| Year |
Citation |
Score |
| 2020 |
Landeck N, Strathearn KE, Ysselstein D, Buck K, Dutta S, Banerjee S, Lv Z, Hulleman JD, Hindupur J, Lin LK, Padalkar S, Stanciu LA, Lyubchenko YL, Kirik D, Rochet JC. Two C-terminal sequence variations determine differential neurotoxicity between human and mouse α-synuclein. Molecular Neurodegeneration. 15: 49. PMID 32900375 DOI: 10.1186/s13024-020-00380-w |
0.52 |
|
| 2019 |
Lv Z, Hashemi M, Banerjee S, Zagorski K, Rochet JC, Lyubchenko YL. Assembly of α-synuclein aggregates on phospholipid bilayers. Biochimica Et Biophysica Acta. Proteins and Proteomics. PMID 31226488 DOI: 10.1016/j.bbapap.2019.06.006 |
0.44 |
|
| 2018 |
Ambaw A, Zheng L, Tambe MA, Strathearn KE, Acosta G, Hubers SA, Liu F, Herr SA, Tang J, Truong A, Walls E, Pond A, Rochet JC, Shi R. Acrolein-mediated neuronal cell death and alpha-synuclein aggregation: Implications for Parkinson's disease. Molecular and Cellular Neurosciences. 88: 70-82. PMID 29414104 DOI: 10.1016/j.mcn.2018.01.006 |
0.44 |
|
| 2017 |
Collier TJ, Srivastava KR, Justman C, Grammatopoulous T, Hutter-Paier B, Prokesch M, Havas D, Rochet JC, Liu F, Jock K, de Oliveira P, Stirtz GL, Dettmer U, Sortwell CE, Feany MB, et al. Nortriptyline inhibits aggregation and neurotoxicity of alpha-synuclein by enhancing reconfiguration of the monomeric form. Neurobiology of Disease. PMID 28711409 DOI: 10.1016/j.nbd.2017.07.007 |
0.44 |
|
| 2017 |
Banerjee S, Hashemi M, Lv Z, Maity S, Rochet JC, Lyubchenko YL. A novel pathway for amyloids self-assembly in aggregates at nanomolar concentration mediated by the interaction with surfaces. Scientific Reports. 7: 45592. PMID 28358113 DOI: 10.1038/srep45592 |
0.44 |
|
| 2016 |
Lv Z, Krasnoslobodtsev AV, Zhang Y, Ysselstein D, Rochet JC, Blanchard SC, Lyubchenko YL. Effect of acidic pH on the stability of α-Synuclein dimers. Biopolymers. PMID 27177831 DOI: 10.1002/bip.22874 |
0.44 |
|
| 2015 |
Tsai CJ, Aslam K, Drendel HM, Asiago JM, Goode KM, Paul LN, Rochet JC, Hazbun TR. Hsp31 Is a Stress Response Chaperone That Intervenes in the Protein Misfolding Process. The Journal of Biological Chemistry. 290: 24816-34. PMID 26306045 DOI: 10.1074/jbc.M115.678367 |
0.44 |
|
| 2015 |
Zhang H, Rochet JC, Stanciu LA. Cu(II) promotes amyloid pore formation. Biochemical and Biophysical Research Communications. PMID 26129772 DOI: 10.1016/j.bbrc.2015.06.156 |
1 |
|
| 2015 |
Ysselstein D, Joshi M, Mishra V, Griggs AM, Asiago JM, McCabe GP, Stanciu LA, Post CB, Rochet JC. Effects of impaired membrane interactions on α-synuclein aggregation and neurotoxicity. Neurobiology of Disease. 79: 150-63. PMID 25931201 DOI: 10.1016/j.nbd.2015.04.007 |
1 |
|
| 2015 |
Lv Z, Krasnoslobodtsev AV, Zhang Y, Ysselstein D, Rochet JC, Blanchard SC, Lyubchenko YL. Direct Detection of α-Synuclein Dimerization Dynamics: Single-Molecule Fluorescence Analysis. Biophysical Journal. 108: 2038-47. PMID 25902443 DOI: 10.1016/j.bpj.2015.03.010 |
1 |
|
| 2015 |
Tsai CJ, Aslam K, Drendel HM, Asiago JM, Goode KM, Paul LN, Rochet JC, Hazbun TR. Hsp31 is a stress response chaperone that intervenes in the protein misfolding process Journal of Biological Chemistry. 290: 24816-24834. DOI: 10.1074/jbc.M115.678367 |
1 |
|
| 2014 |
Griggs AM, Agim ZS, Mishra VR, Tambe MA, Director-Myska AE, Turteltaub KW, McCabe GP, Rochet JC, Cannon JR. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is selectively toxic to primary dopaminergic neurons in vitro. Toxicological Sciences : An Official Journal of the Society of Toxicology. 140: 179-89. PMID 24718704 DOI: 10.1093/toxsci/kfu060 |
1 |
|
| 2014 |
de Rus Jacquet A, Subedi R, Ghimire SK, Rochet JC. Nepalese traditional medicine and symptoms related to Parkinson's disease and other disorders: Patterns of the usage of plant resources along the Himalayan altitudinal range. Journal of Ethnopharmacology. 153: 178-89. PMID 24556225 DOI: 10.1016/j.jep.2014.02.016 |
1 |
|
| 2014 |
Tóth G, Gardai SJ, Zago W, Bertoncini CW, Cremades N, Roy SL, Tambe MA, Rochet JC, Galvagnion C, Skibinski G, Finkbeiner S, Bova M, Regnstrom K, Chiou SS, Johnston J, et al. Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease. Plos One. 9: e87133. PMID 24551051 DOI: 10.1371/journal.pone.0087133 |
1 |
|
| 2014 |
Strathearn KE, Yousef GG, Grace MH, Roy SL, Tambe MA, Ferruzzi MG, Wu QL, Simon JE, Lila MA, Rochet JC. Neuroprotective effects of anthocyanin- and proanthocyanidin-rich extracts in cellular models of Parkinson׳s disease. Brain Research. 1555: 60-77. PMID 24502982 DOI: 10.1016/j.brainres.2014.01.047 |
1 |
|
| 2014 |
Anandhan A, Rodriguez-Rocha H, Bohovych I, Griggs AM, Zavala-Flores L, Reyes-Reyes EM, Seravalli J, Stanciu LA, Lee J, Rochet JC, Khalimonchuk O, Franco R. Overexpression of alpha-synuclein at non-toxic levels increases dopaminergic cell death induced by copper exposure via modulation of protein degradation pathways Neurobiology of Disease. DOI: 10.1016/j.nbd.2014.11.018 |
1 |
|
| 2013 |
Krasnoslobodtsev AV, Volkov IL, Asiago JM, Hindupur J, Rochet JC, Lyubchenko YL. α-Synuclein misfolding assessed with single molecule AFM force spectroscopy: effect of pathogenic mutations. Biochemistry. 52: 7377-86. PMID 24066883 DOI: 10.1021/bi401037z |
1 |
|
| 2013 |
Zhang H, Griggs A, Rochet JC, Stanciu LA. In vitro study of α-synuclein protofibrils by cryo-EM suggests a Cu(2+)-dependent aggregation pathway. Biophysical Journal. 104: 2706-13. PMID 23790379 DOI: 10.1016/j.bpj.2013.04.050 |
1 |
|
| 2013 |
Snyder A, Bo Z, Moon R, Rochet JC, Stanciu L. Reusable photocatalytic titanium dioxide-cellulose nanofiber films. Journal of Colloid and Interface Science. 399: 92-8. PMID 23534970 DOI: 10.1016/j.jcis.2013.02.035 |
1 |
|
| 2013 |
Griggs AM, Ysselstein D, Rochet JC. Role of Aberrant α-Synuclein-Membrane Interactions in Parkinson's Disease Bio-Nanoimaging: Protein Misfolding and Aggregation. 443-452. DOI: 10.1016/B978-0-12-394431-3.00039-0 |
1 |
|
| 2012 |
Krasnoslobodtsev AV, Peng J, Asiago JM, Hindupur J, Rochet JC, Lyubchenko YL. Effect of spermidine on misfolding and interactions of alpha-synuclein. Plos One. 7: e38099. PMID 22662273 DOI: 10.1371/journal.pone.0038099 |
1 |
|
| 2012 |
Rochet JC, Hay BA, Guo M. Molecular insights into Parkinson's disease. Progress in Molecular Biology and Translational Science. 107: 125-88. PMID 22482450 DOI: 10.1016/B978-0-12-385883-2.00011-4 |
1 |
|
| 2012 |
Madian AG, Hindupur J, Hulleman JD, Diaz-Maldonado N, Mishra VR, Guigard E, Kay CM, Rochet JC, Regnier FE. Effect of single amino acid substitution on oxidative modifications of the Parkinson's disease-related protein, DJ-1. Molecular & Cellular Proteomics : McP. 11: M111.010892. PMID 22104028 DOI: 10.1074/mcp.M111.010892 |
1 |
|
| 2012 |
Rochet JC. New insights into lysosomal dysfunction in parkinson's disease: An emerging role for ATP13A2 Movement Disorders. 27: 1092-1092. DOI: 10.1002/mds.25118 |
1 |
|
| 2011 |
Cramer WA, Zakharov SD, Saif Hasan S, Zhang H, Baniulis D, Zhalnina MV, Soriano GM, Sharma O, Rochet JC, Ryan C, Whitelegge J, Kurisu G, Yamashita E. Membrane proteins in four acts: function precedes structure determination. Methods (San Diego, Calif.). 55: 415-20. PMID 22079407 DOI: 10.1016/j.ymeth.2011.11.001 |
1 |
|
| 2011 |
Pandey AP, Haque F, Rochet JC, Hovis JS. α-Synuclein-induced tubule formation in lipid bilayers. The Journal of Physical Chemistry. B. 115: 5886-93. PMID 21520980 DOI: 10.1021/jp1121917 |
1 |
|
| 2011 |
Cullen V, Sardi SP, Ng J, Xu YH, Sun Y, Tomlinson JJ, Kolodziej P, Kahn I, Saftig P, Woulfe J, Rochet JC, Glicksman MA, Cheng SH, Grabowski GA, Shihabuddin LS, et al. Acid β-glucosidase mutants linked to Gaucher disease, Parkinson disease, and Lewy body dementia alter α-synuclein processing. Annals of Neurology. 69: 940-53. PMID 21472771 DOI: 10.1002/ana.22400 |
1 |
|
| 2011 |
Dumitriu A, Pacheco CD, Wilk JB, Strathearn KE, Latourelle JC, Goldwurm S, Pezzoli G, Rochet JC, Lindquist S, Myers RH. Cyclin-G-associated kinase modifies α-synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD Study. Human Molecular Genetics. 20: 1478-87. PMID 21258085 DOI: 10.1093/hmg/ddr026 |
1 |
|
| 2010 |
Zheng B, Liao Z, Locascio JJ, Lesniak KA, Roderick SS, Watt ML, Eklund AC, Zhang-James Y, Kim PD, Hauser MA, Grünblatt E, Moran LB, Mandel SA, Riederer P, Miller RM, ... ... Rochet JC, et al. PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease. Science Translational Medicine. 2: 52ra73. PMID 20926834 DOI: 10.1126/scitranslmed.3001059 |
1 |
|
| 2010 |
Haque F, Pandey AP, Cambrea LR, Rochet JC, Hovis JS. Adsorption of alpha-synuclein on lipid bilayers: modulating the structure and stability of protein assemblies. The Journal of Physical Chemistry. B. 114: 4070-81. PMID 20187615 DOI: 10.1021/jp1006704 |
1 |
|
| 2010 |
Su LJ, Auluck PK, Outeiro TF, Yeger-Lotem E, Kritzer JA, Tardiff DF, Strathearn KE, Liu F, Cao S, Hamamichi S, Hill KJ, Caldwell KA, Bell GW, Fraenkel E, Cooper AA, ... ... Rochet JC, et al. Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models. Disease Models & Mechanisms. 3: 194-208. PMID 20038714 DOI: 10.1242/dmm.004267 |
1 |
|
| 2009 |
Padalkar S, Hulleman J, Kim SM, Tumkur T, Rochet JC, Stach E, Stanciu L. Fabrication of ZnS nanoparticle chains on a protein template. Journal of Nanoparticle Research : An Interdisciplinary Forum For Nanoscale Science and Technology. 11: 2031-2041. PMID 21804765 DOI: 10.1007/s11051-009-9689-8 |
1 |
|
| 2009 |
Lamberson ER, Cambrea LR, Rochet JC, Hovis JS. Path dependence of three-phase or two-phase end points in fluid binary lipid mixtures. The Journal of Physical Chemistry. B. 113: 3431-6. PMID 19243147 DOI: 10.1021/jp810326w |
1 |
|
| 2009 |
Gitler AD, Chesi A, Geddie ML, Strathearn KE, Hamamichi S, Hill KJ, Caldwell KA, Caldwell GA, Cooper AA, Rochet JC, Lindquist S. Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity. Nature Genetics. 41: 308-15. PMID 19182805 DOI: 10.1038/ng.300 |
1 |
|
| 2009 |
Pandey AP, Haque F, Rochet JC, Hovis JS. Clustering of alpha-synuclein on supported lipid bilayers: role of anionic lipid, protein, and divalent ion concentration. Biophysical Journal. 96: 540-51. PMID 19167303 DOI: 10.1016/j.bpj.2008.10.011 |
1 |
|
| 2008 |
Padalkar S, Hulleman JD, Kim SM, Rochet JC, Stach EA, Stanciu LA. Protein-templated semiconductor nanoparticle chains. Nanotechnology. 19: 275602. PMID 21828709 DOI: 10.1088/0957-4484/19/27/275602 |
1 |
|
| 2008 |
Colby R, Hulleman J, Padalkar S, Rochet JC, Stanciu LA. Biotemplated synthesis of metallic nanoparticle chains on an alpha-synuclein fiber scaffold. Journal of Nanoscience and Nanotechnology. 8: 973-8. PMID 18464436 DOI: 10.1166/jnn.2008.038 |
1 |
|
| 2008 |
Liu F, Hindupur J, Nguyen JL, Ruf KJ, Zhu J, Schieler JL, Bonham CC, Wood KV, Davisson VJ, Rochet JC. Methionine sulfoxide reductase A protects dopaminergic cells from Parkinson's disease-related insults. Free Radical Biology & Medicine. 45: 242-55. PMID 18456002 DOI: 10.1016/j.freeradbiomed.2008.03.022 |
1 |
|
| 2008 |
Liu F, Nguyen JL, Hulleman JD, Li L, Rochet JC. Mechanisms of DJ-1 neuroprotection in a cellular model of Parkinson's disease. Journal of Neurochemistry. 105: 2435-53. PMID 18331584 DOI: 10.1111/j.1471-4159.2008.05333.x |
1 |
|
| 2008 |
Gitler AD, Bevis BJ, Shorter J, Strathearn KE, Hamamichi S, Su LJ, Caldwell KA, Caldwell GA, Rochet JC, McCaffery JM, Barlowe C, Lindquist S. The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 105: 145-50. PMID 18162536 DOI: 10.1073/pnas.0710685105 |
1 |
|
| 2008 |
Rochet JC, Schieler JL. The use of Cell-Free Systems to Characterize Parkinson's Disease-Related Gene Products Parkinson's Disease. 597-627. DOI: 10.1016/B978-0-12-374028-1.00043-9 |
1 |
|
| 2007 |
Zakharov SD, Hulleman JD, Dutseva EA, Antonenko YN, Rochet JC, Cramer WA. Helical alpha-synuclein forms highly conductive ion channels. Biochemistry. 46: 14369-79. PMID 18031063 DOI: 10.1021/bi701275p |
1 |
|
| 2007 |
Tammam SD, Rochet JC, Fraser ME. Identification of the cysteine residue exposed by the conformational change in pig heart succinyl-CoA:3-ketoacid coenzyme A transferase on binding coenzyme A. Biochemistry. 46: 10852-63. PMID 17718512 DOI: 10.1021/bi700828h |
1 |
|
| 2007 |
Rochet JC. Novel therapeutic strategies for the treatment of protein-misfolding diseases. Expert Reviews in Molecular Medicine. 9: 1-34. PMID 17597554 DOI: 10.1017/S1462399407000385 |
1 |
|
| 2007 |
Outeiro TF, Kontopoulos E, Altmann SM, Kufareva I, Strathearn KE, Amore AM, Volk CB, Maxwell MM, Rochet JC, McLean PJ, Young AB, Abagyan R, Feany MB, Hyman BT, Kazantsev AG. Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. Science (New York, N.Y.). 317: 516-9. PMID 17588900 DOI: 10.1126/science.1143780 |
1 |
|
| 2007 |
Cambrea LR, Haque F, Schieler JL, Rochet JC, Hovis JS. Effect of ions on the organization of phosphatidylcholine/phosphatidic acid bilayers. Biophysical Journal. 93: 1630-8. PMID 17483164 DOI: 10.1529/biophysj.107.104224 |
1 |
|
| 2007 |
Hulleman JD, Mirzaei H, Guigard E, Taylor KL, Ray SS, Kay CM, Regnier FE, Rochet JC. Destabilization of DJ-1 by familial substitution and oxidative modifications: implications for Parkinson's disease. Biochemistry. 46: 5776-89. PMID 17451229 DOI: 10.1021/bi7001778 |
1 |
|
| 2007 |
Padalkar S, Hulleman J, Deb P, Cunzeman K, Rochet JC, Stach EA, Stanciu L. Metallic nanowires on a new protein template Proceedings of Spie - the International Society For Optical Engineering. 6592. DOI: 10.1117/12.722142 |
1 |
|
| 2007 |
Padalkar S, Hulleman J, Deb P, Cunzeman K, Rochet JC, Stach EA, Stanciu L. Alpha-synuclein as a template for the synthesis of metallic nanowires Nanotechnology. 18. DOI: 10.1088/0957-4484/18/5/055609 |
1 |
|
| 2006 |
Rochet JC. Errors in translation cause selective neurodegeneration. Acs Chemical Biology. 1: 562-6. PMID 17168550 DOI: 10.1021/cb6004068 |
1 |
|
| 2006 |
Outeiro TF, Klucken J, Strathearn KE, Liu F, Nguyen P, Rochet JC, Hyman BT, McLean PJ. Small heat shock proteins protect against alpha-synuclein-induced toxicity and aggregation. Biochemical and Biophysical Research Communications. 351: 631-8. PMID 17081499 DOI: 10.1016/j.bbrc.2006.10.085 |
1 |
|
| 2006 |
Cooper AA, Gitler AD, Cashikar A, Haynes CM, Hill KJ, Bhullar B, Liu K, Xu K, Strathearn KE, Liu F, Cao S, Caldwell KA, Caldwell GA, Marsischky G, Kolodner RD, ... ... Rochet JC, et al. Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models. Science (New York, N.Y.). 313: 324-8. PMID 16794039 DOI: 10.1126/science.1129462 |
1 |
|
| 2006 |
Mirzaei H, Schieler JL, Rochet JC, Regnier F. Identification of rotenone-induced modifications in alpha-synuclein using affinity pull-down and tandem mass spectrometry. Analytical Chemistry. 78: 2422-31. PMID 16579629 DOI: 10.1021/ac051978n |
1 |
|
| 2004 |
Rochet JC, Outeiro TF, Conway KA, Ding TT, Volles MJ, Lashuel HA, Bieganski RM, Lindquist SL, Lansbury PT. Interactions among alpha-synuclein, dopamine, and biomembranes: some clues for understanding neurodegeneration in Parkinson's disease. Journal of Molecular Neuroscience : Mn. 23: 23-34. PMID 15126689 DOI: 10.1385/JMN:23:1-2:023 |
1 |
|
| 2003 |
Kessler JC, Rochet JC, Lansbury PT. The N-terminal repeat domain of alpha-synuclein inhibits beta-sheet and amyloid fibril formation. Biochemistry. 42: 672-8. PMID 12534279 DOI: 10.1021/bi020429y |
1 |
|
| 2002 |
Ding TT, Lee SJ, Rochet JC, Lansbury PT. Annular alpha-synuclein protofibrils are produced when spherical protofibrils are incubated in solution or bound to brain-derived membranes. Biochemistry. 41: 10209-17. PMID 12162735 DOI: 10.1021/bi020139h |
1 |
|
| 2001 |
Conway KA, Rochet JC, Bieganski RM, Lansbury PT. Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct. Science (New York, N.Y.). 294: 1346-9. PMID 11701929 DOI: 10.1126/science.1063522 |
1 |
|
| 2001 |
Volles MJ, Lee SJ, Rochet JC, Shtilerman MD, Ding TT, Kessler JC, Lansbury PT. Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease. Biochemistry. 40: 7812-9. PMID 11425308 DOI: 10.1021/bi0102398 |
1 |
|
| 2000 |
Conway KA, Lee SJ, Rochet JC, Ding TT, Harper JD, Williamson RE, Lansbury PT. Accelerated oligomerization by Parkinson's disease linked alpha-synuclein mutants. Annals of the New York Academy of Sciences. 920: 42-5. PMID 11193175 DOI: 10.1111/j.1749-6632.2000.tb06903.x |
1 |
|
| 2000 |
Rochet JC, Brownie ER, Oikawa K, Hicks LD, Fraser ME, James MN, Kay CM, Bridger WA, Wolodko WT. Pig heart CoA transferase exists as two oligomeric forms separated by a large kinetic barrier. Biochemistry. 39: 11291-302. PMID 10985774 DOI: 10.1021/bi0003184 |
1 |
|
| 2000 |
Rochet JC, Conway KA, Lansbury PT. Inhibition of fibrillization and accumulation of prefibrillar oligomers in mixtures of human and mouse alpha-synuclein. Biochemistry. 39: 10619-26. PMID 10978144 DOI: 10.1021/bi001315u |
1 |
|
| 2000 |
Rochet JC, Lansbury PT. Amyloid fibrillogenesis: themes and variations. Current Opinion in Structural Biology. 10: 60-8. PMID 10679462 DOI: 10.1016/S0959-440X(99)00049-4 |
1 |
|
| 2000 |
Conway KA, Lee SJ, Rochet JC, Ding TT, Williamson RE, Lansbury PT. Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy. Proceedings of the National Academy of Sciences of the United States of America. 97: 571-6. PMID 10639120 DOI: 10.1073/pnas.97.2.571 |
1 |
|
| 1997 |
Rochet JC, Oikawa K, Hicks LD, Kay CM, Bridger WA, Wolodko WT. Productive interactions between the two domains of pig heart CoA transferase during folding and assembly. Biochemistry. 36: 8807-20. PMID 9220967 DOI: 10.1021/bi9703002 |
1 |
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| 1997 |
Rochet JC, Bridger WA, Wolodko WT. The aggregation of the C-domain of pig heart CoA transferase: Implications on the folding pathway of the intact enzyme Protein Engineering. 10: 34. |
1 |
|
| 1994 |
Rochet JC, Bridger WA. Identification of glutamate 344 as the catalytic residue in the active site of pig heart CoA transferase. Protein Science : a Publication of the Protein Society. 3: 975-81. PMID 7915164 DOI: 10.1002/pro.5560030613 |
1 |
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