Year |
Citation |
Score |
2019 |
Dohle W, Su X, Mills SJ, Rossi AM, Taylor CW, Potter BVL. A synthetic cyclitol-nucleoside conjugate polyphosphate is a highly potent second messenger mimic. Chemical Science. 10: 5382-5390. PMID 31171961 DOI: 10.1039/C9Sc00445A |
0.309 |
|
2018 |
Nel M, Joubert AM, Dohle W, Potter BV, Theron AE. Modes of cell death induced by tetrahydroisoquinoline-based analogs in MDA-MB-231 breast and A549 lung cancer cell lines. Drug Design, Development and Therapy. 12: 1881-1904. PMID 29983544 DOI: 10.2147/Dddt.S152718 |
0.383 |
|
2015 |
Shen YC, Upadhyayula R, Cevallos S, Messick RJ, Hsia T, Leese MP, Jewett DM, Ferrer-Torres D, Roth TM, Dohle W, Potter BV, Barald KF. Targeted NF1 cancer therapeutics with multiple modes of action: small molecule hormone-like agents resembling the natural anticancer metabolite, 2-methoxyoestradiol. British Journal of Cancer. 113: 1158-67. PMID 26461061 DOI: 10.1038/Bjc.2015.345 |
0.439 |
|
2014 |
Dohle W, Leese MP, Jourdan FL, Chapman CJ, Hamel E, Ferrandis E, Potter BV. Optimisation of tetrahydroisoquinoline-based chimeric microtubule disruptors. Chemmedchem. 9: 1783-93. PMID 24819406 DOI: 10.1002/Cmdc.201402025 |
0.48 |
|
2014 |
Leese MP, Jourdan FL, Major MR, Dohle W, Thomas MP, Hamel E, Ferrandis E, Mahon MF, Newman SP, Purohit A, Potter BV. Synthesis, anti-tubulin and antiproliferative SAR of steroidomimetic dihydroisoquinolinones. Chemmedchem. 9: 798-812. PMID 24596315 DOI: 10.1002/Cmdc.201400017 |
0.5 |
|
2014 |
Dohle W, Leese MP, Jourdan FL, Major MR, Bai R, Hamel E, Ferrandis E, Kasprzyk PG, Fiore A, Newman SP, Purohit A, Potter BV. Synthesis, antitubulin, and antiproliferative SAR of C3/C1-substituted tetrahydroisoquinolines. Chemmedchem. 9: 350-70. PMID 24436228 DOI: 10.1002/Cmdc.201300412 |
0.519 |
|
2014 |
Leese MP, Jourdan FL, Major MR, Dohle W, Hamel E, Ferrandis E, Fiore A, Kasprzyk PG, Potter BV. Tetrahydroisoquinolinone-based steroidomimetic and chimeric microtubule disruptors. Chemmedchem. 9: 85-108, 1. PMID 24124095 DOI: 10.1002/Cmdc.201300261 |
0.523 |
|
2012 |
Leese MP, Jourdan F, Dohle W, Kimberley MR, Thomas MP, Bai R, Hamel E, Ferrandis E, Potter BV. Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors. Acs Medicinal Chemistry Letters. 3: 5-9. PMID 22247790 DOI: 10.1021/Ml200232C |
0.495 |
|
2011 |
Jourdan F, Leese MP, Dohle W, Ferrandis E, Newman SP, Chander S, Purohit A, Potter BV. Structure-activity relationships of C-17-substituted estratriene-3-O-sulfamates as anticancer agents. Journal of Medicinal Chemistry. 54: 4863-79. PMID 21604672 DOI: 10.1021/Jm200483X |
0.523 |
|
2010 |
Jourdan F, Leese MP, Dohle W, Hamel E, Ferrandis E, Newman SP, Purohit A, Reed MJ, Potter BV. Synthesis, antitubulin, and antiproliferative SAR of analogues of 2-methoxyestradiol-3,17-O,O-bis-sulfamate. Journal of Medicinal Chemistry. 53: 2942-51. PMID 20225862 DOI: 10.1021/Jm9018806 |
0.526 |
|
2009 |
Lainchbury MD, Medley MI, Taylor PM, Hirst P, Dohle W, Booker-Milburn KI. Synthesis of ()-Neostenine Synfacts. 2009: 240-240. DOI: 10.1055/S-0028-1087693 |
0.409 |
|
2008 |
Lainchbury MD, Medley MI, Taylor PM, Hirst P, Dohle W, Booker-Milburn KI. A protecting group free synthesis of (+/-)-neostenine via the [5 + 2] photocycloaddition of maleimides. The Journal of Organic Chemistry. 73: 6497-505. PMID 18656978 DOI: 10.1021/Jo801108H |
0.412 |
|
2006 |
Borthwick S, Dohle W, Hirst PR, Booker-Milburn KI. Copper-catalysed meso-bislactone ring opening using Grignard and mixed triorganozinc reagents Tetrahedron Letters. 47: 7205-7208. DOI: 10.1016/J.Tetlet.2006.07.146 |
0.395 |
|
2005 |
Hook BD, Dohle W, Hirst PR, Pickworth M, Berry MB, Booker-Milburn KI. A practical flow reactor for continuous organic photochemistry. The Journal of Organic Chemistry. 70: 7558-64. PMID 16149784 DOI: 10.1021/Jo050705P |
0.313 |
|
2003 |
Dohle W, Staubitz A, Knochel P. Mild synthesis of polyfunctional benzimidazoles and indoles by the reduction of functionalized nitroarenes with phenylmagnesium chloride. Chemistry (Weinheim An Der Bergstrasse, Germany). 9: 5323-31. PMID 14613142 DOI: 10.1002/Chem.200305090 |
0.526 |
|
2003 |
Knochel P, Dohle W, Gommermann N, Kneisel FF, Kopp F, Korn T, Sapountzis I, Vu VA. Highly functionalized organomagnesium reagents prepared through halogen-metal exchange. Angewandte Chemie (International Ed. in English). 42: 4302-20. PMID 14502700 DOI: 10.1002/Anie.200300579 |
0.606 |
|
2003 |
Staubitz A, Dohle W, Knochel P. Expeditious Functionalization of Quinolines in Positions 2 and 8 via Polyfunctional Aryl- and Heteroarylmagnesium Intermediates Cheminform. 34. DOI: 10.1055/S-2003-36828 |
0.595 |
|
2003 |
Koradin C, Dohle W, Rodriguez AL, Schmid B, Knochel P. Synthesis of polyfunctional indoles and related heterocycles mediated by cesium and potassium bases Tetrahedron. 59: 1571-1587. DOI: 10.1016/S0040-4020(03)00073-5 |
0.787 |
|
2003 |
Knochel P, Dohle W, Gommermann N, Kneisel FF, Kopp F, Korn T, Sapountzis I, Vu VA. Synthese hoch funktionalisierter Organomagnesiumreagentien durch Halogen-Metall-Austausch Angewandte Chemie. 115: 4438-4456. DOI: 10.1002/Ange.200300579 |
0.376 |
|
2003 |
Staubitz A, Dohle W, Knochel P. Expeditious functionalization of quinolines in positions 2 and 8 via polyfunctional aryl- and heteroarylmagnesium intermediates Synthesis. 233-242. |
0.32 |
|
2002 |
Lindsay DM, Dohle W, Jensen AE, Kopp F, Knochel P. Preparation of polyfunctional heterocycles using highly functionalized aminated arylmagnesium reagents as versatile scaffolds. Organic Letters. 4: 1819-22. PMID 12027622 DOI: 10.1021/Ol025597X |
0.764 |
|
2002 |
Knochel P, Hupe E, Dohle W, Lindsay DM, Bonnet V, Quéguiner G, Boudier A, Kopp F, Demay S, Seidel N, Calaza MI, Vu VA, Sapountzis I, Bunlaksananusorn T. Functionalized main-group organometallics for organic synthesis Pure and Applied Chemistry. 74: 11-17. DOI: 10.1351/Pac200274010011 |
0.743 |
|
2002 |
Jensen AE, Dohle W, Sapountzis I, Lindsay DM, Vu VA, Knochel P. Preparation and Reactions of Functionalized Arylmagnesium Reagents Synthesis. 4: 565-569. DOI: 10.1055/S-2002-20955 |
0.732 |
|
2002 |
Knochel P, Hupe E, Dohle W, Lindsay DM, Bonnet V, Quéguiner G, Boudier A, Kopp F, Demay S, Seidel N, Calaza MI, Vu VA, Sapountzis I, Bunlaksananusorn T. Functionalized main-group organometallics for organic synthesis Pure and Applied Chemistry. 74: 11-17. |
0.681 |
|
2002 |
Jensen AE, Dohle W, Sapountzis I, Lindsay DM, Vu VA, Knochel P. Preparation and reactions of functionalized arylmagnesium reagents Synthesis. 565-569. |
0.736 |
|
2001 |
Sapountzis I, Dohle W, Knochel P. Stereoselective preparation of highly functionalized (Z)-3-magnesiated enoates by an iodine-magnesium exchange reaction. Chemical Communications (Cambridge, England). 2068-9. PMID 12240167 DOI: 10.1039/B106195J |
0.54 |
|
2001 |
Dohle W, Lindsay DM, Knochel P. Copper-mediated cross-coupling of functionalized arylmagnesium reagents with functionalized alkyl and benzylic halides. Organic Letters. 3: 2871-3. PMID 11529778 DOI: 10.1021/Ol0163272 |
0.676 |
|
2001 |
Dohle W, Kopp F, Cahiez G, Knochel P. Fe(III)-Catalyzed Cross-Coupling Between Functionalized Arylmagnesium Compounds and Alkenyl Halides Synlett. 2001: 1901-1904. DOI: 10.1055/S-2001-18748 |
0.427 |
|
2001 |
Varchi G, Eeg Jensen A, Dohle W, Ricci A, Cahiez G, Knochel P. Preparation of Functionalized Magnesiated Aniline Derivatives Synlett. 2001: 0477-0480. DOI: 10.1055/S-2001-12323 |
0.52 |
|
2001 |
Varchi G, Jensen AE, Dohle W, Ricci A, Cahiez G, Knochel P. Preparation of functionalized magnesiated aniline derivatives Synlett. 477-480. |
0.652 |
|
2000 |
Rodriguez AL, Koradin C, Dohle W, Knochel P. Versatile Indole Synthesis by a 5-endo-dig Cyclization Mediated by Potassium or Cesium Bases We thank the DFG (Leibniz-Programm) and the Fonds der Chemischen Industrie for generous financial support. A.L.R. and C. K. thank the Humboldt-Foundation and the BASF AG, respectively, for fellowships. W.D. was supported by the BMBF program (03 D 0056 2). We thank Dr. J. Henkelmann (BASF AG) for helpful discussions and the BASF AG for the generous gift of chemicals. Angewandte Chemie (International Ed. in English). 39: 2488-2490. PMID 10941112 DOI: 10.1002/1521-3773(20000717)39:14<2488::Aid-Anie2488>3.0.Co;2-E |
0.717 |
|
2000 |
Jensen AE, Dohle W, Knochel P. Improved Nickel-Catalyzed Cross-Coupling Reaction Conditions between ortho -Substituted Aryl Iodides/Nonaflates and Alkylzinc Iodides in Solution and in the Solid-Phase Tetrahedron. 56: 4197-4201. DOI: 10.1016/S0040-4020(00)00344-6 |
0.703 |
|
2000 |
Rodriguez A, Koradin C, Dohle W, Knochel P. Vielseitige Indolsynthese durch eine Kalium- oder Caesiumbasen-vermittelte 5-endo-dig-Cyclisierung Angewandte Chemie. 112: 2607-2609. DOI: 10.1002/1521-3757(20000717)112:14<2607::Aid-Ange2607>3.0.Co;2-I |
0.724 |
|
2000 |
Jensen AE, Dohle W, Knochel P. Improved nickel-catalyzed cross-coupling reaction conditions between ortho-substituted aryl iodides/nonaflates and alkylzinc iodides in solution and in the solid-phase Tetrahedron. 56: 4197-4201. |
0.641 |
|
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