Margie Mattmann - Publications

2010 University of Wisconsin, Madison, Madison, WI 
synthesis of biologically active molecules

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Eibergen NR, Moore JD, Mattmann ME, Blackwell HE. Potent and Selective Modulation of the RhlR Quorum Sensing Receptor by Using Non-native Ligands: An Emerging Target for Virulence Control in Pseudomonas aeruginosa. Chembiochem : a European Journal of Chemical Biology. 16: 2348-56. PMID 26460240 DOI: 10.1002/cbic.201500357  1
2014 Jalan-Sakrikar N, Field JR, Klar R, Mattmann ME, Gregory KJ, Zamorano R, Engers DW, Bollinger SR, Weaver CD, Days EL, Lewis LM, Utley TJ, Hurtado M, Rigault D, Acher F, et al. Identification of positive allosteric modulators VU0155094 (ML397) and VU0422288 (ML396) reveals new insights into the biology of metabotropic glutamate receptor 7. Acs Chemical Neuroscience. 5: 1221-37. PMID 25225882 DOI: 10.1021/cn500153z  1
2013 Blobaum AL, Bridges TM, Byers FW, Turlington ML, Mattmann ME, Morrison RD, Mackie C, Lavreysen H, Bartolomé JM, Macdonald GJ, Steckler T, Jones CK, Niswender CM, Conn PJ, Lindsley CW, et al. Heterotropic activation of the midazolam hydroxylase activity of CYP3A by a positive allosteric modulator of mGlu5: in vitro to in vivo translation and potential impact on clinically relevant drug-drug interactions. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 2066-75. PMID 24003250 DOI: 10.1124/dmd.113.052662  1
2013 Limpert AS, Mattmann ME, Cosford ND. Recent progress in the discovery of small molecules for the treatment of amyotrophic lateral sclerosis (ALS). Beilstein Journal of Organic Chemistry. 9: 717-32. PMID 23766784 DOI: 10.3762/bjoc.9.82  1
2013 Yu H, Lin Z, Mattmann ME, Zou B, Terrenoire C, Zhang H, Wu M, McManus OB, Kass RS, Lindsley CW, Hopkins CR, Li M. Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels. Proceedings of the National Academy of Sciences of the United States of America. 110: 8732-7. PMID 23650380 DOI: 10.1073/pnas.1300684110  1
2013 Melancon BJ, Poslusney MS, Gentry PR, Tarr JC, Sheffler DJ, Mattmann ME, Bridges TM, Utley TJ, Daniels JS, Niswender CM, Conn PJ, Lindsley CW, Wood MR. Isatin replacements applied to the highly selective, muscarinic M1 PAM ML137: continued optimization of an MLPCN probe molecule. Bioorganic & Medicinal Chemistry Letters. 23: 412-6. PMID 23237839 DOI: 10.1016/j.bmcl.2012.11.092  1
2012 Mattmann ME, Yu H, Lin Z, Xu K, Huang X, Long S, Wu M, McManus OB, Engers DW, Le UM, Li M, Lindsley CW, Hopkins CR. Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator. Bioorganic & Medicinal Chemistry Letters. 22: 5936-41. PMID 22910039 DOI: 10.1016/j.bmcl.2012.07.060  1
2012 Melancon BJ, Utley TJ, Sevel C, Mattmann ME, Cheung YY, Bridges TM, Morrison RD, Sheffler DJ, Niswender CM, Daniels JS, Conn PJ, Lindsley CW, Wood MR. Development of novel M1 antagonist scaffolds through the continued optimization of the MLPCN probe ML012. Bioorganic & Medicinal Chemistry Letters. 22: 5035-40. PMID 22749871 DOI: 10.1016/j.bmcl.2012.06.018  1
2011 Lindemann A, Pessi G, Schaefer AL, Mattmann ME, Christensen QH, Kessler A, Hennecke H, Blackwell HE, Greenberg EP, Harwood CS. Isovaleryl-homoserine lactone, an unusual branched-chain quorum-sensing signal from the soybean symbiont Bradyrhizobium japonicum. Proceedings of the National Academy of Sciences of the United States of America. 108: 16765-70. PMID 21949379 DOI: 10.1073/pnas.1114125108  1
2011 Mattmann ME, Stoops SL, Lindsley CW. Inhibition of Akt with small molecules and biologics: historical perspective and current status of the patent landscape. Expert Opinion On Therapeutic Patents. 21: 1309-38. PMID 21635152 DOI: 10.1517/13543776.2011.587959  1
2011 Mattmann ME, Shipway PM, Heth NJ, Blackwell HE. Potent and selective synthetic modulators of a quorum sensing repressor in Pseudomonas aeruginosa identified from second-generation libraries of N-acylated L-homoserine lactones. Chembiochem : a European Journal of Chemical Biology. 12: 942-9. PMID 21365734 DOI: 10.1002/cbic.201000708  1
2010 Mattmann ME, Blackwell HE. Small molecules that modulate quorum sensing and control virulence in Pseudomonas aeruginosa. The Journal of Organic Chemistry. 75: 6737-46. PMID 20672805 DOI: 10.1021/jo101237e  1
2008 Geske GD, Mattmann ME, Blackwell HE. Evaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulators. Bioorganic & Medicinal Chemistry Letters. 18: 5978-81. PMID 18760602 DOI: 10.1016/j.bmcl.2008.07.089  1
2008 Geske GD, O'Neill JC, Miller DM, Wezeman RJ, Mattmann ME, Lin Q, Blackwell HE. Comparative analyses of N-acylated homoserine lactones reveal unique structural features that dictate their ability to activate or inhibit quorum sensing. Chembiochem : a European Journal of Chemical Biology. 9: 389-400. PMID 18224645 DOI: 10.1002/cbic.200700551  1
2008 Mattmann ME, Geske GD, Worzalla GA, Chandler JR, Sappington KJ, Greenberg EP, Blackwell HE. Synthetic ligands that activate and inhibit a quorum-sensing regulator in Pseudomonas aeruginosa. Bioorganic & Medicinal Chemistry Letters. 18: 3072-5. PMID 18083553 DOI: 10.1016/j.bmcl.2007.11.095  1
2007 Geske GD, O'Neill JC, Miller DM, Mattmann ME, Blackwell HE. Modulation of bacterial quorum sensing with synthetic ligands: systematic evaluation of N-acylated homoserine lactones in multiple species and new insights into their mechanisms of action. Journal of the American Chemical Society. 129: 13613-25. PMID 17927181 DOI: 10.1021/ja074135h  1
2007 Chan YY, Bian HS, Tan TM, Mattmann ME, Geske GD, Igarashi J, Hatano T, Suga H, Blackwell HE, Chua KL. Control of quorum sensing by a Burkholderia pseudomallei multidrug efflux pump. Journal of Bacteriology. 189: 4320-4. PMID 17384185 DOI: 10.1128/JB.00003-07  1
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