Jim Porter - Publications

Affiliations: 
2002 Boston College, Newton, MA, United States 

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Palacino J, Swalley SE, Song C, Cheung AK, Shu L, Zhang X, Van Hoosear M, Shin Y, Chin DN, Keller CG, Beibel M, Renaud NA, Smith TM, Salcius M, Shi X, ... ... Porter JA, et al. Corrigendum: SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice. Nature Chemical Biology. 11: 741. PMID 26284678 DOI: 10.1038/nchembio0915-741a  0.64
2015 Palacino J, Swalley SE, Song C, Cheung AK, Shu L, Zhang X, Van Hoosear M, Shin Y, Chin DN, Keller CG, Beibel M, Renaud NA, Smith TM, Salcius M, Shi X, ... ... Porter JA, et al. SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice. Nature Chemical Biology. 11: 511-7. PMID 26030728 DOI: 10.1038/nchembio.1837  0.64
2013 Winkler DG, Faia KL, DiNitto JP, Ali JA, White KF, Brophy EE, Pink MM, Proctor JL, Lussier J, Martin CM, Hoyt JG, Tillotson B, Murphy EL, Lim AR, Thomas BD, ... ... Porter JR, et al. PI3K-δ and PI3K-γ inhibition by IPI-145 abrogates immune responses and suppresses activity in autoimmune and inflammatory disease models. Chemistry & Biology. 20: 1364-74. PMID 24211136 DOI: 10.1016/j.chembiol.2013.09.017  1
2010 Porter JR, Fritz CC, Depew KM. Discovery and development of Hsp90 inhibitors: a promising pathway for cancer therapy. Current Opinion in Chemical Biology. 14: 412-20. PMID 20409745 DOI: 10.1016/j.cbpa.2010.03.019  1
2010 Porter JR, Adams J, Ahn R, Ammoscato V, Arsenault B, Austad BC, Baker G, Basuki J, Booth MR, Campbell MJ, Carter B, Curtis M, Depew K, Douglas MA, Ge J, et al. Pharmaceutical development of IPI-504, an Hsp90 inhibitor and clinical candidate for the treatment of cancer Drug Development Research. 71: 429-438. DOI: 10.1002/ddr.20383  1
2009 Douglas M, Lim AR, Porter JR, West K, Pink MM, Ge J, Wylie AA, Tibbits TT, Biggs K, Curtis M, Palombella VJ, Adams J, Fritz CC, Normant E. The antiproliferative activity of the heat shock protein 90 inhibitor IPI-504 is not dependent on NAD(P)H:quinone oxidoreductase 1 activity in vivo. Molecular Cancer Therapeutics. 8: 3369-78. PMID 19952119 DOI: 10.1158/1535-7163.MCT-09-0568  1
2009 Porter JR, Ge J, Lee J, Normant E, West K. Ansamycin inhibitors of Hsp90: nature's prototype for anti-chaperone therapy. Current Topics in Medicinal Chemistry. 9: 1386-418. PMID 19860734 DOI: 10.2174/156802609789895719  1
2008 Tremblay MR, Nevalainen M, Nair SJ, Porter JR, Castro AC, Behnke ML, Yu LC, Hagel M, White K, Faia K, Grenier L, Campbell MJ, Cushing J, Woodward CN, Hoyt J, et al. Semisynthetic cyclopamine analogues as potent and orally bioavailable hedgehog pathway antagonists. Journal of Medicinal Chemistry. 51: 6646-9. PMID 18842035 DOI: 10.1021/jm8008508  1
2006 Sydor JR, Normant E, Pien CS, Porter JR, Ge J, Grenier L, Pak RH, Ali JA, Dembski MS, Hudak J, Patterson J, Penders C, Pink M, Read MA, Sang J, et al. Development of 17-allylamino-17-demethoxygeldanamycin hydroquinone hydrochloride (IPI-504), an anti-cancer agent directed against Hsp90. Proceedings of the National Academy of Sciences of the United States of America. 103: 17408-13. PMID 17090671 DOI: 10.1073/pnas.0608372103  1
2006 Ge J, Normant E, Porter JR, Ali JA, Dembski MS, Gao Y, Georges AT, Grenier L, Pak RH, Patterson J, Sydor JR, Tibbitts TT, Tong JK, Adams J, Palombella VJ. Design, synthesis, and biological evaluation of hydroquinone derivatives of 17-amino-17-demethoxygeldanamycin as potent, water-soluble inhibitors of Hsp90. Journal of Medicinal Chemistry. 49: 4606-15. PMID 16854066 DOI: 10.1021/jm0603116  1
2005 Akullian LC, Porter JR, Traverse JF, Snapper ML, Hoveyda AH. Asymmetric synthesis of acyclic amines through Zr- and Hf-catalyzed enantioselective alkylzinc reagents to imines Advanced Synthesis and Catalysis. 347: 417-425. DOI: 10.1002/adsc.200404319  1
2004 Kurosu M, Porter JR, Foley MA. An efficient synthesis of indane-derived bis(oxazoline) and its application to hetero Diels-Alder reactions on polymer support Tetrahedron Letters. 45: 145-148. DOI: 10.1016/j.tetlet.2003.10.097  1
2002 Limanto J, Tallarico JA, Porter JR, Khuong KS, Houk KN, Snapper ML. Intramolecular cycloadditions of cyclobutadiene with olefins. Journal of the American Chemical Society. 124: 14748-58. PMID 12465988 DOI: 10.1021/ja0203162  1
2001 Porter JR, Traverse JF, Hoveyda AH, Snapper ML. Three-component catalytic asymmetric synthesis of aliphatic amines. Journal of the American Chemical Society. 123: 10409-10. PMID 11604001 DOI: 10.1021/ja0118744  1
2001 Porter JR, Traverse JF, Hoveyda AH, Snapper ML. Enantioselective synthesis of arylamines through Zr-catalyzed addition of dialkylzincs to imines. Reaction development by screening of parallel libraries. Journal of the American Chemical Society. 123: 984-5. PMID 11456637 DOI: 10.1021/ja003747y  1
2000 Porter JR, Wirschun WG, Kuntz KW, Snapper ML, Hoveyda AH. Ti-catalyzed regio- and enantioselective synthesis of unsaturated α- amino nitriles, amides, and acids. Catalyst identification through screening of parallel libraries [7] Journal of the American Chemical Society. 122: 2657-2658. DOI: 10.1021/ja994121e  1
1999 Porter JR, Snapper ML. Formation of carbon-carbon bonds using iron tricarbonyl-(η4- cyclobutadienyl)-stabilized carbonium ions Synthesis. 1407-1410.  1
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