Sean M. Smith - Publications

Affiliations: 
2012 The University of Nebraska - Lincoln, Lincoln, NE 

40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Zhao Z, Harrison ST, Schubert JW, Sanders JM, Polsky-Fisher S, Zhang NR, McLoughlin D, Gibson CR, Robinson RG, Sachs NA, Kandebo M, Yao L, Smith SM, Hutson PH, Wolkenberg SE, et al. Synthesis and optimization of N-heterocyclic pyridinones as catechol-O-methyltransferase (COMT) inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 27133481 DOI: 10.1016/j.bmcl.2016.03.095  0.56
2016 Vardigan JD, Lange HS, Tye SJ, Fox SV, Smith SM, Uslaner JM. Behavioral and qEEG effects of the PDE10A inhibitor THPP-1 in a novel rhesus model of antipsychotic activity. Psychopharmacology. PMID 27117142 DOI: 10.1007/s00213-016-4290-1  0.56
2015 Raheem IT, Schreier JD, Fuerst J, Gantert L, Hostetler ED, Huszar S, Joshi A, Kandebo M, Kim SH, Li J, Ma B, McGaughey G, Sharma S, Shipe WD, Uslaner J, ... ... Smith SM, et al. Discovery of pyrazolopyrimidine phosphodiesterase 10A inhibitors for the treatment of schizophrenia. Bioorganic & Medicinal Chemistry Letters. PMID 26602277 DOI: 10.1016/j.bmcl.2015.11.013  0.56
2015 Hostetler ED, Fan H, Joshi AD, Zeng Z, Eng W, Gantert L, Holahan M, Meng X, Miller P, O'Malley S, Purcell M, Riffel K, Salinas C, Williams M, Ma B, ... ... Smith SM, et al. Preclinical Characterization of the Phosphodiesterase 10A PET Tracer [(11)C]MK-8193. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 26596571 DOI: 10.1007/s11307-015-0910-0  0.56
2015 Shipe WD, Sharik SS, Barrow JC, McGaughey GB, Theberge CR, Uslaner JM, Yan Y, Renger JJ, Smith SM, Coleman PJ, Cox CD. Discovery and Optimization of a Series of Pyrimidine-Based Phosphodiesterase 10A (PDE10A) Inhibitors through Fragment Screening, Structure-Based Design, and Parallel Synthesis. Journal of Medicinal Chemistry. PMID 26378882 DOI: 10.1021/acs.jmedchem.5b00983  0.56
2015 Cox CD, Hostetler ED, Flores BA, Evelhoch JL, Fan H, Gantert L, Holahan M, Eng W, Joshi A, McGaughey G, Meng X, Purcell M, Raheem IT, Riffel K, Yan Y, ... ... Smith SM, et al. Discovery of [(11)C]MK-8193 as a PET tracer to measure target engagement of phosphodiesterase 10A (PDE10A) inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 26077491 DOI: 10.1016/j.bmcl.2015.05.080  0.56
2015 Gentzel RC, Toolan D, Roberts R, Koser AJ, Kandebo M, Hershey J, Renger JJ, Uslaner J, Smith SM. The PDE10A inhibitor MP-10 and haloperidol produce distinct gene expression profiles in the striatum and influence cataleptic behavior in rodents. Neuropharmacology. PMID 26044638 DOI: 10.1016/j.neuropharm.2015.05.024  0.56
2015 Hoang GL, Yang ZD, Smith SM, Pal R, Miska JL, Pérez DE, Pelter LS, Zeng XC, Takacs JM. Enantioselective desymmetrization via carbonyl-directed catalytic asymmetric hydroboration and Suzuki-Miyaura cross-coupling. Organic Letters. 17: 940-3. PMID 25642639 DOI: 10.1021/ol503764d  0.56
2014 Ramirez AD, Smith SM. Regulation of dopamine signaling in the striatum by phosphodiesterase inhibitors: novel therapeutics to treat neurological and psychiatric disorders. Central Nervous System Agents in Medicinal Chemistry. 14: 72-82. PMID 25540976  0.56
2014 Nawrocki AR, Rodriguez CG, Toolan DM, Price O, Henry M, Forrest G, Szeto D, Keohane CA, Pan Y, Smith KM, Raheem IT, Cox CD, Hwa J, Renger JJ, Smith SM. Genetic deletion and pharmacological inhibition of phosphodiesterase 10A protects mice from diet-induced obesity and insulin resistance. Diabetes. 63: 300-11. PMID 24101672 DOI: 10.2337/db13-0247  0.56
2013 Smith SM, Uslaner JM, Cox CD, Huszar SL, Cannon CE, Vardigan JD, Eddins D, Toolan DM, Kandebo M, Yao L, Raheem IT, Schreier JD, Breslin MJ, Coleman PJ, Renger JJ. The novel phosphodiesterase 10A inhibitor THPP-1 has antipsychotic-like effects in rat and improves cognition in rat and rhesus monkey. Neuropharmacology. 64: 215-23. PMID 22750078 DOI: 10.1016/j.neuropharm.2012.06.013  0.56
2012 Smith SM, Hoang GL, Pal R, Bani Khaled MO, Pelter LS, Zeng XC, Takacs JM. γ-Selective directed catalytic asymmetric hydroboration of 1,1-disubstituted alkenes. Chemical Communications (Cambridge, England). 48: 12180-2. PMID 23145431 DOI: 10.1039/c2cc36199j  0.56
2012 Raheem IT, Breslin MJ, Fandozzi C, Fuerst J, Hill N, Huszar S, Kandebo M, Kim SH, Ma B, McGaughey G, Renger JJ, Schreier JD, Sharma S, Smith S, Uslaner J, et al. Discovery of tetrahydropyridopyrimidine phosphodiesterase 10A inhibitors for the treatment of schizophrenia. Bioorganic & Medicinal Chemistry Letters. 22: 5903-8. PMID 22892116 DOI: 10.1016/j.bmcl.2012.07.072  0.56
2012 Robinson RG, Smith SM, Wolkenberg SE, Kandebo M, Yao L, Gibson CR, Harrison ST, Polsky-Fisher S, Barrow JC, Manley PJ, Mulhearn JJ, Nanda KK, Schubert JW, Trotter BW, Zhao Z, et al. Characterization of non-nitrocatechol pan and isoform specific catechol-O-methyltransferase inhibitors and substrates. Acs Chemical Neuroscience. 3: 129-40. PMID 22860182 DOI: 10.1021/cn200109w  0.56
2012 Uslaner JM, Smith SM, Huszar SL, Pachmerhiwala R, Hinchliffe RM, Vardigan JD, Nguyen SJ, Surles NO, Yao L, Barrow JC, Uebele VN, Renger JJ, Clark J, Hutson PH. T-type calcium channel antagonism produces antipsychotic-like effects and reduces stimulant-induced glutamate release in the nucleus accumbens of rats. Neuropharmacology. 62: 1413-21. PMID 21110986 DOI: 10.1016/j.neuropharm.2010.11.015  0.56
2011 Smith SM, Uteuliyev M, Takacs JM. Catalytic asymmetric hydroboration of β,γ-unsaturated Weinreb amides: striking influence of the borane. Chemical Communications (Cambridge, England). 47: 7812-4. PMID 21637887 DOI: 10.1039/c1cc11746g  0.56
2011 Hutson PH, Finger EN, Magliaro BC, Smith SM, Converso A, Sanderson PE, Mullins D, Hyde LA, Eschle BK, Turnbull Z, Sloan H, Guzzi M, Zhang X, Wang A, Rindgen D, et al. The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) enhances synaptic plasticity and cognitive function in rodents. Neuropharmacology. 61: 665-76. PMID 21619887 DOI: 10.1016/j.neuropharm.2011.05.009  0.56
2010 Smith SM, Takacs JM. Remarkable levels of enantioswitching in catalytic asymmetric hydroboration. Organic Letters. 12: 4612-5. PMID 20863120 DOI: 10.1021/ol101932q  0.56
2010 Smith SM, Uslaner JM, Hutson PH. The Therapeutic Potential of D-Amino Acid Oxidase (DAAO) Inhibitors. The Open Medicinal Chemistry Journal. 4: 3-9. PMID 20648222 DOI: 10.2174/1874104501004020003  0.56
2010 Smith SM, Takacs JM. Amide-directed catalytic asymmetric hydroboration of trisubstituted alkenes. Journal of the American Chemical Society. 132: 1740-1. PMID 20092272 DOI: 10.1021/ja908257x  0.56
2009 Uslaner JM, Smith SM, Huszar SL, Pachmerhiwala R, Hinchliffe RM, Vardigan JD, Hutson PH. Combined administration of an mGlu2/3 receptor agonist and a 5-HT 2A receptor antagonist markedly attenuate the psychomotor-activating and neurochemical effects of psychostimulants. Psychopharmacology. 206: 641-51. PMID 19707745 DOI: 10.1007/s00213-009-1644-y  0.56
2009 Smith SM, Uslaner JM, Yao L, Mullins CM, Surles NO, Huszar SL, McNaughton CH, Pascarella DM, Kandebo M, Hinchliffe RM, Sparey T, Brandon NJ, Jones B, Venkatraman S, Young MB, et al. The behavioral and neurochemical effects of a novel D-amino acid oxidase inhibitor compound 8 [4H-thieno [3,2-b]pyrrole-5-carboxylic acid] and D-serine. The Journal of Pharmacology and Experimental Therapeutics. 328: 921-30. PMID 19088300 DOI: 10.1124/jpet.108.147884  0.56
2009 Ciarmela P, Wiater E, Smith SM, Vale W. Presence, actions, and regulation of myostatin in rat uterus and myometrial cells. Endocrinology. 150: 906-14. PMID 18845635 DOI: 10.1210/en.2008-0880  0.56
2008 Smith SM, Thacker NC, Takacs JM. Efficient amide-directed catalytic asymmetric hydroboration. Journal of the American Chemical Society. 130: 3734-5. PMID 18311977 DOI: 10.1021/ja710492q  0.56
2007 Perrin MH, Grace CR, Digruccio MR, Fischer WH, Maji SK, Cantle JP, Smith S, Manning G, Vale WW, Riek R. Distinct structural and functional roles of conserved residues in the first extracellular domain of receptors for corticotropin-releasing factor and related G-protein-coupled receptors. The Journal of Biological Chemistry. 282: 37529-36. PMID 17940290 DOI: 10.1074/jbc.M703748200  0.56
2007 Jenkins TJ, Guan B, Dai M, Li G, Lightburn TE, Huang S, Freeze BS, Burdi DF, Jacutin-Porte S, Bennett R, Chen W, Minor C, Ghosh S, Blackburn C, Gigstad KM, ... ... Smith S, et al. Design, synthesis, and evaluation of naphthalene-sulfonamide antagonists of human CCR8. Journal of Medicinal Chemistry. 50: 566-84. PMID 17266208 DOI: 10.1021/jm061118e  0.56
2006 Smith SM, Vale WW. The role of the hypothalamic-pituitary-adrenal axis in neuroendocrine responses to stress. Dialogues in Clinical Neuroscience. 8: 383-95. PMID 17290797  0.56
2006 Chen A, Brar B, Choi CS, Rousso D, Vaughan J, Kuperman Y, Kim SN, Donaldson C, Smith SM, Jamieson P, Li C, Nagy TR, Shulman GI, Lee KF, Vale W. Urocortin 2 modulates glucose utilization and insulin sensitivity in skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. 103: 16580-5. PMID 17050686 DOI: 10.1073/pnas.0607337103  0.56
2006 Chen A, Zorrilla E, Smith S, Rousso D, Levy C, Vaughan J, Donaldson C, Roberts A, Lee KF, Vale W. Urocortin 2-deficient mice exhibit gender-specific alterations in circadian hypothalamus-pituitary-adrenal axis and depressive-like behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5500-10. PMID 16707802 DOI: 10.1523/JNEUROSCI.3955-05.2006  0.56
2006 Ghosh S, Elder A, Guo J, Mani U, Patane M, Carson K, Ye Q, Bennett R, Chi S, Jenkins T, Guan B, Kolbeck R, Smith S, Zhang C, LaRosa G, et al. Design, synthesis, and progress toward optimization of potent small molecule antagonists of CC chemokine receptor 8 (CCR8). Journal of Medicinal Chemistry. 49: 2669-72. PMID 16640325 DOI: 10.1021/jm050965z  0.56
2006 Smith SM, Vaughan JM, Donaldson CJ, Fernandez RE, Li C, Chen A, Vale WW. Cocaine- and amphetamine-regulated transcript is localized in pituitary lactotropes and is regulated during lactation. Endocrinology. 147: 1213-23. PMID 16339196 DOI: 10.1210/en.2005-1392  0.56
2004 Smith SM, Vaughan JM, Donaldson CJ, Rivier J, Li C, Chen A, Vale WW. Cocaine- and amphetamine-regulated transcript activates the hypothalamic-pituitary-adrenal axis through a corticotropin-releasing factor receptor-dependent mechanism. Endocrinology. 145: 5202-9. PMID 15271883 DOI: 10.1210/en.2004-0708  0.56
2003 Yunker WK, Smith S, Graves C, Davis PJ, Unniappan S, Rivier JE, Peter RE, Chang JP. Endogenous hypothalamic somatostatins differentially regulate growth hormone secretion from goldfish pituitary somatotropes in vitro Endocrinology. 144: 4031-4041. PMID 12933677 DOI: 10.1210/en.2003-0439  0.56
2003 Smith SM, Ramirez VD. DARP-36aa selectively promotes survival and morphological development of cultured mesencephalic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 252-9. PMID 12514222  0.56
2002 Smith S, Ramirez VD. Direct visualization of internalization and intracellular trafficking of dopamine-releasing protein-36aa. Neuroendocrinology. 75: 98-112. PMID 11867938 DOI: 10.1159/000048226  0.56
1999 Smith S, Ramirez VD. Cellular localization of dopamine-releasing protein (DARP) in rat C6 glioma and primary mesencephalic cell cultures. Brain Research. 843: 95-104. PMID 10528115 DOI: 10.1016/S0006-8993(99)01895-8  0.56
1999 Langell MA, Anderson MD, Carson GA, Peng L, Smith S. Valence-band electronic structure of Co3O4 epitaxy on CoO(100) Physical Review B - Condensed Matter and Materials Physics. 59: 4791-4798.  0.56
1999 Langell MA, Carson GA, Smith S, Peng L, Nassir MH. The valence electronic structure of 00304: Is it a charge-transfer insulator? Materials Research Society Symposium - Proceedings. 547: 255-260.  0.56
1996 Barrington JW, Lindsay P, James D, Smith S, Roberts A. Selenium deficiency and miscarriage: a possible link? British Journal of Obstetrics and Gynaecology. 103: 130-2. PMID 8616128  0.56
1994 Smith SM, Posada JL, Young VY. Preparation of sulfate-free lead-silver-sulfide from aqueous solutions Journal of Materials Science Letters. 13: 813-816. DOI: 10.1007/BF00271329  0.56
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