Deanna L. Kroetz - Publications

Biopharmaceutical Sciences University of California, San Francisco, San Francisco, CA 
pharmacology, drug metabolism

114 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Chang JL, Lee S, Tsai AC, Musinguzi N, Muzoora C, Bwana BM, Boum Y, Haberer J, Hunt PW, Martin J, Bangsberg DR, Kroetz DL, Siedner MJ. CYP2B6 genetic polymorphisms, depression, and viral suppression in adults living with HIV initiating efavirenz-containing antiretroviral therapy regimens in Uganda: pooled analysis of two prospective studies. Aids Research and Human Retroviruses. PMID 29973058 DOI: 10.1089/Aid.2018.0062  0.4
2017 Eclov RJ, Kim MJ, Chhibber A, Smith RP, Ahituv N, Kroetz DL. ABCG2 regulatory single-nucleotide polymorphisms alter in-vivo enhancer activity and expression. Pharmacogenetics and Genomics. PMID 28930109 DOI: 10.1097/Fpc.0000000000000312  0.56
2016 Yee SW, Giacomini MM, Hsueh CH, Weitz D, Liang X, Goswami S, Kinchen JM, Coelho A, Zur AA, Mertsch K, Brian W, Kroetz DL, Giacomini KM. Metabolomic and Genome-wide Association Studies Reveal Potential Endogenous Biomarkers for OATP1B1. Clinical Pharmacology and Therapeutics. PMID 27447836 DOI: 10.1002/Cpt.434  1
2016 Hertz DL, Owzar K, Lessans S, Wing C, Jiang C, Kelly WK, Patel JN, Halabi S, Furukawa Y, Wheeler HE, Sibley A, Lassiter C, Weisman LS, Watson D, Krens SD, ... ... Kroetz D, et al. Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism That Increases Risk of Docetaxel-Induced Neuropathy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27143689 DOI: 10.1158/1078-0432.Ccr-15-2823  1
2016 Lee SA, Mefford JA, Huang Y, Witte JS, Martin JN, Haas DW, Mclaren PJ, Mushiroda T, Kubo M, Byakwaga H, Hunt PW, Kroetz DL. Host Genetic Predictors of the Kynurenine Pathway of Tryptophan Catabolism Among Treated HIV-Infected Ugandans. Aids (London, England). PMID 27088321 DOI: 10.1097/Qad.0000000000001124  1
2016 Chhibber A, French CE, Yee SW, Gamazon ER, Theusch E, Qin X, Webb A, Papp AC, Wang A, Simmons CQ, Konkashbaev A, Chaudhry AS, Mitchel K, Stryke D, Ferrin TE, ... ... Kroetz DL, et al. Transcriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell lines. The Pharmacogenomics Journal. PMID 26856248 DOI: 10.1038/Tpj.2015.93  1
2015 Yuan B, Yoshino Y, Fukushima H, Markova S, Takagi N, Toyoda H, Kroetz DL. Multidrug resistance-associated protein 4 is a determinant of arsenite resistance. Oncology Reports. PMID 26497925 DOI: 10.3892/Or.2015.4343  1
2015 Komatsu M, Wheeler HE, Chung S, Low SK, Wing C, Delaney SM, Gorsic LK, Takahashi A, Kubo M, Kroetz D, Zhang W, Nakamura Y, Dolan ME. Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26015512 DOI: 10.1158/1078-0432.Ccr-15-0133  1
2015 Haenisch S, Zhao Y, Chhibber A, Kaiboriboon K, Do LV, Vogelgesang S, Barbaro NM, Alldredge BK, Lowenstein DH, Cascorbi I, Kroetz DL. SOX11 identified by target gene evaluation of miRNAs differentially expressed in focal and non-focal brain tissue of therapy-resistant epilepsy patients. Neurobiology of Disease. 77: 127-40. PMID 25766675 DOI: 10.1016/J.Nbd.2015.02.025  1
2015 Barbarino JM, Kroetz DL, Klein TE, Altman RB. PharmGKB summary: very important pharmacogene information for human leukocyte antigen B. Pharmacogenetics and Genomics. 25: 205-21. PMID 25647431 DOI: 10.1097/Fpc.0000000000000118  1
2014 Chhibber A, Kroetz DL, Tantisira KG, McGeachie M, Cheng C, Plenge R, Stahl E, Sadee W, Ritchie MD, Pendergrass SA. Genomic architecture of pharmacological efficacy and adverse events. Pharmacogenomics. 15: 2025-48. PMID 25521360 DOI: 10.2217/Pgs.14.144  1
2014 Barbarino JM, Kroetz DL, Altman RB, Klein TE. PharmGKB summary: abacavir pathway. Pharmacogenetics and Genomics. 24: 276-82. PMID 24625462 DOI: 10.1097/Fpc.0000000000000040  1
2014 Martin MA, Hoffman JM, Freimuth RR, Klein TE, Dong BJ, Pirmohamed M, Hicks JK, Wilkinson MR, Haas DW, Kroetz DL. Clinical Pharmacogenetics Implementation Consortium Guidelines for HLA-B Genotype and Abacavir Dosing: 2014 update. Clinical Pharmacology and Therapeutics. 95: 499-500. PMID 24561393 DOI: 10.1038/Clpt.2014.38  1
2014 Chhibber A, Mefford J, Stahl EA, Pendergrass SA, Baldwin RM, Owzar K, Li M, Winer EP, Hudis CA, Zembutsu H, Kubo M, Nakamura Y, McLeod HL, Ratain MJ, Shulman LN, ... ... Kroetz DL, et al. Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance). The Pharmacogenomics Journal. 14: 336-42. PMID 24513692 DOI: 10.1038/Tpj.2014.2  1
2014 Markova SM, Schwartz JB, Kroetz DL. Response to "CYP2C9 polymorphism is not a major determinant of bosentan exposure in healthy volunteers". Clinical Pharmacology and Therapeutics. 95: 252. PMID 24346422 DOI: 10.1038/Clpt.2013.239  1
2014 Nicol MR, Fedoriw Y, Mathews M, Prince HM, Patterson KB, Geller E, Mollan K, Mathews S, Kroetz DL, Kashuba AD. Expression of six drug transporters in vaginal, cervical, and colorectal tissues: Implications for drug disposition in HIV prevention. Journal of Clinical Pharmacology. 54: 574-83. PMID 24343710 DOI: 10.1002/Jcph.248  1
2014 Markova SM, Kroetz DL. ABCC4 is regulated by microRNA-124a and microRNA-506. Biochemical Pharmacology. 87: 515-22. PMID 24184504 DOI: 10.1016/J.Bcp.2013.10.017  1
2014 Chhibber A, Micheli J, Kroetz DL. Polymorphisms of Drug Transporters and Clinical Relevance Drug Transporters: Molecular Characterization and Role in Drug Disposition: Second Edition. 389-407. DOI: 10.1002/9781118705308.ch20  1
2013 Liu Y, Lu X, Nguyen S, Olson JL, Webb HK, Kroetz DL. Epoxyeicosatrienoic acids prevent cisplatin-induced renal apoptosis through a p38 mitogen-activated protein kinase-regulated mitochondrial pathway. Molecular Pharmacology. 84: 925-34. PMID 24092818 DOI: 10.1124/Mol.113.088302  1
2013 Micheli JE, Chinn LW, Shugarts SB, Patel A, Martin JN, Bangsberg DR, Kroetz DL. Measuring the overall genetic component of nevirapine pharmacokinetics and the role of selected polymorphisms: towards addressing the missing heritability in pharmacogenetic phenotypes? Pharmacogenetics and Genomics. 23: 591-6. PMID 23982262 DOI: 10.1097/Fpc.0B013E32836533A5  1
2013 Markova SM, De Marco T, Bendjilali N, Kobashigawa EA, Mefford J, Sodhi J, Le H, Zhang C, Halladay J, Rettie AE, Khojasteh C, McGlothlin D, Wu AH, Hsueh WC, Witte JS, ... ... Kroetz DL, et al. Association of CYP2C9*2 with bosentan-induced liver injury. Clinical Pharmacology and Therapeutics. 94: 678-86. PMID 23863877 DOI: 10.1038/Clpt.2013.143  1
2013 Tamraz B, Fukushima H, Wolfe AR, Kaspera R, Totah RA, Floyd JS, Ma B, Chu C, Marciante KD, Heckbert SR, Psaty BM, Kroetz DL, Kwok PY. OATP1B1-related drug-drug and drug-gene interactions as potential risk factors for cerivastatin-induced rhabdomyolysis. Pharmacogenetics and Genomics. 23: 355-64. PMID 23652407 DOI: 10.1097/Fpc.0B013E3283620C3B  1
2013 Martin MA, Kroetz DL. Abacavir pharmacogenetics--from initial reports to standard of care. Pharmacotherapy. 33: 765-75. PMID 23649914 DOI: 10.1002/Phar.1278  1
2013 Wheeler HE, Gamazon ER, Wing C, Njiaju UO, Njoku C, Baldwin RM, Owzar K, Jiang C, Watson D, Shterev I, Kubo M, Zembutsu H, Winer EP, Hudis CA, Shulman LN, ... ... Kroetz DL, et al. Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 491-9. PMID 23204130 DOI: 10.1158/1078-0432.Ccr-12-2618  1
2013 Lewis LD, Miller AA, Owzar K, Bies RR, Markova S, Jiang C, Kroetz DL, Egorin MJ, McLeod HL, Ratain MJ. The relationship of polymorphisms in ABCC2 and SLCO1B3 with docetaxel pharmacokinetics and neutropenia: CALGB 60805 (Alliance). Pharmacogenetics and Genomics. 23: 29-33. PMID 23188068 DOI: 10.1097/Fpc.0B013E32835B16D8  1
2013 Nguyen TD, Markova S, Liu W, Gow JM, Baldwin RM, Habashian M, Relling MV, Ratain MJ, Kroetz DL. Functional characterization of ABCC2 promoter polymorphisms and allele-specific expression. The Pharmacogenomics Journal. 13: 396-402. PMID 22664480 DOI: 10.1038/Tpj.2012.20  1
2013 Motsinger-Reif AA, Jorgenson E, Relling MV, Kroetz DL, Weinshilboum R, Cox NJ, Roden DM. Genome-wide association studies in pharmacogenomics: successes and lessons. Pharmacogenetics and Genomics. 23: 383-94. PMID 20639796 DOI: 10.1097/Fpc.0B013E32833D7B45  1
2013 Yee SW, Kroetz DL, Giacomini KM. The Pharmacogenomics of Membrane Transporters Project Pharmacogenomics of Human Drug Transporters: Clinical Impacts. 73-108. DOI: 10.1002/9781118353240.ch4  1
2012 Nakamura Y, Ratain MJ, Cox NJ, McLeod HL, Kroetz DL, Flockhart DA. Re: CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: the Breast International Group 1-98 trial. Journal of the National Cancer Institute. 104: 1264; author reply 1. PMID 22851270 DOI: 10.1093/Jnci/Djs304  1
2012 Baldwin RM, Owzar K, Zembutsu H, Chhibber A, Kubo M, Jiang C, Watson D, Eclov RJ, Mefford J, McLeod HL, Friedman PN, Hudis CA, Winer EP, Jorgenson EM, Witte JS, ... ... Kroetz DL, et al. A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 5099-109. PMID 22843789 DOI: 10.1158/1078-0432.Ccr-12-1590  1
2012 Lee TM, Huang L, Johnson MK, Lizak P, Kroetz D, Aweeka F, Parikh S. In vitro metabolism of piperaquine is primarily mediated by CYP3A4. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 42: 1088-95. PMID 22671777 DOI: 10.3109/00498254.2012.693972  1
2012 Peppercorn J, Shapira I, Deshields T, Kroetz D, Friedman P, Spears P, Collyar DE, Shulman LN, Dressler L, Bertagnolli MM. Ethical aspects of participation in the Database of Genotypes and Phenotypes of the National Center for Biotechnology Information: The Cancer and Leukemia Group B Experience Cancer. 118: 5060-5068. PMID 22415847 DOI: 10.1002/Cncr.27515  1
2012 Liu Y, Webb HK, Fukushima H, Micheli J, Markova S, Olson JL, Kroetz DL. Attenuation of cisplatin-induced renal injury by inhibition of soluble epoxide hydrolase involves nuclear factor κB signaling. The Journal of Pharmacology and Experimental Therapeutics. 341: 725-34. PMID 22414856 DOI: 10.1124/Jpet.111.191247  1
2012 Martin MA, Klein TE, Dong BJ, Pirmohamed M, Haas DW, Kroetz DL. Clinical pharmacogenetics implementation consortium guidelines for HLA-B genotype and abacavir dosing. Clinical Pharmacology and Therapeutics. 91: 734-8. PMID 22378157 DOI: 10.1038/clpt.2011.355  1
2012 Matsson P, Yee SW, Markova S, Morrissey K, Jenkins G, Xuan J, Jorgenson E, Kroetz DL, Giacomini KM. Discovery of regulatory elements in human ATP-binding cassette transporters through expression quantitative trait mapping. The Pharmacogenomics Journal. 12: 214-26. PMID 21383772 DOI: 10.1038/Tpj.2011.8  1
2011 Yoshino Y, Yuan B, Kaise T, Takeichi M, Tanaka S, Hirano T, Kroetz DL, Toyoda H. Contribution of aquaporin 9 and multidrug resistance-associated protein 2 to differential sensitivity to arsenite between primary cultured chorion and amnion cells prepared from human fetal membranes. Toxicology and Applied Pharmacology. 257: 198-208. PMID 21945491 DOI: 10.1016/J.Taap.2011.09.006  1
2011 Marciante KD, Durda JP, Heckbert SR, Lumley T, Rice K, McKnight B, Totah RA, Tamraz B, Kroetz DL, Fukushima H, Kaspera R, Bis JC, Glazer NL, Li G, Austin TR, et al. Cerivastatin, genetic variants, and the risk of rhabdomyolysis. Pharmacogenetics and Genomics. 21: 280-8. PMID 21386754 DOI: 10.1097/Fpc.0B013E328343Dd7D  1
2011 Kim MJ, Skewes-Cox P, Fukushima H, Hesselson S, Yee SW, Ramsey LB, Nguyen L, Eshragh JL, Castro RA, Wen CC, Stryke D, Johns SJ, Ferrin TE, Kwok PY, Relling MV, ... ... Kroetz DL, et al. Functional characterization of liver enhancers that regulate drug-associated transporters. Clinical Pharmacology and Therapeutics. 89: 571-8. PMID 21368754 DOI: 10.1038/clpt.2010.353  1
2011 Hoppe R, Brauch H, Kroetz DL, Esteller M. Exploiting the complexity of the genome and transcriptome using pharmacogenomics towards personalized medicine. Genome Biology. 12: 301. PMID 21241526 DOI: 10.1186/Gb-2011-12-1-301  1
2011 Hodges LM, Markova SM, Chinn LW, Gow JM, Kroetz DL, Klein TE, Altman RB. Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein). Pharmacogenetics and Genomics. 21: 152-61. PMID 20216335 DOI: 10.1097/Fpc.0B013E3283385A1C  1
2011 Kelly L, Fukushima H, Karchin R, Gow JM, Chinn LW, Pieper U, Segal MR, Kroetz DL, Sali A. Letter to the editor Protein Science. 20: 4-5. DOI: 10.1002/Pro.555  1
2010 Kelly L, Fukushima H, Karchin R, Gow JM, Chinn LW, Pieper U, Segal MR, Kroetz DL, Sali A. Functional hot spots in human ATP-binding cassette transporter nucleotide binding domains. Protein Science : a Publication of the Protein Society. 19: 2110-21. PMID 20799350 DOI: 10.1002/Pro.491  1
2010 Ho RH, Leake BF, Kilkenny DM, Meyer Zu Schwabedissen HE, Glaeser H, Kroetz DL, Kim RB. Polymorphic variants in the human bile salt export pump (BSEP; ABCB11): functional characterization and interindividual variability. Pharmacogenetics and Genomics. 20: 45-57. PMID 20010382 DOI: 10.1097/Fpc.0B013E3283349Eb0  1
2010 Kroetz DL, Yee SW, Giacomini KM. The pharmacogenomics of membrane transporters project: research at the interface of genomics and transporter pharmacology. Clinical Pharmacology and Therapeutics. 87: 109-16. PMID 19940846 DOI: 10.1038/Clpt.2009.226  1
2009 Kroetz DL, Ahituv N, Burchard EG, Guo S, Sali A, Giacomini KM. Institutional Profile: The University of California Pharmacogenomics Center: at the interface of genomics, biological mechanisms and drug therapy. Pharmacogenomics. 10: 1569-76. PMID 19842929 DOI: 10.2217/Pgs.09.119  1
2009 Kelly L, Pieper U, Eswar N, Hays FA, Li M, Roe-Zurz Z, Kroetz DL, Giacomini KM, Stroud RM, Sali A. A survey of integral alpha-helical membrane proteins. Journal of Structural and Functional Genomics. 10: 269-80. PMID 19760129 DOI: 10.1007/S10969-009-9069-8  1
2009 Hesselson SE, Matsson P, Shima JE, Fukushima H, Yee SW, Kobayashi Y, Gow JM, Ha C, Ma B, Poon A, Johns SJ, Stryke D, Castro RA, Tahara H, Choi JH, ... ... Kroetz DL, et al. Genetic variation in the proximal promoter of ABC and SLC superfamilies: liver and kidney specific expression and promoter activity predict variation. Plos One. 4: e6942. PMID 19742321 DOI: 10.1371/Journal.Pone.0006942  1
2009 Innocenti F, Kroetz DL, Schuetz E, Dolan ME, Ramírez J, Relling M, Chen P, Das S, Rosner GL, Ratain MJ. Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 2604-14. PMID 19349540 DOI: 10.1200/Jco.2008.20.6300  1
2009 Mayer F, Mayer N, Chinn L, Pinsonneault RL, Kroetz D, Bainton RJ. Evolutionary conservation of vertebrate blood-brain barrier chemoprotective mechanisms in Drosophila. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 3538-50. PMID 19295159 DOI: 10.1523/Jneurosci.5564-08.2009  1
2009 Chinn LW, Kroetz DL. Genetic Polymorphisms in ABC Transporters Abc Transporters and Multidrug Resistance. 411-436. DOI: 10.1002/9780470495131.ch15  1
2008 Byakika-Tusiime J, Chinn LW, Oyugi JH, Obua C, Bangsberg DR, Kroetz DL. Steady state bioequivalence of generic and innovator formulations of stavudine, lamivudine, and nevirapine in HIV-infected Ugandan adults. Plos One. 3: e3981. PMID 19096711 DOI: 10.1371/Journal.Pone.0003981  1
2008 Fife KL, Liu Y, Schmelzer KR, Tsai HJ, Kim IH, Morisseau C, Hammock BD, Kroetz DL. Inhibition of soluble epoxide hydrolase does not protect against endotoxin-mediated hepatic inflammation. The Journal of Pharmacology and Experimental Therapeutics. 327: 707-15. PMID 18815352 DOI: 10.1124/Jpet.108.142398  1
2008 Tutka P, Dempsey DA, Jacob P, Benowitz NL, Kroetz DL. Nicotine metabolism in pregnant and nonpregnant rabbits. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 10: 1385-90. PMID 18686186 DOI: 10.1080/14622200802238878  1
2008 Abla N, Chinn LW, Nakamura T, Liu L, Huang CC, Johns SJ, Kawamoto M, Stryke D, Taylor TR, Ferrin TE, Giacomini KM, Kroetz DL. The human multidrug resistance protein 4 (MRP4, ABCC4): functional analysis of a highly polymorphic gene. The Journal of Pharmacology and Experimental Therapeutics. 325: 859-68. PMID 18364470 DOI: 10.1124/Jpet.108.136523  1
2008 Gow JM, Hodges LM, Chinn LW, Kroetz DL. Substrate-dependent effects of human ABCB1 coding polymorphisms. The Journal of Pharmacology and Experimental Therapeutics. 325: 435-42. PMID 18287207 DOI: 10.1124/Jpet.107.135194  1
2008 Gow JM, Chinn LW, Kroetz DL. The effects of ABCB1 3'-untranslated region variants on mRNA stability. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 10-5. PMID 17940136 DOI: 10.1124/Dmd.107.017087  1
2007 Bangsberg DR, Kroetz DL, Deeks SG. Adherence-resistance relationships to combination HIV antiretroviral therapy. Current Hiv/Aids Reports. 4: 65-72. PMID 17547827 DOI: 10.1007/S11904-007-0010-0  1
2007 Chinn LW, Gow JM, Tse MM, Becker SL, Kroetz DL. Interindividual variability in the effect of atazanavir and saquinavir on the expression of lymphocyte P-glycoprotein. The Journal of Antimicrobial Chemotherapy. 60: 61-7. PMID 17510066 DOI: 10.1093/Jac/Dkm135  1
2007 Soranzo N, Kelly L, Martinian L, Burley MW, Thom M, Sali A, Kroetz DL, Goldstein DB, Sisodiya SM. Lack of support for a role for RLIP76 (RALBP1) in response to treatment or predisposition to epilepsy. Epilepsia. 48: 674-83. PMID 17437410 DOI: 10.1111/J.1528-1167.2007.00926.X  1
2007 Ng VY, Huang Y, Reddy LM, Falck JR, Lin ET, Kroetz DL. Cytochrome P450 eicosanoids are activators of peroxisome proliferator-activated receptor alpha. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 1126-34. PMID 17431031 DOI: 10.1124/Dmd.106.013839  1
2007 Parikh S, Ouedraogo JB, Goldstein JA, Rosenthal PJ, Kroetz DL. Amodiaquine metabolism is impaired by common polymorphisms in CYP2C8: implications for malaria treatment in Africa. Clinical Pharmacology and Therapeutics. 82: 197-203. PMID 17361129 DOI: 10.1038/sj.clpt.6100122  1
2007 Jeong H, Herskowitz I, Kroetz DL, Rine J. Function-altering SNPs in the human multidrug transporter gene ABCB1 identified using a Saccharomyces-based assay. Plos Genetics. 3: e39. PMID 17352537 DOI: 10.1371/Journal.Pgen.0030039  1
2007 Giacomini KM, Brett CM, Altman RB, Benowitz NL, Dolan ME, Flockhart DA, Johnson JA, Hayes DF, Klein T, Krauss RM, Kroetz DL, McLeod HL, Nguyen AT, Ratain MJ, Relling MV, et al. The pharmacogenetics research network: from SNP discovery to clinical drug response. Clinical Pharmacology and Therapeutics. 81: 328-45. PMID 17339863 DOI: 10.1038/Sj.Clpt.6100087  1
2007 Chinn LW, Kroetz DL. ABCB1 pharmacogenetics: progress, pitfalls, and promise. Clinical Pharmacology and Therapeutics. 81: 265-9. PMID 17259950 DOI: 10.1038/Sj.Clpt.6100052  1
2007 de Jong FA, Scott-Horton TJ, Kroetz DL, McLeod HL, Friberg LE, Mathijssen RH, Verweij J, Marsh S, Sparreboom A. Irinotecan-induced diarrhea: functional significance of the polymorphic ABCC2 transporter protein. Clinical Pharmacology and Therapeutics. 81: 42-9. PMID 17185998 DOI: 10.1038/Sj.Clpt.6100019  1
2007 Sisodiya S, Thom M, Kroetz D, Kelly L. Response to Janigro et al. [4] Epilepsia. 48: 1219-1220. DOI: 10.1111/j.1528-1167.2007.01155_5.x  1
2006 Ng VY, Morisseau C, Falck JR, Hammock BD, Kroetz DL. Inhibition of smooth muscle proliferation by urea-based alkanoic acids via peroxisome proliferator-activated receptor alpha-dependent repression of cyclin D1. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 2462-8. PMID 16917105 DOI: 10.1161/01.Atv.0000242013.29441.81  1
2006 Kroetz DL. Role for drug transporters beyond tumor resistance: hepatic functional imaging and genotyping of multidrug resistance transporters for the prediction of irinotecan toxicity. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 4225-7. PMID 16895999 DOI: 10.1200/Jco.2006.07.2355  1
2006 Xu F, Ng VY, Kroetz DL, de Montellano PR. CYP4 isoform specificity in the omega-hydroxylation of phytanic acid, a potential route to elimination of the causative agent of Refsum's disease. The Journal of Pharmacology and Experimental Therapeutics. 318: 835-9. PMID 16707724 DOI: 10.1124/Jpet.106.104976  1
2006 Komoto C, Nakamura T, Sakaeda T, Kroetz DL, Yamada T, Omatsu H, Koyama T, Okamura N, Miki I, Tamura T, Aoyama N, Kasuga M, Okumura K. MDR1 haplotype frequencies in Japanese and Caucasian, and in Japanese patients with colorectal cancer and esophageal cancer. Drug Metabolism and Pharmacokinetics. 21: 126-32. PMID 16702732 DOI: 10.2133/Dmpk.21.126  1
2006 Badagnani I, Sorani M, Edwards RH, Brown C, Castro RA, Huang CC, Stryke D, Kawamoto M, Johns SJ, Carlson EJ, Taylor T, Chan W, De La Cruz M, Ferrin TE, Burchard EG, ... ... Kroetz DL, et al. PharmGKB submission update: VI. PMT submissions of genetic variations in neurotransmitter transporters (SLC6, SLC17, and SLC18) to the PharmGKB network. Pharmacological Reviews. 58: 5-6. PMID 16507879 DOI: 10.1124/Pr.58.1.3  1
2006 Shu Y, Urban TJ, Leabman MK, Fujita T, Erdman AR, Lagpacan LL, Brown C, Castro RA, Huang CC, Stryke D, Kawamoto M, Johns SJ, Taylor TR, Chan W, De La Cruz M, ... ... Kroetz DL, et al. PharmGKB submission update: V. PMT submissions of genetic variation in SLC22 family transporters. Pharmacological Reviews. 58: 3-4. PMID 16507878 DOI: 10.1124/Pr.58.1.2  1
2006 Nguyen TD, Gow JM, Chinn LW, Kelly L, Jeong H, Huang CC, Stryke D, Kawamoto M, Johns SJ, Carlson E, Taylor T, Ferrin TE, Sali A, Giacomini KM, Kroetz DL. PharmGKB submission update: IV. PMT submissions of genetic variations in ATP-Binding cassette transporters to the PharmGKB network. Pharmacological Reviews. 58: 1-2. PMID 16507877 DOI: 10.1124/Pr.58.1.1  1
2006 Yu Z, Ng VY, Su P, Engler MM, Engler MB, Huang Y, Lin E, Kroetz DL. Induction of renal cytochrome P450 arachidonic acid epoxygenase activity by dietary gamma-linolenic acid. The Journal of Pharmacology and Experimental Therapeutics. 317: 732-8. PMID 16421287 DOI: 10.1124/Jpet.105.098558  1
2005 Andersson T, Flockhart DA, Goldstein DB, Huang SM, Kroetz DL, Milos PM, Ratain MJ, Thummel K. Drug-metabolizing enzymes: evidence for clinical utility of pharmacogenomic tests. Clinical Pharmacology and Therapeutics. 78: 559-81. PMID 16338273 DOI: 10.1016/J.Clpt.2005.08.013  1
2005 Wang D, Johnson AD, Papp AC, Kroetz DL, Sadée W. Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability. Pharmacogenetics and Genomics. 15: 693-704. PMID 16141795 DOI: 10.1097/01.Fpc.0000178311.02878.83  1
2005 Kroetz DL, Xu F. Regulation and inhibition of arachidonic acid omega-hydroxylases and 20-HETE formation. Annual Review of Pharmacology and Toxicology. 45: 413-38. PMID 15822183 DOI: 10.1146/Annurev.Pharmtox.45.120403.100045  1
2005 Seubert JM, Xu F, Graves JP, Collins JB, Sieber SO, Paules RS, Kroetz DL, Zeldin DC. Differential renal gene expression in prehypertensive and hypertensive spontaneously hypertensive rats. American Journal of Physiology. Renal Physiology. 289: F552-61. PMID 15798089 DOI: 10.1152/Ajprenal.00354.2004  1
2004 Pauli-Magnus C, Kroetz DL. Functional implications of genetic polymorphisms in the multidrug resistance gene MDR1 (ABCB1). Pharmaceutical Research. 21: 904-13. PMID 15212152 DOI: 10.1023/B:Pham.0000029276.21063.0B  1
2004 Yu Z, Davis BB, Morisseau C, Hammock BD, Olson JL, Kroetz DL, Weiss RH. Vascular localization of soluble epoxide hydrolase in the human kidney. American Journal of Physiology. Renal Physiology. 286: F720-6. PMID 14665429 DOI: 10.1152/Ajprenal.00165.2003  1
2004 Xu F, Falck JR, Ortiz de Montellano PR, Kroetz DL. Catalytic activity and isoform-specific inhibition of rat cytochrome p450 4F enzymes. The Journal of Pharmacology and Experimental Therapeutics. 308: 887-95. PMID 14634044 DOI: 10.1124/Jpet.103.059626  1
2003 Pauli-Magnus C, Feiner J, Brett C, Lin E, Kroetz DL. No effect of MDR1 C3435T variant on loperamide disposition and central nervous system effects. Clinical Pharmacology and Therapeutics. 74: 487-98. PMID 14586389 DOI: 10.1016/S0009-9236(03)00234-0  1
2003 Kroetz DL, Pauli-Magnus C, Hodges LM, Huang CC, Kawamoto M, Johns SJ, Stryke D, Ferrin TE, DeYoung J, Taylor T, Carlson EJ, Herskowitz I, Giacomini KM, Clark AG. Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene. Pharmacogenetics. 13: 481-94. PMID 12893986 DOI: 10.1097/00008571-200308000-00006  1
2003 Shu Y, Leabman MK, Feng B, Mangravite LM, Huang CC, Stryke D, Kawamoto M, Johns SJ, DeYoung J, Carlson E, Ferrin TE, Herskowitz I, Giacomini KM. Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1. Proceedings of the National Academy of Sciences of the United States of America. 100: 5902-7. PMID 12719534 DOI: 10.1073/Pnas.0730858100  1
2003 Leabman MK, Huang CC, DeYoung J, Carlson EJ, Taylor TR, de la Cruz M, Johns SJ, Stryke D, Kawamoto M, Urban TJ, Kroetz DL, Ferrin TE, Clark AG, Risch N, Herskowitz I, et al. Natural variation in human membrane transporter genes reveals evolutionary and functional constraints. Proceedings of the National Academy of Sciences of the United States of America. 100: 5896-901. PMID 12719533 DOI: 10.1073/Pnas.0730857100  1
2003 Kroetz DL, Cheang K, Finkelman R, Galinkin J, Gurley B, Johnson M, Nagy C, Reyes J, Riel M, Wagner D, Williams LS, Yasuda R, ZumBrunnen T, Sandritter T, Barker T, et al. Notes of the American Society for clinical pharmacology and therapeutics: A message from the ASCPT Membership Committee chairperson Clinical Pharmacology and Therapeutics. 73: 135.  1
2002 Xu F, Straub WO, Pak W, Su P, Maier KG, Yu M, Roman RJ, Ortiz De Montellano PR, Kroetz DL. Antihypertensive effect of mechanism-based inhibition of renal arachidonic acid omega-hydroxylase activity. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 283: R710-20. PMID 12185006 DOI: 10.1152/Ajpregu.00522.2001  1
2002 Pauli-Magnus C, Kroetz DL. MDR1 reference sequence and reference function. Clinical Pharmacology and Therapeutics. 72: 100-1. PMID 12152008 DOI: 10.1067/Mcp.2002.125561  1
2002 Kroetz DL, Zeldin DC. Cytochrome P450 pathways of arachidonic acid metabolism. Current Opinion in Lipidology. 13: 273-83. PMID 12045397 DOI: 10.1097/00041433-200206000-00007  1
2002 LeBrun LA, Xu F, Kroetz DL, Ortiz de Montellano PR. Covalent attachment of the heme prosthetic group in the CYP4F cytochrome P450 family. Biochemistry. 41: 5931-7. PMID 11980497 DOI: 10.1021/Bi025527Y  1
2002 Ring HZ, Kroetz DL. Candidate gene approach for pharmacogenetic studies. Pharmacogenomics. 3: 47-56. PMID 11966402 DOI: 10.1517/14622416.3.1.47  1
2001 Pauli-Magnus C, DeYoung J, Herskowitz I, Giacomini KM, Kroetz DL. Ethnic differences in the allele frequency of polymorphisms in the MDR1 gene Clinical Pharmacology and Therapeutics. 69: P75.  1
2001 Lacayo CI, Pak W, Benowitz NL, Tracy TS, Kroetz DL. Transport and disposition of nicotine in the human placenta Clinical Pharmacology and Therapeutics. 69: P95.  1
2001 Pauli-Magnus C, Lacayo CI, Kroetz DL. Antimalarial drugs are not substrates of human P-glycoprotein Clinical Pharmacology and Therapeutics. 69: P76.  1
2000 Yu Z, Xu F, Huse LM, Morisseau C, Draper AJ, Newman JW, Parker C, Graham L, Engler MM, Hammock BD, Zeldin DC, Kroetz DL. Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids. Circulation Research. 87: 992-8. PMID 11090543 DOI: 10.1161/01.Res.87.11.992  1
2000 Yu Z, Huse LM, Adler P, Graham L, Ma J, Zeldin DC, Kroetz DL. Increased CYP2J expression and epoxyeicosatrienoic acid formation in spontaneously hypertensive rat kidney. Molecular Pharmacology. 57: 1011-20. PMID 10779386  1
2000 Spiegelstein O, Kroetz DL, Levy RH, Yagen B, Hurst SI, Levi M, Haj-Yehia A, Bialer M. Structure activity relationship of human microsomal epoxide hydrolase inhibition by amide and acid analogues of valproic acid. Pharmaceutical Research. 17: 216-21. PMID 10751038 DOI: 10.1023/A:1007577600088  1
2000 Zhang L, Gorset W, Washington CB, Blaschke TF, Kroetz DL, Giacomini KM. Interactions of HIV protease inhibitors with a human organic cation transporter in a mammalian expression system. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 28: 329-34. PMID 10681378  1
2000 Hoch U, Zhang Z, Kroetz DL, Ortiz de Montellano PR. Structural determination of the substrate specificities and regioselectivities of the rat and human fatty acid omega-hydroxylases. Archives of Biochemistry and Biophysics. 373: 63-71. PMID 10620324 DOI: 10.1006/Abbi.1999.1504  1
1999 Engler MM, Engler MB, Kroetz DL, Boswell KD, Neeley E, Krassner SM. The effects of a diet rich in docosahexaenoic acid on organ and vascular fatty acid composition in spontaneously hypertensive rats. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 61: 289-95. PMID 10670690 DOI: 10.1054/Plef.1999.0102  1
1999 Engler MM, Engler MB, Goodfriend TL, Ball DL, Yu Z, Su P, Kroetz DL. Docosahexaenoic acid is an antihypertensive nutrient that affects aldosterone production in SHR. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 221: 32-8. PMID 10320629 DOI: 10.1046/J.1525-1373.1999.D01-51.X  1
1999 Kroetz DL, Waddell DS, Schweizer A, Bianchi P, Ladouce N, Pineau T. PPARα-dependent induction of renal CYP4A expression by fasting Clinical Pharmacology and Therapeutics. 65: 188. DOI: 10.1016/S0009-9236(99)80283-5  1
1998 Kroetz DL, Yook P, Costet P, Bianchi P, Pineau T. Peroxisome proliferator-activated receptor alpha controls the hepatic CYP4A induction adaptive response to starvation and diabetes. The Journal of Biological Chemistry. 273: 31581-9. PMID 9813074 DOI: 10.1074/Jbc.273.47.31581  1
1998 Wang H, Dick R, Yin H, Licad-Coles E, Kroetz DL, Szklarz G, Harlow G, Halpert JR, Correia MA. Structure-function relationships of human liver cytochromes P450 3A: aflatoxin B1 metabolism as a probe. Biochemistry. 37: 12536-45. PMID 9730826 DOI: 10.1021/Bi980895G  1
1998 Su P, Kaushal KM, Kroetz DL. Inhibition of renal arachidonic acid omega-hydroxylase activity with ABT reduces blood pressure in the SHR. The American Journal of Physiology. 275: R426-38. PMID 9688677 DOI: 10.1152/Ajpregu.1998.275.2.R426  1
1998 Ping SU, Maya Kaushal K, Kroetz DL. Inhibition of renal arachidonic acid co-hydroxylase activity with ABT reduces blood pressure in the SHR American Journal of Physiology. 275: R426-R438.  1
1997 Kroetz DL, Huse LM, Thuresson A, Grillo MP. Developmentally regulated expression of the CYP4A genes in the spontaneously hypertensive rat kidney. Molecular Pharmacology. 52: 362-72. PMID 9281597 DOI: 10.1124/Mol.52.3.362  1
1995 Lee SS, Pineau T, Drago J, Lee EJ, Owens JW, Kroetz DL, Fernandez-Salguero PM, Westphal H, Gonzalez FJ. Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Molecular and Cellular Biology. 15: 3012-22. PMID 7539101 DOI: 10.1128/Mcb.15.6.3012  1
1994 Kerr BM, Thummel KE, Wurden CJ, Klein SM, Kroetz DL, Gonzalez FJ, Levy RH. Human liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formation. Biochemical Pharmacology. 47: 1969-79. PMID 8010982 DOI: 10.1016/0006-2952(94)90071-X  1
1993 Kroetz DL, Kerr BM, McFarland LV, Loiseau P, Wilensky AJ, Levy RH. Measurement of in vivo microsomal epoxide hydrolase activity in white subjects. Clinical Pharmacology and Therapeutics. 53: 306-15. PMID 8453849 DOI: 10.1038/Clpt.1993.26  1
1993 Kroetz DL, Loiseau P, Guyot M, Levy RH. In vivo and in vitro correlation of microsomal epoxide hydrolase inhibition by progabide. Clinical Pharmacology and Therapeutics. 54: 485-97. PMID 8222491 DOI: 10.1038/Clpt.1993.180  1
1993 Kroetz DL, McBride OW, Gonzalez FJ. Glycosylation-dependent activity of baculovirus-expressed human liver carboxylesterases: cDNA cloning and characterization of two highly similar enzyme forms. Biochemistry. 32: 11606-17. PMID 8218228 DOI: 10.1021/bi00094a018  1
1993 Pisani F, Haj-Yehia A, Fazio A, Artesi C, Oteri G, Perucca E, Kroetz DL, Levy RH, Bialer M. Carbamazepine-valnoctamide interaction in epileptic patients: in vitro/in vivo correlation. Epilepsia. 34: 954-9. PMID 8104783 DOI: 10.1111/J.1528-1157.1993.Tb02117.X  1
1993 Pisani F, Haj-Yehia A, Fazio A, Artesi C, Oteri G, Perucca E, Kroetz DL, Levy RH, Bialer M. Interaction of Carbamazepine with Valnoctamide: Data 'in vitro' and in patients with epilepsy | INTERAZIONE DELLA CARBAMAZEPINA CON LA VALNOCTAMIDE: DATI 'IN VITRO' ED IN PAZIENTI CON EPILESSIA Bollettino - Lega Italiana Contro L'Epilessia. 159.  1
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