Michael A. Hanson, Ph.D. - Publications

Affiliations: 
1998-2002 Scripps Research Institute 
 2009-2014 Receptos 
 2014- GPCR Consortium 

74 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Wu F, Yang L, Hang K, Laursen M, Wu L, Han GW, Ren Q, Roed NK, Lin G, Hanson MA, Jiang H, Wang MW, Reedtz-Runge S, Song G, Stevens RC. Full-length human GLP-1 receptor structure without orthosteric ligands. Nature Communications. 11: 1272. PMID 32152292 DOI: 10.1038/s41467-020-14934-5  1
2019 Claff T, Yu J, Blais V, Patel N, Martin C, Wu L, Han GW, Holleran BJ, Van der Poorten O, White KL, Hanson MA, Sarret P, Gendron L, Cherezov V, Katritch V, et al. Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists. Science Advances. 5: eaax9115. PMID 31807708 DOI: 10.1126/sciadv.aax9115  1
2019 Munk C, Mutt E, Isberg V, Nikolajsen LF, Bibbe JM, Flock T, Hanson MA, Stevens RC, Deupi X, Gloriam DE. An online resource for GPCR structure determination and analysis. Nature Methods. PMID 30664776 DOI: 10.1038/s41592-018-0302-x  1
2018 Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, ... ... Hanson MA, et al. Publisher Correction: Crystal structure of misoprostol bound to the labor inducer prostaglandin E receptor. Nature Chemical Biology. PMID 30573766 DOI: 10.1038/s41589-018-0214-1  1
2018 Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, ... ... Hanson MA, et al. Crystal structure of misoprostol bound to the labor inducer prostaglandin E receptor. Nature Chemical Biology. PMID 30510194 DOI: 10.1038/s41589-018-0160-y  1
2018 Qin S, Meng M, Yang D, Bai W, Lu Y, Peng Y, Song G, Wu Y, Zhou Q, Zhao S, Huang X, McCorvy JD, Cai X, Dai A, Roth BL, ... Hanson MA, et al. High-throughput identification of G protein-coupled receptor modulators through affinity mass spectrometry screening. Chemical Science. 9: 3192-3199. PMID 29732102 DOI: 10.1039/c7sc04698g  1
2018 Peng Y, McCorvy JD, Harpsøe K, Lansu K, Yuan S, Popov P, Qu L, Pu M, Che T, Nikolajsen LF, Huang XP, Wu Y, Shen L, Bjørn-Yoshimoto WE, Ding K, ... ... Hanson MA, et al. 5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology. Cell. PMID 29398112 DOI: 10.1016/j.cell.2018.01.001  1
2018 Zhang H, Qiao A, Yang L, Van Eps N, Frederiksen KS, Yang D, Dai A, Cai X, Zhang H, Yi C, Cao C, He L, Yang H, Lau J, Ernst OP, ... Hanson MA, et al. Structure of the glucagon receptor in complex with a glucagon analogue. Nature. 553: 106-110. PMID 29300013 DOI: 10.1038/nature25153  1
2017 Hua T, Vemuri K, Nikas SP, Laprairie RB, Wu Y, Qu L, Pu M, Korde A, Jiang S, Ho JH, Han GW, Ding K, Li X, Liu H, Hanson MA, et al. Crystal structures of agonist-bound human cannabinoid receptor CB1. Nature. PMID 28678776 DOI: 10.1038/nature23272  1
2017 Ma Y, Yue Y, Ma Y, Zhang Q, Zhou Q, Song Y, Shen Y, Li X, Ma X, Li C, Hanson MA, Han GW, Sickmier EA, Swaminath G, Zhao S, et al. Structural Basis for Apelin Control of the Human Apelin Receptor. Structure (London, England : 1993). PMID 28528775 DOI: 10.1016/j.str.2017.04.008  1
2017 Zhang H, Qiao A, Yang D, Yang L, Dai A, de Graaf C, Reedtz-Runge S, Dharmarajan V, Zhang H, Han GW, Grant TD, Sierra RG, Weierstall U, Nelson G, Liu W, ... ... Hanson MA, et al. Structure of the full-length glucagon class B G-protein-coupled receptor. Nature. PMID 28514451 DOI: 10.1038/nature22363  1
2017 Song G, Yang D, Wang Y, de Graaf C, Zhou Q, Jiang S, Liu K, Cai X, Dai A, Lin G, Liu D, Wu F, Wu Y, Zhao S, Ye L, ... ... Hanson MA, et al. Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators. Nature. PMID 28514449 DOI: 10.1038/nature22378  1
2017 Zhang X, Zhao F, Wu Y, Yang J, Han GW, Zhao S, Ishchenko A, Ye L, Lin X, Ding K, Dharmarajan V, Griffin PR, Gati C, Nelson G, Hunter MS, ... Hanson MA, et al. Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand. Nature Communications. 8: 15383. PMID 28513578 DOI: 10.1038/ncomms15383  1
2016 Hua T, Vemuri K, Pu M, Qu L, Han GW, Wu Y, Zhao S, Shui W, Li S, Korde A, Laprairie RB, Stahl EL, Ho JH, Zvonok N, Zhou H, ... ... Hanson MA, et al. Crystal Structure of the Human Cannabinoid Receptor CB1. Cell. 167: 750-762.e14. PMID 27768894 DOI: 10.1016/j.cell.2016.10.004  1
2016 Yang D, de Graaf C, Yang L, Song G, Dai A, Cai X, Feng Y, Reedtz-Runge S, Hanson MA, Yang H, Jiang H, Stevens RC, Wang MW. Structural Determinants of Binding the Seven-transmembrane Domain of the Glucagon-like Peptide-1 Receptor. The Journal of Biological Chemistry. PMID 27059958 DOI: 10.1074/jbc.M116.721977  1
2015 Chrencik JE, Roth CB, Terakado M, Kurata H, Omi R, Kihara Y, Warshaviak D, Nakade S, Asmar-Rovira G, Mileni M, Mizuno H, Griffith MT, Rodgers C, Han GW, Velasquez J, ... ... Hanson MA, et al. Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1. Cell. 161: 1633-43. PMID 26091040 DOI: 10.1016/j.cell.2015.06.002  1
2014 Hanson MA, Peach R. Structural biology of the S1P1 receptor. Current Topics in Microbiology and Immunology. 378: 23-53. PMID 24728592 DOI: 10.1007/978-3-319-05879-5_2  1
2013 Rosen H, Stevens RC, Hanson M, Roberts E, Oldstone MB. Sphingosine-1-phosphate and its receptors: structure, signaling, and influence. Annual Review of Biochemistry. 82: 637-62. PMID 23527695 DOI: 10.1146/annurev-biochem-062411-130916  1
2012 Chun E, Thompson AA, Liu W, Roth CB, Griffith MT, Katritch V, Kunken J, Xu F, Cherezov V, Hanson MA, Stevens RC. Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors. Structure (London, England : 1993). 20: 967-76. PMID 22681902 DOI: 10.1016/j.str.2012.04.010  1
2012 Hanson MA, Roth CB, Jo E, Griffith MT, Scott FL, Reinhart G, Desale H, Clemons B, Cahalan SM, Schuerer SC, Sanna MG, Han GW, Kuhn P, Rosen H, Stevens RC. Crystal structure of a lipid G protein-coupled receptor. Science (New York, N.Y.). 335: 851-5. PMID 22344443 DOI: 10.1126/science.1215904  1
2011 Xu F, Liu W, Hanson MA, Stevens RC, Cherezov V. Development of an Automated High Throughput LCP-FRAP Assay to Guide Membrane Protein Crystallization in Lipid Mesophases. Crystal Growth & Design. 11: 1193-1201. PMID 21660116 DOI: 10.1021/cg101385e  1
2010 Chien EY, Liu W, Zhao Q, Katritch V, Han GW, Hanson MA, Shi L, Newman AH, Javitch JA, Cherezov V, Stevens RC. Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist. Science (New York, N.Y.). 330: 1091-5. PMID 21097933 DOI: 10.1126/science.1197410  1
2010 Liu W, Hanson MA, Stevens RC, Cherezov V. LCP-Tm: an assay to measure and understand stability of membrane proteins in a membrane environment. Biophysical Journal. 98: 1539-48. PMID 20409473 DOI: 10.1016/j.bpj.2009.12.4296  1
2010 Thanh GL, Abbenante G, Adamson G, Becker B, Clark C, Condie G, Falzun T, Grathwohl M, Gupta P, Hanson M, Huynh N, Katavic P, Kuipers K, Lam A, Liu L, et al. A versatile synthetic approach toward diversity libraries using monosaccharide scaffolds. The Journal of Organic Chemistry. 75: 197-203. PMID 19961235 DOI: 10.1021/jo9021919  1
2009 Hanson MA, Brorson KA, Moreira AR, Rao G. Comparisons of optically monitored small-scale stirred tank vessels to optically controlled disposable bag bioreactors. Microbial Cell Factories. 8: 44. PMID 19656387 DOI: 10.1186/1475-2859-8-44  1
2009 Hanson MA, Stevens RC. Retraction: Cocrystal structure of synaptobrevin-II bound to botulinum neurotoxin type B at 2.0 A resolution. Nature Structural & Molecular Biology. 16: 795. PMID 19578378 DOI: 10.1038/nsmb0709-795  1
2009 Cherezov V, Hanson MA, Griffith MT, Hilgart MC, Sanishvili R, Nagarajan V, Stepanov S, Fischetti RF, Kuhn P, Stevens RC. Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 microm size X-ray synchrotron beam. Journal of the Royal Society, Interface / the Royal Society. 6: S587-97. PMID 19535414 DOI: 10.1098/rsif.2009.0142.focus  1
2009 Katritch V, Reynolds KA, Cherezov V, Hanson MA, Roth CB, Yeager M, Abagyan R. Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes. Journal of Molecular Recognition : Jmr. 22: 307-18. PMID 19353579 DOI: 10.1002/jmr.949  1
2009 Hanson MA, Stevens RC. Discovery of new GPCR biology: one receptor structure at a time. Structure (London, England : 1993). 17: 8-14. PMID 19141277 DOI: 10.1016/j.str.2008.12.003  1
2009 Weis WI, Rosenbaum DM, Rasmussen SGF, Choi HJ, Thian FS, Kobilka TS, Yao XJ, Day PW, Parnot C, Fung JJ, Ratnala VRP, Kobilka BK, Cherezov V, Hanson MA, Kuhn P, et al. Crystal structures of the β2-adrenergic receptor Nato Science For Peace and Security Series a: Chemistry and Biology. 217-230. DOI: 10.1007/978-90-481-2339-1-14  1
2009 Weis WI, Rosenbaum DM, Rasmussen SGF, Choi HJ, Thian FS, Kobilka TS, Yao XJ, Day PW, Parnot C, Fung JJ, Ratnala VRP, Kobilka BK, Cherezov V, Hanson MA, Kuhn P, et al. Crystal structures of the β2-adrenergic receptor Nato Science For Peace and Security Series a: Chemistry and Biology. 217-230.  1
2009 Rao G, Kostov Y, Moreira A, Frey D, Hanson M, Jornitz M, Reif OW, Baumfalk R, Qualitz J. Non-invasive sensors as enablers of "smart" disposables Bioprocess International. 7: 24-27.  1
2008 Cherezov V, Liu J, Griffith M, Hanson MA, Stevens RC. LCP-FRAP Assay for Pre-Screening Membrane Proteins for in Meso Crystallization. Crystal Growth & Design. 8: 4307-4315. PMID 19234616 DOI: 10.1021/cg800778j  1
2008 Jaakola VP, Griffith MT, Hanson MA, Cherezov V, Chien EY, Lane JR, Ijzerman AP, Stevens RC. The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist. Science (New York, N.Y.). 322: 1211-7. PMID 18832607 DOI: 10.1126/science.1164772  1
2008 Lute S, Norling L, Hanson M, Emery R, Stinson D, Padua K, Blank G, Chen Q, Brorson K. Robustness of virus removal by protein A chromatography is independent of media lifetime Journal of Chromatography A. 1205: 17-25. PMID 18722622 DOI: 10.1016/j.chroma.2008.07.094  1
2008 Asmar-Rovira GA, Asseo-García AM, Quesada O, Hanson MA, Cheng A, Nogueras C, Lasalde-Dominicci JA, Stevens RC. Biophysical and ion channel functional characterization of the Torpedo californica nicotinic acetylcholine receptor in varying detergent-lipid environments. The Journal of Membrane Biology. 223: 13-26. PMID 18581036 DOI: 10.1007/s00232-008-9107-7  1
2008 Hanson MA, Cherezov V, Griffith MT, Roth CB, Jaakola VP, Chien EY, Velasquez J, Kuhn P, Stevens RC. A specific cholesterol binding site is established by the 2.8 A structure of the human beta2-adrenergic receptor. Structure (London, England : 1993). 16: 897-905. PMID 18547522 DOI: 10.1016/j.str.2008.05.001  1
2008 Szmacinski H, Smith DS, Hanson MA, Kostov Y, Lakowicz JR, Rao G. A novel method for monitoring monoclonal antibody production during cell culture. Biotechnology and Bioengineering. 100: 448-57. PMID 18438872 DOI: 10.1002/bit.21795  1
2008 Alexandrov AI, Mileni M, Chien EY, Hanson MA, Stevens RC. Microscale fluorescent thermal stability assay for membrane proteins. Structure (London, England : 1993). 16: 351-9. PMID 18334210 DOI: 10.1016/j.str.2008.02.004  1
2008 Roth CB, Hanson MA, Stevens RC. Stabilization of the human beta2-adrenergic receptor TM4-TM3-TM5 helix interface by mutagenesis of Glu122(3.41), a critical residue in GPCR structure. Journal of Molecular Biology. 376: 1305-19. PMID 18222471 DOI: 10.1016/j.jmb.2007.12.028  1
2008 Szmacinski H, Smith D, Hanson MA, Rao G, Lakowicz JR. Measurement and monitoring of the production of proteins during cell culture using plasmonic structures Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6869. DOI: 10.1117/12.778490  1
2007 Cherezov V, Rosenbaum DM, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Kuhn P, Weis WI, Kobilka BK, Stevens RC. High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor. Science (New York, N.Y.). 318: 1258-65. PMID 17962520 DOI: 10.1126/science.1150577  1
2007 Rosenbaum DM, Cherezov V, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Yao XJ, Weis WI, Stevens RC, Kobilka BK. GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function. Science (New York, N.Y.). 318: 1266-73. PMID 17962519 DOI: 10.1126/science.1150609  1
2007 Hanson MA, Brooun A, Baker KA, Jaakola VP, Roth C, Chien EY, Alexandrov A, Velasquez J, Davis L, Griffith M, Moy K, Ganser-Pornillos BK, Hua Y, Kuhn P, Ellis S, et al. Profiling of membrane protein variants in a baculovirus system by coupling cell-surface detection with small-scale parallel expression. Protein Expression and Purification. 56: 85-92. PMID 17723307 DOI: 10.1016/j.pep.2007.06.003  1
2007 Hanson MA, Ge X, Kostov Y, Brorson KA, Moreira AR, Rao G. Comparisons of optical pH and dissolved oxygen sensors with traditional electrochemical probes during mammalian cell culture. Biotechnology and Bioengineering. 97: 833-41. PMID 17216654 DOI: 10.1002/bit.21320  1
2006 Ge X, Hanson M, Shen H, Kostov Y, Brorson KA, Frey DD, Moreira AR, Rao G. Validation of an optical sensor-based high-throughput bioreactor system for mammalian cell culture. Journal of Biotechnology. 122: 293-306. PMID 16423420 DOI: 10.1016/j.jbiotec.2005.12.009  1
2005 Arndt JW, Gu J, Jaroszewski L, Schwarzenbacher R, Hanson MA, Lebeda FJ, Stevens RC. The structure of the neurotoxin-associated protein HA33/A from Clostridium botulinum suggests a reoccurring beta-trefoil fold in the progenitor toxin complex. Journal of Molecular Biology. 346: 1083-93. PMID 15701519 DOI: 10.1016/j.jmb.2004.12.039  1
2005 Earl GW, Weisshaar DE, Paulson D, Hanson M, Uilk J, Wineinger D, Moeckly S. Quaternary methyl carbonates: Novel agents for fabric conditioning Journal of Surfactants and Detergents. 8: 325-329.  1
2004 Asmar GA, Hanson MA, Ward AB, Lasalde JA, Stevens RC, Potter C, Kuhn P. Low-Voltage Electron Microscopy (LVEM) as a probe for solubilized membrane protein aggregation states Microscopy and Microanalysis. 10: 1492-1493. DOI: 10.1017/S1431927604886069  1
2002 Bracey MH, Hanson MA, Masuda KR, Stevens RC, Cravatt BF. Structural adaptations in a membrane enzyme that terminates endocannabinoid signaling. Science (New York, N.Y.). 298: 1793-6. PMID 12459591 DOI: 10.1126/science.1076535  1
2001 Rupp B, Segelke B, Stevens R, Hanson M. Questions about the structure of the botulinum neurotoxin B light chain in complex with a target peptide Nature Structural Biology. 8: 663-664. PMID 11473252  1
2000 Orencia MC, Hanson MA, Stevens RC. Structural analysis of affinity matured antibodies and laboratory-evolved enzymes. Advances in Protein Chemistry. 55: 227-59. PMID 11050935  1
2000 Hanson MA, Stevens RC. Cocrystal structure of synaptobrevin-II bound to botulinum neurotoxin type B at 2.0 A resolution. Nature Structural Biology. 7: 687-92. PMID 10932255 DOI: 10.1038/77997  1
2000 Mundorff EC, Hanson MA, Varvak A, Ulrich H, Schultz PG, Stevens RC. Conformational effects in biological catalysis: an antibody-catalyzed oxy-cope rearrangement. Biochemistry. 39: 627-32. PMID 10651626 DOI: 10.1021/bi9924314  1
2000 Hanson MA, Oost TK, Sukonpan C, Rich DH, Stevens RC. Structural basis for BABIM inhibition of botulinum neurotoxin type B protease [22] Journal of the American Chemical Society. 122: 11268-11269. DOI: 10.1021/ja005533m  1
1997 Hanson M, Unger KK. Evaluation of advanced silica packings, part II: Application of nonporous silica particles in HPLC Lc Gc: Liquid Chromatography, Gas Chromatography. 15: 364-368.  1
1997 Hanson M, Unger KK. Evaluation of advanced silica packings, Part I: Synthesis and characterzation of nonporous silica particles for HPLC Lc Gc: Liquid Chromatography, Gas Chromatography. 15: 170-178.  1
1996 Hanson M, Unger KK, Mant CT, Hodges RS. Optimization strategies in ultrafast reversed-phase chromatography of proteins Trac - Trends in Analytical Chemistry. 15: 102-110. DOI: 10.1016/0165-9936(96)80766-7  1
1996 Hanson M. Micropreparative supercritical fluid chromatography as a bench-scale method for steroid purification Lc Gc: Liquid Chromatography, Gas Chromatography. 14: 152-158.  1
1996 Hanson M, Unger KK. Evaluation of advanced silica packings: Part II: Application of non-porous silica particles in HPLC Lc Gc Europe. 9: 741-746.  1
1996 Hanson M, Unger KK. Evaluation of advanced silica packings: Part 1: Synthesis and characterization of non-porous silica particles for HPLC Lc Gc Europe. 9: 650-656.  1
1995 Hanson M. Aspects of retention behaviour of steroids in packed column supercritical fluid chromatography Chromatographia. 40: 58-68. DOI: 10.1007/BF02274609  1
1995 Hanson M. Small-scale preparative supercritical fluid chromatography of cyproterone acetate Chromatographia. 40: 139-142. DOI: 10.1007/BF02272161  1
1994 Hanson M, Unger KK, Denoyel R, Rouquerol J. Interactions of lysozyme with hydrophilic and hydrophobic polymethacrylate stationary phases in reversed phase chromatography (RPC) Journal of Biochemical and Biophysical Methods. 29: 283-294. PMID 7699205 DOI: 10.1016/0165-022X(94)90039-6  1
1994 Hanson M. Selectivity changes towards steroids in packed column supercritical fluid chromatography (SFC) induced by temperature and pressure variation Chromatographia. 39: 431-437. DOI: 10.1007/BF02278758  1
1994 Hanson M, Kabbara J, Junghans K. Packed column supercritical fluid chromatography with FID: Investigation of products from copper-catalyzed conjugate additions of trimethylaluminium to α, β-unsaturated aldehydes Chromatographia. 39: 299-305. DOI: 10.1007/BF02274517  1
1993 Hanson M, Kurganov A, Unger KK, Davankov VA. Polymer-coated reversed-phase packings in high-performance liquid chromatography Journal of Chromatography A. 656: 369-380. DOI: 10.1016/0021-9673(93)80810-U  1
1993 Hanson M, Eray B, Unger K, Neimark AV, Schmid J, Albert K, Bayer E. A model for polybutadiene coatings on porous silica Chromatographia. 35: 403-409. DOI: 10.1007/BF02278594  1
1993 Neimark AV, Hanson M, Unger KK. Fractal analysis of the distribution of high-viscosity fluids in porous supports Journal of Physical Chemistry. 97: 6011-6015.  1
1993 Hanson M. Effect of the chain mobility of polymeric reversed-phase stationary phases on polypeptide retention Analytical Chemistry. 65: 2249-2253.  1
1992 Hanson M, Unger KK. Polymer coatings as stationary phases in high-performance liquid chromatography Trends in Analytical Chemistry. 11: 368-373. DOI: 10.1016/0165-9936(92)80026-3  1
1992 Hanson M, Unger KK, Mant CT, Hodges RS. Polymer-coated reversed-phase packings with controlled hydrophobic properties. II. Effect on the selectivity of peptide separations Journal of Chromatography A. 599: 77-85. DOI: 10.1016/0021-9673(92)85460-B  1
1992 Hanson M, Unger KK, Mant CT, Hodges RS. Polymer-coated reversed-phase packings with controlled hydrophobic properties. I. Effect on the selectivity of protein separations Journal of Chromatography A. 599: 65-75. DOI: 10.1016/0021-9673(92)85459-7  1
1990 Hanson M, Unger KK, Schomburg G. Non-porous polybutadiene-coated silicas as stationary phases in reversed-phase chromatography Journal of Chromatography A. 517: 269-284. DOI: 10.1016/S0021-9673(01)95727-9  1
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