Year |
Citation |
Score |
2022 |
Wong DR, Conrad J, Johnson N, Ayers J, Laeremans A, Lee JC, Lee J, Prusiner SB, Bandyopadhyay S, Butte AJ, Paras NA, Keiser MJ. Trans-channel fluorescence learning improves high-content screening for Alzheimer's disease therapeutics. Nature Machine Intelligence. 4: 583-595. PMID 36276634 DOI: 10.1038/s42256-022-00490-8 |
0.67 |
|
2021 |
Nguyen TH, O'Brien CJ, Tran MLN, Olson SH, Settineri NS, Prusiner SB, Paras NA, Conrad J. Water-Soluble Iridium Photoredox Catalyst for the Trifluoromethylation of Biomolecule Substrates in Phosphate Buffered Saline Solvent. Organic Letters. PMID 33929208 DOI: 10.1021/acs.orglett.1c00871 |
0.708 |
|
2021 |
Lozano C, Ramirez C, Sin N, Viart HM, Prusiner SB, Paras NA, Conrad J. Silver Benzoate Facilitates the Copper-Catalyzed C-N Coupling of Iodoazoles with Aromatic Nitrogen Heterocycles. Acs Omega. 6: 9804-9812. PMID 33869960 DOI: 10.1021/acsomega.1c00458 |
0.727 |
|
2020 |
Li Y, Vaz RJ, Olson SH, Munson M, Paras NA, Conrad J. Selectivity in the Addition of Electron Deficient Radicals to the 2 Position of Indoles. European Journal of Organic Chemistry. 2020: 5828-5832. PMID 33692651 DOI: 10.1002/Ejoc.201901784 |
0.686 |
|
2020 |
Grandjean JM, Jiu AY, West JW, Aoyagi A, Droege DG, Elepano M, Hirasawa M, Hirouchi M, Murakami R, Lee J, Sasaki K, Hirano S, Ohyama T, Tang BC, Vaz RJ, ... ... Conrad J, et al. Discovery of 4-Piperazine Isoquinoline Derivatives as Potent and Brain-Permeable Tau Prion Inhibitors with CDK8 Activity. Acs Medicinal Chemistry Letters. 11: 127-132. PMID 32071678 DOI: 10.1021/Acsmedchemlett.9B00480 |
0.665 |
|
2018 |
O'Brien CJ, Droege DG, Jiu AY, Gandhi SS, Paras NA, Olson SH, Conrad J. Photoredox Cyanomethylation of Indoles: Catalyst Modification and Mechanism. The Journal of Organic Chemistry. PMID 29940725 DOI: 10.1021/Acs.Joc.8B01146 |
0.766 |
|
2015 |
Welin ER, Warkentin AA, Conrad JC, MacMillan DW. Enantioselective α-Alkylation of Aldehydes by Photoredox Organocatalysis: Rapid Access to Pharmacophore Fragments from β-Cyanoaldehydes. Angewandte Chemie (International Ed. in English). 54: 9668-72. PMID 26130043 DOI: 10.1002/Anie.201503789 |
0.681 |
|
2015 |
Imrich HG, Conrad J, Bubrin D, Beifuss U. From nitrobenzenes to substituted tetrahydroquinolines in a single step by a domino reduction/imine formation/aza-diels-alder reaction. The Journal of Organic Chemistry. 80: 2319-32. PMID 25622151 DOI: 10.1021/jo502882y |
0.35 |
|
2014 |
Peifer M, Berger R, Shurtleff VW, Conrad JC, MacMillan DW. A general and enantioselective approach to pentoses: a rapid synthesis of PSI-6130, the nucleoside core of sofosbuvir. Journal of the American Chemical Society. 136: 5900-3. PMID 24670208 DOI: 10.1021/Ja502205Q |
0.679 |
|
2014 |
Omar MA, Conrad J, Beifuss U. Copper-catalyzed domino reaction between 1-(2-halophenyl)methanamines and amidines or imidates for the synthesis of 2-substituted quinazolines Tetrahedron. 70: 3061-3072. DOI: 10.1016/j.tet.2014.02.066 |
0.348 |
|
2014 |
Sudheendran K, Schmidt D, Frey W, Conrad J, Beifuss U. Facile synthesis of 3,5-diaryl-1,2,4-triazoles via copper-catalyzed domino nucleophilic substitution/oxidative cyclization using amidines or imidates as substrates Tetrahedron. 70: 1635-1645. DOI: 10.1016/j.tet.2014.01.019 |
0.302 |
|
2013 |
Abdel-Mohsen HT, Conrad J, Beifuss U. Laccase-catalyzed domino reaction between catechols and 6-substituted 1,2,3,4-tetrahydro-4-oxo-2-thioxo-5-pyrimidinecarbonitriles for the synthesis of pyrimidobenzothiazole derivatives. The Journal of Organic Chemistry. 78: 7986-8003. PMID 23888998 DOI: 10.1021/jo401193e |
0.369 |
|
2013 |
Aljaar N, Conrad J, Beifuss U. Synthesis of 2-aryl-1,2-dihydrophthalazines via reaction of 2-(bromomethyl)benzaldehydes with arylhydrazines. The Journal of Organic Chemistry. 78: 1045-53. PMID 23256775 DOI: 10.1021/jo302491x |
0.359 |
|
2013 |
Aljaar N, Malakar CC, Conrad J, Frey W, Beifuss U. Reaction of 1-nitroso-2-naphthols with α-functionalized ketones and related compounds: the unexpected formation of decarbonylated 2-substituted naphtho[1,2-d][1,3]oxazoles. The Journal of Organic Chemistry. 78: 154-66. PMID 23181942 DOI: 10.1021/jo3022956 |
0.353 |
|
2012 |
Aljaar N, Malakar CC, Conrad J, Strobel S, Schleid T, Beifuss U. Cu-catalyzed reaction of 1,2-dihalobenzenes with 1,3-cyclohexanediones for the synthesis of 3,4-dihydrodibenzo[b,d]furan-1(2H)-ones. The Journal of Organic Chemistry. 77: 7793-803. PMID 22917488 DOI: 10.1021/jo3014275 |
0.315 |
|
2012 |
Constantin MA, Conrad J, Meri?or E, Koschorreck K, Urlacher VB, Beifuss U. Oxidative dimerization of (E)- and (Z)-2-propenylsesamol with O2 in the presence and absence of laccases and other catalysts: selective formation of carpanones and benzopyrans under different reaction conditions. The Journal of Organic Chemistry. 77: 4528-43. PMID 22458664 DOI: 10.1021/jo300263k |
0.324 |
|
2012 |
Hajdok S, Conrad J, Beifuss U. Laccase-catalyzed domino reactions between hydroquinones and cyclic 1,3-dicarbonyls for the regioselective synthesis of substituted p-benzoquinones. The Journal of Organic Chemistry. 77: 445-59. PMID 22117114 DOI: 10.1021/jo202082v |
0.308 |
|
2011 |
Shah DD, Conrad JA, Heinz B, Brownlee JM, Moran GR. Evidence for the mechanism of hydroxylation by 4-hydroxyphenylpyruvate dioxygenase and hydroxymandelate synthase from intermediate partitioning in active site variants. Biochemistry. 50: 7694-704. PMID 21815644 DOI: 10.1021/Bi2009344 |
0.311 |
|
2011 |
Kwiatkowski P, Beeson TD, Conrad JC, MacMillan DW. Enantioselective organocatalytic α-fluorination of cyclic ketones. Journal of the American Chemical Society. 133: 1738-41. PMID 21247133 DOI: 10.1021/Ja111163U |
0.724 |
|
2010 |
Devery JJ, Conrad JC, MacMillan DW, Flowers RA. Mechanistic complexity in organo-SOMO activation. Angewandte Chemie (International Ed. in English). 49: 6106-10. PMID 20632343 DOI: 10.1002/Anie.201001673 |
0.648 |
|
2010 |
Conrad JC, Kong J, Laforteza BN, MacMillan DWC. ChemInform Abstract: Enantioselective α-Arylation of Aldehydes via Organo-SOMO Catalysis. An ortho-Selective Arylation Reaction Based on an Open-Shell Pathway. Cheminform. 41. DOI: 10.1002/chin.201004028 |
0.762 |
|
2009 |
Conrad JC, Kong J, Laforteza BN, MacMillan DW. Enantioselective alpha-arylation of aldehydes via organo-SOMO catalysis. An ortho-selective arylation reaction based on an open-shell pathway. Journal of the American Chemical Society. 131: 11640-1. PMID 19639997 DOI: 10.1021/Ja9026902 |
0.754 |
|
2007 |
Conrad JC, Eelman MD, Silva JA, Monfette S, Parnas HH, Snelgrove JL, Fogg DE. Oligomers as intermediates in ring-closing metathesis. Journal of the American Chemical Society. 129: 1024-5. PMID 17263371 DOI: 10.1021/Ja067531T |
0.35 |
|
2006 |
Conrad JC, Snelgrove JL, Eeelman MD, Hall S, Fogg DE. Ruthenium aryloxide catalysts: Synthesis and applications in ring-closing metathesis Journal of Molecular Catalysis a: Chemical. 254: 105-110. DOI: 10.1016/J.Molcata.2006.03.031 |
0.34 |
|
2005 |
Conrad JC, Parnas HH, Snelgrove JL, Fogg DE. Highly efficient Ru-pseudohalide catalysts for olefin metathesis. Journal of the American Chemical Society. 127: 11882-3. PMID 16117494 DOI: 10.1021/Ja042736S |
0.354 |
|
2003 |
Conrad JC, Amoroso D, Czechura P, Yap GPA, Fogg DE. The First Highly Active, Halide-Free Ruthenium Catalyst for Olefin Metathesis Organometallics. 22: 3634-3636. DOI: 10.1021/Om030494J |
0.314 |
|
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