Wolfgang Dohle - Publications

1999-2002 Ludwig-Maximilians-Universität München, München, Bayern, Germany 

32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Löhndorf A, Hosang L, Dohle W, Odoardi F, Waschkowski SA, Rosche A, Bauche A, Winzer R, Tolosa E, Windhorst S, Marry S, Flügel A, Potter BVL, Diercks BP, Guse AH. 2-Methoxyestradiol and its derivatives inhibit store-operated Ca entry in T cells: identification of a new and potent inhibitor. Biochimica Et Biophysica Acta. Molecular Cell Research. 118988. PMID 33581218 DOI: 10.1016/j.bbamcr.2021.118988  0.56
2020 Su X, Dohle W, Mills SJ, Watt JM, Rossi AM, Taylor CW, Potter BVL. Inositol Adenophostin: Convergent Synthesis of a Potent Agonist of d--Inositol 1,4,5-Trisphosphate Receptors. Acs Omega. 5: 28793-28811. PMID 33195933 DOI: 10.1021/acsomega.0c04145  0.56
2019 Shen YC, Arellano-Garcia C, Menjivar RE, Jewett EM, Dohle W, Karchugina S, Chernoff J, Potter BVL, Barald KF. Nonsteroidal sulfamate derivatives as new therapeutic approaches for Neurofibromatosis 2 (NF2). Bmc Pharmacology & Toxicology. 20: 67. PMID 31730023 DOI: 10.1186/S40360-019-0369-8  0.56
2019 Dohle W, Su X, Mills SJ, Rossi AM, Taylor CW, Potter BVL. A synthetic cyclitol-nucleoside conjugate polyphosphate is a highly potent second messenger mimic. Chemical Science. 10: 5382-5390. PMID 31171961 DOI: 10.1039/C9Sc00445A  0.56
2019 Dohle W, Prota AE, Menchon G, Hamel E, Steinmetz MO, Potter BVL. Tetrahydroisoquinoline Sulfamates as Potent Microtubule Disruptors: Synthesis, Antiproliferative and Antitubulin Activity of Dichlorobenzyl-Based Derivatives, and a Tubulin Cocrystal Structure. Acs Omega. 4: 755-764. PMID 30775645 DOI: 10.1021/acsomega.8b02879  0.56
2019 Andring J, Dohle W, Tu C, Potter BVL, McKenna R. 3,17β-Bis-sulfamoyloxy-2-methoxyestra-1,3,5(10)-triene (STX140) and Non-Steroidal Sulfamate Derivatives Inhibit Carbonic Anhydrase IX: Structure-Activity Optimization for Isoform Selectivity. Journal of Medicinal Chemistry. PMID 30721041 DOI: 10.1021/acs.jmedchem.8b01990  0.56
2018 Nel M, Joubert AM, Dohle W, Potter BV, Theron AE. Modes of cell death induced by tetrahydroisoquinoline-based analogs in MDA-MB-231 breast and A549 lung cancer cell lines. Drug Design, Development and Therapy. 12: 1881-1904. PMID 29983544 DOI: 10.2147/Dddt.S152718  0.44
2017 Dohle W, Jourdan FL, Menchon G, Prota AE, Foster PA, Mannion P, Hamel E, Thomas MP, Kasprzyk PG, Ferrandis E, Steinmetz MO, Leese MP, Potter BVL. Quinazolinone-based Anticancer Agents: Synthesis, Anti-proliferative SAR, Anti-tubulin Activity and Tubulin Co-crystal Structure. Journal of Medicinal Chemistry. PMID 29227648 DOI: 10.1021/Acs.Jmedchem.7B01474  0.56
2015 Shen YC, Upadhyayula R, Cevallos S, Messick RJ, Hsia T, Leese MP, Jewett DM, Ferrer-Torres D, Roth TM, Dohle W, Potter BV, Barald KF. Targeted NF1 cancer therapeutics with multiple modes of action: small molecule hormone-like agents resembling the natural anticancer metabolite, 2-methoxyoestradiol. British Journal of Cancer. 113: 1158-67. PMID 26461061 DOI: 10.1038/Bjc.2015.345  0.72
2014 Dohle W, Leese MP, Jourdan FL, Chapman CJ, Hamel E, Ferrandis E, Potter BV. Optimisation of tetrahydroisoquinoline-based chimeric microtubule disruptors. Chemmedchem. 9: 1783-93. PMID 24819406 DOI: 10.1002/Cmdc.201402025  0.72
2014 Leese MP, Jourdan FL, Major MR, Dohle W, Thomas MP, Hamel E, Ferrandis E, Mahon MF, Newman SP, Purohit A, Potter BV. Synthesis, anti-tubulin and antiproliferative SAR of steroidomimetic dihydroisoquinolinones. Chemmedchem. 9: 798-812. PMID 24596315 DOI: 10.1002/Cmdc.201400017  0.72
2014 Dohle W, Leese MP, Jourdan FL, Major MR, Bai R, Hamel E, Ferrandis E, Kasprzyk PG, Fiore A, Newman SP, Purohit A, Potter BV. Synthesis, antitubulin, and antiproliferative SAR of C3/C1-substituted tetrahydroisoquinolines. Chemmedchem. 9: 350-70. PMID 24436228 DOI: 10.1002/Cmdc.201300412  0.72
2014 Leese MP, Jourdan FL, Major MR, Dohle W, Hamel E, Ferrandis E, Fiore A, Kasprzyk PG, Potter BV. Tetrahydroisoquinolinone-based steroidomimetic and chimeric microtubule disruptors. Chemmedchem. 9: 85-108, 1. PMID 24124095 DOI: 10.1002/Cmdc.201300261  0.72
2012 Leese MP, Jourdan F, Dohle W, Kimberley MR, Thomas MP, Bai R, Hamel E, Ferrandis E, Potter BV. Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors. Acs Medicinal Chemistry Letters. 3: 5-9. PMID 22247790 DOI: 10.1021/Ml200232C  0.72
2011 Jourdan F, Leese MP, Dohle W, Ferrandis E, Newman SP, Chander S, Purohit A, Potter BV. Structure-activity relationships of C-17-substituted estratriene-3-O-sulfamates as anticancer agents. Journal of Medicinal Chemistry. 54: 4863-79. PMID 21604672 DOI: 10.1021/Jm200483X  0.56
2010 Jourdan F, Leese MP, Dohle W, Hamel E, Ferrandis E, Newman SP, Purohit A, Reed MJ, Potter BV. Synthesis, antitubulin, and antiproliferative SAR of analogues of 2-methoxyestradiol-3,17-O,O-bis-sulfamate. Journal of Medicinal Chemistry. 53: 2942-51. PMID 20225862 DOI: 10.1021/Jm9018806  0.72
2008 Lainchbury MD, Medley MI, Taylor PM, Hirst P, Dohle W, Booker-Milburn KI. A protecting group free synthesis of (+/-)-neostenine via the [5 + 2] photocycloaddition of maleimides. The Journal of Organic Chemistry. 73: 6497-505. PMID 18656978 DOI: 10.1021/Jo801108H  0.72
2006 Borthwick S, Dohle W, Hirst PR, Booker-Milburn KI. Copper-catalysed meso-bislactone ring opening using Grignard and mixed triorganozinc reagents Tetrahedron Letters. 47: 7205-7208. DOI: 10.1016/J.Tetlet.2006.07.146  0.72
2005 Hook BD, Dohle W, Hirst PR, Pickworth M, Berry MB, Booker-Milburn KI. A practical flow reactor for continuous organic photochemistry. The Journal of Organic Chemistry. 70: 7558-64. PMID 16149784 DOI: 10.1021/Jo050705P  0.72
2003 Dohle W, Staubitz A, Knochel P. Mild synthesis of polyfunctional benzimidazoles and indoles by the reduction of functionalized nitroarenes with phenylmagnesium chloride. Chemistry (Weinheim An Der Bergstrasse, Germany). 9: 5323-31. PMID 14613142 DOI: 10.1002/Chem.200305090  0.72
2003 Knochel P, Dohle W, Gommermann N, Kneisel FF, Kopp F, Korn T, Sapountzis I, Vu VA. Highly functionalized organomagnesium reagents prepared through halogen-metal exchange. Angewandte Chemie (International Ed. in English). 42: 4302-20. PMID 14502700 DOI: 10.1002/Anie.200300579  0.72
2003 Koradin C, Dohle W, Rodriguez AL, Schmid B, Knochel P. Synthesis of polyfunctional indoles and related heterocycles mediated by cesium and potassium bases Tetrahedron. 59: 1571-1587. DOI: 10.1016/S0040-4020(03)00073-5  0.72
2003 Staubitz A, Dohle W, Knochel P. Expeditious functionalization of quinolines in positions 2 and 8 via polyfunctional aryl- and heteroarylmagnesium intermediates Synthesis. 233-242.  0.72
2002 Lindsay DM, Dohle W, Jensen AE, Kopp F, Knochel P. Preparation of polyfunctional heterocycles using highly functionalized aminated arylmagnesium reagents as versatile scaffolds. Organic Letters. 4: 1819-22. PMID 12027622 DOI: 10.1021/Ol025597X  0.72
2002 Jensen AE, Dohle W, Sapountzis I, Lindsay DM, Vu VA, Knochel P. Preparation and reactions of functionalized arylmagnesium reagents Synthesis. 565-569.  0.72
2002 Knochel P, Hupe E, Dohle W, Lindsay DM, Bonnet V, Quéguiner G, Boudier A, Kopp F, Demay S, Seidel N, Calaza MI, Vu VA, Sapountzis I, Bunlaksananusorn T. Functionalized main-group organometallics for organic synthesis Pure and Applied Chemistry. 74: 11-17.  0.72
2001 Sapountzis I, Dohle W, Knochel P. Stereoselective preparation of highly functionalized (Z)-3-magnesiated enoates by an iodine-magnesium exchange reaction. Chemical Communications (Cambridge, England). 2068-9. PMID 12240167 DOI: 10.1039/B106195J  0.72
2001 Dohle W, Lindsay DM, Knochel P. Copper-mediated cross-coupling of functionalized arylmagnesium reagents with functionalized alkyl and benzylic halides. Organic Letters. 3: 2871-3. PMID 11529778 DOI: 10.1021/Ol0163272  0.72
2001 Dohle W, Kopp F, Cahiez G, Knochel P. Fe(III)-catalyzed cross-coupling between functionalized arylmagnesium compounds and alkenyl halides Synlett. 1901-1904.  0.72
2001 Varchi G, Jensen AE, Dohle W, Ricci A, Cahiez G, Knochel P. Preparation of functionalized magnesiated aniline derivatives Synlett. 477-480.  0.72
2000 Rodriguez AL, Koradin C, Dohle W, Knochel P. Versatile Indole Synthesis by a 5-endo-dig Cyclization Mediated by Potassium or Cesium Bases We thank the DFG (Leibniz-Programm) and the Fonds der Chemischen Industrie for generous financial support. A.L.R. and C. K. thank the Humboldt-Foundation and the BASF AG, respectively, for fellowships. W.D. was supported by the BMBF program (03 D 0056 2). We thank Dr. J. Henkelmann (BASF AG) for helpful discussions and the BASF AG for the generous gift of chemicals. Angewandte Chemie (International Ed. in English). 39: 2488-2490. PMID 10941112 DOI: 10.1002/1521-3773(20000717)39:14<2488::Aid-Anie2488>3.0.Co;2-E  0.72
2000 Jensen AE, Dohle W, Knochel P. Improved nickel-catalyzed cross-coupling reaction conditions between ortho-substituted aryl iodides/nonaflates and alkylzinc iodides in solution and in the solid-phase Tetrahedron. 56: 4197-4201.  0.72
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