D. Borden Lacy, Ph.D. - Related publications

Affiliations: 
1990-1994 University of North Carolina, Chapel Hill, Chapel Hill, NC 
 1994-1999 University of California, Berkeley, Berkeley, CA 
 1999- Vanderbilt University, Nashville, TN 
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Huang Y, Jin F, Funato Y, Xu Z, Zhu W, Wang J, Sun M, Zhao Y, Yu Y, Miki H, Hattori M. Structural basis for the Mg recognition and regulation of the CorC Mg transporter. Science Advances. 7. PMID 33568487 DOI: 10.1126/sciadv.abe6140   
2021 Elgamoudi BA, Andrianova EP, Shewell LK, Day CJ, King RM, Taha, Rahman H, Hartley-Tassell LE, Zhulin IB, Korolik V. The chemoreceptor Tlp10 has a bimodal ligand-binding domain and specificity for multiple classes of chemoeffectors. Science Signaling. 14. PMID 33402336 DOI: 10.1126/scisignal.abc8521   
2021 Liauw BW, Afsari HS, Vafabakhsh R. Conformational rearrangement during activation of a metabotropic glutamate receptor. Nature Chemical Biology. PMID 33398167 DOI: 10.1038/s41589-020-00702-5   
2021 Mohd-Kipli F, Claridge JK, Habjanič J, Jiang A, Schnell JR. Conformational triggers associated with influenza matrix protein 1 polymerization. The Journal of Biological Chemistry. 100316. PMID 33516724 DOI: 10.1016/j.jbc.2021.100316   
2021 Kolodny R, Nepomnyachiy S, Tawfik DS, Ben-Tal N. Bridging themes: short protein segments found in different architectures. Molecular Biology and Evolution. PMID 33502503 DOI: 10.1093/molbev/msab017   
2021 Xu X, Zhang D, Zhou B, Zhen X, Ouyang S. Structural and biochemical analyses of the tetrameric cell binding domain of Lys170 from enterococcal phage F170/08. European Biophysics Journal : Ebj. PMID 33609147 DOI: 10.1007/s00249-021-01511-x   
2021 Kato M, Tu BP, McKnight SL. Redox-mediated regulation of low complexity domain self-association. Current Opinion in Genetics & Development. 67: 111-118. PMID 33454579 DOI: 10.1016/j.gde.2020.12.006   
2021 Dietrich MH, Chan LJ, Adair A, Keremane S, Pymm P, Lo AW, Cao YC, Tham WH. Nanobody generation and structural characterization of Plasmodium falciparum 6-cysteine protein Pf12p. The Biochemical Journal. PMID 33480416 DOI: 10.1042/BCJ20200415   
2021 He J, Han Z, Farooq QUA, Li C. Study on functional sites in human multidrug resistance protein 1 (hMRP1). Proteins. PMID 33469960 DOI: 10.1002/prot.26049   
2021 Sharma A, Kumari S, Goel M. Uncovering the structure-function aspects of an archaeal CsaA protein. Biochimica Et Biophysica Acta. Proteins and Proteomics. 140615. PMID 33561579 DOI: 10.1016/j.bbapap.2021.140615   
2021 Aiyer S, Swapna GVT, Ma LC, Liu G, Hao J, Chalmers G, Jacobs BC, Montelione GT, Roth MJ. A common binding motif in the ET domain of BRD3 forms polymorphic structural interfaces with host and viral proteins. Structure (London, England : 1993). PMID 33592170 DOI: 10.1016/j.str.2021.01.010   
2021 Feng W, Nguyen H, Shen D, Deng H, Jiang Z, Podolnikova N, Ugarova T, Wang X. Structural Characterization of the Interaction between the αI-Domain of the Integrin Mac-1 (αβ) and the Cytokine Pleiotrophin. Biochemistry. PMID 33427449 DOI: 10.1021/acs.biochem.0c00700   
2021 Chaoprasid P, Lukat P, Mühlen S, Heidler T, Gazdag EM, Dong S, Bi W, Rüter C, Kirchenwitz M, Steffen A, Jänsch L, Stradal TEB, Dersch P, Blankenfeldt W. Crystal structure of bacterial cytotoxic necrotizing factor CNF reveals molecular building blocks for intoxication. The Embo Journal. e105202. PMID 33410511 DOI: 10.15252/embj.2020105202   
2021 Qin W, Yu F, Zhou H, Li P, Zhou F, Li HJ, He CX, Xing L, Zhou X, Zhao D, Li PQ, Jin X, Wang QS, He JH, Cao HL. Complex crystal structure determination and anti-non-small-cell lung cancer activity of the Hsp90 inhibitor Debio0932. Acta Crystallographica. Section D, Structural Biology. 77: 86-97. PMID 33404528 DOI: 10.1107/S2059798320014990   
2021 Preethi D, Anishetty S, Gautam P. Molecular dynamics study of in silico mutations in the auto-inhibitory loop of human endothelial nitric oxide synthase FMN sub-domain. Journal of Molecular Modeling. 27: 63. PMID 33527205 DOI: 10.1007/s00894-020-04643-7   
2021 Tőke O, Koprivanacz K, Radnai L, Merő B, Juhász T, Liliom K, Buday L. Solution NMR Structure of the SH3 Domain of Human Caskin1 Validates the Lack of a Typical Peptide Binding Groove and Supports a Role in Lipid Mediator Binding. Cells. 10. PMID 33467043 DOI: 10.3390/cells10010173   
2021 van Sorge NM, Bonsor DA, Deng L, Lindahl E, Schmitt V, Lyndin M, Schmidt A, Nilsson OR, Brizuela J, Boero E, Sundberg EJ, van Strijp JAG, Doran KS, Singer BB, Lindahl G, et al. Bacterial protein domains with a novel Ig-like fold target human CEACAM receptors. The Embo Journal. e106103. PMID 33522633 DOI: 10.15252/embj.2020106103   
2021 Zhang Y, Greer RA, Song Y, Praveen H, Song Y. In silico identification of available drugs targeting cell surface BiP to disrupt SARS-CoV-2 binding and replication: Drug repurposing approach. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 105771. PMID 33617948 DOI: 10.1016/j.ejps.2021.105771   
2021 Mori T, Jung J, Kobayashi C, Dokainish HM, Re S, Sugita Y. Elucidation of Interactions Regulating Conformational Stability and Dynamics of SARS-CoV-2 S-Protein. Biophysical Journal. PMID 33484712 DOI: 10.1016/j.bpj.2021.01.012   
2021 Gupta D, Tiwari P, Haque MA, Sachdeva E, Hassan MI, Ethayathulla AS, Kaur P. Structural insights into the transient closed conformation and pH dependent ATPase activity of S.Typhi GyraseB N- terminal domain. Archives of Biochemistry and Biophysics. 108786. PMID 33548211 DOI: 10.1016/j.abb.2021.108786   
2021 Rostøl JT, Xie W, Kuryavyi V, Maguin P, Kao K, Froom R, Patel DJ, Marraffini LA. The Card1 nuclease provides defence during type-III CRISPR immunity. Nature. PMID 33461211 DOI: 10.1038/s41586-021-03206-x   
2021 Tran TH, Chan AH, Young LC, Bindu L, Neale C, Messing S, Dharmaiah S, Taylor T, Denson JP, Esposito D, Nissley DV, Stephen AG, McCormick F, Simanshu DK. KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation. Nature Communications. 12: 1176. PMID 33608534 DOI: 10.1038/s41467-021-21422-x   
2021 Lin KF, Fry MY, Saladi SM, Clemons WM. Molecular basis of tail-anchored integral membrane protein recognition by the cochaperone Sgt2. The Journal of Biological Chemistry. 100441. PMID 33610544 DOI: 10.1016/j.jbc.2021.100441   
2021 Iacobucci GJ, Wen H, Helou M, Liu B, Zheng W, Popescu GK. Cross-subunit interactions that stabilize open states mediate gating in NMDA receptors. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33384330 DOI: 10.1073/pnas.2007511118   
2021 Wang X, Ma Q. Wzb of Vibrio vulnificus represents a new group of low molecular weight protein tyrosine phosphatases with a unique insertion in the W-loop. The Journal of Biological Chemistry. 100280. PMID 33450227 DOI: 10.1016/j.jbc.2021.100280   
2021 Dalal V, Dhankhar P, Singh V, Singh V, Rakhaminov G, Golemi-Kotra D, Kumar P. Structure-Based Identification of Potential Drugs Against FmtA of Staphylococcus aureus: Virtual Screening, Molecular Dynamics, MM-GBSA, and QM/MM. The Protein Journal. PMID 33421024 DOI: 10.1007/s10930-020-09953-6   
2021 Feinberg H, Jégouzo SAF, Lasanajak Y, Smith DF, Drickamer K, Weis WI, Taylor ME. Structural analysis of carbohydrate binding by the macrophage mannose receptor CD206. The Journal of Biological Chemistry. 100368. PMID 33545173 DOI: 10.1016/j.jbc.2021.100368   
2021 Barber NM, Lau CKY, Turner L, Watson G, Thrane S, Lusingu JPA, Lavstsen T, Higgins MK. Structure-Guided Design of a Synthetic Mimic of an Endothelial Protein C Receptor-Binding PfEMP1 Protein. Msphere. 6. PMID 33408232 DOI: 10.1128/mSphere.01081-20   
2021 Magnussen HM, Huang DT. Identification of a catalytic active but non-aggregating MDM2 RING domain variant. Journal of Molecular Biology. 166807. PMID 33450248 DOI: 10.1016/j.jmb.2021.166807   
2021 Fry MY, Saladi SM, Clemons WM. The STI1-domain is a flexible alpha-helical fold with a hydrophobic groove. Protein Science : a Publication of the Protein Society. PMID 33620121 DOI: 10.1002/pro.4049   
2021 Lin MH, Cho CC, Chiu YC, Chien CY, Huang YP, Chang CF, Hsu CH. Elucidating the tunability of binding behavior for the MERS-CoV macro domain with NAD metabolites. Communications Biology. 4: 123. PMID 33504944 DOI: 10.1038/s42003-020-01633-6   
2021 Susa KJ, Rawson S, Kruse AC, Blacklow SC. Cryo-EM structure of the B cell co-receptor CD19 bound to the tetraspanin CD81. Science (New York, N.Y.). 371: 300-305. PMID 33446559 DOI: 10.1126/science.abd9836   
2021 Hubbard PA, Xia C, Shen AL, Kim JP. Structural and kinetic investigations of the carboxy terminus of NADPH cytochrome P450 oxidoreductase. Archives of Biochemistry and Biophysics. 108792. PMID 33556357 DOI: 10.1016/j.abb.2021.108792   
2021 Slater A, Di Y, Clark JC, Jooss NJ, Martin EM, Alenazy FO, Thomas MR, Ariëns RA, Herr AB, Poulter NS, Emsley J, Watson SP. Structural characterisation of a novel GPVI nanobody-complex reveals a biologically active domain-swapped GPVI dimer. Blood. PMID 33512486 DOI: 10.1182/blood.2020009440   
2021 Romero-Tamayo S, Laplaza R, Velazquez-Campoy A, Villanueva R, Medina M, Ferreira P. W196 and the -Hairpin Motif Modulate the Redox Switch of Conformation and the Biomolecular Interaction Network of the Apoptosis-Inducing Factor. Oxidative Medicine and Cellular Longevity. 2021: 6673661. PMID 33510840 DOI: 10.1155/2021/6673661   
2021 Ortega-Alarcon D, Claveria-Gimeno R, Vega S, Jorge-Torres OC, Esteller M, Abian O, Velazquez-Campoy A. Influence of the disordered domain structure of MeCP2 on its structural stability and dsDNA interaction. International Journal of Biological Macromolecules. 175: 58-66. PMID 33548325 DOI: 10.1016/j.ijbiomac.2021.01.206   
2021 Millan CR, Francis M, Kumar Khandelwal N, Thompson VF, Thaker TM, Tomasiak TM. A conserved motif in intracellular loop 1 stabilizestheoutward-facing conformation of TmrAB. Journal of Molecular Biology. 166834. PMID 33524413 DOI: 10.1016/j.jmb.2021.166834   
2021 Ping YQ, Mao C, Xiao P, Zhao RJ, Jiang Y, Yang Z, An WT, Shen DD, Yang F, Zhang H, Qu C, Shen Q, Tian C, Li ZJ, Li S, et al. Structures of the glucocorticoid-bound adhesion receptor GPR97-G complex. Nature. PMID 33408414 DOI: 10.1038/s41586-020-03083-w   
2021 Pastor M, Czapinska H, Helbrecht I, Krakowska K, Lutz T, Xu SY, Bochtler M. Crystal structures of the EVE-HNH endonuclease VcaM4I in the presence and absence of DNA. Nucleic Acids Research. PMID 33450012 DOI: 10.1093/nar/gkaa1218   
2021 Deng Z, Yuan B, Yang K. Cardiolipin Selectively Binds to the Interface of SemiSWEET and Regulates Its Dimerization. The Journal of Physical Chemistry Letters. 1940-1946. PMID 33591759 DOI: 10.1021/acs.jpclett.1c00022   
2021 Young EC, Baumgartner JT, Karatan E, Kuhn ML. A mutagenic screen reveals NspS residues important for regulation of biofilm formation. Microbiology (Reading, England). PMID 33502310 DOI: 10.1099/mic.0.001023   
2021 Dang TKL, Nguyen T, Habeck M, Gültas M, Waack S. A graph-based algorithm for detecting rigid domains in protein structures. Bmc Bioinformatics. 22: 66. PMID 33579190 DOI: 10.1186/s12859-021-03966-3   
2021 Sundaram R, Manohar K, Patel SK, Acharya N, Vasudevan D. Structural analyses of PCNA from the fungal pathogen Candida albicans identify three regions with species-specific conformations. Febs Letters. PMID 33544878 DOI: 10.1002/1873-3468.14055   
2021 Salvi N, Bessa LM, Guseva S, Camacho-Zarco A, Maurin D, Perez LM, Malki A, Hengesbach M, Korn SM, Schlundt A, Schwalbe H, Blackledge M. H, C and N backbone chemical shift assignments of SARS-CoV-2 nsp3a. Biomolecular Nmr Assignments. PMID 33475934 DOI: 10.1007/s12104-020-10001-8   
2021 Song G, Luo BH. Effects of the association of the α β lower legs on integrin ligand binding. Journal of Cellular Biochemistry. PMID 33619784 DOI: 10.1002/jcb.29912   
2021 Fujimoto Z, Hong LTT, Kishine N, Suzuki N, Kimura K. Tetramer formation of Bacillus subtilis YabJ protein that belongs to YjgF/YER057c/UK114 family. Bioscience, Biotechnology, and Biochemistry. PMID 33590041 DOI: 10.1093/bbb/zbaa037   
2021 Mondal B, Nagesh J, Reddy G. Double Domain Swapping in Human γC and γD Crystallin Drives Early Stages of Aggregation. The Journal of Physical Chemistry. B. PMID 33566611 DOI: 10.1021/acs.jpcb.0c07833   
2021 Taghon GJ, Rowe JB, Kapolka NJ, Isom DG. Predictable cholesterol binding sites in GPCRs lack consensus motifs. Structure (London, England : 1993). PMID 33508215 DOI: 10.1016/j.str.2021.01.004   
2021 Tomlinson CWE, Cornish KAS, Whiting A, Pohl E. Structure-functional relationship of cellular retinoic acid-binding proteins I and II interacting with natural and synthetic ligands. Acta Crystallographica. Section D, Structural Biology. 77: 164-175. PMID 33559606 DOI: 10.1107/S2059798320015247   
2021 Gonti S, Westler WM, Miyagi M, Bann JG. Site-Specific Labeling and F NMR Provide Direct Evidence for Dynamic Behavior of the Anthrax Toxin Pore ϕ-Clamp Structure. Biochemistry. PMID 33428379 DOI: 10.1021/acs.biochem.0c00833