Year |
Citation |
Score |
2023 |
Bao J, Nick SJ, Lanin AS, Iragorri Molinero N, Sera BJ, Njardarson JT. Stereoselective Synthesis of Conjugated Di- and Trienamides via a Dienolate Enabled Anionic Cascade. The Journal of Organic Chemistry. PMID 38048698 DOI: 10.1021/acs.joc.3c02327 |
0.417 |
|
2023 |
Groch JR, Lauta NR, Njardarson JT. One Step Selective Counterion Dependent Formation of Conjugated Chiral N-Sulfinylimines from Aldehydes. Organic Letters. 25: 395-399. PMID 36603180 DOI: 10.1021/acs.orglett.2c04102 |
0.376 |
|
2022 |
Qureshi MH, Njardarson JT. Anionic Amino-Cope Rearrangement Cascade Synthesis of 2,4-Substituted Benzoate Esters from Acyclic Building Blocks. Organic Letters. 24: 7978-7982. PMID 36268999 DOI: 10.1021/acs.orglett.2c03134 |
0.345 |
|
2021 |
Delost MD, Njardarson JT. Mild Darzens Annulations for the Assembly of Trifluoromethylthiolated (SCF) Aziridine and Cyclopropane Structures. Organic Letters. 23: 6121-6125. PMID 34292753 DOI: 10.1021/acs.orglett.1c02204 |
0.42 |
|
2021 |
Scott KA, Groch JR, Chogii I, Delost MD, Das P, Njardarson JT. Dienolate Annulation Approach for Assembly of Densely Substituted Aromatic Architectures. The Journal of Organic Chemistry. PMID 34283591 DOI: 10.1021/acs.joc.1c01211 |
0.42 |
|
2021 |
Scott KA, Groch JR, Chogii I, Delost MD, Das P, Njardarson JT. Dienolate Annulation Approach for Assembly of Densely Substituted Aromatic Architectures. The Journal of Organic Chemistry. PMID 34283591 DOI: 10.1021/acs.joc.1c01211 |
0.42 |
|
2021 |
Lauta NR, Williams RE, Smith DT, Kumirov VK, Njardarson JT. Oxidative Route to Indoles via Intramolecular Amino-Hydroxylation of -Allenyl Anilines. The Journal of Organic Chemistry. PMID 34282910 DOI: 10.1021/acs.joc.1c01379 |
0.342 |
|
2021 |
Das P, Delost MD, Qureshi MH, Bao J, Fell JS, Houk KN, Njardarson JT. Dramatic Effect of γ-Heteroatom Dienolate Substituents on Counterion Assisted Asymmetric Anionic Amino-Cope Reaction Cascades. Journal of the American Chemical Society. PMID 33844522 DOI: 10.1021/jacs.1c00745 |
0.347 |
|
2020 |
Delost MD, Njardarson JT. Strategic Vinyl Sulfone Nucleophile β-Substitution Significantly Impacts Selectivity in Vinylogous Darzens and Aza-Darzens Reactions. Organic Letters. PMID 32822201 DOI: 10.1021/Acs.Orglett.0C02448 |
0.385 |
|
2019 |
Chogii I, Das P, Njardarson JT. Efforts Toward a Unified Kainoid Family Synthesis Approach: Unexpected Sulfinamide‐Directed Conjugate Addition Results Asian Journal of Organic Chemistry. 8: 1041-1044. DOI: 10.1002/Ajoc.201800728 |
0.409 |
|
2018 |
Chogii I, Das P, Delost MD, Crawford MN, Njardarson JT. Asymmetric Vinylogous Aza-Darzens Approach to Vinyl Aziridines. Organic Letters. PMID 30052042 DOI: 10.1021/Acs.Orglett.8B02074 |
0.483 |
|
2018 |
Delost MD, Smith DT, Anderson BJ, Njardarson JT. From Oxiranes to Oligomers: Architectures of US FDA Approved Pharmaceuticals Containing Oxygen Heterocycles. Journal of Medicinal Chemistry. PMID 30024747 DOI: 10.1021/Acs.Jmedchem.8B00876 |
0.305 |
|
2018 |
Chogii I, Das P, Fell JS, Scott KA, Crawford MN, Houk KN, Njardarson JT. Correction to "New Class of Anion-Accelerated Amino-Cope Rearrangements as Gateway to Diverse Chiral Structures". Journal of the American Chemical Society. PMID 30010325 DOI: 10.1021/Jacs.8B06895 |
0.307 |
|
2018 |
Smith BR, Njardarson JT. Correction to [2.2.2]- to [3.2.1]-Bicycle Skeletal Rearrangement Approach to the Gibberellin Family of Natural Products. Organic Letters. PMID 30004713 DOI: 10.1021/Acs.Orglett.8B02053 |
0.36 |
|
2018 |
Smith BR, Njardarson JT. Review of synthetic approaches toward maoecrystal V. Organic & Biomolecular Chemistry. PMID 29775191 DOI: 10.1039/C8Ob00909K |
0.338 |
|
2018 |
Smith BR, Njardarson JT. [2.2.2]- to [3.2.1]-Bicycle Skeletal Rearrangement Approach to the Gibberellin Family of Natural Products. Organic Letters. PMID 29722990 DOI: 10.1021/Acs.Orglett.8B01031 |
0.448 |
|
2017 |
Leung JC, Bedermann AA, Njardarson JT, Spiegel DA, Murphy GK, Hama N, Twenter BM, Dong P, Shirahata T, McDonald IM, Inoue M, Taniguchi N, McMahon TC, Schneider CM, Tao N, et al. Total Synthesis of (±)-Phomoidride D. Angewandte Chemie (International Ed. in English). PMID 29286556 DOI: 10.1002/Anie.201712369 |
0.768 |
|
2017 |
Smith BR, Njardarson JT. Double-Diels-Alder Approach to Maoecrystal V. Unexpected C-C Bond-Forming Fragmentations of the [2.2.2]-Bicyclic Core. Organic Letters. PMID 28910114 DOI: 10.1021/Acs.Orglett.7B02606 |
0.406 |
|
2017 |
Chogii I, Das P, Fell JS, Scott KA, Crawford MN, Houk KN, Njardarson JT. New Class of Anion-Accelerated Amino-Cope Rearrangements as Gateway to Diverse Chiral Structures. Journal of the American Chemical Society. PMID 28885835 DOI: 10.1021/Jacs.7B07319 |
0.411 |
|
2017 |
Smith DT, Vitaku E, Njardarson JT. Dearomatization Approach to 2-Trifluoromethylated Benzofuran and Dihydrobenzofuran Products. Organic Letters. PMID 28598632 DOI: 10.1021/Acs.Orglett.7B01479 |
0.426 |
|
2016 |
Vitaku E, Smith DT, Njardarson JT. Metal-Free Synthesis of Fluorinated Indoles Enabled by Oxidative Dearomatization. Angewandte Chemie (International Ed. in English). PMID 26748561 DOI: 10.1002/Anie.201511149 |
0.469 |
|
2016 |
Vitaku E, Njardarson JT. A Mildmeta-Selective C-H Alkylation of Catechol Mono-Ethers European Journal of Organic Chemistry. 2016: 3679-3683. DOI: 10.1002/Ejoc.201600760 |
0.375 |
|
2016 |
Das P, Njardarson JT. Anionic Cascade Routes to Sulfur and Nitrogen Heterocycles Originating from Thio- and Aminophosphate Precursors European Journal of Organic Chemistry. 2016: 4249-4259. DOI: 10.1002/Ejoc.201600312 |
0.406 |
|
2015 |
Chogii I, Njardarson JT. Asymmetric [3+2] Annulation Approach to 3-Pyrrolines: Concise Total Syntheses of (-)-Supinidine, (-)-Isoretronecanol, and (+)-Elacomine. Angewandte Chemie (International Ed. in English). 54: 13706-10. PMID 26447827 DOI: 10.1002/Anie.201506559 |
0.52 |
|
2015 |
Das P, Njardarson JT. Synthesis of 1,2,3,6-Tetrahydropyridines via Aminophosphate Enabled Anionic Cascade and Acid Catalyzed Cyclization Approaches. Organic Letters. 17: 4030-3. PMID 26247299 DOI: 10.1021/Acs.Orglett.5B01937 |
0.441 |
|
2015 |
Vitaku E, Njardarson JT. Formation of Fused Aromatic Architectures via an Oxidative Dearomatization - Radical Cyclization Rearomatization Approach. Tetrahedron Letters. 56: 3550-3552. PMID 26236054 DOI: 10.1016/J.Tetlet.2015.01.110 |
0.456 |
|
2015 |
Draghici C, Njardarson JT. Synthetic Approaches and Total Syntheses of Vinigrol, a Unique Diterpenoid. Tetrahedron. 71: 3775-3793. PMID 26034329 DOI: 10.1016/J.Tet.2015.04.073 |
0.393 |
|
2015 |
Draghici C, Njardarson JT. The Realization of an Oxidative Dearomatization-Intramolecular Diels-Alder Route to Vinigrol Strategies and Tactics in Organic Synthesis. 11: 335-376. DOI: 10.1016/B978-0-08-100023-6.00011-7 |
0.447 |
|
2014 |
Vitaku E, Smith DT, Njardarson JT. Analysis of the structural diversity, substitution patterns, and frequency of nitrogen heterocycles among U.S. FDA approved pharmaceuticals. Journal of Medicinal Chemistry. 57: 10257-74. PMID 25255204 DOI: 10.1021/Jm501100B |
0.353 |
|
2014 |
Smith DT, Njardarson JT. A scalable rhodium-catalyzed intermolecular aziridination reaction. Angewandte Chemie (International Ed. in English). 53: 4278-80. PMID 24596144 DOI: 10.1002/Anie.201400502 |
0.328 |
|
2014 |
Yang Q, Draghici C, Njardarson JT, Li F, Smith BR, Das P. Evolution of an oxidative dearomatization enabled total synthesis of vinigrol. Organic & Biomolecular Chemistry. 12: 330-44. PMID 24258093 DOI: 10.1039/C3Ob42191K |
0.5 |
|
2014 |
Guo B, Vitaku E, Njardarson JT. Mild stereoselective formation of tri- and tetrasubstituted olefins by regioselective ring opening of 1,1-disubstituted vinyl oxiranes with dialkyl dithiophosphates Tetrahedron Letters. 55: 3232-3234. DOI: 10.1016/J.Tetlet.2014.04.028 |
0.478 |
|
2013 |
Yang Q, Njardarson JT. Base mediated deprotection strategies for trifluoroethyl (TFE) ethers, a new alcohol protecting group. Tetrahedron Letters. 54. PMID 24391289 DOI: 10.1016/J.Tetlet.2013.10.097 |
0.442 |
|
2013 |
Guo B, Njardarson JT. Z-Selective ring opening of vinyl oxetanes with dialkyl dithiophosphate nucleophiles. Chemical Communications (Cambridge, England). 49: 10802-4. PMID 24121797 DOI: 10.1039/C3Cc46660D |
0.445 |
|
2013 |
Ilardi EA, Njardarson JT. Ring expansions of vinyloxiranes, -thiiranes, and -aziridines: synthetic approaches, challenges, and catalytic success stories. The Journal of Organic Chemistry. 78: 9533-40. PMID 24024961 DOI: 10.1021/Jo401776S |
0.474 |
|
2013 |
Yang Q, Njardarson JT, Draghici C, Li F. Total synthesis of vinigrol. Angewandte Chemie (International Ed. in English). 52: 8648-51. PMID 23818094 DOI: 10.1002/Anie.201304624 |
0.455 |
|
2013 |
Mack DJ, Njardarson JT. Syntheses and structural confirmations of members of a heterocycle-containing family of labdane diterpenoids. Angewandte Chemie (International Ed. in English). 52: 1543-7. PMID 23255166 DOI: 10.1002/Anie.201208412 |
0.448 |
|
2013 |
Njardarson JT. Catalytic ring expansion adventures Synlett. 24: 787-803. DOI: 10.1055/S-0032-1318326 |
0.469 |
|
2013 |
MacK DJ, Njardarson JT. Recent advances in the metal-catalyzed ring expansions of three- and four-membered rings Acs Catalysis. 3: 272-286. DOI: 10.1021/Cs300771D |
0.454 |
|
2012 |
Mack DJ, Isoe J, Miesfeld RL, Njardarson JT. Distinct biological effects of golgicide a derivatives on larval and adult mosquitoes. Bioorganic & Medicinal Chemistry Letters. 22: 5177-81. PMID 22818079 DOI: 10.1016/J.Bmcl.2012.06.076 |
0.32 |
|
2012 |
Mack DJ, Guo B, Njardarson JT. Synthesis of allylic and homoallylic alcohols from unsaturated cyclic ethers using a mild and selective C-O reduction approach. Chemical Communications (Cambridge, England). 48: 7844-6. PMID 22751476 DOI: 10.1039/C2Cc33551D |
0.37 |
|
2012 |
Guo B, Schwarzwalder G, Njardarson JT. Catalytic ring expansion of vinyl oxetanes: asymmetric synthesis of dihydropyrans using chiral counterion catalysis. Angewandte Chemie (International Ed. in English). 51: 5675-8. PMID 22528273 DOI: 10.1002/Anie.201201367 |
0.491 |
|
2012 |
Li F, Calabrese D, Brichacek M, Lin I, Njardarson JT. Efficient synthesis of thiopyrans using a sulfur-enabled anionic cascade. Angewandte Chemie (International Ed. in English). 51: 1938-41. PMID 22234934 DOI: 10.1002/Anie.201108261 |
0.792 |
|
2012 |
Mack DJ, Batory LA, Njardarson JT. Intermolecular oxonium ylide mediated synthesis of medium-sized oxacycles. Organic Letters. 14: 378-81. PMID 22188418 DOI: 10.1021/Ol203129D |
0.818 |
|
2012 |
MacK DJ, Njardarson JT. New mechanistic insights into the copper catalyzed ring expansion of vinyl aziridines: Evidence in support of a copper(i) mediated pathway Chemical Science. 3: 3321-3325. DOI: 10.1039/C2Sc21007J |
0.401 |
|
2012 |
Njardarson JT. Reactions at your fingertips Nature Chemistry. 4: 590-590. DOI: 10.1038/Nchem.1416 |
0.309 |
|
2012 |
Draghici C, Njardarson JT. Chemistry by design: A web-based educational flashcard for exploring synthetic organic chemistry Journal of Chemical Education. 89: 1080-1082. DOI: 10.1021/Ed2006423 |
0.308 |
|
2011 |
Njardarson JT. Synthetic Efforts Toward [3.3.1] Bridged Bicyclic Phloroglucinol Natural Products. Tetrahedron. 67: 7631-7666. PMID 23172980 DOI: 10.1016/J.Tet.2011.06.079 |
0.378 |
|
2011 |
Lecomte N, Njardarson JT, Nagorny P, Yang G, Downey R, Ouerfelli O, Moore MA, Danishefsky SJ. Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin. Proceedings of the National Academy of Sciences of the United States of America. 108: 15074-8. PMID 21808037 DOI: 10.1073/Pnas.1015247108 |
0.665 |
|
2011 |
Brichacek M, Villalobos MN, Plichta A, Njardarson JT. Stereospecific ring expansion of chiral vinyl aziridines. Organic Letters. 13: 1110-3. PMID 21309528 DOI: 10.1021/Ol200263G |
0.801 |
|
2011 |
McGrath NA, Binner JR, Markopoulos G, Brichacek M, Njardarson JT. An efficient oxidative dearomatization-radical cyclization approach to symmetrically substituted bicyclic guttiferone natural products. Chemical Communications (Cambridge, England). 47: 209-11. PMID 20607196 DOI: 10.1039/C0Cc01419B |
0.802 |
|
2010 |
Nagorny P, Krauss I, Njardarson JT, Perez L, Gaul C, Yang G, Ouerfelli O, Danishefsky SJ. Confirmation of the Structures of Synthetic Derivatives of Migrastatin in the Light of Recently Disclosed Crystallographically Based Claims. Tetrahedron Letters. 51: 3873-3875. PMID 20676392 DOI: 10.1016/J.Tetlet.2010.05.056 |
0.759 |
|
2010 |
Brichacek M, Batory LA, Njardarson JT. Stereoselective ring expansion of vinyl oxiranes: mechanistic insights and natural product total synthesis. Angewandte Chemie (International Ed. in English). 49: 1648-51. PMID 20135664 DOI: 10.1002/Anie.200906830 |
0.796 |
|
2010 |
McGrath NA, Brichacek M, Njardarson JT. A graphical journey of innovative organic architectures that have improved our lives Journal of Chemical Education. 87: 1348-1349. DOI: 10.1021/Ed1003806 |
0.737 |
|
2010 |
Brichacek M, Batory LA, McGrath NA, Njardarson JT. The strategic marriage of method and motif. Total synthesis of varitriol Tetrahedron. 66: 4832-4840. DOI: 10.1016/J.Tet.2010.03.038 |
0.78 |
|
2009 |
McGrath NA, Bartlett ES, Sittihan S, Njardarson JT. A concise ring-expansion route to the compact core of platensimycin. Angewandte Chemie (International Ed. in English). 48: 8543-6. PMID 19798708 DOI: 10.1002/Anie.200903347 |
0.799 |
|
2009 |
Morton JG, Draghici C, Kwon LD, Njardarson JT. Rapid assembly of vinigrol's unique carbocyclic skeleton. Organic Letters. 11: 4492-5. PMID 19728692 DOI: 10.1021/Ol901519K |
0.779 |
|
2009 |
Brichacek M, Njardarson JT. Creative approaches towards the synthesis of 2,5-dihydro- furans, thiophenes, and pyrroles. One method does not fit all! Organic & Biomolecular Chemistry. 7: 1761-70. PMID 19590767 DOI: 10.1039/B900236G |
0.771 |
|
2009 |
Morton JGM, Kwon LD, Freeman JD, Njardarson JT. Thieme Chemistry Journal awardees - Where are they now? Efforts towards the total synthesis of vinigrol Synlett. 23-27. DOI: 10.1055/S-0028-1087378 |
0.508 |
|
2009 |
Morton JGM, Kwon LD, Freeman JD, Njardarson JT. An Adler-Becker oxidation approach to vinigrol Tetrahedron Letters. 50: 1684-1686. DOI: 10.1016/J.Tetlet.2009.01.134 |
0.371 |
|
2008 |
McGrath NA, Lee CA, Araki H, Brichacek M, Njardarson JT. An efficient substrate-controlled approach towards hypoestoxide, a member of a family of diterpenoid natural products with an inside-out [9.3.1]bicyclic core. Angewandte Chemie (International Ed. in English). 47: 9450-3. PMID 18979485 DOI: 10.1002/Anie.200804237 |
0.773 |
|
2008 |
Brichacek M, Lee D, Njardarson JT. Lewis acid catalyzed [1,3]-sigmatropic rearrangement of vinyl aziridines. Organic Letters. 10: 5023-6. PMID 18841992 DOI: 10.1021/Ol802123E |
0.765 |
|
2007 |
Rogers E, Araki H, Batory LA, McInnis CE, Njardarson JT. Highly selective copper-catalyzed ring expansion of vinyl thiiranes: application to synthesis of biotin and the heterocyclic core of plavix. Journal of the American Chemical Society. 129: 2768-9. PMID 17302422 DOI: 10.1021/Ja069059H |
0.82 |
|
2006 |
Batory LA, McInnis CE, Njardarson JT. Copper-catalyzed rearrangement of vinyl oxiranes. Journal of the American Chemical Society. 128: 16054-5. PMID 17165756 DOI: 10.1021/Ja067073O |
0.783 |
|
2005 |
Shan D, Chen L, Njardarson JT, Gaul C, Ma X, Danishefsky SJ, Huang XY. Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice. Proceedings of the National Academy of Sciences of the United States of America. 102: 3772-6. PMID 15728385 DOI: 10.1073/Pnas.0500658102 |
0.425 |
|
2004 |
Gaul C, Njardarson JT, Shan D, Dorn DC, Wu KD, Tong WP, Huang XY, Moore MA, Danishefsky SJ. The migrastatin family: discovery of potent cell migration inhibitors by chemical synthesis. Journal of the American Chemical Society. 126: 11326-37. PMID 15355116 DOI: 10.1021/Ja048779Q |
0.611 |
|
2004 |
Njardarson JT, Gaul C, Shan D, Huang XY, Danishefsky SJ. Discovery of potent cell migration inhibitors through total synthesis: lessons from structure-activity studies of (+)-migrastatin. Journal of the American Chemical Society. 126: 1038-40. PMID 14746469 DOI: 10.1021/Ja039714A |
0.518 |
|
2003 |
Spiegel DA, Njardarson JT, McDonald IM, Wood JL. The art of innovation in organic chemistry: synthetic efforts toward the phomoidrides. Chemical Reviews. 103: 2691-727. PMID 12848583 DOI: 10.1021/Cr020408+ |
0.704 |
|
2003 |
Gaul C, Njardarson JT, Danishefsky SJ. The total synthesis of (+)-migrastatin. Journal of the American Chemical Society. 125: 6042-3. PMID 12785819 DOI: 10.1021/Ja0349103 |
0.647 |
|
2003 |
Wood JL, Graeber JK, Njardarson JT. Application of phenolic oxidation chemistry in synthesis: Preparation of the BCE ring system of ryanodine Tetrahedron. 59: 8855-8858. DOI: 10.1016/J.Tet.2003.05.001 |
0.75 |
|
2002 |
Njardarson JT, Biswas K, Danishefsky SJ. Application of hitherto unexplored macrocyclization strategies in the epothilone series: novel epothilone analogs by total synthesis. Chemical Communications (Cambridge, England). 2759-61. PMID 12478733 DOI: 10.1039/B209941A |
0.615 |
|
2002 |
Rivkin A, Njardarson JT, Biswas K, Chou TC, Danishefsky SJ. Total syntheses of [17]- and [18]dehydrodesoxyepothilones B via a concise ring-closing metathesis-based strategy: correlation of ring size with biological activity in the epothilone series. The Journal of Organic Chemistry. 67: 7737-40. PMID 12398497 DOI: 10.1021/Jo0204294 |
0.544 |
|
2002 |
Biswas K, Lin H, Njardarson JT, Chappell MD, Chou TC, Guan Y, Tong WP, He L, Horwitz SB, Danishefsky SJ. Highly concise routes to epothilones: the total synthesis and evaluation of epothilone 490. Journal of the American Chemical Society. 124: 9825-32. PMID 12175242 DOI: 10.1021/Ja0262333 |
0.617 |
|
2002 |
Drutu I, Njardarson JT, Wood JL. Reactive dienes: intramolecular aromatic oxidation of 3-(2-hydroxyphenyl)-propionic acids. Organic Letters. 4: 493-6. PMID 11843574 DOI: 10.1021/Ol0169776 |
0.774 |
|
2002 |
Spiegel DA, Njardarson JT, Wood JL. CP-263,114 synthetic studies. Construction of an isotwistane ring system via rhodium carbenoid C-H insertion Tetrahedron. 58: 6545-6554. DOI: 10.1016/S0040-4020(02)00664-6 |
0.665 |
|
2001 |
Njardarson JT, McDonald IM, Spiegel DA, Inoue M, Wood JL. An expeditious approach toward the total synthesis of CP-263,114. Organic Letters. 3: 2435-8. PMID 11483028 DOI: 10.1021/Ol015979N |
0.793 |
|
2001 |
Njardarson JT, Wood JL. Evolution of a synthetic approach to CP-263,114. Organic Letters. 3: 2431-4. PMID 11483027 DOI: 10.1021/Ol015978V |
0.527 |
|
1994 |
Geirsson JKF, Njardarson JT. A facile synthesis of α-phosphono esters through methoxycarbonylation of α-phosphono carbanions Tetrahedron Letters. 35: 9071-9072. DOI: 10.1016/0040-4039(94)88430-7 |
0.342 |
|
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