Craig A. Zificsak - Publications

Affiliations: 
2004 University of Minnesota, Twin Cities, Minneapolis, MN 

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Shen Y, Zificsak CA, Shea JE, Lao X, Bollt O, Li X, Lisko JG, Theroff JP, Scaife CL, Ator MA, Ruggeri BA, Dorsey BD, Kuwada SK. Design, synthesis, and biological evaluation of sulfonyl acrylonitriles as novel inhibitors of cancer metastasis and spread. Journal of Medicinal Chemistry. 58: 1140-58. PMID 25581261 DOI: 10.1021/jm501437v  1
2012 Zificsak CA, Shen Y, Lisko JG, Theroff JP, Lao X, Bollt O, Li X, Dorsey BD, Kuwada SK. Synthesis and biological evaluation of sulfonyl acrylonitriles as novel inhibitors to peritoneal carcinomatosis. Bioorganic & Medicinal Chemistry Letters. 22: 1850-3. PMID 22326395 DOI: 10.1016/j.bmcl.2012.01.085  1
2012 Zificsak CA, Gingrich DE, Breslin HJ, Dunn DD, Milkiewicz KL, Theroff JP, Thieu TV, Underiner TL, Weinberg LR, Aimone LD, Albom MS, Mason JL, Saville L, Husten J, Angeles TS, et al. Optimization of a novel kinase inhibitor scaffold for the dual inhibition of JAK2 and FAK kinases. Bioorganic & Medicinal Chemistry Letters. 22: 133-7. PMID 22169263 DOI: 10.1016/j.bmcl.2011.11.049  1
2012 Mesaros EF, Thieu TV, Wells GJ, Zificsak CA, Wagner JC, Breslin HJ, Tripathy R, Diebold JL, McHugh RJ, Wohler AT, Quail MR, Wan W, Lu L, Huang Z, Albom MS, et al. Strategies to mitigate the bioactivation of 2-anilino-7-aryl-pyrrolo[2,1-f][1,2,4]triazines: identification of orally bioavailable, efficacious ALK inhibitors. Journal of Medicinal Chemistry. 55: 115-25. PMID 22141319 DOI: 10.1021/jm2010767  1
2011 Zificsak CA, Theroff JP, Aimone LD, Angeles TS, Albom MS, Cheng M, Mesaros EF, Ott GR, Quail MR, Underiner TL, Wan W, Dorsey BD. Methanesulfonamido-cyclohexylamine derivatives of 2,4-diaminopyrimidine as potent ALK inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 3877-80. PMID 21632243 DOI: 10.1016/j.bmcl.2011.05.040  1
2011 Zificsak CA, Theroff JP, Aimone LD, Albom MS, Angeles TS, Brown RA, Galinis D, Grobelny JV, Herbertz T, Husten J, Kocsis LS, LoSardo C, Miknyoczki SJ, Murthy S, Rolon-Steele D, et al. 2,4-Diaminopyrimidine inhibitors of c-Met kinase bearing benzoxazepine anilines. Bioorganic & Medicinal Chemistry Letters. 21: 660-3. PMID 21190849 DOI: 10.1016/j.bmcl.2010.12.013  1
2011 Weinberg LR, Albom MS, Angeles TS, Husten J, Lisko JG, McHugh RJ, Milkiewicz KL, Murthy S, Ott GR, Theroff JP, Tripathy R, Underiner TL, Zificsak CA, Dorsey BD. Fused bicyclic derivatives of 2,4-diaminopyrimidine as c-Met inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 164-7. PMID 21123062 DOI: 10.1016/j.bmcl.2010.11.045  1
2010 Milkiewicz KL, Weinberg LR, Albom MS, Angeles TS, Cheng M, Ghose AK, Roemmele RC, Theroff JP, Underiner TL, Zificsak CA, Dorsey BD. Synthesis and structure-activity relationships of 1,2,3,4-tetrahydropyrido[2,3-b]pyrazines as potent and selective inhibitors of the anaplastic lymphoma kinase. Bioorganic & Medicinal Chemistry. 18: 4351-62. PMID 20483621 DOI: 10.1016/j.bmc.2010.04.087  1
2007 Ko C, Hsung RP, Al-Rashid ZF, Feltenberger JB, Lu T, Yang JH, Wei Y, Zificsak CA. A stereoselective intramolecular halo-etherification of chiral enamides in the synthesis of halogenated cyclic ethers. Organic Letters. 9: 4459-62. PMID 17910461 DOI: 10.1021/ol701768n  1
2007 Berry CR, Zificsak CA, Gibbs AC, Hlasta DJ. Cycloaddition reactions of thiazolium azomethine ylides: application to pyrrolo[2,1-b]thiazoles. Organic Letters. 9: 4099-102. PMID 17854191 DOI: 10.1021/ol071229n  1
2005 Sydorenko N, Zificsak CA, Gerasyuto AI, Hsung RP. Total syntheses of enantiomerically enriched R-(+)- and S-(-)-deplancheine. Organic & Biomolecular Chemistry. 3: 2140-4. PMID 15917902 DOI: 10.1039/b503862f  1
2005 Zificsak CA, Hlasta DJ. Synthesis of 2-(α-substituted-amidoalkyl)-imidazoles Tetrahedron Letters. 46: 4789-4792. DOI: 10.1016/j.tetlet.2005.05.026  1
2004 Zificsak CA, Hlasta DJ. Current methods for the synthesis of 2-substituted azoles Tetrahedron. 60: 8991-9016. DOI: 10.1016/j.tet.2004.07.016  1
2003 Luo S, Zificsak CA, Hsung RP. Intramolecular formal aza-[3 + 3] cycloaddition approach to indoloquinolizidine alkaloids. A stereoselective total synthesis of (+/-)-tangutorine. Organic Letters. 5: 4709-12. PMID 14627421 DOI: 10.1021/ol030114q  1
2003 Mulder JA, Kurtz KC, Hsung RP, Coverdale H, Frederick MO, Shen L, Zificsak CA. Highly stereoselective synthesis of novel alpha-haloenamides via a mild and efficient hydrohalogenation of ynamides. Organic Letters. 5: 1547-50. PMID 12713320 DOI: 10.1021/ol0300266  1
2003 Shen HC, Wang J, Cole KP, McLaughlin MJ, Morgan CD, Douglas CJ, Hsung RP, Coverdale HA, Gerasyuto AI, Hahn JM, Liu J, Sklenicka HM, Wei LL, Zehnder LR, Zificsak CA. A formal [3 + 3] cycloaddition reaction. Improved reactivity using alpha,beta-unsaturated iminium salts and evidence for reversibility of 6pi-electron electrocyclic ring closure of 1-oxatrienes. The Journal of Organic Chemistry. 68: 1729-35. PMID 12608785 DOI: 10.1021/jo020688t  1
2003 Czerwinski KM, Zificsak CA, Stevens J, Oberbeck M, Randlett C, King M, Mennen S. An improved synthesis of canthin-6-one Synthetic Communications. 33: 1225-1231. DOI: 10.1081/SCC-120017199  1
2002 Mulder JA, Hsung RP, Frederick MO, Tracey MR, Zificsak CA. The first stereoselective Ficini-Claisen rearrangement using chiral ynamides. Organic Letters. 4: 1383-6. PMID 11950368 DOI: 10.1021/ol020037j  1
2001 Zehnder LR, Wei LL, Hsung RP, Cole KP, McLaughlin MJ, Shen HC, Sklenicka HM, Wang J, Zificsak CA. Stereoselective trans- and cis-dihydroxylations of 2H-pyranyl and dihydropyridinyl heterocycles synthesized from formal [3 + 3]-cycloaddition reactions of alpha,beta-unsaturated iminium ions with 1,3-dicarbonyl equivalents. Organic Letters. 3: 2141-4. PMID 11440564 DOI: 10.1021/ol010034r  1
2001 Zificsak CA, Mulder JA, Hsung RP, Rameshkumar C, Wei LL. Recent advances in the chemistry of ynamines and ynamides Tetrahedron. 57: 7575-7606. DOI: 10.1016/S0040-4020(01)00681-0  1
2001 Wei LL, Mulder JA, Xiong H, Zificsak CA, Douglas CJ, Hsung RP. Efficient preparations of novel ynamides and allenamides Tetrahedron. 57: 459-466.  1
1999 Degen SJ, Mueller KL, Shen HC, Mulder JA, Golding GM, Wei LL, Zificsak CA, Neeno-Eckwall A, Hsung RP. Synthesis of dihydroxanthone derivatives and evaluation of their inhibitory activity against acetylcholinesterase: unique structural analogs of tacrine based on the BCD-ring of arisugacin. Bioorganic & Medicinal Chemistry Letters. 9: 973-8. PMID 10230623 DOI: 10.1016/S0960-894X(99)00115-8  1
1999 Hsung RP, Zificsak CA, Wei LL, Zehnder LR, Park F, Kim M, Tran TTT. A rare acid-promoted elimination of O-methyl oximes: A practical synthesis of 3-cyano-4-benzopyrones Journal of Organic Chemistry. 64: 8736-8740. DOI: 10.1021/jo991031j  1
1999 Hsung RP, Zificsak CA, Wei LL, Douglas CJ, Xiong H, Mulder JA. Lewis acid promoted hetero [2 + 2] cycloaddition reactions of aldehydes with 10-propynyl-9(10h)-acridone. A highly stereoselective synthesis of acrylic acid derivatives and 1,3-dienes using an electron deficient variant of ynamine Organic Letters. 1: 1237-1240.  1
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