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Thomas W. Bell, Ph.D. - Publications

Affiliations: 
1982-1995 Chemistry Stony Brook University, Stony Brook, NY, United States 
 1996- University of Nevada, Reno, Reno, NV, United States 
Area:
Medicinal chemistry, HIV
Website:
http://www.unr.edu/chemistry/people/thomas-bell
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50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Berger K, Pauwels E, Parkinson G, Landberg G, Le T, Demillo VG, Lumangtad LA, Jones DE, Islam MA, Olsen R, Kapri T, Intasiri A, Vermeire K, Rhost S, Bell TW. Reduction of Progranulin-Induced Breast Cancer Stem Cell Propagation by Sortilin-Targeting Cyclotriazadisulfonamide (CADA) Compounds. Journal of Medicinal Chemistry. PMID 34428050 DOI: 10.1021/acs.jmedchem.1c00943  0.759
2020 Zavaleta A, Lykhin AO, Monteiro JHSK, Uchida S, Bell TW, de Bettencourt-Dias A, Varganov SA, Gallucci J. Full Visible Spectrum and White Light Emission with a Single, Input-Tunable Organic Fluorophore. Journal of the American Chemical Society. PMID 33202131 DOI: 10.1021/jacs.0c08182  0.606
2020 Lumangtad LA, Claeys E, Hamal S, Intasiri A, Basrai C, Yen-Pon E, Beenfeldt D, Vermeire K, Bell TW. Syntheses and anti-HIV and human cluster of differentiation 4 (CD4) down-modulating potencies of pyridine-fused cyclotriazadisulfonamide (CADA) compounds. Bioorganic & Medicinal Chemistry. 28: 115816. PMID 33181479 DOI: 10.1016/j.bmc.2020.115816  0.814
2019 Ali R, Anugu S, Chawla R, Demillo VG, Goulinet-Mateo F, Gyawali S, Hamal S, Jones DE, Lamprecht K, Le T, Lumangtad LA, Pflug NC, Sama A, Scarbrough ED, Bell TW. Tsuji-Trost Cyclization of Disulfonamides: Synthesis of 12-Membered, 11-Membered, and Pyridine-Fused Macrocyclic Triamines. Acs Omega. 4: 1254-1264. PMID 30729225 DOI: 10.1021/acsomega.8b02555  0.723
2016 Van Puyenbroeck V, Claeys E, Schols D, Bell TW, Vermeire K. A proteomic survey indicates sortilin as a secondary substrate of the ER translocation inhibitor cyclotriazadisulfonamide (CADA). Molecular & Cellular Proteomics : McP. PMID 27998951 DOI: 10.1074/Mcp.M116.061051  0.336
2016 Jayasundara U, Kim H, Sahteli K, Cline JI, Bell TW. Proton-Gated Photoisomerization of Amino-Substituted Dibenzofulvene Rotors. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. PMID 27862796 DOI: 10.1002/Cphc.201601214  0.726
2016 Everhart SC, Jayasundara UK, Kim H, Procúpez-Schtirbu R, Stanbery WA, Mishler CH, Frost BJ, Cline JI, Bell TW. Synthesis and Photoisomerization of Substituted Dibenzofulvene Molecular Rotors. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27363530 DOI: 10.1002/Chem.201600854  0.668
2016 Chawla R, Van Puyenbroeck V, Pflug NC, Sama A, Ali R, Schols D, Vermeire K, Bell TW. Tuning Side Arm Electronics in Unsymmetrical Cyclotriazadisulfonamide (CADA) Endoplasmic Reticulum (ER) Translocation Inhibitors to Improve their Human Cluster of Differentiation 4 (CD4) Receptor Down-Modulating Potencies. Journal of Medicinal Chemistry. PMID 26974263 DOI: 10.1021/Acs.Jmedchem.5B01832  0.73
2015 Hamal S, D'huys T, Rowley WF, Vermeire K, Aquaro S, Frost BJ, Schols D, Bell TW. Metal complexes of pyridine-fused macrocyclic polyamines targeting the chemokine receptor CXCR4. Organic & Biomolecular Chemistry. 13: 10517-26. PMID 26338723 DOI: 10.1039/C5Ob01557J  0.8
2012 Bell TW, Demillo VG, Schols D, Vermeire K. Improving potencies and properties of CD4 down-modulating CADA analogs. Expert Opinion On Drug Discovery. 7: 39-48. PMID 22468892 DOI: 10.1517/17460441.2012.643865  0.797
2011 Demillo VG, Goulinet-Mateo F, Kim J, Schols D, Vermeire K, Bell TW. Unsymmetrical cyclotriazadisulfonamide (CADA) compounds as human CD4 receptor down-modulating agents. Journal of Medicinal Chemistry. 54: 5712-21. PMID 21800875 DOI: 10.1021/Jm2002603  0.812
2011 Scarbrough ED, Vermeire K, Schols D, Bell TW. Synthesis of Novel CADA Analog Prodrugs Designed as Down-Modulators of the CD4 Receptor Antiviral Research. 90: A75-A76. DOI: 10.1016/J.Antiviral.2011.03.163  0.43
2011 Bell TW, Demillo VG, Goulinet-Mateo F, Ali R, Pflug NC, Khan C, Vermeire K, Schols D. Effect of Molecular Symmetry on Potency in Novel Down-Modulators of the CD4 Receptor Antiviral Research. 90: A68. DOI: 10.1016/J.Antiviral.2011.03.140  0.787
2010 Jenabian MA, Saïdi H, Charpentier C, Bouhlal H, Schols D, Balzarini J, Bell TW, Vanham G, Bélec L. Differential activity of candidate microbicides against early steps of HIV-1 infection upon complement virus opsonization. Aids Research and Therapy. 7: 16. PMID 20546571 DOI: 10.1186/1742-6405-7-16  0.306
2010 Hamal S, Huskens D, Schols D, Bell T. Metal Complexes of Macrocyclic Polyamines Targeting the Cellular HIV Co-receptors, CXCR4 and CCR5 Antiviral Research. 86: A55-A56. DOI: 10.1016/J.Antiviral.2010.02.438  0.774
2010 Demillo V, Vermeire K, Schols D, Bell T. Unsymmetrical CADA Analogs as Novel Down-modulators of the CD4 Receptor Antiviral Research. 86: A53-A54. DOI: 10.1016/J.Antiviral.2010.02.432  0.793
2009 Vermeire K, Van Laethem K, Janssens W, Bell TW, Schols D. Human immunodeficiency virus type 1 escape from cyclotriazadisulfonamide-induced CD4-targeted entry inhibition is associated with increased neutralizing antibody susceptibility. Journal of Virology. 83: 9577-83. PMID 19570853 DOI: 10.1128/Jvi.00648-09  0.356
2009 Schols D, Hamal S, Cui L, Huskens D, Aquaro S, Bell T. Macrocyclic polyamines inhibit HIV infection by interacting with the cellular HIV co-receptors CXCR4 and CCR5 Retrovirology. 6. DOI: 10.1186/1742-4690-6-S2-P80  0.793
2009 Scarbrough E, Anugu S, Vermeire K, Schols D, Bell T. Synthesis of CADA Analog Prodrugs Designed as Novel Down-modulators of the CD4 Receptor Antiviral Research. 82: A63. DOI: 10.1016/J.Antiviral.2009.02.151  0.786
2008 Vermeire K, Brouwers J, Van Herrewege Y, Le Grand R, Vanham G, Augustijns P, Bell TW, Schols D. CADA, a potential anti-HIV microbicide that specifically targets the cellular CD4 receptor. Current Hiv Research. 6: 246-56. PMID 18473788 DOI: 10.1016/J.Antiviral.2009.02.161  0.429
2007 Vermeire K, Lisco A, Grivel JC, Scarbrough E, Dey K, Duffy N, Margolis L, Bell TW, Schols D. Design and cellular kinetics of dansyl-labeled CADA derivatives with anti-HIV and CD4 receptor down-modulating activity. Biochemical Pharmacology. 74: 566-78. PMID 17603023 DOI: 10.1016/J.Bcp.2007.05.018  0.662
2007 VERMEIRE K, LISCO A, GRIVEL J, BLANK P, SCHRAM V, DUFFY N, SCARBROUGH E, DEY K, BELL T, MARGOLIS L. Design and Cellular Kinetics of Dansyl-labeled CADA Derivatives with Specific Anti-HIV and CD4 Receptor Down-modulating Properties Antiviral Research. 74: A68-A69. DOI: 10.1016/J.Antiviral.2007.01.109  0.637
2007 ANUGU S, BELL T, DUFFY N, VERMEIRE K, SCHOLS D. Synthesis, Anti-HIV and CD4 Down-Modulation Activities of Novel CADA Compounds Antiviral Research. 74: A48-A48. DOI: 10.1016/J.Antiviral.2007.01.058  0.797
2006 Vermeire K, Schols D, Bell TW. Inhibitors of HIV infection via the cellular CD4 receptor. Current Medicinal Chemistry. 13: 731-43. PMID 16611063 DOI: 10.2174/092986706776055599  0.447
2006 Bell TW, Anugu S, Bailey P, Catalano VJ, Dey K, Drew MG, Duffy NH, Jin Q, Samala MF, Sodoma A, Welch WH, Schols D, Vermeire K. Synthesis and structure-activity relationship studies of CD4 down-modulating cyclotriazadisulfonamide (CADA) analogues. Journal of Medicinal Chemistry. 49: 1291-312. PMID 16480266 DOI: 10.1021/Jm0582524  0.802
2005 Barr JW, Bell TW, Catalano VJ, Cline JI, Phillips DJ, Procupez R. Syntheses, structures, and photoisomerization of (E)- and (Z)-2-tert-butyl-9-(2,2,2-triphenylethylidene)fluorene. The Journal of Physical Chemistry. A. 109: 11650-4. PMID 16366613 DOI: 10.1021/Jp054345L  0.3
2004 Bell TW, Hext NM. Supramolecular optical chemosensors for organic analytes. Chemical Society Reviews. 33: 589-98. PMID 15592624 DOI: 10.1039/B207182G  0.311
2004 Vermeire K, Princen K, Hatse S, De Clercq E, Dey K, Bell TW, Schols D. CADA, a novel CD4-targeted HIV inhibitor, is synergistic with various anti-HIV drugs in vitro. Aids (London, England). 18: 2115-25. PMID 15577644 DOI: 10.1097/00002030-200411050-00003  0.587
2004 Vermeire K, Schols D, Bell TW. CD4 down-modulating compounds with potent anti-HIV activity. Current Pharmaceutical Design. 10: 1795-803. PMID 15180541 DOI: 10.2174/1381612043384547  0.403
2003 Vermeire K, Bell TW, Choi HJ, Jin Q, Samala MF, Sodoma A, De Clercq E, Schols D. The Anti-HIV potency of cyclotriazadisulfonamide analogs is directly correlated with their ability to down-modulate the CD4 receptor. Molecular Pharmacology. 63: 203-10. PMID 12488553 DOI: 10.1124/Mol.63.1.203  0.461
2002 Vermeire K, Zhang Y, Princen K, Hatse S, Samala MF, Dey K, Choi HJ, Ahn Y, Sodoma A, Snoeck R, Andrei G, De Clercq E, Bell TW, Schols D. CADA inhibits human immunodeficiency virus and human herpesvirus 7 replication by down-modulation of the cellular CD4 receptor. Virology. 302: 342-53. PMID 12441078 DOI: 10.1006/Viro.2002.1624  0.626
2002 Bell TW, Khasanov AB, Drew MG. Role of pyridine hydrogen-bonding sites in recognition of basic amino acid side chains. Journal of the American Chemical Society. 124: 14092-103. PMID 12440908 DOI: 10.1021/Ja0273694  0.71
2002 Tamaru S, Shinkai S, Khasanov AB, Bell TW. Circular dichroism readout of sugar recognition in the cleft of a fused-pyridine receptor. Proceedings of the National Academy of Sciences of the United States of America. 99: 4972-6. PMID 11959949 DOI: 10.1073/Pnas.082638599  0.691
2002 Bell TW, Beckles DL, Debetta M, Glover BR, Hou Z, Hung KY, Khasanov AB. An improved preparation of 4-aminopyrimidine-5-carboxaldehyde Organic Preparations and Procedures International. 34: 321-325. DOI: 10.1080/00304940209356772  0.673
2001 Tamaru SI, Yamamoto M, Shinkai S, Khasanov AB, Bell TW. A hydrogen-bonding receptor that binds cationic monosaccharides with high affinity in methanol. Chemistry (Weinheim An Der Bergstrasse, Germany). 7: 5270-6. PMID 11822427 DOI: 10.1002/1521-3765(20011217)7:24<5270::Aid-Chem5270>3.0.Co;2-H  0.723
2001 Pilato ML, Catalano VJ, Bell TW. Synthesis of 1,2,3,4,5,6,7,8-octahydroacridine via condensation of cyclohexanone with formaldehyde. The Journal of Organic Chemistry. 66: 1525-7. PMID 11312996 DOI: 10.1021/Jo005746U  0.731
1999 Bell TW, Khasanov AB, Drew MG, Filikov A, James TL. A Small-Molecule Guanidinium Receptor: The Arginine Cork. Angewandte Chemie (International Ed. in English). 38: 2543-2547. PMID 10508332 DOI: 10.1002/(Sici)1521-3773(19990903)38:17<2543::Aid-Anie2543>3.0.Co;2-9  0.703
1999 Bell TW, Khasanov AB, Drew MGB, Filikov A, James TL. Ein kleiner Guanidinium-Rezeptor: der Arginin-Korken Angewandte Chemie. 111: 2705-2709. DOI: 10.1002/(Sici)1521-3757(19990903)111:17<2705::Aid-Ange2705>3.0.Co;2-6  0.663
1998 Bell TW, Hext NM, Khasanov AB. Binding biomolecules with designed, hydrogen-bonding receptors Pure and Applied Chemistry. 70: 2371-2377. DOI: 10.1351/Pac199870122371  0.701
1998 Bell TW, Cragg PJ, Firestone A, Kwok ADI, Liu J, Ludwig R, Sodoma A. Molecular Architecture. 2.1 Synthesis and Metal Complexation of Heptacyclic Terpyridyl Molecular Clefts Journal of Organic Chemistry. 63: 2232-2243. DOI: 10.1021/Jo9720041  0.355
1996 Bell TW, Heiss AM, Ludwig RT, Xiang C. An Effective Route to Highly Substituted Pyridines Synlett. 1996: 79-81. DOI: 10.1055/S-1996-5324  0.336
1992 Bell TW, Santora VJ. Complexation of benzamidinium by a new family of artificial receptors Journal of the American Chemical Society. 114: 8300-8302. DOI: 10.1021/Ja00047A057  0.323
1988 Bell TW, Liu J. Hexagonal lattice hosts for urea. A new series of designed heterocyclic receptors Journal of the American Chemical Society. 110: 3673-3674. DOI: 10.1021/Ja00219A060  0.318
1986 Bell TW, Meinwald J. Pheromones of two arctiid moths (Creatonotos transiens andC. gangis) : Chiral components from both sexes and achiral female components. Journal of Chemical Ecology. 12: 385-409. PMID 24306787 DOI: 10.1007/Bf01020563  0.509
1986 Wunderer H, Hansen K, Bell TW, Schneider D, Meinwald J. Sex pheromones of two Asian moths (Creatonotos transiens, C. gangis; Lepidoptera--Arctiidae): behavior, morphology, chemistry and electrophysiology. Experimental Biology. 46: 11-27. PMID 3817109  0.489
1984 Bell TW, Boppré M, Schneider D, Meinwald J. Stereochemical course of pheromone biosynthesis in the arctiid moth, Creatonotos transiens. Experientia. 40: 713-4. PMID 6540200 DOI: 10.1007/Bf01949738  0.509
1982 Schneider D, Boppré M, Zweig J, Horsley SB, Bell TW, Meinwald J, Hansen K, Diehl EW. Scent organ development in creatonotos moths: regulation by pyrrolizidine alkaloids. Science (New York, N.Y.). 215: 1264-5. PMID 17757544 DOI: 10.1126/Science.215.4537.1264  0.493
1981 Bell TW, Sondheimer F. Synthesis and wittig reaction of 1-(triphenylphosphoranylidene)-3-methoxy-2-propanone Journal of Organic Chemistry. 46: 217-219. DOI: 10.1021/Jo00314A060  0.44
1981 Bell TW. Synthesis and complexation properties of macrocyclic polyethers derived from chiral and meso-1,1′-bicyclohexyl-2,2′-diols Journal of the American Chemical Society. 103: 1163-1171. DOI: 10.1021/Ja00395A028  0.333
1980 Bell TW, Bowes CM, Sondheimer F. Structure and conformational isomerism of the major dimer of 2,3-naphthoquinodimethane Tetrahedron Letters. 21: 3299-3302. DOI: 10.1016/S0040-4039(00)78672-2  0.408
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