Minying Cai - Publications

Affiliations: 
2003- University of Arizona, Tucson, AZ 

111 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zhou Y, Banday AH, Hruby VJ, Cai M. Development of -Acetylated Dipalmitoyl--Glyceryl Cysteine Analogs as Efficient TLR2/TLR6 Agonists. Molecules (Basel, Switzerland). 24. PMID 31569697 DOI: 10.3390/molecules24193512  1
2018 Zhou Y, Mowlazadeh Haghighi S, Zoi I, Sawyer JR, Hruby VJ, Cai M. Correction to Design of MC1R Selective γ-MSH Analogues with Canonical Amino Acids Leads to Potency and Pigmentation. Journal of Medicinal Chemistry. PMID 30252463 DOI: 10.1021/acs.jmedchem.8b01423  1
2018 Eerola K, Virtanen S, Vähätalo L, Ailanen L, Cai M, Hruby V, Savontaus M, Savontaus E. Hypothalamic γ-melanocyte stimulating hormone gene delivery reduces fat mass in male mice. The Journal of Endocrinology. PMID 30006340 DOI: 10.1530/JOE-18-0009  0.4
2018 Mowlazadeh Haghighi S, Zhou Y, Dai J, Sawyer JR, Hruby VJ, Cai M. Replacement of Arg with Nle and modified D-Phe in the core sequence of MSHs, Ac-His-D-Phe-Arg-Trp-NH, leads to hMC1R selectivity and pigmentation. European Journal of Medicinal Chemistry. 151: 815-823. PMID 29679901 DOI: 10.1016/j.ejmech.2018.04.021  1
2018 Merlino F, Zhou Y, Cai M, Carotenuto A, Yousif AM, Brancaccio D, Di Maro S, Zappavigna S, Limatola A, Novellino E, Grieco P, Hruby VJ. Development of Macrocyclic Peptidomimetics Containing Constrained α,α-Dialkylated Amino Acids with Potent and Selective Activity at Human Melanocortin Receptors. Journal of Medicinal Chemistry. PMID 29660981 DOI: 10.1021/acs.jmedchem.8b00488  1
2018 Durek T, Cromm PM, White AM, Schroeder CI, Kaas Q, Weidmann J, Ahmad Fuaad A, Cheneval O, Harvey PJ, Daly NL, Zhou Y, Dellsén A, Österlund T, Larsson N, Knerr L, ... Cai M, et al. Development of novel melanocortin receptor agonists based on the cyclic peptide framework of sunflower trypsin inhibitor-1. Journal of Medicinal Chemistry. PMID 29605997 DOI: 10.1021/acs.jmedchem.8b00170  1
2017 Zhou Y, Mowlazadeh Haghighi S, Zoi I, Sawyer JR, Hruby VJ, Cai M. Design of MC1R selective γ-MSH analogues with canonical amino acids leads to potency and pigmentation. Journal of Medicinal Chemistry. PMID 29094944 DOI: 10.1021/acs.jmedchem.7b01295  1
2017 Cai M, Marelli UK, Mertz B, Beck JG, Opperer F, Rechenmacher F, Kessler H, Hruby VJ. Structural Insights into Selective Ligand-Receptor Interactions Leading to Receptor Inactivation Utilizing Selective Melanocortin 3 Receptor Antagonists. Biochemistry. PMID 28715181 DOI: 10.1021/acs.biochem.7b00407  1
2017 Rinne P, Rami M, Nuutinen SL, Santovito D, van der Vorst EPC, Guillamat-Prats R, Lyytikäinen LP, Raitoharju E, Oksala N, Ring L, Cai M, Hruby VJ, Lehtimäki TJ, Weber C, Steffens S. Melanocortin 1 Receptor Signaling Regulates Cholesterol Transport in Macrophages. Circulation. PMID 28450348 DOI: 10.1161/CIRCULATIONAHA.116.025889  1
2016 Liu Z, Gray BD, Barber C, Bernas M, Cai M, Furenlid LR, Rouse A, Patel C, Banerjee B, Liang R, Gmitro AF, Witte MH, Pak KY, Woolfenden JM. Characterization of TCP-1 probes for molecular imaging of colon cancer. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27574992 DOI: 10.1016/j.jconrel.2016.08.033  1
2016 Cai M, Hruby VJ. Design of Cyclized Selective Melanotropins. Biopolymers. PMID 27561155 DOI: 10.1002/bip.22976  1
2016 Cai M, Hruby VJ. The Melanocortin Receptor System: A Target for Multiple Degenerative Diseases. Current Protein & Peptide Science. PMID 26916163  1
2016 Cai M, Jiang S, Zeng Z, Li X, Mo C, Yang Y, Chen C, Xie P, Bian Y, Wang J, Huang J, Chen D, Peng T, Li M. Probing the nuclear import signal and nuclear transport molecular determinants of PRV ICP22. Cell & Bioscience. 6: 3. PMID 26816613 DOI: 10.1186/s13578-016-0069-7  0.4
2016 Gu X, Cai Z, Cai M, Liu K, Liu D, Zhang Q, Tan J, Ma Q. Protective effect of paeoniflorin on inflammation and apoptosis in the cerebral cortex of a transgenic mouse model of Alzheimer's disease. Molecular Medicine Reports. PMID 26796245 DOI: 10.3892/mmr.2016.4805  0.52
2016 Cai M, Ma Y, Zhang W, Wang S, Wang Y, Tian L, Peng Z, Wang H, Qingrong T. Apigenin-7-O-β-D-(-6''-p-coumaroyl)-Glucopyranoside Treatment Elicits Neuroprotective Effect against Experimental Ischemic Stroke. International Journal of Biological Sciences. 12: 42-52. PMID 26722216 DOI: 10.7150/ijbs.12275  0.48
2016 Lu Y, Cai M, Cao R, Qian S, Xu S, Zhang J. Er3+ doped germanate-tellurite glass for mid-infrared 2.7μm fiber laser material Journal of Quantitative Spectroscopy and Radiative Transfer. 171: 73-81. DOI: 10.1016/j.jqsrt.2015.12.014  1
2016 Yang Y, Ren RC, Cai M. Towards a physical understanding of stratospheric cooling under global warming through a process-based decomposition method Climate Dynamics. 1-16. DOI: 10.1007/s00382-016-3040-8  0.4
2015 Sastry N, Zheng W, Liu G, Wang H, Chen X, Cai M, Contractor P, Sgobio C, Sun L, Xie C, Cai H. No apparent transmission of transgenic α-synuclein into nigrostriatal dopaminergic neurons in multiple mouse models. Translational Neurodegeneration. 4: 23. PMID 26635953 DOI: 10.1186/s40035-015-0046-9  0.48
2015 Cai M, Zhang Y, Ma Y, Li W, Min P, Qiu J, Xu W, Zhang M, Li M, Li L, Liu Y, Yang D, Zhang J, Cheng F. Association between microRNA-499 polymorphism and gastric cancer risk in Chinese population. Bulletin Du Cancer. PMID 26597478 DOI: 10.1016/j.bulcan.2015.09.012  1
2015 Wang C, Zhang J, Cai M, Zhu Z, Gu W, Yu Y, Zhang X. DBGC: A Database of Human Gastric Cancer. Plos One. 10: e0142591. PMID 26566288 DOI: 10.1371/journal.pone.0142591  1
2015 Xiao Q, Gu M, Yang H, Li B, Zhang C, Liu Y, Liu F, Dai F, Yang L, Liu Z, Xiao X, Liu G, Zhao P, Zhang S, Wang C, ... ... Cai M, et al. Inward lithium-ion breathing of hierarchically porous silicon anodes. Nature Communications. 6: 8844. PMID 26538181 DOI: 10.1038/ncomms9844  0.6
2015 Cai M, Nie Y, Chi CQ, Tang YQ, Li Y, Wang XB, Liu ZS, Yang Y, Zhou J, Wu XL. Crude oil as a microbial seed bank with unexpected functional potentials. Scientific Reports. 5: 16057. PMID 26525361 DOI: 10.1038/srep16057  0.4
2015 Li M, Jiang S, Mo C, Wang J, Huang J, Zeng Z, Li X, Chen C, Yang Y, Peng T, Cai M. Identification of molecular determinants for the nuclear import of pseudorabies virus UL31. Archives of Biochemistry and Biophysics. PMID 26450651 DOI: 10.1016/j.abb.2015.09.024  0.4
2015 Liu Z, Yu T, Sun S, Wang S, Xiao L, Li Z, Cai M, Shi B. [Cytomegalovirus infection down-regulates the expressions of CD226 and CD16 in blood NK cells of the renal transplant recipient]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. 31: 1391-5. PMID 26429542  0.6
2015 Shukla C, Koch LG, Britton SL, Cai M, Hruby VJ, Bednarek M, Novak CM. Contribution of regional brain melanocortin receptor subtypes to elevated activity energy expenditure in lean, active rats. Neuroscience. PMID 26404873 DOI: 10.1016/j.neuroscience.2015.09.035  1
2015 Deng L, Gao Y, Li X, Cai M, Wang H, Zhuang H, Tan M, Liu S, Hao Y, Lin B. Expression and clinical significance of annexin A2 and human epididymis protein 4 in endometrial carcinoma. Journal of Experimental & Clinical Cancer Research : Cr. 34: 96. PMID 26362938 DOI: 10.1186/s13046-015-0208-8  0.48
2015 Cai M, Zhang J. Epidemiological Characteristics of Work-Related Ocular Trauma in Southwest Region of China. International Journal of Environmental Research and Public Health. 12: 9864-75. PMID 26295403 DOI: 10.3390/ijerph120809864  1
2015 Cai M, Zhou B, Wang F, Wei T, Tian Y, Zhou J, Xu S, Zhang J. R2O3 (R = La, Y) modified erbium activated germanate glasses for mid-infrared 2.7 μm laser materials. Scientific Reports. 5: 13056. PMID 26279092 DOI: 10.1038/srep13056  1
2015 Cai M, Marelli UK, Bao J, Beck JG, Opperer F, Rechenmacher F, McLeod KR, Zingsheim MR, Doedens L, Kessler H, Hruby VJ. Systematic Backbone Conformational Constraints on a Cyclic Melanotropin Ligand Leads to Highly Selective Ligands for Multiple Melanocortin Receptors. Journal of Medicinal Chemistry. 58: 6359-67. PMID 26218460 DOI: 10.1021/acs.jmedchem.5b00102  1
2015 Li M, Jiang S, Wang J, Mo C, Zeng Z, Yang Y, Chen C, Li X, Cui W, Huang J, Peng T, Cai M. Characterization of the nuclear import and export signals of pseudorabies virus UL31. Archives of Virology. PMID 26195191 DOI: 10.1007/s00705-015-2527-7  0.4
2015 Yan J, Zheng X, Liu Z, Yu J, Deng Z, Xue F, Zheng Y, Chen F, Shi H, Chen G, Lu J, Cai L, Cai M, Xiang G, Hong Y, et al. A multicenter study of using carbon nanoparticles to show sentinel lymph nodes in early gastric cancer. Surgical Endoscopy. PMID 26150223 DOI: 10.1007/s00464-015-4358-8  0.6
2015 Xu H, Hao X, Wang S, Wang Z, Cai M, Jiang J, Qin Q, Zhang M, Wang H. Real-time Imaging of Rabies Virus Entry into Living Vero cells. Scientific Reports. 5: 11753. PMID 26148807 DOI: 10.1038/srep11753  0.48
2015 Cai M, Su Z, Zou H, Zhang Q, Shen J, Zhang L, Wang T, Yang Z, Li C. Association between the traditional Chinese medicine pathological factors of opioid addiction and DRD2/ANKK1 TaqIA polymorphisms. Bmc Complementary and Alternative Medicine. 15: 209. PMID 26138154 DOI: 10.1186/s12906-015-0727-z  0.32
2015 Cai M, Wang Z, Zhang J, Zhou H, Jin L, Bai R, Weng Y. Adam17, a Target of Mir-326, Promotes Emt-Induced Cells Invasion in Lung Adenocarcinoma. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 36: 1175-1185. PMID 26111641 DOI: 10.1159/000430288  1
2015 Wei T, Tian Y, Tian C, Cai M, Jing X, Li B, Chen R, Zhang J, Xu S. Quantitative Analysis of Energy Transfer and Origin of Quenching in Er(3+)/Ho(3+) Codoped Germanosilicate Glasses. The Journal of Physical Chemistry. A. 119: 6823-30. PMID 26061719 DOI: 10.1021/acs.jpca.5b04537  1
2015 Yang F, Gardner CO, Bigdeli T, Gao J, Zhang Z, Tao M, Liu Y, Li Y, Wang G, Shi J, Gao C, Zhang K, Li K, Wang X, Liu L, ... ... Cai M, et al. Clinical features of and risk factors for major depression with history of postpartum episodes in Han Chinese women: A retrospective study. Journal of Affective Disorders. 183: 339-46. PMID 26052079 DOI: 10.1016/j.jad.2015.05.033  1
2015 Yang Y, Zan P, Gong J, Cai M. d-Dimer as a Screening Marker for Venous Thromboembolism After Surgery Among Patients Younger Than 50 With Lower Limb Fractures. Clinical and Applied Thrombosis/Hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. PMID 26045546 DOI: 10.1177/1076029615588784  0.4
2015 Zhang J, Cheng W, Cai M. Effects of electroacupuncture on overactive bladder refractory to anticholinergics: a single-blind randomised controlled trial. Acupuncture in Medicine : Journal of the British Medical Acupuncture Society. PMID 26040492 DOI: 10.1136/acupmed-2015-010770  1
2015 Wang F, Cai M, Chen R, Jing X, Li B, Tian Y, Zhang J, Xu S. The influence of TeO2 on thermal stability and 1.53μm spectroscopic properties in Er(3+) doped oxyfluorite glasses. Spectrochimica Acta. Part a, Molecular and Biomolecular Spectroscopy. 150: 162-169. PMID 26037501 DOI: 10.1016/j.saa.2015.05.025  1
2015 Li W, Zhang J, Zheng Y, Chen G, Cai M, Wei B. The energy transfer mechanism of a photoexcited and electroluminescent organic hybrid thin film of blue, green, and red laser dyes. Nanoscale Research Letters. 10: 194. PMID 25977665 DOI: 10.1186/s11671-015-0899-y  1
2015 Liu P, Wu X, Shi H, Liu R, Shu H, Gong J, Yang Y, Sun Q, Wu J, Nie X, Cai M. Intramedullary versus extramedullary fixation in the management of subtrochanteric femur fractures: a meta-analysis. Clinical Interventions in Aging. 10: 803-11. PMID 25960644 DOI: 10.2147/CIA.S82119  0.4
2015 Ding B, Tian Y, Pan Y, Shan Y, Cai M, Xu H, Sun Y, Wang H. Recording the dynamic endocytosis of single gold nanoparticles by AFM-based force tracing. Nanoscale. 7: 7545-9. PMID 25864702 DOI: 10.1039/c5nr01020a  0.48
2015 Wang LJ, He CC, Sui X, Cai MJ, Zhou CY, Ma JL, Wu L, Wang H, Han SX, Zhu Q. MiR-21 promotes intrahepatic cholangiocarcinoma proliferation and growth in vitro and in vivo by targeting PTPN14 and PTEN. Oncotarget. 6: 5932-46. PMID 25803229  0.48
2015 Cai M, Zhang J, Guan L, Zhao M. Novel implantable composite biomaterial by fibrin glue and amniotic membrane for ocular surface reconstruction. Journal of Materials Science. Materials in Medicine. 26: 149. PMID 25764084 DOI: 10.1007/s10856-015-5491-6  1
2015 Gao J, Wang F, Liu Y, Cai M, Xu H, Jiang J, Wang H. Revealing the cellular localization of STAT1 during the cell cycle by super-resolution imaging. Scientific Reports. 5: 9045. PMID 25762114 DOI: 10.1038/srep09045  0.48
2015 Van der Poorten O, Fehér K, Buysse K, Feytens D, Zoi I, Schwartz SD, Martins JC, Tourwé D, Cai M, Hruby VJ, Ballet S. Azepinone-Containing Tetrapeptide Analogues of Melanotropin Lead to Selective hMC4R Agonists and hMC5R Antagonist. Acs Medicinal Chemistry Letters. 6: 192-7. PMID 25699148 DOI: 10.1021/ml500436s  1
2015 Pan Y, Wang S, Shan Y, Zhang D, Gao J, Zhang M, Liu S, Cai M, Xu H, Li G, Qin Q, Wang H. Ultrafast Tracking of a Single Live Virion During the Invagination of a Cell Membrane. Small (Weinheim An Der Bergstrasse, Germany). 11: 2782-8. PMID 25689837 DOI: 10.1002/smll.201403491  0.48
2015 Zhang M, Chen J, Gao J, Wang Z, Xu H, Cai M, Jiang J, Tian Z, Wang H. Magnetic-field-enabled resolution enhancement in super-resolution imaging. Physical Chemistry Chemical Physics : Pccp. 17: 6722-7. PMID 25688027 DOI: 10.1039/c4cp05914j  0.48
2015 Chen J, Gao J, Wu J, Zhang M, Cai M, Xu H, Jiang J, Tian Z, Wang H. Revealing the carbohydrate pattern on a cell surface by super-resolution imaging. Nanoscale. 7: 3373-80. PMID 25630278 DOI: 10.1039/c4nr05970k  0.48
2015 Gao J, Wang Y, Cai M, Pan Y, Xu H, Jiang J, Ji H, Wang H. Mechanistic insights into EGFR membrane clustering revealed by super-resolution imaging. Nanoscale. 7: 2511-9. PMID 25569174 DOI: 10.1039/c4nr04962d  0.48
2015 Liu R, Liu P, Shu H, Gong J, Sun Q, Wu J, Nie X, Yang Y, Cai M. Comparison of primary radial head replacement and ORIF (open reduction and internal fixation) in Mason type III fractures: a retrospective evaluation in 72 elderly patients. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 21: 90-3. PMID 25567738 DOI: 10.12659/MSM.893048  0.4
2015 Liu Y, Chai X, Hao Y, Gao X, Lu Z, Zhao Y, Zhang J, Cai M. Total mercury and methylmercury distributions in surface sediments from Kongsfjorden, Svalbard, Norwegian Arctic. Environmental Science and Pollution Research International. 22: 8603-10. PMID 25563828 DOI: 10.1007/s11356-014-3942-0  1
2015 Gu J, Lei Y, Huang Y, Zhao Y, Li J, Huang T, Zhang J, Wang J, Deng X, Chen Z, Korteweg C, Deng R, Yan M, Xu Q, Dong S, ... Cai M, et al. Fab fragment glycosylated IgG may play a central role in placental immune evasion. Human Reproduction (Oxford, England). 30: 380-91. PMID 25505012 DOI: 10.1093/humrep/deu323  1
2015 Cai M, Zhang J. Epidemiological characteristics of work-related ocular trauma in southwest region of China International Journal of Environmental Research and Public Health. 12: 9864-9875. DOI: 10.3390/ijerph120809864  1
2015 Li W, Zhang J, Zheng Y, Chen G, Cai M, Wei B. The energy transfer mechanism of a photoexcited and electroluminescent organic hybrid thin film of blue, green, and red laser dyes Nanoscale Research Letters. 10: 1-6. DOI: 10.1186/s11671-015-0899-y  1
2015 Zhou B, Wei T, Cai M, Tian Y, Zhou J, Deng D, Xu S, Zhang J. Observation of Midinfrared 4-μm Emission in Ho3+-Doped Fluoroaluminate Glasses Ieee Photonics Technology Letters. 27: 959-962. DOI: 10.1109/LPT.2015.2404032  1
2015 Cai M, Zhou B, Wang F, Tian Y, Zhou J, Xu S, Zhang J. Mid-infrared emission and quantitative analysis of energy transfer processes in Er3+ doped oxyfluogermanate glasses Journal of Applied Physics. 117. DOI: 10.1063/1.4923064  1
2015 Peng M, Xiao P, Huang Y, Cai M, Hou Y, Chen J, Liu Z, Xiao Z, Chen T. A direct microcontact printing induced supramolecular interaction for creating shape-tunable patterned polymeric surfaces Journal of Materials Chemistry C. 3: 8659-8664. DOI: 10.1039/c5tc01576f  0.6
2015 Cai M, Zhou B, Wang F, Wei T, Tian Y, Zhou J, Xu S, Zhang J. R2O3 (R = La, Y) modified erbium activated germanate glasses for mid-infrared 2.7 μm laser materials Scientific Reports. 5. DOI: 10.1038/srep13056  1
2015 Cai N, Bigdeli TB, Kretzschmar W, Lei Y, Liang J, Song L, Hu J, Li Q, Jin W, Hu Z, Wang G, Wang L, Qian P, Liu Y, Jiang T, ... ... Cai M, et al. Sparse whole-genome sequencing identifies two loci for major depressive disorder Nature. 523: 588-591. DOI: 10.1038/nature14659  1
2015 Cai M, Marelli UK, Bao J, Beck JG, Opperer F, Rechenmacher F, McLeod KR, Zingsheim MR, Doedens L, Kessler H, Hruby VJ. Systematic Backbone Conformational Constraints on a Cyclic Melanotropin Ligand Leads to Highly Selective Ligands for Multiple Melanocortin Receptors Journal of Medicinal Chemistry. 58: 6359-6367. DOI: 10.1021/acs.jmedchem.5b00102  1
2015 Wang F, Tian Y, Jing X, Cai M, Zhang J, Xu S. Effect of TeO2 addition on thermal stabilities and 2.7μm emission properties of fluoroaluminate-tellurite glass Journal of Quantitative Spectroscopy and Radiative Transfer. 165: 93-101. DOI: 10.1016/j.jqsrt.2015.06.027  1
2015 Wei T, Tian C, Cai M, Tian Y, Jing X, Zhang J, Xu S. Broadband 2μm fluorescence and energy transfer evaluation in Ho3+/Er3+ codoped germanosilicate glass Journal of Quantitative Spectroscopy and Radiative Transfer. 161: 95-104. DOI: 10.1016/j.jqsrt.2015.03.035  1
2014 Yang Y, Liu P, Guo F, Liu R, Yang Y, Huang C, Shu H, Gong J, Cai M. Genetic G2548A polymorphism of leptin gene and risk of cancer: a meta-analysis of 6860 cases and 7956 controls. Journal of B.U.On. : Official Journal of the Balkan Union of Oncology. 19: 1096-104. PMID 25536622  0.4
2014 Wu Y, Pan X, Zhang S, Wang W, Cai M, Li Y, Yang F, Guo H. Protective effect of corn peptides against alcoholic liver injury in men with chronic alcohol consumption: a randomized double-blind placebo-controlled study. Lipids in Health and Disease. 13: 192. PMID 25494594 DOI: 10.1186/1476-511X-13-192  0.84
2014 Sun S, Chen X, Gao Y, Liu Z, Zhai Q, Xiong L, Cai M, Wang Q. Mn-SOD Upregulation by Electroacupuncture Attenuates Ischemic Oxidative Damage via CB1R-Mediated STAT3 Phosphorylation. Molecular Neurobiology. PMID 25432886 DOI: 10.1007/s12035-014-8971-7  0.6
2013 Hruby VJ, Cai M. Design of peptide and peptidomimetic ligands with novel pharmacological activity profiles. Annual Review of Pharmacology and Toxicology. 53: 557-80. PMID 23294313 DOI: 10.1146/annurev-pharmtox-010510-100456  1
2013 Cai M, Stankova M, Muthu D, Mayorov A, Yang Z, Trivedi D, Cabello C, Hruby VJ. An unusual conformation of γ-melanocyte-stimulating hormone analogues leads to a selective human melanocortin 1 receptor antagonist for targeting melanoma cells. Biochemistry. 52: 752-64. PMID 23276279 DOI: 10.1021/bi300723f  1
2013 Rinne P, Nordlund W, Heinonen I, Penttinen AM, Saraste A, Ruohonen ST, Mäkelä S, Vähätalo L, Kaipio K, Cai M, Hruby VJ, Ruohonen S, Savontaus E. α-Melanocyte-stimulating hormone regulates vascular NO availability and protects against endothelial dysfunction. Cardiovascular Research. 97: 360-8. PMID 23131503 DOI: 10.1093/cvr/cvs335  1
2011 Hruby VJ, Cai M, Nyberg J, Muthu D. Approaches to the rational design of selective melanocortin receptor antagonists. Expert Opinion On Drug Discovery. 6: 543-57. PMID 22646078 DOI: 10.1517/17460441.2011.565743  1
2011 Mayorov AV, Cai M, Palmer ES, Tanaka DK, Cain JP, Dedek MM, Tan B, Trivedi D, Hruby VJ. Cyclic lactam hybrid α-MSH/Agouti-related protein (AGRP) analogues with nanomolar range binding affinities at the human melanocortin receptors. Bioorganic & Medicinal Chemistry Letters. 21: 3099-102. PMID 21486697 DOI: 10.1016/j.bmcl.2011.03.019  1
2011 Cai M, Liu Z, Qu H, Fan H, Zheng Z, Hruby VJ. Utilize conjugated melanotropins for the earlier diagnosis and treatment of melanoma. European Journal of Pharmacology. 660: 188-93. PMID 21315067 DOI: 10.1016/j.ejphar.2011.01.032  1
2011 Hruby VJ, Cai M, Cain J, Nyberg J, Trivedi D. Design of novel melanocortin receptor ligands: multiple receptors, complex pharmacology, the challenge. European Journal of Pharmacology. 660: 88-93. PMID 21208601 DOI: 10.1016/j.ejphar.2010.10.109  1
2010 Mayorov AV, Cai M, Palmer ES, Liu Z, Cain JP, Vagner J, Trivedi D, Hruby VJ. Solid-phase peptide head-to-side chain cyclodimerization: discovery of C(2)-symmetric cyclic lactam hybrid α-melanocyte-stimulating hormone (MSH)/agouti-signaling protein (ASIP) analogues with potent activities at the human melanocortin receptors. Peptides. 31: 1894-905. PMID 20688117 DOI: 10.1016/j.peptides.2010.06.026  1
2010 Doedens L, Opperer F, Cai M, Beck JG, Dedek M, Palmer E, Hruby VJ, Kessler H. Multiple N-methylation of MT-II backbone amide bonds leads to melanocortin receptor subtype hMC1R selectivity: pharmacological and conformational studies. Journal of the American Chemical Society. 132: 8115-28. PMID 20496895 DOI: 10.1021/ja101428m  1
2010 Juni A, Cai M, Stankova M, Waxman AR, Arout C, Klein G, Dahan A, Hruby VJ, Mogil JS, Kest B. Sex-specific mediation of opioid-induced hyperalgesia by the melanocortin-1 receptor. Anesthesiology. 112: 181-8. PMID 19996949 DOI: 10.1097/ALN.0b013e3181c53849  1
2009 Yang Y, Hruby VJ, Chen M, Crasto C, Cai M, Harmon CM. Novel binding motif of ACTH analogues at the melanocortin receptors. Biochemistry. 48: 9775-84. PMID 19743876 DOI: 10.1021/bi900634e  1
2009 Cai M, Nyberg J, Hruby VJ. Melanotropins as drugs for the treatment of obesity and other feeding disorders: potential and problems. Current Topics in Medicinal Chemistry. 9: 554-63. PMID 19689365 DOI: 10.2174/156802609788897817  1
2009 Qu H, Cai M, Mayorov AV, Grieco P, Zingsheim M, Trivedi D, Hruby VJ. Substitution of arginine with proline and proline derivatives in melanocyte-stimulating hormones leads to selectivity for human melanocortin 4 receptor. Journal of Medicinal Chemistry. 52: 3627-35. PMID 19473029 DOI: 10.1021/jm801300c  1
2009 Salamon Z, Fitch J, Cai M, Tumati S, Navratilova E, Tollin G. Plasmon-waveguide resonance studies of ligand binding to integral proteins in membrane fragments derived from bacterial and mammalian cells. Analytical Biochemistry. 387: 95-101. PMID 19454250 DOI: 10.1016/j.ab.2009.01.019  1
2009 Hruby VJ, Cai M, Dedek M, Qu H, Palmer E, Mayorov A, Trivedi D, Tsaprailis G, Yang Y. Peptide and non-peptide mimetics utilize different pathways for signal transduction. Advances in Experimental Medicine and Biology. 611: 305-7. PMID 19400204 DOI: 10.1007/978-0-387-73657-0_137  1
2009 Min BJ, Mayorov AV, Cai M, Palmer E, Hruby VJ. Design and parallel synthesis of new bicyclic small molecules for targeting the melanocortin receptors. Advances in Experimental Medicine and Biology. 611: 187-8. PMID 19400153 DOI: 10.1007/978-0-387-73657-0_86  1
2009 Yang Y, Cai M, Chen M, Qu H, McPherson D, Hruby V, Harmon CM. Key amino acid residues in the melanocortin-4 receptor for nonpeptide THIQ specific binding and signaling. Regulatory Peptides. 155: 46-54. PMID 19303903 DOI: 10.1016/j.regpep.2009.03.006  1
2009 Chen M, Cai M, McPherson D, Hruby V, Harmon CM, Yang Y. Contribution of the transmembrane domain 6 of melanocortin-4 receptor to peptide [Pro5, DNal (2')8]-gamma-MSH selectivity. Biochemical Pharmacology. 77: 114-24. PMID 18930713 DOI: 10.1016/j.bcp.2008.09.023  1
2008 Grieco P, Cai M, Liu L, Mayorov A, Chandler K, Trivedi D, Lin G, Campiglia P, Novellino E, Hruby VJ. Design and microwave-assisted synthesis of novel macrocyclic peptides active at melanocortin receptors: discovery of potent and selective hMC5R receptor antagonists. Journal of Medicinal Chemistry. 51: 2701-7. PMID 18412316 DOI: 10.1021/jm701181n  1
2008 Lee M, Kim A, Conwell IM, Hruby V, Mayorov A, Cai M, Wardlaw SL. Effects of selective modulation of the central melanocortin-3-receptor on food intake and hypothalamic POMC expression. Peptides. 29: 440-7. PMID 18155809 DOI: 10.1016/j.peptides.2007.11.005  1
2008 Mayorov AV, Cai M, Palmer ES, Dedek MM, Cain JP, Van Scoy AR, Tan B, Vagner J, Trivedi D, Hruby VJ. Structure-activity relationships of cyclic lactam analogues of alpha-melanocyte-stimulating hormone (alpha-MSH) targeting the human melanocortin-3 receptor. Journal of Medicinal Chemistry. 51: 187-95. PMID 18088090 DOI: 10.1021/jm070461w  1
2008 Lee YS, Agnes RS, Cain JP, Kulkarni V, Cai M, Salibay C, Ciano K, Petrov R, Mayorov A, Vagner J, Trivedi D, Davis P, Ma SW, Lai J, Porreca F, et al. Opioid and melanocortin receptors: do they have overlapping pharmacophores? Biopolymers. 90: 433-8. PMID 17657709 DOI: 10.1002/bip.20814  1
2008 Hruby VJ, Porreca F, Yamamura HI, Tollin G, Agnes RS, Lee YS, Cai M, Alves I, Cowell S, Varga E, Davis P, Salamon Z, Roeske W, Vanderah T, Lai J. New paradigms and tools in drug design for pain and addiction Drug Addiction: From Basic Research to Therapy. 477-494. DOI: 10.1007/978-0-387-76678-2_28  1
2007 Hruby VJ, Cai M, Cain JP, Mayorov AV, Dedek MM, Trivedi D. Design, synthesis and biological evaluation of ligands selective for the melanocortin-3 receptor. Current Topics in Medicinal Chemistry. 7: 1107-19. PMID 17584128 DOI: 10.2174/156802607780906654  1
2007 Chen M, Cai M, Aprahamian CJ, Georgeson KE, Hruby V, Harmon CM, Yang Y. Contribution of the conserved amino acids of the melanocortin-4 receptor in [corrected] [Nle4,D-Phe7]-alpha-melanocyte-stimulating [corrected] hormone binding and signaling. The Journal of Biological Chemistry. 282: 21712-9. PMID 17545153 DOI: 10.1074/jbc.M702285200  1
2007 Grieco P, Cai M, Han G, Trivedi D, Campiglia P, Novellino E, Hruby VJ. Further structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5. Peptides. 28: 1191-6. PMID 17482720 DOI: 10.1016/j.peptides.2007.02.012  1
2007 Ballet S, Mayorov AV, Cai M, Tymecka D, Chandler KB, Palmer ES, Rompaey KV, Misicka A, Tourwé D, Hruby VJ. Novel selective human melanocortin-3 receptor ligands: use of the 4-amino-1,2,4,5-tetrahydro-2-benzazepin-3-one (Aba) scaffold. Bioorganic & Medicinal Chemistry Letters. 17: 2492-8. PMID 17314042 DOI: 10.1016/j.bmcl.2007.02.020  1
2006 Ying J, Gu X, Cai M, Dedek M, Vagner J, Trivedi DB, Hruby VJ. Design, synthesis, and biological evaluation of new cyclic melanotropin peptide analogues selective for the human melanocortin-4 receptor. Journal of Medicinal Chemistry. 49: 6888-96. PMID 17154518 DOI: 10.1021/jm060768f  1
2006 Cai M, Varga EV, Stankova M, Mayorov A, Perry JW, Yamamura HI, Trivedi D, Hruby VJ. Cell signaling and trafficking of human melanocortin receptors in real time using two-photon fluorescence and confocal laser microscopy: differentiation of agonists and antagonists. Chemical Biology & Drug Design. 68: 183-93. PMID 17105482 DOI: 10.1111/j.1747-0285.2006.00432.x  1
2006 Hruby VJ, Porreca F, Yamamura HI, Tollin G, Agnes RS, Lee YS, Cai M, Alves I, Cowell S, Varga E, Davis P, Salamon Z, Roeske W, Vanderah T, Lai J. New paradigms and tools in drug design for pain and addiction. The Aaps Journal. 8: E450-60. PMID 17025262 DOI: 10.1208/aapsj080353  1
2006 Cain JP, Mayorov AV, Cai M, Wang H, Tan B, Chandler K, Lee Y, Petrov RR, Trivedi D, Hruby VJ. Design, synthesis, and biological evaluation of a new class of small molecule peptide mimetics targeting the melanocortin receptors. Bioorganic & Medicinal Chemistry Letters. 16: 5462-7. PMID 16931008 DOI: 10.1016/j.bmcl.2006.07.015  1
2006 Mayorov AV, Han SY, Cai M, Hammer MR, Trivedi D, Hruby VJ. Effects of macrocycle size and rigidity on melanocortin receptor-1 and -5 selectivity in cyclic lactam alpha-melanocyte-stimulating hormone analogs. Chemical Biology & Drug Design. 67: 329-35. PMID 16784457 DOI: 10.1111/j.1747-0285.2006.00383.x  1
2006 Mayorov AV, Cai M, Chandler KB, Petrov RR, Van Scoy AR, Yu Z, Tanaka DK, Trivedi D, Hruby VJ. Development of cyclic gamma-MSH analogues with selective hMC3R agonist and hMC3R/hMC5R antagonist activities. Journal of Medicinal Chemistry. 49: 1946-52. PMID 16539382 DOI: 10.1021/jm0510326  1
2006 Grieco P, Cai M, Mayorov AV, Trivedi D, Hruby VJ. Structure-activity studies of new melanocortin peptides containing an aromatic amino acid at the N-terminal position. Peptides. 27: 472-81. PMID 16303211 DOI: 10.1016/j.peptides.2005.01.032  1
2005 Cai M, Mayorov AV, Ying J, Stankova M, Trivedi D, Cabello C, Hruby VJ. Design of novel melanotropin agonists and antagonists with high potency and selectivity for human melanocortin receptors. Peptides. 26: 1481-5. PMID 15876475 DOI: 10.1016/j.peptides.2005.03.020  1
2005 Cai M, Mayorov AV, Cabello C, Stankova M, Trivedi D, Hruby VJ. Novel 3D pharmacophore of alpha-MSH/gamma-MSH hybrids leads to selective human MC1R and MC3R analogues. Journal of Medicinal Chemistry. 48: 1839-48. PMID 15771429 DOI: 10.1021/jm049579s  1
2004 Cai M, Stankova M, Pond SJ, Mayorov AV, Perry JW, Yamamura HI, Trivedi D, Hruby VJ. Real time differentiation of G-protein coupled receptor (GPCR) agonist and antagonist by two photon fluorescence laser microscopy. Journal of the American Chemical Society. 126: 7160-1. PMID 15186137 DOI: 10.1021/ja049473m  1
2004 Cai M, Cai C, Mayorov AV, Xiong C, Cabello CM, Soloshonok VA, Swift JR, Trivedi D, Hruby VJ. Biological and conformational study of beta-substituted prolines in MT-II template: steric effects leading to human MC5 receptor selectivity. The Journal of Peptide Research : Official Journal of the American Peptide Society. 63: 116-31. PMID 15009533 DOI: 10.1111/j.1399-3011.2003.00105.x  1
2003 Balse-Srinivasan P, Grieco P, Cai M, Trivedi D, Hruby VJ. Structure-activity relationships of gamma-MSH analogues at the human melanocortin MC3, MC4, and MC5 receptors. Discovery of highly selective hMC3R, hMC4R, and hMC5R analogues. Journal of Medicinal Chemistry. 46: 4965-73. PMID 14584947 DOI: 10.1021/jm030119t  1
2003 Balse-Srinivasan P, Grieco P, Cai M, Trivedi D, Hruby VJ. Structure-activity relationships of novel cyclic alpha-MSH/beta-MSH hybrid analogues that lead to potent and selective ligands for the human MC3R and human MC5R. Journal of Medicinal Chemistry. 46: 3728-33. PMID 12904077 DOI: 10.1021/jm030111j  1
2003 Hruby VJ, Cai M, Grieco P, Han G, Kavarana M, Trivedi D. Exploring the stereostructural requirements of peptide ligands for the melanocortin receptors. Annals of the New York Academy of Sciences. 994: 12-20. PMID 12851293  1
2002 Grieco P, Lavecchia A, Cai M, Trivedi D, Weinberg D, MacNeil T, Van der Ploeg LH, Hruby VJ. Structure-activity studies of the melanocortin peptides: discovery of potent and selective affinity antagonists for the hMC3 and hMC4 receptors. Journal of Medicinal Chemistry. 45: 5287-94. PMID 12431055 DOI: 10.1021/jm0202526  1
2002 Kavarana MJ, Trivedi D, Cai M, Ying J, Hammer M, Cabello C, Grieco P, Han G, Hruby VJ. Novel cyclic templates of alpha-MSH give highly selective and potent antagonists/agonists for human melanocortin-3/4 receptors. Journal of Medicinal Chemistry. 45: 2644-50. PMID 12036373 DOI: 10.1021/jm020021z  1
2002 Wang W, Cai M, Xiong C, Zhang J, Trivedi D, Hruby VJ. Design and synthesis of novel χ2-constrained phenylalanine, naphthylalanine, and tryptophan analogues and their use in biologically active melanotropin peptides Tetrahedron. 58: 7365-7374. DOI: 10.1016/S0040-4020(02)00588-4  1
1997 Tu Y, Cai M, Qu X. The development of transcription regulating of insects antibacterial polypeptide Progress in Biochemistry and Biophysics. 24: 22-26.  1
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