Ryan P. Murelli, Ph.D. - Publications

2010- Chemistry CUNY Brooklyn, New York, NY, United States 

30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Hirsch DR, Metrano AJ, Stone EA, Storch G, Miller SJ, Murelli RP. Troponoid Atropisomerism: Studies on the Configurational Stability of Tropone-Amide Chiral Axes. Organic Letters. PMID 30869521 DOI: 10.1021/acs.orglett.9b00707  0.76
2018 Cao F, Orth C, Donlin MJ, Adegboyega P, Meyers MJ, Murelli RP, Elagawany M, Elgendy B, Tavis JE. Synthesis and Evaluation of Troponoids as a New Class of Antibiotics. Acs Omega. 3: 15125-15133. PMID 30533576 DOI: 10.1021/acsomega.8b01754  0.48
2018 Miller JT, Zhao H, Masaoka T, Varnado B, Cornejo Castro EM, Marshall VA, Kouhestani K, Lynn AY, Aron KE, Xia A, Beutler JA, Hirsch DR, Tang L, Whitby D, Murelli RP, et al. Sensitivity of the C-terminal nuclease domain of Kaposi's sarcoma-associated herpesvirus ORF29 to two classes of active site ligands. Antimicrobial Agents and Chemotherapy. PMID 30061278 DOI: 10.1128/AAC.00233-18  0.76
2018 Tavis JE, Zoidis G, Meyers MJ, Murelli RP. Chemical Approaches to Inhibiting the Hepatitis B Virus Ribonuclease H. Acs Infectious Diseases. PMID 29565562 DOI: 10.1021/acsinfecdis.8b00045  0.48
2018 D'Erasmo MP, Murelli RP. Fluorous-Phase Approach to α-Hydroxytropolone Synthesis. The Journal of Organic Chemistry. PMID 29338231 DOI: 10.1021/acs.joc.7b03032  0.76
2017 Fuhr KN, Hirsch DR, Murelli RP, Brenner-Moyer SE. Catalytic Enantioselective Intermolecular [5 + 2] Dipolar Cycloadditions of a 3-Hydroxy-4-pyrone-Derived Oxidopyrylium Ylide. Organic Letters. PMID 29148809 DOI: 10.1021/acs.orglett.7b03196  0.76
2017 Long KR, Lomonosova E, Li Q, Ponzar NL, Villa JA, Touchette E, Rapp S, Liley RM, Murelli RP, Grigoryan A, Buller RM, Wilson L, Bial J, Sagartz JE, Tavis JE. Efficacy of hepatitis B virus ribonuclease H inhibitors, a new class of replication antagonists, in FRG human liver chimeric mice. Antiviral Research. PMID 29129708 DOI: 10.1016/j.antiviral.2017.11.008  0.48
2017 Lomonosova E, Daw J, Garimallaprabhakaran AK, Agyemang NB, Ashani Y, Murelli RP, Tavis JE. Efficacy and cytotoxicity in cell culture of novel α-hydroxytropolone inhibitors of Hepatitis B virus ribonuclease H. Antiviral Research. PMID 28633989 DOI: 10.1016/j.antiviral.2017.06.014  0.48
2017 Donlin MJ, Zunica A, Lipnicky A, Garimallaprabhakaran AK, Berkowitz AJ, Grigoryan A, Meyers MJ, Tavis JE, Murelli RP. Troponoids can inhibit growth of the human fungal pathogen Cryptococcus neoformans. Antimicrobial Agents and Chemotherapy. PMID 28167553 DOI: 10.1128/AAC.02574-16  0.48
2016 Murelli RP, D'Erasmo MP, Hirsch DR, Meck C, Masaoka T, Wilson JA, Zhang B, Pal RK, Gallicchio E, Beutler JA, Le Grice SF. Synthetic α-Hydroxytropolones as Inhibitors of HIV Reverse Transcriptase Ribonuclease H Activity. Medchemcomm. 7: 1783-1788. PMID 28093576 DOI: 10.1039/C6MD00238B  1
2016 D'Erasmo MP, Masaoka T, Wilson JA, Hunte EM, Beutler JA, Le Grice SF, Murelli RP. Traceless Solid-Phase α-Hydroxytropolone Synthesis. Medchemcomm. 7: 1789-1792. PMID 28090282 DOI: 10.1039/C6MD00237D  0.76
2016 Zhang B, D'Erasmo MP, Murelli RP, Gallicchio E. Free Energy-Based Virtual Screening and Optimization of RNase H Inhibitors of HIV-1 Reverse Transcriptase. Acs Omega. 1: 435-447. PMID 27713931 DOI: 10.1021/acsomega.6b00123  0.76
2016 D'Erasmo MP, Meck C, Lewis CA, Murelli RP. Discovery and Development of a Three-Component Oxidopyrylium [5+2] Cycloaddition. The Journal of Organic Chemistry. PMID 27018974 DOI: 10.1021/acs.joc.6b00394  1
2016 Masaoka T, Zhao H, Hirsch DR, D'Erasmo MP, Meck C, Varnado B, Gupta A, Meyers MJ, Baines J, Beutler JA, Murelli RP, Tang L, Le Grice SF. Characterization of the C-Terminal Nuclease Domain of Herpes Simplex Virus pUL15 as a Target of Nucleotidyltransferase Inhibitors. Biochemistry. PMID 26829613 DOI: 10.1021/acs.biochem.5b01254  1
2016 Ireland PJ, Tavis JE, D'Erasmo MP, Hirsch DR, Murelli RP, Cadiz MM, Patel BS, Gupta AK, Edwards TC, Korom M, Moran EA, Morrison LA. Synthetic α-hydroxytropolones inhibit replication of wild-type and acyclovir-resistant herpes simplex viruses. Antimicrobial Agents and Chemotherapy. PMID 26787704 DOI: 10.1128/AAC.02675-15  1
2015 Lu G, Lomonosova E, Cheng X, Moran EA, Meyers MJ, Le Grice SF, Thomas CJ, Jiang JK, Meck C, Hirsch DR, D'Erasmo MP, Suyabatmaz DM, Murelli RP, Tavis JE. Hydroxylated tropolones inhibit hepatitis B virus replication by blocking viral ribonuclease H activity. Antimicrobial Agents and Chemotherapy. 59: 1070-9. PMID 25451058 DOI: 10.1128/AAC.04617-14  1
2014 Hirsch DR, Cox G, D'Erasmo MP, Shakya T, Meck C, Mohd N, Wright GD, Murelli RP. Inhibition of the ANT(2")-Ia resistance enzyme and rescue of aminoglycoside antibiotic activity by synthetic α-hydroxytropolones. Bioorganic & Medicinal Chemistry Letters. 24: 4943-7. PMID 25283553 DOI: 10.1016/j.bmcl.2014.09.037  1
2014 Meck C, D'Erasmo MP, Hirsch DR, Murelli RP. The biology and synthesis of α-hydroxytropolones. Medchemcomm. 5: 842-852. PMID 25089179 DOI: 10.1039/C4MD00055B  1
2014 D'Erasmo MP, Smith WB, Munoz A, Mohandas P, Au AS, Marineau JJ, Quadri LE, Bradner JE, Murelli RP. 7,9-Diaryl-1,6,8-trioxaspiro[4.5]dec-3-en-2-ones: readily accessible and highly potent anticancer compounds. Bioorganic & Medicinal Chemistry Letters. 24: 4035-8. PMID 25011911 DOI: 10.1016/j.bmcl.2014.05.102  1
2013 Williams YD, Meck C, Mohd N, Murelli RP. Triflic acid-mediated rearrangements of 3-methoxy-8-oxabicyclo[3.2.1]octa-3,6-dien-2-ones: synthesis of methoxytropolones and furans. The Journal of Organic Chemistry. 78: 11707-13. PMID 24171600 DOI: 10.1021/jo401617r  1
2012 Munoz A, Murelli RP. Acid-mediated coupling of γ-hydroxybutenolides and aldehydes: Synthesis of a new class of spirocyclic ketal-lactones. Tetrahedron Letters. 53: 6779-6781. PMID 23335822 DOI: 10.1016/j.tetlet.2012.09.139  1
2012 Meck C, Mohd N, Murelli RP. An oxidopyrylium cyclization/ring-opening route to polysubstituted α-hydroxytropolones. Organic Letters. 14: 5988-91. PMID 23167954 DOI: 10.1021/ol302892g  1
2010 Nelson JW, Chamessian AG, McEnaney PJ, Murelli RP, Kazmierczak BI, Kazmiercak BI, Spiegel DA. A biosynthetic strategy for re-engineering the Staphylococcus aureus cell wall with non-native small molecules. Acs Chemical Biology. 5: 1147-55. PMID 20923200 DOI: 10.1021/cb100195d  1
2010 Zhang AX, Murelli RP, Barinka C, Michel J, Cocleaza A, Jorgensen WL, Lubkowski J, Spiegel DA. A remote arene-binding site on prostate specific membrane antigen revealed by antibody-recruiting small molecules. Journal of the American Chemical Society. 132: 12711-6. PMID 20726553 DOI: 10.1021/ja104591m  1
2009 Stern E, Jay SM, Demento SL, Murelli RP, Reed MA, Malinski T, Spiegel DA, Mooney DJ, Fahmy TM. Spatiotemporal control over molecular delivery and cellular encapsulation from electropolymerized micro- and nanopatterned surfaces. Advanced Functional Materials. 19: 2888-2895. PMID 20445826 DOI: 10.1002/adfm.200900307  1
2009 Murelli RP, Zhang AX, Michel J, Jorgensen WL, Spiegel DA. Chemical control over immune recognition: a class of antibody-recruiting small molecules that target prostate cancer. Journal of the American Chemical Society. 131: 17090-2. PMID 19888723 DOI: 10.1021/ja906844e  1
2008 Murelli RP, Catalán S, Gannon MP, Snapper ML. Ruthenium-catalyzed tandem enyne-cross metathesis-cyclopropanation: three-component access to vinyl cyclopropanes Tetrahedron Letters. 49: 5714-5717. DOI: 10.1016/j.tetlet.2008.07.119  1
2007 Murelli RP, Snapper ML. Ruthenium-catalyzed tandem cross-metathesis/Wittig olefination: generation of conjugated dienoic esters from terminal olefins. Organic Letters. 9: 1749-52. PMID 17397176 DOI: 10.1021/ol070445t  1
2007 Murelli RP, Cheung AK, Snapper ML. Conformationally restricted (+)-cacospongionolide B analogues. Influence on secretory phospholipase A2 inhibition. The Journal of Organic Chemistry. 72: 1545-52. PMID 17315974 DOI: 10.1021/jo061407a  1
2004 Cheung AK, Murelli R, Snapper ML. Total syntheses of (+)- and (-)-cacospongionolide B, cacospongionolide e, and related analogues. Preliminary study of structural features required for phospholipase a2 inhibition. The Journal of Organic Chemistry. 69: 5712-9. PMID 15307744 DOI: 10.1021/jo049285e  1
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