Gregory R. Cook, Ph.D. - Publications

1996- Chemistry North Dakota State University, Fargo, ND, United States 
Allylation, Medicinal Chemistry

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Vemula SR, Chhoun MR, Cook GR. Well-Defined Pre-Catalysts in Amide and Ester Bond Activation. Molecules (Basel, Switzerland). 24. PMID 30634382 DOI: 10.3390/molecules24020215  0.64
2018 Vemula SR, Kumar D, Cook GR. Bismuth-Catalyzed Synthesis of 2-Substituted Quinazolinones. Tetrahedron Letters. 59: 3801-3805. PMID 31274936 DOI: 10.1016/j.tetlet.2018.09.014  0.64
2016 Kumar D, Vemula SR, Balasubramanian N, Cook GR. Indium-Mediated Stereoselective Allylation. Accounts of Chemical Research. PMID 27700084 DOI: 10.1021/acs.accounts.6b00362  0.64
2015 Singh RK, Cho K, Padi SK, Yu J, Haldar M, Mandal T, Yan C, Cook G, Guo B, Mallik S, Srivastava DK. Mechanism of N-Acylthiourea-mediated activation of human histone deacetylase 8 (HDAC8) at molecular and cellular levels. The Journal of Biological Chemistry. 290: 6607-19. PMID 25605725 DOI: 10.1074/jbc.M114.600627  0.52
2015 Balasubramanian N, Mandal T, Cook GR. Highly diastereoselective palladium-catalyzed indium-mediated allylation of chiral hydrazones. Organic Letters. 17: 314-7. PMID 25565466 DOI: 10.1021/ol5034207  1
2015 Kumar D, Vemula SR, Cook GR. Highly chemo- and regioselective allylic substitution with tautomerizable heteroarenes Green Chemistry. 17: 4300-4306. DOI: 10.1039/c5gc01028d  1
2015 Vemula SR, Kumar D, Cook GR. N-Boc-glycine-assisted indium-mediated allylation reaction: A sustainable approach Tetrahedron Letters. 56: 3322-3325. DOI: 10.1016/j.tetlet.2015.01.036  1
2014 Singh RK, Suzuki T, Mandal T, Balsubramanian N, Haldar M, Mueller DJ, Strode JA, Cook G, Mallik S, Srivastava DK. Thermodynamics of binding of structurally similar ligands to histone deacetylase 8 sheds light on challenges in the rational design of potent and isozyme-selective inhibitors of the enzyme. Biochemistry. 53: 7445-58. PMID 25407689 DOI: 10.1021/bi500711x  0.52
2013 Singh RK, Lall N, Leedahl TS, McGillivray A, Mandal T, Haldar M, Mallik S, Cook G, Srivastava DK. Kinetic and thermodynamic rationale for suberoylanilide hydroxamic acid being a preferential human histone deacetylase 8 inhibitor as compared to the structurally similar ligand, trichostatin a. Biochemistry. 52: 8139-49. PMID 24079912 DOI: 10.1021/bi400740x  1
2011 Singh RK, Mandal T, Balsubramanian N, Viaene T, Leedahl T, Sule N, Cook G, Srivastava DK. Histone deacetylase activators: N-acetylthioureas serve as highly potent and isozyme selective activators for human histone deacetylase-8 on a fluorescent substrate. Bioorganic & Medicinal Chemistry Letters. 21: 5920-3. PMID 21865040 DOI: 10.1016/j.bmcl.2011.07.080  1
2011 Singh RK, Mandal T, Balasubramanian N, Cook G, Srivastava DK. Coumarin-suberoylanilide hydroxamic acid as a fluorescent probe for determining binding affinities and off-rates of histone deacetylase inhibitors. Analytical Biochemistry. 408: 309-15. PMID 20816742 DOI: 10.1016/j.ab.2010.08.040  1
2009 Samanta D, Kargbo RB, Cook GR. Asymmetric synthesis of aminochromanes via intramolecular indium-mediated allylation of chiral hydrazones. The Journal of Organic Chemistry. 74: 7183-6. PMID 19702255 DOI: 10.1021/jo901195g  1
2008 Hayashi R, Cook GR. Bi(OTf)(3)-Catalyzed 5-Exo-Trig Cyclization via Halide Activation. Tetrahedron Letters. 49: 3888-3890. PMID 19122872 DOI: 10.1016/j.tetlet.2008.04.067  1
2008 Zhang Y, Lukacova V, Bartus V, Nie X, Sun G, Manivannan E, Ghorpade SR, Jin X, Manyem S, Sibi MP, Cook GR, Balaz S. Binding of matrix metalloproteinase inhibitors to extracellular matrix: 3D-QSAR analysis. Chemical Biology & Drug Design. 72: 237-48. PMID 18844670 DOI: 10.1111/j.1747-0285.2008.00710.x  1
2007 Hayashi R, Jin X, Cook GR. Synthesis and evaluation of novel heterocyclic MMP inhibitors. Bioorganic & Medicinal Chemistry Letters. 17: 6864-70. PMID 18029173 DOI: 10.1016/j.bmcl.2007.10.020  1
2007 Kargbo R, Takahashi Y, Bhor S, Cook GR, Lloyd-Jones GC, Shepperson IR. Readily accessible, modular, and tuneable BINOL 3,3'-perfluoroalkylsulfones: highly efficient catalysts for enantioselective in-mediated imine allylation. Journal of the American Chemical Society. 129: 3846-7. PMID 17352482 DOI: 10.1021/ja070742t  1
2007 Hayashi R, Cook GR. Remarkably mild and efficient intramolecular Friedel-Crafts cyclization catalyzed by In(III). Organic Letters. 9: 1311-4. PMID 17346056 DOI: 10.1021/ol070235g  1
2007 Lukacova V, Peng M, Fanucci G, Tandlich R, Hinderliter A, Maity B, Manivannan E, Cook GR, Balaz S. Drug-membrane interactions studied in phospholipid monolayers adsorbed on nonporous alkylated microspheres. Journal of Biomolecular Screening. 12: 186-202. PMID 17218665 DOI: 10.1177/1087057106297063  1
2007 Kargbo RB, Cook GR. Stereoselective indium-mediated allylation reactions Current Organic Chemistry. 11: 1287-1309. DOI: 10.2174/138527207782023139  1
2007 Kaneko M, Hayashi R, Cook GR. Intermolecular Friedel-Crafts reaction catalyzed by InCl3 Tetrahedron Letters. 48: 7085-7087. DOI: 10.1016/j.tetlet.2007.08.011  1
2006 Cook GR, Hayashi R. Atom transfer cyclization catalyzed by InCl3 via halogen activation. Organic Letters. 8: 1045-8. PMID 16524264 DOI: 10.1021/ol052802a  1
2006 Cook GR, Xu W. Tandem palladium-catalyzed allene arylation and oxazoline formation Heterocycles. 67: 215-232. DOI: 10.3987/COM-05-S(T)16  1
2005 Cook GR, Kargbo R, Maity B. Catalytic enantioselective indium-mediated allylation of hydrazones. Organic Letters. 7: 2767-70. PMID 15957942 DOI: 10.1021/ol051160o  1
2005 Cook GR, Saraswathiamma M. Hydrogen-bond directed palladium-catalyzed allylic substitution of cyclic substrates Tetrahedron Letters. 46: 6491-6494. DOI: 10.1016/j.tetlet.2005.07.096  1
2004 Cook GR, Manivannan E, Underdahl T, Lukacova V, Zhang Y, Balaz S. Synthesis and evaluation of novel oxazoline MMP inhibitors. Bioorganic & Medicinal Chemistry Letters. 14: 4935-9. PMID 15341955 DOI: 10.1016/j.bmcl.2004.07.023  1
2004 Cook GR, Sun L. Nitrogen heterocycles via palladium-catalyzed carbocyclization. Formal synthesis of (+)-alpha-allokainic acid. Organic Letters. 6: 2481-4. PMID 15228309 DOI: 10.1021/ol049087+  1
2004 Cook GR, Maity BC, Kargbo R. Highly diastereoselective indium-mediated allylation of chiral hydrazones. Organic Letters. 6: 1741-3. PMID 15151403 DOI: 10.1021/ol0496172  1
2003 Cook GR, Yu H, Sankaranarayanan S, Shanker PS. Hydrogen bond directed highly regioselective palladium-catalyzed allylic substitution. Journal of the American Chemical Society. 125: 5115-20. PMID 12708863 DOI: 10.1021/ja028426w  1
2002 Cook GR, Pararajasingham K. Stereoselective synthesis of D-erythro- and L-threo-sphinganines via palladium-catalyzed equilibration and Suzuki coupling Tetrahedron Letters. 43: 9027-9029. DOI: 10.1016/S0040-4039(02)02309-2  1
2001 Cook GR, Sankaranarayanan S. Palladium-mediated regiodivergent kinetic resolution. Organic Letters. 3: 3531-3. PMID 11678700 DOI: 10.1021/ol016633f  1
2001 Cook GR, Shanker PS. Stereoselective synthesis of MeBmt and methyl (4R,5S)-5-isopropyl-2- phenyloxazoline-4-carboxylate by a Pd-catalyzed equilibration. The Journal of Organic Chemistry. 66: 6818-22. PMID 11578243 DOI: 10.1021/jo015760m  1
2000 Cook GR. Transition metal-mediated kinetic resolution Current Organic Chemistry. 4: 869-885.  1
1999 Cook GR, Shanker PS, Peterson SL. Asymmetric synthesis of the balanol heterocycle via a palladium-mediated epimerization and olefin metathesis. Organic Letters. 1: 615-7. PMID 10823189  1
1999 Sibi MP, Chen JX, Cook GR. Reversal of stereochemistry in diethylzinc addition to aldehydes by a simple change of the backbone substituent in L-serine derived ligands Tetrahedron Letters. 40: 3301-3304. DOI: 10.1016/S0040-4039(99)00480-3  1
1999 Sibi MP, Cook GR, Liu P. Enantioselective reduction of ketones. Examination of bifunctional ligands Tetrahedron Letters. 40: 2477-2480. DOI: 10.1016/S0040-4039(99)00281-6  1
1999 Cook GR, Shanker PS, Pararajasingham K. Palladium-mediated dynamic kinetic resolution: Stereoselective synthesis of vicinal diamines Angewandte Chemie - International Edition. 38: 110-113.  1
1998 Cook GR, Shanker PS. Chloride effect on the palladium-catalyzed allylic substitution vs elimination of cyclic vinyloxazolidinones and oxazolines Tetrahedron Letters. 39: 4991-4994. DOI: 10.1016/S0040-4039(98)00976-9  1
1998 Cook GR, Shanker PS. Palladium-catalyzed formation and stereoselecttve isomerization of 5-vinyloxazolines. Application to the formal synthesis of (S,S)-4-amino-3-hydroxy-5-phenylpentanoic acid Tetrahedron Letters. 39: 3405-3408.  1
1996 Trost BM, Cook GR. An asymmetric synthesis (-)-epibatidine Tetrahedron Letters. 37: 7485-7488. DOI: 10.1016/0040-4039(96)01739-X  1
1994 Cook GR, Beholz LG, Stille JR. Aza-annulation as a route to hydroxylated alkaloid lipids. The synthesis of (±)-prosopinine Tetrahedron Letters. 35: 1669-1672. DOI: 10.1016/0040-4039(94)88315-7  1
1994 Cook GR, Beholz LG, Stille JR. Construction of hydroxylated alkaloids (±)-mannonolactam, (±)-deoxymannojirimycin, and (±)-prosopinine through aza-annulation Journal of Organic Chemistry. 59: 3575-3584.  1
1992 Barta NS, Cook GR, Landis MS, Stille JR. Studies of the regiospecific 3-aza-cope rearrangement promoted by electrophilic reagents Journal of Organic Chemistry. 57: 7188-7194.  1
1992 Cook GR, Barta NS, Stille JR. Lewis acid-promoted 3-aza-Cope rearrangement of N-alkyl-N-allylenamines Journal of Organic Chemistry. 57: 461-467.  1
1991 Cook GR, Stille JR. Preparation and 3-aza-cope rearrangement of N-alkyl-N-allyl enamines Journal of Organic Chemistry. 56: 5578-5583.  1
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