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Emily J. Parker, Ph.D. - Publications

Affiliations: 
1991-1998 Chemistry University of Cambridge, Cambridge, England, United Kingdom 
 1998-2006 Massey University, Palmerston North, Manawatu-Wanganui, New Zealand 
 2006- Biomolecular Interaction Centre University of Canterbury, New Zealand, Christchurch, Canterbury, New Zealand 
Area:
Bioorganic
Website:
http://www.chem.canterbury.ac.nz/people/parker.shtml

131 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Bai Y, Parker EJ. Reciprocal allostery arising from a bi-enzyme assembly controls aromatic amino acid biosynthesis in Prevotella nigrescens. The Journal of Biological Chemistry. 101038. PMID 34343567 DOI: 10.1016/j.jbc.2021.101038  1
2020 Jiao W, Lang EJ, Bai Y, Fan Y, Parker EJ. Diverse allosteric componentry and mechanisms control entry into aromatic metabolite biosynthesis. Current Opinion in Structural Biology. 65: 159-167. PMID 32739636 DOI: 10.1016/J.Sbi.2020.06.015  1
2020 Lacaze P, Sebra R, Riaz M, Tiller J, Revote J, Phung J, Parker EJ, Orchard SG, Lockery JE, Wolfe R, Strahl M, Wang YC, Chen R, Sisco D, Arnold T, et al. Medically actionable pathogenic variants in a population of 13,131 healthy elderly individuals. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 32606442 DOI: 10.1038/S41436-020-0881-7  0.04
2020 Jiao W, Fan Y, Blackmore NJ, Parker EJ. A single amino acid substitution uncouples catalysis and allostery in an essential biosynthetic enzyme in Mycobacterium tuberculosis. The Journal of Biological Chemistry. PMID 32217694 DOI: 10.1074/Jbc.Ra120.012605  1
2020 Rutherford C, Ewan L, Parker E, Wilson C, Romics L, Stallard S. P082: Magseed experience - A single centre prospective study Ejso. 46. DOI: 10.1016/J.Ejso.2020.03.121  0.01
2019 Van de Bittner KC, Cameron RC, Bustamante LY, Bundela R, Kessans SA, Vorster J, Nicholson MJ, Parker EJ. Nodulisporic acid E biosynthesis: characterisation of NodD1, an indole-diterpene prenyltransferase that acts on an emindole SB derived indole-diterpene scaffold. Medchemcomm. 10: 1160-1164. PMID 31391888 DOI: 10.1039/C9Md00143C  1
2019 Jiao W, Mittelstädt G, Moggré GJ, Parker EJ. Hinge Twists and Population Shifts Deliver Regulated Catalysis for ATP-PRT in Histidine Biosynthesis. Biophysical Journal. PMID 31053263 DOI: 10.1016/J.Bpj.2019.03.040  1
2019 Bai Y, Lang EJM, Nazmi AR, Parker EJ. Domain cross-talk within a bifunctional enzyme provides catalytic and allosteric functionality in the biosynthesis of aromatic amino acids. The Journal of Biological Chemistry. PMID 30670586 DOI: 10.1074/Jbc.Ra118.005220  1
2018 Sterritt OW, Lang EJM, Kessans SA, Ryan TM, Demeler B, Jameson GB, Parker EJ. The short-form type II DAH7PS from , associated with phenazine biosynthesis, suggests reclassification of type II enzymes. Bioscience Reports. PMID 30242059 DOI: 10.1042/Bsr20181605  1
2018 Heikal A, Nakatani Y, Jiao W, Wilson C, Rennison D, Weimar MR, Parker EJ, Brimble MA, Cook GM. 'Tethering' fragment-based drug discovery to identify inhibitors of the essential respiratory membrane protein type II NADH dehydrogenase. Bioorganic & Medicinal Chemistry Letters. PMID 29859905 DOI: 10.1016/J.Bmcl.2018.05.048  1
2018 Petri J, Shimaki Y, Jiao W, Bridges HR, Russell ER, Parker EJ, Aragão D, Cook GM, Nakatani Y. Structure of the NDH-2 - HQNO inhibited complex provides molecular insight into quinone-binding site inhibitors. Biochimica Et Biophysica Acta. PMID 29621505 DOI: 10.1016/J.Bbabio.2018.03.014  1
2018 van Dolleweerd CJ, Kessans SA, Van de Bittner KC, Bustamante LY, Bundela R, Scott B, Nicholson MJ, Parker EJ. MIDAS: A modular DNA assembly system for synthetic biology. Acs Synthetic Biology. PMID 29620866 DOI: 10.1021/Acssynbio.7B00363  1
2018 Sterritt O, Kessans SA, Jameson GB, Parker EJ. A pseudo-isostructural type II DAH7PS enzyme from Pseudomonas aeruginosa: alternative evolutionary strategies to control shikimate pathway flux. Biochemistry. PMID 29608284 DOI: 10.1021/Acs.Biochem.8B00082  1
2018 Fan Y, Cross PJ, Jameson GB, Parker EJ. Exploring modular allostery via interchangeable regulatory domains. Proceedings of the National Academy of Sciences of the United States of America. PMID 29507215 DOI: 10.1073/Pnas.1717621115  1
2018 Nicholson MJ, Van de Bittner KC, Ram A, Bustamante LY, Scott B, Parker EJ. Draft Genome Sequence of the Filamentous Fungus Hypoxylon pulicicidum ATCC 74245. Genome Announcements. 6. PMID 29326208 DOI: 10.1128/Genomea.01380-17  1
2017 Van de Bittner KC, Nicholson MJ, Bustamante LY, Kessans SA, Ram A, van Dolleweerd CJ, Scott B, Parker EJ. HETEROLOGOUS BIOSYNTHESIS OF NODULISPORIC ACID F. Journal of the American Chemical Society. PMID 29283570 DOI: 10.1021/jacs.7b10909  1
2017 Mittelstädt G, Jiao W, Livingstone E, Moggré GJ, Nazmi AR, Parker EJ. A dimeric catalytic core relates the short and long forms of ATP-phosphoribosyltransferase. The Biochemical Journal. PMID 29208762 DOI: 10.1042/Bcj20170762  1
2017 Evans GL, Furkert DP, Abermil N, Kundu P, de Lange KM, Parker EJ, Brimble MA, Baker EN, Lott JS. Datasets, processing and refinement details for Mtb-AnPRT: inhibitor structures with various space groups. Data in Brief. 15: 1019-1029. PMID 29167811 DOI: 10.1016/J.Dib.2017.10.051  1
2017 Nakatani Y, Jiao W, Aragão D, Shimaki Y, Petri J, Parker EJ, Cook GM. Crystal structure of type II NADH:quinone oxidoreductase from Caldalkalibacillus thermarum with an improved resolution of 2.15 Å. Acta Crystallographica. Section F, Structural Biology Communications. 73: 541-549. PMID 28994401 DOI: 10.1107/S2053230X17013073  1
2017 Moggré GJ, Poulin MB, Tyler PC, Schramm VL, Parker EJ. Transition state analysis of adenosine triphosphate phosphoribosyltransferase. Acs Chemical Biology. PMID 28872824 DOI: 10.1021/Acschembio.7B00484  1
2017 Evans GL, Furkert DP, Abermil N, Kundu P, de Lange KM, Parker EJ, Brimble MA, Baker EN, Shaun Lott J. Anthranilate phosphoribosyltransferase: Binding determinants for 5'-phospho-alpha-d-ribosyl-1'-pyrophosphate (PRPP) and the implications for inhibitor design. Biochimica Et Biophysica Acta. PMID 28844746 DOI: 10.1016/J.Bbapap.2017.08.018  1
2017 Jiao W, Blackmore NJ, Nazmi AR, Parker EJ. Quaternary structure is an essential component that contributes to the sophisticated allosteric regulation mechanism in a key enzyme from Mycobacterium tuberculosis. Plos One. 12: e0180052. PMID 28665948 DOI: 10.1371/Journal.Pone.0180052  1
2017 Hobbs JK, Jiao W, Easter AD, Parker EJ, Schipper LA, Arcus VL. Change in Heat Capacity for Enzyme Catalysis Determines Temperature Dependence of Enzyme Catalyzed Rates. Acs Chemical Biology. PMID 28221017 DOI: 10.1021/acschembio.7b00065  1
2016 Nazmi AR, Lang EJ, Bai Y, Allison TM, Othman MH, Panjikar S, Arcus VL, Parker EJ. Interdomain Conformational Changes Provide Allosteric Regulation En Route To Chorismate. The Journal of Biological Chemistry. PMID 27502275 DOI: 10.1074/Jbc.M116.741637  1
2016 Livingstone EK, Mittelstädt G, Given FM, Parker EJ. Independent catalysis of the short form HisG from Lactococcus lactis. Febs Letters. PMID 27393206 DOI: 10.1002/1873-3468.12277  1
2016 Mittelstädt G, Moggré GJ, Panjikar S, Nazmi AR, Parker EJ. Campylobacter jejuni adenosine triphosphate phosphoribosyltransferase is an active hexamer which is allosterically controlled by the twisting of a regulatory tail. Protein Science : a Publication of the Protein Society. PMID 27191057 DOI: 10.1002/Pro.2948  1
2016 Reichau S, Blackmore NJ, Jiao W, Parker EJ. Probing the Sophisticated Synergistic Allosteric Regulation of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis Using ᴅ-Amino Acids. Plos One. 11: e0152723. PMID 27128682 DOI: 10.1371/Journal.Pone.0152723  1
2016 Arturo EC, Gupta K, Héroux A, Stith L, Cross PJ, Parker EJ, Loll PJ, Jaffe EK. First structure of full-length mammalian phenylalanine hydroxylase reveals the architecture of an autoinhibited tetramer. Proceedings of the National Academy of Sciences of the United States of America. PMID 26884182 DOI: 10.1073/Pnas.1516967113  1
2016 Arcus VL, Prentice EJ, Hobbs JK, Mulholland AJ, van der Kamp MW, Pudney CR, Parker EJ, Schipper LA. On the Temperature Dependence of Enzyme-catalyzed Rates. Biochemistry. PMID 26881922 DOI: 10.1021/Acs.Biochem.5B01094  1
2016 Cross PJ, Heyes LC, Zhang S, Nazmi AR, Parker EJ. The Functional Unit of Neisseria meningitidis 3-Deoxy-ᴅ-Arabino-Heptulosonate 7-Phosphate Synthase Is Dimeric. Plos One. 11: e0145187. PMID 26828675 DOI: 10.1371/Journal.Pone.0145187  1
2016 Lang EJ, Heyes LC, Jameson GB, Parker EJ. Calculated pKa variations expose dynamic allosteric communication networks. Journal of the American Chemical Society. PMID 26794122 DOI: 10.1021/Jacs.5B13134  1
2016 Parker EJ, Mills H, John Spencer A, Mejia GC, Roberts-Thomson KF, Jamieson LM. Oral health impact among rural-dwelling indigenous adults in South Australia Journal of Health Care For the Poor and Underserved. 27: 207-219. DOI: 10.1353/hpu.2016.0033  1
2016 Jones K, Parker EJ, Steffens MA, Logan RM, Brennan D, Jamieson LM. Development and psychometric validation of social cognitive theory scales in an oral health context Australian and New Zealand Journal of Public Health. DOI: 10.1111/1753-6405.12500  1
2015 Cookson TV, Evans GL, Castell A, Baker EN, Lott JS, Parker EJ. Structures of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Variants Reveal the Conformational Changes That Facilitate Delivery of the Substrate to the Active Site. Biochemistry. 54: 6082-92. PMID 26356348 DOI: 10.1021/Acs.Biochem.5B00612  1
2015 Jamieson LM, Parker EJ, Broughton J, Lawrence HP, Armfield JM. Are Stage of Change constructs relevant for subjective oral health in a vulnerable population? Community Dental Health. 32: 111-6. PMID 26263605  0.01
2015 Blackmore NJ, Nazmi AR, Hutton RD, Webby MN, Baker EN, Jameson GB, Parker EJ. Complex Formation between Two Biosynthetic Enzymes Modifies the Allosteric Regulatory Properties of Both: AN EXAMPLE OF MOLECULAR SYMBIOSIS. The Journal of Biological Chemistry. 290: 18187-98. PMID 26032422 DOI: 10.1074/Jbc.M115.638700  1
2015 Parker EJ. The molecular basis for the substrate specificity of protein tyrosine phosphatase PTPN3. Structure (London, England : 1993). 23: 608-9. PMID 25862931 DOI: 10.1016/J.Str.2015.03.005  1
2015 Murianni A, Zanoli O, Parker EJ. Evaluation of pipe-soil interaction in liquefied soil Frontiers in Offshore Geotechnics Iii - Proceedings of the 3rd International Symposium On Frontiers in Offshore Geotechnics, Isfog 2015. 429-434.  1
2014 Lang EJ, Cross PJ, Mittelstädt G, Jameson GB, Parker EJ. Allosteric ACTion: the varied ACT domains regulating enzymes of amino-acid metabolism. Current Opinion in Structural Biology. 29: 102-11. PMID 25543886 DOI: 10.1016/J.Sbi.2014.10.007  1
2014 Naismith JH, Parker EJ. Editorial overview: Catalysis and regulation: enzyme catalysis, biosynthetic pathways and regulation. Current Opinion in Structural Biology. 29: iv-v. PMID 25480465 DOI: 10.1016/J.Sbi.2014.11.004  1
2014 Jones K, Parker EJ, Jamieson LM. Access, literacy and behavioural correlates of poor self-rated oral health amongst an indigenous south Australian population. Community Dental Health. 31: 167-71. PMID 25300152 DOI: 10.1922/CDH_3316Jones05  1
2014 Ben J, Jamieson LM, Priest N, Parker EJ, Roberts-Thomson KF, Lawrence HP, Broughton J, Paradies Y. Experience of racism and tooth brushing among pregnant Aboriginal Australians: exploring psychosocial mediators. Community Dental Health. 31: 145-52. PMID 25300148 DOI: 10.1922/CDH_3298Ben08  1
2014 Heyes LC, Reichau S, Cross PJ, Jameson GB, Parker EJ. Structural analysis of substrate-mimicking inhibitors in complex with Neisseria meningitidis 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase - The importance of accommodating the active site water. Bioorganic Chemistry. 57: 242-50. PMID 25245459 DOI: 10.1016/J.Bioorg.2014.08.003  1
2014 Cotton TR, Joseph DD, Jiao W, Parker EJ. Probing the determinants of phosphorylated sugar-substrate binding for human sialic acid synthase. Biochimica Et Biophysica Acta. 1844: 2257-2264. PMID 25242570 DOI: 10.1016/J.Bbapap.2014.09.014  1
2014 Jamieson LM, Armfield JM, Parker EJ, Roberts-Thomson KF, Broughton J, Lawrence HP. Development and evaluation of the Stages of Change in Oral Health instrument. International Dental Journal. 64: 269-77. PMID 25131429 DOI: 10.1111/idj.12119  1
2014 Ben J, Paradies Y, Priest N, Parker EJ, Roberts-Thomson KF, Lawrence HP, Broughton J, Jamieson LM. Self-reported racism and experience of toothache among pregnant Aboriginal Australians: the role of perceived stress, sense of control, and social support. Journal of Public Health Dentistry. 74: 301-9. PMID 24989691 DOI: 10.1111/jphd.12059  1
2014 Cookson TV, Castell A, Bulloch EM, Evans GL, Short FL, Baker EN, Lott JS, Parker EJ. Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis. The Biochemical Journal. 461: 87-98. PMID 24712732 DOI: 10.1042/Bj20140209  1
2014 Jamieson LM, Parker EJ, Roberts-Thomson KF, Lawrence HP, Broughton J. Self-efficacy and self-rated oral health among pregnant aboriginal Australian women. Bmc Oral Health. 14: 29. PMID 24690235 DOI: 10.1186/1472-6831-14-29  1
2014 Joseph DD, Jiao W, Kessans SA, Parker EJ. Substrate-mediated control of the conformation of an ancillary domain delivers a competent catalytic site for N-acetylneuraminic acid synthase. Proteins. 82: 2054-66. PMID 24633984 DOI: 10.1002/Prot.24558  1
2014 Hunter MF, Parker EJ. Modifying the determinants of α-ketoacid substrate selectivity in mycobacterium tuberculosis α-isopropylmalate synthase. Febs Letters. 588: 1603-7. PMID 24613923 DOI: 10.1016/J.Febslet.2014.02.053  1
2014 Nazmi AR, Schofield LR, Dobson RC, Jameson GB, Parker EJ. Destabilization of the homotetrameric assembly of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from the hyperthermophile Pyrococcus furiosus enhances enzymatic activity. Journal of Molecular Biology. 426: 656-73. PMID 24239948 DOI: 10.1016/J.Jmb.2013.11.008  1
2014 Jamieson LM, Parker EJ, Broughton J, Lawrence HP, Armfield JM. Are Stage of Change constructs relevant for subjective oral health in a vulnerable population? Community Dental Health. 32: 111-116. DOI: 10.1922/CDH_3439Jamieson  1
2013 Hobbs JK, Jiao W, Easter AD, Parker EJ, Schipper LA, Arcus VL. Change in heat capacity for enzyme catalysis determines temperature dependence of enzyme catalyzed rates. Acs Chemical Biology. 8: 2388-93. PMID 24015933 DOI: 10.1021/Cb4005029  1
2013 Scott B, Young CA, Saikia S, McMillan LK, Monahan BJ, Koulman A, Astin J, Eaton CJ, Bryant A, Wrenn RE, Finch SC, Tapper BA, Parker EJ, Jameson GB. Deletion and gene expression analyses define the paxilline biosynthetic gene cluster in Penicillium paxilli. Toxins. 5: 1422-46. PMID 23949005 DOI: 10.3390/Toxins5081422  1
2013 Cross PJ, Parker EJ. Allosteric inhibitor specificity of Thermotoga maritima 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase. Febs Letters. 587: 3063-8. PMID 23916814 DOI: 10.1016/J.Febslet.2013.07.044  1
2013 Mittelstädt G, Negron L, Schofield LR, Marsh K, Parker EJ. Biochemical and structural characterisation of dehydroquinate synthase from the New Zealand kiwifruit Actinidia chinensis. Archives of Biochemistry and Biophysics. 537: 185-91. PMID 23916589 DOI: 10.1016/J.Abb.2013.07.022  1
2013 Cross PJ, Pietersma AL, Allison TM, Wilson-Coutts SM, Cochrane FC, Parker EJ. Neisseria meningitidis expresses a single 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase that is inhibited primarily by phenylalanine. Protein Science : a Publication of the Protein Society. 22: 1087-99. PMID 23754471 DOI: 10.1002/Pro.2293  1
2013 Allison TM, Cochrane FC, Jameson GB, Parker EJ. Examining the role of intersubunit contacts in catalysis by 3-deoxy-d-manno-octulosonate 8-phosphate synthase. Biochemistry. 52: 4676-86. PMID 23746359 DOI: 10.1021/Bi400521F  1
2013 Jamieson LM, Divaris K, Parker EJ, Lee JY. Oral health literacy comparisons between Indigenous Australians and American Indians. Community Dental Health. 30: 52-7. PMID 23550508 DOI: 10.1922/Cdh_3025Jamieson06  1
2013 Xiong X, Xu Z, Yang Z, Liu Y, Wang D, Dong M, Parker EJ, Zhu W. Key targets and relevant inhibitors for the drug discovery of tuberculosis. Current Drug Targets. 14: 676-99. PMID 23547780 DOI: 10.2174/1389450111314060009  1
2013 Joseph DD, Jiao W, Parker EJ. Arg314 is essential for catalysis by N-acetyl neuraminic acid synthase from Neisseria meningitidis. Biochemistry. 52: 2609-19. PMID 23534460 DOI: 10.1021/Bi400062C  1
2013 Huisman FH, Squire CJ, Parker EJ. Amino-acid substitutions at the domain interface affect substrate and allosteric inhibitor binding in α-isopropylmalate synthase from Mycobacterium tuberculosis. Biochemical and Biophysical Research Communications. 433: 249-54. PMID 23500460 DOI: 10.1016/J.Bbrc.2013.02.092  1
2013 Castell A, Short FL, Evans GL, Cookson TV, Bulloch EM, Joseph DD, Lee CE, Parker EJ, Baker EN, Lott JS. The substrate capture mechanism of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase provides a mode for inhibition. Biochemistry. 52: 1776-87. PMID 23363292 DOI: 10.1021/Bi301387M  1
2013 Cross PJ, Allison TM, Dobson RC, Jameson GB, Parker EJ. Engineering allosteric control to an unregulated enzyme by transfer of a regulatory domain. Proceedings of the National Academy of Sciences of the United States of America. 110: 2111-6. PMID 23345433 DOI: 10.1073/Pnas.1217923110  1
2013 Blackmore NJ, Reichau S, Jiao W, Hutton RD, Baker EN, Jameson GB, Parker EJ. Three sites and you are out: ternary synergistic allostery controls aromatic amino acid biosynthesis in Mycobacterium tuberculosis. Journal of Molecular Biology. 425: 1582-92. PMID 23274137 DOI: 10.1016/J.Jmb.2012.12.019  1
2013 Parker EJ, Ardoino F, Bughi S. Performance based seismic design of suction pile foundations Proceedings of the International Conference On Offshore Mechanics and Arctic Engineering - Omae. 6. DOI: 10.1115/OMAE2013-11465  1
2013 Reichau S, Parker EJ. Active site plasticity of a critical enzyme from Mycobacterium tuberculosis Rsc Advances. 3: 3209-3212. DOI: 10.1039/C3Ra00037K  1
2012 Parker EJ, Misan G, Chong A, Mills H, Roberts-Thomson K, Horowitz AM, Jamieson LM. An oral health literacy intervention for Indigenous adults in a rural setting in Australia. Bmc Public Health. 12: 461. PMID 22716205 DOI: 10.1186/1471-2458-12-461  1
2012 Jiao W, Parker EJ. Using a combination of computational and experimental techniques to understand the molecular basis for protein allostery. Advances in Protein Chemistry and Structural Biology. 87: 391-413. PMID 22607762 DOI: 10.1016/B978-0-12-398312-1.00013-5  1
2012 Parker EJ, Misan G, Shearer M, Richards L, Russell A, Mills H, Jamieson LM. Planning, implementing, and evaluating a program to address the oral health needs of aboriginal children in port augusta, australia. International Journal of Pediatrics. 2012: 496236. PMID 22577401 DOI: 10.1155/2012/496236  0.01
2012 Huisman FH, Koon N, Bulloch EM, Baker HM, Baker EN, Squire CJ, Parker EJ. Removal of the C-terminal regulatory domain of α-isopropylmalate synthase disrupts functional substrate binding. Biochemistry. 51: 2289-97. PMID 22352945 DOI: 10.1021/Bi201717J  1
2012 Harrison AN, Reichau S, Parker EJ. Synthesis and evaluation of tetrahedral intermediate mimic inhibitors of 3-deoxy-d-manno-octulosonate 8-phosphate synthase. Bioorganic & Medicinal Chemistry Letters. 22: 907-11. PMID 22204912 DOI: 10.1016/J.Bmcl.2011.12.025  1
2012 Jiao W, Hutton RD, Cross PJ, Jameson GB, Parker EJ. Dynamic cross-talk among remote binding sites: the molecular basis for unusual synergistic allostery. Journal of Molecular Biology. 415: 716-26. PMID 22154807 DOI: 10.1016/J.Jmb.2011.11.037  1
2012 Wilkinson EF, Parker EJ. Preface Nitrogen Use in U.S. Agriculture: Implications and Management. vii-viii.  1
2012 Wilkinson EF, Parker EJ. Nitrogen use in U.S. agriculture: Implications and management Nitrogen Use in U.S. Agriculture: Implications and Management. 1-122.  1
2012 Parker EJ, Ardoino F, Bughi S. Seismic performance of suction pile foundations - Practical solutions Proceedings of the International Offshore and Polar Engineering Conference. 674-680.  1
2011 Tran D, Pietersma AL, Schofield LR, Rost M, Jameson GB, Parker EJ. Investigating the role of the hydroxyl groups of substrate erythrose 4-phosphate in the reaction catalysed by the first enzyme of the shikimate pathway. Bioorganic & Medicinal Chemistry Letters. 21: 6838-41. PMID 21978677 DOI: 10.1016/J.Bmcl.2011.09.017  1
2011 Allison TM, Hutton RD, Jiao W, Gloyne BJ, Nimmo EB, Jameson GB, Parker EJ. An extended β7α7 substrate-binding loop is essential for efficient catalysis by 3-deoxy-D-manno-octulosonate 8-phosphate synthase. Biochemistry. 50: 9318-27. PMID 21942786 DOI: 10.1021/Bi201231E  1
2011 Parker EJ, Jamieson LM, Steffens MA, Cathro P, Logan RM. Self-reported oral health of a metropolitan homeless population in Australia: comparisons with population-level data. Australian Dental Journal. 56: 272-7. PMID 21884142 DOI: 10.1111/j.1834-7819.2011.01346.x  1
2011 Negron L, Patchett ML, Parker EJ. Expression, Purification, and Characterisation of Dehydroquinate Synthase from Pyrococcus furiosus. Enzyme Research. 2011: 134893. PMID 21603259 DOI: 10.4061/2011/134893  1
2011 Walker SR, Jiao W, Parker EJ. Synthesis and evaluation of dual site inhibitors of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase. Bioorganic & Medicinal Chemistry Letters. 21: 5092-7. PMID 21493065 DOI: 10.1016/J.Bmcl.2011.03.071  1
2011 Reichau S, Jiao W, Walker SR, Hutton RD, Baker EN, Parker EJ. Potent inhibitors of a shikimate pathway enzyme from Mycobacterium tuberculosis: combining mechanism- and modeling-based design. The Journal of Biological Chemistry. 286: 16197-207. PMID 21454647 DOI: 10.1074/Jbc.M110.211649  1
2011 Allison TM, Hutton RD, Cochrane FC, Yeoman JA, Jameson GB, Parker EJ. Targeting the role of a key conserved motif for substrate selection and catalysis by 3-deoxy-D-manno-octulosonate 8-phosphate synthase. Biochemistry. 50: 3686-95. PMID 21438567 DOI: 10.1021/Bi200251F  1
2011 Negron L, Parker EJ. Fluorinated substrates result in variable leakage of a reaction intermediate during catalysis by dehydroquinate synthase. Organic & Biomolecular Chemistry. 9: 2861-7. PMID 21387027 DOI: 10.1039/C0Ob01141J  1
2011 Cross PJ, Dobson RC, Patchett ML, Parker EJ. Tyrosine latching of a regulatory gate affords allosteric control of aromatic amino acid biosynthesis. The Journal of Biological Chemistry. 286: 10216-24. PMID 21282100 DOI: 10.1074/Jbc.M110.209924  1
2011 Johnson WJ, Zolezzi F, Nicholls J, Parker EJ, Morgante E. Geohazard interpretation of the Cagliari slope (Southern Sardinia, Italy) Geotechnical Special Publication. 820-828. DOI: 10.1061/41183(418)86  1
2011 Parker EJ, Pratt AJ. Amino Acid Biosynthesis Amino Acids, Peptides and Proteins in Organic Chemistry. 3: 1-82. DOI: 10.1002/9783527631803.ch1  1
2010 Parker EJ, Jamieson LM, Broughton J, Albino J, Lawrence HP, Roberts-Thomson K. The oral health of Indigenous children: a review of four nations. Journal of Paediatrics and Child Health. 46: 483-6. PMID 20854317 DOI: 10.1111/j.1440-1754.2010.01847.x  1
2010 Mejia GC, Parker EJ, Jamieson LM. An introduction to oral health inequalities among Indigenous and non-Indigenous populations. International Dental Journal. 60: 212-5. PMID 20718305 DOI: 10.1922/IDJ-2565Jamieson04  1
2010 Webby CJ, Jiao W, Hutton RD, Blackmore NJ, Baker HM, Baker EN, Jameson GB, Parker EJ. Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis. The Journal of Biological Chemistry. 285: 30567-76. PMID 20667835 DOI: 10.1074/Jbc.M110.111856  1
2010 Jiao W, McDonald DQ, Coxon JM, Parker EJ. Molecular modeling studies of peptide inhibitors highlight the importance of conformational prearrangement for inhibition of calpain. Biochemistry. 49: 5533-9. PMID 20499928 DOI: 10.1021/Bi100048Y  1
2010 Allison TM, Yeoman JA, Hutton RD, Cochrane FC, Jameson GB, Parker EJ. Specificity and mutational analysis of the metal-dependent 3-deoxy-D-manno-octulosonate 8-phosphate synthase from Acidithiobacillus ferrooxidans. Biochimica Et Biophysica Acta. 1804: 1526-36. PMID 20406700 DOI: 10.1016/J.Bbapap.2010.04.005  1
2010 Parker EJ, Jamieson LM. Associations between indigenous Australian oral health literacy and self-reported oral health outcomes. Bmc Oral Health. 10: 3. PMID 20346124 DOI: 10.1186/1472-6831-10-3  1
2010 Huisman FH, Hunter MF, Devenish SR, Gerrard JA, Parker EJ. The C-terminal regulatory domain is required for catalysis by Neisseria meningitidis alpha-isopropylmalate synthase. Biochemical and Biophysical Research Communications. 393: 168-73. PMID 20117081 DOI: 10.1016/J.Bbrc.2010.01.114  1
2009 Cochrane FC, Cookson TV, Jameson GB, Parker EJ. Reversing evolution: re-establishing obligate metal ion dependence in a metal-independent KDO8P synthase. Journal of Molecular Biology. 390: 646-61. PMID 19447118 DOI: 10.1016/J.Jmb.2009.05.014  1
2009 Devenish SR, Huisman FH, Parker EJ, Hadfield AT, Gerrard JA. Cloning and characterisation of dihydrodipicolinate synthase from the pathogen Neisseria meningitidis. Biochimica Et Biophysica Acta. 1794: 1168-74. PMID 19236959 DOI: 10.1016/J.Bbapap.2009.02.003  1
2009 Walker SR, Cumming H, Parker EJ. Substrate and reaction intermediate mimics as inhibitors of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase Organic and Biomolecular Chemistry. 7: 3031-3035. DOI: 10.1039/B909241B  1
2008 Ahn M, Cochrane FC, Patchett ML, Parker EJ. Arabinose 5-phosphate analogues as mechanistic probes for Neisseria meningitidis 3-deoxy-D-manno-octulosonate 8-phosphate synthase. Bioorganic & Medicinal Chemistry. 16: 9830-6. PMID 18930408 DOI: 10.1016/J.Bmc.2008.09.056  1
2008 Saikia S, Nicholson MJ, Young C, Parker EJ, Scott B. The genetic basis for indole-diterpene chemical diversity in filamentous fungi. Mycological Research. 112: 184-99. PMID 18262778 DOI: 10.1016/J.Mycres.2007.06.015  1
2008 Jamieson LM, Parker EJ, Richards L. Using qualitative methodology to inform an Indigenous-owned oral health promotion initiative in Australia. Health Promotion International. 23: 52-9. PMID 18056724 DOI: 10.1093/heapro/dam042  1
2007 Sheng H, Parker EJ, Bullimore MA. An evaluation of the ConfoScan3 for corneal endothelial morphology analysis. Optometry and Vision Science : Official Publication of the American Academy of Optometry. 84: 888-95. PMID 17873775 DOI: 10.1097/Opx.0B013E3181559C01  0.01
2007 Parker EJ, Jamieson LM. Oral health comparisons between children attending an Aboriginal health service and a Government school dental service in a regional location. Rural and Remote Health. 7: 625. PMID 17474830  1
2007 Saikia S, Parker EJ, Koulman A, Scott B. Defining paxilline biosynthesis in Penicillium paxilli: functional characterization of two cytochrome P450 monooxygenases. The Journal of Biological Chemistry. 282: 16829-37. PMID 17428785 DOI: 10.1074/Jbc.M701626200  1
2007 Jamieson LM, Parker EJ, Armfield JM. Indigenous child oral health at a regional and state level. Journal of Paediatrics and Child Health. 43: 117-21. PMID 17316183 DOI: 10.1111/j.1440-1754.2007.01029.x  1
2006 Walker SR, Parker EJ. Synthesis and evaluation of a mechanism-based inhibitor of a 3-deoxy-D-arabino heptulosonate 7-phosphate synthase. Bioorganic & Medicinal Chemistry Letters. 16: 2951-4. PMID 16563755 DOI: 10.1016/J.Bmcl.2006.02.073  1
2006 Saikia S, Parker EJ, Koulman A, Scott B. Four gene products are required for the fungal synthesis of the indole-diterpene, paspaline. Febs Letters. 580: 1625-30. PMID 16494875 DOI: 10.1016/J.Febslet.2006.02.008  1
2006 Parker E, Bullimore MA. Butterworth Heinemann???s Review Questions for the NBEO Examination: Part One Optometry and Vision Science. 83: 865. DOI: 10.1097/01.Opx.0000250500.61350.C0  0.01
2005 Webby CJ, Lott JS, Baker HM, Baker EN, Parker EJ. Crystallization and preliminary X-ray crystallographic analysis of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Mycobacterium tuberculosis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 403-6. PMID 16511053 DOI: 10.1107/S1744309105007931  1
2005 Webby CJ, Baker HM, Lott JS, Baker EN, Parker EJ. The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis reveals a common catalytic scaffold and ancestry for type I and type II enzymes. Journal of Molecular Biology. 354: 927-39. PMID 16288916 DOI: 10.1016/J.Jmb.2005.09.093  1
2005 Ahn M, Pietersma AL, Schofield LR, Parker EJ. Mechanistic divergence of two closely related aldol-like enzyme-catalysed reactions. Organic & Biomolecular Chemistry. 3: 4046-9. PMID 16267580 DOI: 10.1039/B511661A  1
2005 Schofield LR, Anderson BF, Patchett ML, Norris GE, Jameson GB, Parker EJ. Substrate ambiguity and crystal structure of Pyrococcus furiosus 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase: an ancestral 3-deoxyald-2-ulosonate-phosphate synthase? Biochemistry. 44: 11950-62. PMID 16142893 DOI: 10.1021/Bi050577Z  1
2005 Tanaka A, Tapper BA, Popay A, Parker EJ, Scott B. A symbiosis expressed non-ribosomal peptide synthetase from a mutualistic fungal endophyte of perennial ryegrass confers protection to the symbiotum from insect herbivory. Molecular Microbiology. 57: 1036-50. PMID 16091042 DOI: 10.1111/J.1365-2958.2005.04747.X  1
2005 Parker EJ, Misan G, Richards LC, Russell A. Planning and implementing the first stage of an oral health program for the Pika Wiya Health Service Incorporated Aboriginal community in Port Augusta, South Australia. Rural and Remote Health. 5: 254. PMID 15885023  1
2005 Webby CJ, Patchett ML, Parker EJ. Characterization of a recombinant type II 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Helicobacter pylori. The Biochemical Journal. 390: 223-30. PMID 15853768 DOI: 10.1042/Bj20050259  1
2005 Williamson RM, Pietersma AL, Jameson GB, Parker EJ. Stereospecific deuteration of 2-deoxyerythrose 4-phosphate using 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase. Bioorganic & Medicinal Chemistry Letters. 15: 2339-42. PMID 15837321 DOI: 10.1016/J.Bmcl.2005.02.080  1
2004 Bulloch EM, Jones MA, Parker EJ, Osborne AP, Stephens E, Davies GM, Coggins JR, Abell C. Identification of 4-amino-4-deoxychorismate synthase as the molecular target for the antimicrobial action of (6s)-6-fluoroshikimate. Journal of the American Chemical Society. 126: 9912-3. PMID 15303852 DOI: 10.1021/Ja048312F  1
2004 Schofield LR, Patchett ML, Parker EJ. Expression, purification, and characterization of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Pyrococcus furiosus. Protein Expression and Purification. 34: 17-27. PMID 14766297 DOI: 10.1016/J.Pep.2003.11.008  1
2003 Frederickson M, Parker EJ, Coggins JR, Abell C. Enzymic synthesis of 3-[3- 13C]dehydroquinic acid. Organic & Biomolecular Chemistry. 1: 3271-3. PMID 14584789 DOI: 10.1039/B309666A  1
2003 McMillan LK, Carr RL, Young CA, Astin JW, Lowe RG, Parker EJ, Jameson GB, Finch SC, Miles CO, McManus OB, Schmalhofer WA, Garcia ML, Kaczorowski GJ, Goetz M, Tkacz JS, et al. Molecular analysis of two cytochrome P450 monooxygenase genes required for paxilline biosynthesis in Penicillium paxilli, and effects of paxilline intermediates on mammalian maxi-K ion channels. Molecular Genetics and Genomics : Mgg. 270: 9-23. PMID 12884010 DOI: 10.1007/S00438-003-0887-2  1
2003 Frederickson M, Parker EJ, Coggins JR, Abell C. Enzymic synthesis of 3-[3-13C]dehydroquinic acid Organic and Biomolecular Chemistry. 1: 3271-3273. DOI: 10.1039/b309666a  1
2001 Parker EJ, Bulloch EM, Jameson GB, Abell C. Substrate deactivation of phenylalanine-sensitive 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase by erythrose 4-phosphate. Biochemistry. 40: 14821-8. PMID 11732901 DOI: 10.1021/Bi010928J  1
2000 Parker EJ, González Bello C, Coggins JR, Hawkins AR, Abell C. Mechanistic studies on type I and type II dehydroquinase with (6R)- and (6S)-6-fluoro-3-dehydroquinic acids. Bioorganic & Medicinal Chemistry Letters. 10: 231-4. PMID 10698442 DOI: 10.1016/S0960-894X(99)00660-5  1
1999 Frederickson M, Parker EJ, Hawkins AR, Coggins JR, Abell C. Selective Inhibition of Type II Dehydroquinases. The Journal of Organic Chemistry. 64: 2612-2613. PMID 11674325 DOI: 10.1021/Jo990004Q  1
1998 Parker EJ, Botting CH, Webster A, Hay RT. Adenovirus DNA polymerase: domain organisation and interaction with preterminal protein. Nucleic Acids Research. 26: 1240-7. PMID 9469832  0.01
1997 Parker EJ, Coggins JR, Abell C. Derailing Dehydroquinate Synthase by Introducing a Stabilizing Stereoelectronic Effect in a Reaction Intermediate. The Journal of Organic Chemistry. 62: 8582-8585. PMID 11672011 DOI: 10.1021/Jo9713060  1
1995 Li J, Chang HW, Lai E, Parker EJ, Vogt PK. The oncogene qin codes for a transcriptional repressor. Cancer Research. 55: 5540-4. PMID 7585630  0.01
1995 Duggan PJ, Parker E, Coggins J, Abell C. Enzymatic synthesis of (6R)- and (6S)-fluoroshikimic acids Bioorganic and Medicinal Chemistry Letters. 5: 2347-2352. DOI: 10.1016/0960-894X(95)00405-I  1
1993 Schuur ER, Parker EJ, Vogt PK. Chimeras of herpes simplex viral VP16 and jun are oncogenic. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 4: 761-8. PMID 8241024  0.01
1981 Parker EJ. Reducing ventilation in patient rooms for energy conservation. Dimensions in Health Service. 58: 22-3. PMID 7239039  0.01
1980 Parker EJ, Schrieber V. Repeat prescribing--a study in one practice. The Journal of the Royal College of General Practitioners. 30: 603-6. PMID 6779000  0.01
1972 Baker R, Parker EJ. Femoro-femoral cross-over grafts. A report of 7 cases. The British Journal of Surgery. 59: 701-4. PMID 4115991  0.01
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