Harold Kohn - Publications

Affiliations: 
1973-1999 Chemistry University of Houston, Houston, TX, United States 
 1999- Medicinal Chemistry University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
biological mechanisms of therapeutic agents
Website:
http://www.chem.unc.edu/research/index.html?display=organic&content=kohn

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Year Citation  Score
2014 Lee H, Park KD, Torregrosa R, Yang XF, Dustrude ET, Wang Y, Wilson SM, Barbosa C, Xiao Y, Cummins TR, Khanna R, Kohn H. Substituted N-(biphenyl-4'-yl)methyl (R)-2-acetamido-3-methoxypropionamides: potent anticonvulsants that affect frequency (use) dependence and slow inactivation of sodium channels. Journal of Medicinal Chemistry. 57: 6165-82. PMID 25004277 DOI: 10.1021/Jm500707R  0.406
2013 Lee H, Gold AS, Yang XF, Khanna R, Kohn H. Benzyloxybenzylammonium chlorides: Simple amine salts that display anticonvulsant activity. Bioorganic & Medicinal Chemistry. 21: 7655-62. PMID 24238903 DOI: 10.1016/J.Bmc.2013.10.031  0.328
2013 Park KD, Yang XF, Lee H, Dustrude ET, Wang Y, Khanna R, Kohn H. Discovery of lacosamide affinity bait agents that exhibit potent voltage-gated sodium channel blocking properties. Acs Chemical Neuroscience. 4: 463-74. PMID 23509982 DOI: 10.1021/Cn300188H  0.363
2012 King AM, Yang XF, Wang Y, Dustrude ET, Barbosa C, Due MR, Piekarz AD, Wilson SM, White FA, Salomé C, Cummins TR, Khanna R, Kohn H. Identification of the benzyloxyphenyl pharmacophore: a structural unit that promotes sodium channel slow inactivation. Acs Chemical Neuroscience. 3: 1037-49. PMID 23259039 DOI: 10.1021/Cn300129D  0.601
2012 Baruah PK, Dinsmore J, King AM, Salomé C, De Ryck M, Kaminski R, Provins L, Kohn H. Synthesis, anticonvulsant activity, and neuropathic pain-attenuating activity of N-benzyl 2-amino-2-(hetero)aromatic acetamides. Bioorganic & Medicinal Chemistry. 20: 3551-64. PMID 22546207 DOI: 10.1016/J.Bmc.2012.04.002  0.635
2011 King AM, De Ryck M, Kaminski R, Valade A, Stables JP, Kohn H. Defining the structural parameters that confer anticonvulsant activity by the site-by-site modification of (R)-N'-benzyl 2-amino-3-methylbutanamide. Journal of Medicinal Chemistry. 54: 6432-42. PMID 21861466 DOI: 10.1021/Jm200760A  0.665
2011 King AM, Salomé C, Salomé-Grosjean E, De Ryck M, Kaminski R, Valade A, Stables JP, Kohn H. Primary amino acid derivatives: substitution of the 4'-N'-benzylamide site in (R)-N'-benzyl 2-amino-3-methylbutanamide, (R)-N'-benzyl 2-amino-3,3-dimethylbutanamide, and (R)-N'-benzyl 2-amino-3-methoxypropionamide provides potent anticonvulsants with pain-attenuating properties. Journal of Medicinal Chemistry. 54: 6417-31. PMID 21861463 DOI: 10.1021/Jm200759T  0.659
2011 Wang Y, Wilson SM, Brittain JM, Ripsch MS, Salomé C, Park KD, White FA, Khanna R, Kohn H. Merging Structural Motifs of Functionalized Amino Acids and α-Aminoamides Results in Novel Anticonvulsant Compounds with Significant Effects on Slow and Fast Inactivation of Voltage-gated Sodium Channels and in the Treatment of Neuropathic Pain. Acs Chemical Neuroscience. 2: 317-322. PMID 21765969 DOI: 10.1021/Cn200024Z  0.35
2011 Park KD, Kim D, Reamtong O, Eyers C, Gaskell SJ, Liu R, Kohn H. Identification of a lacosamide binding protein using an affinity bait and chemical reporter strategy: 14-3-3 ζ. Journal of the American Chemical Society. 133: 11320-30. PMID 21692503 DOI: 10.1021/Ja2034156  0.35
2011 King AM, Salomé C, Dinsmore J, Salomé-Grosjean E, De Ryck M, Kaminski R, Valade A, Kohn H. Primary amino acid derivatives: compounds with anticonvulsant and neuropathic pain protection activities. Journal of Medicinal Chemistry. 54: 4815-30. PMID 21639114 DOI: 10.1021/Jm2004305  0.665
2011 Wang Y, Park KD, Salome C, Wilson SM, Stables JP, Liu R, Khanna R, Kohn H. Development and characterization of novel derivatives of the antiepileptic drug lacosamide that exhibit far greater enhancement in slow inactivation of voltage-gated sodium channels. Acs Chemical Neuroscience. 2: 90-106. PMID 21532923 DOI: 10.1021/Cn100089B  0.368
2010 Morieux P, Salomé C, Park KD, Stables JP, Kohn H. The structure-activity relationship of the 3-oxy site in the anticonvulsant (R)-N-benzyl 2-acetamido-3-methoxypropionamide. Journal of Medicinal Chemistry. 53: 5716-26. PMID 20614888 DOI: 10.1021/Jm100508M  0.77
2010 Park KD, Stables JP, Liu R, Kohn H. Proteomic searches comparing two (R)-lacosamide affinity baits: An electrophilic arylisothiocyanate and a photoactivated arylazide group. Organic & Biomolecular Chemistry. 8: 2803-13. PMID 20405068 DOI: 10.1039/C000987C  0.37
2010 Salomé C, Salomé-Grosjean E, Stables JP, Kohn H. Merging the structural motifs of functionalized amino acids and alpha-aminoamides: compounds with significant anticonvulsant activities. Journal of Medicinal Chemistry. 53: 3756-71. PMID 20394379 DOI: 10.1021/Jm100185C  0.366
2010 Salomé C, Salomé-Grosjean E, Park KD, Morieux P, Swendiman R, DeMarco E, Stables JP, Kohn H. Synthesis and anticonvulsant activities of (R)-N-(4'-substituted)benzyl 2-acetamido-3-methoxypropionamides. Journal of Medicinal Chemistry. 53: 1288-305. PMID 20041718 DOI: 10.1021/Jm901563P  0.78
2009 Park KD, Morieux P, Salomé C, Cotten SW, Reamtong O, Eyers C, Gaskell SJ, Stables JP, Liu R, Kohn H. Lacosamide isothiocyanate-based agents: novel agents to target and identify lacosamide receptors. Journal of Medicinal Chemistry. 52: 6897-911. PMID 19795888 DOI: 10.1021/Jm9012054  0.762
2009 Lee SH, Kohn H. Nucleophilic activation of a tetra-substituted mitomycin cyclic bis-disulfide. Chemical & Pharmaceutical Bulletin. 57: 149-57. PMID 19182404 DOI: 10.1248/Cpb.57.149  0.404
2009 LEGALL P, SAWHNEY KN, CONLEY JD, KOHN H. Synthesis of functionalized non-natural amino acid derivatives via amidoalkylation transformations International Journal of Peptide and Protein Research. 32: 279-291. DOI: 10.1111/J.1399-3011.1988.Tb01262.X  0.309
2008 Morieux P, Stables JP, Kohn H. Synthesis and anticonvulsant activities of N-benzyl (2R)-2-acetamido-3-oxysubstituted propionamide derivatives. Bioorganic & Medicinal Chemistry. 16: 8968-75. PMID 18789868 DOI: 10.1016/J.Bmc.2008.08.055  0.778
2005 Kohn H, Widger W. The molecular basis for the mode of action of bicyclomycin. Current Drug Targets. Infectious Disorders. 5: 273-95. PMID 16181146 DOI: 10.2174/1568005054880136  0.301
2005 Brogan AP, Widger WR, Bensadek D, Riba-Garcia I, Gaskell SJ, Kohn H. Development of a technique to determine bicyclomycin-rho binding and stoichiometry by isothermal titration calorimetry and mass spectrometry. Journal of the American Chemical Society. 127: 2741-51. PMID 15725032 DOI: 10.1021/Ja046441Q  0.662
2005 Brogan AP, Verghese J, Widger WR, Kohn H. Bismuth-dithiol inhibition of the Escherichia coli rho transcription termination factor. Journal of Inorganic Biochemistry. 99: 841-51. PMID 15708806 DOI: 10.1016/J.Jinorgbio.2004.12.019  0.684
2005 Lee SH, Kohn H. 7-N,7'-N'-(1",2"-Dithianyl-3",6"-dimethylenyl)bismitomycin C: synthesis and nucleophilic activation of a dimeric mitomycin. Organic & Biomolecular Chemistry. 3: 471-82. PMID 15678185 DOI: 10.1039/B414806A  0.39
2005 Skordalakes E, Brogan AP, Park BS, Kohn H, Berger JM. Structural mechanism of inhibition of the Rho transcription termination factor by the antibiotic bicyclomycin. Structure (London, England : 1993). 13: 99-109. PMID 15642265 DOI: 10.1016/J.Str.2004.10.013  0.679
2005 Jin AY, Kohn H, Béguin C, Andurkar SV, Stables JP, Weaver DF. A quantitative structure-activity relationship study for α-substituted acetamido-N-benzylacetamide derivatives - A novel anticonvulsant drug class Canadian Journal of Chemistry. 83: 37-45. DOI: 10.1139/V04-160  0.403
2005 Lee SH, Brodnick RL, Glish GL, Kohn H. 3,8,11,16-Tetrakis(aminomethyl)-1,2,9,10-tetrathia-cyclohexadecane tetra-trifluoroacetic acid: Synthetic precursor to a novel thio-substituted diamine Tetrahedron. 61: 1749-1754. DOI: 10.1016/J.Tet.2004.12.030  0.336
2004 Béguin C, LeTiran A, Stables JP, Voyksner RD, Kohn H. N-Substituted amino acid N'-benzylamides: synthesis, anticonvulsant, and metabolic activities. Bioorganic & Medicinal Chemistry. 12: 3079-96. PMID 15142567 DOI: 10.1016/J.Bmc.2004.02.043  0.375
2004 Kim MG, Bodor ET, Harden TK, Kohn H. C(8)-substituted 1-azabicyclo[3.3.1]non-3-enes: a novel scaffold for muscarinic receptor ligands. Bioorganic & Medicinal Chemistry. 12: 2357-67. PMID 15080933 DOI: 10.1016/J.Bmc.2004.02.016  0.332
2003 Vedejs E, Naidu BN, Klapars A, Warner DL, Li VS, Na Y, Kohn H. Synthetic enantiopure aziridinomitosenes: preparation, reactivity, and DNA alkylation studies. Journal of the American Chemical Society. 125: 15796-806. PMID 14677970 DOI: 10.1021/Ja030452M  0.558
2003 Béguin C, Andurkar SV, Jin AY, Stables JP, Weaver DF, Kohn H. Functionalized amido ketones: new anticonvulsant agents. Bioorganic & Medicinal Chemistry. 11: 4275-85. PMID 12951158 DOI: 10.1016/S0968-0896(03)00434-6  0.345
2003 Brogan AP, Widger WR, Kohn H. Bicyclomycin fluorescent probes: synthesis and biochemical, biophysical, and biological properties. The Journal of Organic Chemistry. 68: 5575-87. PMID 12839449 DOI: 10.1021/Jo030020U  0.677
2003 Kim MG, Bodor ET, Wang C, Harden TK, Kohn H. C(8) substituted 1-azabicyclo[3.3.1]non-3-enes and C(8) substituted 1-azabicyclo[3.3.1]nonan-4-ones: novel muscarinic receptor antagonists. Journal of Medicinal Chemistry. 46: 2216-26. PMID 12747793 DOI: 10.1021/Jm020572P  0.402
2003 Lee SH, Kohn H. Phosphine-assisted rearrangement of 4,5-dihydroxy-1,2-dithianes to 4-hydroxy-3-mercaptotetrahydrothiophenes Heterocycles. 60: 47-56. DOI: 10.3987/Com-02-9603  0.306
2002 LeTiran A, Stables JP, Kohn H. Design and evaluation of affinity labels of functionalized amino acid anticonvulsants. Journal of Medicinal Chemistry. 45: 4762-73. PMID 12361404 DOI: 10.1021/Jm020225F  0.401
2002 Shen M, LeTiran A, Xiao Y, Golbraikh A, Kohn H, Tropsha A. Quantitative structure-activity relationship analysis of functionalized amino acid anticonvulsant agents using k nearest neighbor and simulated annealing PLS methods. Journal of Medicinal Chemistry. 45: 2811-23. PMID 12061883 DOI: 10.1021/Jm010488U  0.303
2002 Na Y, Wang S, Kohn H. 7-N-(mercaptoalkyl)mitomycins: implications of cyclization for drug function. Journal of the American Chemical Society. 124: 4666-77. PMID 11971715 DOI: 10.1021/Ja0124313  0.625
2001 Na Y, Li VS, Nakanishi Y, Bastow KF, Kohn H. Synthesis, DNA cross-linking activity, and cytotoxicity of dimeric mitomycins. Journal of Medicinal Chemistry. 44: 3453-62. PMID 11585450 DOI: 10.1021/Jm010090Y  0.516
2001 Vincent F, Srinivasan J, Santillán A, Widger WR, Kohn H. C(5)-C(5a)-modified bicyclomycins: synthesis, structure, and biochemical and biological properties. The Journal of Organic Chemistry. 66: 2251-64. PMID 11281764 DOI: 10.1021/Jo0013150  0.355
2001 Na Y, Kohn H. Quinone-cyclized porfiromycins Heterocycles. 55: 1347-1363. DOI: 10.3987/Com-01-9215  0.568
2000 Vincent F, Openshaw M, Trautwein M, Gaskell SJ, Kohn H, Widger WR. Rho transcription factor: symmetry and binding of bicyclomycin. Biochemistry. 39: 9077-83. PMID 10924100 DOI: 10.1021/Bi000504+  0.318
2000 Vincent F, Widger WR, Openshaw M, Gaskell SJ, Kohn H. 5a-formylbicyclomycin: studies on the bicyclomycin-Rho interaction. Biochemistry. 39: 9067-76. PMID 10924099 DOI: 10.1021/Bi000503H  0.367
2000 Wang C, Kohn H. Formation of aromatic rings through enamine annulation Organic Letters. 2: 1773-5. PMID 10880223 DOI: 10.1021/Ol000093P  0.348
2000 Li VS, Reed M, Zheng Y, Kohn H, Tang M. C5 cytosine methylation at CpG sites enhances sequence selectivity of mitomycin C-DNA bonding. Biochemistry. 39: 2612-8. PMID 10704210 DOI: 10.1021/Bi991307H  0.303
1999 Andurkar SV, Stables JP, Kohn H. The anticonvulsant activities of N-benzyl 3-methoxypropionamides. Bioorganic & Medicinal Chemistry. 7: 2381-9. PMID 10632047 DOI: 10.1016/S0968-0896(99)00186-8  0.394
1999 Wang S, Kohn H. Studies on the mode of action of mitomycin C(7) aminoethylene disulfides (BMS-181174 and KW-2149): reactivity of 7-N-(mercaptoethyl)mitomycin C. Journal of Medicinal Chemistry. 42: 788-90. PMID 10072677 DOI: 10.1021/Jm9806796  0.324
1998 Riba I, Gaskell SJ, Cho H, Widger WR, Kohn H. Evidence for the location of bicyclomycin binding to the Escherichia coli transcription termination factor Rho. The Journal of Biological Chemistry. 273: 34033-41. PMID 9852059 DOI: 10.1074/Jbc.273.51.34033  0.349
1997 Huh N, Kogan TP, Kohn H. Synthesis of N-substituted 10-des(carbamoyloxy)-10-azidomitomycins Synthesis. 921-924. DOI: 10.1055/S-1997-1297  0.332
1997 Cho H, Park HG, Zhang X, Riba I, Gaskell SJ, Widger WR, Kohn H. Design, syntheses, and evaluations of bicyclomycin-based rho inactivators Journal of Organic Chemistry. 62: 5432-5440. DOI: 10.1021/Jo970575N  0.375
1996 Santillán A, Park Hg, Zhang X, Lee OS, Widger WR, Kohn H. Role of the [4.2.2] Bicyclic Unit in Bicyclomycin: Synthesis, Structure, Chemical, Biochemical, and Biological Properties. The Journal of Organic Chemistry. 61: 7756-7763. PMID 11667731 DOI: 10.1021/Jo961003Q  0.423
1996 Park Hg, Zhang X, Widger WR, Kohn H. Role of the C(1) Triol Group in Bicyclomycin: Synthesis and Biochemical and Biological Properties. The Journal of Organic Chemistry. 61: 7750-7755. PMID 11667730 DOI: 10.1021/Jo961002Y  0.37
1996 Choi D, Stables JP, Kohn H. The anticonvulsant activities of functionalized N-benzyl 2-acetamidoacetamides. The importance of the 2-acetamido substituent Bioorganic and Medicinal Chemistry. 4: 2105-2114. PMID 9022975 DOI: 10.1016/S0968-0896(96)00225-8  0.389
1996 Huh N, Rege AA, Yoo B, Kogan TP, Kohn H. Design, synthesis, and evaluation of mitomycin-tethered phosphorothioate oligodeoxynucleotides Bioconjugate Chemistry. 7: 659-669. PMID 8950485 DOI: 10.1021/Bc960060N  0.388
1996 Magyar A, Zhang X, Kohn H, Widger WR. The antibiotic bicyclomycin affects the secondary RNA binding site of Escherichia coli transcription termination factor Rho Journal of Biological Chemistry. 271: 25369-25374. PMID 8810302 DOI: 10.1074/Jbc.271.41.25369  0.326
1996 Choi D, Stables JP, Kohn H. Synthesis and anticonvulsant activities of N-benzyl-2-acetamidopropionamide derivatives Journal of Medicinal Chemistry. 39: 1907-1916. PMID 8627614 DOI: 10.1021/Jm9508705  0.394
1996 Wang S, Kohn H. Mitomycin betaines: Synthesis, structure, and solvolytic reactivity Journal of Organic Chemistry. 61: 9202-9206. DOI: 10.1021/Jo961378B  0.34
1996 Kohn H, Wang S. Studies on the mechanism of activation of C(7) ethylenediamine substituted mitomycins. Relevance to the proposed mode of action of BMY-25067 and KW-2149 Tetrahedron Letters. 37: 2337-2340. DOI: 10.1016/0040-4039(96)00279-1  0.358
1995 Park Hg, Zhang X, Moon Hs, Zwiefka A, Cox K, Gaskell SJ, Widger WR, Kohn H. Bicyclomycin and Dihydrobicyclomycin Inhibition Kinetics ofEscherichia colirho-Dependent Transcription Termination Factor ATPase Activity Archives of Biochemistry and Biophysics. 323: 447-454. PMID 7487110 DOI: 10.1006/Abbi.1995.0066  0.333
1994 Kohn H, Sawhney KN, Robertson DW, Leander JD. Anticonvulsant properties of N-substituted alpha,alpha-diamino acid derivatives. Journal of Pharmaceutical Sciences. 83: 689-91. PMID 8071822 DOI: 10.1002/Jps.2600830519  0.323
1994 Bardel P, Bolanos A, Kohn H. Synthesis and anticonvulsant activities of alpha-acetamido-N-benzylacetamide derivatives containing an electron-deficient alpha-heteroaromatic substituent. Journal of Medicinal Chemistry. 37: 4567-4571. PMID 7799408 DOI: 10.1021/Jm00052A017  0.336
1994 Zhang Z, Kohn H. The role of the C-1 triol group in bicyclomycin Journal of the Chemical Society, Chemical Communications. 1343-1344. DOI: 10.1039/C39940001343  0.368
1994 Zhang Z, Kohn H. Chemical, biochemical, and biological studies on select C(1) triol modified bicyclomycins Journal of the American Chemical Society. 116: 9815-9826. DOI: 10.1021/Ja00101A001  0.312
1994 Park HG, Vela MA, Kohn H. Synthesis and reactivity of bicyclomycin C(3′) amines Journal of the American Chemical Society. 116: 471-478. DOI: 10.1021/Ja00081A006  0.396
1992 Han I, Russell DJ, Kohn H. Studies on the mechanism of mitomycin C(1) electrophilic transformations: structure-reactivity relationships The Journal of Organic Chemistry. 57: 1799-1807. DOI: 10.1021/Jo00032A037  0.32
1992 Schiltz P, Kohn H. Sodium dithionite-mediated mitomycin C reductive activation processes Tetrahedron Letters. 33: 4709-4712. DOI: 10.1016/S0040-4039(00)61265-0  0.329
1991 Hong YP, Kohn H. Studies on the use of chromium dichlorate for the reductive activation of Mitomycin C Journal of the American Chemical Society. 113: 4634-4644. DOI: 10.1021/Ja00012A036  0.334
1990 Lee C‐, Kohn H. Anticonvulsant Properties of 3-Oxo- and 3-Imino-4-Substituted 1,2,5-Thiadiazolidine 1,1-Dioxides Journal of Pharmaceutical Sciences. 79: 716-718. PMID 2231335 DOI: 10.1002/Jps.2600790813  0.343
1990 Kohn H, J. Russell D. Development of a Hydrazine-mediated System for the Reductive Activation of Mitomycin C Heterocycles. 31: 223. DOI: 10.3987/Com-89-5270  0.348
1990 Lee CH, Kohn H. Intra- and intermolecular .alpha.-sulfamidoalkylation reactions The Journal of Organic Chemistry. 55: 6098-6104. DOI: 10.1021/Jo00312A013  0.354
1989 Sawhney KN, Kohn H. Mitomycin C analogues with a substituted hydrazine at position 7. Synthesis, spectral properties, and biological activity. Journal of Medicinal Chemistry. 32: 248-252. PMID 2909738 DOI: 10.1021/Jm00121A044  0.375
1988 Kohn H, Conley JD, Leander JD. Marked stereospecificity in a new class of anticonvulsants. Brain Research. 457: 371-5. PMID 3219563 DOI: 10.1016/0006-8993(88)90709-3  0.311
1988 Kohn H, Abuzar S, Korp JD, Zektzer AS, Martin GE. Structural studies of bicyclomycin Journal of Heterocyclic Chemistry. 25: 1511-1517. DOI: 10.1002/Jhet.5570250548  0.326
1987 Conley JD, Kohn H. Functionalized DL-amino acid derivatives. Potent new agents for the treatment of epilepsy. Journal of Medicinal Chemistry. 30: 567-574. PMID 3820228 DOI: 10.1021/Jm00386A021  0.362
1987 Kohn H, Zein N, Lin XQ, Ding JQ, Kadish KM. Mechanistic studies on the mode of reaction of mitomycin C under catalytic and electrochemical reductive conditions Journal of the American Chemical Society. 109: 1833-1840. DOI: 10.1021/Ja00240A038  0.327
1985 Cortes S, Liao ZK, Watson D, Kohn H. Effect of structural modification of the hydantoin ring on anticonvulsant activity. Journal of Medicinal Chemistry. 28: 601-606. PMID 3989820 DOI: 10.1021/Jm50001A012  0.364
1985 Liao ZK, Kohn H. Synthesis of spiroimidazolidin-2-ones via intramolecular N-carbamoyliminium ion cyclization reactions Journal of Organic Chemistry. 50: 1884-1888. DOI: 10.1021/Jo00211A020  0.326
1985 Cortes S, Liao Z, Watson D, Kohn H. Additions and Corrections - Effect of Structural Modification of the Hydantoin Ring on Anticonvulsant Activity Journal of Medicinal Chemistry. 28: 1965-1965. DOI: 10.1021/Jm00150A604  0.311
1985 Cortes S, Liao Z-, Watson D, Kohn H. Effect Of Structural Modification Of The Hydantoin Ring On Anticonvulsant Activity Cheminform. 16. DOI: 10.1002/Chin.198534214  0.311
1985 Bean M, Kohn H. Studies on the reaction of mitomycin C with potassium thiobenzoate under reductive conditions The Journal of Organic Chemistry. 50: 293-298. DOI: 10.1002/Chin.198525374  0.744
1983 Bean M, Kohn H. Studies on the reaction of mitomycin C with potassium ethyl monothiocarbonate under reductive conditions The Journal of Organic Chemistry. 48: 5033-5041. DOI: 10.1002/Chin.198427181  0.746
1983 Hornemann U, Iguchi K, Keller PJ, Vu HM, Kozlowski JF, Kohn H. Reactions of mitomycin C with potassium ethyl xanthate in neutral aqueous solution The Journal of Organic Chemistry. 48: 5026-5033. DOI: 10.1002/Chin.198427180  0.316
1981 Kohn H, Bean MB, von Rohrscheidt C, Willcott MR, Warnhoff EW. Participation in the formation of iodo ureas from 3-buten-1-ol derivatives. A reinvestigation1 1 Alfred P. Sloan Fellow, 1977-1981. Camille and Henry Dreyfus Teacher-Scholar Grant Recipient, 1977-1982. Tetrahedron. 37: 3195-3201. DOI: 10.1016/S0040-4020(01)98853-2  0.715
1981 Flaster H, Kohn H. Syntheses and spectral properties of 2-Thiobiotin and biotin derivatives Journal of Heterocyclic Chemistry. 18: 1425-1436. DOI: 10.1002/Jhet.5570180730  0.307
1978 Arceneaux JH, Kohn H, Steenberg ML, Buckley JP. Syntheses and pharmacological activity of N-acyl-substituted imidazolidinethiones and thioimidazolines. Journal of Pharmaceutical Sciences. 67: 600-2. PMID 641789 DOI: 10.1002/Jps.2600670506  0.367
1978 Kohn H, Charumilind P, Gopichand Y. Studies of the reaction of thiocarbonyl-containing compounds with ketenes The Journal of Organic Chemistry. 43: 4961-4965. DOI: 10.1002/Chin.197918249  0.315
1977 Kohn H, Kohn BA, Steenberg ML, Buckley JP. Syntheses and pharmacological activity of substituted imidazolidinethiones and thioimidazolines Journal of Medicinal Chemistry. 20: 158-160. PMID 833815 DOI: 10.1021/Jm00211A034  0.3
1977 Kohn H, Arceneaux JH. Thermolysis of N-acyl substituted 2-allylthioimidazolines. Evidence for a [3,3] sigmatropic rearrangement The Journal of Organic Chemistry. 42: 2339-2341. DOI: 10.1002/Chin.197742178  0.326
1977 Arceneaux JH, Kohn H, Steenberg ML, Buckley JP. Syntheses And Pharmacological Activity Of N-Acyl-Substituted Imidazolidinethiones And Thioimidazolines Cheminform. 8. DOI: 10.1002/Chin.197721214  0.371
1977 Kohn H, Davis RE. Syntheses and chemistry of N-acyl substituted dihydroimidazo[2,1-b]thiazolium salts Journal of Organic Chemistry. 42: 72-77. DOI: 10.1002/Chin.197720253  0.313
1976 Breslow R, Kohn H, Siegel B. Methylated cyclodextrin and a cyclodextrin polymer as catalysts in selective anisole chlorination Tetrahedron Letters. 17: 1645-1646. DOI: 10.1016/S0040-4039(00)92912-5  0.432
1972 Kohn H, Benkovic SJ, Olofson RA. Dependence of mechanism on pH for deuterium-hydrogen exchange in 1-methyltetrazole-5-d. Transition metal ion catalysis of a deprotonation process. Journal of the American Chemical Society. 94: 5759-65. PMID 5053862 DOI: 10.1021/Ja00771A037  0.501
1972 Kohn H, Olofson RA. 1,4-Dimethyl-1,4-dihydro-1,2,4,5-tetrazine and its N-alkyl salt. Synthesis, structure, and chemistry The Journal of Organic Chemistry. 37: 3504-3509. DOI: 10.1021/jo00795a024  0.589
Low-probability matches (unlikely to be authored by this person)
2004 Lee SH, Kohn H. Cyclic disulfide C8 iminoporfiromycin: nucleophilic activation of a porfiromycin. Journal of the American Chemical Society. 126: 4281-92. PMID 15053618 DOI: 10.1021/ja030577r  0.3
1985 Jung SH, Kohn H. Stereoselective synthesis of vicinal diamines from alkenes and cyanamide Journal of the American Chemical Society. 107: 2931-2943. DOI: 10.1002/Chin.198542125  0.299
2002 Xu Y, Kohn H, Widger WR. Mutations in the rho transcription termination factor that affect RNA tracking. The Journal of Biological Chemistry. 277: 30023-30. PMID 12034708 DOI: 10.1074/Jbc.M111009200  0.297
2013 Lee H, Park KD, Yang XF, Dustrude ET, Wilson SM, Khanna R, Kohn H. (Biphenyl-4-yl)methylammonium chlorides: potent anticonvulsants that modulate Na+ currents. Journal of Medicinal Chemistry. 56: 5931-9. PMID 23772678 DOI: 10.1021/Jm4007092  0.296
1985 Liao Z‐, Kohn H. Synthesis Of Spiroimidazolidin-2-Ones Via Intramolecular N-Carbamoyliminium Ion Cyclization Reactions Cheminform. 16. DOI: 10.1002/Chin.198543229  0.293
1992 Vela MA, Kohn H. Observations concerning the reactivity of bicyclomycin and bicyclomycin derivatives with organophosphorus reagents The Journal of Organic Chemistry. 57: 6650-6653. DOI: 10.1021/Jo00050A055  0.293
1995 Choi D, Kohn H. Trimethylsilyl halides: Effective reagents for the synthesis of β-halo amino acid derivatives Tetrahedron Letters. 36: 7011-7014. DOI: 10.1016/0040-4039(95)01451-M  0.293
2015 Torregrosa R, Yang XF, Dustrude ET, Cummins TR, Khanna R, Kohn H. Chimeric derivatives of functionalized amino acids and α-aminoamides: Compounds with anticonvulsant activity in seizure models and inhibitory actions on central, peripheral, and cardiac isoforms of voltage-gated sodium channels. Bioorganic & Medicinal Chemistry. 23: 3655-66. PMID 25922183 DOI: 10.1016/J.Bmc.2015.04.014  0.292
1990 Lee C, Kohn H. Functionalized 5,6-dihydro-2H-1,2,6-thiadiazine 1,1-dioxides. Synthesis, structure and chemistry Journal of Heterocyclic Chemistry. 27: 2107-2111. DOI: 10.1002/Jhet.5570270747  0.288
1993 Zwiefka A, Kohn H, Widger WR. Transcription termination factor rho: the site of bicyclomycin inhibition in Escherichia coli. Biochemistry. 32: 3564-70. PMID 8466900 DOI: 10.1021/Bi00065A007  0.287
2001 LeTiran A, Stables JP, Kohn H. Functionalized amino acid anticonvulsants: synthesis and pharmacological evaluation of conformationally restricted analogues. Bioorganic & Medicinal Chemistry. 9: 2693-708. PMID 11557357 DOI: 10.1016/S0968-0896(01)00204-8  0.286
1978 Kohn H, Gopichand Y, Charumilind P. Studies on the reaction of acylimidazolidones with ketenes The Journal of Organic Chemistry. 43: 4955-4961. DOI: 10.1002/Chin.197918245  0.285
2002 Weber TP, Widger WR, Kohn H. The Mg2+ requirements for rho transcription termination factor: catalysis and bicyclomycin inhibition. Biochemistry. 41: 12377-83. PMID 12369827 DOI: 10.1021/Bi020420W  0.285
1988 Kohn H, Lee C. 3,7-Bis(carbothoxy)perhydro-1,5,2,4,6,8-dithiatetrazocime 1,1,5,5-tetroxide. Synthesis, Structure and Chemistry Heterocycles. 27: 2581. DOI: 10.3987/Com-88-4618  0.284
1980 Charumilind P, Kohn H. Studies on the reaction of 3,3,4,4-tetraphenylthietan-2-one The Journal of Organic Chemistry. 45: 4359-4365. DOI: 10.1021/Jo01310A019  0.283
2003 Weber TP, Widger WR, Kohn H. Metal-1,4-dithio-2,3-dihydroxybutane chelates: novel inhibitors of the Rho transcription termination factor. Biochemistry. 42: 9121-6. PMID 12885245 DOI: 10.1021/Bi030089W  0.283
2003 Xu Y, Johnson J, Kohn H, Widger WR. ATP binding to Rho transcription termination factor. Mutant F355W ATP-induced fluorescence quenching reveals dynamic ATP binding. The Journal of Biological Chemistry. 278: 13719-27. PMID 12551938 DOI: 10.1074/Jbc.M212979200  0.282
2004 Shen M, Béguin C, Golbraikh A, Stables JP, Kohn H, Tropsha A. Application of predictive QSAR models to database mining: identification and experimental validation of novel anticonvulsant compounds. Journal of Medicinal Chemistry. 47: 2356-64. PMID 15084134 DOI: 10.1021/Jm030584Q  0.281
1984 Liao ZK, Kohn H. Intramolecular N-carbamoyliminium ion cyclizations of unactivated alkenes and acetylenes The Journal of Organic Chemistry. 49: 3812-3819. DOI: 10.1002/Chin.198510254  0.279
2007 Stöhr T, Kupferberg HJ, Stables JP, Choi D, Harris RH, Kohn H, Walton N, White HS. Lacosamide, a novel anti-convulsant drug, shows efficacy with a wide safety margin in rodent models for epilepsy. Epilepsy Research. 74: 147-54. PMID 17433624 DOI: 10.1016/J.Eplepsyres.2007.03.004  0.276
1979 von Rohrscheidt C, Kohn H. Selective formation and hydrolysis of derivatives of 4-iodo-3-ureido-1-butanol Tetrahedron Letters. 20: 215-218. DOI: 10.1016/S0040-4039(01)85926-8  0.274
2006 Zhang S, Golbraikh A, Oloff S, Kohn H, Tropsha A. A novel automated lazy learning QSAR (ALL-QSAR) approach: method development, applications, and virtual screening of chemical databases using validated ALL-QSAR models. Journal of Chemical Information and Modeling. 46: 1984-95. PMID 16995729 DOI: 10.1021/Ci060132X  0.269
1977 Kohn H, Cravey MJ, Arceneaux JH, Cravey RL, Willcott MR. Syntheses and spectral properties of substituted imidazolidones and imidazolines The Journal of Organic Chemistry. 42: 941-948. DOI: 10.1002/Chin.197729218  0.267
2005 Duncan GE, Kohn H. The novel antiepileptic drug lacosamide blocks behavioral and brain metabolic manifestations of seizure activity in the 6 Hz psychomotor seizure model. Epilepsy Research. 67: 81-7. PMID 16214306 DOI: 10.1016/J.Eplepsyres.2005.08.009  0.267
1991 Li VS, Kohn H. Studies on the bonding specificity for mitomycin C-DNA monoalkylation processes Journal of the American Chemical Society. 113: 275-283. DOI: 10.1021/Ja00001A040  0.261
1984 Liao ZK, Kohn H. Synthesis of substituted 2-imidazolidinones and annelated hydantoins via amidoalkylation transformations The Journal of Organic Chemistry. 49: 4745-4752. DOI: 10.1002/Chin.198519204  0.26
1998 Santillán A, Zhang X, Widger WR, Kohn H. 5a-methyl-substituted bicyclomycins: Synthesis and chemical, biochemical, and biological properties Journal of Organic Chemistry. 63: 1290-1298. DOI: 10.1021/Jo972055Y  0.259
2001 Zewail-Foote M, Li VS, Kohn H, Bearss D, Guzman M, Hurley LH. The inefficiency of incisions of ecteinascidin 743-DNA adducts by the UvrABC nuclease and the unique structural feature of the DNA adducts can be used to explain the repair-dependent toxicities of this antitumor agent. Chemistry & Biology. 8: 1033-49. PMID 11731295 DOI: 10.1016/S1074-5521(01)00071-0  0.258
1998 Santillán A, Zhang X, Hardesty J, Widger WR, Kohn H. Role of the C(6)-hydroxy group in bicyclomycin: synthesis, structure, and chemical, biochemical, and biological properties. Journal of Medicinal Chemistry. 41: 1185-94. PMID 9544218 DOI: 10.1021/Jm9708386  0.257
1979 Kohn H, Charumilind P, Simonsen SH. 3,3,4,4-Tetraphenyl-1,2-Oxathiolan-5-One 2-Oxide. Synthesis, Structure, And Selected Chemistry Cheminform. 10. DOI: 10.1002/Chin.197951221  0.255
2015 Park KD, Yang XF, Dustrude ET, Wang Y, Ripsch MS, White FA, Khanna R, Kohn H. Chimeric agents derived from the functionalized amino acid, lacosamide, and the α-aminoamide, safinamide: evaluation of their inhibitory actions on voltage-gated sodium channels, and antiseizure and antinociception activities and comparison with lacosamide and safinamide. Acs Chemical Neuroscience. 6: 316-30. PMID 25418676 DOI: 10.1021/Cn5002182  0.255
2002 Lee SH, Kohn H. Efficient synthesis of medium-sized cyclic ether diamines. The Journal of Organic Chemistry. 67: 1692-5. PMID 11871906 DOI: 10.1021/Jo0108663  0.253
2006 Park BS, Widger W, Kohn H. Fluorine-substituted dihydrobicyclomycins: synthesis and biochemical and biological properties. Bioorganic & Medicinal Chemistry. 14: 41-61. PMID 16185879 DOI: 10.1016/J.Bmc.2005.07.075  0.248
1983 Kohn H, Jung SH. New stereoselective method for the preparation of vicinal diamines from olefins and cyanamide Journal of the American Chemical Society. 105: 4106-4108. DOI: 10.1002/Chin.198339164  0.247
1989 Lee CH, Korp JD, Kohn H. 3-Oxo- and 3-imino-4-substituted-1,2,5-thiadiazolidine 1,1-dioxides: synthesis, spectral properties, and selected chemistry The Journal of Organic Chemistry. 54: 3077-3083. DOI: 10.1021/Jo00274A023  0.242
1995 Choi D, Yoo B, Colson KL, Martin GE, Kohn H. C(10) halogen 10-des(carbamoyloxy)porfiromycins: Synthesis, chemistry, and biological activity Journal of Organic Chemistry. 60: 3391-3396.  0.241
1992 Vela MA, Kohn H. The synthesis and reactivity of [N(8)-C(3')]-cyclized bicyclomycin. Evidence of the role of the C(1)-triol group in bicyclomycin-mediated processes The Journal of Organic Chemistry. 57: 5223-5231. DOI: 10.1021/jo00045a041  0.238
1997 Wang S, Kohn H. C(7)-Substituted Diaminomitomycins: Synthesis, Structure, and Chemical Reactivity Journal of Organic Chemistry. 62: 5404-5412.  0.238
1986 Zein N, Kohn H. The electrophilic and nucleophilic character of the carbon-10 methylene group in mitosenes revealed Journal of the American Chemical Society. 108: 296-297. DOI: 10.1021/Ja00262A019  0.23
1986 Zein N, Kohn H. Electrophilic and Nucleophilic Character of the Carbon 10 Methylene Group in Mitosenes Revealed. Cheminform. 17. DOI: 10.1002/Chin.198620117  0.23
1976 Kohn H. Model studies on the mechanism of biotin dependent carboxylations. Journal of the American Chemical Society. 98: 3690-9. PMID 5480 DOI: 10.1021/Ja00428A050  0.228
1996 Park Hg, Zhang Z, Zhang X, Widger WR, Kohn H. Role of the C(5)-C(5a) Exomethylene Group in Bicyclomycin: Synthesis, Structure, and Biochemical and Biological Properties. The Journal of Organic Chemistry. 61: 7764-7776. PMID 11667732 DOI: 10.1021/Jo961004I  0.228
2009 Park KD, Liu R, Kohn H. Useful tools for biomolecule isolation, detection, and identification: acylhydrazone-based cleavable linkers. Chemistry & Biology. 16: 763-72. PMID 19635413 DOI: 10.1016/J.Chembiol.2009.06.005  0.226
1980 Cravey MJ, Kohn H. Model studies on the mechanism of biotin-dependent carboxylations. 2. Site of protonation vs. carbon dioxide transfer Journal of the American Chemical Society. 102: 3928-3939. DOI: 10.1021/Ja00531A041  0.224
2003 Weber TP, Widger WR, Kohn H. Metal dependency for transcription factor rho activation. Biochemistry. 42: 1652-9. PMID 12578379 DOI: 10.1021/Bi020601Y  0.224
2010 HONG YP, KOHN H. ChemInform Abstract: Cr(ClO4)2: An Effective Reagent for the Preparation of Mitomycin C Nucleophilic Substituted Compounds. Cheminform. 23: no-no. DOI: 10.1002/chin.199217151  0.222
1981 Cravey M, Kohn H. Correction - Model Studies on the Mechanism of Botin-Dependent Carboxylations. 2. Site of Protonation vs. CO2 Transfer Journal of the American Chemical Society. 103: 2143-2143. DOI: 10.1021/Ja00398A602  0.222
1972 KOHN H, BENKOVIC SJ, OLOFSON RA. ChemInform Abstract: PH-ABHAENGIGKEIT DES MECHANISMUS FUER DEN D-H-AUSTAUSCH VON (5D)-1-METHYL-TETRAZOL, UEBERGANGSMETALLKATALYSIERTER DEPROTONIERUNGSPROZESS Chemischer Informationsdienst. 3. DOI: 10.1002/Chin.197244143  0.219
2001 Andurkar SV, Béguin C, Stables JP, Kohn H. Synthesis and structural studies of aza analogues of functionalized amino acids: new anticonvulsant agents. Journal of Medicinal Chemistry. 44: 1475-8. PMID 11311072 DOI: 10.1021/jm000517l  0.218
1991 Hong YP, Kohn H. Chromium(II) perchlorate: an effective reagent for the preparation of mitomycin C nucleophilic substituted compounds The Journal of Organic Chemistry. 56: 6479-6482. DOI: 10.1021/jo00022a049  0.216
1998 Andurkar SV, Stables JP, Kohn H. Synthesis and anticonvulsant activities of (R)-(O)-methylserine derivatives Tetrahedron Asymmetry. 9: 3841-3854.  0.214
1996 Li VS, Choi D, Wang Z, Jimenez LS, Tang MS, Kohn H. Role of the C-10 substituent in mitomycin C-1-DNA bonding Journal of the American Chemical Society. 118: 2326-2331. DOI: 10.1021/Ja953871V  0.213
1992 Schiltz P, Kohn H. Reductively activated mitomycin C: an efficient trapping reagent for electrophiles Journal of the American Chemical Society. 114: 7958-7959. DOI: 10.1021/ja00046a079  0.212
1983 Chiu IC, Kohn H. Syntheses and reactivity of trans-6-azabicyclo[3.1.0]hexan-2-ol derivatives and indanol[1,2-b]aziridine. Structural analogs of mitomycin C The Journal of Organic Chemistry. 48: 2857-2866. DOI: 10.1021/jo00165a015  0.208
1993 Schiltz P, Kohn H. Studies on the use of disodium dithionite for the reductive activation of mitomycin C Journal of the American Chemical Society. 115: 10497-10509. DOI: 10.1021/ja00076a006  0.205
2003 Kim MG, Strych U, Krause K, Benedik M, Kohn H. N(2)-substituted D,L-cycloserine derivatives: synthesis and evaluation as alanine racemase inhibitors. The Journal of Antibiotics. 56: 160-8. PMID 12715876 DOI: 10.7164/Antibiotics.56.160  0.204
1976 Kohn H, Gopichand Y. An isosteric substitution reaction of substituted imidazolidinethiones Tetrahedron Letters. 17: 3093-3096. DOI: 10.1016/S0040-4039(00)93850-4  0.2
1978 Watkins SF, Kohn H, Bernal I. Crystal and molecular structure of methyl 3-methyl-2-thioxoimidazol- idine-1 -carboxylate. A possible structural analogue for carboxybiotin Journal of the Chemical Society, Perkin Transactions 2. 26-29. DOI: 10.1039/P29780000026  0.2
1992 Kohn H, Li VS, Schiltz P, Tang MS. On the origins of the DNA sequence selectivity of mitomycin monoalkylation transformations Journal of the American Chemical Society. 114: 9218-9220. DOI: 10.1021/Ja00049A082  0.199
2017 Bosetti F, Koenig JI, Ayata C, Back SA, Becker K, Broderick JP, Carmichael ST, Cho S, Cipolla MJ, Corbett D, Corriveau RA, Cramer SC, Ferguson AR, Finklestein SP, Ford BD, ... ... Kohn H, et al. Translational Stroke Research: Vision and Opportunities. Stroke. PMID 28751554 DOI: 10.1161/Strokeaha.117.017112  0.198
1990 Kohn H, Hong YP. Observations on the activation of mitomycin C. Requirements for C-10 functionalization Journal of the American Chemical Society. 112: 4596-4598. DOI: 10.1021/ja00167a097  0.197
1995 Li VS, Choi D, Tang MS, Kohn H. Structural requirements for mitomycin C DNA bonding Biochemistry. 34: 7120-7126. PMID 7766622  0.195
2009 Park KD, Liu R, Kohn H. Useful Tools for Biomolecule Isolation, Detection, and Identification: Acylhydrazone-Based Cleavable Linkers (DOI:10.1016/j.chembiol.2009.06.005) Chemistry and Biology. 16: 907. DOI: 10.1016/J.Chembiol.2009.08.007  0.193
1987 Zein N, Kohn H. Covalent binding of mitomycin C to nucleosides under reductive conditions Journal of the American Chemical Society. 109: 1576-1577. DOI: 10.1021/ja00239a051  0.192
1973 KOHN H, OLOFSON RA. ChemInform Abstract: 1,4-DIMETHYL-1,4-DIHYDRO-1,2,4,5-TETRAZIN UND SEINE N-ALKYL-SALZE, SYNTH., STRUKTUR UND CHEMIE Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/chin.197309330  0.188
1999 Magyar A, Zhang X, Abdi F, Kohn H, Widger WR. Identifying the bicyclomycin binding domain through biochemical analysis of antibiotic-resistant rho proteins. The Journal of Biological Chemistry. 274: 7316-24. PMID 10066795 DOI: 10.1074/Jbc.274.11.7316  0.186
1977 Kohn H, Davis RE. Syntheses and chemistry of N-acyl substituted dihydroimidazo[2,1-b]thiazolium salts The Journal of Organic Chemistry. 42: 72-77. DOI: 10.1021/jo00421a014  0.179
2005 LeMagueres P, Im H, Ebalunode J, Strych U, Benedik MJ, Briggs JM, Kohn H, Krause KL. The 1.9 A crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active site. Biochemistry. 44: 1471-81. PMID 15683232 DOI: 10.1021/Bi0486583  0.175
2010 HONG YP, KOHN H. ChemInform Abstract: Studies on the Use of Cr(ClO4)2 for the Reductive Activation of Mitomycin C (I). Cheminform. 22: no-no. DOI: 10.1002/chin.199136121  0.174
2009 Salomé C, Kohn H. Triphenylphosphine Dibromide: A Simple One-pot Esterification Reagent. Tetrahedron. 65: 456-460. PMID 20066025 DOI: 10.1016/j.tet.2008.10.062  0.171
2001 Li VS, Tang MS, Kohn H. The effect of C(5) cytosine methylation at CpG sequences on mitomycin-DNA bonding profiles. Bioorganic & Medicinal Chemistry. 9: 863-73. PMID 11354669 DOI: 10.1016/S0968-0896(00)00301-1  0.17
2004 ZEWAILFOOTE M, LI V, KOHN H, BEARSS D, GUZMAN M, HURLEY L. Erratum Chemistry & Biology. 11: 283. DOI: 10.1016/S1074-5521(04)00041-9  0.16
2003 Kim MG, Strych U, Krause K, Benedik M, Kohn H. Evaluation of amino-substituted heterocyclic derivatives as alanine racemase inhibitors Medicinal Chemistry Research. 12: 130-138.  0.155
1989 LEE C, KOHN H. ChemInform Abstract: 3,7-Bis(ethoxycarbonyl)perhydro-1,5,2,4,6,8-dithiatetrazocine 1,1,5,5-Tetroxide. Synthesis, Structure, and Chemistry. Cheminform. 20. DOI: 10.1002/chin.198918246  0.151
1988 Kohn H, Abuzar S. Reinterpretation of the bicyclomycin-sodium methanethiolate reaction Journal of the American Chemical Society. 110: 3661-3663. DOI: 10.1021/ja00219a053  0.149
1982 Kohn H, Liao ZK. N-Amidoyliminium ion cyclizations. Synthesis of annulated imidazolidinones The Journal of Organic Chemistry. 47: 2787-2789. DOI: 10.1021/jo00135a022  0.146
1991 Han I, Kohn H. 7-Aminoaziridinomitosenes: synthesis, structure, and chemistry The Journal of Organic Chemistry. 56: 4648-4653. DOI: 10.1021/jo00015a016  0.134
1988 Abuzar S, Kohn H. Observations on the activation of bicyclomycin Journal of the American Chemical Society. 110: 4089-4090. DOI: 10.1021/ja00220a087  0.131
1997 Magyar A, Zhang X, Kohn H, Widger WR. Biochemical analysis of bicyclomycin resistant e. coli mutant r ho proteins Faseb Journal. 11: A1147.  0.128
1992 Kohn H, Li VS, Tang MS. Recognition of mitomycin C-DNA monoadducts by UVRABC nuclease Journal of the American Chemical Society. 114: 5501-5509. DOI: 10.1021/ja00040a003  0.117
1989 Abuzar S, Kohn H. Studies on the reactivity of bicyclomycin with nucleophilic amino acid derivatives The Journal of Organic Chemistry. 54: 4000-4003. DOI: 10.1021/jo00277a052  0.116
1979 Kohn H, Charumilind P, Simonsen SH. 3,3,4,4-Tetraphenyl-1,2-oxathiolan-5-one 2-oxide. Synthesis, structure, and selected chemistry Journal of the American Chemical Society. 101: 5431-5432. DOI: 10.1021/Ja00512A062  0.109
1996 Santillán A, Kohn H. Novel ring transformations for 5,5a-dibromobicyclomycin and derivatives Tetrahedron. 52: 833-842. DOI: 10.1016/0040-4020(95)00942-6  0.107
1988 Kohn H, Abuzar S. Studies on the chemical reactivity of bicyclomycin: acid hydrolysis The Journal of Organic Chemistry. 53: 2769-2773. DOI: 10.1021/jo00247a020  0.102
1990 Abuzar S, Kohn H. Studies on the reactivity of bicyclomycin with thiols Journal of the American Chemical Society. 112: 3114-3121. DOI: 10.1021/ja00164a036  0.09
2010 VELA MA, KOHN H. ChemInform Abstract: Studies on the Reactivity of Bicyclomycin 3′-O-Methanesulfonate. A Novel Ring Expansion Transformation. Cheminform. 23: no-no. DOI: 10.1002/chin.199211268  0.088
1984 Jung S, Kohn H. A new reductive procedure for the preparation of vicinal diamines and monoamines Tetrahedron Letters. 25: 399-402. DOI: 10.1016/S0040-4039(00)99894-0  0.086
2009 Zou G, You X, Kohn H, Manaka T, Iwamoto M. Solid polymerization and supramolecular chirality formation of azobenzene substituted diacetylene Langmuir-Blodgett films Thin Solid Films. 518: 750-753. DOI: 10.1016/j.tsf.2009.07.082  0.085
1987 Nguy NM, Chiu IC, Kohn H. Synthesis and reactivity of 6- and 7-methoxyindano[1,2-b]aziridines The Journal of Organic Chemistry. 52: 1649-1655. DOI: 10.1021/jo00385a001  0.085
1996 Li VS, Choi D, Tang MS, Kohn H. Concerning in vitro mitomycin-DNA alkylation Journal of the American Chemical Society. 118: 3765-3766. DOI: 10.1021/ja953367q  0.082
1995 Zhang Z, Park HG, Kohn H. Bicyclomycin oxidative transformations. Synthesis and chemical properties of bicyclomycin-5-norketone The Journal of Organic Chemistry. 60: 5346-5351.  0.079
2010 Zou G, Wang Y, Zhang Q, Kohn H, Manaka T, Iwamoto M. Molecular structure modulated properties of azobenzene-substituted polydiacetylene LB films: Chirality formation and thermal stability Polymer. 51: 2229-2235. DOI: 10.1016/j.polymer.2010.03.029  0.076
2009 Kohn H, Shino T, Ohshima Y, Manaka T, Iwamoto M. Preparation of chiral poly(diacetylene) films from 10,12-pentacosadiynoic acid using circularly polarized light Thin Solid Films. 518: 842-844. DOI: 10.1016/j.tsf.2009.07.100  0.054
2017 Kohn H. H. Steve White: A Champion for Contemporary Epilepsy Research. Neurochemical Research. PMID 28124214 DOI: 10.1007/s11064-017-2180-5  0.05
2009 Zou G, Jiang H, Kohn H, Manaka T, Iwamoto M. Control and modulation of chirality for azobenzene-substituted polydiacetylene LB films with circularly polarized light. Chemical Communications (Cambridge, England). 5627-9. PMID 19753379 DOI: 10.1039/b909085a  0.049
2015 Chiu CY, Köhn HF. The Reduced RUM as a Logit Model: Parameterization and Constraints. Psychometrika. PMID 25838247 DOI: 10.1007/s11336-015-9460-2  0.048
2010 Shrestha NK, Kohn H, Imamura M, Irie K, Ogihara H, Saji T. Electrophoretic deposition of phthalocyanine in organic solutions containing trifluoroacetic acid. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 17024-7. PMID 20886893 DOI: 10.1021/la102172t  0.046
2002 Spatz K, Köhn H, Redenbach M. Characterization of the Streptomyces violaceoruber SANK95570 plasmids pSV1 and pSV2. Fems Microbiology Letters. 213: 87-92. PMID 12127493  0.044
2011 Ohshima Y, Hirako N, Kohn H, Manaka T, Iwamoto M, Lim E, Sirringhaus H. Direct observation of electron transit in ambipolar polymer-based light-emitting transistor by optical second harmonic generation measurement Physics Procedia. 14: 226-230. DOI: 10.1016/J.Phpro.2011.05.046  0.044
2015 Brusco MJ, Köhn HF, Steinley D. An Exact Method for Partitioning Dichotomous Items Within the Framework of the Monotone Homogeneity Model. Psychometrika. PMID 25850618 DOI: 10.1007/S11336-015-9459-8  0.043
2010 Köhn HF, Steinley D, Brusco MJ. The p-median model as a tool for clustering psychological data. Psychological Methods. 15: 87-95. PMID 20230105 DOI: 10.1037/A0018535  0.04
1998 Weiner A, Ripkin DJ, Patel S, Kaufman SR, Kohn HD, Weidenthal DT. Foveal dysfunction and central visual field loss in glaucoma. Archives of Ophthalmology (Chicago, Ill. : 1960). 116: 1169-74. PMID 9747674 DOI: 10.1001/Archopht.116.9.1169  0.039
2010 Kohn H, Shino T, Ohshima Y, Manaka T, Iwamoto M. Morphological evidence of chirality in poly (diacetylene) film prepared using circularly polarized light International Journal of the Society of Material Engineering For Resources. 17: 193-196. DOI: 10.5188/ijsmer.17.193  0.038
2008 Kohn H, Ohshima Y, Manaka T, Iwamoto M. Induced optical chirality of poly(diacetylene) film by circularly polarized light and its control by changing substrate temperature Japanese Journal of Applied Physics. 47: 1359-1362. DOI: 10.1143/JJAP.47.1359  0.034
2009 Kohn H, Fukada M, Ohshima Y, Manaka T, Iwamoto M. Circular dichroism and electroluminescence of poly(diacetylene) film with chirality Materials Science- Poland. 27: 727-734.  0.034
2014 Kohn H. A mentoring program to help junior faculty members achieve scholarship success. American Journal of Pharmaceutical Education. 78: 29. PMID 24672062 DOI: 10.5688/ajpe78229  0.032
2010 Zou G, Jiang H, Zhang Q, Kohn H, Manaka T, Iwamoto M. Chiroptical switch based on azobenzene-substituted polydiacetylene LB films under thermal and photic stimuli Journal of Materials Chemistry. 20: 285-291. DOI: 10.1039/b913764e  0.032
1999 Mirzaei S, Krotla G, Knoll P, Koriska K, Köhn H. Possible effect of calcitonin deficiency on bone mass after subtotal thyroidectomy. Acta Medica Austriaca. 26: 29-31. PMID 10230474  0.031
2011 Ohshima Y, Satou H, Hirako N, Kohn H, Manaka T, Iwamoto M. Direct observation of carrier behavior leading to electroluminescence in tetracene field-effect transistor Japanese Journal of Applied Physics. 50. DOI: 10.1143/JJAP.50.04DK14  0.029
2004 Mirzaei S, Knoll P, Köhn H. [Medical aspects of objectifying torture sequels]. Wiener Klinische Wochenschrift. 116: 568-74. PMID 15471186  0.028
2015 Köhn HF, Chiu CY, Brusco MJ. Heuristic cognitive diagnosis when the Q-matrix is unknown. The British Journal of Mathematical and Statistical Psychology. 68: 268-91. PMID 25496248 DOI: 10.1111/bmsp.12044  0.028
2008 Kohn H, Ohshima Y, Manaka T, Iwamoto M. Optical chirality induced in evaporated poly(diacetylene) film by circularly polarized light Macromolecular Symposia. 268: 77-80. DOI: 10.1002/masy.200850816  0.028
2004 Guten GN, Kohn HS, Zoltan DJ, Black BB, Coran DL, Schneider JA, Pauers W. The role of the chief ethics officer in a physician's office. Clinics in Sports Medicine. 23: 243-53, vi-vii. PMID 15183570 DOI: 10.1016/j.csm.2004.01.006  0.026
2008 Manaka T, Kohn H, Ohshima Y, Lim E, Iwamoto M. Hole trapping in polydiacetylene field effect transistor studied by optical second harmonic generation Thin Solid Films. 516: 2779-2782. DOI: 10.1016/j.tsf.2007.04.116  0.026
2009 Ohshima Y, Kohn H, Lim E, Manaka T, Iwamoto M. Observation of electron injection in an organic field-effect transistor with electroluminescence Materials Science- Poland. 27: 719-726.  0.025
2015 Chiu CY, Köhn HF. A general proof of consistency of heuristic classification for cognitive diagnosis models. The British Journal of Mathematical and Statistical Psychology. PMID 25872467 DOI: 10.1111/bmsp.12055  0.024
2000 Mirzaei S, Zajicek SM, Knoll P, Lipp C, Lipp RW, Salzer H, Umek H, Kohn H. Scintimammography enhances negative predictive value of non-invasive pre-operative assessment of breast lesions. European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 26: 738-41. PMID 11087637 DOI: 10.1053/ejso.2000.0995  0.023
2007 Manaka T, Kohn H, Ohshima Y, Lim E, Iwamoto M. Direct observation of trapped carriers in polydiacetylene films by optical second harmonic generation Applied Physics Letters. 90. DOI: 10.1063/1.2734469  0.023
1998 Mirzaei S, Wagner E, Knoll P, Dunky A, Köhn H. Decisive diagnosis of seronegative polyarthritis by 3-phase bone scintigraphy. Nuklearmedizin. Nuclear Medicine. 37: 254-6. PMID 9830617  0.022
2003 Borst-Krafek B, Fink AM, Lipp C, Umek H, Köhn H, Steiner A. Proximal extent of pelvic vein thrombosis and its association with pulmonary embolism. Journal of Vascular Surgery. 37: 518-22. PMID 12618685 DOI: 10.1067/mva.2003.151  0.022
2007 Zou G, Kohn H, Ohshima Y, Manaka T, Iwamoto M. Fabricating chiral polydiacetylene film by monolayer compression and circularly polarized ultra-violet light Chemical Physics Letters. 442: 97-100. DOI: 10.1016/j.cplett.2007.05.059  0.02
1998 Warchol O, König B, Dworak E, Köhn H, Dunky A, Mostbeck A. [Value of inflammation and bone scintigraphy in differential diagnosis of painful affections of small joints]. Acta Medica Austriaca. 25: 7-12. PMID 9576018  0.02
2002 Fisher WA, Bryan A, Dervaitis KL, Silcox J, Kohn H. It ain't necessarily so: most women do not strongly prefer female obstetrician-gynaecologists. Journal of Obstetrics and Gynaecology Canada : Jogc = Journal D'ObstéTrique Et GynéCologie Du Canada : Jogc. 24: 885-8. PMID 12417903 DOI: 10.1016/S1701-2163(16)31045-3  0.02
2011 Satou H, Ohshima Y, Kohn H, Manaka T, Iwamoto M. Direct observation of space charge field in tetracene field-effect transistor using time-resolved microscopic optical second harmonic generation Journal of Applied Physics. 109. DOI: 10.1063/1.3554835  0.019
2001 Knoll P, Krotla G, Mirzaei S, Koriska K, Köhn H. Arm positioning in thallium-201 cardiac imaging. European Journal of Nuclear Medicine. 28: 254. PMID 11303898  0.019
2008 Ohshima Y, Kohn H, Lim E, Manaka T, Iwamoto M. Observation of electron injection Into organic field-effect transistor with Au electrodes using electroluminescence under AC electric field Japanese Journal of Applied Physics. 47: 1297-1300. DOI: 10.1143/JJAP.47.1297  0.017
2002 Guten GN, Kohn HS, Zoltan DJ. 'False positive' MRI of the knee: a literature review study. Wmj : Official Publication of the State Medical Society of Wisconsin. 101: 35-8. PMID 12025753  0.016
2008 Yavelsky V, Rohkin S, Shaco-Levy R, Tzikinovsky A, Amir T, Kohn H, Delgado B, Rabinovich A, Piura B, Chan G, Kalantarov G, Trakht I, Lobel L. Native human autoantibodies targeting GIPC1 identify differential expression in malignant tumors of the breast and ovary. Bmc Cancer. 8: 247. PMID 18721484 DOI: 10.1186/1471-2407-8-247  0.016
2003 Knoll P, Krotla G, Mirzaei S, Koriska K, Köhn HD. [New design concept to improve medical application software]. Acta Medica Austriaca. 30: 33-6. PMID 12752085 DOI: 10.1046/j.1563-2571.2003.03001.x  0.015
1998 Weiner A, Schmidt ME, Patel S, Gussler CH, Remler BF, Kaufman SR, Kohn HD, Weidenthal DT. Foveal outer retinal function in eyes with unexplained visual symptoms or acuity loss. Archives of Ophthalmology (Chicago, Ill. : 1960). 116: 1161-8. PMID 9747673 DOI: 10.1001/Archopht.116.9.1161  0.014
2007 Zou G, Lim E, Kajimoto N, Kohn H, Ohshima Y, Manaka T, Iwamoto M. Electrical transport properties of polydiacetylene films during thermochromic process Japanese Journal of Applied Physics, Part 1: Regular Papers and Short Notes and Review Papers. 46: 3071-3076. DOI: 10.1143/JJAP.46.3071  0.014
2008 Ohshima Y, Kohn H, Lim E, Manaka T, Iwamoto M. Observation of carrier behavior in organic field-effect transistors with electroluminescence under AC electric field Japanese Journal of Applied Physics. 47: 3200-3203. DOI: 10.1143/JJAP.47.3200  0.013
1998 Mostbeck A, Galvan G, Bauer P, Eber O, Atefie K, Dam K, Feichtinger H, Fritzsche H, Haydl H, Köhn H, König B, Koriska K, Kroiss A, Lind P, Markt B, et al. The incidence of hyperthyroidism in Austria from 1987 to 1995 before and after an increase in salt iodization in 1990. European Journal of Nuclear Medicine. 25: 367-74. PMID 9553166 DOI: 10.1007/s002590050234  0.013
2000 Knoll P, Höll K, Mirzaei S, Koriska K, Köhn H. Distributed nuclear medicine applications using World Wide Web and Java technology. European Radiology. 10: 1483-6. PMID 10997440 DOI: 10.1007/s003300000432  0.011
2001 Knoll P, Mirzaei S, Koriska K, Köhn H. Implementing a Java-based image and report distribution system in a non-picture archiving and communication environment. Journal of Digital Imaging. 14: 49. PMID 11310915  0.011
2007 Knoll P, Köhn H, Mirzaei S. Data acquisition and analysis: the strength of methodology in nuclear medicine and molecular imaging. European Journal of Nuclear Medicine and Molecular Imaging. 34: 961-2. PMID 17384948 DOI: 10.1007/s00259-007-0399-0  0.011
2006 Grassi G, Köhn H, Dapas B, Farra R, Platz J, Engel S, Cjsareck S, Kandolf R, Teutsch C, Klima R, Triolo G, Kuhn A. Comparison between recombinant baculo- and adenoviral-vectors as transfer system in cardiovascular cells. Archives of Virology. 151: 255-71. PMID 16195789 DOI: 10.1007/s00705-005-0636-4  0.01
2000 Mirzaei S, Knoll P, Köhn H. [On the article: Comparison of different methods for attenuation correction in brain PET (Nuclearmedicin 2000; 39: 505)]. Nuklearmedizin. Nuclear Medicine. 39: N95. PMID 11057410  0.01
2009 Ohshima Y, Kohn H, Manaka T, Iwamoto M. Space charge field effect on light emitting from tetracene field-effect transistor under AC electric field Thin Solid Films. 518: 583-587. DOI: 10.1016/j.tsf.2009.07.022  0.01
2008 Brusco MJ, Köhn HF. Comment on "Clustering by passing messages between data points". Science (New York, N.Y.). 319: 726; author reply 72. PMID 18258881 DOI: 10.1126/science.1150938  0.01
2007 Gsell H, Homburg N, Kohn H. Guiding the life cycle of ships Rina - International Conference On Computer Applications in Shipbuilding 2007 - Papers. 3: 149-154.  0.01
2006 Wagner F, Thomy C, Schilf M, Seefeld T, Kohn H, Vollertsen F. Laser and laser-hybrid welding of thick sheet aluminium and steel Picalo 2006 - 2nd Pacific International Conference On Applications of Laser and Optics - Conference Proceedings. 163-168.  0.01
2003 Mirzaei S, Zajicek HK, Knoll P, Hahn M, Levi M, Köhn H, Pohl W. Effect of rocaltrol on bone mass in patients with pulmonary disease treated with corticosteroids. The Journal of Asthma : Official Journal of the Association For the Care of Asthma. 40: 251-5. PMID 12807168  0.01
2003 Mirzaei S, Rodrigues M, Hoffmann B, Knoll P, Riegler-Keil M, Kreuzer W, Salzer H, Köhn H, Polyák A, Jánoki GA. Sentinel lymph node detection with large human serum albumin colloid particles in breast cancer. European Journal of Nuclear Medicine and Molecular Imaging. 30: 874-8. PMID 12677304 DOI: 10.1007/s00259-003-1147-8  0.01
2001 Mirzaei S, Schratter-Sehn AU, Knoll P, Gerber E, Kumpan W, Schiessel R, Raderer M, Köhn H. [Determination of therapy management in rectal carcinoma by staging with 18-FDG-PET]. Der Chirurg; Zeitschrift FüR Alle Gebiete Der Operativen Medizen. 72: 1058-61. PMID 11594277  0.01
2001 Mirzaei S, Knoll P, Kohn H. Diagnosis of recurrent astrocytoma with fludeoxyglucose F18 PET scanning. The New England Journal of Medicine. 344: 2030-1. PMID 11430342 DOI: 10.1056/NEJM200106283442614  0.01
2001 Mirzaei S, Knoll P, Keck A, Preitler B, Gutierrez E, Umek H, Köhn H, Pecherstorfer M. Regional cerebral blood flow in patients suffering from post-traumatic stress disorder. Neuropsychobiology. 43: 260-4. PMID 11340366  0.01
2001 Mirzaei S, Knoll P, Hoffmann B, Kreuzer W, Kohn H. Optimized mammary lymphoscintigraphy using larger colloid particles. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 42: 826. PMID 11337584  0.01
2001 Knoll P, Mirzaei S, Koriska K, Köhn H. Advanced medical imaging project. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 42: 390-1. PMID 11216540  0.01
2000 Fisher WA, Dervaitis KL, Bryan AD, Silcox J, Kohn H. SEXUAL HEALTH, REPRODUCTIVE HEALTH, SEXUAL COERCION, AND PARTNER ABUSE INDICATORS IN A CANADIAN OBSTETRICS AND GYNAECOLOGY OUTPATIENT POPULATION. Journal Sogc : Journal of the Society of Obstetricians and Gynaecologists of Canada. 22: 714-424. PMID 12457200  0.01
2000 Knoll P, Gröller E, Höll K, Mirzaei S, Koriska K, Köhn H. A Jini service to reconstruct tomographic data. Ieee Transactions On Medical Imaging. 19: 1258-61. PMID 11212375 DOI: 10.1109/42.897819  0.01
2000 Knoll P, Kenny B, Mirzaei S, Koriska K, Köhn H. Application of a "Jini-enabled" patient data storage system. Radiographics : a Review Publication of the Radiological Society of North America, Inc. 20: 1817-8. PMID 11112831 DOI: 10.1148/radiographics.20.6.g00no001817  0.01
2000 Knoll P, Mirzaei S, Koriska K, Köhn H. Solutions to some problems of iterative reconstruction algorithms for single-photon emission tomography. European Journal of Nuclear Medicine. 27: 462-3. PMID 10805122  0.01
1999 Knoll P, Mirzaei S, Müllner A, Leitha T, Koriska K, Köhn H, Neumann M. An artificial neural net and error backpropagation to reconstruct single photon emission computerized tomography data. Medical Physics. 26: 244-8. PMID 10076982  0.01
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