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Matthew Mark Weiss - Publications

Affiliations: 
2001 Yale University, New Haven, CT 
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18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 DiMauro EF, Altmann S, Berry LM, Bregman H, Chakka N, Chu-Moyer M, Feric Bojic E, Foti RS, Fremeau RT, Gao H, Gunaydin H, Guzman-Perez A, Hall BE, Huang H, Jarosh M, ... ... Weiss MM, et al. Application of a Parallel Synthetic Strategy in the Discovery of Biaryl Acyl Sulfonamides as Efficient and Selective NaV1.7 Inhibitors. Journal of Medicinal Chemistry. PMID 27441383 DOI: 10.1021/acs.jmedchem.6b00425  0.56
2015 Cheng Y, Brown J, Judd TC, Lopez P, Qian W, Powers TS, Chen JJ, Bartberger MD, Chen K, Dunn RT, Epstein O, Fremeau RT, Harried S, Hickman D, Hitchcock SA, ... ... Weiss MM, et al. An Orally Available BACE1 Inhibitor That Affords Robust CNS Aβ Reduction without Cardiovascular Liabilities. Acs Medicinal Chemistry Letters. 6: 210-5. PMID 25699151 DOI: 10.1021/ml500458t  0.56
2015 Chen JJ, Liu Q, Yuan C, Gore V, Lopez P, Ma V, Amegadzie A, Qian W, Judd TC, Minatti AE, Brown J, Cheng Y, Xue M, Zhong W, Dineen TA, ... ... Weiss MM, et al. Development of 2-aminooxazoline 3-azaxanthenes as orally efficacious β-secretase inhibitors for the potential treatment of Alzheimer's disease. Bioorganic & Medicinal Chemistry Letters. 25: 767-74. PMID 25613679 DOI: 10.1016/j.bmcl.2014.12.092  0.56
2014 Epstein O, Bryan MC, Cheng AC, Derakhchan K, Dineen TA, Hickman D, Hua Z, Human JB, Kreiman C, Marx IE, Weiss MM, Wahl RC, Wen PH, Whittington DA, Wood S, et al. Lead optimization and modulation of hERG activity in a series of aminooxazoline xanthene β-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors. Journal of Medicinal Chemistry. 57: 9796-810. PMID 25389560 DOI: 10.1021/jm501266w  0.56
2014 Dineen TA, Chen K, Cheng AC, Derakhchan K, Epstein O, Esmay J, Hickman D, Kreiman CE, Marx IE, Wahl RC, Wen PH, Weiss MM, Whittington DA, Wood S, Fremeau RT, et al. Inhibitors of β-site amyloid precursor protein cleaving enzyme (BACE1): identification of (S)-7-(2-fluoropyridin-3-yl)-3-((3-methyloxetan-3-yl)ethynyl)-5'H-spiro[chromeno[2,3-b]pyridine-5,4'-oxazol]-2'-amine (AMG-8718). Journal of Medicinal Chemistry. 57: 9811-31. PMID 25363711 DOI: 10.1021/jm5012676  0.56
2013 Gunaydin H, Weiss MM, Sun Y. De novo prediction of p-glycoprotein-mediated efflux liability for druglike compounds. Acs Medicinal Chemistry Letters. 4: 108-12. PMID 24900570 DOI: 10.1021/ml300314h  0.56
2012 Kaller MR, Harried SS, Albrecht B, Amarante P, Babu-Khan S, Bartberger MD, Brown J, Brown R, Chen K, Cheng Y, Citron M, Croghan MD, Graceffa R, Hickman D, Judd T, ... ... Weiss MM, et al. A Potent and Orally Efficacious, Hydroxyethylamine-Based Inhibitor of β-Secretase. Acs Medicinal Chemistry Letters. 3: 886-91. PMID 24900403 DOI: 10.1021/ml3000148  0.56
2012 Wood S, Wen PH, Zhang J, Zhu L, Luo Y, Babu-Khan S, Chen K, Pham R, Esmay J, Dineen TA, Kaller MR, Weiss MM, Hitchcock SA, Citron M, Zhong W, et al. Establishing the relationship between in vitro potency, pharmacokinetic, and pharmacodynamic parameters in a series of orally available, hydroxyethylamine-derived β-secretase inhibitors. The Journal of Pharmacology and Experimental Therapeutics. 343: 460-7. PMID 22911925 DOI: 10.1124/jpet.112.197954  0.56
2012 Dineen TA, Weiss MM, Williamson T, Acton P, Babu-Khan S, Bartberger MD, Brown J, Chen K, Cheng Y, Citron M, Croghan MD, Dunn RT, Esmay J, Graceffa RF, Harried SS, et al. Design and synthesis of potent, orally efficacious hydroxyethylamine derived β-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors. Journal of Medicinal Chemistry. 55: 9025-44. PMID 22468684 DOI: 10.1021/jm300118s  0.56
2012 Weiss MM, Williamson T, Babu-Khan S, Bartberger MD, Brown J, Chen K, Cheng Y, Citron M, Croghan MD, Dineen TA, Esmay J, Graceffa RF, Harried SS, Hickman D, Hitchcock SA, et al. Design and preparation of a potent series of hydroxyethylamine containing β-secretase inhibitors that demonstrate robust reduction of central β-amyloid. Journal of Medicinal Chemistry. 55: 9009-24. PMID 22468639 DOI: 10.1021/jm300119p  0.56
2009 Navarro Villalobos M, Wood JL, Jeong S, Benson CL, Zeman SM, McCarty C, Weiss MM, Salcedo A, Jenkins J. Total syntheses of (+)- and (-)-syringolides 3 and of (+)- and (-)-syributins 1, 2 and 3 Tetrahedron. 65: 8091-8098. DOI: 10.1016/j.tet.2009.07.055  0.56
2008 Harmange JC, Weiss MM, Germain J, Polverino AJ, Borg G, Bready J, Chen D, Choquette D, Coxon A, DeMelfi T, DiPietro L, Doerr N, Estrada J, Flynn J, Graceffa RF, et al. Naphthamides as novel and potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: design, synthesis, and evaluation. Journal of Medicinal Chemistry. 51: 1649-67. PMID 18324761 DOI: 10.1021/jm701097z  0.56
2008 Weiss MM, Harmange JC, Polverino AJ, Bauer D, Berry L, Berry V, Borg G, Bready J, Chen D, Choquette D, Coxon A, DeMelfi T, Doerr N, Estrada J, Flynn J, et al. Evaluation of a series of naphthamides as potent, orally active vascular endothelial growth factor receptor-2 tyrosine kinase inhibitors. Journal of Medicinal Chemistry. 51: 1668-80. PMID 18324759 DOI: 10.1021/jm701098w  0.56
2008 La DS, Belzile J, Bready JV, Coxon A, DeMelfi T, Doerr N, Estrada J, Flynn JC, Flynn SR, Graceffa RF, Harriman SP, Larrow JF, Long AM, Martin MW, Morrison MJ, ... ... Weiss MM, et al. Novel 2,3-dihydro-1,4-benzoxazines as potent and orally bioavailable inhibitors of tumor-driven angiogenesis. Journal of Medicinal Chemistry. 51: 1695-705. PMID 18311900 DOI: 10.1021/jm701129j  0.56
2008 Reisman SE, Ready JM, Weiss MM, Hasuoka A, Hirata M, Tamaki K, Ovaska TV, Smith CJ, Wood JL. Evolution of a synthetic strategy: total synthesis of (+/-)-welwitindolinone A isonitrile. Journal of the American Chemical Society. 130: 2087-100. PMID 18198870 DOI: 10.1021/ja076663z  0.56
2004 Ready JM, Reisman SE, Hirata M, Weiss MM, Tamaki K, Ovaska TV, Wood JL. A mild and efficient synthesis of oxindoles: progress towards the synthesis of welwitindolinone A isonitrile. Angewandte Chemie (International Ed. in English). 43: 1270-2. PMID 14991796 DOI: 10.1002/anie.200353282  0.56
2003 Dounay AB, Hatanaka K, Kodanko JJ, Oestreich M, Overman LE, Pfeifer LA, Weiss MM. Catalytic asymmetric synthesis of quaternary carbons bearing two aryl substituents. Enantioselective synthesis of 3-alkyl-3-aryl oxindoles by catalytic asymmetric intramolecular heck reactions. Journal of the American Chemical Society. 125: 6261-71. PMID 12785859 DOI: 10.1021/ja034525d  0.56
1999 Wood JL, Holubec AA, Stoltz BM, Weiss MM, Dixon JA, Doan BD, Shamji MF, Chen JM, Heffron TP. Application of reactive enols in synthesis: A versatile, efficient, and stereoselective construction of the welwitindolinone carbon skeleton [11] Journal of the American Chemical Society. 121: 6326-6327. DOI: 10.1021/ja991022s  0.56
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