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Jeff Holder, Ph.D. - Publications

Affiliations: 
2014 Chemistry California Institute of Technology, Pasadena, CA 
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30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Holder JC, Shockley SE, Wiesenfeldt MP, Shimizu H, Stoltz BM. Preparation of ()--ButylPyOx and Palladium-catalyzed Asymmetric Conjugate Addition of Arylboronic Acids. Organic Syntheses; An Annual Publication of Satisfactory Methods For the Preparation of Organic Chemicals. 92. PMID 31057190 DOI: 10.1002/0471264229.Os092.19  0.685
2016 Sison-Young RL, Lauschke VM, Johann E, Alexandre E, Antherieu S, Aerts H, Gerets HH, Labbe G, Hoët D, Dorau M, Schofield CA, Lovatt CA, Holder JC, Stahl SH, Richert L, et al. A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity. Archives of Toxicology. PMID 27344343 DOI: 10.1007/s00204-016-1745-4  0.58
2016 Shindo A, Maki T, Mandeville ET, Liang AC, Egawa N, Itoh K, Itoh N, Borlongan M, Holder JC, Chuang TT, McNeish JD, Tomimoto H, Lok J, Lo EH, Arai K. Astrocyte-Derived Pentraxin 3 Supports Blood-Brain Barrier Integrity Under Acute Phase of Stroke. Stroke; a Journal of Cerebral Circulation. PMID 26965847 DOI: 10.1161/STROKEAHA.115.012133  0.543
2016 Liang AC, Mandeville ET, Maki T, Shindo A, Som AT, Egawa N, Itoh K, Chuang TT, McNeish JD, Holder JC, Lok J, Lo EH, Arai K. Effects of aging on neural stem/progenitor cells and oligodendrocyte precursor cells after focal cerebral ischemia in spontaneously hypertensive rats. Cell Transplantation. PMID 26811151 DOI: 10.3727/096368916X690557  0.566
2015 Shockley SE, Holder JC, Stoltz BM. Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to α,β-Unsaturated Cyclic Electrophiles. Organic Process Research & Development. 19: 974-981. PMID 27293370 DOI: 10.1021/Acs.Oprd.5B00169  0.698
2015 Holder JC, Goodman ED, Kikushima K, Gatti M, Marziale AN, Stoltz BM. Synthesis of diverse β-quaternary ketones via palladium-catalyzed asymmetric conjugate addition of arylboronic acids to cyclic enones. Tetrahedron. 71: 5781-5792. PMID 26461082 DOI: 10.1016/J.Tet.2014.11.048  0.693
2015 Koh SH, Liang AC, Takahashi Y, Maki T, Shindo A, Osumi N, Zhao J, Lin H, Holder JC, Chuang TT, McNeish JD, Arai K, Lo EH. Differential Effects of Isoxazole-9 on Neural Stem/Progenitor Cells, Oligodendrocyte Precursor Cells, and Endothelial Progenitor Cells. Plos One. 10: e0138724. PMID 26407349 DOI: 10.1371/Journal.Pone.0138724  0.571
2015 Lin H, Fang H, Wang J, Meng Q, Dai X, Wu S, Luo J, Pu D, Chen L, Minick D, Arai K, Mandeville ET, Lo E, Holder JC, Chuang TT, et al. Discovery of a novel 2,3,11,11a-tetrahydro-1H-pyrazino[1,2-b]isoquinoline-1,4(6H)-dione series promoting neurogenesis of human neural progenitor cells. Bioorganic & Medicinal Chemistry Letters. PMID 26142946 DOI: 10.1016/J.Bmcl.2015.05.084  0.58
2015 Boeser CL, Holder JC, Taylor BL, Houk KN, Stoltz BM, Zare RN. Mechanistic analysis of an asymmetric palladium-catalyzed conjugate addition of arylboronic acids to β-substituted cyclic enones. Chemical Science (Royal Society of Chemistry : 2010). 6: 1917-1922. PMID 25729560 DOI: 10.1039/C4Sc03337J  0.683
2015 Shockley SE, Holder JC, Stoltz BM. Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to α,β-Unsaturated Cyclic Electrophiles Organic Process Research and Development. 19: 974-981. DOI: 10.1021/acs.oprd.5b00169  0.679
2014 Shockley SE, Holder JC, Stoltz BM. A catalytic, enantioselective formal synthesis of (+)-dichroanone and (+)-taiwaniaquinone H. Organic Letters. 16: 6362-5. PMID 25489925 DOI: 10.1021/Ol5031537  0.659
2014 Kim JH, Bothe JR, Frederick RO, Holder JC, Markley JL. Role of IscX in iron-sulfur cluster biogenesis in Escherichia coli. Journal of the American Chemical Society. 136: 7933-42. PMID 24810328 DOI: 10.1021/Ja501260H  0.555
2014 Hailey JR, Nold JB, Brown RH, Cullen JM, Holder JC, Jordan HL, Ennulat D, Miller RT. Biliary proliferative lesions in the Sprague-Dawley rat: adverse/non-adverse. Toxicologic Pathology. 42: 844-54. PMID 23960163 DOI: 10.1177/0192623313499976  0.56
2014 Holder JC, Goodman ED, Kikushima K, Gatti M, Marziale AN, Stoltz BM. Synthesis of diverse β-quaternary ketones via palladium-catalyzed asymmetric conjugate addition of arylboronic acids to cyclic enones Tetrahedron. DOI: 10.1016/j.tet.2014.11.048  0.695
2013 Shimizu H, Holder JC, Stoltz BM. A scalable synthesis of the (S)-4-(tert-butyl)-2-(pyridin-2-yl)-4,5-dihydrooxazole ((S)-t-BuPyOx) ligand. Beilstein Journal of Organic Chemistry. 9: 1637-42. PMID 24062823 DOI: 10.3762/Bjoc.9.187  0.702
2013 Holder JC, Zou L, Marziale AN, Liu P, Lan Y, Gatti M, Kikushima K, Houk KN, Stoltz BM. Mechanism and enantioselectivity in palladium-catalyzed conjugate addition of arylboronic acids to β-substituted cyclic enones: insights from computation and experiment. Journal of the American Chemical Society. 135: 14996-5007. PMID 24028424 DOI: 10.1021/Ja401713G  0.691
2013 Holder JC, Marziale AN, Gatti M, Mao B, Stoltz BM. Palladium-catalyzed asymmetric conjugate addition of arylboronic acids to heterocyclic acceptors. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 74-7. PMID 23208950 DOI: 10.1002/Chem.201203643  0.684
2012 Solanky BS, Sanchez-Canon GJ, Cobbold JF, Taylor-Robinson SD, Bell JD, Scudamore CL, Ross E, Holder JC, So PW, Cox IJ. Metabolic profiling of the rat liver after chronic ingestion of alpha-naphthylisothiocyanate using in vivo and ex vivo magnetic resonance spectroscopy. Toxicological Sciences : An Official Journal of the Society of Toxicology. 126: 306-16. PMID 22262563 DOI: 10.1093/toxsci/kfs019  0.566
2012 Alavijeh MS, Brown KA, Holder JC, Ratcliffe AJ. The importance of (BIO)pharmaceutical properties in successful drug design: Highlights from the Society of Medicines Research Symposium, held on October 4th, 2012 - National Heart and Lung Institute, Kensington, London Drugs of the Future. 37: 879-883. DOI: 10.1358/dof.2012.037.012.1899643  0.534
2011 Kikushima K, Holder JC, Gatti M, Stoltz BM. Palladium-catalyzed asymmetric conjugate addition of arylboronic acids to five-, six-, and seven-membered β-substituted cyclic enones: enantioselective construction of all-carbon quaternary stereocenters. Journal of the American Chemical Society. 133: 6902-5. PMID 21495647 DOI: 10.1021/Ja200664X  0.687
2011 Komoroski RA, Holder JC, Pappas AA, Finkbeiner AE. 31P NMR of phospholipid metabolites in prostate cancer and benign prostatic hyperplasia. Magnetic Resonance in Medicine. 65: 911-3. PMID 20967792 DOI: 10.1002/mrm.22677  0.546
2009 Varley CL, Bacon EJ, Holder JC, Southgate J. FOXA1 and IRF-1 intermediary transcriptional regulators of PPARgamma-induced urothelial cytodifferentiation. Cell Death and Differentiation. 16: 103-14. PMID 18688264 DOI: 10.1038/cdd.2008.116  0.579
2008 MacLaine NJ, Wood MD, Holder JC, Rees RW, Southgate J. Sensitivity of normal, paramalignant, and malignant human urothelial cells to inhibitors of the epidermal growth factor receptor signaling pathway. Molecular Cancer Research : McR. 6: 53-63. PMID 18234962 DOI: 10.1158/1541-7786.MCR-07-0134  0.58
2005 Delaney J, Hodson MP, Thakkar H, Connor SC, Sweatman BC, Kenny SP, McGill PJ, Holder JC, Hutton KA, Haselden JN, Waterfield CJ. Tryptophan-NAD+ pathway metabolites as putative biomarkers and predictors of peroxisome proliferation. Archives of Toxicology. 79: 208-23. PMID 15838709 DOI: 10.1007/s00204-004-0625-5  0.585
2005 Macanas-Pirard P, Yaacob NS, Lee PC, Holder JC, Hinton RH, Kass GE. Glycogen synthase kinase-3 mediates acetaminophen-induced apoptosis in human hepatoma cells. The Journal of Pharmacology and Experimental Therapeutics. 313: 780-9. PMID 15665138 DOI: 10.1124/jpet.104.081364  0.567
2004 Pearce NJ, Arch JR, Clapham JC, Coghlan MP, Corcoran SL, Lister CA, Llano A, Moore GB, Murphy GJ, Smith SA, Taylor CM, Yates JW, Morrison AD, Harper AJ, Roxbee-Cox L, ... Holder JC, et al. Development of glucose intolerance in male transgenic mice overexpressing human glycogen synthase kinase-3beta on a muscle-specific promoter. Metabolism: Clinical and Experimental. 53: 1322-30. PMID 15375789 DOI: 10.1016/J.Metabol.2004.05.008  0.572
2004 Schmuth M, Haqq CM, Cairns WJ, Holder JC, Dorsam S, Chang S, Lau P, Fowler AJ, Chuang G, Moser AH, Brown BE, Mao-Qiang M, Uchida Y, Schoonjans K, Auwerx J, et al. Peroxisome proliferator-activated receptor (PPAR)-beta/delta stimulates differentiation and lipid accumulation in keratinocytes. The Journal of Investigative Dermatology. 122: 971-83. PMID 15102088 DOI: 10.1111/J.0022-202X.2004.22412.X  0.569
2003 Patel NG, Holder JC, Smith SA, Kumar S, Eggo MC. Differential regulation of lipogenesis and leptin production by independent signaling pathways and rosiglitazone during human adipocyte differentiation. Diabetes. 52: 43-50. PMID 12502492 DOI: 10.2337/Diabetes.52.1.43  0.582
2003 Brown AJ, Goldsworthy SM, Barnes AA, Eilert MM, Tcheang L, Daniels D, Muir AI, Wigglesworth MJ, Kinghorn I, Fraser NJ, Pike NB, Strum JC, Steplewski KM, Murdock PR, Holder JC, et al. The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. The Journal of Biological Chemistry. 278: 11312-9. PMID 12496283 DOI: 10.1074/jbc.M211609200  0.595
2002 McTernan PG, Harte AL, Anderson LA, Green A, Smith SA, Holder JC, Barnett AH, Eggo MC, Kumar S. Insulin and rosiglitazone regulation of lipolysis and lipogenesis in human adipose tissue in vitro. Diabetes. 51: 1493-8. PMID 11978647 DOI: 10.2337/DIABETES.51.5.1493  0.557
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