Leslie N. Aldrich - Publications

Affiliations: 
2006-2008 Chemistry Mercer University, Macon, GA, United States 

14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Gerlach EM, Korkmaz MA, Pavlinov I, Gao Q, Aldrich LN. Systematic diversity-oriented synthesis of reduced flavones from γ-pyrones to probe biological performance diversity. Acs Chemical Biology. PMID 31184855 DOI: 10.1021/acschembio.9b00294  0.52
2018 Pavlinov I, Gerlach EM, Aldrich LN. Next generation diversity-oriented synthesis: a paradigm shift from chemical diversity to biological diversity. Organic & Biomolecular Chemistry. PMID 30328455 DOI: 10.1039/c8ob02327a  0.52
2018 Young AN, Herrera D, Huntsman AC, Korkmaz MA, Lantvit DD, Mazumder S, Kolli S, Coss CC, King S, Wang H, Swanson SM, Kinghorn AD, Zhang X, Phelps MA, Aldrich LN, et al. Phyllanthusmin derivatives induce apoptosis and reduce tumor burden in high grade serous ovarian cancer by late-stage autophagy inhibition. Molecular Cancer Therapeutics. PMID 30018048 DOI: 10.1158/1535-7163.MCT-17-1195  0.52
2018 Helgren TR, Xu LL, Sotelo D, Mehta YR, Korkmaz MA, Pavlinov I, Aldrich L. Microwave-assisted, asymmetric synthesis of 3-amino-2,3-dihydrobenzofuran flavonoid derivatives from chalcones. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29446184 DOI: 10.1002/chem.201705984  0.52
2015 Kuo SY, Castoreno AB, Aldrich LN, Lassen KG, Goel G, Dan?ík V, Kuballa P, Latorre I, Conway KL, Sarkar S, Maetzel D, Jaenisch R, Clemons PA, Schreiber SL, Shamji AF, et al. Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics. Proceedings of the National Academy of Sciences of the United States of America. PMID 26195741 DOI: 10.1073/pnas.1512289112  0.8
2015 Khor B, Gagnon JD, Goel G, Roche MI, Conway KL, Tran K, Aldrich LN, Sundberg TB, Paterson AM, Mordecai S, Dombkowski D, Schirmer M, Tan PH, Bhan AK, Roychoudhuri R, et al. The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells. Elife. 4. PMID 25998054 DOI: 10.7554/eLife.05920  0.8
2015 Aldrich LN, Kuo SY, Castoreno AB, Goel G, Kuballa P, Rees MG, Seashore-Ludlow BA, Cheah JH, Latorre IJ, Schreiber SL, Shamji AF, Xavier RJ. Discovery of a Small-Molecule Probe for V-ATPase Function. Journal of the American Chemical Society. 137: 5563-8. PMID 25860544 DOI: 10.1021/jacs.5b02150  0.8
2013 Aldrich LN, Berry CB, Bates BS, Konkol LC, So M, Lindsley CW. Towards the Total Synthesis of Marineosin A: Construction of the Macrocyclic Pyrrole and an Advanced, Functionalized Spiroaminal Model. European Journal of Organic Chemistry. 2013. PMID 24415906 DOI: 10.1002/ejoc.201300643  0.8
2013 Shaw SY, Tran K, Castoreno AB, Peloquin JM, Lassen KG, Khor B, Aldrich LN, Tan PH, Graham DB, Kuballa P, Goel G, Daly MJ, Shamji AF, Schreiber SL, Xavier RJ. Selective modulation of autophagy, innate immunity, and adaptive immunity by small molecules. Acs Chemical Biology. 8: 2724-33. PMID 24168452 DOI: 10.1021/cb400352d  0.8
2013 Conway KL, Kuballa P, Song JH, Patel KK, Castoreno AB, Yilmaz OH, Jijon HB, Zhang M, Aldrich LN, Villablanca EJ, Peloquin JM, Goel G, Lee IA, Mizoguchi E, Shi HN, et al. Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection. Gastroenterology. 145: 1347-57. PMID 23973919 DOI: 10.1053/j.gastro.2013.08.035  0.8
2013 Panarese JD, Konkol LC, Berry CB, Bates BS, Aldrich LN, Lindsley CW. Spiroaminal Model Systems of the Marineosins with Final Step Pyrrole Incorporation. Tetrahedron Letters. 54: 2231-2234. PMID 23606772 DOI: 10.1016/j.tetlet.2013.02.059  0.8
2010 Aldrich LN, Stoops SL, Crews BC, Marnett LJ, Lindsley CW. Total synthesis and biological evaluation of tambjamine K and a library of unnatural analogs. Bioorganic & Medicinal Chemistry Letters. 20: 5207-11. PMID 20655217 DOI: 10.1016/j.bmcl.2010.06.154  0.8
2010 Aldrich LN, Dawson ES, Lindsley CW. Evaluation of the biosynthetic proposal for the synthesis of marineosins A and B. Organic Letters. 12: 1048-51. PMID 20141121 DOI: 10.1021/ol100034p  0.8
2009 Aldrich LN, Lebois EP, Lewis LM, Nalywajko NT, Niswender CM, Weaver CD, Conn PJ, Lindsley CW. MAOS ls for the general synthesis and lead optimization of 3,6-disubstituted-[1,2,4]triazolo[4,3-b]pyridazines. Tetrahedron Letters. 50: 212-215. PMID 22090663 DOI: 10.1016/j.tetlet.2008.10.127  0.8
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