Henning D. Mootz, Ph.D. - Publications

2001-2003 Princeton University, Princeton, NJ 
 2010- Westfälische Wilhelms-Universität Münster, Münster, Nordrhein-Westfalen, Germany 

106 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Mayerthaler F, Feldberg AL, Alfermann J, Sun X, Steinchen W, Yang H, Mootz HD. Intermediary conformations linked to the directionality of the aminoacylation pathway of nonribosomal peptide synthetases. Rsc Chemical Biology. 2: 843-854. PMID 34458813 DOI: 10.1039/d0cb00220h  1
2021 Bhagawati M, Arroum T, Webeling N, Montoro AG, Mootz HD, Busch KB. The receptor subunit Tom20 is dynamically associated with the TOM complex in mitochondria of human cells. Molecular Biology of the Cell. mbcE21010042. PMID 34347503 DOI: 10.1091/mbc.E21-01-0042  1
2021 Reichert D, Mootz HD, Rentmeister A. Light-control of cap methylation and mRNA translation genetic code expansion of Ecm1. Chemical Science. 12: 4383-4388. PMID 34163701 DOI: 10.1039/d1sc00159k  0.01
2021 Yusenko MV, Trentmann A, Casolari DA, Abdel Ghani L, Lenz M, Horn M, Dörner W, Klempnauer S, Mootz HD, Arteaga MF, Mikesch JH, Andrea RJ, Gonda TJ, Müller-Tidow C, Schmidt TJ, et al. C/EBPβ is a MYB- and p300-cooperating pro-leukemogenic factor and promising drug target in acute myeloid leukemia. Oncogene. PMID 33958723 DOI: 10.1038/s41388-021-01800-x  1
2021 Palei S, Mootz HD. Semisynthetic head-to-tail cyclized peptides obtained by combining protein -splicing and intramolecular expressed protein ligation. Chemical Communications (Cambridge, England). 57: 4194-4197. PMID 33908454 DOI: 10.1039/d1cc00449b  1
2021 Reille-Seroussi M, Meyer-Ahrens P, Aust A, Feldberg AL, Mootz HD. Genetic encoding and enzymatic deprotection of a latent thiol side chain to enable new protein bioconjugation applications. Angewandte Chemie (International Ed. in English). PMID 33844389 DOI: 10.1002/anie.202102343  1
2020 Aparicio Pelaz D, Yerkesh Z, Kirchgäßner S, Mahler H, Kharchenko V, Azhibek D, Jaremko M, Mootz HD, Jaremko Ł, Schwarzer D, Fischle W. Examining histone modification crosstalk using immobilized libraries established from ligation-ready nucleosomes. Chemical Science. 11: 9218-9225. PMID 34123170 DOI: 10.1039/d0sc03407j  1
2020 Dehling E, Rüschenbaum J, Diecker J, Dörner W, Mootz HD. Photo-crosslink analysis in nonribosomal peptide synthetases reveals aberrant gel migration of branched crosslink isomers and spatial proximity between non-neighboring domains. Chemical Science. 11: 8945-8954. PMID 34123148 DOI: 10.1039/d0sc01969k  1
2020 Kötter A, Mootz HD, Heuer A. Insights into the Microscopic Structure of RNF4-SIM-SUMO Complexes from MD Simulations. Biophysical Journal. 119: 1558-1567. PMID 32976759 DOI: 10.1016/j.bpj.2020.09.003  1
2020 Hoffmann S, Terhorst TME, Singh RK, Kümmel D, Pietrokovski S, Mootz HD. Biochemical and structural characterization of an unusual and naturally split class 3 intein. Chembiochem : a European Journal of Chemical Biology. PMID 32813312 DOI: 10.1002/Cbic.202000509  1
2020 Brüninghoff K, Aust A, Taupitz KF, Wulff S, Dörner W, Mootz HD. Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking. Acs Chemical Biology. PMID 32786267 DOI: 10.1021/Acschembio.0C00609  1
2020 Bhagawati M, Hoffmann S, Höffgen KS, Piehler J, Busch KB, Mootz HD. In Cellulo Protein Semi-Synthesis from Endogenous and Exogenous Fragments Using the Ultra-Fast Split Gp41-1 Intein. Angewandte Chemie (International Ed. in English). PMID 32777124 DOI: 10.1002/Anie.202006822  1
2020 Cibis H, Biyanee A, Dörner W, Mootz HD, Klempnauer KH. Characterization of the zinc finger proteins ZMYM2 and ZMYM4 as novel B-MYB binding proteins. Scientific Reports. 10: 8390. PMID 32439918 DOI: 10.1038/S41598-020-65443-W  1
2020 Pelaz DA, Yerkesh Z, Kirchgäßner S, Mahler H, Kharchenko V, Azhibek D, Jaremko M, Mootz HD, Jaremko Ł, Schwarzer D, Fischle W. Examining histone modification crosstalk using immobilized libraries established from ligation-ready nucleosomes Chemical Science. 11: 9218-9225. DOI: 10.1039/D0Sc03407J  1
2020 Dehling E, Rüschenbaum J, Diecker J, Dörner W, Mootz HD. Photo-crosslink analysis in nonribosomal peptide synthetases reveals aberrant gel migration of branched crosslink isomers and spatial proximity between non-neighboring domains Chemical Science. 11: 8945-8954. DOI: 10.1039/D0Sc01969K  1
2019 Mootz HD, Jedlitzke B, Yilmaz Z, Dörner W. Photobodies: Light-activatable single-domain antibody fragments. Angewandte Chemie (International Ed. in English). PMID 31755215 DOI: 10.1002/Anie.201912286  1
2019 Bhagawati M, Terhorst TME, Füsser F, Hoffmann S, Pasch T, Pietrokovski S, Mootz HD. A mesophilic cysteine-less split intein for protein -splicing applications under oxidizing conditions. Proceedings of the National Academy of Sciences of the United States of America. 116: 22164-22172. PMID 31611397 DOI: 10.1073/Pnas.1909825116  1
2019 Kotter A, Mootz HD, Heuer A. Standard binding free energy of a SIM SUMO complex. Journal of Chemical Theory and Computation. PMID 31525924 DOI: 10.1021/Acs.Jctc.9B00428  1
2019 Reille-Seroussi M, Mayer SV, Dörner W, Lang K, Mootz HD. Expanding the genetic code with a lysine derivative bearing an enzymatically removable phenylacetyl group. Chemical Communications (Cambridge, England). PMID 30945708 DOI: 10.1039/C9Cc00475K  1
2019 Degen A, Mayerthaler F, Mootz HD, Di Ventura B. Context-dependent activity of A domains in the tyrocidine synthetase. Scientific Reports. 9: 5119. PMID 30914767 DOI: 10.1038/S41598-019-41492-8  1
2019 Friedel K, Popp MA, Matern JCJ, Gazdag EM, Thiel IV, Volkmann G, Blankenfeldt W, Mootz HD. A functional interplay between intein and extein sequences in protein splicing compensates for the essential block B histidine. Chemical Science. 10: 239-251. PMID 30713635 DOI: 10.2210/Pdb6Frg/Pdb  1
2019 Böcker JK, Dörner W, Mootz HD. Light-control of the ultra-fast Gp41-1 split intein with preserved stability of a genetically encoded photo-caged amino acid in bacterial cells. Chemical Communications (Cambridge, England). 55: 1287-1290. PMID 30633261 DOI: 10.1039/C8Cc09204D  1
2018 Böcker JK, Dörner W, Mootz HD. Rational Design of an Improved Photo-Activatable Intein for the Production of Head-To-Tail Cyclized Peptides. Biological Chemistry. PMID 30403651 DOI: 10.1515/Hsz-2018-0367  1
2018 Hagmann V, Sommer S, Fabian P, Bierlmeier J, van Treel N, Mootz HD, Schwarzer D, Azevedo JE, Dodt G. Chemically monoubiquitinated PEX5 binds to the components of the peroxisomal docking and export machinery. Scientific Reports. 8: 16014. PMID 30375424 DOI: 10.1038/S41598-018-34200-5  1
2018 Grill D, Matos ALL, de Vries WC, Kudruk S, Heflik M, Dörner W, Mootz HD, Jan Ravoo B, Galla HJ, Gerke V. Bridging of membrane surfaces by annexin A2. Scientific Reports. 8: 14662. PMID 30279443 DOI: 10.1038/S41598-018-33044-3  1
2018 Di Ventura B, Mootz HD. Switchable inteins for conditional protein splicing. Biological Chemistry. PMID 30226200 DOI: 10.1515/Hsz-2018-0309  1
2018 Palei S, Becher KS, Nienberg C, Jose J, Mootz HD. Bacterial Cell Surface Display of Semi-Synthetic Cyclic Peptides. Chembiochem : a European Journal of Chemical Biology. PMID 30216604 DOI: 10.1002/Cbic.201800552  1
2018 Matern JCJ, Friedel K, Binschik J, Becher KS, Yilmaz Z, Mootz HD. Altered Coordination of Individual Catalytic Steps in Different and Evolved Inteins Reveals Kinetic Plasticity of the Protein Splicing Pathway. Journal of the American Chemical Society. PMID 30111090 DOI: 10.1021/Jacs.8B04794  1
2018 Pirzer T, Becher KS, Rieker M, Meckel T, Mootz HD, Kolmar H. Generation of potent anti-HER1/2 immunotoxins by protein ligation using split inteins. Acs Chemical Biology. PMID 29920062 DOI: 10.1021/Acschembio.8B00222  1
2017 Moll JM, Wehmöller M, Frank NC, Homey L, Baran P, Garbers C, Lamertz L, Axelrod JH, Galun E, Mootz HD, Scheller J. Split(2) protein-ligation generates active IL-6-type Hyper-cytokines from inactive precursors. Acs Synthetic Biology. PMID 29136368 DOI: 10.1021/Acssynbio.7B00208  0.01
2017 Kost LJ, Mootz HD. A FRET sensor to monitor bivalent SUMO-SIM interactions in SUMO chain binding. Chembiochem : a European Journal of Chemical Biology. PMID 29120074 DOI: 10.1002/Cbic.201700507  0.01
2017 Alfermann J, Sun X, Mayerthaler F, Morrell TE, Dehling E, Volkmann G, Komatsuzaki T, Yang H, Mootz HD. FRET monitoring of a nonribosomal peptide synthetase. Nature Chemical Biology. PMID 28759017 DOI: 10.1038/Nchembio.2435  1
2017 Falkenberg KD, Jakobs A, Matern JC, Dörner W, Uttarkar S, Trentmann A, Steinmann S, Coulibaly A, Schomburg C, Mootz HD, Schmidt TJ, Klempnauer KH. Withaferin A, a natural compound with anti-tumor activity, is a potent inhibitor of transcription factor C/EBPβ. Biochimica Et Biophysica Acta. PMID 28476645 DOI: 10.1016/J.Bbamcr.2017.05.003  1
2017 Bachmann AL, Mootz HD. N-terminal chemical protein labeling using the naturally split GOS-TerL intein. Journal of Peptide Science : An Official Publication of the European Peptide Society. PMID 28332258 DOI: 10.1002/Psc.2996  1
2017 Taupitz KF, Dörner W, Mootz HD. Covalent capturing of transient SUMO-SIM interactions using unnatural amino acid mutagenesis and photocrosslinking. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28121373 DOI: 10.1002/Chem.201605619  1
2017 Palei S, Mootz HD. Preparation of Semisynthetic Peptides Macrocycles Using Split Inteins. Methods in Molecular Biology (Clifton, N.J.). 1495: 77-92. PMID 27714611 DOI: 10.1007/978-1-4939-6451-2_6  1
2016 Dehling E, Volkmann G, Matern JC, Dörner W, Alfermann J, Diecker J, Mootz HD. Mapping of the communication-mediating interface in nonribosomal peptide synthetases using a genetically encoded photocrosslinker supports an upside-down helix-hand motif. Journal of Molecular Biology. PMID 27647046 DOI: 10.1016/J.Jmb.2016.09.007  1
2016 Neugebauer M, Böcker JK, Matern JC, Pietrokovski S, Mootz HD. Development of a screening system for inteins active in protein splicing based on intein insertion into the LacZα-peptide. Biological Chemistry. PMID 27632429 DOI: 10.1515/Hsz-2016-0229  1
2016 Nienberg C, Retterath A, Becher KS, Saenger T, Mootz HD, Jose J. Site-Specific Labeling of Protein Kinase CK2: Combining Surface Display and Click Chemistry for Drug Discovery Applications. Pharmaceuticals (Basel, Switzerland). 9. PMID 27355959 DOI: 10.3390/Ph9030036  1
2015 Palei S, Mootz HD. Cyclic peptides made by linking synthetic and genetically encoded fragments. Chembiochem : a European Journal of Chemical Biology. PMID 26691013 DOI: 10.1002/Cbic.201500673  1
2015 Bachmann AL, Mootz HD. An Unprecedented Combination of Serine and Cysteine Nucleophiles in a Split Intein with an Atypical Split Site. The Journal of Biological Chemistry. PMID 26453311 DOI: 10.1074/Jbc.M115.677237  1
2015 Fischle W, Mootz HD, Schwarzer D. Synthetic histone code. Current Opinion in Chemical Biology. 28: 131-40. PMID 26256563 DOI: 10.1016/J.Cbpa.2015.07.005  1
2015 Sommer S, Ritterhoff T, Melchior F, Mootz HD. A stable chemical SUMO1-Ubc9 conjugate specifically binds as a thioester mimic to the RanBP2-E3 ligase complex. Chembiochem : a European Journal of Chemical Biology. 16: 1183-9. PMID 25917782 DOI: 10.1002/Cbic.201500011  1
2015 Fischle W, Schwarzer D, Mootz HD. Chemical biology: Chromatin chemistry goes cellular. Nature Chemistry. 7: 371-3. PMID 25901809 DOI: 10.1038/Nchem.2249  1
2015 Bachmann AL, Matern JC, Schütz V, Mootz HD. Chemical-tag labeling of proteins using fully recombinant split inteins. Methods in Molecular Biology (Clifton, N.J.). 1266: 145-59. PMID 25560073 DOI: 10.1007/978-1-4939-2272-7_10  1
2015 Matern JC, Bachmann AL, Thiel IV, Volkmann G, Wasmuth A, Binschik J, Mootz HD. Ligation of synthetic peptides to proteins using semisynthetic protein trans-splicing. Methods in Molecular Biology (Clifton, N.J.). 1266: 129-43. PMID 25560072 DOI: 10.1007/978-1-4939-2272-7_9  1
2015 Böcker JK, Friedel K, Matern JC, Bachmann AL, Mootz HD. Generation of a genetically encoded, photoactivatable intein for the controlled production of cyclic peptides. Angewandte Chemie (International Ed. in English). 54: 2116-20. PMID 25557882 DOI: 10.1002/Anie.201409848  1
2015 Fischle W, Mootz HD, Schwarzer D. Synthetic histone code Current Opinion in Chemical Biology. 28: 131-140. DOI: 10.1016/j.cbpa.2015.07.005  1
2014 Sun X, Li H, Alfermann J, Mootz HD, Yang H. Kinetics profiling of gramicidin S synthetase A, a member of nonribosomal peptide synthetases. Biochemistry. 53: 7983-9. PMID 25437123 DOI: 10.1021/Bi501156M  1
2014 Schütz V, Mootz HD. Click-tag and amine-tag: chemical tag approaches for efficient protein labeling in vitro and on live cells using the naturally split Npu DnaE intein. Angewandte Chemie (International Ed. in English). 53: 4113-7. PMID 24615830 DOI: 10.1002/Anie.201309396  1
2014 Thiel IV, Volkmann G, Pietrokovski S, Mootz HD. An atypical naturally split intein engineered for highly efficient protein labeling. Angewandte Chemie (International Ed. in English). 53: 1306-10. PMID 24382817 DOI: 10.1002/Anie.201307969  1
2014 van Treel ND, Mootz HD. SUMOylated RanGAP1 prepared by click chemistry. Journal of Peptide Science : An Official Publication of the European Peptide Society. 20: 121-7. PMID 24338848 DOI: 10.1002/Psc.2591  1
2013 Zettler J, Eppmann S, Busche A, Dikovskaya D, Dötsch V, Mootz HD, Sonntag T. SPLICEFINDER - a fast and easy screening method for active protein trans-splicing positions. Plos One. 8: e72925. PMID 24023792 DOI: 10.1371/Journal.Pone.0072925  1
2013 Kawai S, Cooper D, Landes C, Mootz HD, Yang H, Komatsuzaki T. Numerical construction of estimators for single-molecule fluorescence measurements. The Journal of Physical Chemistry. B. 117: 8061-74. PMID 23777303 DOI: 10.1021/Jp402328M  1
2013 Wasmuth A, Ludwig C, Mootz HD. Structure-activity studies on the upstream splice junction of a semisynthetic intein. Bioorganic & Medicinal Chemistry. 21: 3495-503. PMID 23618706 DOI: 10.1016/J.Bmc.2013.03.065  1
2013 Sommer S, Weikart ND, Linne U, Mootz HD. Covalent inhibition of SUMO and ubiquitin-specific cysteine proteases by an in situ thiol-alkyne addition. Bioorganic & Medicinal Chemistry. 21: 2511-7. PMID 23535560 DOI: 10.1016/J.Bmc.2013.02.039  1
2013 Binschik J, Mootz HD. Chemical bypass of intein-catalyzed N-S acyl shift in protein splicing. Angewandte Chemie (International Ed. in English). 52: 4260-4. PMID 23468274 DOI: 10.1002/Anie.201208863  1
2013 Volkmann G, Mootz HD. Recent progress in intein research: from mechanism to directed evolution and applications. Cellular and Molecular Life Sciences : Cmls. 70: 1185-206. PMID 22926412 DOI: 10.1007/S00018-012-1120-4  1
2013 Dresselhaus T, Weikart ND, Mootz HD, Waller MP. Naturally and synthetically linked lys48 diubiquitin: A QM/MM study Rsc Advances. 3: 16122-16129. DOI: 10.1039/C3Ra42649A  1
2012 Carvajal-Vallejos P, Pallissé R, Mootz HD, Schmidt SR. Unprecedented rates and efficiencies revealed for new natural split inteins from metagenomic sources. The Journal of Biological Chemistry. 287: 28686-96. PMID 22753413 DOI: 10.1074/Jbc.M112.372680  1
2012 Schwarzer D, Ludwig C, Thiel IV, Mootz HD. Probing intein-catalyzed thioester formation by unnatural amino acid substitutions in the active site. Biochemistry. 51: 233-42. PMID 22182201 DOI: 10.1021/Bi2014823  1
2012 Weikart ND, Sommer S, Mootz HD. Click synthesis of ubiquitin dimer analogs to interrogate linkage-specific UBA domain binding. Chemical Communications (Cambridge, England). 48: 296-8. PMID 22095407 DOI: 10.1039/C1Cc15834A  1
2011 Sommer S, Weikart ND, Brockmeyer A, Janning P, Mootz HD. Expanded click conjugation of recombinant proteins with ubiquitin-like modifiers reveals altered substrate preference of SUMO2-modified Ubc9. Angewandte Chemie (International Ed. in English). 50: 9888-92. PMID 21898723 DOI: 10.1002/Anie.201102531  1
2011 Appleby-Tagoe JH, Thiel IV, Wang Y, Wang Y, Mootz HD, Liu XQ. Highly efficient and more general cis- and trans-splicing inteins through sequential directed evolution. The Journal of Biological Chemistry. 286: 34440-7. PMID 21832069 DOI: 10.1074/Jbc.M111.277350  1
2011 Dhar T, Kurpiers T, Mootz HD. Extending the scope of site-specific cysteine bioconjugation by appending a prelabeled cysteine tag to proteins using protein trans-splicing. Methods in Molecular Biology (Clifton, N.J.). 751: 131-42. PMID 21674329 DOI: 10.1007/978-1-61779-151-2_9  1
2011 Sonntag T, Mootz HD. An intein-cassette integration approach used for the generation of a split TEV protease activated by conditional protein splicing. Molecular Biosystems. 7: 2031-9. PMID 21487580 DOI: 10.1039/C1Mb05025G  1
2011 Binschik J, Zettler J, Mootz HD. Photocontrol of protein activity mediated by the cleavage reaction of a split intein. Angewandte Chemie (International Ed. in English). 50: 3249-52. PMID 21384476 DOI: 10.1002/Anie.201007078  1
2011 Dhar T, Mootz HD. Modification of transmembrane and GPI-anchored proteins on living cells by efficient protein trans-splicing using the Npu DnaE intein. Chemical Communications (Cambridge, England). 47: 3063-5. PMID 21234473 DOI: 10.1039/C0Cc04172F  1
2010 Garbe D, Thiel IV, Mootz HD. Protein trans-splicing on an M13 bacteriophage: towards directed evolution of a semisynthetic split intein by phage display. Journal of Peptide Science : An Official Publication of the European Peptide Society. 16: 575-81. PMID 20862725 DOI: 10.1002/Psc.1243  1
2010 Weikart ND, Mootz HD. Generation of site-specific and enzymatically stable conjugates of recombinant proteins with ubiquitin-like modifiers by the Cu(I)-catalyzed azide-alkyne cycloaddition. Chembiochem : a European Journal of Chemical Biology. 11: 774-7. PMID 20209558 DOI: 10.1002/Cbic.200900738  1
2010 Zettler J, Mootz HD. Biochemical evidence for conformational changes in the cross-talk between adenylation and peptidyl-carrier protein domains of nonribosomal peptide synthetases. The Febs Journal. 277: 1159-71. PMID 20121951 DOI: 10.1111/J.1742-4658.2009.07551.X  1
2009 Mootz HD. Split inteins as versatile tools for protein semisynthesis. Chembiochem : a European Journal of Chemical Biology. 10: 2579-89. PMID 19708049 DOI: 10.1002/Cbic.200900370  1
2009 Ludwig C, Schwarzer D, Zettler J, Garbe D, Janning P, Czeslik C, Mootz HD. Semisynthesis of proteins using split inteins. Methods in Enzymology. 462: 77-96. PMID 19632470 DOI: 10.1016/S0076-6879(09)62004-8  1
2009 Brenzel S, Cebi M, Reiss P, Koert U, Mootz HD. Expanding the scope of protein trans-splicing to fragment ligation of an integral membrane protein: towards modulation of porin-based ion channels by chemical modification. Chembiochem : a European Journal of Chemical Biology. 10: 983-6. PMID 19322843 DOI: 10.1002/Cbic.200900039  1
2009 Zettler J, Schütz V, Mootz HD. The naturally split Npu DnaE intein exhibits an extraordinarily high rate in the protein trans-splicing reaction. Febs Letters. 583: 909-14. PMID 19302791 DOI: 10.1016/J.Febslet.2009.02.003  1
2009 Kurpiers T, Mootz HD. Bioorthogonal ligation in the spotlight. Angewandte Chemie (International Ed. in English). 48: 1729-31. PMID 19148914 DOI: 10.1002/Anie.200805454  1
2008 Rosenfeldt G, Viana RM, Mootz HD, von Arnim AG, Batschauer A. Chemically induced and light-independent cryptochrome photoreceptor activation. Molecular Plant. 1: 4-14. PMID 20031911 DOI: 10.1093/Mp/Ssm002  1
2008 Kurpiers T, Mootz HD. Site-specific chemical modification of proteins with a prelabelled cysteine tag using the artificially split Mxe GyrA intein. Chembiochem : a European Journal of Chemical Biology. 9: 2317-25. PMID 18756552 DOI: 10.1002/Cbic.200800319  1
2008 Ludwig C, Schwarzer D, Mootz HD. Interaction studies and alanine scanning analysis of a semi-synthetic split intein reveal thiazoline ring formation from an intermediate of the protein splicing reaction. The Journal of Biological Chemistry. 283: 25264-72. PMID 18625708 DOI: 10.1074/Jbc.M802972200  1
2007 Kurpiers T, Mootz HD. Regioselective cysteine bioconjugation by appending a labeled cystein tag to a protein by using protein splicing in trans. Angewandte Chemie (International Ed. in English). 46: 5234-7. PMID 17538921 DOI: 10.1002/Anie.200700719  1
2007 Mootz HD. Posttranslational processing: Protein splicing by inteins - Goldmine for protein chemical applications | Posttranslationale Prozessierung: Protein-spleißen Durch Inteine Fund - Grube für Proteinchemische Anwendungen Biospektrum. 13: 165-167.  1
2007 Schwarzer D, Mootz HD, Micura R. Biochemistry and molecular biology 2006 | Biochemie und Molekularbiologie 2006 Nachrichten Aus Der Chemie. 55: 276-284.  1
2006 Ludwig C, Pfeiff M, Linne U, Mootz HD. Ligation of a synthetic peptide to the N terminus of a recombinant protein using semisynthetic protein trans-splicing. Angewandte Chemie (International Ed. in English). 45: 5218-21. PMID 16823791 DOI: 10.1002/Anie.200600570  1
2006 Brenzel S, Kurpiers T, Mootz HD. Engineering artificially split inteins for applications in protein chemistry: biochemical characterization of the split Ssp DnaB intein and comparison to the split Sce VMA intein. Biochemistry. 45: 1571-8. PMID 16460004 DOI: 10.1021/Bi051697+  1
2006 Roelfes G, Mootz HD. Probing the molecular basis of protein function through chemistry. Chembiochem : a European Journal of Chemical Biology. 7: 545-9. PMID 16453350 DOI: 10.1002/Cbic.200500547  1
2005 Brenzel S, Mootz HD. Design of an intein that can be inhibited with a small molecule ligand. Journal of the American Chemical Society. 127: 4176-7. PMID 15783192 DOI: 10.1021/Ja043501J  1
2004 Mootz HD, Blum ES, Muir TW. Activation of an autoregulated protein kinase by conditional protein splicing. Angewandte Chemie (International Ed. in English). 43: 5189-92. PMID 15455415 DOI: 10.1002/Anie.200460941  1
2004 Gruenewald S, Mootz HD, Stehmeier P, Stachelhaus T. In vivo production of artificial nonribosomal peptide products in the heterologous host Escherichia coli. Applied and Environmental Microbiology. 70: 3282-91. PMID 15184122 DOI: 10.1128/Aem.70.6.3282-3291.2004  1
2003 Mootz HD, Blum ES, Tyszkiewicz AB, Muir TW. Conditional protein splicing: a new tool to control protein structure and function in vitro and in vivo. Journal of the American Chemical Society. 125: 10561-9. PMID 12940738 DOI: 10.1021/Ja0362813  1
2003 Linne U, Stein DB, Mootz HD, Marahiel MA. Systematic and quantitative analysis of protein-protein recognition between nonribosomal peptide synthetases investigated in the tyrocidine biosynthetic template. Biochemistry. 42: 5114-24. PMID 12718555 DOI: 10.1021/Bi034223O  1
2002 Schwarzer D, Mootz HD, Linne U, Marahiel MA. Regeneration of misprimed nonribosomal peptide synthetases by type II thioesterases. Proceedings of the National Academy of Sciences of the United States of America. 99: 14083-8. PMID 12384573 DOI: 10.1073/Pnas.212382199  1
2002 Mootz HD, Schwarzer D, Marahiel MA. Ways of assembling complex natural products on modular nonribosomal peptide synthetases. Chembiochem : a European Journal of Chemical Biology. 3: 490-504. PMID 12325005 DOI: 10.1002/1439-7633(20020603)3:6<490::Aid-Cbic490>3.0.Co;2-N  1
2002 Mootz HD, Kessler N, Linne U, Eppelmann K, Schwarzer D, Marahiel MA. Decreasing the ring size of a cyclic nonribosomal peptide antibiotic by in-frame module deletion in the biosynthetic genes. Journal of the American Chemical Society. 124: 10980-1. PMID 12224936 DOI: 10.1021/Ja027276M  1
2002 Mootz HD, Muir TW. Protein splicing triggered by a small molecule. Journal of the American Chemical Society. 124: 9044-5. PMID 12148996 DOI: 10.1021/Ja026769O  1
2002 Mootz HD, Schörgendorfer K, Marahiel MA. Functional characterization of 4'-phosphopantetheinyl transferase genes of bacterial and fungal origin by complementation of Saccharomyces cerevisiae lys5. Fems Microbiology Letters. 213: 51-7. PMID 12127488 DOI: 10.1111/J.1574-6968.2002.Tb11285.X  1
2001 Schwarzer D, Mootz HD, Marahiel MA. Exploring the impact of different thioesterase domains for the design of hybrid peptide synthetases. Chemistry & Biology. 8: 997-1010. PMID 11590023 DOI: 10.1016/S1074-5521(01)00068-0  1
2001 Mootz HD, Finking R, Marahiel MA. 4'-phosphopantetheine transfer in primary and secondary metabolism of Bacillus subtilis. The Journal of Biological Chemistry. 276: 37289-98. PMID 11489886 DOI: 10.1074/Jbc.M103556200  1
2001 Döring V, Mootz HD, Nangle LA, Hendrickson TL, de Crécy-Lagard V, Schimmel P, Marlière P. Enlarging the amino acid set of Escherichia coli by infiltration of the valine coding pathway. Science (New York, N.Y.). 292: 501-4. PMID 11313495 DOI: 10.1126/Science.1057718  1
2000 Trauger JW, Kohli RM, Mootz HD, Marahiel MA, Walsh CT. Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase. Nature. 407: 215-8. PMID 11001063 DOI: 10.1038/35025116  1
2000 Mootz HD, Schwarzer D, Marahiel MA. Construction of hybrid peptide synthetases by module and domain fusions. Proceedings of the National Academy of Sciences of the United States of America. 97: 5848-53. PMID 10811885 DOI: 10.1073/Pnas.100075897  1
1999 Mootz HD, Marahiel MA. Design and application of multimodular peptide synthetases. Current Opinion in Biotechnology. 10: 341-8. PMID 10449311 DOI: 10.1016/S0958-1669(99)80062-7  1
1999 Stachelhaus T, Mootz HD, Marahiel MA. The specificity-conferring code of adenylation domains in nonribosomal peptide synthetases. Chemistry & Biology. 6: 493-505. PMID 10421756 DOI: 10.1016/S1074-5521(99)80082-9  1
1998 Stachelhaus T, Mootz HD, Bergendahl V, Marahiel MA. Peptide bond formation in nonribosomal peptide biosynthesis. Catalytic role of the condensation domain. The Journal of Biological Chemistry. 273: 22773-81. PMID 9712910 DOI: 10.1074/Jbc.273.35.22773  1
1997 Marahiel MA, Stachelhaus T, Mootz HD. Modular Peptide Synthetases Involved in Nonribosomal Peptide Synthesis. Chemical Reviews. 97: 2651-2674. PMID 11851476 DOI: 10.1021/Cr960029E  1
1997 Mootz HD, Marahiel MA. Biosynthetic systems for nonribosomal peptide antibiotic assembly. Current Opinion in Chemical Biology. 1: 543-51. PMID 9667890 DOI: 10.1016/S1367-5931(97)80051-8  1
1997 Mootz HD, Marahiel MA. The tyrocidine biosynthesis operon of Bacillus brevis: complete nucleotide sequence and biochemical characterization of functional internal adenylation domains. Journal of Bacteriology. 179: 6843-50. PMID 9352938 DOI: 10.1128/Jb.179.21.6843-6850.1997  1
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