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Bruce D. Hammock - Publications

Affiliations: 
1975-1980 University of California, Riverside, Riverside, CA, United States 
 1980- Entomology University of California, Davis, Davis, CA 
Area:
Pesticide Biotechnology
Website:
http://www.biopestlab.ucdavis.edu/Our_People/Professor_Bruce_D_Hammock/
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452 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zhang CY, Duan JX, Yang HH, Sun CC, Zhong WJ, Tao JH, Guan XX, Jiang HL, Hammock BD, Hwang SH, Zhou Y, Guan CX. COX-2/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence. The Febs Journal. PMID 31646730 DOI: 10.1111/febs.15105  0.52
2019 Rand AA, Rajamani A, Kodani SD, Harris TR, Schlatt L, Barnych B, Passerini AG, Hammock BD. Epoxyeicosatrienoic acid (EET)-stimulated angiogenesis is mediated by epoxy hydroxyeicosatrienoic acids (EHETs) formed from COX-2. Journal of Lipid Research. PMID 31641036 DOI: 10.1194/jlr.M094219  0.36
2019 Dileepan M, Rastle-Simpson S, Greenberg Y, Wijesinghe DS, Kumar NG, Yang J, Hwang SH, Hammock BD, Sriramarao P, Rao SP. Effect Of Dual sEH/COX-2 Inhibition on Allergen-Induced Airway Inflammation. Frontiers in Pharmacology. 10: 1118. PMID 31611798 DOI: 10.3389/fphar.2019.01118  0.56
2019 Wang Y, Li Z, Barnych B, Huo J, Wan D, Vasylieva N, Xu J, Li P, Liu B, Zhang C, Hammock BD. Investigation of the Small Size of Nanobodies for a Sensitive Fluorescence Polarization Immunoassay for Small Molecules: 3-Phenoxybenzoic Acid, an Exposure Biomarker of Pyrethroid Insecticides as a Model. Journal of Agricultural and Food Chemistry. PMID 31589045 DOI: 10.1021/acs.jafc.9b04621  0.48
2019 Lee KSS, Yang J, Niu J, Ng CJ, Wagner KM, Dong H, Kodani SD, Wan D, Morisseau C, Hammock BD. Drug-Target Residence Time Affects Target Occupancy through Multiple Pathways. Acs Central Science. 5: 1614-1624. PMID 31572788 DOI: 10.1021/acscentsci.9b00770  0.72
2019 Yang J, Bruun DA, Wang C, Wan D, Reynolds CB, Phu K, Inceoglu B, Lein PJ, Hammock BD. Lipidomes of brain from rats acutely intoxicated with diisopropylfluorophosphate identifies potential therapeutic targets. Toxicology and Applied Pharmacology. 114749. PMID 31521729 DOI: 10.1016/j.taap.2019.114749  0.56
2019 Codony S, Valverde E, Leiva R, Brea J, Isabel Loza M, Morisseau C, Hammock BD, Vázquez S. Exploring the size of the lipophilic unit of the soluble epoxide hydrolase inhibitors. Bioorganic & Medicinal Chemistry. 115078. PMID 31488357 DOI: 10.1016/j.bmc.2019.115078  0.64
2019 Kramer JS, Woltersdorf S, Duflot T, Hiesinger K, Lillich FF, Knöll F, Wittmann SK, Klingler FM, Brunst S, Chaikuad A, Morisseau C, Hammock BD, Buccellati C, Sala A, Rovati GE, et al. Discovery of first in vivo active inhibitors of soluble epoxide hydrolase (sEH) phosphatase domain. Journal of Medicinal Chemistry. PMID 31436984 DOI: 10.1021/acs.jmedchem.9b00445  0.64
2019 Chen H, Ding Y, Yang Q, Barnych B, Gonzalez-Sapienza GG, Hammock BD, Wang M, Hua X. A Fluorescent "Turn Off-On" Small Molecule Monitoring Nano-Platform Based on Dendrimer-Like Peptides as Competitors. Acs Applied Materials & Interfaces. PMID 31433617 DOI: 10.1021/acsami.9b13111  0.36
2019 Liang Z, Zhang B, Xu M, Morisseau C, Hwang SH, Hammock BD, Li QX. TPPU, a Selective and Potent Dual Inhibitor of Soluble Epoxide Hydrolase and p38 Kinase Intervenes in Alzheimer's Signaling in Human Nerve Cells. Acs Chemical Neuroscience. PMID 31378059 DOI: 10.1021/acschemneuro.9b00271  0.8
2019 Wang Y, Xu J, Qiu YL, Li P, Liu B, Yang L, Barnych B, Zhang C, Hammock BD. A Highly Specific Monoclonal Antibody and Sensitive Quantum Dot Beads-based Fluorescence Immunochromatographic Test Strip for Tebuconazole Assay in Agricultural Products. Journal of Agricultural and Food Chemistry. PMID 31356079 DOI: 10.1021/acs.jafc.9b02832  0.48
2019 Shen Y, Peng W, Chen Q, Hammock BD, Liu J, Li D, Yang J, Ding J, Wang X. Anti-inflammatory treatment with a soluble epoxide hydrolase inhibitor attenuates seizures and epilepsy-associated depression in the LiCl-pilocarpine post-status epilepticus rat model. Brain, Behavior, and Immunity. PMID 31306773 DOI: 10.1016/j.bbi.2019.07.014  0.56
2019 Hiesinger K, Kramer JS, Achenbach J, Moser D, Weber J, Wittmann SK, Morisseau C, Angioni C, Geisslinger G, Kahnt AS, Kaiser A, Proschak A, Steinhilber D, Pogoryelov D, Wagner K, ... Hammock BD, et al. Computer-Aided Selective Optimization of Side Activities of Talinolol. Acs Medicinal Chemistry Letters. 10: 899-903. PMID 31223445 DOI: 10.1021/acsmedchemlett.9b00075  0.64
2019 Klocke J, Ulu A, Wu K, Rudolph B, Dragun D, Gollasch M, Schunck WH, Hammock BD, Riemekasten G, Enghard P. Prophylactic inhibition of soluble epoxide hydrolase delays onset of nephritis and ameliorates kidney damage in NZB/W F1 mice. Scientific Reports. 9: 8993. PMID 31222024 DOI: 10.1038/s41598-019-45299-5  0.44
2019 McReynolds CB, Hwang SH, Yang J, Wan D, Wagner K, Morisseau C, Li D, Schmidt WK, Hammock BD. Pharmaceutical Effects of Inhibiting the Soluble Epoxide Hydrolase in Canine Osteoarthritis. Frontiers in Pharmacology. 10: 533. PMID 31214021 DOI: 10.3389/fphar.2019.00533  0.72
2019 Panigrahy D, Gartung A, Yang J, Yang H, Gilligan MM, Sulciner ML, Bhasin SS, Bielenberg DR, Chang J, Schmidt BA, Piwowarski J, Fishbein A, Soler-Ferran D, Sparks MA, Staffa SJ, ... ... Hammock BD, et al. Preoperative stimulation of resolution and inflammation blockade eradicates micrometastases. The Journal of Clinical Investigation. 130. PMID 31205032 DOI: 10.1172/JCI127282  0.56
2019 Deol P, Yang J, Morisseau C, Hammock BD, Sladek FM. Dimethyl Sulfoxide Decreases Levels of Oxylipin Diols in Mouse Liver. Frontiers in Pharmacology. 10: 580. PMID 31191316 DOI: 10.3389/fphar.2019.00580  0.64
2019 Mukhtar H, Ma L, Pang Q, Zhou Y, Wang X, Xu T, Hammock BD, Wang J. Cyclic peptide: a safe and effective alternative to synthetic aflatoxin B-competitive antigens. Analytical and Bioanalytical Chemistry. PMID 31152222 DOI: 10.1007/s00216-019-01862-7  0.4
2019 Matsumoto N, Kataoka M, Hirosaki H, Morisseau C, Hammock BD, Suzuki E, Hasumi K. N-Substituted amino acid inhibitors of the phosphatase domain of the soluble epoxide hydrolase. Biochemical and Biophysical Research Communications. 515: 248-253. PMID 31146915 DOI: 10.1016/j.bbrc.2019.05.088  0.64
2019 Wan D, Yang J, McReynolds CB, Barnych B, Wagner KM, Morisseau C, Hwang SH, Sun J, Blöcher R, Hammock BD. and Metabolism of a Potent Inhibitor of Soluble Epoxide Hydrolase, 1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea. Frontiers in Pharmacology. 10: 464. PMID 31143115 DOI: 10.3389/fphar.2019.00464  0.72
2019 Tang Z, Liu X, Wang Y, Chen Q, Hammock BD, Xu Y. Nanobody-based fluorescence resonance energy transfer immunoassay for noncompetitive and simultaneous detection of ochratoxin a and ochratoxin B. Environmental Pollution (Barking, Essex : 1987). 251: 238-245. PMID 31082608 DOI: 10.1016/j.envpol.2019.04.135  0.48
2019 Huo J, Barnych B, Li Z, Wan D, Li D, Vasylieva N, Knezevic S, Osipitan OA, Scott J, Zhang J, Hammock BD. Hapten Synthesis, Antibody Development, and a Highly Sensitive Indirect Competitive Chemiluminescent Enzyme Immunoassay for Detection of Dicamba. Journal of Agricultural and Food Chemistry. PMID 31042038 DOI: 10.1021/acs.jafc.8b07134  0.4
2019 Mishra M, Tiwari S, Gunaseelan A, Li D, Hammock BD, Gomes AV. Improving the sensitivity of traditional western blotting via streptavidin containing poly horseradish peroxidase (PolyHRP). Electrophoresis. PMID 31021001 DOI: 10.1002/elps.201900059  0.4
2019 Liu ZB, Sun CP, Xu JX, Morisseau C, Hammock BD, Qiu F. Phytochemical constituents from Scutellaria baicalensis in soluble epoxide hydrolase inhibition: Kinetics and interaction mechanism merged with simulations. International Journal of Biological Macromolecules. PMID 30980876 DOI: 10.1016/j.ijbiomac.2019.04.055  0.64
2019 Ma M, Ren Q, Yang J, Zhang K, Xiong Z, Ishima T, Pu Y, Hwang SH, Toyoshima M, Iwayama Y, Hisano Y, Yoshikawa T, Hammock BD, Hashimoto K. Key role of soluble epoxide hydrolase in the neurodevelopmental disorders of offspring after maternal immune activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 30890645 DOI: 10.1073/pnas.1819234116  0.56
2019 Ren W, Li Z, Xu Y, Wan D, Barnych B, Li Y, Tu Z, He Q, Fu J, Hammock BD. One-step ultra-sensitive bioluminescent enzyme immunoassay based on nanobody/nano-luciferase fusion for detection of Aflatoxin B1 in cereal. Journal of Agricultural and Food Chemistry. PMID 30883117 DOI: 10.1021/acs.jafc.9b00688  0.4
2019 Hrdlička J, Neckář J, Papoušek F, Husková Z, Kikerlová S, Vaňourková Z, Vernerová Z, Akat F, Vašinová J, Hammock BD, Hwang SH, Imig JD, Falck JR, Červenka L, Kolář F. Epoxyeicosatrienoic Acid-Based Therapy Attenuates the Progression of Postischemic Heart Failure in Normotensive Sprague-Dawley but Not in Hypertensive Transgenic Rats. Frontiers in Pharmacology. 10: 159. PMID 30881303 DOI: 10.3389/fphar.2019.00159  0.52
2019 Zhu M, Wang L, Wu X, Na R, Wang Y, Li QX, Hammock BD. A novel and simple imidazo[1,2-a]pyridin fluorescent probe for the sensitive and selective imaging of cysteine in living cells and zebrafish. Analytica Chimica Acta. 1058: 155-165. PMID 30851849 DOI: 10.1016/j.aca.2019.01.023  0.8
2019 Liu Z, Wang K, Wu S, Wang Z, Ding G, Hao X, Li QX, Li J, Gee SJ, Hammock BD, Xu T. Development of a camelid variable domain of heavy chain antibody-based immunoassay for the detection of carbaryl in cereals. Journal of the Science of Food and Agriculture. PMID 30851058 DOI: 10.1002/jsfa.9672  0.8
2019 Vasylieva N, Kitamura S, Dong J, Barnych B, Hvorecny KL, Madden DR, Gee SJ, Wolan DW, Morisseau C, Hammock BD. Nanobody-based binding assay for the discovery of potent inhibitors of CFTR inhibitory factor (Cif). Analytica Chimica Acta. 1057: 106-113. PMID 30832908 DOI: 10.1016/j.aca.2018.12.060  0.8
2019 He J, Tao X, Wang K, Ding G, Li J, Li QX, Gee SJ, Hammock BD, Xu T. One-step immunoassay for the insecticide carbaryl using a chicken single-chain variable fragment (scFv) fused to alkaline phosphatase. Analytical Biochemistry. PMID 30831096 DOI: 10.1016/j.ab.2019.02.022  0.8
2019 Luo Y, Wu MY, Deng BQ, Huang J, Hwang SH, Li MY, Zhou CY, Zhang QY, Yu HB, Zhao DK, Zhang G, Qin L, Peng A, Hammock BD, Liu JY. Inhibition of soluble epoxide hydrolase attenuates a high-fat diet-mediated renal injury by activating PAX2 and AMPK. Proceedings of the National Academy of Sciences of the United States of America. PMID 30804206 DOI: 10.1073/pnas.1815746116  0.56
2019 Wang W, Yang J, Edin ML, Wang Y, Luo Y, Wan D, Yang H, Song CQ, Xue W, Sanidad KZ, Song M, Bisbee HA, Bradbury JA, Nan G, Zhang J, ... ... Hammock BD, et al. Targeted metabolomics identifies the cytochrome P450 monooxygenase eicosanoid pathway as a novel therapeutic target of colon tumorigenesis. Cancer Research. PMID 30803995 DOI: 10.1158/0008-5472.CAN-18-3221  0.56
2019 Yao L, Cao B, Cheng Q, Cai W, Ye C, Liang J, Liu W, Tan L, Yan M, Li B, He J, Hwang SH, Zhang X, Wang C, Ai D, ... Hammock BD, et al. Inhibition of Soluble Epoxide Hydrolase Ameliorates Hyperhomocysteinemia-Induced Hepatic Steatosis by Enhancing β-oxidation of Fatty Acid in Mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 30789748 DOI: 10.1152/ajpgi.00148.2018  0.52
2019 de Oliveira GS, Adriani PP, Ribeiro JA, Morisseau C, Hammock BD, Dias MVB, Chambergo FS. The molecular structure of an epoxide hydrolase from Trichoderma reesei in complex with urea or amide-based inhibitors. International Journal of Biological Macromolecules. PMID 30771398 DOI: 10.1016/j.ijbiomac.2019.02.070  0.64
2019 Wang K, Liu Z, Ding G, Li J, Vasylieva N, Li QX, Li D, Gee SJ, Hammock BD, Xu T. Development of a one-step immunoassay for triazophos using camel single-domain antibody-alkaline phosphatase fusion protein. Analytical and Bioanalytical Chemistry. PMID 30706076 DOI: 10.1007/s00216-018-01563-7  0.8
2019 Gartung A, Yang J, Sukhatme VP, Bielenberg DR, Fernandes D, Chang J, Schmidt BA, Hwang SH, Zurakowski D, Huang S, Kieran MW, Hammock BD, Panigrahy D. Suppression of chemotherapy-induced cytokine/lipid mediator surge and ovarian cancer by a dual COX-2/sEH inhibitor. Proceedings of the National Academy of Sciences of the United States of America. PMID 30647111 DOI: 10.1073/pnas.1803999116  0.56
2018 Hiesinger K, Wagner KM, Hammock BD, Proschak E, Hwang SH. Development of Multitarget Agents Possessing Soluble Epoxide Hydrolase Inhibitory Activity. Prostaglandins & Other Lipid Mediators. PMID 30593866 DOI: 10.1016/j.prostaglandins.2018.12.003  0.72
2018 Wang K, Vasylieva N, Wan D, Eads DA, Yang J, Tretten T, Barnych B, Li J, Li QX, Gee SJ, Hammock BD, Xu T. Quantitative Detection of Fipronil and Fipronil-Sulfone in Sera of Black-Tailed Prairie Dogs and Rats after Oral Exposure to Fipronil by Camel Single-Domain Antibody-Based Immunoassays. Analytical Chemistry. PMID 30521755 DOI: 10.1021/acs.analchem.8b04653  0.8
2018 Chen H, Yang Q, Ding Y, Vasylieva N, Bever CS, Hua X, Wang M, Hammock BD. Competitive and noncompetitive immunoassays for the detection of benzothiostrobin using magnetic nanoparticles and fluorescein isothiocyanate-labeled peptides. Analytical and Bioanalytical Chemistry. PMID 30478514 DOI: 10.1007/s00216-018-1478-8  0.4
2018 Lakkappa N, Krishnamurthy PT, Pandareesh MD, Hammock BD, Hwang SH. Soluble epoxide hydrolase inhibitor, APAU, protects dopaminergic neurons against rotenone induced neurotoxicity: Implications for Parkinson's disease. Neurotoxicology. PMID 30472438 DOI: 10.1016/j.neuro.2018.11.010  0.52
2018 Hennebelle M, Metherel AH, Kitson AP, Otoki Y, Yang J, Lee KSS, Hammock BD, Bazinet RP, Taha AY. Brain oxylipin concentrations following hypercapnia / ischemia: effects of brain dissection and dissection time. Journal of Lipid Research. PMID 30463986 DOI: 10.1194/jlr.D084228  0.56
2018 de Oliveira GS, Adriani PP, Wu H, Morisseau C, Hammock BD, Chambergo FS. Substrate and inhibitor selectivity, and biological activity of an epoxide hydrolase from Trichoderma reesei. Molecular Biology Reports. PMID 30426381 DOI: 10.1007/s11033-018-4481-4  0.64
2018 Kodani SD, Wan D, Wagner KM, Hwang SH, Morisseau C, Hammock BD. Design and Potency of Dual Soluble Epoxide Hydrolase/Fatty Acid Amide Hydrolase Inhibitors. Acs Omega. 3: 14076-14086. PMID 30411058 DOI: 10.1021/acsomega.8b01625  0.72
2018 Huo J, Li Z, Wan D, Li D, Qi M, Barnych B, Vasylieva N, Zhang J, Hammock BD. Development of a Highly Sensitive Direct Competitive Fluorescence Enzyme Immunoassay Based on a Nanobody-Alkaline Phosphatase Fusion Protein for Detection of 3-Phenoxybenzoic Acid in Urine. Journal of Agricultural and Food Chemistry. PMID 30293433 DOI: 10.1021/acs.jafc.8b04521  0.4
2018 He J, Tian J, Xu J, Wang K, Li J, Gee SJ, Hammock BD, Li QX, Xu T. Strong and oriented conjugation of nanobodies onto magnetosomes for the development of a rapid immunomagnetic assay for the environmental detection of tetrabromobisphenol-A. Analytical and Bioanalytical Chemistry. PMID 30066195 DOI: 10.1007/s00216-018-1270-9  0.8
2018 Harris TR, Kodani S, Rand AA, Yang J, Imai DM, Hwang SH, Hammock BD. Celecoxib does not protect against fibrosis and inflammation in a carbon tetrachloride-induced model of liver injury. Molecular Pharmacology. PMID 29844231 DOI: 10.1124/mol.118.111831  0.56
2018 Burmistrov V, Morisseau C, Pitushkin D, Karlov D, Fayzullin RR, Butov GM, Hammock BD. Adamantyl thioureas as soluble epoxide hydrolase inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 29803731 DOI: 10.1016/j.bmcl.2018.05.024  0.64
2018 Ren Q, Ma M, Yang J, Nonaka R, Yamaguchi A, Ishikawa KI, Kobayashi K, Murayama S, Hwang SH, Saiki S, Akamatsu W, Hattori N, Hammock BD, Hashimoto K. Soluble epoxide hydrolase plays a key role in the pathogenesis of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 29735655 DOI: 10.1073/pnas.1802179115  0.56
2018 Lee KSS, Liu JY, Wagner KM, Pakhomova S, Dong H, Morisseau C, Fu SH, Yang J, Wang P, Ulu A, Mate CA, Nguyen LV, Hwang SH, Edin ML, Mara AA, ... ... Hammock BD, et al. Correction to Optimized Inhibitors of Soluble Epoxide Hydrolase Improve in Vitro Target Residence Time and in Vivo Efficacy. Journal of Medicinal Chemistry. PMID 29701466 DOI: 10.1021/acs.jmedchem.8b00582  0.72
2018 Martinez JA, Yang J, Wertheim BC, Roe DJ, Schriewer A, Lance P, Alberts DS, Hammock BD, Thompson PA. Celecoxib use and circulating oxylipins in a colon polyp prevention trial. Plos One. 13: e0196398. PMID 29698447 DOI: 10.1371/journal.pone.0196398  0.56
2018 Lassabe G, Kramer K, Hammock BD, Gonzalez-Sapienza GG, González-Techera A. Noncompetitive Homogeneous detection of small molecules using synthetic nanopeptamer based Luminescent Oxygen Channeling. Analytical Chemistry. PMID 29694028 DOI: 10.1021/acs.analchem.8b00657  0.36
2018 Bever CS, Rand AA, Nording M, Taft D, Kalanetra KM, Mills DA, Breck MA, Smilowitz JT, German JB, Hammock BD. Effects of triclosan in breast milk on the infant fecal microbiome. Chemosphere. 203: 467-473. PMID 29635158 DOI: 10.1016/j.chemosphere.2018.03.186  0.36
2018 Cui X, Vasylieva N, Shen D, Barnych B, Yang J, He Q, Jiang Z, Zhao S, Hammock BD. Biotinylated single-chain variable fragment-based enzyme-linked immunosorbent assay for glycocholic acid. The Analyst. PMID 29629470 DOI: 10.1039/c7an02024d  0.56
2018 Blöcher R, Wagner KM, Gopireddy RR, Harris TR, Wu H, Barnych B, Hwang SH, Xiang YK, Proschak E, Morisseau C, Hammock BD. Orally available soluble epoxide hydrolase/phosphodiesterase 4 dual inhibitor treats inflammatory pain. Journal of Medicinal Chemistry. PMID 29614224 DOI: 10.1021/acs.jmedchem.7b01804  0.72
2018 Červenka L, Husková Z, Kopkan L, Kikerlová S, Sedláková L, Vaňourková Z, Alánová P, Kolář F, Hammock BD, Hwang SH, Imig JD, Falck JR, Sadowski J, Kompanowska-Jezierska E, Neckář J. Two pharmacological epoxyeicosatrienoic acid-enhancing therapies are effectively antihypertensive and reduce the severity of ischemic arrhythmias in rats with angiotensin II-dependent hypertension. Journal of Hypertension. PMID 29570510 DOI: 10.1097/HJH.0000000000001708  0.52
2018 Hao L, Kearns J, Scott S, Wu D, Kodani SD, Morisseau C, Hammock BD, Sun X, Wang S, Zhao L. Indomethacin enhanced brown fat activity. The Journal of Pharmacology and Experimental Therapeutics. PMID 29567865 DOI: 10.1124/jpet.117.246256  0.64
2018 Pecic S, Zeki AA, Xu X, Jin GY, Zhang S, Kodani S, Halim M, Morisseau C, Hammock BD, Deng SX. Novel piperidine-derived amide sEH inhibitors as mediators of lipid metabolism with improved stability. Prostaglandins & Other Lipid Mediators. PMID 29567338 DOI: 10.1016/j.prostaglandins.2018.02.004  0.64
2018 Čertíková Chábová V, Kujal P, Škaroupková P, Varňourková Z, Vacková Š, Husková Z, Kikerlová S, Sadowski J, Kompanowska-Jezierska E, Baranowska I, Hwang SH, Hammock BD, Imig JD, Tesař V, Červenka L. Combined Inhibition of Soluble Epoxide Hydrolase and Renin-Angiotensin System Exhibits Superior Renoprotection to Renin-Angiotensin System Blockade in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats with Established Chronic Kidney Disease. Kidney & Blood Pressure Research. 43: 329-349. PMID 29529602 DOI: 10.1159/000487902  0.52
2018 Cam M, Durieu E, Bodin M, Manousopoulou A, Koslowski S, Vasylieva N, Barnych B, Hammock BD, Bohl B, Koch P, Omori C, Yamamoto K, Hata S, Suzuki T, Karg F, et al. Induction of Amyloid-β42 Production by Fipronil and Other Pyrazole Insecticides. Journal of Alzheimer's Disease : Jad. PMID 29504531 DOI: 10.3233/JAD-170875  0.4
2018 Yamanashi H, Boeglin WE, Morisseau C, Davis RW, Sulikowski GA, Hammock BD, Brash AR. Catalytic activities of mammalian epoxide hydrolases withandfatty acid epoxides relevant to skin barrier function. Journal of Lipid Research. PMID 29459481 DOI: 10.1194/jlr.M082701  0.64
2018 Kodani SD, Bhakta S, Hwang SH, Pakhomova S, Newcomer ME, Morisseau C, Hammock BD. Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase. Bioorganic & Medicinal Chemistry Letters. PMID 29366648 DOI: 10.1016/j.bmcl.2018.01.003  0.64
2018 Rand AA, Helmer PO, Inceoglu B, Hammock BD, Morisseau C. LC-MS/MS Analysis of the Epoxides and Diols Derived from the Endocannabinoid Arachidonoyl Ethanolamide. Methods in Molecular Biology (Clifton, N.J.). 1730: 123-133. PMID 29363071 DOI: 10.1007/978-1-4939-7592-1_10  0.64
2018 Bastan I, Ge XN, Dileepan M, Greenberg YG, Guedes AG, Hwang SH, Hammock BD, Washabau RJ, Rao SP, Sriramarao P. Inhibition of soluble epoxide hydrolase attenuates eosinophil recruitment and food allergen-induced gastrointestinal inflammation. Journal of Leukocyte Biology. PMID 29345370 DOI: 10.1002/JLB.3MA1017-423R  0.52
2018 Qiu YL, Li P, Dong S, Zhang X, Yang Q, Wang Y, Ge J, Hammock BD, Zhang C, Liu X. Phage-mediated competitive chemiluminescent immunoassay for detecting Cry1Ab toxin by using an anti-idiotypic camel nanobody. Journal of Agricultural and Food Chemistry. PMID 29293334 DOI: 10.1021/acs.jafc.7b04923  0.48
2017 Burmistrov V, Morisseau C, Harris TR, Butov G, Hammock BD. Effects of adamantane alterations on soluble epoxide hydrolase inhibition potency, physical properties and metabolic stability. Bioorganic Chemistry. 76: 510-527. PMID 29310082 DOI: 10.1016/j.bioorg.2017.12.024  0.64
2017 Wang F, Zhang H, Ma AH, Yu W, Zimmermann M, Yang J, Hwang SH, Zhu D, Lin TY, Malfatti M, Turteltaub KW, Henderson PT, Airhart S, Hammock BD, Yuan J, et al. COX-2/sEH Dual Inhibitor PTUPB Potentiates the Anti-tumor Efficacy of Cisplatin. Molecular Cancer Therapeutics. PMID 29284644 DOI: 10.1158/1535-7163.MCT-16-0818  0.56
2017 Hu J, Dziumbla S, Lin J, Bibli SI, Zukunft S, de Mos J, Awwad K, Frömel T, Jungmann A, Devraj K, Cheng Z, Wang L, Fauser S, Eberhart CG, Sodhi A, ... Hammock BD, et al. Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy. Nature. 552: 248-252. PMID 29211719 DOI: 10.1038/nature25013  0.48
2017 Lakkappa N, Krishnamurthy PT, Yamjala K, Hwang SH, Hammock BD, Babu B. Evaluation of antiparkinson activity of PTUPB by measuring dopamine and its metabolites in Drosophila melanogaster: LC-MS/MS method development. Journal of Pharmaceutical and Biomedical Analysis. 149: 457-464. PMID 29169114 DOI: 10.1016/j.jpba.2017.11.043  0.52
2017 Li J, Zhou Y, Wang H, Gao Y, Li L, Hwang SH, Ji X, Hammock BD. COX-2/sEH dual inhibitor PTUPB suppresses glioblastoma growth by targeting epidermal growth factor receptor and hyaluronan mediated motility receptor. Oncotarget. 8: 87353-87363. PMID 29152086 DOI: 10.18632/oncotarget.20928  0.52
2017 Deng BQ, Luo Y, Kang X, Li CB, Morisseau C, Yang J, Lee KSS, Huang J, Hu DY, Wu MY, Peng A, Hammock BD, Liu JY. Epoxide metabolites of arachidonate and docosahexaenoate function conversely in acute kidney injury involved in GSK3β signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 29109264 DOI: 10.1073/pnas.1705615114  0.64
2017 Deol P, Fahrmann J, Yang J, Evans JR, Rizo A, Grapov D, Salemi M, Wanichthanarak K, Fiehn O, Phinney B, Hammock BD, Sladek FM. Omega-6 and omega-3 oxylipins are implicated in soybean oil-induced obesity in mice. Scientific Reports. 7: 12488. PMID 28970503 DOI: 10.1038/s41598-017-12624-9  0.56
2017 Cui X, Vasylieva N, Wu P, Barnych B, Yang J, Shen D, He Q, Gee SJ, Zhao S, Hammock BD. Development of an Indirect Competitive ELISA for Glycocholic Acid Based on Chicken Single-Chain Variable Fragment (scFv) Antibodies. Analytical Chemistry. PMID 28942640 DOI: 10.1021/acs.analchem.7b03190  0.8
2017 Yang J, Oh YT, Wan D, Watanabe RM, Hammock BD, Youn JH. Postprandial effect to decrease soluble epoxide hydrolase activity: roles of insulin and gut microbiota. The Journal of Nutritional Biochemistry. 49: 8-14. PMID 28863368 DOI: 10.1016/j.jnutbio.2017.07.006  0.56
2017 Inceoglu B, Bettaieb A, Haj FG, Gomes AV, Hammock BD. Modulation of mitochondrial dysfunction and endoplasmic reticulum stress are key mechanisms for the wide-ranging actions of epoxy fatty acids and soluble epoxide hydrolase inhibitors. Prostaglandins & Other Lipid Mediators. PMID 28847566 DOI: 10.1016/j.prostaglandins.2017.08.003  0.4
2017 Hasegawa E, Inafuku S, Mulki L, Okunuki Y, Yanai R, Smith KE, Kim CB, Klokman G, Bielenberg DR, Puli N, Falck JR, Husain D, Miller JW, Edin ML, Zeldin DC, ... ... Hammock BD, et al. Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization. Proceedings of the National Academy of Sciences of the United States of America. PMID 28827330 DOI: 10.1073/pnas.1620898114  0.32
2017 Bettaieb A, Koike S, Hsu MF, Ito Y, Chahed S, Bachaalany S, Gruzdev A, Calvo-Rubio M, Lee KSS, Inceoglu B, Imig JD, Villalba JM, Zeldin DC, Hammock BD, Haj FG. Soluble epoxide hydrolase in podocytes is a significant contributor to renal function under hyperglycemia. Biochimica Et Biophysica Acta. PMID 28757338 DOI: 10.1016/j.bbagen.2017.07.021  0.4
2017 Hennebelle M, Zhang Z, Metherel AH, Kitson AP, Otoki Y, Richardson CE, Yang J, Lee KSS, Hammock BD, Zhang L, Bazinet RP, Taha AY. Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission. Scientific Reports. 7: 4342. PMID 28659576 DOI: 10.1038/s41598-017-02914-7  0.56
2017 Huang F, Liu Y, Yang X, Che D, Qiu K, Hammock BD, Wang J, Wang MH, Chen J, Huang H. Shexiang Baoxin pills promotes angiogenesis in myocardial infarction rats via up-regulation of 20-HETE-mediated endothelial progenitor cells mobilization. Atherosclerosis. 263: 184-191. PMID 28646793 DOI: 10.1016/j.atherosclerosis.2017.06.012  0.4
2017 Wagner KM, McReynolds CB, Schmidt WK, Hammock BD. Soluble epoxide hydrolase as a therapeutic target for pain, inflammatory and neurodegenerative diseases. Pharmacology & Therapeutics. PMID 28642117 DOI: 10.1016/j.pharmthera.2017.06.006  0.72
2017 Yefidoff-Freedman R, Fan J, Yan L, Zhang Q, Dos Santos GRRM, Rana S, Contreras JI, Sahoo R, Wan D, Yang J, Dias-Teixeira KL, Morisseau C, Du R, Halperin JA, Hammock BD, et al. Development of 1-((1,4-trans)-4-aryloxycyclohexyl)-3-arylurea Activators of the Heme Regulated Inhibitor as Selective Activators of Eucaryotic Translation Initiation Factor 2 Alpha (eIF2α) Phosphorylation Arm of the Integrated Endoplasmic Reticulum Stress Response. Journal of Medicinal Chemistry. PMID 28590739 DOI: 10.1021/acs.jmedchem.7b00059  0.64
2017 Fischer GJ, Bacon W, Yang J, Palmer JM, Dagenais T, Hammock BD, Keller NP. Lipoxygenase Activity Accelerates Programmed Spore Germination in Aspergillus fumigatus. Frontiers in Microbiology. 8: 831. PMID 28536571 DOI: 10.3389/fmicb.2017.00831  0.56
2017 Goswami SK, Rand AA, Wan D, Yang J, Inceoglu B, Thomas M, Morisseau C, Yang GY, Hammock BD. Pharmacological inhibition of soluble epoxide hydrolase or genetic deletion reduces diclofenac-induced gastric ulcers. Life Sciences. PMID 28522175 DOI: 10.1016/j.lfs.2017.05.018  0.64
2017 Bettaieb A, Koike S, Chahed S, Zhao Y, Bachaalany S, Hashoush N, Graham J, Huma F, Havel PJ, Gruzdev A, Zeldin DC, Hammock BD, Haj FG. Podocyte-specific soluble epoxide hydrolase deficiency in mice attenuates acute kidney injury. The Febs Journal. PMID 28485854 DOI: 10.1111/febs.14100  0.32
2017 Orcholski ME, Khurshudyan A, Shamskhou EA, Yuan K, Chen IY, Kodani SD, Morisseau C, Hammock BD, Hong EM, Alexandrova L, Alastalo TP, Berry G, Zamanian RT, de Jesus Perez VA. REDUCED CARBOXYLESTERASE 1 IS ASSOCIATED WITH ENDOTHELIAL INJURY IN METHAMPHETAMINE INDUCED PULMONARY ARTERIAL HYPERTENSION. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00453.2016. PMID 28473326 DOI: 10.1152/ajplung.00453.2016  0.64
2017 Kitamura S, Morisseau C, Harris TR, Inceoglu B, Hammock BD. Occurrence of urea-based soluble epoxide hydrolase inhibitors from the plants in the order Brassicales. Plos One. 12: e0176571. PMID 28472063 DOI: 10.1371/journal.pone.0176571  0.64
2017 Barnych B, Rand AA, Cajka T, Lee KSS, Hammock BD. Synthesis of cyclooxygenase metabolites of 8,9-epoxyeicosatrienoic acid (EET): 11- and 15-hydroxy 8,9-EETs. Organic & Biomolecular Chemistry. PMID 28470279 DOI: 10.1039/c7ob00789b  0.36
2017 Li D, Cui Y, Morisseau C, Gee SJ, Bever CRS, Liu X, Wu J, Hammock BD, Ying YB. Nanobody based Immunoassay for Human Soluble Epoxide Hydrolase Detection using PolyHRP for Signal Enhancement-the Rediscovery of PolyHRP? Analytical Chemistry. PMID 28460522 DOI: 10.1021/acs.analchem.7b01247  0.8
2017 Kandhi S, Zhang B, Froogh G, Qin J, Alruwali N, Le Y, Yang YM, Hwang SH, Hammock BD, Wolin MS, Huang A, Sun D. EETs promote hypoxic pulmonary vasoconstriction via constrictor prostanoids. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00038.2017. PMID 28450284 DOI: 10.1152/ajplung.00038.2017  0.52
2017 Wang Z, Fang Y, Teague J, Wong H, Morisseau C, Hammock BD, Rock DA, Wang Z. In Vitro Metabolism of Oprozomib, an Oral Proteasome Inhibitor: Role of Epoxide Hydrolases and Cytochrome P450s. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 28428366 DOI: 10.1124/dmd.117.075226  0.64
2017 Barnych B, Vasylieva N, Joseph T, Hulsizer S, Nguyen H, Cajka T, Pessah I, Wulff H, Gee S, Hammock B. Development of tetramethylenedisulfotetramine (TETS) hapten library: synthesis, electrophysiological studies and immune response in rabbits. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28411375 DOI: 10.1002/chem.201700783  0.4
2017 Chu S, Baker MR, Leong G, Letcher RJ, Gee SJ, Hammock BD, Li QX. Exploring adduct formation between human serum albumin and eleven organophosphate ester flame retardants and plasticizers using MALDI-TOF/TOF and LC-Q/TOF. Chemosphere. 180: 169-177. PMID 28407546 DOI: 10.1016/j.chemosphere.2017.03.124  0.8
2017 Vasylieva N, Barnych B, Rand AA, Inceoglu B, Gee SJ, Hammock BD. Sensitive immunoassay for detection and quantification of the neurotoxin, tetramethylenedisulfotetramine (TETS). Analytical Chemistry. PMID 28398746 DOI: 10.1021/acs.analchem.7b00846  0.8
2017 Rand AA, Barnych B, Morisseau C, Cajka T, Lee KS, Panigrahy D, Hammock BD. Cyclooxygenase-derived proangiogenic metabolites of epoxyeicosatrienoic acids. Proceedings of the National Academy of Sciences of the United States of America. PMID 28396419 DOI: 10.1073/pnas.1616893114  0.64
2017 Hvorecny KL, Bahl CD, Kitamura S, Lee KS, Hammock BD, Morisseau C, Madden DR. Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase. Structure (London, England : 1993). PMID 28392259 DOI: 10.1016/j.str.2017.03.002  0.64
2017 Trindade da Silva CA, Bettaieb A, Napimoga MH, Lee KS, Inceoglu B, Ueira-Vieira C, Bruun D, Goswami SK, Haj FG, Hammock BD. Soluble epoxide hydrolase pharmacological inhibition decreases alveolar bone loss by modulating host inflammatory response, RANK-related signaling, ER stress and apoptosis. The Journal of Pharmacology and Experimental Therapeutics. PMID 28356494 DOI: 10.1124/jpet.116.238113  0.4
2017 Vasylieva N, Barnych B, Wan D, El-Sheikh EA, Nguyen HM, Wulff H, McMahen R, Strynar M, Gee SJ, Hammock BD. Hydroxy-fipronil is a new urinary biomarker of exposure to fipronil. Environment International. PMID 28343720 DOI: 10.1016/j.envint.2017.03.012  0.8
2017 Islam O, Patil P, Goswami SK, Razdan R, Inamdar MN, Rizwan M, Mathew J, Inceoglu B, Lee KS, Hwang SH, Hammock BD. Inhibitors of soluble epoxide hydrolase minimize ischemia-reperfusion induced cardiac damage in normal, hypertensive and diabetic rats. Cardiovascular Therapeutics. PMID 28296232 DOI: 10.1111/1755-5922.12259  0.52
2017 Wagner K, Gilda J, Yang J, Wan D, Morisseau C, Gomes AV, Hammock BD. Soluble epoxide hydrolase inhibition alleviates neuropathy in Akita (Ins2 Akita) mice. Behavioural Brain Research. PMID 28259677 DOI: 10.1016/j.bbr.2017.02.048  0.64
2017 Hennebelle M, Otoki Y, Yang J, Hammock BD, Levitt AJ, Taha AY, Swardfager W. Altered soluble epoxide hydrolase-derived oxylipins in patients with seasonal major depression: An exploratory study. Psychiatry Research. 252: 94-101. PMID 28259037 DOI: 10.1016/j.psychres.2017.02.056  0.56
2017 Hu P, Wu X, Khandelwal AR, Yu W, Xu Z, Chen L, Yang J, Weisbrod RM, Lee KS, Seta F, Hammock BD, Cohen RA, Zeng C, Tong X. Endothelial Nox4-based NADPH oxidase regulates atherosclerosis via soluble epoxide hydrolase. Biochimica Et Biophysica Acta. PMID 28185955 DOI: 10.1016/j.bbadis.2017.02.004  0.56
2017 Richardson CE, Hennebelle M, Otoki Y, Zamora D, Yang J, Hammock BD, Taha AY. Lipidomic quantitation of oxidized fatty acids in plant and algae oils. Journal of Agricultural and Food Chemistry. PMID 28157307 DOI: 10.1021/acs.jafc.6b05559  0.56
2017 Wan D, Yang J, Barnych B, Hwang SH, Lee KS, Cui Y, Niu J, Watsky MA, Hammock BD. A new sensitive LC/MS/MS analysis of vitamin D metabolites using a click derivatization reagent, 2-nitrosopyridine. Journal of Lipid Research. PMID 28148721 DOI: 10.1194/jlr.D073536  0.56
2017 Liu X, Tang Z, Duan Z, He Z, Shu M, Wang X, Gee SJ, Hammock BD, Xu Y. Nanobody-based enzyme immunoassay for ochratoxin A in cereal with high resistance to matrix interference. Talanta. 164: 154-158. PMID 28107910 DOI: 10.1016/j.talanta.2016.11.039  0.8
2017 Lee KS, Henriksen NM, Ng CJ, Yang J, Jia W, Morisseau C, Andaya A, Gilson MK, Hammock BD. Probing the orientation of inhibitor and epoxy-eicosatrienoic acid binding in the active site of soluble epoxide hydrolase. Archives of Biochemistry and Biophysics. 613: 1-11. PMID 27983948 DOI: 10.1016/j.abb.2016.10.017  0.64
2016 Kamita SG, Mulligan S, Cornel AJ, Hammock BD. Quantification of GST and esterase activities in pyrethrin-resistant mosquitoes using pyrethroid-like fluorescent substrates. International Journal of Pest Management. 62: 276-283. PMID 28736488 DOI: 10.1080/09670874.2016.1175685  0.84
2016 Supp DM, Hahn JM, McFarland KL, Combs KA, Lee KS, Inceoglu B, Wan D, Boyce ST, Hammock BD. Soluble Epoxide Hydrolase Inhibition and Epoxyeicosatrienoic Acid Treatment Improve Vascularization of Engineered Skin Substitutes. Plastic and Reconstructive Surgery. Global Open. 4: e1151. PMID 28293507 DOI: 10.1097/GOX.0000000000001151  0.4
2016 Ulu A, Inceoglu B, Yang J, Singh V, Vito S, Wulff H, Hammock BD. Inhibition of soluble epoxide hydrolase as a novel approach to high dose diazepam induced hypotension. Journal of Clinical Toxicology. 6. PMID 28255523 DOI: 10.4172/2161-0495.1000300  0.56
2016 McLellan GJ, Aktas Z, Hennes-Beean E, Kolb AW, Larsen IV, Schmitz EJ, Clausius HR, Yang J, Hwang SH, Morisseau C, Inceoglu B, Hammock BD, Brandt CR. Effect of a Soluble Epoxide Hydrolase Inhibitor, UC1728, on LPS-Induced Uveitis in the Rabbit. Journal of Ocular Biology. 4. PMID 28066796  0.64
2016 Hwang SH, Wagner K, Xu J, Yang J, Li X, Cao Z, Morisseau C, Lee KS, Hammock BD. Chemical synthesis and biological evaluation of ω-hydroxy polyunsaturated fatty acids. Bioorganic & Medicinal Chemistry Letters. PMID 28025003 DOI: 10.1016/j.bmcl.2016.12.002  0.64
2016 Zhang Y, Hong G, Lee KS, Hammock BD, Gebremedhin D, Harder DR, Koehler RC, Sapirstein A. Inhibition of soluble epoxide hydrolase augments astrocyte release of vascular endothelial growth factor and neuronal recovery after oxygen-glucose deprivation. Journal of Neurochemistry. PMID 28002622 DOI: 10.1111/jnc.13933  0.4
2016 Flitter BA, Hvorecny KL, Ono E, Eddens T, Yang J, Kwak DH, Bahl CD, Hampton TH, Morisseau C, Hammock BD, Liu X, Lee JS, Kolls JK, Levy BD, Madden DR, et al. Pseudomonas aeruginosa sabotages the generation of host proresolving lipid mediators. Proceedings of the National Academy of Sciences of the United States of America. PMID 27980032 DOI: 10.1073/pnas.1610242114  0.64
2016 Wang W, Yang J, Yang H, Sanidad KZ, Hammock BD, Kim D, Zhang G. Effects of high-fat diet on plasma profiles of eicosanoid metabolites in mice. Prostaglandins & Other Lipid Mediators. PMID 27913146 DOI: 10.1016/j.prostaglandins.2016.11.003  0.56
2016 Wang W, Yang J, Qi W, Yang H, Wang C, Tan B, Hammock BD, Park Y, Kim D, Zhang G. Lipidomic profiling of high-fat diet-induced obesity in mice: Importance of cytochrome P450-derived fatty acid epoxides. Obesity (Silver Spring, Md.). PMID 27891824 DOI: 10.1002/oby.21692  0.56
2016 Harris TR, Kodani S, Yang J, Imai DM, Hammock BD. An ω-3-enriched diet alone does not attenuate CCl4-induced hepatic fibrosis. The Journal of Nutritional Biochemistry. 38: 93-101. PMID 27732914 DOI: 10.1016/j.jnutbio.2016.08.010  1
2016 Wagner SD, Kurobe T, Hammock BG, Lam CH, Wu G, Vasylieva N, Gee SJ, Hammock BD, Teh SJ. Developmental effects of fipronil on Japanese Medaka (Oryzias latipes) embryos. Chemosphere. 166: 511-520. PMID 27710886 DOI: 10.1016/j.chemosphere.2016.09.069  0.8
2016 Liu JY, Morisseau C, Huang H, Hammock BD. Screening of Soluble Epoxide Hydrolase Inhibitory Ingredients from Traditional Chinese Medicines for Anti-inflammatory Use. Journal of Ethnopharmacology. PMID 27702689 DOI: 10.1016/j.jep.2016.09.044  1
2016 Kodani SD, Overby HB, Morisseau C, Chen J, Zhao L, Hammock BD. Parabens inhibit fatty acid amide hydrolase: A potential role in paraben-enhanced 3T3-L1 adipocyte differentiation. Toxicology Letters. PMID 27659731 DOI: 10.1016/j.toxlet.2016.09.011  0.64
2016 Li D, Liu Y, Zhang X, Lv H, Pang W, Sun X, Gan LM, Hammock BD, Ai D, Zhu Y. Inhibition of soluble epoxide hydrolase alleviated atherosclerosis by reducing monocyte infiltration in Ldlr(-/-) mice. Journal of Molecular and Cellular Cardiology. PMID 27496380 DOI: 10.1016/j.yjmcc.2016.08.001  1
2016 Pessah IN, Rogawski MA, Tancredi DJ, Wulff H, Zolkowska D, Bruun DA, Hammock BD, Lein PJ. Models to identify treatments for the acute and persistent effects of seizure-inducing chemical threat agents. Annals of the New York Academy of Sciences. PMID 27467073 DOI: 10.1111/nyas.13137  1
2016 Khan MA, Hwang SH, Sharma A, Corbett JA, Hammock BD, Imig JD. A dual COX-2/sEH inhibitor improves the metabolic profile and reduces kidney injury in Zucker diabetic fatty rat. Prostaglandins & Other Lipid Mediators. PMID 27432695 DOI: 10.1016/j.prostaglandins.2016.07.003  0.52
2016 Gong Y, Fu Z, Edin ML, Liu CH, Wang Z, Shao Z, Fredrick TW, Saba NJ, Morss PC, Burnim SB, Meng SS, Lih FB, Stephen Lee KS, Moran EP, SanGiovanni JP, ... ... Hammock BD, et al. Cytochrome P450 Oxidase 2C Inhibition Adds to ω-3 Long-Chain Polyunsaturated Fatty Acids Protection Against Retinal and Choroidal Neovascularization. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 27417579 DOI: 10.1161/ATVBAHA.116.307558  1
2016 Xu J, Morisseau C, Yang J, Lee KS, Kamita SG, Hammock BD. Ingestion of the epoxide hydrolase inhibitor AUDA modulates immune responses of the mosquito, Culex quinquefasciatus during blood feeding. Insect Biochemistry and Molecular Biology. PMID 27369469 DOI: 10.1016/j.ibmb.2016.06.011  0.84
2016 Mouchlis VD, Morisseau C, Hammock BD, Li S, McCammon JA, Dennis EA. Computer-aided drug design guided by hydrogen/deuterium exchange mass spectrometry: A powerful combination for the development of potent and selective inhibitors of Group VIA calcium-independent phospholipase A2. Bioorganic & Medicinal Chemistry. 24: 4801-4811. PMID 27320659 DOI: 10.1016/j.bmc.2016.05.009  0.64
2016 Taha AY, Hennebelle M, Yang J, Zamora D, Rapoport SI, Hammock BD, Ramsden CE. Regulation of rat plasma and cerebral cortex oxylipin concentrations with increasing levels of dietary linoleic acid. Prostaglandins, Leukotrienes, and Essential Fatty Acids. PMID 27282298 DOI: 10.1016/j.plefa.2016.05.004  0.56
2016 Sharma A, Khan MA, Levick SP, Lee KS, Hammock BD, Imig JD. Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis. International Journal of Molecular Sciences. 17. PMID 27213332 DOI: 10.3390/ijms17050751  0.4
2016 Bever CS, Dong JX, Vasylieva N, Barnych B, Cui Y, Xu ZL, Hammock BD, Gee SJ. VHH antibodies: emerging reagents for the analysis of environmental chemicals. Analytical and Bioanalytical Chemistry. PMID 27209591 DOI: 10.1007/s00216-016-9585-x  1
2016 Shu M, Xu Y, Liu X, Li Y, He Q, Tu Z, Fu J, Gee SJ, Hammock BD. Anti-idiotypic nanobody-alkaline phosphatase fusion proteins: Development of a one-step competitive enzyme immunoassay for fumonisin B1 detection in cereal. Analytica Chimica Acta. 924: 53-9. PMID 27181644 DOI: 10.1016/j.aca.2016.03.053  1
2016 Sirish P, Li N, Timofeyev V, Zhang XD, Wang L, Yang J, Lee KS, Bettaieb A, Ma SM, Lee JH, Su D, Lau VC, Myers RE, Lieu DK, López JE, ... ... Hammock BD, et al. Molecular Mechanisms and New Treatment Paradigm for Atrial Fibrillation. Circulation. Arrhythmia and Electrophysiology. 9. PMID 27162031 DOI: 10.1161/CIRCEP.115.003721  1
2016 Kitamura S, Hvorecny KL, Niu J, Hammock BD, Madden DR, Morisseau C. Rational design of potent and selective inhibitors of an epoxide hydrolase virulence factor from Pseudomonas aeruginosa. Journal of Medicinal Chemistry. PMID 27120257 DOI: 10.1021/acs.jmedchem.6b00173  1
2016 Sun C, Simon SI, Foster GA, Radecke CE, Hwang HT, Zhang X, Hammock BD, Chiamvimonvat N, Knowlton AA. 11,12-Epoxyecosatrienoic acids mitigate endothelial dysfunction associated with estrogen loss and aging: Role of membrane depolarization. Journal of Molecular and Cellular Cardiology. PMID 27079253 DOI: 10.1016/j.yjmcc.2016.03.019  1
2016 Ramsden CE, Ringel A, Majchrzak-Hong SF, Yang J, Blanchard H, Zamora D, Loewke JD, Rapoport SI, Hibbeln JR, Davis JM, Hammock BD, Taha AY. Dietary linoleic acid-induced alterations in pro- and anti-nociceptive lipid autacoids: Implications for idiopathic pain syndromes? Molecular Pain. 12. PMID 27030719 DOI: 10.1177/1744806916636386  0.56
2016 Goswami SK, Wan D, Yang J, Trindade da Silva CA, Morisseau C, Kodani SD, Yang GY, Inceoglu B, Hammock BD. Anti-ulcer efficacy of soluble epoxide hydrolase inhibitor TPPU on diclofenac sodium induced intestinal ulcers. The Journal of Pharmacology and Experimental Therapeutics. PMID 26989141 DOI: 10.1124/jpet.116.232108  0.64
2016 Ren Q, Ma M, Ishima T, Morisseau C, Yang J, Wagner KM, Zhang JC, Yang C, Yao W, Dong C, Han M, Hammock BD, Hashimoto K. Gene deficiency and pharmacological inhibition of soluble epoxide hydrolase confers resilience to repeated social defeat stress. Proceedings of the National Academy of Sciences of the United States of America. PMID 26976569 DOI: 10.1073/pnas.1601532113  1
2016 El-Sheikh el-SA, Kamita SG, Hammock BD. Effects of juvenile hormone (JH) analog insecticides on larval development and JH esterase activity in two spodopterans. Pesticide Biochemistry and Physiology. 128: 30-6. PMID 26969437 DOI: 10.1016/j.pestbp.2015.10.008  1
2016 Zhou Y, Yang J, Sun GY, Liu T, Duan JX, Zhou HF, Lee KS, Hammock BD, Fang X, Jiang JX, Guan CX. Erratum to: Soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea attenuates bleomycin-induced pulmonary fibrosis in mice. Cell and Tissue Research. PMID 26946414 DOI: 10.1007/s00441-016-2379-9  0.56
2016 Ahn KC, Ranganathan A, Bever CR, Hwang SH, Holland EB, Morisseau K, Pessah IN, Hammock BD, Gee SJ. Detection of the Antimicrobial Triclosan in Environmental Samples by Immunoassay. Environmental Science & Technology. PMID 26937944 DOI: 10.1021/acs.est.5b05357  1
2016 Zhao Y, Wan D, Yang J, Hammock BD, Ortiz De Montellano PR. Catalytic Activities of Tumor-Specific Human Cytochrome P450 CYP2W1 Towards Endogenous Substrates. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 26936974 DOI: 10.1124/dmd.116.069633  0.56
2016 Kim J, Ulu A, Wan D, Yang J, Hammock BD, Weiss RH. Addition of DHA synergistically enhances the efficacy of regorafenib for kidney cancer therapy. Molecular Cancer Therapeutics. PMID 26921392 DOI: 10.1158/1535-7163.MCT-15-0847  1
2016 Tong X, Khandelwal AR, Wu X, Xu Z, Yu W, Chen C, Zhao W, Yang J, Qin Z, Weisbrod RM, Seta F, Ago T, Lee KS, Hammock BD, Sadoshima J, et al. Pro-atherogenic role of smooth muscle Nox4-based NADPH oxidase. Journal of Molecular and Cellular Cardiology. PMID 26812119 DOI: 10.1016/j.yjmcc.2016.01.020  1
2016 Chen CC, Xing L, Stark M, Ou T, Holla P, Xiao K, Kamita SG, Hammock BD, Lam K, Cheng RH. Chemically activatable viral capsid functionalized for cancer targeting. Nanomedicine (London, England). PMID 26786134 DOI: 10.2217/nnm.15.207  1
2016 Liao J, Hwang SH, Li H, Liu JY, Hammock BD, Yang GY. Inhibition of Chronic Pancreatitis and Murine Pancreatic Intraepithelial Neoplasia by a Dual Inhibitor of c-RAF and Soluble Epoxide Hydrolase in LSL-KrasG12D/Pdx-1-Cre Mice. Anticancer Research. 36: 27-37. PMID 26722025  0.52
2016 Liao J, Hwang SH, Li H, Liu JY, Hammock BD, Yang GY. Inhibition of chronic pancreatitis and murine pancreatic intraepithelial neoplasia by a dual inhibitor of c-RAF and soluble epoxide hydrolase in LSL-KrasG12D/Pdx-1-Cre mice Anticancer Research. 36: 27-38.  1
2016 Červenka L, Melenovský V, Husková Z, Sporková A, Bürgelová M, Škaroupková P, Hwang SH, Hammock BD, Imig JD, Sadowski J. Inhibition of soluble epoxide hydrolase does not improve the course of congestive heart failure and the development of renal dysfunction in rats with volume overload induced by aorto-caval fistula Physiological Research. 64: 857-873.  1
2015 Nording ML, Yang J, Hoang L, Zamora V, Uyeminami D, Espiritu I, Pinkerton KE, Hammock BD, Luria A. Bioactive lipid profiling reveals drug target engagement of a soluble epoxide hydrolase inhibitor in a murine model of tobacco smoke exposure. Journal of Metabolomics. 1. PMID 27076918 DOI: 10.7243/2059-0008-1-1  0.56
2015 Liao J, Hwang SH, Li H, Yang Y, Yang J, Wecksler AT, Liu JY, Hammock BD, Yang GY. Inhibition of mutant Kras(G12D) -initiated murine pancreatic carcinoma growth by a dual c-Raf and soluble epoxide hydrolase inhibitor t-CUPM. Cancer Letters. PMID 26683769 DOI: 10.1016/j.canlet.2015.11.042  1
2015 Berthelot CC, Kamita SG, Sacchi R, Yang J, Nording ML, Georgi K, Hegedus Karbowski C, German JB, Weiss RH, Hogg RJ, Hammock BD, Zivkovic AM. Changes in PTGS1 and ALOX12 Gene Expression in Peripheral Blood Mononuclear Cells Are Associated with Changes in Arachidonic Acid, Oxylipins, and Oxylipin/Fatty Acid Ratios in Response to Omega-3 Fatty Acid Supplementation. Plos One. 10: e0144996. PMID 26672987 DOI: 10.1371/journal.pone.0144996  1
2015 Rossotti MA, Pirez M, González-Techera A, Cui Y, Bever CR, Lee KS, Morisseau C, Leizagoyen C, Gee SJ, Hammock BD, Gonzalez-Sapienza GG. A method for sorting and pairwise selection of nanobodies for the development of highly sensitive sandwich immunoassays. Analytical Chemistry. PMID 26544909 DOI: 10.1021/acs.analchem.5b03561  1
2015 Goswami SK, Inceoglu B, Yang J, Wan D, Kodani SD, da Silva CA, Morisseau C, Hammock BD. Omeprazole increases the efficacy of a soluble epoxide hydrolase inhibitor in a PGE2 induced pain model. Toxicology and Applied Pharmacology. PMID 26522832 DOI: 10.1016/j.taap.2015.10.018  1
2015 Burmistrov V, Morisseau C, Danilov D, Harris TR, Dalinger I, Vatsadze I, Shkineva T, Butov GM, Hammock BD. 1,3-Disubstituted and 1,3,3-trisubstituted adamantyl-ureas with isoxazole as soluble epoxide hydrolase inhibitors. Bioorganic & Medicinal Chemistry Letters. 25: 5514-9. PMID 26520661 DOI: 10.1016/j.bmcl.2015.10.066  1
2015 Kim IH, Park YK, Nishiwaki H, Hammock BD, Nishi K. Structure-activity relationships of amide-phosphonate derivatives as inhibitors of the human soluble epoxide hydrolase. Bioorganic & Medicinal Chemistry. 23: 7199-210. PMID 26507430 DOI: 10.1016/j.bmc.2015.10.016  0.48
2015 Liu JY, Tsai HJ, Morisseau C, Lango J, Hwang SH, Watanabe T, Kim IH, Hammock BD. In vitro and in vivo metabolism of N-adamantyl substituted urea-based soluble epoxide hydrolase inhibitors. Biochemical Pharmacology. PMID 26494425 DOI: 10.1016/j.bcp.2015.10.013  1
2015 Deng LM, Li XP, Xu DY, Morisseau C, Chiamvimonvat N, Hammock BD. Aerobic exercise-based rehabilitation affects the activities of progenitor endothelial cells through EETs pathway. Medical Hypotheses. PMID 26454561 DOI: 10.1016/j.mehy.2015.09.027  1
2015 Lu X, Elizondo RA, Nielsen R, Christensen EI, Yang J, Hammock BD, Watsky MA. Vitamin D in Tear Fluid. Investigative Ophthalmology & Visual Science. 56: 5880-5887. PMID 26348637 DOI: 10.1167/iovs.15-17177  1
2015 Hua X, Zhou L, Feng L, Ding Y, Shi H, Wang L, Gee SJ, Hammock BD, Wang M. Competitive and noncompetitive phage immunoassays for the determination of benzothiostrobin. Analytica Chimica Acta. 890: 150-6. PMID 26347177 DOI: 10.1016/j.aca.2015.07.056  1
2015 Zhou Y, Sun GY, Liu T, Duan JX, Zhou HF, Lee KS, Hammock BD, Fang X, Jiang JX, Guan CX. Soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3- (1-propionylpiperidin-4-yl) urea attenuates bleomycin-induced pulmonary fibrosis in mice. Cell and Tissue Research. PMID 26310139 DOI: 10.1007/s00441-015-2262-0  1
2015 Ranganathan A, Gee SJ, Hammock BD. An immunoassay for the detection of triclosan-O-glucuronide, a primary human urinary metabolite of triclosan. Analytical and Bioanalytical Chemistry. PMID 26255293 DOI: 10.1007/s00216-015-8918-5  0.8
2015 Cui Y, Li D, Morisseau C, Dong JX, Yang J, Wan D, Rossotti MA, Gee SJ, González-Sapienza GG, Hammock BD. Heavy chain single-domain antibodies to detect native human soluble epoxide hydrolase. Analytical and Bioanalytical Chemistry. PMID 26229025 DOI: 10.1007/s00216-015-8889-6  1
2015 Vasylieva N, Ahn KC, Barnych B, Gee SJ, Hammock BD. Development of an Immunoassay for the Detection of the Phenylpyrazole Insecticide Fipronil. Environmental Science & Technology. PMID 26196357 DOI: 10.1021/acs.est.5b01005  1
2015 Hwang VJ, Kim J, Rand A, Yang C, Sturdivant S, Hammock B, Bell PD, Guay-Woodford LM, Weiss RH. The cpk model of recessive PKD shows glutamine-dependence associated with the production of the oncometabolite 2-hydroxyglutarate. American Journal of Physiology. Renal Physiology. ajprenal.00238.2015. PMID 26155843 DOI: 10.1152/ajprenal.00238.2015  1
2015 Inceoglu B, Bettaieb A, Trindade da Silva CA, Lee KS, Haj FG, Hammock BD. Endoplasmic reticulum stress in the peripheral nervous system is a significant driver of neuropathic pain. Proceedings of the National Academy of Sciences of the United States of America. PMID 26150506 DOI: 10.1073/pnas.1510137112  1
2015 Bahl CD, Hvorecny KL, Bomberger JM, Stanton BA, Hammock BD, Morisseau C, Madden DR. Inhibiting an epoxide hydrolase virulence factor from Pseudomonas aeruginosa protects CFTR. Angewandte Chemie (International Ed. in English). PMID 26136396 DOI: 10.1002/anie.201503983  1
2015 Ostermann AI, Herbers J, Willenberg I, Chen R, Hwang SH, Greite R, Morisseau C, Gueler F, Hammock BD, Schebb NH. Oral treatment of rodents with soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea (TPPU): Resulting drug levels and modulation of oxylipin pattern. Prostaglandins & Other Lipid Mediators. PMID 26117215 DOI: 10.1016/j.prostaglandins.2015.06.005  0.64
2015 Thomson S, Edin ML, Lih FB, Davies M, Yaqoob MM, Hammock BD, Gilroy D, Zeldin DC, Bishop-Bailey D. Intimal smooth muscle cells are a source but not a sensor of anti-inflammatory CYP450 derived oxylipins. Biochemical and Biophysical Research Communications. PMID 26086108 DOI: 10.1016/j.bbrc.2015.06.012  1
2015 Qin J, Sun D, Jiang H, Kandhi S, Froogh G, Hwang SH, Hammock BD, Wolin MS, Thompson CI, Hintze TH, Huang A. Inhibition of soluble epoxide hydrolase increases coronary perfusion in mice. Physiological Reports. 3. PMID 26071213 DOI: 10.14814/phy2.12427  0.52
2015 Walkowska A, Kuczeriszka M, Sadowski J, Olszyñski KH, Dobrowolski L, ?ervenka L, Hammock BD, Kompanowska-Jezierska E. High Salt Intake Increases Blood Pressure in Normal Rats: Putative Role of 20-HETE and No Evidence on Changes in Renal Vascular Reactivity. Kidney & Blood Pressure Research. 40: 323-34. PMID 26067851 DOI: 10.1159/000368508  1
2015 ?ervenka L, Melenovský V, Husková Z, Sporková A, Bürgelová M, Škaroupková P, Hwang SH, Hammock BD, Imig JD, Sadowski J. Inhibition of soluble epoxide hydrolase does not improve the course of congestive heart failure and the development of renal dysfunction in rats with volume overload induced by aorto-caval fistula. Physiological Research / Academia Scientiarum Bohemoslovaca. PMID 26047375  0.52
2015 Bettaieb A, Chahed S, Bachaalany S, Griffey S, Hammock BD, Haj FG. Soluble Epoxide Hydrolase Pharmacological Inhibition Ameliorates Experimental Acute Pancreatitis in Mice. Molecular Pharmacology. 88: 281-90. PMID 25993999 DOI: 10.1124/mol.114.097501  1
2015 Yin W, Hua X, Liu X, Shi H, Gee SJ, Wang M, Hammock BD. Development of an enzyme-linked immunosorbent assay for thiacloprid in soil and agro-products with phage-displayed peptide. Analytical Biochemistry. 481: 27-32. PMID 25908560 DOI: 10.1016/j.ab.2015.04.015  1
2015 Bruun DA, Cao Z, Inceoglu B, Vito ST, Austin AT, Hulsizer S, Hammock BD, Tancredi DJ, Rogawski MA, Pessah IN, Lein PJ. Combined treatment with diazepam and allopregnanolone reverses tetramethylenedisulfotetramine (TETS)-induced calcium dysregulation in cultured neurons and protects TETS-intoxicated mice against lethal seizures. Neuropharmacology. 95: 332-42. PMID 25882826 DOI: 10.1016/j.neuropharm.2015.03.035  1
2015 Sasso O, Wagner K, Morisseau C, Inceoglu B, Hammock BD, Piomelli D. Peripheral FAAH and soluble epoxide hydrolase inhibitors are synergistically antinociceptive. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 97: 7-15. PMID 25882247 DOI: 10.1016/j.phrs.2015.04.001  1
2015 Fahrmann J, Grapov D, Yang J, Hammock B, Fiehn O, Bell GI, Hara M. Systemic alterations in the metabolome of diabetic NOD mice delineate increased oxidative stress accompanied by reduced inflammation and hypertriglyceremia. American Journal of Physiology. Endocrinology and Metabolism. 308: E978-89. PMID 25852003 DOI: 10.1152/ajpendo.00019.2015  1
2015 Wang J, Majkova Z, Bever CR, Yang J, Gee SJ, Li J, Xu T, Hammock BD. One-step immunoassay for tetrabromobisphenol a using a camelid single domain antibody-alkaline phosphatase fusion protein. Analytical Chemistry. 87: 4741-8. PMID 25849972 DOI: 10.1021/ac504735p  1
2015 Harris TR, Bettaieb A, Kodani S, Dong H, Myers R, Chiamvimonvat N, Haj FG, Hammock BD. Inhibition of soluble epoxide hydrolase attenuates hepatic fibrosis and endoplasmic reticulum stress induced by carbon tetrachloride in mice. Toxicology and Applied Pharmacology. 286: 102-11. PMID 25827057 DOI: 10.1016/j.taap.2015.03.022  1
2015 Shih PB, Yang J, Morisseau C, German JB, Zeeland AA, Armando AM, Quehenberger O, Bergen AW, Magistretti P, Berrettini W, Halmi KA, Schork N, Hammock BD, Kaye W. Dysregulation of soluble epoxide hydrolase and lipidomic profiles in anorexia nervosa. Molecular Psychiatry. PMID 25824304 DOI: 10.1038/mp.2015.26  1
2015 Kodani SD, Hammock BD. The 2014 Bernard B. Brodie award lecture-epoxide hydrolases: drug metabolism to therapeutics for chronic pain. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 788-802. PMID 25762541 DOI: 10.1124/dmd.115.063339  1
2015 Shen L, Peng H, Peng R, Fan Q, Zhao S, Xu D, Morisseau C, Chiamvimonvat N, Hammock BD. Inhibition of soluble epoxide hydrolase in mice promotes reverse cholesterol transport and regression of atherosclerosis. Atherosclerosis. 239: 557-65. PMID 25733327 DOI: 10.1016/j.atherosclerosis.2015.02.014  1
2015 Saito Y, Kamita SG, Hammock BD, Kunimi Y, Inoue MN, Nakai M. Juvenile hormone (JH) esterase activity but not JH epoxide hydrolase activity is downregulated in larval Adoxophyes honmai following nucleopolyhedroviruses infection. Journal of Insect Physiology. PMID 25727179 DOI: 10.1016/j.jinsphys.2015.02.005  1
2015 Nollmann FI, Heinrich AK, Brachmann AO, Morisseau C, Mukherjee K, Casanova-Torres ÁM, Strobl F, Kleinhans D, Kinski S, Schultz K, Beeton ML, Kaiser M, Chu YY, Phan Ke L, Thanwisai A, ... ... Hammock BD, et al. A photorhabdus natural product inhibits insect juvenile hormone epoxide hydrolase. Chembiochem : a European Journal of Chemical Biology. 16: 766-71. PMID 25711603 DOI: 10.1002/cbic.201402650  1
2015 Xu J, Morisseau C, Yang J, Mamatha DM, Hammock BD. Epoxide hydrolase activities and epoxy fatty acids in the mosquito Culex quinquefasciatus. Insect Biochemistry and Molecular Biology. 59: 41-9. PMID 25686802 DOI: 10.1016/j.ibmb.2015.02.004  1
2015 Kitamura S, Morisseau C, Inceoglu B, Kamita SG, De Nicola GR, Nyegue M, Hammock BD. Potent natural soluble epoxide hydrolase inhibitors from Pentadiplandra brazzeana baillon: synthesis, quantification, and measurement of biological activities in vitro and in vivo. Plos One. 10: e0117438. PMID 25659109 DOI: 10.1371/journal.pone.0117438  1
2015 López-Vicario C, Alcaraz-Quiles J, García-Alonso V, Rius B, Hwang SH, Titos E, Lopategi A, Hammock BD, Arroyo V, Clària J. Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: role for omega-3 epoxides. Proceedings of the National Academy of Sciences of the United States of America. 112: 536-41. PMID 25550510 DOI: 10.1073/pnas.1422590112  1
2015 Liu X, Xu Y, Wan DB, Xiong YH, He ZY, Wang XX, Gee SJ, Ryu D, Hammock BD. Development of a nanobody-alkaline phosphatase fusion protein and its application in a highly sensitive direct competitive fluorescence enzyme immunoassay for detection of ochratoxin A in cereal. Analytical Chemistry. 87: 1387-94. PMID 25531426 DOI: 10.1021/ac504305z  1
2015 Shihadih DS, Harris TR, Yang J, Merzlikin O, Lee KS, Hammock BD, Morisseau C. Identification of potent inhibitors of the chicken soluble epoxide hydrolase. Bioorganic & Medicinal Chemistry Letters. 25: 276-9. PMID 25479771 DOI: 10.1016/j.bmcl.2014.11.053  0.64
2015 Flannery BM, Silverman JL, Bruun DA, Puhger KR, McCoy MR, Hammock BD, Crawley JN, Lein PJ. Behavioral assessment of NIH Swiss mice acutely intoxicated with tetramethylenedisulfotetramine. Neurotoxicology and Teratology. 47: 36-45. PMID 25446016 DOI: 10.1016/j.ntt.2014.10.008  1
2015 Wecksler AT, Hwang SH, Liu JY, Wettersten HI, Morisseau C, Wu J, Weiss RH, Hammock BD. Biological evaluation of a novel sorafenib analogue, t-CUPM. Cancer Chemotherapy and Pharmacology. 75: 161-71. PMID 25413440 DOI: 10.1007/s00280-014-2626-2  1
2015 Kim J, Yoon SP, Toews ML, Imig JD, Hwang SH, Hammock BD, Padanilam BJ. Pharmacological inhibition of soluble epoxide hydrolase prevents renal interstitial fibrogenesis in obstructive nephropathy. American Journal of Physiology. Renal Physiology. 308: F131-9. PMID 25377915 DOI: 10.1152/ajprenal.00531.2014  1
2015 Yang J, Bratt J, Franzi L, Liu JY, Zhang G, Zeki AA, Vogel CF, Williams K, Dong H, Lin Y, Hwang SH, Kenyon NJ, Hammock BD. Soluble epoxide hydrolase inhibitor attenuates inflammation and airway hyperresponsiveness in mice. American Journal of Respiratory Cell and Molecular Biology. 52: 46-55. PMID 24922186 DOI: 10.1165/rcmb.2013-0440OC  1
2015 Kim IH, Park YK, Nishiwaki H, Hammock BD, Nishi K. Structure-activity relationships of amide-phosphonate derivatives as inhibitors of the human soluble epoxide hydrolase Bioorganic and Medicinal Chemistry. 23: 7199-7210. DOI: 10.1016/j.bmc.2015.10.016  1
2015 Ranganathan A, Gee SJ, Hammock BD. An immunoassay for the detection of triclosan-O-glucuronide, a primary human urinary metabolite of triclosan Analytical and Bioanalytical Chemistry. DOI: 10.1007/s00216-015-8918-5  1
2014 Hua X, Liu X, Shi H, Wang Y, Kim HJ, Gee SJ, Wang M, Liu F, Hammock BD. Development of a heterologous enzyme-linked immunosorbent assay for organophosphorus pesticides with phage-borne peptide. Rsc Advances. 4: 42445-42453. PMID 26290688 DOI: 10.1039/C4RA07059C  0.8
2014 Chen A, Wang R, Bever CR, Xing S, Hammock BD, Pan T. Smartphone-interfaced lab-on-a-chip devices for field-deployable enzyme-linked immunosorbent assay. Biomicrofluidics. 8: 064101. PMID 25553178 DOI: 10.1063/1.4901348  1
2014 Panigrahy D, Hammock B. Editorial: 15th International Winter Eicosanoid Conference Prostaglandins & Other Lipid Mediators. 113: 1. PMID 25453874 DOI: 10.1016/j.prostaglandins.2014.10.004  1
2014 Vito ST, Austin AT, Banks CN, Inceoglu B, Bruun DA, Zolkowska D, Tancredi DJ, Rogawski MA, Hammock BD, Lein PJ. Post-exposure administration of diazepam combined with soluble epoxide hydrolase inhibition stops seizures and modulates neuroinflammation in a murine model of acute TETS intoxication. Toxicology and Applied Pharmacology. 281: 185-94. PMID 25448683 DOI: 10.1016/j.taap.2014.10.001  1
2014 Bettaieb A, Chahed S, Tabet G, Yang J, Morisseau C, Griffey S, Hammock BD, Haj FG. Effects of soluble epoxide hydrolase deficiency on acute pancreatitis in mice. Plos One. 9: e113019. PMID 25402489 DOI: 10.1371/journal.pone.0113019  1
2014 Piomelli D, Hohmann AG, Seybold V, Hammock BD. A lipid gate for the peripheral control of pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 15184-91. PMID 25392487 DOI: 10.1523/JNEUROSCI.3475-14.2014  1
2014 McAndrew R, Pruitt RN, Kamita SG, Pereira JH, Majumdar D, Hammock BD, Adams PD, Ronald PC. Structure of the OsSERK2 leucine-rich repeat extracellular domain. Acta Crystallographica. Section D, Biological Crystallography. 70: 3080-6. PMID 25372696 DOI: 10.1107/S1399004714021178  1
2014 Samokhvalov V, Zlobine I, Jamieson KL, Jurasz P, Chen C, Lee KS, Hammock BD, Seubert JM. PPARδ signaling mediates the cytotoxicity of DHA in H9c2 cells. Toxicology Letters. 232: 10-20. PMID 25300478 DOI: 10.1016/j.toxlet.2014.09.029  1
2014 Wagner K, Vito S, Inceoglu B, Hammock BD. The role of long chain fatty acids and their epoxide metabolites in nociceptive signaling. Prostaglandins & Other Lipid Mediators. 113: 2-12. PMID 25240260 DOI: 10.1016/j.prostaglandins.2014.09.001  1
2014 Sporková A, Jíchová S, Husková Z, Kopkan L, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Kompanowska-Jezierska E, Sadowski J, Kramer HJ, Cervenka L. Different mechanisms of acute versus long-term antihypertensive effects of soluble epoxide hydrolase inhibition: studies in Cyp1a1-Ren-2 transgenic rats. Clinical and Experimental Pharmacology & Physiology. 41: 1003-13. PMID 25224811 DOI: 10.1111/1440-1681.12310  1
2014 Terry CM, Carlson ML, He Y, Ulu A, Morisseau C, Blumenthal DK, Hammock BD, Cheung AK. Aberrant soluble epoxide hydrolase and oxylipin levels in a porcine arteriovenous graft stenosis model. Journal of Vascular Research. 51: 269-82. PMID 25196102 DOI: 10.1159/000365251  1
2014 Xu J, Morisseau C, Hammock BD. Expression and characterization of an epoxide hydrolase from Anopheles gambiae with high activity on epoxy fatty acids. Insect Biochemistry and Molecular Biology. 54: 42-52. PMID 25173592 DOI: 10.1016/j.ibmb.2014.08.004  1
2014 Kim J, Imig JD, Yang J, Hammock BD, Padanilam BJ. Inhibition of soluble epoxide hydrolase prevents renal interstitial fibrosis and inflammation. American Journal of Physiology. Renal Physiology. 307: F971-80. PMID 25164080 DOI: 10.1152/ajprenal.00256.2014  1
2014 Ono E, Dutile S, Kazani S, Wechsler ME, Yang J, Hammock BD, Douda DN, Tabet Y, Khaddaj-Mallat R, Sirois M, Sirois C, Rizcallah E, Rousseau E, Martin R, Sutherland ER, et al. Lipoxin generation is related to soluble epoxide hydrolase activity in severe asthma. American Journal of Respiratory and Critical Care Medicine. 190: 886-97. PMID 25162465 DOI: 10.1164/rccm.201403-0544OC  1
2014 Despa S, Sharma S, Harris TR, Dong H, Li N, Chiamvimonvat N, Taegtmeyer H, Margulies KB, Hammock BD, Despa F. Cardioprotection by controlling hyperamylinemia in a "humanized" diabetic rat model. Journal of the American Heart Association. 3. PMID 25146704 DOI: 10.1161/JAHA.114.001015  1
2014 Hua X, Yin W, Shi H, Li M, Wang Y, Wang H, Ye Y, Kim HJ, Gee SJ, Wang M, Liu F, Hammock BD. Development of phage immuno-loop-mediated isothermal amplification assays for organophosphorus pesticides in agro-products. Analytical Chemistry. 86: 8441-7. PMID 25135320 DOI: 10.1021/ac5020657  1
2014 Lee KS, Liu JY, Wagner KM, Pakhomova S, Dong H, Morisseau C, Fu SH, Yang J, Wang P, Ulu A, Mate CA, Nguyen LV, Hwang SH, Edin ML, Mara AA, ... ... Hammock BD, et al. Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy. Journal of Medicinal Chemistry. 57: 7016-30. PMID 25079952 DOI: 10.1021/jm500694p  1
2014 Dong JX, Xu C, Wang H, Xiao ZL, Gee SJ, Li ZF, Wang F, Wu WJ, Shen YD, Yang JY, Sun YM, Hammock BD. Enhanced sensitive immunoassay: noncompetitive phage anti-immune complex assay for the determination of malachite green and leucomalachite green. Journal of Agricultural and Food Chemistry. 62: 8752-8. PMID 25077381 DOI: 10.1021/jf5019824  1
2014 Wang J, Bever CR, Majkova Z, Dechant JE, Yang J, Gee SJ, Xu T, Hammock BD. Heterologous antigen selection of camelid heavy chain single domain antibodies against tetrabromobisphenol A. Analytical Chemistry. 86: 8296-302. PMID 25068372 DOI: 10.1021/ac5017437  1
2014 Radhakrishnan R, Suni II, Bever CS, Hammock BD. Impedance Biosensors: Applications to Sustainability and Remaining Technical Challenges. Acs Sustainable Chemistry & Engineering. 2: 1649-1655. PMID 25068095 DOI: 10.1021/sc500106y  1
2014 Zhang G, Panigrahy D, Hwang SH, Yang J, Mahakian LM, Wettersten HI, Liu JY, Wang Y, Ingham ES, Tam S, Kieran MW, Weiss RH, Ferrara KW, Hammock BD. Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis. Proceedings of the National Academy of Sciences of the United States of America. 111: 11127-32. PMID 25024195 DOI: 10.1073/pnas.1410432111  1
2014 Gupta R, Dong Y, Solomon PD, Wettersten HI, Cheng CJ, Min JN, Henson J, Dogra SK, Hwang SH, Hammock BD, Zhu LJ, Reddel RR, Saltzman WM, Weiss RH, Chang S, et al. Synergistic tumor suppression by combined inhibition of telomerase and CDKN1A. Proceedings of the National Academy of Sciences of the United States of America. 111: E3062-71. PMID 25024194 DOI: 10.1073/pnas.1411370111  1
2014 Wang W, Zhu J, Lyu F, Panigrahy D, Ferrara KW, Hammock B, Zhang G. ω-3 polyunsaturated fatty acids-derived lipid metabolites on angiogenesis, inflammation and cancer. Prostaglandins & Other Lipid Mediators. 113: 13-20. PMID 25019221 DOI: 10.1016/j.prostaglandins.2014.07.002  1
2014 Sarnpitak P, Mujumdar P, Morisseau C, Hwang SH, Hammock B, Iurchenko V, Zozulya S, Gavalas A, Geronikaki A, Ivanenkov Y, Krasavin M. Potent, orally available, selective COX-2 inhibitors based on 2-imidazoline core. European Journal of Medicinal Chemistry. 84: 160-72. PMID 25016374 DOI: 10.1016/j.ejmech.2014.07.023  1
2014 Bever CR, Majkova Z, Radhakrishnan R, Suni I, McCoy M, Wang Y, Dechant J, Gee S, Hammock BD. Development and utilization of camelid VHH antibodies from alpaca for 2,2',4,4'-tetrabrominated diphenyl ether detection. Analytical Chemistry. 86: 7875-82. PMID 25005746 DOI: 10.1021/ac501807j  1
2014 Liu X, Xu Y, Xiong YH, Tu Z, Li YP, He ZY, Qiu YL, Fu JH, Gee SJ, Hammock BD. VHH phage-based competitive real-time immuno-polymerase chain reaction for ultrasensitive detection of ochratoxin A in cereal. Analytical Chemistry. 86: 7471-7. PMID 24992514 DOI: 10.1021/ac501202d  1
2014 Wagner K, Yang J, Inceoglu B, Hammock BD. Soluble epoxide hydrolase inhibition is antinociceptive in a mouse model of diabetic neuropathy. The Journal of Pain : Official Journal of the American Pain Society. 15: 907-14. PMID 24924124 DOI: 10.1016/j.jpain.2014.05.008  1
2014 Zhao C, Hwang SH, Buchholz BA, Carpenter TS, Lightstone FC, Lightstone F, Yang J, Hammock BD, Casida JE. GABAA receptor target of tetramethylenedisulfotetramine. Proceedings of the National Academy of Sciences of the United States of America. 111: 8607-12. PMID 24912155 DOI: 10.1073/pnas.1407379111  1
2014 Schebb NH, Ostermann AI, Yang J, Hammock BD, Hahn A, Schuchardt JP. Comparison of the effects of long-chain omega-3 fatty acid supplementation on plasma levels of free and esterified oxylipins. Prostaglandins & Other Lipid Mediators. 113: 21-9. PMID 24880049 DOI: 10.1016/j.prostaglandins.2014.05.002  1
2014 Charles RL, Rudyk O, Prysyazhna O, Kamynina A, Yang J, Morisseau C, Hammock BD, Freeman BA, Eaton P. Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase. Proceedings of the National Academy of Sciences of the United States of America. 111: 8167-72. PMID 24843165 DOI: 10.1073/pnas.1402965111  1
2014 Morisseau C, Wecksler AT, Deng C, Dong H, Yang J, Lee KS, Kodani SD, Hammock BD. Effect of soluble epoxide hydrolase polymorphism on substrate and inhibitor selectivity and dimer formation. Journal of Lipid Research. 55: 1131-1138. PMID 24771868 DOI: 10.1194/jlr.M049718  1
2014 Schebb NH, Muvvala JB, Morin D, Buckpitt AR, Hammock BD, Rice RH. Metabolic activation of the antibacterial agent triclocarban by cytochrome P450 1A1 yielding glutathione adducts. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 1098-102. PMID 24733789 DOI: 10.1124/dmd.114.058206  1
2014 Trunnelle KJ, Bennett DH, Ahn KC, Schenker MB, Tancredi DJ, Gee SJ, Stoecklin-Marois MT, Hammock BD. Concentrations of the urinary pyrethroid metabolite 3-phenoxybenzoic acid in farm worker families in the MICASA study. Environmental Research. 131: 153-9. PMID 24721133 DOI: 10.1016/j.envres.2014.03.003  1
2014 Li L, Li N, Pang W, Zhang X, Hammock BD, Ai D, Zhu Y. Opposite effects of gene deficiency and pharmacological inhibition of soluble epoxide hydrolase on cardiac fibrosis. Plos One. 9: e94092. PMID 24718617 DOI: 10.1371/journal.pone.0094092  1
2014 Shrestha A, Krishnamurthy PT, Thomas P, Hammock BD, Hwang SH. Soluble epoxide hydrolase inhibitor, t-TUCB, protects against myocardial ischaemic injury in rats. The Journal of Pharmacy and Pharmacology. 66: 1251-8. PMID 24697323 DOI: 10.1111/jphp.12251  1
2014 Ulu A, Stephen Lee KS, Miyabe C, Yang J, Hammock BG, Dong H, Hammock BD. An omega-3 epoxide of docosahexaenoic acid lowers blood pressure in angiotensin-II-dependent hypertension. Journal of Cardiovascular Pharmacology. 64: 87-99. PMID 24691274 DOI: 10.1097/FJC.0000000000000094  0.36
2014 Burmistrov V, Morisseau C, Lee KS, Shihadih DS, Harris TR, Butov GM, Hammock BD. Symmetric adamantyl-diureas as soluble epoxide hydrolase inhibitors. Bioorganic & Medicinal Chemistry Letters. 24: 2193-7. PMID 24685540 DOI: 10.1016/j.bmcl.2014.03.016  1
2014 Schuchardt JP, Schneider I, Willenberg I, Yang J, Hammock BD, Hahn A, Schebb NH. Increase of EPA-derived hydroxy, epoxy and dihydroxy fatty acid levels in human plasma after a single dose of long-chain omega-3 PUFA. Prostaglandins & Other Lipid Mediators. 109: 23-31. PMID 24667634 DOI: 10.1016/j.prostaglandins.2014.03.001  1
2014 Kálai T, Altman R, Maezawa I, Balog M, Morisseau C, Petrlova J, Hammock BD, Jin LW, Trudell JR, Voss JC, Hideg K. Synthesis and functional survey of new Tacrine analogs modified with nitroxides or their precursors. European Journal of Medicinal Chemistry. 77: 343-50. PMID 24657571 DOI: 10.1016/j.ejmech.2014.03.026  1
2014 Sun D, Cuevas AJ, Gotlinger K, Hwang SH, Hammock BD, Schwartzman ML, Huang A. Soluble epoxide hydrolase-dependent regulation of myogenic response and blood pressure. American Journal of Physiology. Heart and Circulatory Physiology. 306: H1146-53. PMID 24561863 DOI: 10.1152/ajpheart.00920.2013  1
2014 Wecksler AT, Hwang SH, Wettersten HI, Gilda JE, Patton A, Leon LJ, Carraway KL, Gomes AV, Baar K, Weiss RH, Hammock BD. Novel sorafenib-based structural analogues: in-vitro anticancer evaluation of t-MTUCB and t-AUCMB. Anti-Cancer Drugs. 25: 433-46. PMID 24525589 DOI: 10.1097/CAD.0000000000000079  1
2014 Kujal P, ?ertíková Chábová V, Škaroupková P, Husková Z, Vernerová Z, Kramer HJ, Walkowska A, Kompanowska-Jezierska E, Sadowski J, Kitada K, Nishiyama A, Hwang SH, Hammock BD, Imig JD, ?ervenka L. Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats. Clinical and Experimental Pharmacology & Physiology. 41: 227-37. PMID 24471737 DOI: 10.1111/1440-1681.12204  1
2014 Kim IH, Lee IH, Nishiwaki H, Hammock BD, Nishi K. Structure-activity relationships of substituted oxyoxalamides as inhibitors of the human soluble epoxide hydrolase. Bioorganic & Medicinal Chemistry. 22: 1163-75. PMID 24433964 DOI: 10.1016/j.bmc.2013.12.027  1
2014 Schuchardt JP, Schmidt S, Kressel G, Willenberg I, Hammock BD, Hahn A, Schebb NH. Modulation of blood oxylipin levels by long-chain omega-3 fatty acid supplementation in hyper- and normolipidemic men. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 90: 27-37. PMID 24411718 DOI: 10.1016/j.plefa.2013.12.008  1
2014 Zhang G, Kodani S, Hammock BD. Stabilized epoxygenated fatty acids regulate inflammation, pain, angiogenesis and cancer. Progress in Lipid Research. 53: 108-23. PMID 24345640 DOI: 10.1016/j.plipres.2013.11.003  1
2014 Thiphom S, Prapamontol T, Chantara S, Mangklabruks A, Suphavilai C, Ahn KC, Gee SJ, Hammock BD. Determination of the pyrethroid insecticide metabolite 3-PBA in plasma and urine samples from farmer and consumer groups in northern Thailand. Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes. 49: 15-22. PMID 24138464 DOI: 10.1080/03601234.2013.836862  1
2014 Zhao C, Hwang SH, Buchholz BA, Carpenter TS, Lightstone F, Yang J, Hammock BD, Casida JE. GABAA receptor target of tetramethylenedisulfotetramine (Proceedings of the National Academy of Sciences of the United States of America (2014) 111 (8607-8612) DOI: 10.1073/pnas.1407379111) Proceedings of the National Academy of Sciences of the United States of America. 111: 11223. DOI: 10.1073/pnas.1412593111  1
2014 Hua X, Liu X, Shi H, Wang Y, Kim HJ, Gee SJ, Wang M, Liu F, Hammock BD. Development of a heterologous enzyme-linked immunosorbent assay for organophosphorus pesticides with phage-borne peptide Rsc Advances. 4: 42445-42453. DOI: 10.1039/c4ra07059c  1
2013 Park EK, Mak SK, Hammock BD. Effects of cadmium chloride on mouse inner medullary collecting duct cells. Interdisciplinary Toxicology. 6: 157-8. PMID 24678254 DOI: 10.2478/intox-2013-0025  1
2013 Inceoglu B, Zolkowska D, Yoo HJ, Wagner KM, Yang J, Hackett E, Hwang SH, Lee KS, Rogawski MA, Morisseau C, Hammock BD. Epoxy fatty acids and inhibition of the soluble epoxide hydrolase selectively modulate GABA mediated neurotransmission to delay onset of seizures. Plos One. 8: e80922. PMID 24349022 DOI: 10.1371/journal.pone.0080922  1
2013 Nandety RS, Kamita SG, Hammock BD, Falk BW. Sequencing and de novo assembly of the transcriptome of the glassy-winged sharpshooter (Homalodisca vitripennis). Plos One. 8: e81681. PMID 24339955 DOI: 10.1371/journal.pone.0081681  1
2013 Zhang W, Li H, Dong H, Liao J, Hammock BD, Yang GY. Soluble epoxide hydrolase deficiency inhibits dextran sulfate sodium-induced colitis and carcinogenesis in mice. Anticancer Research. 33: 5261-71. PMID 24324059  1
2013 Chen T, Takrouri K, Hee-Hwang S, Rana S, Yefidoff-Freedman R, Halperin J, Natarajan A, Morisseau C, Hammock B, Chorev M, Aktas BH. Explorations of substituted urea functionality for the discovery of new activators of the heme-regulated inhibitor kinase. Journal of Medicinal Chemistry. 56: 9457-70. PMID 24261904 DOI: 10.1021/jm400793v  1
2013 Nording ML, Yang J, Georgi K, Hegedus Karbowski C, German JB, Weiss RH, Hogg RJ, Trygg J, Hammock BD, Zivkovic AM. Individual variation in lipidomic profiles of healthy subjects in response to omega-3 Fatty acids. Plos One. 8: e76575. PMID 24204640 DOI: 10.1371/journal.pone.0076575  1
2013 Trunnelle KJ, Bennett DH, Tancredi DJ, Gee SJ, Stoecklin-Marois MT, Hennessy-Burt TE, Hammock BD, Schenker MB. Pyrethroids in house dust from the homes of farm worker families in the MICASA study. Environment International. 61: 57-63. PMID 24096042 DOI: 10.1016/j.envint.2013.09.007  1
2013 Gardell AM, Yang J, Sacchi R, Fangue NA, Hammock BD, Kültz D. Tilapia (Oreochromis mossambicus) brain cells respond to hyperosmotic challenge by inducing myo-inositol biosynthesis. The Journal of Experimental Biology. 216: 4615-25. PMID 24072790 DOI: 10.1242/jeb.088906  1
2013 Frolov A, Yang L, Dong H, Hammock BD, Crofford LJ. Anti-inflammatory properties of prostaglandin E2: deletion of microsomal prostaglandin E synthase-1 exacerbates non-immune inflammatory arthritis in mice. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 89: 351-8. PMID 24055573 DOI: 10.1016/j.plefa.2013.08.003  1
2013 Shaik JS, Ahmad M, Li W, Rose ME, Foley LM, Hitchens TK, Graham SH, Hwang SH, Hammock BD, Poloyac SM. Soluble epoxide hydrolase inhibitor trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid is neuroprotective in rat model of ischemic stroke. American Journal of Physiology. Heart and Circulatory Physiology. 305: H1605-13. PMID 24043255 DOI: 10.1152/ajpheart.00471.2013  1
2013 Lee AR, Pechenino AS, Dong H, Hammock BD, Knowlton AA. Aging, estrogen loss and epoxyeicosatrienoic acids (EETs). Plos One. 8: e70719. PMID 23967089 DOI: 10.1371/journal.pone.0070719  1
2013 Van Bogaert I, Zhang G, Yang J, Liu JY, Ye Y, Soetaert W, Hammock BD. Preparation of 20-HETE using multifunctional enzyme type 2-negative Starmerella bombicola. Journal of Lipid Research. 54: 3215-9. PMID 23966667 DOI: 10.1194/jlr.D042226  1
2013 Wang Y, Li P, Majkova Z, Bever CR, Kim HJ, Zhang Q, Dechant JE, Gee SJ, Hammock BD. Isolation of alpaca anti-idiotypic heavy-chain single-domain antibody for the aflatoxin immunoassay. Analytical Chemistry. 85: 8298-303. PMID 23965250 DOI: 10.1021/ac4015885  1
2013 Panigrahy D, Kalish BT, Huang S, Bielenberg DR, Le HD, Yang J, Edin ML, Lee CR, Benny O, Mudge DK, Butterfield CE, Mammoto A, Mammoto T, Inceoglu B, Jenkins RL, ... ... Hammock BD, et al. Epoxyeicosanoids promote organ and tissue regeneration. Proceedings of the National Academy of Sciences of the United States of America. 110: 13528-33. PMID 23898174 DOI: 10.1073/pnas.1311565110  1
2013 Lundström SL, Yang J, Brannan JD, Haeggström JZ, Hammock BD, Nair P, O'Byrne P, Dahlén SE, Wheelock CE. Lipid mediator serum profiles in asthmatics significantly shift following dietary supplementation with omega-3 fatty acids. Molecular Nutrition & Food Research. 57: 1378-89. PMID 23824870 DOI: 10.1002/mnfr.201200827  1
2013 Smilowitz JT, Zivkovic AM, Wan YJ, Watkins SM, Nording ML, Hammock BD, German JB. Nutritional lipidomics: molecular metabolism, analytics, and diagnostics. Molecular Nutrition & Food Research. 57: 1319-35. PMID 23818328 DOI: 10.1002/mnfr.201200808  1
2013 Frolov A, Dong H, Jiang M, Yang L, Cook EC, Matnani R, Hammock BD, Crofford LJ. Niemann-pick type C2 deficiency in human fibroblasts confers robust and selective activation of prostaglandin E2 biosynthesis. The Journal of Biological Chemistry. 288: 23696-703. PMID 23814065 DOI: 10.1074/jbc.M112.445916  1
2013 Ranganathan A, Paradise GA, Hansen CA, McCoy MR, Gee SJ, Zhong P, Chang D, Hammock BD. Indirect homologous competitive enzyme-linked immunosorbent assay for the detection of a class of glycosylated dihydrochalcones. Journal of Agricultural and Food Chemistry. 61: 6964-70. PMID 23767873 DOI: 10.1021/jf401302y  1
2013 Boesten DM, Berger A, de Cock P, Dong H, Hammock BD, den Hartog GJ, Bast A. Multi-targeted mechanisms underlying the endothelial protective effects of the diabetic-safe sweetener erythritol. Plos One. 8: e65741. PMID 23755276 DOI: 10.1371/journal.pone.0065741  1
2013 Hwang SH, Wecksler AT, Zhang G, Morisseau C, Nguyen LV, Fu SH, Hammock BD. Synthesis and biological evaluation of sorafenib- and regorafenib-like sEH inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 3732-7. PMID 23726028 DOI: 10.1016/j.bmcl.2013.05.011  1
2013 Kamita SG, Oshita GH, Wang P, Morisseau C, Hammock BD, Nandety RS, Falk BW. Characterization of Hovi-mEH1, a microsomal epoxide hydrolase from the glassy-winged sharpshooter Homalodisca vitripennis. Archives of Insect Biochemistry and Physiology. 83: 171-9. PMID 23704009 DOI: 10.1002/arch.21100  1
2013 Harris TR, Hammock BD. Soluble epoxide hydrolase: gene structure, expression and deletion. Gene. 526: 61-74. PMID 23701967 DOI: 10.1016/j.gene.2013.05.008  1
2013 Schuchardt JP, Schmidt S, Kressel G, Dong H, Willenberg I, Hammock BD, Hahn A, Schebb NH. Comparison of free serum oxylipin concentrations in hyper- vs. normolipidemic men. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 89: 19-29. PMID 23694766 DOI: 10.1016/j.plefa.2013.04.001  1
2013 Morisseau C, Pakhomova S, Hwang SH, Newcomer ME, Hammock BD. Inhibition of soluble epoxide hydrolase by fulvestrant and sulfoxides. Bioorganic & Medicinal Chemistry Letters. 23: 3818-21. PMID 23684894 DOI: 10.1016/j.bmcl.2013.04.083  1
2013 Ulu A, Harris TR, Morisseau C, Miyabe C, Inoue H, Schuster G, Dong H, Iosif AM, Liu JY, Weiss RH, Chiamvimonvat N, Imig JD, Hammock BD. Anti-inflammatory effects of ω-3 polyunsaturated fatty acids and soluble epoxide hydrolase inhibitors in angiotensin-II-dependent hypertension. Journal of Cardiovascular Pharmacology. 62: 285-97. PMID 23676336 DOI: 10.1097/FJC.0b013e318298e460  1
2013 de Medina P, Paillasse MR, Segala G, Voisin M, Mhamdi L, Dalenc F, Lacroix-Triki M, Filleron T, Pont F, Saati TA, Morisseau C, Hammock BD, Silvente-Poirot S, Poirot M. Dendrogenin A arises from cholesterol and histamine metabolism and shows cell differentiation and anti-tumour properties. Nature Communications. 4: 1840. PMID 23673625 DOI: 10.1038/ncomms2835  1
2013 Poli G, Corda E, Martino PA, Dall'ara P, Bareggi SR, Bondiolotti G, Iulini B, Mazza M, Casalone C, Hwang SH, Hammock BD, Inceoglu B. Therapeutic activity of inhibition of the soluble epoxide hydrolase in a mouse model of scrapie. Life Sciences. 92: 1145-50. PMID 23651659 DOI: 10.1016/j.lfs.2013.04.014  1
2013 Bettaieb A, Nagata N, AbouBechara D, Chahed S, Morisseau C, Hammock BD, Haj FG. Soluble epoxide hydrolase deficiency or inhibition attenuates diet-induced endoplasmic reticulum stress in liver and adipose tissue. The Journal of Biological Chemistry. 288: 14189-99. PMID 23576437 DOI: 10.1074/jbc.M113.458414  1
2013 Zhang G, Panigrahy D, Mahakian LM, Yang J, Liu JY, Stephen Lee KS, Wettersten HI, Ulu A, Hu X, Tam S, Hwang SH, Ingham ES, Kieran MW, Weiss RH, Ferrara KW, ... Hammock BD, et al. Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis. Proceedings of the National Academy of Sciences of the United States of America. 110: 6530-5. PMID 23553837 DOI: 10.1073/pnas.1304321110  1
2013 Sirish P, Li N, Liu JY, Lee KS, Hwang SH, Qiu H, Zhao C, Ma SM, López JE, Hammock BD, Chiamvimonvat N. Unique mechanistic insights into the beneficial effects of soluble epoxide hydrolase inhibitors in the prevention of cardiac fibrosis. Proceedings of the National Academy of Sciences of the United States of America. 110: 5618-23. PMID 23493561 DOI: 10.1073/pnas.1221972110  1
2013 Guedes AG, Morisseau C, Sole A, Soares JH, Ulu A, Dong H, Hammock BD. Use of a soluble epoxide hydrolase inhibitor as an adjunctive analgesic in a horse with laminitis. Veterinary Anaesthesia and Analgesia. 40: 440-8. PMID 23463912 DOI: 10.1111/vaa.12030  1
2013 Stewart DN, Lango J, Nambiar KP, Falso MJ, FitzGerald PG, Rocke DM, Hammock BD, Buchholz BA. Carbon turnover in the water-soluble protein of the adult human lens. Molecular Vision. 19: 463-75. PMID 23441119  1
2013 Han JH, Kim HJ, Sudheendra L, Gee SJ, Hammock BD, Kennedy IM. Photonic crystal lab-on-a-chip for detecting staphylococcal enterotoxin B at low attomolar concentration. Analytical Chemistry. 85: 3104-9. PMID 23418954 DOI: 10.1021/ac303016h  1
2013 Hwang SH, Wecksler AT, Wagner K, Hammock BD. Rationally designed multitarget agents against inflammation and pain. Current Medicinal Chemistry. 20: 1783-99. PMID 23410172 DOI: 10.2174/0929867311320130013  1
2013 Wang Y, Wang H, Li P, Zhang Q, Kim HJ, Gee SJ, Hammock BD. Phage-displayed peptide that mimics aflatoxins and its application in immunoassay. Journal of Agricultural and Food Chemistry. 61: 2426-33. PMID 23394544 DOI: 10.1021/jf4004048  1
2013 Honetschlägerová Z, Kitada K, Husková Z, Sporková A, Kopkan L, Bürgelová M, Varcabová Š, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Kramer HJ, Kujal P, Vernerová Z, ?ervenka L. Antihypertensive and renoprotective actions of soluble epoxide hydrolase inhibition in ANG II-dependent malignant hypertension are abolished by pretreatment with L-NAME. Journal of Hypertension. 31: 321-32. PMID 23307303 DOI: 10.1097/HJH.0b013e32835b50aa  1
2013 Wettersten HI, Hee Hwang S, Li C, Shiu EY, Wecksler AT, Hammock BD, Weiss RH. A novel p21 attenuator which is structurally related to sorafenib. Cancer Biology & Therapy. 14: 278-85. PMID 23298903 DOI: 10.4161/cbt.23374  1
2013 Liu JY, Lin YP, Qiu H, Morisseau C, Rose TE, Hwang SH, Chiamvimonvat N, Hammock BD. Substituted phenyl groups improve the pharmacokinetic profile and anti-inflammatory effect of urea-based soluble epoxide hydrolase inhibitors in murine models. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 48: 619-27. PMID 23291046 DOI: 10.1016/j.ejps.2012.12.013  1
2013 Kamita SG, Yamamoto K, Dadala MM, Pha K, Morisseau C, Escaich A, Hammock BD. Cloning and characterization of a microsomal epoxide hydrolase from Heliothis virescens Insect Biochemistry and Molecular Biology. 43: 219-228. PMID 23276675 DOI: 10.1016/j.ibmb.2012.12.002  1
2013 Wagner K, Inceoglu B, Dong H, Yang J, Hwang SH, Jones P, Morisseau C, Hammock BD. Comparative efficacy of 3 soluble epoxide hydrolase inhibitors in rat neuropathic and inflammatory pain models. European Journal of Pharmacology. 700: 93-101. PMID 23276668 DOI: 10.1016/j.ejphar.2012.12.015  1
2013 Chen L, Fan C, Zhang Y, Bakri M, Dong H, Morisseau C, Maddipati KR, Luo P, Wang CY, Hammock BD, Wang MH. Beneficial effects of inhibition of soluble epoxide hydrolase on glucose homeostasis and islet damage in a streptozotocin-induced diabetic mouse model. Prostaglandins & Other Lipid Mediators. 104: 42-8. PMID 23247129 DOI: 10.1016/j.prostaglandins.2012.12.001  1
2013 Pecic S, Pakhomova S, Newcomer ME, Morisseau C, Hammock BD, Zhu Z, Rinderspacher A, Deng SX. Synthesis and structure-activity relationship of piperidine-derived non-urea soluble epoxide hydrolase inhibitors Bioorganic and Medicinal Chemistry Letters. 23: 417-421. PMID 23237835 DOI: 10.1016/j.bmcl.2012.11.084  1
2013 Lee KSS, Morisseau C, Yang J, Wang P, Hwang SH, Hammock BD. Förster resonance energy transfer competitive displacement assay for human soluble epoxide hydrolase Analytical Biochemistry. 434: 259-268. PMID 23219719 DOI: 10.1016/j.ab.2012.11.015  1
2013 Morisseau C, Sahdeo S, Cortopassi G, Hammock BD. Development of an HTS assay for EPHX2 phosphatase activity and screening of nontargeted libraries Analytical Biochemistry. 434: 105-111. PMID 23219563 DOI: 10.1016/j.ab.2012.11.017  1
2013 Vanrell L, Gonzalez-Techera A, Hammock BD, Gonzalez-Sapienza G. Nanopeptamers for the development of small-analyte lateral flow tests with a positive readout Analytical Chemistry. 85: 1177-1182. PMID 23214940 DOI: 10.1021/ac3031114  1
2013 Althurwi HN, Tse MM, Abdelhamid G, Zordoky BN, Hammock BD, El-Kadi AO. Soluble epoxide hydrolase inhibitor, TUPS, protects against isoprenaline-induced cardiac hypertrophy. British Journal of Pharmacology. 168: 1794-807. PMID 23176298 DOI: 10.1111/bph.12066  1
2013 Kundu S, Roome T, Bhattacharjee A, Carnevale KA, Yakubenko VP, Zhang R, Hwang SH, Hammock BD, Cathcart MK. Metabolic products of soluble epoxide hydrolase are essential for monocyte chemotaxis to MCP-1 in vitro and in vivo. Journal of Lipid Research. 54: 436-47. PMID 23160182 DOI: 10.1194/jlr.M031914  1
2013 Wang Q, Pang W, Cui Z, Shi J, Liu Y, Liu B, Zhou Y, Guan Y, Hammock BD, Wang Y, Zhu Y. Upregulation of soluble epoxide hydrolase in proximal tubular cells mediated proteinuria-induced renal damage. American Journal of Physiology. Renal Physiology. 304: F168-76. PMID 23152298 DOI: 10.1152/ajprenal.00129.2012  1
2013 Varcabova S, Huskova Z, Kramer HJ, Hwang SH, Hammock BD, Imig JD, Kitada K, Cervenka L. Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system. Clinical and Experimental Pharmacology & Physiology. 40: 273-81. PMID 23039246 DOI: 10.1111/1440-1681.12018  1
2013 Han JH, Kim HJ, Sudheendra L, Hass EA, Gee SJ, Hammock BD, Kennedy IM. Electrophoretic build-up of multi nanoparticle array for a highly sensitive immunoassay. Biosensors & Bioelectronics. 41: 302-8. PMID 23021853 DOI: 10.1016/j.bios.2012.08.042  1
2013 Morisseau C, Hammock BD. Impact of soluble epoxide hydrolase and epoxyeicosanoids on human health Annual Review of Pharmacology and Toxicology. 53: 37-58. PMID 23020295 DOI: 10.1146/annurev-pharmtox-011112-140244  1
2013 Xu DY, Davis BB, Wang ZH, Zhao SP, Wasti B, Liu ZL, Li N, Morisseau C, Chiamvimonvat N, Hammock BD. A potent soluble epoxide hydrolase inhibitor, t-AUCB, acts through PPARγ to modulate the function of endothelial progenitor cells from patients with acute myocardial infarction International Journal of Cardiology. 167: 1298-1304. PMID 22525341 DOI: 10.1016/j.ijcard.2012.03.167  1
2013 Zhang W, Liao J, Li H, Dong H, Bai H, Yang A, Hammock BD, Yang GY. Reduction of inflammatory bowel disease-induced tumor development in IL-10 knockout mice with soluble epoxide hydrolase gene deficiency Molecular Carcinogenesis. 52: 726-738. PMID 22517541 DOI: 10.1002/mc.21918  1
2013 Lee EH, Kim YA, Lee YT, Hammock BD, Lee HS. Competitive immunochromatographic assay for the detection of the organophosphorus pesticide EPN Food and Agricultural Immunology. 24: 129-138. DOI: 10.1080/09540105.2012.661703  1
2013 Falck D, Schebb NH, Prihatiningtyas S, Zhang J, Heus F, Morisseau C, Kool J, Hammock BD, Niessen WMA. Development of on-line liquid chromatography-biochemical detection for soluble epoxide hydrolase inhibitors in mixtures Chromatographia. 76: 13-21. DOI: 10.1007/s10337-012-2343-0  1
2012 Zivkovic AM, Yang J, Georgi K, Hegedus C, Nording ML, O'Sullivan A, German JB, Hogg RJ, Weiss RH, Bay C, Hammock BD. Serum oxylipin profiles in IgA nephropathy patients reflect kidney functional alterations. Metabolomics : Official Journal of the Metabolomic Society. 8: 1102-1113. PMID 23833568 DOI: 10.1007/s11306-012-0417-5  1
2012 Thiphom S, Prapamontol T, Chantara S, Mangklabruks A, Suphavilai C, Ahn KC, Gee SJ, Hammock BD. An enzyme-linked immunosorbent assay for detecting 3-phenoxybenzoic acid in plasma and its application in farmers and consumers. Analytical Methods : Advancing Methods and Applications. 4: 3772-3778. PMID 23667388 DOI: 10.1039/C2AY25642H  1
2012 Imig JD, Walsh KA, Hye Khan MA, Nagasawa T, Cherian-Shaw M, Shaw SM, Hammock BD. Soluble epoxide hydrolase inhibition and peroxisome proliferator activated receptor γ agonist improve vascular function and decrease renal injury in hypertensive obese rats. Experimental Biology and Medicine (Maywood, N.J.). 237: 1402-12. PMID 23354399 DOI: 10.1258/ebm.2012.012225  1
2012 Lee JY, Kim YA, Kim MY, Lee YT, Hammock BD, Lee HS. Importance of membrane selection in the development of immunochromatographic assays for low-molecular weight compounds. Analytica Chimica Acta. 757: 69-74. PMID 23206398 DOI: 10.1016/j.aca.2012.10.052  1
2012 Tamang DL, Pirzai W, Priebe GP, Traficante DC, Pier GB, Falck JR, Morisseau C, Hammock BD, McCormick BA, Gronert K, Hurley BP. Hepoxilin A(3) facilitates neutrophilic breach of lipoxygenase-expressing airway epithelial barriers. Journal of Immunology (Baltimore, Md. : 1950). 189: 4960-9. PMID 23045615 DOI: 10.4049/jimmunol.1201922  1
2012 Huang H, Yao H, Liu JY, Samra AI, Kamita SG, Cornel AJ, Hammock BD. Development of pyrethroid-like fluorescent substrates for glutathione S-transferase Analytical Biochemistry. 431: 77-83. PMID 23000005 DOI: 10.1016/j.ab.2012.09.011  1
2012 Han JH, Sudheendra L, Kim HJ, Gee SJ, Hammock BD, Kennedy IM. Ultrasensitive on-chip immunoassays with a nanoparticle-assembled photonic crystal. Acs Nano. 6: 8570-82. PMID 22957818 DOI: 10.1021/nn301656c  1
2012 Kopkan L, Husková Z, Sporková A, Varcabová Š, Honetschlägerová Z, Hwang SH, Tsai HJ, Hammock BD, Imig JD, Kramer HJ, Bürgelová M, Vojtíšková A, Kujal P, Vernerová Z, Červenka L. Soluble epoxide hydrolase inhibition exhibits antihypertensive actions independently of nitric oxide in mice with renovascular hypertension. Kidney & Blood Pressure Research. 35: 595-607. PMID 22948718 DOI: 10.1159/000339883  1
2012 Kim IH, Nishi K, Kasagami T, Morisseau C, Liu JY, Tsai HJ, Hammock BD. Biologically active ester derivatives as potent inhibitors of the soluble epoxide hydrolase. Bioorganic & Medicinal Chemistry Letters. 22: 5889-92. PMID 22901393 DOI: 10.1016/j.bmcl.2012.07.074  1
2012 Cherednichenko G, Zhang R, Bannister RA, Timofeyev V, Li N, Fritsch EB, Feng W, Barrientos GC, Schebb NH, Hammock BD, Beam KG, Chiamvimonvat N, Pessah IN. Triclosan impairs excitation-contraction coupling and Ca2+ dynamics in striated muscle. Proceedings of the National Academy of Sciences of the United States of America. 109: 14158-63. PMID 22891308 DOI: 10.1073/pnas.1211314109  1
2012 Cao Z, Hammock BD, McCoy M, Rogawski MA, Lein PJ, Pessah IN. Tetramethylenedisulfotetramine alters Ca²⁺ dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation. Toxicological Sciences : An Official Journal of the Society of Toxicology. 130: 362-72. PMID 22889812 DOI: 10.1093/toxsci/kfs244  1
2012 Guglielmino K, Jackson K, Harris TR, Vu V, Dong H, Dutrow G, Evans JE, Graham J, Cummings BP, Havel PJ, Chiamvimonvat N, Despa S, Hammock BD, Despa F. Pharmacological inhibition of soluble epoxide hydrolase provides cardioprotection in hyperglycemic rats. American Journal of Physiology. Heart and Circulatory Physiology. 303: H853-62. PMID 22865388 DOI: 10.1152/ajpheart.00154.2012  1
2012 Decker M, Adamska M, Cronin A, Di Giallonardo F, Burgener J, Marowsky A, Falck JR, Morisseau C, Hammock BD, Gruzdev A, Zeldin DC, Arand M. EH3 (ABHD9): the first member of a new epoxide hydrolase family with high activity for fatty acid epoxides. Journal of Lipid Research. 53: 2038-45. PMID 22798687 DOI: 10.1194/jlr.M024448  1
2012 Eiserich JP, Yang J, Morrissey BM, Hammock BD, Cross CE. Omics approaches in cystic fibrosis research: A focus on oxylipin profiling in airway secretions Annals of the New York Academy of Sciences. 1259: 1-9. PMID 22758630 DOI: 10.1111/j.1749-6632.2012.06580.x  1
2012 Inceoglu B, Wagner KM, Yang J, Bettaieb A, Schebb NH, Hwang SH, Morisseau C, Haj FG, Hammock BD. Acute augmentation of epoxygenated fatty acid levels rapidly reduces pain-related behavior in a rat model of type I diabetes. Proceedings of the National Academy of Sciences of the United States of America. 109: 11390-5. PMID 22733772 DOI: 10.1073/pnas.1208708109  1
2012 Liu Y, Dang H, Li D, Pang W, Hammock BD, Zhu Y. Inhibition of soluble epoxide hydrolase attenuates high-fat-diet-induced hepatic steatosis by reduced systemic inflammatory status in mice Plos One. 7. PMID 22720061 DOI: 10.1371/journal.pone.0039165  1
2012 Schebb NH, Buchholz BA, Hammock BD, Rice RH. Metabolism of the antibacterial triclocarban by human epidermal keratinocytes to yield protein adducts. Journal of Biochemical and Molecular Toxicology. 26: 230-4. PMID 22711420 DOI: 10.1002/jbt.21411  1
2012 Qiu H, Liu JY, Wei D, Li N, Yamoah EN, Hammock BD, Chiamvimonvat N. Cardiac-generated prostanoids mediate cardiac myocyte apoptosis after myocardial ischaemia. Cardiovascular Research. 95: 336-45. PMID 22707158 DOI: 10.1093/cvr/cvs191  1
2012 Frömel T, Jungblut B, Hu J, Trouvain C, Barbosa-Sicard E, Popp R, Liebner S, Dimmeler S, Hammock BD, Fleming I. Soluble epoxide hydrolase regulates hematopoietic progenitor cell function via generation of fatty acid diols. Proceedings of the National Academy of Sciences of the United States of America. 109: 9995-10000. PMID 22665795 DOI: 10.1073/pnas.1206493109  1
2012 Lin Y, Ubels JL, Schotanus MP, Yin Z, Pintea V, Hammock BD, Watsky MA. Enhancement of vitamin D metabolites in the eye following vitamin D3 supplementation and UV-B irradiation Current Eye Research. 37: 871-878. PMID 22632164 DOI: 10.3109/02713683.2012.688235  1
2012 Stephensen CB, Zerofsky M, Burnett DJ, Lin YP, Hammock BD, Hall LM, McHugh T. Ergocalciferol from mushrooms or supplements consumed with a standard meal increases 25-hydroxyergocalciferol but decreases 25-hydroxycholecalciferol in the serum of healthy adults. The Journal of Nutrition. 142: 1246-52. PMID 22623385 DOI: 10.3945/jn.112.159764  1
2012 Sanders WG, Morisseau C, Hammock BD, Cheung AK, Terry CM. Soluble epoxide hydrolase expression in a porcine model of arteriovenous graft stenosis and anti-inflammatory effects of a soluble epoxide hydrolase inhibitor. American Journal of Physiology. Cell Physiology. 303: C278-90. PMID 22621785 DOI: 10.1152/ajpcell.00386.2011  1
2012 Zhang W, Yang AL, Liao J, Li H, Dong H, Chung YT, Bai H, Matkowskyj KA, Hammock BD, Yang GY. Soluble epoxide hydrolase gene deficiency or inhibition attenuates chronic active inflammatory bowel disease in IL-10(-/-) mice. Digestive Diseases and Sciences. 57: 2580-91. PMID 22588244 DOI: 10.1007/s10620-012-2217-1  1
2012 Yang J, Eiserich JP, Cross CE, Morrissey BM, Hammock BD. Metabolomic profiling of regulatory lipid mediators in sputum from adult cystic fibrosis patients Free Radical Biology and Medicine. 53: 160-171. PMID 22580336 DOI: 10.1016/j.freeradbiomed.2012.05.001  1
2012 Inceoglu AB, Clifton HL, Yang J, Hegedus C, Hammock BD, Schaefer S. Inhibition of soluble epoxide hydrolase limits niacin-induced vasodilation in mice. Journal of Cardiovascular Pharmacology. 60: 70-5. PMID 22526297 DOI: 10.1097/FJC.0b013e3182580a5d  1
2012 McCoy MR, Yang Z, Fu X, Ahn KC, Gee SJ, Bom DC, Zhong P, Chang D, Hammock BD. Monitoring of total type ii pyrethroid pesticides in citrus oils and water by converting to a common product 3-phenoxybenzoic acid. Journal of Agricultural and Food Chemistry. 60: 5065-70. PMID 22486225 DOI: 10.1021/jf2051653  1
2012 Lundström SL, Yang J, Källberg HJ, Thunberg S, Gafvelin G, Haeggström JZ, Grönneberg R, Grunewald J, van Hage M, Hammock BD, Eklund A, Wheelock ÅM, Wheelock CE. Allergic asthmatics show divergent lipid mediator profiles from healthy controls both at baseline and following birch pollen provocation. Plos One. 7: e33780. PMID 22438998 DOI: 10.1371/journal.pone.0033780  1
2012 Morisseau C, Schebb NH, Dong H, Ulu A, Aronov PA, Hammock BD. Role of soluble epoxide hydrolase phosphatase activity in the metabolism of lysophosphatidic acids. Biochemical and Biophysical Research Communications. 419: 796-800. PMID 22387545 DOI: 10.1016/j.bbrc.2012.02.108  1
2012 Zhang D, Xie X, Chen Y, Hammock BD, Kong W, Zhu Y. Homocysteine upregulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo Circulation Research. 110: 808-817. PMID 22354938 DOI: 10.1161/CIRCRESAHA.111.259325  1
2012 Zolkowska D, Banks CN, Dhir A, Inceoglu B, Sanborn JR, McCoy MR, Bruun DA, Hammock BD, Lein PJ, Rogawski MA. Characterization of seizures induced by acute and repeated exposure to tetramethylenedisulfotetramine. The Journal of Pharmacology and Experimental Therapeutics. 341: 435-46. PMID 22328574 DOI: 10.1124/jpet.111.190579  1
2012 Neckár J, Kopkan L, Husková Z, Kolář F, Papoušek F, Kramer HJ, Hwang SH, Hammock BD, Imig JD, Malý J, Netuka I, Ošťádal B, Červenka L. Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-I-ylureido)cyclohexyloxy] benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension Clinical Science. 122: 513-525. PMID 22324471 DOI: 10.1042/CS20110622  1
2012 Duan H, Yoshimura K, Kobayashi N, Sugiyama K, Sawada J, Saito Y, Morisseau C, Hammock BD, Akatsuka T. Development of monoclonal antibodies to human microsomal epoxide hydrolase and analysis of "preneoplastic antigen"-like molecules. Toxicology and Applied Pharmacology. 260: 17-26. PMID 22310175 DOI: 10.1016/j.taap.2012.01.023  1
2012 Duan H, Takagi A, Kayano H, Koyama I, Morisseau C, Hammock BD, Akatsuka T. Monoclonal antibodies reveal multiple forms of expression of human microsomal epoxide hydrolase Toxicology and Applied Pharmacology. 260: 27-34. PMID 22306621 DOI: 10.1016/j.taap.2012.01.021  1
2012 Samra AI, Kamita SG, Yao HW, Cornel AJ, Hammock BD. Cloning and characterization of two glutathione S-transferases from pyrethroid-resistant Culex pipiens Pest Management Science. 68: 764-772. PMID 22290868 DOI: 10.1002/ps.2324  1
2012 Schebb NH, Ahn KC, Dong H, Gee SJ, Hammock BD. Whole blood is the sample matrix of choice for monitoring systemic triclocarban levels. Chemosphere. 87: 825-7. PMID 22273184 DOI: 10.1016/j.chemosphere.2011.12.077  1
2012 Villalon Landeros R, Morisseau C, Yoo HJ, Fu SH, Hammock BD, Trainor BC. Corncob bedding alters the effects of estrogens on aggressive behavior and reduces estrogen receptor-α expression in the brain. Endocrinology. 153: 949-53. PMID 22186416 DOI: 10.1210/en.2011-1745  1
2012 Panigrahy D, Edin ML, Lee CR, Huang S, Bielenberg DR, Butterfield CE, Barnés CM, Mammoto A, Mammoto T, Luria A, Benny O, Chaponis DM, Dudley AC, Greene ER, Vergilio JA, ... ... Hammock BD, et al. Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. The Journal of Clinical Investigation. 122: 178-91. PMID 22182838 DOI: 10.1172/JCI58128  1
2012 Wang L, Yang J, Guo L, Uyeminami D, Dong H, Hammock BD, Pinkerton KE. Use of a soluble epoxide hydrolase inhibitor in smoke-induced chronic obstructive pulmonary disease American Journal of Respiratory Cell and Molecular Biology. 46: 614-622. PMID 22180869 DOI: 10.1165/rcmb.2011-0359OC  1
2012 Shen HC, Hammock BD. Discovery of inhibitors of soluble epoxide hydrolase: a target with multiple potential therapeutic indications. Journal of Medicinal Chemistry. 55: 1789-808. PMID 22168898 DOI: 10.1021/jm201468j  1
2012 Kim HJ, McCoy MR, Majkova Z, Dechant JE, Gee SJ, Tabares-da Rosa S, González-Sapienza GG, Hammock BD. Isolation of alpaca anti-hapten heavy chain single domain antibodies for development of sensitive immunoassay. Analytical Chemistry. 84: 1165-71. PMID 22148739 DOI: 10.1021/ac2030255  1
2012 Pecic S, Deng SX, Morisseau C, Hammock BD, Landry DW. Design, synthesis and evaluation of non-urea inhibitors of soluble epoxide hydrolase Bioorganic and Medicinal Chemistry Letters. 22: 601-605. PMID 22079754 DOI: 10.1016/j.bmcl.2011.10.074  1
2012 Ahn KC, Kasagami T, Tsai HJ, Schebb NH, Ogunyoku T, Gee SJ, Young TM, Hammock BD. An immunoassay to evaluate human/environmental exposure to the antimicrobial triclocarban. Environmental Science & Technology. 46: 374-81. PMID 22077920 DOI: 10.1021/es202494d  1
2012 Hou HH, Hammock BD, Su KH, Morisseau C, Kou YR, Imaoka S, Oguro A, Shyue SK, Zhao JF, Lee TS. N-terminal domain of soluble epoxide hydrolase negatively regulates the VEGF-mediated activation of endothelial nitric oxide synthase. Cardiovascular Research. 93: 120-9. PMID 22072631 DOI: 10.1093/cvr/cvr267  1
2012 Iyer A, Kauter K, Alam MA, Hwang SH, Morisseau C, Hammock BD, Brown L. Pharmacological inhibition of soluble epoxide hydrolase ameliorates diet-induced metabolic syndrome in rats. Experimental Diabetes Research. 2012: 758614. PMID 22007192 DOI: 10.1155/2012/758614  1
2012 Schebb NH, Franze B, Maul R, Ranganathan A, Hammock BD. In vitro glucuronidation of the antibacterial triclocarban and its oxidative metabolites Drug Metabolism and Disposition. 40: 25-31. PMID 21953915 DOI: 10.1124/dmd.111.042283  1
2012 Ulu A, Appt S, Morisseau C, Hwang SH, Jones PD, Rose TE, Dong H, Lango J, Yang J, Tsai HJ, Miyabe C, Fortenbach C, Adams MR, Hammock BD. Pharmacokinetics and in vivo potency of soluble epoxide hydrolase inhibitors in cynomolgus monkeys. British Journal of Pharmacology. 165: 1401-12. PMID 21880036 DOI: 10.1111/j.1476-5381.2011.01641.x  1
2012 Insawang T, Selmi C, Cha'on U, Pethlert S, Yongvanit P, Areejitranusorn P, Boonsiri P, Khampitak T, Tangrassameeprasert R, Pinitsoontorn C, Prasongwattana V, Gershwin ME, Hammock BD. Monosodium glutamate (MSG) intake is associated with the prevalence of metabolic syndrome in a rural Thai population Nutrition and Metabolism. 9. DOI: 10.1186/1743-7075-9-50  1
2012 Cherednichenko G, Zhang R, Bannister RA, Timofeyev V, Li N, Fritsch EB, Feng W, Barrientos GC, Schebb NH, Hammock BD, Beam KG, Chiamvimonvat N, Pessah IN. Triclosan impairs excitation-contraction coupling and Ca2+ dynamics in striated muscle (Proceedings of the National Academy of Sciences of the United States of America (2012) 109, 35, (14158 -14163) DOI:10.1073/pnas. 1211314109) Proceedings of the National Academy of Sciences of the United States of America. 109: 16393. DOI: 10.1073/pnas.1215071109  1
2012 Huang SX, Cao B, Morisseau C, Jin Y, Hammock BD, Long YQ. Structure-based optimization of the piperazino-containing 1,3 -disubstituted ureas affording sub-nanomolar inhibitors of soluble epoxide hydrolase Medchemcomm. 3: 379-384. DOI: 10.1039/c2md00288d  1
2011 Kamita SG, Samra AI, Liu JY, Cornel AJ, Hammock BD. Juvenile hormone (JH) esterase of the mosquito Culex quinquefasciatus is not a target of the JH analog insecticide methoprene Plos One. 6. PMID 22174797 DOI: 10.1371/journal.pone.0028392  1
2011 Lundström SL, Levänen B, Nording M, Klepczynska-Nyström A, Sköld M, Haeggström JZ, Grunewald J, Svartengren M, Hammock BD, Larsson BM, Eklund A, Wheelock ÅM, Wheelock CE. Asthmatics exhibit altered oxylipin profiles compared to healthy individuals after subway air exposure. Plos One. 6: e23864. PMID 21897859 DOI: 10.1371/journal.pone.0023864  1
2011 Inoue H, Hwang SH, Wecksler AT, Hammock BD, Weiss RH. Sorafenib attenuates p21 in kidney cancer cells and augments cell death in combination with DNA-damaging chemotherapy. Cancer Biology & Therapy. 12: 827-36. PMID 21878748 DOI: 10.4161/cbt.12.9.17680  1
2011 Wagner K, Inceoglu B, Hammock BD. Soluble epoxide hydrolase inhibition, epoxygenated fatty acids and nociception Prostaglandins and Other Lipid Mediators. 96: 76-83. PMID 21854866 DOI: 10.1016/j.prostaglandins.2011.08.001  1
2011 Liu JY, Qiu H, Morisseau C, Hwang SH, Tsai HJ, Ulu A, Chiamvimonvat N, Hammock BD. Inhibition of soluble epoxide hydrolase contributes to the anti-inflammatory effect of antimicrobial triclocarban in a murine model. Toxicology and Applied Pharmacology. 255: 200-6. PMID 21741984 DOI: 10.1016/j.taap.2011.06.017  1
2011 Luria A, Bettaieb A, Xi Y, Shieh GJ, Liu HC, Inoue H, Tsai HJ, Imig JD, Haj FG, Hammock BD. Soluble epoxide hydrolase deficiency alters pancreatic islet size and improves glucose homeostasis in a model of insulin resistance. Proceedings of the National Academy of Sciences of the United States of America. 108: 9038-43. PMID 21571638 DOI: 10.1073/pnas.1103482108  1
2011 Hwang SH, Wagner KM, Morisseau C, Liu JY, Dong H, Wecksler AT, Hammock BD. Synthesis and structure-activity relationship studies of urea-containing pyrazoles as dual inhibitors of cyclooxygenase-2 and soluble epoxide hydrolase. Journal of Medicinal Chemistry. 54: 3037-50. PMID 21434686 DOI: 10.1021/jm2001376  1
2011 Inceoglu B, Wagner K, Schebb NH, Morisseau C, Jinks SL, Ulu A, Hegedus C, Rose T, Brosnan R, Hammock BD. Analgesia mediated by soluble epoxide hydrolase inhibitors is dependent on cAMP. Proceedings of the National Academy of Sciences of the United States of America. 108: 5093-7. PMID 21383170 DOI: 10.1073/pnas.1101073108  1
2011 Koeners MP, Wesseling S, Ulu A, Sepúlveda RL, Morisseau C, Braam B, Hammock BD, Joles JA. Soluble epoxide hydrolase in the generation and maintenance of high blood pressure in spontaneously hypertensive rats. American Journal of Physiology. Endocrinology and Metabolism. 300: E691-8. PMID 21266668 DOI: 10.1152/ajpendo.00710.2010  1
2011 Honetschlägerová Z, Z Husková Z, Vaňourková Z, Sporková A, Kramer HJ, Hwang SH, Tsai HJ, Hammock BD, Imig JD, Červenka L, Kopkan L. Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension. The Journal of Physiology. 589: 207-19. PMID 21078594 DOI: 10.1113/jphysiol.2010.199505  1
2010 Morisseau C, Inceoglu B, Schmelzer K, Tsai HJ, Jinks SL, Hegedus CM, Hammock BD. Naturally occurring monoepoxides of eicosapentaenoic acid and docosahexaenoic acid are bioactive antihyperalgesic lipids. Journal of Lipid Research. 51: 3481-90. PMID 20664072 DOI: 10.1194/jlr.M006007  1
2010 Tsai HJ, Hwang SH, Morisseau C, Yang J, Jones PD, Kasagami T, Kim IH, Hammock BD. Pharmacokinetic screening of soluble epoxide hydrolase inhibitors in dogs. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 40: 222-38. PMID 20359531 DOI: 10.1016/j.ejps.2010.03.018  1
2010 Simpkins AN, Rudic RD, Roy S, Tsai HJ, Hammock BD, Imig JD. Soluble epoxide hydrolase inhibition modulates vascular remodeling. American Journal of Physiology. Heart and Circulatory Physiology. 298: H795-806. PMID 20035028 DOI: 10.1152/ajpheart.00543.2009  1
2010 Liu JY, Yang J, Inceoglu B, Qiu H, Ulu A, Hwang SH, Chiamvimonvat N, Hammock BD. Inhibition of soluble epoxide hydrolase enhances the anti-inflammatory effects of aspirin and 5-lipoxygenase activation protein inhibitor in a murine model. Biochemical Pharmacology. 79: 880-7. PMID 19896470 DOI: 10.1016/j.bcp.2009.10.025  1
2009 Ahn KC, Gee SJ, Tsai HJ, Bennett D, Nishioka MG, Blum A, Fishman E, Hammock BD. Immunoassay for monitoring environmental and human exposure to the polybrominated diphenyl ether BDE-47. Environmental Science & Technology. 43: 7784-90. PMID 19921894 DOI: 10.1021/es9009037  1
2009 Luria A, Morisseau C, Tsai HJ, Yang J, Inceoglu B, De Taeye B, Watkins SM, Wiest MM, German JB, Hammock BD. Alteration in plasma testosterone levels in male mice lacking soluble epoxide hydrolase. American Journal of Physiology. Endocrinology and Metabolism. 297: E375-83. PMID 19458064 DOI: 10.1152/ajpendo.00131.2009  1
2009 Simpkins AN, Rudic RD, Schreihofer DA, Roy S, Manhiani M, Tsai HJ, Hammock BD, Imig JD. Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection. The American Journal of Pathology. 174: 2086-95. PMID 19435785 DOI: 10.2353/ajpath.2009.080544  1
2009 Kasagami T, Kim IH, Tsai HJ, Nishi K, Hammock BD, Morisseau C. Salicylate-urea-based soluble epoxide hydrolase inhibitors with high metabolic and chemical stabilities. Bioorganic & Medicinal Chemistry Letters. 19: 1784-9. PMID 19216074 DOI: 10.1016/j.bmcl.2009.01.069  1
2009 Inceoglu AB, Waite TD, Christiansen JA, McAbee RD, Kamita SG, Hammock BD, Cornel AJ. A rapid luminescent assay for measuring cytochrome P450 activity in individual larval Culex pipiens complex mosquitoes (Diptera: Culicidae). Journal of Medical Entomology. 46: 83-92. PMID 19198521 DOI: 10.1603/033.046.0111  1
2009 Liu JY, Tsai HJ, Hwang SH, Jones PD, Morisseau C, Hammock BD. Pharmacokinetic optimization of four soluble epoxide hydrolase inhibitors for use in a murine model of inflammation. British Journal of Pharmacology. 156: 284-96. PMID 19154430 DOI: 10.1111/j.1476-5381.2008.00009.x  1
2009 Olearczyk JJ, Quigley JE, Mitchell BC, Yamamoto T, Kim IH, Newman JW, Luria A, Hammock BD, Imig JD. Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats. Clinical Science (London, England : 1979). 116: 61-70. PMID 18459944 DOI: 10.1042/CS20080039  1
2008 Inceoglu B, Jinks SL, Ulu A, Hegedus CM, Georgi K, Schmelzer KR, Wagner K, Jones PD, Morisseau C, Hammock BD. Soluble epoxide hydrolase and epoxyeicosatrienoic acids modulate two distinct analgesic pathways. Proceedings of the National Academy of Sciences of the United States of America. 105: 18901-6. PMID 19028872 DOI: 10.1073/pnas.0809765105  1
2008 EnayetAllah AE, Luria A, Luo B, Tsai HJ, Sura P, Hammock BD, Grant DF. Opposite regulation of cholesterol levels by the phosphatase and hydrolase domains of soluble epoxide hydrolase. The Journal of Biological Chemistry. 283: 36592-8. PMID 18974052 DOI: 10.1074/jbc.M806315200  1
2008 Fife KL, Liu Y, Schmelzer KR, Tsai HJ, Kim IH, Morisseau C, Hammock BD, Kroetz DL. Inhibition of soluble epoxide hydrolase does not protect against endotoxin-mediated hepatic inflammation. The Journal of Pharmacology and Experimental Therapeutics. 327: 707-15. PMID 18815352 DOI: 10.1124/jpet.108.142398  1
2008 Ulu A, Davis BB, Tsai HJ, Kim IH, Morisseau C, Inceoglu B, Fiehn O, Hammock BD, Weiss RH. Soluble epoxide hydrolase inhibitors reduce the development of atherosclerosis in apolipoprotein e-knockout mouse model. Journal of Cardiovascular Pharmacology. 52: 314-23. PMID 18791465 DOI: 10.1097/FJC.0b013e318185fa3c  1
2008 Athirakul K, Bradbury JA, Graves JP, DeGraff LM, Ma J, Zhao Y, Couse JF, Quigley R, Harder DR, Zhao X, Imig JD, Pedersen TL, Newman JW, Hammock BD, Conley AJ, et al. Increased blood pressure in mice lacking cytochrome P450 2J5. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 4096-108. PMID 18716027 DOI: 10.1096/fj.08-114413  1
2008 Wheelock CE, Phillips BM, Anderson BS, Miller JL, Miller MJ, Hammock BD. Applications of carboxylesterase activity in environmental monitoring and toxicity identification evaluations (TIEs). Reviews of Environmental Contamination and Toxicology. 195: 117-78. PMID 18418956  1
2008 Morisseau C, Newman JW, Wheelock CE, Hill Iii T, Morin D, Buckpitt AR, Hammock BD. Development of metabolically stable inhibitors of Mammalian microsomal epoxide hydrolase. Chemical Research in Toxicology. 21: 951-7. PMID 18363382 DOI: 10.1021/tx700446u  1
2008 Wheelock CE, Colvin ME, Sanborn JR, Hammock BD. Substituted 3-phenylpropenoates and related analogs: electron ionization mass spectral fragmentation and density functional theory calculations. Journal of Mass Spectrometry : Jms. 43: 1053-62. PMID 18286670 DOI: 10.1002/jms.1384  1
2008 Wheelock CE, Forshed J, Goto S, Hammock BD, Newman JW. Effects of pyridine exposure upon structural lipid metabolism in Swiss Webster mice. Chemical Research in Toxicology. 21: 583-90. PMID 18251509 DOI: 10.1021/tx7002454  1
2008 Dreisbach AW, Rice JC, Japa S, Newman JW, Sigel A, Gill RS, Hess AE, Cemo AC, Fonseca JP, Hammock BD, Lertora JJL, Hamm LL. Salt loading increases urinary excretion of linoleic acid diols and triols in healthy human subjects Hypertension. 51: 755-761. PMID 18227407 DOI: 10.1161/HYPERTENSIONAHA.107.100123  1
2008 Wheelock CE, Nishi K, Ying A, Jones PD, Colvin ME, Olmstead MM, Hammock BD. Influence of sulfur oxidation state and steric bulk upon trifluoromethyl ketone (TFK) binding kinetics to carboxylesterases and fatty acid amide hydrolase (FAAH). Bioorganic & Medicinal Chemistry. 16: 2114-30. PMID 18023188 DOI: 10.1016/j.bmc.2007.10.081  1
2007 Wheelock CE, Goto S, Hammock BD, Newman JW. Clofibrate-induced changes in the liver, heart, brain and white adipose lipid metabolome of Swiss-Webster mice. Metabolomics : Official Journal of the Metabolomic Society. 3: 137-145. PMID 19079556 DOI: 10.1007/s11306-007-0052-8  1
2007 Kim IH, Tsai HJ, Nishi K, Kasagami T, Morisseau C, Hammock BD. 1,3-disubstituted ureas functionalized with ether groups are potent inhibitors of the soluble epoxide hydrolase with improved pharmacokinetic properties. Journal of Medicinal Chemistry. 50: 5217-26. PMID 17894481 DOI: 10.1021/jm070705c  1
2007 Hillard CJ, Ho WS, Thompson J, Gauthier KM, Wheelock CE, Huang H, Hammock BD. Inhibition of 2-arachidonoylglycerol catabolism modulates vasoconstriction of rat middle cerebral artery by the thromboxane mimetic, U-46619. British Journal of Pharmacology. 152: 691-8. PMID 17891162 DOI: 10.1038/sj.bjp.0707468  1
2007 Chiamvimonvat N, Ho CM, Tsai HJ, Hammock BD. The soluble epoxide hydrolase as a pharmaceutical target for hypertension. Journal of Cardiovascular Pharmacology. 50: 225-37. PMID 17878749 DOI: 10.1097/FJC.0b013e3181506445  1
2007 Hwang SH, Tsai HJ, Liu JY, Morisseau C, Hammock BD. Orally bioavailable potent soluble epoxide hydrolase inhibitors. Journal of Medicinal Chemistry. 50: 3825-40. PMID 17616115 DOI: 10.1021/jm070270t  1
2007 Newman JW, Kaysen GA, Hammock BD, Shearer GC. Proteinuria increases oxylipid concentrations in VLDL and HDL but not LDL particles in the rat. Journal of Lipid Research. 48: 1792-800. PMID 17496268 DOI: 10.1194/jlr.M700146-JLR200  0.64
2007 Endsley MP, Aggarwal N, Isbell MA, Wheelock CE, Hammock BD, Falck JR, Campbell WB, Nithipatikom K. Diverse roles of 2-arachidonoylglycerol in invasion of prostate carcinoma cells: Location, hydrolysis and 12-lipoxygenase metabolism. International Journal of Cancer. Journal International Du Cancer. 121: 984-91. PMID 17443494 DOI: 10.1002/ijc.22761  1
2007 Zhang W, Koerner IP, Noppens R, Grafe M, Tsai HJ, Morisseau C, Luria A, Hammock BD, Falck JR, Alkayed NJ. Soluble epoxide hydrolase: a novel therapeutic target in stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 27: 1931-40. PMID 17440491 DOI: 10.1038/sj.jcbfm.9600494  1
2007 Huang H, Nishi K, Tsai HJ, Hammock BD. Development of highly sensitive fluorescent assays for fatty acid amide hydrolase. Analytical Biochemistry. 363: 12-21. PMID 17291440 DOI: 10.1016/j.ab.2006.10.041  1
2007 Wadkins RM, Hyatt JL, Edwards CC, Tsurkan L, Redinbo MR, Wheelock CE, Jones PD, Hammock BD, Potter PM. Analysis of mammalian carboxylesterase inhibition by trifluoromethylketone-containing compounds. Molecular Pharmacology. 71: 713-23. PMID 17167034 DOI: 10.1124/mol.105.021683  1
2007 Luria A, Weldon SM, Kabcenell AK, Ingraham RH, Matera D, Jiang H, Gill R, Morisseau C, Newman JW, Hammock BD. Compensatory mechanism for homeostatic blood pressure regulation in Ephx2 gene-disrupted mice. The Journal of Biological Chemistry. 282: 2891-8. PMID 17135253 DOI: 10.1074/jbc.M608057200  0.64
2007 Kim IH, Nishi K, Tsai HJ, Bradford T, Koda Y, Watanabe T, Morisseau C, Blanchfield J, Toth I, Hammock BD. Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase. Bioorganic & Medicinal Chemistry. 15: 312-23. PMID 17046265 DOI: 10.1016/j.bmc.2006.09.057  1
2006 Xu D, Li N, He Y, Timofeyev V, Lu L, Tsai HJ, Kim IH, Tuteja D, Mateo RK, Singapuri A, Davis BB, Low R, Hammock BD, Chiamvimonvat N. Prevention and reversal of cardiac hypertrophy by soluble epoxide hydrolase inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 103: 18733-8. PMID 17130447 DOI: 10.1073/pnas.0609158103  1
2006 Inceoglu AB, Kamita SG, Hammock BD. Genetically modified baculoviruses: a historical overview and future outlook. Advances in Virus Research. 68: 323-60. PMID 16997016 DOI: 10.1016/S0065-3527(06)68009-3  1
2006 Morisseau C, Newman JW, Tsai HJ, Baecker PA, Hammock BD. Peptidyl-urea based inhibitors of soluble epoxide hydrolases. Bioorganic & Medicinal Chemistry Letters. 16: 5439-44. PMID 16908134 DOI: 10.1016/j.bmcl.2006.07.073  1
2006 Jones PD, Tsai HJ, Do ZN, Morisseau C, Hammock BD. Synthesis and SAR of conformationally restricted inhibitors of soluble epoxide hydrolase. Bioorganic & Medicinal Chemistry Letters. 16: 5212-6. PMID 16870439 DOI: 10.1016/j.bmcl.2006.07.009  1
2006 Seubert JM, Sinal CJ, Graves J, DeGraff LM, Bradbury JA, Lee CR, Goralski K, Carey MA, Luria A, Newman JW, Hammock BD, Falck JR, Roberts H, Rockman HA, Murphy E, et al. Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function. Circulation Research. 99: 442-50. PMID 16857962 DOI: 10.1161/01.RES.0000237390.92932.37  1
2006 Wheelock CE, Miller JL, Miller MJ, Phillips BM, Huntley SA, Gee SJ, Tjeerdema RS, Hammock BD. Use of carboxylesterase activity to remove pyrethroid-associated toxicity to Ceriodaphnia dubia and Hyalella azteca in toxicity identification evaluations. Environmental Toxicology and Chemistry / Setac. 25: 973-84. PMID 16629136 DOI: 10.1897/05-334R.1  1
2006 Lee CR, North KE, Bray MS, Fornage M, Seubert JM, Newman JW, Hammock BD, Couper DJ, Heiss G, Zeldin DC. Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study. Human Molecular Genetics. 15: 1640-9. PMID 16595607 DOI: 10.1093/hmg/ddl085  1
2006 Wogulis M, Wheelock CE, Kamita SG, Hinton AC, Whetstone PA, Hammock BD, Wilson DK. Structural studies of a potent insect maturation inhibitor bound to the juvenile hormone esterase of Manduca sexta. Biochemistry. 45: 4045-57. PMID 16566578 DOI: 10.1021/bi0521644  1
2006 Ahn KC, Ma SJ, Tsai HJ, Gee SJ, Hammock BD. An immunoassay for a urinary metabolite as a biomarker of human exposure to the pyrethroid insecticide permethrin. Analytical and Bioanalytical Chemistry. 384: 713-22. PMID 16416099 DOI: 10.1007/s00216-005-0220-5  1
2006 Davis BB, Morisseau C, Newman JW, Pedersen TL, Hammock BD, Weiss RH. Attenuation of vascular smooth muscle cell proliferation by 1-cyclohexyl-3-dodecyl urea is independent of soluble epoxide hydrolase inhibition. The Journal of Pharmacology and Experimental Therapeutics. 316: 815-21. PMID 16221742 DOI: 10.1124/jpet.105.091876  0.64
2005 Dorrance AM, Rupp N, Pollock DM, Newman JW, Hammock BD, Imig JD. An epoxide hydrolase inhibitor, 12-(3-adamantan-1-yl-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats. Journal of Cardiovascular Pharmacology. 46: 842-8. PMID 16306811  0.64
2005 Imig JD, Zhao X, Zaharis CZ, Olearczyk JJ, Pollock DM, Newman JW, Kim IH, Watanabe T, Hammock BD. An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension. Hypertension. 46: 975-81. PMID 16157792 DOI: 10.1161/01.HYP.0000176237.74820.75  0.64
2005 Tran KL, Aronov PA, Tanaka H, Newman JW, Hammock BD, Morisseau C. Lipid sulfates and sulfonates are allosteric competitive inhibitors of the N-terminal phosphatase activity of the mammalian soluble epoxide hydrolase. Biochemistry. 44: 12179-87. PMID 16142916 DOI: 10.1021/bi050842g  0.64
2005 Kang KD, Jones PD, Huang H, Zhang R, Mostovich LA, Wheelock CE, Watanabe T, Gulyaeva LF, Hammock BD. Evaluation of alpha-cyano ethers as fluorescent substrates for assay of cytochrome P450 enzyme activity. Analytical Biochemistry. 344: 183-92. PMID 16083846 DOI: 10.1016/j.ab.2005.06.032  1
2005 Wheelock CE, Eder KJ, Werner I, Huang H, Jones PD, Brammell BF, Elskus AA, Hammock BD. Individual variability in esterase activity and CYP1A levels in Chinook salmon (Oncorhynchus tshawytscha) exposed to esfenvalerate and chlorpyrifos. Aquatic Toxicology (Amsterdam, Netherlands). 74: 172-92. PMID 16011852 DOI: 10.1016/j.aquatox.2005.05.009  1
2005 Schmelzer KR, Kubala L, Newman JW, Kim IH, Eiserich JP, Hammock BD. Soluble epoxide hydrolase is a therapeutic target for acute inflammation. Proceedings of the National Academy of Sciences of the United States of America. 102: 9772-7. PMID 15994227 DOI: 10.1073/pnas.0503279102  0.64
2005 Wheelock CE, Miller JL, Miller MJ, Phillips BM, Gee SJ, Tjeerdema RS, Hammock BD. Influence of container adsorption upon observed pyrethroid toxicity to Ceriodaphnia dubia and Hyalella azteca. Aquatic Toxicology (Amsterdam, Netherlands). 74: 47-52. PMID 15951033 DOI: 10.1016/j.aquatox.2005.04.007  1
2005 Nithipatikom K, Endsley MP, Isbell MA, Wheelock CE, Hammock BD, Campbell WB. A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells. Biochemical and Biophysical Research Communications. 332: 1028-33. PMID 15919052 DOI: 10.1016/j.bbrc.2005.05.049  1
2005 Kim IH, Heirtzler FR, Morisseau C, Nishi K, Tsai HJ, Hammock BD. Optimization of amide-based inhibitors of soluble epoxide hydrolase with improved water solubility. Journal of Medicinal Chemistry. 48: 3621-9. PMID 15887969 DOI: 10.1021/jm0500929  1
2005 Shearer GC, Newman JW, Hammock BD, Kaysen GA. Graded effects of proteinuria on HDL structure in nephrotic rats. Journal of the American Society of Nephrology : Jasn. 16: 1309-19. PMID 15788471 DOI: 10.1681/ASN.2004080644  0.64
2005 Newman JW, Morisseau C, Hammock BD. Epoxide hydrolases: their roles and interactions with lipid metabolism. Progress in Lipid Research. 44: 1-51. PMID 15748653 DOI: 10.1016/j.plipres.2004.10.001  0.64
2004 Wheelock CE, Miller JL, Miller MJ, Gee SJ, Shan G, Hammock BD. Development of toxicity identification evaluation procedures for pyrethroid detection using esterase activity. Environmental Toxicology and Chemistry / Setac. 23: 2699-708. PMID 15559286 DOI: 10.1897/03-544  1
2004 Stok JE, Goloshchapov A, Song C, Wheelock CE, Derbel MB, Morisseau C, Hammock BD. Investigation of the role of a second conserved serine in carboxylesterases via site-directed mutagenesis. Archives of Biochemistry and Biophysics. 430: 247-55. PMID 15369824 DOI: 10.1016/j.abb.2004.06.020  1
2004 Dey A, Williams RS, Pollock DM, Stepp DW, Newman JW, Hammock BD, Imig JD. Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria. Obesity Research. 12: 1278-89. PMID 15340111 DOI: 10.1038/oby.2004.162  1
2004 Newman JW, Stok JE, Vidal JD, Corbin CJ, Huang Q, Hammock BD, Conley AJ. Cytochrome p450-dependent lipid metabolism in preovulatory follicles. Endocrinology. 145: 5097-105. PMID 15308618 DOI: 10.1210/en.2004-0710  1
2004 Stok JE, Huang H, Jones PD, Wheelock CE, Morisseau C, Hammock BD. Identification, expression, and purification of a pyrethroid-hydrolyzing carboxylesterase from mouse liver microsomes. The Journal of Biological Chemistry. 279: 29863-9. PMID 15123619 DOI: 10.1074/jbc.M403673200  1
2004 McAbee RD, Kang KD, Stanich MA, Christiansen JA, Wheelock CE, Inman AD, Hammock BD, Cornel AJ. Pyrethroid tolerance in Culex pipiens pipiens var molestus from Marin County, California. Pest Management Science. 60: 359-68. PMID 15119598 DOI: 10.1002/ps.799  1
2004 Zhao X, Yamamoto T, Newman JW, Kim IH, Watanabe T, Hammock BD, Stewart J, Pollock JS, Pollock DM, Imig JD. Soluble epoxide hydrolase inhibition protects the kidney from hypertension-induced damage. Journal of the American Society of Nephrology : Jasn. 15: 1244-53. PMID 15100364  0.64
2004 DuTeaux SB, Newman JW, Morisseau C, Fairbairn EA, Jelks K, Hammock BD, Miller MG. Epoxide hydrolases in the rat epididymis: possible roles in xenobiotic and endogenous fatty acid metabolism. Toxicological Sciences : An Official Journal of the Society of Toxicology. 78: 187-95. PMID 14737000 DOI: 10.1093/toxsci/kfh066  1
2003 Viswanathan S, Hammock BD, Newman JW, Meerarani P, Toborek M, Hennig B. Involvement of CYP 2C9 in mediating the proinflammatory effects of linoleic acid in vascular endothelial cells. Journal of the American College of Nutrition. 22: 502-10. PMID 14684755  0.64
2003 Taniai K, Inceoglu AB, Yukuhiro K, Hammock BD. Characterization and cDNA cloning of a clofibrate-inducible microsomal epoxide hydrolase in Drosophila melanogaster. European Journal of Biochemistry / Febs. 270: 4696-705. PMID 14622257 DOI: 10.1046/j.1432-1033.2003.03868.x  1
2003 Wheelock CE, Nakagawa Y, Akamatsu M, Hammock BD. Use of classical and 3-D QSAR to examine the hydration state of juvenile hormone esterase inhibitors. Bioorganic & Medicinal Chemistry. 11: 5101-16. PMID 14604674 DOI: 10.1016/j.bmc.2003.08.023  1
2003 Kamita SG, Hinton AC, Wheelock CE, Wogulis MD, Wilson DK, Wolf NM, Stok JE, Hock B, Hammock BD. Juvenile hormone (JH) esterase: why are you so JH specific? Insect Biochemistry and Molecular Biology. 33: 1261-73. PMID 14599498 DOI: 10.1016/j.ibmb.2003.08.004  1
2003 Watanabe T, Morisseau C, Newman JW, Hammock BD. In vitro metabolism of the mammalian soluble epoxide hydrolase inhibitor, 1-cyclohexyl-3-dodecyl-urea. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 31: 846-53. PMID 12814960 DOI: 10.1124/dmd.31.7.846  0.64
2003 Hinton AC, Hammock BD. Juvenile hormone esterase (JHE) from Tenebrio molitor: full-length cDNA sequence, in vitro expression, and characterization of the recombinant protein. Insect Biochemistry and Molecular Biology. 33: 477-87. PMID 12706627 DOI: 10.1016/S0965-1748(03)00010-9  1
2003 Wheelock CE, Wheelock AM, Zhang R, Stok JE, Morisseau C, Le Valley SE, Green CE, Hammock BD. Evaluation of alpha-cyanoesters as fluorescent substrates for examining interindividual variation in general and pyrethroid-selective esterases in human liver microsomes. Analytical Biochemistry. 315: 208-22. PMID 12689831 DOI: 10.1016/S0003-2697(03)00002-2  1
2003 Hinton AC, Hammock BD. In vitro expression and biochemical characterization of juvenile hormone esterase from Manduca sexta. Insect Biochemistry and Molecular Biology. 33: 317-29. PMID 12609517 DOI: 10.1016/S0965-1748(02)00246-1  1
2003 Newman JW, Morisseau C, Harris TR, Hammock BD. The soluble epoxide hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid phosphate phosphatase activity. Proceedings of the National Academy of Sciences of the United States of America. 100: 1558-63. PMID 12574510 DOI: 10.1073/pnas.0437724100  1
2003 Denton DL, Wheelock CE, Murray SA, Deanovic LA, Hammock BD, Hinton DE. Joint acute toxicity of esfenvalerate and diazinon to larval fathead minnows (Pimephales promelas). Environmental Toxicology and Chemistry / Setac. 22: 336-41. PMID 12558165 DOI: 10.1897/1551-5028(2003)022<0336:JATOEA>2.0.CO;2  1
2002 Wheelock CE, Colvin ME, Uemura I, Olmstead MM, Sanborn JR, Nakagawa Y, Jones AD, Hammock BD. Use of ab initio calculations to predict the biological potency of carboxylesterase inhibitors. Journal of Medicinal Chemistry. 45: 5576-93. PMID 12459025 DOI: 10.1021/jm020072w  1
2002 Inceoglu AB, Hayashida Y, Lango J, Ishida AT, Hammock BD. A single charged surface residue modifies the activity of ikitoxin, a beta-type Na+ channel toxin from Parabuthus transvaalicus. European Journal of Biochemistry / Febs. 269: 5369-76. PMID 12423335 DOI: 10.1046/j.1432-1033.2002.03171.x  1
2002 Pei Z, Reske G, Huang Q, Hammock BD, Qi Y, Chejanovsky N. Characterization of the apoptosis suppressor protein P49 from the Spodoptera littoralis nucleopolyhedrovirus. The Journal of Biological Chemistry. 277: 48677-84. PMID 12324475 DOI: 10.1074/jbc.M208810200  0.64
2002 Newman JW, Watanabe T, Hammock BD. The simultaneous quantification of cytochrome P450 dependent linoleate and arachidonate metabolites in urine by HPLC-MS/MS. Journal of Lipid Research. 43: 1563-78. PMID 12235189  0.64
2002 Morisseau C, Goodrow MH, Newman JW, Wheelock CE, Dowdy DL, Hammock BD. Structural refinement of inhibitors of urea-based soluble epoxide hydrolases. Biochemical Pharmacology. 63: 1599-608. PMID 12007563 DOI: 10.1016/S0006-2952(02)00952-8  1
2001 Wheelock CE, Severson TF, Hammock BD. Synthesis of new carboxylesterase inhibitors and evaluation of potency and water solubility. Chemical Research in Toxicology. 14: 1563-72. PMID 11743738 DOI: 10.1021/tx015508+  1
2001 Hinton AC, Hammock BD. Purification of juvenile hormone esterase and molecular cloning of the cDNA from Manduca sexta. Insect Biochemistry and Molecular Biology. 32: 57-66. PMID 11719069 DOI: 10.1016/S0965-1748(01)00079-0  1
2001 Inceoglu AB, Kamita SG, Hinton AC, Huang Q, Severson TF, Kang K, Hammock BD. Recombinant baculoviruses for insect control. Pest Management Science. 57: 981-7. PMID 11695193 DOI: 10.1002/ps.393  1
2001 Huang Q, Deveraux QL, Maeda S, Stennicke HR, Hammock BD, Reed JC. Cloning and characterization of an inhibitor of apoptosis protein (IAP) from Bombyx mori. Biochimica Et Biophysica Acta. 1499: 191-8. PMID 11341966  0.64
2001 Newman JW, Denton DL, Morisseau C, Koger CS, Wheelock CE, Hinton DE, Hammock BD. Evaluation of fish models of soluble epoxide hydrolase inhibition. Environmental Health Perspectives. 109: 61-6. PMID 11171526  1
2000 Nakagawa Y, Wheelock CE, Morisseau C, Goodrow MH, Hammock BG, Hammock BD. 3-D QSAR analysis of inhibition of murine soluble epoxide hydrolase (MsEH) by benzoylureas, arylureas, and their analogues. Bioorganic & Medicinal Chemistry. 8: 2663-73. PMID 11092551 DOI: 10.1016/S0968-0896(00)00198-X  0.36
2000 Thomas BA, Hinton AC, Moskowitz H, Severson TF, Hammock BD. Isolation of juvenile hormone esterase and its partial cDNA clone from the beetle, Tenebrio molitor. Insect Biochemistry and Molecular Biology. 30: 529-40. PMID 10844245 DOI: 10.1016/S0965-1748(00)00020-5  1
2000 Nussbaumer C, Hinton AC, Schopf A, Stradner A, Hammock BD. Isolation and characterization of juvenile hormone esterase from hemolymph of Lymantria dispar by affinity- and by anion-exchange chromatography. Insect Biochemistry and Molecular Biology. 30: 307-14. PMID 10727897 DOI: 10.1016/S0965-1748(00)00002-3  1
2000 Huang Q, Deveraux QL, Maeda S, Salvesen GS, Stennicke HR, Hammock BD, Reed JC. Evolutionary conservation of apoptosis mechanisms: lepidopteran and baculoviral inhibitor of apoptosis proteins are inhibitors of mammalian caspase-9. Proceedings of the National Academy of Sciences of the United States of America. 97: 1427-32. PMID 10677478 DOI: 10.1073/pnas.97.4.1427  1
1996 Huang TL, Shiotsuki T, Uematsu T, Borhan B, Li QX, Hammock BD. Structure-activity relationships for substrates and inhibitors of mammalian liver microsomal carboxylesterases. Pharmaceutical Research. 13: 1495-500. PMID 8899840 DOI: 10.1023/A:1016071311190  1
1996 Moghaddam M, Motoba K, Borhan B, Pinot F, Hammock BD. Novel metabolic pathways for linoleic and arachidonic acid metabolism. Biochimica Et Biophysica Acta. 1290: 327-39. PMID 8765137 DOI: 10.1016/0304-4165(96)00037-2  1
1996 Grant DF, Greene JF, Pinot F, Borhan B, Moghaddam MF, Hammock BD, McCutchen B, Ohkawa H, Luo G, Guenthner TM. Development of an in situ toxicity assay system using recombinant baculoviruses. Biochemical Pharmacology. 51: 503-15. PMID 8619897 DOI: 10.1016/0006-2952(95)02227-9  1
1995 Borhan B, Mebrahtu T, Nazarian S, Kurth MJ, Hammock BD. Improved radiolabeled substrates for soluble epoxide hydrolase. Analytical Biochemistry. 231: 188-200. PMID 8678300 DOI: 10.1006/abio.1995.1520  1
1995 Pinot F, Grant DF, Beetham JK, Parker AG, Borhan B, Landt S, Jones AD, Hammock BD. Molecular and biochemical evidence for the involvement of the Asp-333-His-523 pair in the catalytic mechanism of soluble epoxide hydrolase. The Journal of Biological Chemistry. 270: 7968-74. PMID 7713895  1
1995 Borhan B, Ko Y, Mackay C, Wilson BW, Kurth MJ, Hammock BD. Development of surrogate substrates for neuropathy target esterase. Biochimica Et Biophysica Acta. 1250: 171-82. PMID 7632722 DOI: 10.1016/0167-4838(95)00058-3  1
1995 Borhan B, Jones AD, Pinot F, Grant DF, Kurth MJ, Hammock BD. Mechanism of soluble epoxide hydrolase. Formation of an alpha-hydroxy ester-enzyme intermediate through Asp-333. The Journal of Biological Chemistry. 270: 26923-30. PMID 7592938  1
1994 Krämer PM, Li QX, Hammock BD. Integration of liquid chromatography with immunoassay: an approach combining the strengths of both methods. Journal of Aoac International. 77: 1275-87. PMID 7950427  0.8
1992 Nourooz-Zadeh J, Uematsu T, Borhan B, Kurth MJ, Hammock BD. Characterization of the cytosolic epoxide hydrolase-catalyzed hydration products from 9,10:12,13-diepoxy stearic esters. Archives of Biochemistry and Biophysics. 294: 675-85. PMID 1567223 DOI: 10.1016/0003-9861(92)90741-E  1
1989 Li QX, Gee SJ, McChesney MM, Hammock BD, Seiber JN. Comparison of an enzyme-linked immunosorbent assay and a gas chromatographic procedure for the determination of molinate residues. Analytical Chemistry. 61: 819-23. PMID 2719274  1
1974 Gill SS, Hammock BD, Casida JE. Mammalian metabolism and environmental degradation of the juvenoid 1-(4'-ethylphenoxy)-3,7-dimethyl-6,7-epoxy-trans-2-octene and related compounds. Journal of Agricultural and Food Chemistry. 22: 386-95. PMID 4840500  1
1974 Hammock LG, Hammock BD, Casida JE. Detection and analysis of epoxides with 4-(p-Nitrobenzyl)-pyridine. Bulletin of Environmental Contamination and Toxicology. 12: 759-64. PMID 4457188  1
1974 Hammock BD, Gill SS, Casida JE. Synthesis and morphogenetic activity of derivaties and analogs of aryl geranyl ether juvenoids. Journal of Agricultural and Food Chemistry. 22: 379-85. PMID 4365477  1
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