Ruben Vardanyan - Publications

Affiliations: 
2003- University of Arizona, Tucson, AZ 

22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Vardanyan RS, Cain JP, Haghighi SM, Kumirov VK, McIntosh MI, Sandweiss AJ, Porreca F, Hruby VJ. Synthesis and Investigation of Mixed μ-Opioid and δ-Opioid Agonists as Possible Bivalent Ligands for Treatment of Pain. Journal of Heterocyclic Chemistry. 54: 1228-1235. PMID 28819330 DOI: 10.1002/jhet.2696  1
2016 Vardanyan RS, Cain JP, Haghighi SM, Kumirov VK, Mcintosh MI, Sandweiss AJ, Porreca F, Hruby VJ. Synthesis and Investigation of Mixed μ-Opioid and δ-Opioid Agonists as Possible Bivalent Ligands for Treatment of Pain Journal of Heterocyclic Chemistry. DOI: 10.1002/jhet.2696  1
2015 Bird MF, Vardanyan RS, Hruby VJ, Calò G, Guerrini R, Salvadori S, Trapella C, McDonald J, Rowbotham DJ, Lambert DG. Development and characterisation of novel fentanyl-delta opioid receptor antagonist based bivalent ligands. British Journal of Anaesthesia. 114: 646-56. PMID 25680364 DOI: 10.1093/bja/aeu454  1
2014 Vardanyan RS, Hruby VJ. Fentanyl-related compounds and derivatives: current status and future prospects for pharmaceutical applications. Future Medicinal Chemistry. 6: 385-412. PMID 24635521 DOI: 10.4155/fmc.13.215  1
2013 Lee YS, Qu HC, Davis P, Ma SW, Vardanyan R, Lai J, Porreca F, Hruby VJ. Chiral Effect of a Phe Residue in Position 3 of the Dmt(1)-L(or D)-Tic(2) Analogues on Opioid Functional Activities. Acs Medicinal Chemistry Letters. 4: 656-659. PMID 24648867 DOI: 10.1021/ml400115n  1
2013 Podolsky AT, Sandweiss A, Hu J, Bilsky EJ, Cain JP, Kumirov VK, Lee YS, Hruby VJ, Vardanyan RS, Vanderah TW. Novel fentanyl-based dual μ/δ-opioid agonists for the treatment of acute and chronic pain. Life Sciences. 93: 1010-6. PMID 24084045 DOI: 10.1016/j.lfs.2013.09.016  1
2013 Petrov RR, Lee YS, Vardanyan RS, Liu L, Ma SW, Davis P, Lai J, Porreca F, Vanderah TW, Hruby VJ. Effect of anchoring 4-anilidopiperidines to opioid peptides. Bioorganic & Medicinal Chemistry Letters. 23: 3434-7. PMID 23623418 DOI: 10.1016/j.bmcl.2013.03.065  1
2011 Vardanyan RS, Danagulyan GG, Mkrtchyan AD, Hruby VJ. Recyclization reactions of 1-alkylpyrimidinium salts. Heterocyclic Communications. 17: 129-133. PMID 25400328 DOI: 10.1515/hc.2011.025  1
2011 Vardanyan R, Kumirov VK, Nichol GS, Davis P, Liktor-Busa E, Rankin D, Varga E, Vanderah T, Porreca F, Lai J, Hruby VJ. Synthesis and biological evaluation of new opioid agonist and neurokinin-1 antagonist bivalent ligands. Bioorganic & Medicinal Chemistry. 19: 6135-42. PMID 21925887 DOI: 10.1016/j.bmc.2011.08.027  1
2011 Lee YS, Kulkarani V, Cowell SM, Ma SW, Davis P, Hanlon KE, Vanderah TW, Lai J, Porreca F, Vardanyan R, Hruby VJ. Development of potent μ and δ opioid agonists with high lipophilicity. Journal of Medicinal Chemistry. 54: 382-6. PMID 21128594 DOI: 10.1021/jm100982d  1
2011 Vardanyan R, Kumirov VK, Hruby VJ. Improved synthesis of d,l-fluorocitric acid Journal of Fluorine Chemistry. 132: 920-924. DOI: 10.1016/j.jfluchem.2011.07.006  1
2010 Nichol GS, Vardanyan R, Hruby VJ. Synthesis and Crystallographic Study of N'-(1-benzylpiperidin-4-yl)acetohydrazide. Journal of Chemical Crystallography. 40: 961-964. PMID 25505832 DOI: 10.1007/s10870-010-9771-1  1
2010 Nichol GS, Kumirov VK, Vardanyan R, Hruby VJ. Proton sharing and transfer in some zwitterionic compounds based on 4-oxo-4-((1-phenethylpiperidin-4-yl)(phenyl)amino)alcanoic acids. Crystengcomm / Rsc. 12: 3651-3657. PMID 25425961 DOI: 10.1039/B923698H  1
2009 Vardanyan R, Vijay G, Nichol GS, Liu L, Kumarasinghe I, Davis P, Vanderah T, Porreca F, Lai J, Hruby VJ. Synthesis and investigations of double-pharmacophore ligands for treatment of chronic and neuropathic pain. Bioorganic & Medicinal Chemistry. 17: 5044-53. PMID 19540763 DOI: 10.1016/j.bmc.2009.05.065  1
2009 Lee Y, Petrov R, Kulkarni V, Min BJ, Ma SW, Davis P, Oyarzo J, Vanderah T, Lai J, Porreca F, Vardanyan R, Hruby VJ. Development of mu/delta opioid ligands: enkephalin analogues containing 4-anilidopiperidine moiety. Advances in Experimental Medicine and Biology. 611: 517-8. PMID 19400292 DOI: 10.1007/978-0-387-73657-0_225  1
2008 Lee YS, Agnes RS, Cain JP, Kulkarni V, Cai M, Salibay C, Ciano K, Petrov R, Mayorov A, Vagner J, Trivedi D, Davis P, Ma SW, Lai J, Porreca F, ... Vardanyan R, et al. Opioid and melanocortin receptors: do they have overlapping pharmacophores? Biopolymers. 90: 433-8. PMID 17657709 DOI: 10.1002/bip.20814  1
2007 Lee YS, Petrov R, Park CK, Ma SW, Davis P, Lai J, Porreca F, Vardanyan R, Hruby VJ. Development of novel enkephalin analogues that have enhanced opioid activities at both mu and delta opioid receptors. Journal of Medicinal Chemistry. 50: 5528-32. PMID 17927164 DOI: 10.1021/jm061465o  1
2007 Lee YS, Nyberg J, Moye S, Agnes RS, Davis P, Ma SW, Lai J, Porreca F, Vardanyan R, Hruby VJ. Understanding the structural requirements of 4-anilidopiperidine analogues for biological activities at mu and delta opioid receptors. Bioorganic & Medicinal Chemistry Letters. 17: 2161-5. PMID 17329100 DOI: 10.1016/j.bmcl.2007.01.114  1
2006 Petrov RR, Vardanyan RS, Nichol GS, Carducci MD, Ma SW, Lai JY, Hruby VJ. 4-{N-[2-(1,3-Dioxo-1,3-dihydroisoindol-2-yl)-3-phenylpropionyl]anilino}-1-phenethylpiperidinium chloride methanol disolvate. Acta Crystallographica. Section E, Structure Reports Online. 62: o2815-o2816. PMID 17268579 DOI: 10.1107/S1600536806021817  1
2006 Petrov RR, Vardanyan RS, Lee YS, Ma SW, Davis P, Begay LJ, Lai JY, Porreca F, Hruby VJ. Synthesis and evaluation of 3-aminopropionyl substituted fentanyl analogues for opioid activity. Bioorganic & Medicinal Chemistry Letters. 16: 4946-50. PMID 16828552 DOI: 10.1016/j.bmcl.2006.06.040  1
2006 Vardanyan RS, Hruby VJ. Synthesis of Essential Drugs Synthesis of Essential Drugs 1
2005 Vardanyan RS, Hruby VJ, Danagulyan GG, Mkrtchyan AD. Isomerization/Recyclization of some 5-Ethoxycarbonyl-pyrimidines. Journal of Heterocyclic Chemistry. 42: 557-562. PMID 16467919  1
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