Wen-Lian Wu - Publications

Affiliations: 
Chemistry Ohio State University, Columbus, Columbus, OH 

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Wu WL, Burnett DA, Clader J, Greenlee WJ, Jiang Q, Hyde LA, Del Vecchio RA, Cohen-Williams ME, Song L, Lee J, Terracina G, Zhang Q, Nomeir A, Parker EM, Zhang L. Design and synthesis of water soluble β-aminosulfone analogues of SCH 900229 as γ-secretase inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 27836402 DOI: 10.1016/j.bmcl.2016.04.095  0.44
2016 Pissarnitski DA, Zhao Z, Cole D, Wu WL, Domalski M, Clader JW, Scapin G, Voigt J, Soriano A, Kelly T, Powles MA, Yao Z, Burnett DA. Scaffold-hopping from xanthines to tricyclic guanines: A case study of dipeptidyl peptidase 4 (DPP4) inhibitors. Bioorganic & Medicinal Chemistry. PMID 27670099 DOI: 10.1016/j.bmc.2016.09.007  0.88
2016 Wu WL, Hao J, Domalski M, Burnett DA, Pissarnitski D, Zhao Z, Stamford A, Scapin G, Gao YD, Soriano A, Kelly TM, Yao Z, Powles MA, Chen S, Mei H, et al. Discovery of Novel Tricyclic Heterocycles as Potent and Selective DPP-4 Inhibitors for the Treatment of Type 2 Diabetes. Acs Medicinal Chemistry Letters. 7: 498-501. PMID 27190600 DOI: 10.1021/acsmedchemlett.6b00027  0.88
2016 Wu W, Zhang L, Liu S, Ren H, Zhou X, Li H. Liquid-liquid phase transition in nano-confined silicon carbide. Journal of the American Chemical Society. PMID 26859609 DOI: 10.1021/jacs.5b13467  0.44
2016 Wu WH, Wang SW, Chen CC, Lai G. Mode identifiability of a cable-stayed bridge under different excitation conditions assessed with an improved algorithm based on stochastic subspace identification Smart Structures and Systems. 17: 363-389. DOI: 10.12989/sss.2016.17.3.363  0.44
2016 Chen X, Liu J, Weng S, Kong Y, Wu W, Zhang L, Li H. Structural geometry and kinematics of the Ailao Shan shear zone: Insights from integrated structural, microstructural, and fabric studies of the Yao Shan complex, Yunnan, Southwest China International Geology Review. 58: 849-873. DOI: 10.1080/00206814.2015.1136572  0.44
2016 Chen CC, Wu WH, Leu MR, Lai G. Tension determination of stay cable or external tendon with complicated constraints using multiple vibration measurements Measurement: Journal of the International Measurement Confederation. 86: 182-195. DOI: 10.1016/j.measurement.2016.02.053  0.44
2015 Zhao Z, Pissarnitski DA, Josien H, Wu WL, Xu R, Li H, Clader J, Burnett DA, Terracina G, Hyde L, Lee J, Song L, Zhang L. Discovery of a novel, potent spirocyclic series of γ-secretase inhibitors. Journal of Medicinal Chemistry. PMID 26496070 DOI: 10.1021/acs.jmedchem.5b00774  0.44
2015 Wu W, Guo H, Li X, Ferro-Famil L, Zhang L. Urban Land Use Information Extraction Using the Ultrahigh-Resolution Chinese Airborne SAR Imagery Ieee Transactions On Geoscience and Remote Sensing. 53: 5583-5599. DOI: 10.1109/TGRS.2015.2425658  0.44
2015 Chen CC, Wu WH, Tseng HZ, Chen CH, Lai G. Application of digital photogrammetry techniques in identifying the mode shape ratios of stay cables with multiple camcorders Measurement: Journal of the International Measurement Confederation. 75: 134-146. DOI: 10.1016/j.measurement.2015.07.037  0.44
2013 Wu WL, Sasikumar TK, Domalski MS, Qiang L, Burnett DA, Clader J, Greenlee WJ, Chan TM, Lee J, Zhang L. A-ring modification of SCH 900229 and related chromene sulfone γ-secretase inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 850-3. PMID 23265902 DOI: 10.1016/j.bmcl.2012.11.054  0.88
2013 Wu WL, Asberom T, Bara T, Bennett C, Burnett DA, Clader J, Domalski M, Greenlee WJ, Josien H, McBriar M, Rajagopalan M, Vicarel M, Xu R, Hyde LA, Del Vecchio RA, et al. Structure activity relationship studies of tricyclic bispyran sulfone γ-secretase inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 844-9. PMID 23265892 DOI: 10.1016/j.bmcl.2012.11.047  0.88
2012 Wu WL, Domalski M, Burnett DA, Josien H, Bara T, Rajagopalan M, Xu R, Clader J, Greenlee WJ, Brunskill A, Hyde LA, Del Vecchio RA, Cohen-Williams ME, Song L, Lee J, et al. Discovery of SCH 900229, a Potent Presenilin 1 Selective γ-Secretase Inhibitor for the Treatment of Alzheimer's Disease. Acs Medicinal Chemistry Letters. 3: 892-6. PMID 24900404 DOI: 10.1021/ml300044f  0.88
2012 Brumfield S, Korakas P, Silverman LS, Tulshian D, Matasi JJ, Qiang L, Bennett CE, Burnett DA, Greenlee WJ, Knutson CE, Wu WL, Sasikumar TK, Domalski M, Bertorelli R, Grilli M, et al. Synthesis and SAR development of novel mGluR1 antagonists for the treatment of chronic pain. Bioorganic & Medicinal Chemistry Letters. 22: 7223-6. PMID 23084894 DOI: 10.1016/j.bmcl.2012.09.048  0.88
2012 Bennett CE, Burnett DA, Greenlee WJ, Knutson CE, Korakas P, Li C, Tulshian D, Wu WL, Bertorelli R, Fredduzzi S, Grilli M, Lozza G, Reggiani A, Veltri A. Fused tricyclic mGluR1 antagonists for the treatment of neuropathic pain. Bioorganic & Medicinal Chemistry Letters. 22: 1575-8. PMID 22266036 DOI: 10.1016/j.bmcl.2011.12.131  0.88
2012 Wu WL, Cheng CF, Sun WH, Wong CW, Chen CC. Targeting ASIC3 for pain, anxiety, and insulin resistance. Pharmacology & Therapeutics. 134: 127-38. PMID 22233754 DOI: 10.1016/j.pharmthera.2011.12.009  0.44
2011 Xu R, Cole D, Asberom T, Bara T, Bennett C, Burnett DA, Clader J, Domalski M, Greenlee WJ, Hyde L, Josien H, Li H, McBriar M, McKittrick B, Pissarnitski D, ... ... Wu WL, et al. SAR of tricyclic sulfones as γ-secretase inhibitors Science China Chemistry. 54: 1688-1701. DOI: 10.1007/s11426-011-4388-6  0.88
2010 Sasikumar TK, Burnett DA, Asberom T, Wu WL, Bennett C, Cole D, Xu R, Greenlee WJ, Clader J, Zhang L, Hyde L. Tetracyclic sulfones as potent gamma-secretase inhibitors: synthesis and structure-activity relationship studies. Bioorganic & Medicinal Chemistry Letters. 20: 3645-8. PMID 20471254 DOI: 10.1016/j.bmcl.2010.04.103  0.88
2010 Xu R, Cole D, Asberom T, Bara T, Bennett C, Burnett DA, Clader J, Domalski M, Greenlee W, Hyde L, Josien H, Li H, McBriar M, McKittrick B, McPhail AT, ... ... Wu WL, et al. Design and synthesis of tricyclic sulfones as gamma-secretase inhibitors with greatly reduced Notch toxicity. Bioorganic & Medicinal Chemistry Letters. 20: 2591-6. PMID 20236824 DOI: 10.1016/j.bmcl.2010.02.080  0.88
2009 Wu WL, Zhang L. γ-secretase inhibitors for the treatment of alzheimer's disease Drug Development Research. 70: 94-100. DOI: 10.1002/ddr.20288  0.88
2007 Wu WL, Burnett DA, Domalski M, Greenlee WJ, Li C, Bertorelli R, Fredduzzi S, Lozza G, Veltri A, Reggiani A. Discovery of orally efficacious tetracyclic metabotropic glutamate receptor 1 (mGluR1) antagonists for the treatment of chronic pain. Journal of Medicinal Chemistry. 50: 5550-3. PMID 17929793 DOI: 10.1021/jm070590c  0.88
2006 Sasikumar TK, Qiang L, Wu WL, Burnett DA, Greenlee WJ, O'Neill K, Hawes BE, van Heek M, Graziano M. Tetrahydroisoquinolines as MCH-R1 antagonists. Bioorganic & Medicinal Chemistry Letters. 16: 4917-21. PMID 16824753 DOI: 10.1016/j.bmcl.2006.06.055  0.88
2006 Wu WL, Burnett DA, Caplen MA, Domalski MS, Bennett C, Greenlee WJ, Hawes BE, O'Neill K, Weig B, Weston D, Spar B, Kowalski T. Design and synthesis of orally efficacious benzimidazoles as melanin-concentrating hormone receptor 1 antagonists. Bioorganic & Medicinal Chemistry Letters. 16: 3674-8. PMID 16690315 DOI: 10.1016/j.bmcl.2006.04.062  0.88
2006 Wu WL, Burnett DA, Spring R, Qiang L, Sasikumar TK, Domalski MS, Greenlee WJ, O'Neill K, Hawes BE. Synthesis and structure-activity relationships of piperidine-based melanin-concentrating hormone receptor 1 antagonists. Bioorganic & Medicinal Chemistry Letters. 16: 3668-73. PMID 16690312 DOI: 10.1016/j.bmcl.2006.04.061  0.88
2005 Wu WL, Burnett DA, Spring R, Greenlee WJ, Smith M, Favreau L, Fawzi A, Zhang H, Lachowicz JE. Dopamine D1/D5 receptor antagonists with improved pharmacokinetics: design, synthesis, and biological evaluation of phenol bioisosteric analogues of benzazepine D1/D5 antagonists. Journal of Medicinal Chemistry. 48: 680-93. PMID 15689153 DOI: 10.1021/jm030614p  0.88
2002 Wu WL, Caplen MA, Domalski MS, Zhang H, Fawzi A, Burnett DA. Synthesis and structure-activity relationships of aminoalkylazetidines as ORL1 receptor ligands. Bioorganic & Medicinal Chemistry Letters. 12: 3157-60. PMID 12372523 DOI: 10.1016/S0960-894X(02)00652-2  0.88
2001 Wu YL, Wu WL, Yao ZJ, Li YL, Wang YF, Li JC, Sun XL, Peng ZH, Yu Q, Hu TS, Zeng BB, Wang XZ. Syntheses of chiral pure natural products from carbohydrates Chinese Journal of Organic Chemistry. 21: 1051-1059.  0.88
1998 Gao Y, Wu WL, Wu YL, Ye B, Zhou R. A straightforward synthetic approach to the spiroketal-enol ethers synthesis of natural antifeeding compound tonghaosu and its analogs Tetrahedron. 54: 12523-12538.  0.88
1997 Hart DJ, Li J, Wu WL, Kozikowski AP. Applications of organosulfur chemistry to organic synthesis: Total synthesis of (+)-himbeline and (+)-himbacine Journal of Organic Chemistry. 62: 5023-5033. DOI: 10.1021/jo970612a  0.88
1996 Hart DJ, Wu WL. Observations regarding the first step of the Julia-Lythgoe olefin synthesis Tetrahedron Letters. 37: 5283-5286. DOI: 10.1016/0040-4039(96)01092-1  0.88
1996 Gao Y, Wu WL, Ye B, Zhou R, Wu YL. Convenient syntheses of tonghaosu and two thiophene substituted spiroketal enol ether natural products Tetrahedron Letters. 37: 893-896. DOI: 10.1016/0040-4039(95)02311-9  0.88
1996 Peng ZH, Li YL, Wu WL, Liu CX, Wu YL. Synthesis of (2E,4E)-dienals by double formyl-olefination with an arsonium salt and its application in the syntheses of lipoxygenase metabolites of arachidonic acid Journal of the Chemical Society - Perkin Transactions 1. 1057-1066.  0.88
1996 Wu YL, Wu WL, Li YL, Sun XL, Peng ZH. Stereoselective synthesis of acyclic natural products containing chiral vicinal diol Pure and Applied Chemistry. 68: 727-734.  0.88
1995 Hart DJ, Wu WL, Kozikowski AP. Total syntheses of (+)-himbacine and (+)-himbeline Journal of the American Chemical Society. 117: 9369-9370. DOI: 10.1021/ja00141a036  0.88
1995 Wu WL, Yao ZJ, Li YL, Li JC, Xia Y, Wu YL. Diastereoselective propargylation of α-alkoxy aldehydes with propargyl bromide and zinc. A versatile and efficient method for the synthesis of chiral oxygenated acyclic natural products The Journal of Organic Chemistry. 60: 3257-3259.  0.88
1993 Wu WL, Wu YL. Formal syntheses of hepoxilin B3, trioxilin B3 and substances against rice blast disease from D-mannitol Journal of the Chemical Society, Chemical Communications. 821-822. DOI: 10.1039/C39930000821  0.88
1993 Wu WL, Wu YL. Stereoselective synthesis of methyl (11S,12S,13S)-(9Z,15Z)-11-hydroxy-12,13-epoxy octadecadienoate from D-mannose Tetrahedron. 49: 4665-4670. DOI: 10.1016/S0040-4020(01)81295-3  0.88
1993 Wu WL, Wu YL. A concise synthesis of the methyl esters of (10S)-hepoxilin B3 and (10S)-trioxilin B3 Journal of Organic Chemistry. 58: 2760-2762.  0.88
1993 Wu WL, Wu YL. Chemoselective hydrolysis of terminal isopropylidene acetals and subsequent glycol cleavage by periodic acid in one pot Journal of Organic Chemistry. 58: 3586-3588.  0.88
1993 Wu WL, Wu YL. Formal syntheses of hepoxilin B3, trioxilin B3 and substances effective against rice blast disease and total syntheses of 11(R),12(S),13(S)-tri-hydroxyoctadeca-9(Z),15(Z)-dienoic acid Journal of the Chemical Society, Perkin Transactions 1. 3081-3086.  0.88
1992 Wu WL, Wu YL. Synthesis of (10R)-hepoxilin B3 methyl ester and (10R)-trioxilin B3 methyl ester Journal of the Chemical Society, Perkin Transactions 1. 2705-2707. DOI: 10.1039/P19920002705  0.88
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