Thom Gaj - Publications

Affiliations: 
2007 University of Arizona, Tucson, AZ 

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Limsirichai P, Gaj T, Schaffer DV. CRISPR-mediated activation of latent HIV-1 expression. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26607397 DOI: 10.1038/mt.2015.213  0.72
2015 Liu J, Gaj T, Yang Y, Wang N, Shui S, Kim S, Kanchiswamy CN, Kim JS, Barbas CF. Efficient delivery of nuclease proteins for genome editing in human stem cells and primary cells. Nature Protocols. 10: 1842-1859. PMID 26492140 DOI: 10.1038/nprot.2015.117  0.72
2015 Wallen MC, Gaj T, Barbas CF. Redesigning Recombinase Specificity for Safe Harbor Sites in the Human Genome. Plos One. 10: e0139123. PMID 26414179 DOI: 10.1371/journal.pone.0139123  0.72
2015 Gaj T, Epstein BE, Schaffer DV. Genome Engineering Using Adeno-associated Virus: Basic and Clinical Research Applications. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26373345 DOI: 10.1038/mt.2015.151  0.72
2015 Gaj T, Liu J. Direct protein delivery to mammalian cells using cell-permeable Cys2-His2 zinc-finger domains. Journal of Visualized Experiments : Jove. PMID 25866937 DOI: 10.3791/52814  0.72
2015 Liu J, Gaj T, Wallen MC, Barbas CF. Improved cell-penetrating zinc-finger nuclease proteins for precision genome engineering. Molecular Therapy. Nucleic Acids. 4: e232. PMID 25756962 DOI: 10.1038/mtna.2015.6  0.72
2014 Gaj T, Barbas CF. Genome engineering with custom recombinases. Methods in Enzymology. 546: 79-91. PMID 25398336 DOI: 10.1016/B978-0-12-801185-0.00004-0  0.72
2014 Asano S, Patterson JT, Gaj T, Barbas CF. Site-selective labeling of a lysine residue in human serum albumin. Angewandte Chemie (International Ed. in English). 53: 11783-6. PMID 25196737 DOI: 10.1002/anie.201405924  0.72
2014 Gaj T, Liu J, Anderson KE, Sirk SJ, Barbas CF. Protein delivery using Cys2-His2 zinc-finger domains. Acs Chemical Biology. 9: 1662-7. PMID 24936957 DOI: 10.1021/cb500282g  0.72
2014 Gersbach CA, Gaj T, Barbas CF. Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies. Accounts of Chemical Research. 47: 2309-18. PMID 24877793 DOI: 10.1021/ar500039w  0.72
2014 Gaj T, Sirk SJ, Tingle RD, Mercer AC, Wallen MC, Barbas CF. Enhancing the specificity of recombinase-mediated genome engineering through dimer interface redesign. Journal of the American Chemical Society. 136: 5047-56. PMID 24611715 DOI: 10.1021/ja4130059  0.72
2014 Liu J, Gaj T, Patterson JT, Sirk SJ, Barbas CF. Cell-penetrating peptide-mediated delivery of TALEN proteins via bioconjugation for genome engineering. Plos One. 9: e85755. PMID 24465685 DOI: 10.1371/journal.pone.0085755  0.72
2014 Sirk SJ, Gaj T, Jonsson A, Mercer AC, Barbas CF. Expanding the zinc-finger recombinase repertoire: directed evolution and mutational analysis of serine recombinase specificity determinants. Nucleic Acids Research. 42: 4755-66. PMID 24452803 DOI: 10.1093/nar/gkt1389  0.72
2014 Mercer AC, Gaj T, Sirk SJ, Lamb BM, Barbas CF. Regulation of endogenous human gene expression by ligand-inducible TALE transcription factors. Acs Synthetic Biology. 3: 723-30. PMID 24251925 DOI: 10.1021/sb400114p  0.72
2014 Gaj T, Sirk SJ, Barbas CF. Expanding the scope of site-specific recombinases for genetic and metabolic engineering. Biotechnology and Bioengineering. 111: 1-15. PMID 23982993 DOI: 10.1002/bit.25096  0.72
2014 Gersbach CA, Gaj T, Barbas CF. Comparing genome editing technologies Genetic Engineering and Biotechnology News. 34: 1+32-34. DOI: 10.1089/gen.34.05.02  0.72
2013 Gaj T, Gersbach CA, Barbas CF. ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering. Trends in Biotechnology. 31: 397-405. PMID 23664777 DOI: 10.1016/j.tibtech.2013.04.004  0.72
2013 Gaj T, Mercer AC, Sirk SJ, Smith HL, Barbas CF. A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cells. Nucleic Acids Research. 41: 3937-46. PMID 23393187 DOI: 10.1093/nar/gkt071  0.72
2012 Mercer AC, Gaj T, Fuller RP, Barbas CF. Chimeric TALE recombinases with programmable DNA sequence specificity. Nucleic Acids Research. 40: 11163-72. PMID 23019222 DOI: 10.1093/nar/gks875  0.72
2012 Gaj T, Guo J, Kato Y, Sirk SJ, Barbas CF. Targeted gene knockout by direct delivery of zinc-finger nuclease proteins. Nature Methods. 9: 805-7. PMID 22751204 DOI: 10.1038/nmeth.2030  0.72
2011 Gersbach CA, Gaj T, Gordley RM, Mercer AC, Barbas CF. Targeted plasmid integration into the human genome by an engineered zinc-finger recombinase. Nucleic Acids Research. 39: 7868-78. PMID 21653554 DOI: 10.1093/nar/gkr421  0.72
2011 Gaj T, Mercer AC, Gersbach CA, Gordley RM, Barbas CF. Structure-guided reprogramming of serine recombinase DNA sequence specificity. Proceedings of the National Academy of Sciences of the United States of America. 108: 498-503. PMID 21187418 DOI: 10.1073/pnas.1014214108  0.72
2011 Chung HS, Raetz CR. Dioxygenases in Burkholderia ambifaria and Yersinia pestis that hydroxylate the outer Kdo unit of lipopolysaccharide. Proceedings of the National Academy of Sciences of the United States of America. 108: 510-5. PMID 21178073 DOI: 10.1073/pnas.1016462108  0.72
2010 Guo J, Gaj T, Barbas CF. Directed evolution of an enhanced and highly efficient FokI cleavage domain for zinc finger nucleases. Journal of Molecular Biology. 400: 96-107. PMID 20447404 DOI: 10.1016/j.jmb.2010.04.060  0.72
2010 Gersbach CA, Gaj T, Gordley RM, Barbas CF. Directed evolution of recombinase specificity by split gene reassembly. Nucleic Acids Research. 38: 4198-206. PMID 20194120 DOI: 10.1093/nar/gkq125  0.72
2007 Meyer SC, Shomin CD, Gaj T, Ghosh I. Tethering small molecules to a phage display library: discovery of a selective bivalent inhibitor of protein kinase A. Journal of the American Chemical Society. 129: 13812-3. PMID 17944472 DOI: 10.1021/ja076197d  0.72
2007 Gaj T, Meyer SC, Ghosh I. The AviD-tag, a NeutrAvidin/avidin specific peptide affinity tag for the immobilization and purification of recombinant proteins. Protein Expression and Purification. 56: 54-61. PMID 17697784 DOI: 10.1016/j.pep.2007.06.010  0.72
2006 Meyer SC, Gaj T, Ghosh I. Highly selective cyclic peptide ligands for NeutrAvidin and avidin identified by phage display. Chemical Biology & Drug Design. 68: 3-10. PMID 16923020 DOI: 10.1111/j.1747-0285.2006.00401.x  0.72
1973 Gaj T, Grendus-Tota B. [Familial atrophic form of spinocerebellar ataxia]. Neurologia I Neurochirurgia Polska. 7: 679-83. PMID 4763007  0.01
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