| Year |
Citation |
Score |
| 2015 |
Cheng Y, Brown J, Judd TC, Lopez P, Qian W, Powers TS, Chen JJ, Bartberger MD, Chen K, Dunn RT, Epstein O, Fremeau RT, Harried S, Hickman D, Hitchcock SA, ... ... Weiss MM, et al. An Orally Available BACE1 Inhibitor That Affords Robust CNS Aβ Reduction without Cardiovascular Liabilities. Acs Medicinal Chemistry Letters. 6: 210-5. PMID 25699151 DOI: 10.1021/ml500458t |
0.491 |
|
| 2015 |
Chen JJ, Liu Q, Yuan C, Gore V, Lopez P, Ma V, Amegadzie A, Qian W, Judd TC, Minatti AE, Brown J, Cheng Y, Xue M, Zhong W, Dineen TA, ... ... Weiss MM, et al. Development of 2-aminooxazoline 3-azaxanthenes as orally efficacious β-secretase inhibitors for the potential treatment of Alzheimer's disease. Bioorganic & Medicinal Chemistry Letters. 25: 767-74. PMID 25613679 DOI: 10.1016/J.Bmcl.2014.12.092 |
0.467 |
|
| 2014 |
Epstein O, Bryan MC, Cheng AC, Derakhchan K, Dineen TA, Hickman D, Hua Z, Human JB, Kreiman C, Marx IE, Weiss MM, Wahl RC, Wen PH, Whittington DA, Wood S, et al. Lead optimization and modulation of hERG activity in a series of aminooxazoline xanthene β-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors. Journal of Medicinal Chemistry. 57: 9796-810. PMID 25389560 DOI: 10.1021/Jm501266W |
0.499 |
|
| 2014 |
Dineen TA, Chen K, Cheng AC, Derakhchan K, Epstein O, Esmay J, Hickman D, Kreiman CE, Marx IE, Wahl RC, Wen PH, Weiss MM, Whittington DA, Wood S, Fremeau RT, et al. Inhibitors of β-site amyloid precursor protein cleaving enzyme (BACE1): identification of (S)-7-(2-fluoropyridin-3-yl)-3-((3-methyloxetan-3-yl)ethynyl)-5'H-spiro[chromeno[2,3-b]pyridine-5,4'-oxazol]-2'-amine (AMG-8718). Journal of Medicinal Chemistry. 57: 9811-31. PMID 25363711 DOI: 10.1021/Jm5012676 |
0.508 |
|
| 2009 |
Navarro Villalobos M, Wood JL, Jeong S, Benson CL, Zeman SM, McCarty C, Weiss MM, Salcedo A, Jenkins J. Total syntheses of (+)- and (-)-syringolides 3 and of (+)- and (-)-syributins 1, 2 and 3 Tetrahedron. 65: 8091-8098. DOI: 10.1016/J.Tet.2009.07.055 |
0.594 |
|
| 2008 |
Harmange JC, Weiss MM, Germain J, Polverino AJ, Borg G, Bready J, Chen D, Choquette D, Coxon A, DeMelfi T, DiPietro L, Doerr N, Estrada J, Flynn J, Graceffa RF, et al. Naphthamides as novel and potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: design, synthesis, and evaluation. Journal of Medicinal Chemistry. 51: 1649-67. PMID 18324761 DOI: 10.1021/jm701097z |
0.473 |
|
| 2008 |
Reisman SE, Ready JM, Weiss MM, Hasuoka A, Hirata M, Tamaki K, Ovaska TV, Smith CJ, Wood JL. Evolution of a synthetic strategy: total synthesis of (+/-)-welwitindolinone A isonitrile. Journal of the American Chemical Society. 130: 2087-100. PMID 18198870 DOI: 10.1021/Ja076663Z |
0.716 |
|
| 2004 |
Ready JM, Reisman SE, Hirata M, Weiss MM, Tamaki K, Ovaska TV, Wood JL. A mild and efficient synthesis of oxindoles: progress towards the synthesis of welwitindolinone A isonitrile. Angewandte Chemie (International Ed. in English). 43: 1270-2. PMID 14991796 DOI: 10.1002/Anie.200353282 |
0.716 |
|
| 2003 |
Dounay AB, Hatanaka K, Kodanko JJ, Oestreich M, Overman LE, Pfeifer LA, Weiss MM. Catalytic asymmetric synthesis of quaternary carbons bearing two aryl substituents. Enantioselective synthesis of 3-alkyl-3-aryl oxindoles by catalytic asymmetric intramolecular heck reactions. Journal of the American Chemical Society. 125: 6261-71. PMID 12785859 DOI: 10.1021/Ja034525D |
0.316 |
|
| 1999 |
Wood JL, Holubec AA, Stoltz BM, Weiss MM, Dixon JA, Doan BD, Shamji MF, Chen JM, Heffron TP. Application of reactive enols in synthesis: A versatile, efficient, and stereoselective construction of the welwitindolinone carbon skeleton [11] Journal of the American Chemical Society. 121: 6326-6327. DOI: 10.1021/Ja991022S |
0.656 |
|
| Show low-probability matches. |