA, Wolodko WT. Pig heart CoA transferase exists as two oligomeric forms separated by a large kinetic barrier. Biochemistry. 39: 11291-302. PMID 10985774 DOI: 10.1021/Bi0003184  0.758
2000 Rochet JC, Conway KA, Lansbury PT. Inhibition of fibrillization and accumulation of prefibrillar oligomers in mixtures of human and mouse alpha-synuclein. Biochemistry. 39: 10619-26. PMID 10978144 DOI: 10.1021/Bi001315U  0.418
2000 Conway KA, Lee SJ, Rochet JC, Ding TT, Williamson RE, Lansbury PT. Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy. Proceedings of the National Academy of Sciences of the United States of America. 97: 571-6. PMID 10639120 DOI: 10.1073/Pnas.97.2.571  0.365
1997 Rochet JC, Oikawa K, Hicks LD, Kay CM, Bridger WA, Wolodko WT. Productive interactions between the two domains of pig heart CoA transferase during folding and assembly. Biochemistry. 36: 8807-20. PMID 9220967 DOI: 10.1021/Bi9703002  0.753
1997 Rochet JC, Bridger WA, Wolodko WT. The aggregation of the C-domain of pig heart CoA transferase: Implications on the folding pathway of the intact enzyme Protein Engineering. 10: 34.  0.593
1994 Rochet JC, Bridger WA. Identification of glutamate 344 as the catalytic residue in the active site of pig heart CoA transferase. Protein Science : a Publication of the Protein Society. 3: 975-81. PMID 7915164 DOI: 10.1002/Pro.5560030613  0.573
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